LOCUS LC315809 15401 bp DNA linear BCT 02-MAR-2018
DEFINITION Staphylococcus aureus genes for island SaPISaitama2, complete
sequence, strain: Saitama2.
ACCESSION LC315809
VERSION LC315809.1
KEYWORDS .
SOURCE Staphylococcus aureus
ORGANISM Staphylococcus aureus
Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
Staphylococcus.
REFERENCE 1 (bases 1 to 15401)
AUTHORS Uehara,Y., Sasaki,T., Baba,T., Furuichi,M., Kawada,M. and
Hiramatsu,K.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-2017) to the DDBJ/EMBL/GenBank databases.
Contact:Yuki Uehara
Juntendo University, Department of Infection Control Science;
2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan
REFERENCE 2
AUTHORS Uehara,Y., Sasaki,T., Baba,T., Furuichi,M., Kawada,M. and
Hiramatsu,K.
TITLE Regional epidemic of ST834 community-associated
methicillin-resistant Staphylococcus aureus among Japanese children
JOURNAL Unpublished (2017)
COMMENT
FEATURES Location/Qualifiers
source 1..15401
/collection_date="2011-08-20"
/country="Japan"
/db_xref="taxon:1280"
/host="Homo sapiens"
/isolation_source="skin"
/mol_type="genomic DNA"
/note="ST834 CA-MRSA"
/note="Staphylococcus aureus genomic island SaPISaitama2"
/organism="Staphylococcus aureus"
/strain="Saitama2"
repeat_region 1..15
/note="SaPISaitama2 attachment site"
/rpt_type=direct
CDS complement(128..1234)
/codon_start=1
/gene="int"
/product="integrase"
/protein_id="BBD13343.1"
/transl_table=11
/translation="MTHNLNLSHNIYKDTKRGTYYFRITYYDKSNTRKYITRKGFKQR
KDAVKKCNEMMDELEGVGHLNRLPFDKLVEEYIDWYSARRKTSSVKALKTHTNNHLLP
YFKSMDVFKMTTQDVMKFQNKKLKEGHSGEYLKKMHVYLVSLLNHAMKFHELKQNVAS
LVGNFEIESQKRLNYWTLEQFNQFYDALATQQQKLFFKLLFYSGARKGEIRALTWRDV
NFEDEFIHINKTDYHGEVTAPKTKSAIRDIYLPTHMMYDIKDYLIWYKENNIYKDDYV
LFGTFYKAYSESTIDRWFTNALKVLDEQLPNGQNFPRIVIHELRHSHASMLVNLGASV
MIIAQRLGHSDTTEVYNRYGHLYPSTQKEIVKYL"
CDS complement(1224..2027)
/codon_start=1
/product="transcriptional regulator, XRE family"
/protein_id="BBD13344.1"
/transl_table=11
/translation="MDKKTDIGLRIKSIRLAKGLNLREFGEEISKLTKEKKYISDSIV
SRWEKGVSIPNAKRLKAIAEYGNVSINFLLYGNEVSYEDIYQNIQSVNMKNNIQDKLI
DFIVNYMPSSEQNTYYFKVASLITIINDHTDSNIDCIIEQMYSFISNENMTFYHHGVY
LLLNEDFKKLPVQLYLTEFIYHLLIQISLKYPEVYFLNLLSQFDDLKNNIQEISTKHE
ILHNHTRRSKIAEFIDSKEYQKLMNKIDVMKEKLLNKNILKKQGDTHDT"
CDS 2163..2366
/codon_start=1
/product="transcriptional regulator"
/protein_id="BBD13345.1"
/transl_table=11
/translation="MNKVLGYRKMLNFTQQQMAKELKISEQSYRNKEKGKTEFKKEEM
LTFKNILISKGMTNITLDDIFFN"
CDS 2402..2620
/codon_start=1
/gene="xis"
/product="DNA-binding protein"
/protein_id="BBD13346.1"
/transl_table=11
/translation="MTKLAYPMLYITRKEKGDTQKKVASKLGISPQRYQLKESGKAIF
NLNECQILSEMYDMPIDELFSSKIKVGK"
CDS 2632..2778
/codon_start=1
/product="putative terminase"
/protein_id="BBD13347.1"
/transl_table=11
/translation="MKMYLTYICLVSLLTILLLAISNMYVAFSVYGMMATYGFNLTGG
LENE"
CDS 2771..2980
/codon_start=1
