LOCUS HUMPROTP 1887 bp mRNA linear HUM 27-APR-1993
DEFINITION Human endomembrane proton pump subunit mRNA, complete cds.
ACCESSION M25809
VERSION M25809.1
KEYWORDS ATPase; proton pump.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1887)
AUTHORS Sudhof,T.C., Fried,V.A., Stone,D.K., Johnston,P.A. and Xie,X.S.
TITLE Human endomembrane H+ pump strongly resembles the ATP-synthetase of
Archaebacteria
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86 (16), 6067-6071 (1989)
PUBMED 2527371
COMMENT Original source text: Human kidney, cDNA to mRNA.
Draft entry and clean copy of sequence [1] kindly submitted by
T.C.Suedhof 24-JUN-1989.
FEATURES Location/Qualifiers
source 1..1887
/db_xref="H-InvDB:HIT000195015"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 56..1591
/note="proton pump 58 kDa subunit"
/codon_start=1
/protein_id="AAA36498.1"
/translation="MEIDSRPGGLPGSSCNLGAAREHMQAVTRNYITHPRVTYRTVCS
VNGPLVVLDRVKFAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKT
TCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHSRIYPEE
MIQTGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDN
FAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEF
LAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVE
GRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSR
LMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKF
EKNFINQGPYENRSMFESLDLSWKLLRIFPKEMLKRIPQAVIDEFYSREGRLQDLAPD
TAL"
BASE COUNT 404 a 580 c 533 g 370 t
ORIGIN
1 tcgcccaatt ccgggctcag acactgggct cccagctggg gactgctcca tggccatgga
61 gatagacagc aggcctgggg ggctccccgg cagtagctgc aacctaggtg cagcccgaga
121 acacatgcag gcggtcaccc gaaactacat cacccacccc cgtgtcacct acaggactgt
181 gtgcagcgtg aacgggcccc tggtggtgct ggaccgggtc aagtttgccc agtatgcgga
241 gatcgtccac ttcaccctcc cagatgggac tcagaggagc gggcaggtgc ttgaggtggc
301 tggcaccaag gcgattgttc aggtgtttga agggacatca gggatcgatg ccaggaagac
361 cacttgcgaa tttacagggg acatcctacg aactccggtg tcagaggaca tgctgggtcg
421 ggttttcaat ggctccggca agcccattga caaggggcca gtggtcatgg cggaggactt
481 tctggatatc aatggccagc ccatcaaccc gcactcccgc atctaccccg aggagatgat
541 tcagacgggc atttctccta ttgacgtcat gaacagcatt gcccgcggcc agaagatccc
601 catcttctca gcagccgggc tcccccacaa tgagattgcc gctcagatct gccgccaggc
661 ggggctggtg aagaagtcca aggctgtgct ggattaccat gacgacaact tcgccatcgt
721 ctttgcagcc atgggggtga acatggagac agccagattc ttcaagtctg actttgagca
781 gaatggaacc atggggaacg tctgcctctt cctgaacttg gccaatgacc ccacgatcga
841 gcggatcatc accccgcgcc tggcgctgac cactgctgaa ttccttgcct accagtgtga
901 gaagcatgtg ctggtcatac tgacggacat gagttcctat gcagaggcct tgcgggaggt
961 ctctgctgct agagaggagg tgcctgggcg ccgagggttt cctggatata tgtacacaga
1021 cctggccacc atctacgagc gggcgggccg tgtggagggt cggggaggat ccatcacaca
1081 gatccccatc ctcaccatgc ccaacgacga tatcacccac cctatcccag acttgacggg
1141 cttcatcaca gagggacaga tctacgtgga cagacagctt cacaacagac agatctaccc
1201 ccccatcaac gtgctccctt ccctgtcgcg gctgatgaag tcagccattg gggaaggcat
1261 gacaagaaag gaccatggag atgtctccaa ccagctgtac gcctgctatg ccatcgggaa
1321 ggacgtgcag gccatgaagg cagtagttgg ggaggaggcg ctcacctctg aggacctgct
1381 ctacctggaa ttcctgcaga agtttgagaa gaacttcatc aatcagggcc cctacgagaa
1441 ccgctcgatg ttcgagtcgc tggaccttag ctggaagctg ctgcgcatct tccccaagga
1501 gatgctgaag cgcattccgc aggccgtgat cgacgagttc tattcccgcg aggggcggct
1561 gcaggacctc gcgcctgaca ctgcgctcta gccccgcgcg ccgtggcacc ccaacaccgg
1621 caggaaccta ccctcggctc ccgggtctcc ccgtccctcg ccacccctaa ccagcggctt
1681 tcgcgccgcc ctccgccctc cgtggctccg aggtggtggg gggcgccgca gtcatccctt
1741 tcctcgctcg attccttttc ccgcgctcca tgcctccccc tcagctcccg gtgctgcgga
1801 agaactgaag gttcatgcct actctgacgg gagcatctgt attttttatg ttaaaagccc
1861 acaaaataaa aataaaaatg aactgag
//