LOCUS       HUMPCC                  3388 bp    mRNA    linear   HUM 07-JAN-1995
DEFINITION  Human potassium channel (HPCN2) mRNA, complete cds.
ACCESSION   M55514
VERSION     M55514.1
KEYWORDS    potassium channel protein.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3388)
  AUTHORS   Philipson,L.H., Schaefer,K., LaMendola,J., Bell,G.I. and
            Steiner,D.F.
  TITLE     Sequence of a human fetal skeletal muscle potassium channel cDNA
            related to RCK4
  JOURNAL   Nucleic Acids Res. 18 (23), 7160 (1990)
   PUBMED   2263489
REFERENCE   2  (bases 1 to 3388)
  AUTHORS   Philipson,L.H., Hice,R.E., Schaefer,K., LaMendola,J., Bell,G.I.,
            Nelson,D.J. and Steiner,D.F.
  TITLE     Sequence and functional expression in Xenopus oocytes of a human
            insulinoma and islet potassium channel
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 88 (1), 53-57 (1991)
   PUBMED   1986382
COMMENT     Original source text: Human fetal skeletal muscle, cDNA to mRNA.
FEATURES             Location/Qualifiers
     source          1..3388
                     /db_xref="H-InvDB:HIT000195789"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /tissue_type="skeletal muscle"
                     /dev_stage="fetus"
     gene            1..3388
                     /gene="HPCN2"
     CDS             1155..3116
                     /gene="HPCN2"
                     /function="ion transport"
                     /codon_start=1
                     /product="potassium channel protein"
                     /protein_id="AAA60034.1"
                     /translation="MEVAMVSAESSGCNSHMPYGYAAQARARERERLAHSRRAAARAV
                     AAATAAVEGSGGSGGGSHHHHQSRGACTSHDPQSSRGSREEEATRSEKKKAHYRQSSF
                     PHCSDLMPSGSEEKILRELSEEEEDEEEEEEEEEEGRFYYSEDDHGDECSYTDLLPQD
                     EGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNE
                     YFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFV
                     REEEDRALPENEFKKQIWLLFEYPESSDPARGIAIVSVLVILISIVIFCLETLPEFRD
                     DRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFA
                     CPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVR
                     VFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHF
                     QSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGVLCAIAGVLTIALPVPVIVSNFNYF
                     YHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEEGVKESLCA
                     KEEKCQAKGDDSETDKNNCSNAKAVETDV"
BASE COUNT          835 a          813 c          846 g          894 t
ORIGIN      
        1 ttaacaagtg atcgctgctg tctaggattt tgtttctttt cgggggaacc ttgacttcct
       61 ttcccaggca atccctcctg tgctgaactc cagaggaacc aggagtcttg gggtcttctc
      121 tggggcagcc ccaaccccca cccccaggct ccagccgcga ggactctgtg cacccctcgg
      181 gccaggcaac agaacttgtt ccgtggatat ttggagcctc cacctgccaa acccgagtga
      241 ttccttttac caccccccgc cccccaccca ggatcattct tcccctcctc cagctgttgc
      301 agcttgaggg ggaaaaacaa gccagccggt ggattttctt tatttttatt tttcgccccg
      361 ccggggaagg gtgaagtgct tcttctgcat gattttggct gaagaatgct ctgcatttcc
      421 ttgatttcta tggagacctc agagctggtt ttgcttctgc tgacacctca tctagcacct
      481 tctctacctc ccagggtctt tgcctctatc tgtggtttgg cattgtacct gggtacagga
      541 agcctttgat gaacttaaaa ggagagcctg gagaatcatc ctgatagact ttgagtagaa
      601 atggctggac atacttcaaa ccacatctta acatggttcg agccatcact agaaggcaag