/product="hypothetical protein"
/protein_id="BBD13348.1"
/transl_table=11
/translation="MNNEQKEVIEHVVYQLELSIMNNFESYEHTEYVDGIEVVSEISR
EKHLELIMKWCAQELKNNFQLEKGE"
CDS 2983..3300
/codon_start=1
/product="hypothetical protein"
/protein_id="BBD13349.1"
/transl_table=11
/translation="MNWEIKDLMCDIEVIKEKINDVAIKHGWFVEDKFVKNELETKQE
HINFSASYLEHRIQNEHTVELLQVYLKEFGELIQKFHEIEKASSENFGEESDDAKKLK
ITE"
CDS 3367..4236
/codon_start=1
/gene="pri"
/product="primase C terminal 1"
/protein_id="BBD13350.1"
/transl_table=11
/translation="MNEIKLEYDTHVSVVHYESLDSRSFKSFSKPKWSKLINKLSVPI
EANYKYARGVAVYGDIKNGANDHGEIIKKHRNDVNVVYRDVIVLDYDEINDLKQLHEA
ISSALSNVAWFWHTSYSHRTEQARIRLYIPLNERISADDYRKYSKVLANKIGHKVDEG
SYQPSRCFALPVIQKGHIFIKRVNDCPIIDVDMLEQWSKELEQSNASPNVIGYTRRDS
AYWRELSFGTTEGNRNNALASLVGHLLRCRVNDYIVYSYALLWGQFACKPPMKEQEIN
ATFQSILNKHYNN"
CDS 4250..5950
/codon_start=1
/gene="rep"
/product="replication initiator"
/protein_id="BBD13351.1"
/transl_table=11
/translation="METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQL
IPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISD
SRQLLKLVNKKLDVTSSTSTKLVDYINVSKRYNPPLNVKVATRLGHVKGYFIYPYQEV
MKDSNIKLFSNDKGFQKLIDSFQSKGTLEGYSKKVFGQIKDLPMVMVMLYASLGSVLL
REFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFP
MFKDDTRNTHPKFVTSATYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMA
DEKAGVSARVVTLQDQPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFE
SYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNK
TIDKPKQLLEELLQYLDANRNNIAGDGYSSVKNGDIKAIYKRDYLCILGQTVYDKLGH
EMQTITGQWDKKGYLITSKDRIQKEVRFNSQKNRGYAIKDEIIKELGFDFSNSHNPYN
"
CDS 6280..6660
/codon_start=1
/product="hypothetical protein"
/protein_id="BBD13352.1"
/transl_table=11
/translation="MDKEQLKKYIYDYVKEYKEIPIYQLEDLFKELNHDYIGRTSITH
DKDENIVFWSGWNKITMFALIELVKSEQLDLVYRGSFVMRYLLDGRVPNLPLAICYPE
DGQQTDVPSWVPMVLRINKEEKIK"
CDS 6657..7298
/codon_start=1
/product="hypothetical protein"
/protein_id="BBD13353.1"
/transl_table=11
/translation="MNIETIVNQFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDM
VYVTMNGKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKQLSISD
MMASHLFEDEYFMYGLQTYAESNNSDVFEYLKNGFDTDTLEGIQSSNTDVIANIEMLY
QLATGINEPAPELVEGLRLVTEFVQDENATQEDYKALESKLNDLKESYYSLSK"
CDS 7747..8088
/codon_start=1
/product="hypothetical protein"
/protein_id="BBD13354.1"
/transl_table=11
/translation="MQSIAEKETYHLPTEHLQVFNVIKNTSNKYITKTKILNQLGYEY
NSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIITTEQEKQQAMRSIKKLADGSM
KRYEALKRIKV"
CDS 8100..8678
/codon_start=1
/product="hypothetical protein"
/protein_id="BBD13355.1"
/transl_table=11
/translation="MKTESYFKEYNQFVIDQQKAIQELEQERNALESKIKIDKSTYKQ
LIMDGQDDKADNLYQATDADEKKLKALNKRLETKKSVSKEVKYQKTIELLKHQSELSS
LYESEKQSALGKLKKVVDAYNEIIDEIEDINDRYEDEHQQYASIYSQEQLYDDKEARE
ALNGYFRENIFTSYINGNDLPYEHNNKLFLKR"
CDS 8696..8914
/codon_start=1
/product="hypothetical protein"
/protein_id="BBD13356.1"
