LOCUS       HUMIL7AA                1658 bp    mRNA    linear   HUM 06-JAN-1995
DEFINITION  Human interleukin-7 receptor (IL-7) mRNA, complete cds.
ACCESSION   M29696
VERSION     M29696.1
KEYWORDS    interleukin 7 receptor.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1658)
  AUTHORS   Goodwin,R.G., Friend,D., Ziegler,S.F., Jerzy,R., Falk,B.A.,
            Gimpel,S., Cosman,D., Dower,S.K., March,C.J., Namen,A.E. and
            Park,L.S.
  TITLE     Cloning of the human and murine interleukin-7 receptors:
            demonstration of a soluble form and homology to a new receptor
            superfamily
  JOURNAL   Cell 60 (6), 941-951 (1990)
   PUBMED   2317865
COMMENT     Original source text: Human pre-B cell line IxN/2b, cDNA to mRNA,
            clone H20.
            Draft entry and computer-readable sequence for [1] kindly submitted
            by R.G.Goodwin, 03-NOV-1989.
FEATURES             Location/Qualifiers
     source          1..1658
                     /db_xref="H-InvDB:HIT000195333"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /map="Unassigned"
     gene            1..1658
                     /gene="IL7R"
     CDS             23..1402
                     /gene="IL7R"
                     /note="interleukin-7 receptor precursor"
                     /codon_start=1
                     /protein_id="AAA59157.1"
                     /db_xref="GI:307065"
                     /db_xref="GDB:G00-127-886"
                     /translation="MTILGTTFGMVFSLLQVVSGESGYAQNGDLEDAELDDYSFSCYS
                     QLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLI
                     GKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVIYREGANDFVVTFNTSHLQKKYV
                     KVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWS
                     EWSPSYYFRTPEINNSSGEMDPILLTISILSFFSVALLVILACVLWKKRIKPIVWPSL
                     PDHKKTLEHLCKKPRKNLNVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEE
                     SEKQRLGGDVQSPNCPSEDVVVTPESFGRDSSLTCLAGNVSACDAPILSSSRSLDCRE
                     SGKNGPHVYQDLLLSLGTTNSTLPPPFSLQSGILTLNPVAQGQPILTSLGSNQEEAYV
                     TMSSFYQNQ"
     sig_peptide     23..82
                     /gene="IL7R"
                     /note="interleukin-7 receptor signal peptide"
     mat_peptide     83..1399
                     /gene="IL7R"
                     /product="interleukin-7 receptor"
BASE COUNT          493 a          364 c          363 g          438 t
ORIGIN      
        1 ctctctctct atctctctca gaatgacaat tctaggtaca acttttggca tggttttttc
       61 tttacttcaa gtcgtttctg gagaaagtgg ctatgctcaa aatggagact tggaagatgc
      121 agaactggat gactactcat tctcatgcta tagccagttg gaagtgaatg gatcgcagca
      181 ttcactgacc tgtgcttttg aggacccaga tgtcaacacc accaatctgg aatttgaaat
      241 atgtggggcc ctcgtggagg taaagtgcct gaatttcagg aaactacaag agatatattt
      301 catcgagaca aagaaattct tactgattgg aaagagcaat atatgtgtga aggttggaga
      361 aaagagtcta acctgcaaaa aaatagacct aaccactata gttaaacctg aggctccttt
      421 tgacctgagt gtcatctatc gggaaggagc caatgacttt gtggtgacat ttaatacatc
      481 acacttgcaa aagaagtatg taaaagtttt aatgcatgat gtagcttacc gccaggaaaa
      541 ggatgaaaac aaatggacgc atgtgaattt atccagcaca aagctgacac tcctgcagag
      601 aaagctccaa ccggcagcaa tgtatgagat taaagttcga tccatccctg atcactattt
      661 taaaggcttc tggagtgaat ggagtccaag ttattacttc agaactccag agatcaataa
      721 tagctcaggg gagatggatc ctatcttact aaccatcagc attttgagtt ttttctctgt
      781 cgctctgttg gtcatcttgg cctgtgtgtt atggaaaaaa aggattaagc ctatcgtatg
      841 gcccagtctc cccgatcata agaagactct ggaacatctt tgtaagaaac caagaaaaaa
      901 tttaaatgtg agtttcaatc ctgaaagttt cctggactgc cagattcata gggtggatga
      961 cattcaagct agagatgaag tggaaggttt tctgcaagat acgtttcctc agcaactaga
     1021 agaatctgag aagcagaggc ttggagggga tgtgcagagc cccaactgcc catctgagga
     1081 tgtagtcgtc actccagaaa gctttggaag agattcatcc ctcacatgcc tggctgggaa
     1141 tgtcagtgca tgtgacgccc ctattctctc ctcttccagg tccctagact gcagggagag
     1201 tggcaagaat gggcctcatg tgtaccagga cctcctgctt agccttggga ctacaaacag
     1261 cacgctgccc cctccatttt ctctccaatc tggaatcctg acattgaacc cagttgctca
     1321 gggtcagccc attcttactt ccctgggatc aaatcaagaa gaagcatatg tcaccatgtc
     1381 cagcttctac caaaaccagt gaagtgtaag aaacccagac tgaacttacc gtgagcgaca
     1441 aagatgattt aaaagggaag tctagagttc ctagtctccc tcacagcaca gagaagacaa
     1501 aattagcaaa accccactac acagtctgca agattctgaa acattgcttt gaccactctt
     1561 cctgagttca gtggcactca acatgagtca agagcatcct gcttctacca tgtggatttg
     1621 gtcacaaggt ttaaggtgac ccaatgattc agctattt
//