LOCUS       HUMADRA2RA              2072 bp    DNA     linear   HUM 30-OCT-1994
DEFINITION  Human alpha-2-adrenergic receptor (alpha-2 c2) gene, complete cds.
ACCESSION   M34041
VERSION     M34041.1
KEYWORDS    alpha-2-adrenergic receptor; plasma membrane protein;
            receptor-coupled G protein.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2072)
  AUTHORS   Lomasney,J.W., Lorenz,W., Allen,L.F., King,K., Regan,J.W.,
            Yang-Feng,T.L., Caron,M.G. and Lefkowitz,R.J.
  TITLE     Expansion of the alpha 2-adrenergic receptor family: cloning and
            characterization of a human alpha 2-adrenergic receptor subtype,
            the gene for which is located on chromosome 2
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 87 (13), 5094-5098 (1990)
   PUBMED   2164221
COMMENT     Original source text: Human placenta DNA, clone alpha-2 C2.
            Draft entry and computer-readable sequence for [1] kindly submitted
            by J.W.Lomasney, 03-MAY-1990, for release after publication.
FEATURES             Location/Qualifiers
     source          1..2072
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /map="2"
     gene            413..1765
                     /gene="ADRA2B"
     CDS             413..1765
                     /gene="ADRA2B"
                     /note="alpha-2-adrenergic receptor (alpha-2 C2) old gene
                     name 'ADRA2RL1'"
                     /codon_start=1
                     /protein_id="AAA51666.1"
                     /db_xref="GDB:G00-120-539"
                     /translation="MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLR
                     APQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVH
                     LCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRG
                     RPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGES
                     KQPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAA
                     LPNSGQGQKEGVCGASPEDEAEEEEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSR
                     VLATLRGQVLLGRGVGAIGGQWWRRRAHVTREKRFTFVLAVVIGVFVLCWFPFFFSYS
                     LGAICPKHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRILCRPWTQTAW
                     "
BASE COUNT          316 a          705 c          660 g          391 t
ORIGIN      Chromosome 2.
        1 ctgcaggcgc ggctggggcg aaacgtgcga gctgagcggg cgcaaggtcc tccgcgcctc
       61 ctttaagaac cggcccagcc cggcccgcgc ccccagagcg tacggcatcc gcgtggcgga
      121 gggcgcgact ttctccggtc ccgggcggga cggggacggc ggcgggacaa cttgggaaac
      181 ttctctgggg cggacggcag ggaccccggg caccgtggag gaggatgtag gagggcggct
      241 gctggtcctg ggtgttcccg acctcctagg ccccgctcgt ccaggccatg gggctccagc
      301 gccctcgcgg cgccggaggg gcgacgctct tgtctagccg agccgggcag cgctgtcgtc
      361 cacggtgcgc actgggcggg cagcgctccc tctgcccacc tcccgccccg tcatggacca
      421 ccaggacccc tactccgtgc aggccacagc ggccatagcg gcggccatca ccttcctcat
      481 tctctttacc atcttcggca acgctctggt catcctggct gtgttgacca gccgctcgct
      541 gcgcgcccct cagaacctgt tcctggtgtc gctggccgcc gccgacatcc tggtggccac
      601 gctcatcatc cctttctcgc tggccaacga gctgctgggc tactggtact tccggcgcac
      661 gtggtgcgag gtgtacctgg cgctcgacgt gctcttctgc acctcgtcca tcgtgcacct
      721 gtgcgccatc agcctggacc gctactgggc cgtgagccgc gcgctggagt acaactccaa
      781 gcgcaccccg cgccgcatca agtgcatcat cctcactgtg tggctcatcg ccgccgtcat
      841 ctcgctgccg cccctcatct acaagggcga ccagggcccc cagccgcgcg ggcgccccca
      901 gtgcaagctc aaccaggagg cctggtacat cctggcctcc agcatcggat ctttctttgc
      961 tccttgcctc atcatgatcc ttgtctacct gcgcatctac ctgatcgcca aacgcagcaa
     1021 ccgcagaggt cccagggcca agggggggcc tgggcagggt gagtccaagc agccccgacc
     1081 cgaccatggt ggggctttgg cctcagccaa actgccagcc ctggcctctg tggcttctgc
     1141 cagagaggtc aacggacact cgaagtccac tggggagaag gaggaggggg agacccctga
     1201 agatactggg acccgggcct tgccacccag ttgggctgcc cttcccaact caggccaggg
     1261 ccagaaggag ggtgtttgtg gggcatctcc agaggatgaa gctgaagagg aggaagagga
     1321 ggaggaggag gaggaagagt gtgaacccca ggcagtgcca gtgtctccgg cctcagcttg
     1381 cagccccccg ctgcagcagc cacagggctc ccgggtgctg gccaccctac gtggccaggt
     1441 gctcctgggc aggggcgtgg gtgctatagg tgggcagtgg tggcgtcgaa gggcgcacgt
     1501 gacccgggag aagcgcttca ccttcgtgct ggctgtggtc attggcgttt ttgtgctctg
     1561 ctggttcccc ttcttcttca gctacagcct gggcgccatc tgcccgaagc actgcaaggt
     1621 gccccatggc ctcttccagt tcttcttctg gatcggctac tgcaacagct cactgaaccc
     1681 tgttatctac accatcttca accaggactt ccgccgtgcc ttccggagga tcctgtgccg
     1741 cccgtggacc cagacggcct ggtgagcccg cctgcgctgc ccctgtgggt tggtgcggtg
     1801 gcgccggggt caccctgctt cttgccctgc tgtgtgtggc tgcctcccct gggctttctg
     1861 ctccctgccc agatcctgta ggcctcatct taggaacccc ttgggagggg tgggcagggg
     1921 ggctgctagc aagggtccca gtgaagcttc cccttgccgg cttagctgtg ggggacccct
     1981 tctccaccct ctccctgagc acaggccgat ggaggtggtt caaatcctct ggaacatagc
     2041 caagaccagg agaagagaga gcactttctt cc
//