/transl_table=11
/translation="METKYELNNTKKVANAFGLNEEDTNLLINAVDLDIKNNMQEISS
ELQQSEQSKQKQYGTTLQNLAKQNRIIK"
CDS 8965..9492
/codon_start=1
/product="hypothetical protein"
/protein_id="BBD13357.1"
/transl_table=11
/translation="MKLLKTKNCLYYRNGDNKLSEYQLLTQFNPAFINKKIKMCEFQI
ESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKAGLQNYKNRSINNMALLKKVL
NHYTEKEQKKVVKYMRSNGRYKPYNVIERLQVDLYQASIKQRSERQKQRNTAIENSKI
ARVNAYHQSSHVKVV"
CDS 9495..9836
/codon_start=1
/product="hypothetical protein"
/protein_id="BBD13358.1"
/transl_table=11
/translation="MDKKQIKDFVCDYHKRTKSDVLIDDEINTDEFFSIGDENSNKWM
ADDNIDDHIVKNHLEMIVDQVANDKEFYIFDSLIQGRSFKDISNVLECSEQSVILWYE
TLLDKIVEVIE"
CDS 9833..10402
/codon_start=1
/gene="ter"
/product="putative terminase"
/protein_id="BBD13359.1"
/transl_table=11
/translation="MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLK
KPHIKQYIQEQKDKVIDENVLTAKELLHVLTNAAVGDETETKEVVVKRGEYKENPQSG
KVQLVYNEHVELVEVPIKPSDRLKARDMLGKYHKLFTDKHDINGNLPIFINIGEWDGD
DEDLDKTVQEVSNTNPNHTVIVDDIPLED"
CDS complement(10557..11261)
/codon_start=1
/gene="tst"
/product="toxic shock syndrome toxin-1"
/protein_id="BBD13360.1"
/transl_table=11
/translation="MNKKLLMNFFIVSPLLLATIATDFTPVPLSSNQIIKTAKASTND
NIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGEKV
DLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYWPKFD
KKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTEK
PPINIDEIKTIEAEIN"
CDS complement(12138..12698)
/codon_start=1
/product="secreted protein Ear"
/protein_id="BBD13361.1"
/transl_table=11
/translation="MNKKLLTKTLIASALVLTTVGSGFHSSSNYNGINNVAKAEQTTD
NALWKNVRDALKDANIIDKTDNENVKVTYKIENGGENTIEGTANLENISTSNNPKINP
QNVTKINITRKNSNYPNIDANNTWKKLTEKLKEKNIVNNGDNVSILSTDPKDETVFGK
VGEDKSNVSNRYINPKDINEIQITKK"
CDS 13486..14286
/codon_start=1
/gene="sec"
/product="superantigen enterotoxin SEC"
/protein_id="BBD13362.1"
/transl_table=11
/translation="MYKRLFISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEF
TGTMGNMKYLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAK
KYKDEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLV
RVYENKRNTISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFNSSPYETGYIKFIEN
NGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEVHLTTKNG"
CDS complement(14454..15176)
/codon_start=1
/gene="sel"
/product="superantigen enterotoxin SEL"
/protein_id="BBD13363.1"
/transl_table=11
/translation="MKKRLLFVIVITLFIFSSNHTALSNGDVGPGNLRNFYTKYEYVN
LKNVKDKNSPESHRLEYSYKNDTLYAEFDNEYITNDLKGKNVDVFGISYKYGSNSRTI
YGGVTKAENNKLDSPRIIPINLIINGKHQTVTTKSVSTDKKMVTAQEIDVKLRKYLQD
EFNIYGHNDTGKGKEYGTSSKFYSGFDKGSVVFHMNDGSNFSYDLFYTGYGLPESFLK
IYKDNKTVDSTQFHLDVEISKR"
repeat_region 15387..15401
/note="SaPISaitama2 attachment site"
/rpt_type=direct
BASE COUNT 5630 a 2054 c 2675 g 5042 t
ORIGIN
1 tcccgccgtc tccattatat agtctgcgac cttagtggtt gtaggctttt tatttttgag
61 tgcacagata gtgcacagaa aatgcacagg atataaaaag acaccaccaa ttttagttgg
