LOCUS HUMCBF 3216 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human CCAAT-box-binding factor (CBF) mRNA, complete cds.
ACCESSION M37197
VERSION M37197.1
KEYWORDS CCAAT-box-binding factor; transcription factor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3216)
AUTHORS Lum,L.S., Sultzman,L.A., Kaufman,R.J., Linzer,D.I. and Wu,B.J.
TITLE A cloned human CCAAT-box-binding factor stimulates transcription
from the human hsp70 promoter
JOURNAL Mol. Cell. Biol. 10 (12), 6709-6717 (1990)
PUBMED 2247079
COMMENT Original source text: Human W138 and U2-OS cell lines, cDNA to
mRNA.
Draft entry and computer-readable sequence for [Unpublished (1990)]
kindly submitted
by B.Wu, 01-AUG-1990.
Author address: B.Wu
Dept. of Biochemistry
Northwestern University
2153 Sheridan Rd.
Evanston, IL 60208.
FEATURES Location/Qualifiers
source 1..3216
/db_xref="H-InvDB:HIT000195711"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Unassigned"
/cell_line="W38 and U2-OS"
/tissue_lib="lambda-gt11 and lambda-ZAP"
gene 1..3216
/gene="CBF"
mRNA 1..3216
/gene="CBF"
/product="CCAAT-box-binding factor"
gene 12..3008
/gene="CEBP"
CDS 12..3008
/gene="CEBP"
/codon_start=1
/product="CCAAT-box-binding factor"
/protein_id="AAA51924.1"
/db_xref="GDB:G00-128-839"
/translation="MAAVKEPLEFHAKRPWRPEEAVEDPDEEDEDNTSEAENGFSLEE
VLRLGGTKQDYLMLATLDENEEVIDGGKKGAIDDLQQGELEAFIQNLNLAKYTKASLI
EEDEPAEKENSSKKEVKIPKINNKNTAESQRTSVNKVKNKNRPEPHSDENGSTTPKVK
KDKQNIFEFFERQTLLLRPGGKWYDLEYSNEYSLKPQPQDVVSKYKTLAQKLYQHEIN
LFKSKTNSQKGASSTWMKAIVSSGTLGDRMAAMILLIQDDAVHTLQFVETLVNLVKKK
GSKQQCLMALDTFKELLITDLLPDNRKLRIFSQRPFDKLEQLSSGNKDSRDRRLILWY
FEHQLKHLVAEFVQVLETLSHDTLVTTKTRALTVAHELLCNKPEEEKALLVQVVNKLG
DPQNRIATKASHLLETLLCKHPNMKGVVSGEVERLLFRSNISSKAQYYAICFLNQMAL
SHEESELANKLITVYFCFFRTCVKKKDVESKMLSALLTGVNRAYPYSQTGDDKVREQI
DTLFKVLHIVNFNTSVQALMLLFQVMNSQQTISDRYYTALYRKMLDPGLMTCSKQAMF
LNLVYKSLKADIVLRRVKAFVKGLLQVTCQQMPPFICGALYLVSEILKAKPGLRSQLD
DHPESDDEENFIDANDDEDMEKFTDADKETEIVKKLETEETVPETDVETKKPEVASWV
HFDNLKGGKQLNKYDPFSRNPLFCGAENTSLWELKKLSVHFHPSVALFAKTILQGNYI
QYSGDPLQDFTLMRFLDRFVYRNPKPHKGKENTDSVVMQPKRKHFIKDIRHLPVNSKE
FLAKEESQIPVDEVFFHRYYKKVAVKEKQKRDADEESIEDVDDEEFEELIDTFEDDNC
FSSGKDDMDFAGNVKKRTKGAKDNTLDEDSEGSDDELGNLDDDEVSLGSMDDEEFAEV
DEDGGTFMDVLDDESESVPELEVHSKVSTKKSKRKGTDDFDFAGSFQGPRKKKRNLND
SSLFVSAEEFGHLLDENMGSKFDNIA"
BASE COUNT 1123 a 539 c 722 g 832 t
ORIGIN
1 gctttgccgc catggccgca gtcaaggagc ctttggagtt ccatgccaag cggccttggc
61 gccccgagga ggcagtagaa gatccggacg aggaggatga ggataatact agtgaagccg
121 agaatgggtt ctccctggag gaagtgttac ggctcggagg caccaagcaa gattacctta
181 tgctggctac tttggatgag aatgaggaag tgatagatgg aggcaaaaaa ggagcaatcg
241 atgaccttca gcaaggtgaa ttggaagcat ttattcaaaa tcttaatttg gcgaagtata
301 caaaagcttc cttaattgaa gaagatgaac cagctgaaaa agaaaattcc agcaaaaaag
361 aagtaaaaat acctaaaata aataataaaa atacagcaga aagtcaaagg acatcagtta
421 ataaggtgaa aaataagaat aggccagaac cacattctga tgagaatggc agtaccacac
481 cgaaagtaaa gaaagataaa cagaacatct ttgaattttt tgagagacag actttgttac
541 ttaggcctgg aggcaaatgg tatgatctgg agtacagcaa tgaatattct ttgaaacccc
