LOCUS HUMHLACFO 1413 bp mRNA linear HUM 08-NOV-1994
DEFINITION Human MHC class I HLA-C allele HLA-4, partial cds.
ACCESSION M11886
VERSION M11886.1
KEYWORDS cell surface glycoprotein; class I gene; integral membrane
glycoprotein; major histocompatibility complex.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1413)
AUTHORS Davidson,W.F., Kress,M., Khoury,G. and Jay,G.
TITLE Comparison of HLA class I gene sequences. Derivation of
locus-specific oligonucleotide probes specific for HLA-A, HLA-B,
and HLA-C genes
JOURNAL J. Biol. Chem. 260 (25), 13414-13423 (1985)
PUBMED 3863816
COMMENT Original source text: Homo sapiens liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1413
/db_xref="H-InvDB:HIT000194133"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="6p21.3"
/tissue_type="liver"
gene 1..1413
/gene="HLA-C"
mRNA <1..1413
/gene="HLA-C"
/product="HLA-4 transplantation antigen, mRNA"
CDS <1..1029
/gene="HLA-C"
/note="HLA-4 transplantation antigen"
/codon_start=1
/product="transplantation antigen"
/protein_id="AAA52665.1"
/db_xref="GDB:G00-119-311"
/translation="CSHSMRYFDTAVSRPGAGEPRFISVGYVDDTQFVRFDSDAASPR
GEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGCD
LGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAARAAEQLRAYL
EGLCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQ
RDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEP
SSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSD
ESLITCKA"
BASE COUNT 296 a 415 c 429 g 273 t
ORIGIN Chromosome 6p21.3.
1 tgctcccact ccatgaggta tttcgacacc gccgtgtccc ggcccggcgc cggagagccc
61 cgcttcatct cagtgggcta cgtggacgac acgcagttcg tgcggttcga cagcgacgcc
121 gcgagtccga gaggggagcc gcgggcgccg tgggtggagc aggaggggcc ggagtattgg
181 gaccgggaga cacagaagta caagcgccag gcacaggctg accgagtgag cctgcggaac
241 ctgcgcggct actacaacca gagcgaggac gggtctcaca ccctccagag gatgtctggc
301 tgcgacctgg ggcccgacgg gcgcctcctc cgcgggtatg accagtccgc ctacgacggc
361 aaggattaca tcgccctgaa cgaggacctg cgctcctgga ccgcggcgga caccgcggct
421 cagatcaccc agcgcaagtg ggaggcggcc cgtgcggcgg agcagctgag agcctacctg
481 gagggactgt gcgtggagtg gctccgcaga tacctggaga acgggaagga gacgctgcag
541 cgcgcagaac ccccaaagac acacgtgacc caccaccccc tctctgacca tgaggccacc
601 ctgaggtgct gggccctggg cttctaccct gcggagatca cactgacctg gcagcgggat
661 ggggaggacc agacccagga caccgagctt gtggagacca ggccagcagg agatggaacc
721 ttccagaagt gggcagctgt ggtggtgcct tctggacaag agcagagata cacgtgccat
781 atgcagcacg aggggctgca agagcccctc accctgagct gggagccatc ttcccagccc
841 accatcccca tcatgggcat cgttgctggc ctggctgtcc tggttgtcct agctgtcctt
901 ggagctgtgg tcaccgctat gatgtgtagg aggaagagct caggtggaaa aggagggagc
961 tgctctcagg ctgcgtgcag caacagtgcc cagggctctg atgagtctct catcacttgt
1021 aaagcctgag acagctgcct gtgtgggact gagatgcagg atttcttcac acctctcctt
1081 tgtgacttca agagcctctg gcatctcttt ctgcaaaggc acctgaatgt gtctgcgttc
1141 ctgttagcat aatgtgagga ggtggagaga cagcccaccc ccgtgtccac cgtgacccct
1201 gtccccacac tgacctgtgt tccctccccg atcatctttc ctgttccaga gaggtggggc
1261 tggatgtctc catctctgtc tcaaattcat ggtgcactga gctgcaactt cttacttccc
1321 taatgaagtt aagaacctga atataaattt gtgttctcaa atatttgcta tgaagcgttg
1381 atggattaat taaataagtc aattcctaaa aac
//