121 tagtgcctta taagtattta actatttctt tctgtgtact aggatataaa tgaccatatc
181 ggttatatac ttcagtcgta tcgctgtgac ctaaacgctg agctataatc attacactag
241 cccctagatt aactagcata gatgcatggc tatgtcttaa ctcgtgtata acgattctag
301 ggaaattttg tccgtttggt aattgctcat ccaacacttt taatgcgtta gtaaaccaac
361 gatcaatagt agactcgctg taagctttat agaatgtacc aaacaataca tagtcgtcct
421 tgtatatgtt attctcttta taccaaatta aataatcttt gatgtcatac atcatgtgag
481 taggcaaata tatatcacgt atggctgatt tcgttttagg ggctgtcact tcaccgtgat
541 agtccgtttt gtttatatgg ataaattcat cttcaaaatt aacgtcacgc catgtgagag
601 ctctaatttc gccctttctt gctccagagt agaacaatag tttgaaaaat aatttttgtt
661 gttgtgtagc aagcgcatca tagaattgat tgaattgttc taacgtccaa taattcaatc
721 gtttctgtga ttctatttca aaattcccta caagagatgc aacattttgt tttaactcat
781 gaaacttcat tgcatgattc agtaatgata ctaaatatac atgcatcttc tttaaatatt
841 ctccagaatg cccctctttt aacttcttat tctgaaattt catcacatct tgtgtagtca
901 ttttaaatac atccatagat ttaaaataag gtagcaaatg gttattggta tgtgtcttta
961 atgcttttac acttgatgtc tttcgacgtg ctgaatacca gtctatatat tcttcaacga
1021 gcttgtcaaa aggtaatcta ttaaggtgtc cgactccctc taattcgtcc atcatttcgt
1081 tacatttctt tactgcatct ttacgttgtt taaacccctt acgtgttatg tacttacgag
1141 tattgctctt gtcatagtaa gtgatacgga aataataagt accgcgttta gtgtctttat
1201 atatattatg ggatagattt aagttatgtg tcatgagtat cgccttgttt ttttaaaata
1261 tttttattga gtaacttttc tttcataaca tcgattttat tcattaattt ttggtattct
1321 ttagagtcta taaattctgc tattttactt cttctagtat gattgtgtaa tatttcatgc
1381 ttagttgaaa tttcttgtat attatttttg aggtcgtcaa attgcgacaa caagtttaaa
1441 aagtagactt caggatattt taatgaaatt tggattaata aatgataaat aaattcagtg
1501 agatataatt gtacaggtaa ttttttgaaa tcttcgttta gcaataaata aacaccgtga
1561 tggtaaaatg tcatgttctc atttgagatg aatgaataca tttgttctat tatacaatct
1621 atatttgaat ctgtatgatc attaataatt gtaattaaac tagctacttt aaaataataa
1681 gtattttgct cactagaggg catataatta acgataaaat caattaactt gtcttgaata
1741 ttgtttttca tattcactga ttgtatgttt tgataaatat cttcgtatga aacctcattt
1801 ccatatagta aaaaattaat agacacatta ccatattctg caatagcttt taaccttttg
1861 gcattgggta ttgacacccc tttttcccat cgactaacta tactatccga aatatatttt
1921 ttttcttttg ttaattttga tatttcttcg ccaaattctc ttaaattcaa tcctttagca
1981 agtctgatac ttttgatgcg taaaccaata tctgtttttt tatccatatt ttcacttcct
2041 atctaatgag aatatccata aaaactttcg taaaccgacg tttttgtgtt gcttttagtt
2101 ttcgtgtctg ttatattata catacagacg agaacttacg tctagggaag aggtgataat
2161 aagtgaataa agtactgggt tataggaaaa tgttgaactt cacacaacaa caaatggcaa
2221 aagagcttaa aatatcagaa cagtcataca gaaataaaga aaaaggaaaa acggaattta
2281 agaaagaaga aatgttaact tttaaaaaca tacttatttc aaagggaatg accaatataa
2341 ctttagatga tatttttttt aattaaaatc cgacgtaaaa ctacgtaaaa gaggtggtca
2401 aatgacaaaa ctagcttatc caatgttata cattactaga aaagaaaagg gtgacacaca
2461 aaagaaagtt gctagcaaac ttggtattag tccacaacgc taccagttaa aggaaagtgg
