LOCUS HUMFCER 1530 bp mRNA linear HUM 08-NOV-1994
DEFINITION Human Fc-epsilon receptor (IgE receptor) mRNA, complete cds (H107
epitope).
ACCESSION M15059
VERSION M15059.1
KEYWORDS Fc-epsilon receptor; IgE receptor; cell surface receptor;
glycoprotein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1530)
AUTHORS Ikuta,K., Takami,M., Kim,C.W., Honjo,T., Miyoshi,T., Tagaya,Y.,
Kawabe,T. and Yodoi,J.
TITLE Human lymphocyte Fc receptor for IgE: sequence homology of its
cloned cDNA with animal lectins
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 84 (3), 819-823 (1987)
PUBMED 2949326
COMMENT Original source text: Human B-lymphoblastoid cell line RPMI 8866,
cDNA to mRNA, clone Fc-epsilon R-2.
Draft entry and printed copy of sequence [1] kindly provided by
J.Yodoi, 30-MAR-1987.
The peptide annotated below is the membrane-bound form of the
receptor. Possible cleavage sites of the Mb-bound receptor to
liberate the soluble form are after positions 654, 660 and 678.
FEATURES Location/Qualifiers
source 1..1530
/db_xref="H-InvDB:HIT000194373"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="1q21-q23"
gene 1..1530
/gene="CRPP1"
mRNA <1..1530
/gene="CRPP1"
/product="Fce mRNA"
CDS 214..1179
/gene="CRPP1"
/note="Fc-epsilon receptor old gene name 'FCE1A'"
/codon_start=1
/protein_id="AAA52434.1"
/db_xref="GDB:G00-119-072"
/translation="MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLL
WHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRL
KSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVC
NTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTG
SWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRK
LGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS"
BASE COUNT 352 a 461 c 436 g 281 t
ORIGIN 79 bp upstream of SalI site.
1 agtggctcta ctttcagaag aaagtgtctc tcttcctgct taaacctctg tctctgacgg
61 tccctgccaa tcgctctggt cgaccccaac acactaggag gacagacaca ggctccaaac
121 tccactaacc agagctgtga ttgtgcccgc tgagtggact gcgttgtcag ggagtgagtg
181 ctccatcatc gggagaatcc aagcaggacc gccatggagg aaggtcaata ttcagagatc
241 gaggagcttc ccaggaggcg gtgttgcagg cgtgggactc agatcgtgct gctggggctg
301 gtgaccgccg ctctgtgggc tgggctgctg actctgcttc tcctgtggca ctgggacacc
361 acacagagtc taaaacagct ggaagagagg gctgcccgga acgtctctca agtttccaag
421 aacttggaaa gccaccacgg tgaccagatg gcgcagaaat cccagtccac gcagatttca
481 caggaactgg aggaacttcg agctgaacag cagagattga aatctcagga cttggagctg
541 tcctggaacc tgaacgggct tcaagcagat ctgagcagct tcaagtccca ggaattgaac
601 gagaggaacg aagcttcaga tttgctggaa agactccggg aggaggtgac aaagctaagg
661 atggagttgc aggtgtccag cggctttgtg tgcaacacgt gccctgaaaa gtggatcaat
721 ttccaacgga agtgctacta cttcggcaag ggcaccaagc agtgggtcca cgcccggtat
781 gcctgtgacg acatggaagg gcagctggtc agcatccaca gcccggagga gcaggacttc
841 ctgaccaagc atgccagcca caccggctcc tggattggcc ttcggaactt ggacctgaag
901 ggagagttta tctgggtgga tgggagccat gtggactaca gcaactgggc tccaggggag
961 cccaccagcc ggagccaggg cgaggactgc gtgatgatgc ggggctccgg tcgctggaac
1021 gacgccttct gcgaccgtaa gctgggcgcc tgggtgtgcg accggctggc cacatgcacg
1081 ccgccagcca gcgaaggttc cgcggagtcc atgggacctg attcaagacc agaccctgac
1141 ggccgcctgc ccaccccctc tgcccctctc cactcttgag catggataca gccaggccca
1201 gagcaagacc ctgaagaccc ccaaccacgg cctaaaagcc tctttgtggc tgaaaggtcc
1261 ctgtgacatt ttctgccacc caaacggagg cagctgacac atctcccgct cctctatggc
1321 ccctgccttc ccaggagtac accccaacag caccctctcc agatgggagt gcccccaaca
1381 gcaccctctc cagatgagag tacaccccaa cagcaccctc tccagatgca gccccatctc
1441 ctcagcaccc caggacctga gtatccccag ctcaggtggt gagtcctcct gtccagcctg
1501 catcaataaa atggggcagt gatggcctcc
//