601 agcctcagga tgttgtatct aagtacaaaa cccttgctca gaagctgtat cagcatgaaa
661 tcaacttatt caaaagtaag acgaatagtc aaaagggagc ctcttctacc tggatgaagg
721 caattgtgtc atcggggaca ctaggtgaca ggatggcagc catgattctt cttattcagg
781 atgatgccgt tcacacactt cagtttgtag aaactcttgt gaaccttgtt aaaaagaagg
841 gcagcaaaca gcagtgcctt atggccttgg atactttcaa agagttgctt atcacagacc
901 ttttgccaga caatcggaag ctgaggattt tcagccagcg tccttttgac aaactggaac
961 agttgtccag tggcaacaag gactcaagag atagaagact gatattatgg tattttgaac
1021 accagctgaa acacttagtg gctgaatttg tgcaggtctt agaaacttta agtcatgata
1081 cattagtaac cactaaaact cgagccctta ccgtggctca tgagctgctt tgtaacaagc
1141 ctgaggaaga aaaggctctt cttgtgcaag tggtaaataa actgggagat cctcagaaca
1201 gaattgccac aaaagcatcc catctgttag agacattact ttgtaaacat cccaatatga
1261 aaggagttgt gtctggtgaa gtagaaaggc tactcttccg ctcaaatatc agctccaaag
1321 ctcaatatta tgcaatttgc tttttaaatc aaatggctct gtcccatgaa gaaagtgaat
1381 tggctaacaa attaataact gtttactttt gcttttttcg gacttgtgtc aaaaaaaaag
1441 atgttgaatc aaaaatgctt agcgcccttt taacaggtgt gaatagggca tacccttatt
1501 cccagactgg tgatgacaaa gtaagggagc agattgacac actgtttaaa gtgttgcata
1561 ttgtgaattt taataccagt gtccaggctt taatgttgct tttccaagta atgaattctc
1621 agcagacaat atcggatcga tattacacag cattatacag gaagatgttg gatccagggt
1681 tgatgacgtg ttccaagcaa gctatgtttc ttaaccttgt ctacaaatct ctgaaagctg
1741 acattgtgtt gcgccgggtg aaggcttttg tgaaggggtt acttcaagtt acttgtcaac
1801 agatgccacc atttatatgt ggagctttat atcttgtgtc tgagatcctt aaagcaaaac
1861 caggtttaag aagccaacta gatgatcatc cggagtctga tgatgaagaa aattttattg
1921 atgcaaatga tgatgaagac atggaaaaat tcactgatgc agacaaagaa acagagatag
1981 tgaaaaaact tgagacagag gaaacagttc ctgaaactga tgtagaaacc aaaaaaccag
2041 aggttgcttc ctgggtgcac tttgataatt tgaaaggtgg gaaacagtta aataaatacg
2101 atccattcag tagaaaccct ctgttctgtg gagctgaaaa tacaagtctt tgggaactca
2161 aaaagttatc tgtgcatttt catccctccg tggccctttt tgcaaagacc atccttcagg
2221 gaaactatat tcagtattca ggggacccac tgcaggattt cactctaatg agatttttgg
2281 atcgatttgt ataccgaaat ccaaagcccc ataaaggcaa agaaaacaca gatagtgttg
2341 tgatgcagcc gaaaagaaaa cattttatta aggatattcg tcatcttcct gtgaacagta
2401 aggagttcct tgcaaaagaa gaaagccaaa taccagtgga tgaagtgttt ttccacaggt
2461 attataaaaa agttgctgtt aaagagaaac aaaaacggga tgcagatgaa gaaagtatag
2521 aagacgtgga tgatgaagaa tttgaagagc tgattgacac atttgaagat gataactgtt
2581 tcagctctgg aaaggatgat atggattttg ctggaaacgt gaaaaagaga acaaaaggag
2641 ctaaggataa cacattagat gaagattcag aaggtagtga tgatgaactt ggtaacctgg
2701 atgacgatga agtttcttta ggaagtatgg atgatgaaga atttgctgaa gttgatgaag
2761 atggaggaac attcatggat gtgttagatg atgaaagtga gagcgttcca gaacttgaag
2821 tccactccaa agtcagtact aagaaaagca agagaaaagg tacagatgat tttgactttg
2881 ctggctcatt tcaagggcca agaaaaaaga aaagaaactt aaatgattcc agcctatttg
2941 tatctgctga agagtttggc catctattgg atgaaaatat gggatccaag tttgataaca
3001 ttgcatgaat gccatggcta acaaagataa tgcaagtctc aaacagctta gatgggaggc
3061 tgaacgtgat gactggctac acaacagaga tgcaaaaagt atcatcaaga aaaagaaaca
3121 ttttaaaaag aagaggatta aaaccactca aaaaactaaa aaacaaagga aatgagttat
3181 taatgtaaat tatagattaa aattctactt acatct
//