2521 caaggcaata tttaatttaa atgagtgtca gattctttca gaaatgtatg atatgccaat
2581 tgatgagttg ttttcatcaa aaattaaagt aggaaaatag gaggcaaggc aatgaaaatg
2641 tacttaactt atatttgctt agtttcattg ttaacaattt tattactagc aatatctaac
2701 atgtatgtcg cttttagtgt gtacggcatg atggcaactt atggatttaa tttaacagga
2761 ggattagaaa atgaataatg aacaaaaaga agtaatagaa cacgtggttt atcaacttga
2821 gttaagtatc atgaataatt ttgaaagtta tgaacacacg gaatatgttg atggtattga
2881 agtggtttca gagatcagtc gtgaaaagca cttagaattg ataatgaaat ggtgcgcaca
2941 agaattaaag aataattttc aattagaaaa aggagaataa atatgaattg ggaaattaaa
3001 gatttgatgt gtgatattga agtgataaaa gaaaaaatca atgatgtagc tatcaaacat
3061 ggttggtttg ttgaagataa atttgtcaaa aatgaattag aaacaaaaca ggaacatatt
3121 aatttttctg ctagctattt agaacatcgt atacaaaatg aacatacagt tgagttatta
3181 caggtgtact taaaagaatt cggtgaactt atacaaaagt ttcatgaaat agaaaaagca
3241 tcatctgaga actttggcga ggaatcagat gacgcaaaga aattaaaaat tacagagtaa
3301 ttaataaaaa ataactattt ttattataac atctttgctc tgttgtttca ttaagaggta
3361 caaaaaatga atgaaattaa attagaatat gacacacatg tttcagtggt acattatgaa
3421 agtttagact cacgttcatt taagagcttt tcaaaaccta aatggagtaa gttaattaat
3481 aaactgtctg tgcctataga agcaaattat aagtatgcac gtggtgttgc tgtttacggt
3541 gatattaaaa acggtgcaaa tgatcatggt gaaattatca aaaagcatcg caatgacgtt
3601 aatgtcgtat acagagatgt gattgtactt gattacgatg aaataaatga tttaaagcaa
3661 ttacatgaag caatcagctc agctttaagc aatgttgcat ggttttggca cacaagttac
3721 tcgcacagaa ctgaacaagc tagaatacgc ctgtatatcc ctctaaatga gcgaataagt
3781 gcagatgatt atcgtaaata ttcaaaggta ttagcaaaca aaattggtca taaagttgat
3841 gaaggttcat atcagccaag tagatgtttt gcattaccag ttattcaaaa agggcacata
3901 tttattaagc gagtgaatga ctgtccaatt atcgatgttg atatgctcga acagtggtcg
3961 aaggaacttg aacaatcaaa tgctagtcct aatgttatag ggtacacgcg acgtgatagt
4021 gcgtactggc gtgagttaag ctttggaaca actgaaggca atcgtaacaa tgcactagct
4081 agcttagtgg ggcatttatt aagatgtcgc gttaatgatt atattgtgta ttcatatgct
4141 ttattatggg ggcaattcgc atgtaaacca cctatgaaag aacaagaaat caacgcaact
4201 tttcaatcga tattaaataa acactataac aattagaaag gggctttgta tggaaacagg
4261 taaaagtgat gtacttgata aaattgaaaa aattaataaa aaagatagtg ccttacaaga
4321 aattataccg aaaggctatg aaattgaaca tcatcaatgc ggtgttgctt tatatcaact
4381 tataccaagt aaaaaagaag gcgaaccaga taaaaaggtt tttatcacaa atacaatccc
4441 tcaaattact gaacgctttg aagatattga gagtaacgaa gtcagcttta atatgctttt
4501 ctatgacaat aaaacgcctg taaatatagc agtgagcgcc gaagaaattt cagatagtcg
4561 tcaactcttg aaattggtta ataaaaagct agatgtaaca tcgtcgacat ctactaaact
4621 tgttgactat attaatgtat ctaaacggta taatccacca ttaaatgtta aagttgcaac
4681 gcgcttggga catgtgaaag gttattttat ttatccttat caagaagtga tgaaagacag
4741 caatatcaag ttgtttagta atgataaagg atttcaaaag ttaatagact cttttcaaag
4801 caaaggaaca ttagaaggtt actctaaaaa agtgttcggt caaataaaag atctaccaat
4861 ggtaatggtt atgttatatg catctttagg ctcagtttta ttaagagaat ttggattaca
