LOCUS HUMCFX 1414 bp mRNA linear HUM 01-NOV-1994
DEFINITION Human blood-coagulation factor X mRNA, complete cds.
ACCESSION M22613
VERSION M22613.1
KEYWORDS coagulation factor X.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1414)
AUTHORS Kaul,R.K., Hildebrand,B., Roberts,S. and Jagadeeswaran,P.
TITLE Isolation and characterization of human blood-coagulation factor X
cDNA
JOURNAL Gene 41 (2-3), 311-314 (1986)
PUBMED 3011603
COMMENT Original source text: Human liver, cDNA to mRNA, clone pKT218.
FEATURES Location/Qualifiers
source 1..1414
/db_xref="H-InvDB:HIT000194853"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="13q34"
gene 1..1414
/gene="F10"
mRNA <1..1414
/gene="F10"
/product="coagulation factor X mRNA"
CDS <1..1404
/gene="F10"
/note="coagulation factor X precursor"
/codon_start=1
/protein_id="AAA51984.1"
/db_xref="GDB:G00-119-890"
/translation="LLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETC
SYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
RRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIV
GGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFEGDRNTEQEE
GGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMT
QKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQED
ACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGL
PKAKSHAPEVITSSPLK"
sig_peptide <1..66
/gene="F10"
/note="coagulation factor X signal peptide"
mat_peptide 67..483
/gene="F10"
/product="coagulation factor X light chain"
mat_peptide 493..1401
/gene="F10"
/product="coagulation factor X heavy chain"
mat_peptide 493..648
/gene="F10"
/product="coagulation factor X activation peptide"
BASE COUNT 358 a 407 c 426 g 223 t
ORIGIN
1 ctgctcgggg aaagtctgtt catccgcagg gagcaggcca acaacatcct ggcgagggtc
61 acgagggcca attcctttct tgaagagatg aagaaaggac acctcgaaag agagtgcatg
121 gaagagacct gctcatacga agaggcccgc gaggtctttg aggacagcga caagacgaat
181 gaattctgga ataaatacaa agatggcgac cagtgtgaga ccagtccttg ccagaaccag
241 ggcaaatgta aagacggcct cggggaatac acctgcacct gtttagaagg attcgaaggc
301 aaaaactgtg aattattcac acggaagctc tgcagcctgg acaacgggga ctgtgaccag
361 ttctgccacg aggaacagaa ctctgtggtg tgctcctgcg cccgcgggta caccctggct
421 gacaacggca aggcctgcat tcccacaggg ccctacccct gtgggaaaca gaccctggaa
481 cgcaggaaga ggtcagtggc ccaggccacc agcagcagcg gggaggcccc tgacagcatc
541 acatggaagc catatgatgc agccgacctg gaccccaccg agaacccctt cgacctgctt
601 gacttcaacc agacgcagcc tgagaggggc gacaacaacc tcaccaggat cgtgggaggc
661 caggaatgca aggacgggga gtgtccctgg caggccctgc tcatcaatga ggaaaacgag
721 ggtttctgtg gtggaaccat tctgagcgag ttctacatcc taacggcagc ccactgtctc
781 taccaagcca agagattcga aggggaccgg aacacggagc aggaggaggg cggtgaggcg
841 gtgcacgagg tggaggtggt catcaagcac aaccggttca caaaggagac ctatgacttc
901 gacatcgccg tgctccggct caagaccccc atcaccttcc gcatgaacgt ggcgcctgcc
961 tgcctccccg agcgtgactg ggccgagtcc acgctgatga cgcagaagac ggggattgtg
1021 agcggcttcg ggcgcaccca cgagaagggc cggcagtcca ccaggctcaa gatgctggag
1081 gtgccctacg tggaccgcaa cagctgcaag ctgtccagca gcttcatcat cacccagaac
1141 atgttctgtg ccggctacga caccaagcag gaggatgcct gccaggggga cagcgggggc
1201 ccgcacgtca cccgcttcaa ggacacctac ttcgtgacag gcatcgtcag ctggggagag
1261 ggctgtgccc gtaaggggaa gtacgggatc tacaccaagg tcaccgcctt cctcaagtgg
1321 atcgacaggt ccatgaaaac caggggcttg cccaaggcca agagccatgc cccggaggtc
1381 ataacgtcct ctccattaaa gtgagatccc actc
//