LOCUS HUMIL1BA 1497 bp mRNA linear HUM 06-JAN-1995
DEFINITION Human interleukin 1-beta (IL1B) mRNA, complete cds.
ACCESSION M15330
VERSION M15330.1
KEYWORDS interleukin 1-beta.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1497)
AUTHORS Nishida,T., Nishino,N., Takano,M., Kawai,K., Bando,K., Masui,Y.,
Nakai,S. and Hirai,Y.
TITLE cDNA cloning of IL-1 alpha and IL-1 beta from mRNA of U937 cell
line
JOURNAL Biochem. Biophys. Res. Commun. 143 (1), 345-352 (1987)
PUBMED 3493774
COMMENT Original source text: Human (cell line U937), cDNA to mRNA, clone
pcD-GIF-16.
FEATURES Location/Qualifiers
source 1..1497
/db_xref="H-InvDB:HIT000194388"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="2q13-q21"
/cell_line="U937"
gene 1..1497
/gene="IL1B"
mRNA <1..1497
/gene="IL1B"
/note="G00-120-094"
CDS 87..896
/gene="IL1B"
/codon_start=1
/product="interleukin 1-beta"
/protein_id="AAA59135.1"
/db_xref="GDB:G00-120-094"
/translation="MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPL
DGGIQLRISDHHYSKGFRQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIFEEEP
IFFDTWDNEAYVHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSM
SFVQGEESNDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFN
KIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDFTMQFVSS"
BASE COUNT 411 a 365 c 331 g 390 t
ORIGIN chromosome 2q13-q21.
1 accaacctct tcgaggcaca aggcacaaca ggctgctctg ggattctctt cagccaatct
61 tcattgctca agtgtctgaa gcagccatgg cagaagtacc tgagctcgcc agtgaaatga
121 tggcttatta cagtggcaat gaggatgact tgttctttga agctgatggc cctaaacaga
181 tgaagtgctc cttccaggac ctggacctct gccctctgga tggcggcatc cagctacgaa
241 tctccgacca ccactacagc aagggcttca ggcaggccgc gtcagttgtt gtggccatgg
301 acaagctgag gaagatgctg gttccctgcc cacagacctt ccaggagaat gacctgagca
361 ccttctttcc cttcatcttt gaagaagaac ctatcttctt cgacacatgg gataacgagg
421 cttatgtgca cgatgcacct gtacgatcac tgaactgcac gctccgggac tcacagcaaa
481 aaagcttggt gatgtctggt ccatatgaac tgaaagctct ccacctccag ggacaggata
541 tggagcaaca agtggtgttc tccatgtcct ttgtacaagg agaagaaagt aatgacaaaa
601 tacctgtggc cttgggcctc aaggaaaaga atctgtacct gtcctgcgtg ttgaaagatg
661 ataagcccac tctacagctg gagagtgtag atcccaaaaa ttacccaaag aagaagatgg
721 aaaagcgatt tgtcttcaac aagatagaaa tcaataacaa gctggaattt gagtctgccc
781 agttccccaa ctggtacatc agcacctctc aagcagaaaa catgcccgtc ttcctgggag
841 ggaccaaagg cggccaggat ataactgact tcaccatgca atttgtgtct tcctaaagag
901 agctgtaccc agagagtcct gtgctgaatg tggactcaat ccctagggct ggcagaaagg
961 gaacagaaag gtttttgagt acggctatag cctggacttt cctgttgtct acaccaatgc
1021 ccaactgcct gccttagggt agtgctaaga ggatctcctg tccatcagcc aggacagtca
1081 gctctctcct ttcagggcca atccccagcc cttttgttga gccaggcctc tctcacctct
1141 cctactcact taaagcccgc ctgacagaaa ccacggccac atttggttct aagaaaccct
1201 ctgtcattcg ctcccacatt ctgatgagca accgcttccc tatttattta tttatttgtt
1261 tgtttgtttt attcattggt ctaatttatt caaagggggc aagaagtagc agtgtctgta
1321 aaagagccta gtttttaata gctatggaat caattcaatt tggactggtg tgctctcttt
1381 aaatcaagtc ctttaattaa gactgaaaat atataagctc agattattta aatgggaata
1441 tttataaatg agcaaatatc atactgttca atggttctga aataaacttc tctgaag
//