LOCUS HUMIL7AA 1658 bp mRNA linear HUM 06-JAN-1995
DEFINITION Human interleukin-7 receptor (IL-7) mRNA, complete cds.
ACCESSION M29696
VERSION M29696.1
KEYWORDS interleukin 7 receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1658)
AUTHORS Goodwin,R.G., Friend,D., Ziegler,S.F., Jerzy,R., Falk,B.A.,
Gimpel,S., Cosman,D., Dower,S.K., March,C.J., Namen,A.E. and
Park,L.S.
TITLE Cloning of the human and murine interleukin-7 receptors:
demonstration of a soluble form and homology to a new receptor
superfamily
JOURNAL Cell 60 (6), 941-951 (1990)
PUBMED 2317865
COMMENT Original source text: Human pre-B cell line IxN/2b, cDNA to mRNA,
clone H20.
Draft entry and computer-readable sequence for [1] kindly submitted
by R.G.Goodwin, 03-NOV-1989.
FEATURES Location/Qualifiers
source 1..1658
/db_xref="H-InvDB:HIT000195333"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Unassigned"
gene 1..1658
/gene="IL7R"
CDS 23..1402
/gene="IL7R"
/note="interleukin-7 receptor precursor"
/codon_start=1
/protein_id="AAA59157.1"
/db_xref="GDB:G00-127-886"
/translation="MTILGTTFGMVFSLLQVVSGESGYAQNGDLEDAELDDYSFSCYS
QLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLI
GKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVIYREGANDFVVTFNTSHLQKKYV
KVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWS
EWSPSYYFRTPEINNSSGEMDPILLTISILSFFSVALLVILACVLWKKRIKPIVWPSL
PDHKKTLEHLCKKPRKNLNVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEE
SEKQRLGGDVQSPNCPSEDVVVTPESFGRDSSLTCLAGNVSACDAPILSSSRSLDCRE
SGKNGPHVYQDLLLSLGTTNSTLPPPFSLQSGILTLNPVAQGQPILTSLGSNQEEAYV
TMSSFYQNQ"
sig_peptide 23..82
/gene="IL7R"
/note="interleukin-7 receptor signal peptide"
mat_peptide 83..1399
/gene="IL7R"
/product="interleukin-7 receptor"
BASE COUNT 493 a 364 c 363 g 438 t
ORIGIN
1 ctctctctct atctctctca gaatgacaat tctaggtaca acttttggca tggttttttc
61 tttacttcaa gtcgtttctg gagaaagtgg ctatgctcaa aatggagact tggaagatgc
121 agaactggat gactactcat tctcatgcta tagccagttg gaagtgaatg gatcgcagca
181 ttcactgacc tgtgcttttg aggacccaga tgtcaacacc accaatctgg aatttgaaat
241 atgtggggcc ctcgtggagg taaagtgcct gaatttcagg aaactacaag agatatattt
301 catcgagaca aagaaattct tactgattgg aaagagcaat atatgtgtga aggttggaga
361 aaagagtcta acctgcaaaa aaatagacct aaccactata gttaaacctg aggctccttt
421 tgacctgagt gtcatctatc gggaaggagc caatgacttt gtggtgacat ttaatacatc
481 acacttgcaa aagaagtatg taaaagtttt aatgcatgat gtagcttacc gccaggaaaa
541 ggatgaaaac aaatggacgc atgtgaattt atccagcaca aagctgacac tcctgcagag
601 aaagctccaa ccggcagcaa tgtatgagat taaagttcga tccatccctg atcactattt
661 taaaggcttc tggagtgaat ggagtccaag ttattacttc agaactccag agatcaataa
721 tagctcaggg gagatggatc ctatcttact aaccatcagc attttgagtt ttttctctgt
781 cgctctgttg gtcatcttgg cctgtgtgtt atggaaaaaa aggattaagc ctatcgtatg
841 gcccagtctc cccgatcata agaagactct ggaacatctt tgtaagaaac caagaaaaaa
901 tttaaatgtg agtttcaatc ctgaaagttt cctggactgc cagattcata gggtggatga
961 cattcaagct agagatgaag tggaaggttt tctgcaagat acgtttcctc agcaactaga
1021 agaatctgag aagcagaggc ttggagggga tgtgcagagc cccaactgcc catctgagga
1081 tgtagtcgtc actccagaaa gctttggaag agattcatcc ctcacatgcc tggctgggaa
1141 tgtcagtgca tgtgacgccc ctattctctc ctcttccagg tccctagact gcagggagag
1201 tggcaagaat gggcctcatg tgtaccagga cctcctgctt agccttggga ctacaaacag
1261 cacgctgccc cctccatttt ctctccaatc tggaatcctg acattgaacc cagttgctca
1321 gggtcagccc attcttactt ccctgggatc aaatcaagaa gaagcatatg tcaccatgtc
1381 cagcttctac caaaaccagt gaagtgtaag aaacccagac tgaacttacc gtgagcgaca
1441 aagatgattt aaaagggaag tctagagttc ctagtctccc tcacagcaca gagaagacaa
1501 aattagcaaa accccactac acagtctgca agattctgaa acattgcttt gaccactctt
1561 cctgagttca gtggcactca acatgagtca agagcatcct gcttctacca tgtggatttg
1621 gtcacaaggt ttaaggtgac ccaatgattc agctattt
//