      661 tgctaacagt aaaggcttat ttgcatttta tttacattta atggactgag cattggccaa
      721 tttccatggc agaaaaatat atttcatttt ctaggcacaa cttctggctg tcagacactt
      781 gctgcctttg aatcttgcag caacatcact aaccacatcc cagacatatt tccaaatttc
      841 aacatctacc cccaaaacat aggtgtctga gagactccag cattttcgga cttcttagtc
      901 ttgagagtgc caggctattt atctcgacca gccaagctct ggagagcaat gttgaatccc
      961 tgagaagaga gaggcatggg gcgtgctgat ttaaaaacag aaaatgcaaa gttggagctg
     1021 aaaatatcct tagtcttcca agcaatctgc ttaagggttc caaacttacc ttaatttggt
     1081 gagaaaagaa gctgccctat ttttctttct tcttcttcta caactggaac cagccatttc
     1141 cgaaaaccac caccatggag gttgcaatgg tgagtgcgga gagctcaggg tgcaacagtc
     1201 acatgcctta tggttatgct gcccaggccc gggcccggga gcgggagagg cttgctcact
     1261 ccaggcgagc tgcagcacgt gctgttgcag cggccacagc tgctgtcgaa ggtagcgggg
     1321 gttctggtgg gggctcccac caccaccacc agtcacgcgg ggcctgtacc tcccatgacc
     1381 ctcagagcag ccggggtagt cgggaggagg aggcgacacg gtctgagaag aagaaagccc
     1441 actaccggca gagcagcttc cctcattgct ctgacctgat gcccagtggc tctgaggaga
     1501 agatcctgag ggagctgagt gaggaggagg aagatgagga ggaggaggaa gaggaggaag
     1561 aggagggaag gttttactat agtgaagatg accatggtga tgagtgttcc tacacggatc
     1621 tgctgcctca ggatgagggc ggtggcggct acagttcagt ccgctacagt gactgttgtg
     1681 aacgtgtggt gataaatgtg tcaggcctac gctttgagac ccaaatgaaa actctggccc
     1741 agtttccaga gactttgttg ggagaccctg aaaagaggac tcagtacttt gaccctttgc
     1801 gcaatgagta tttttttgac aggaaccgcc ccagctttga tgccatcttg tattattatc
     1861 aatcaggagg ccgcctgaag aggccagtca atgtcccctt tgatatcttc actgaggagg
     1921 tgaagttcta tcagttgggg gaggaggccc tgttgaagtt tcgggaggac gagggctttg
     1981 tgagagaaga ggaagacagg gccctccccg agaatgaatt taaaaagcag atttggctcc
     2041 tctttgaata tccagagagc tccgatcctg caaggggcat agccattgtg tccgtcctgg
     2101 tcatcttaat ctccattgtc atcttttgcc tggaaacctt gcctgagttt agggacgaca
     2161 gggatctcgt catggcactg agtgctggcg ggcatggtgg gttgttgaat gatacttcag
     2221 caccccatct ggagaactca gggcacacaa tattcaatga ccccttcttc atcgtggaaa
     2281 cagtctgtat tgtatggttt tcctttgagt ttgtggttcg ctgctttgct tgtcccagcc
     2341 aagcactctt cttcaaaaac atcatgaaca tcattgacat tgtctccatt ttgccttact
     2401 tcatcacact gggcactgac ctggcccagc aacagggggg tggcaatggt cagcagcagc
     2461 aggccatgtc ctttgccatc ctcagaatca ttcgtctggt ccgagtattc cggatcttca
     2521 aactctccag gcactccaaa ggcctgcaga tcctgggcca caccctcaga gccagcatgc
     2581 gggaactggg ccttctgatc ttcttcctct tcattggggt catcctcttt tctagtgctg
     2641 tgtattttgc agaggcggat gaacctacta cccatttcca aagcatccca gatgcatttt
     2701 ggtgggctgt ggtgaccatg acaactgtgg gctatgggga catgaagccc atcactgtag
     2761 ggggcaagat tgtcggggtc ctgtgtgcca ttgcgggtgt cttaaccatt gctttgccag
     2821 tgccagtgat tgtctctaac tttaactatt tctaccacag agagactgaa aatgaggaac
     2881 agacacagct aacgcagaat gcagtcagtt gtccatacct cccctctaat ttgctcaaga
     2941 aatttcggag ctctacttct tcttccctgg gggacaagtc agagtatcta gagatggaag
     3001 aaggagttaa ggaatctctg tgtgccaagg aggagaagtg tcaggccaag ggggatgaca
     3061 gtgagacaga taaaaacaac tgttctaatg caaaggctgt ggagactgat gtgtgaatct
     3121 tttttttcca cctgccactg ctcccccctc agccatcttc caaatatatt tatgcataga
     3181 gagtgcagtt atgaaaatga aatatgcaaa tgatccaatg cataccagta gtacactatt
     3241 taatggttat acatggcata attgttacta aacttgtatt acatatcaaa taaatgatac
     3301 atcttggaga agagggagga ataggagcaa tctatcttta tatttttatt agaatgcaag
     3361 aattttccac attaacctgg aaaagatg
//