4921 accctttatt gtagaaatat caggtagtac atccacaggt aaaacattca cactcaactt
4981 agtatcaagt gtttggggaa ccagtgacct tattacgaca tggagttcta ctcaaaatag
5041 tattgaatca atggcatcat ttttgaactc atttccaatg tttaaagatg atacacgtaa
5101 tacacatcct aagtttgtta ccagtgccac atataacttt tctagtggcg aaagcaaatc
5161 aagaagtaat attaatttaa cgctaaatgc taaaaaagaa tggcgaaata ttttaatttc
5221 tactggtgaa tcatctatcg caaatatggc tgatgaaaaa gcgggtgtat cagcacgtgt
5281 agttacacta caagatcaac catatccaga taattttgat tttaccacat tagacaaatc
5341 gtttagggag aactatggaa cgttagggtt ggcatttatt aaacaatatg agtctaaaaa
5401 agacgtgtat aagaacgctt ttgaaagcta tcaacggtat tttaatcaaa aaggtagtaa
5461 tgaaatcatg caacgtttag gacgtgcctt tgcgttacta caagttaccg gtgaggtttt
5521 gaatgatatt gatggatttg aacatgacca ttttaaaatt attgaacaag cctatgacag
5581 catggttaaa aacaataaga caattgataa acctaagcaa ctgttagagg aactattaca
5641 atatttagat gcaaatagaa ataatatcgc tggtgatggc tatagttcag tcaaaaatgg
5701 tgacatcaaa gctatatata aacgtgatta tttatgtata ttaggtcaaa ctgtatacga
5761 caagttaggt catgaaatgc aaactatcac aggacaatgg gacaaaaagg gttatttaat
5821 aactagtaaa gacagaatac aaaaagaagt tagatttaac tctcaaaaga atagagggta
5881 tgccattaaa gatgagatta taaaagaatt agggtttgat ttttctaatt cacataatcc
5941 atataattaa aaaagtcccc aaagtctcca aacagtcccc actaaaaagg aatgattggg
6001 gacttaataa acactattac cgcaatactt tagagagatt agtccccaaa gtccccaata
6061 aaaaacagtg tttatataaa atgatcaaaa agaacattga gtgtaattta atatatagct
6121 accatcgttt ataaatatgg tgactatggg gactatttct aacaaaatca gttatatcaa
6181 cgggtgaaac agtccccaat aaataattag ggtggggact cactggggac tagtccccta
6241 ctaaaataaa aaacatcaaa ttaatgctgg aggttacaca tggataaaga acaacttaaa
6301 aagtatatat acgattatgt aaaagaatat aaggagatac cgatatatca gttagaagat
6361 ttgtttaaag aactgaatca cgactatata gggagaacta gtatcacaca cgataaggat
6421 gagaatattg tgttttggag tggatggaac aaaattacaa tgtttgcgtt gattgaatta
6481 gttaaaagtg aacaacttga tttagtgtat agaggtagtt ttgtaatgcg ttatttgttg
6541 gatggtagag ttcctaattt accattagct atttgttatc cagaagatgg acaacaaact
6601 gacgtgccct catgggtgcc tatggtatta agaataaata aagaggagaa aatcaaatga
6661 acatagaaac tatcgtaaac caatttgaaa cacgagcagg cacgttacta aggtactaca
6721 caggattatt agaacatagt aaagtgcaac catgttgctt taagttatac aatgatccat
6781 ttgatatggt ttatgtgacg atgaatggga agttattcgg tcatgtatat attaaagatt
6841 gtaaagtaag gcaatcattt gaattagcgt cacctaagca cactgagggg cttataagaa
6901 gcatagaagg tcattatgta ggttatgaat tacatgatgg caaacagctt tctattagtg
6961 atatgatggc tagtcatttg tttgaagatg agtattttat gtatggatta caaacatatg
7021 cagaatcaaa taatagtgat gtgtttgaat acctaaaaaa tggatttgat accgatacac
7081 ttgagggcat tcaatcgagt aatactgatg tgatagcaaa tattgaaatg ttgtatcagt
7141 tagctacggg aatcaatgaa ccagcaccag agttagttga ggggttgaga ttagtaactg
7201 agtttgtaca agatgagaat gcgacacaag aggattacaa ggctttagaa agtaaattga
7261 atgatctaaa agagtcttac tatagcttga gtaaataatg ttatgagggg tcacatgtag
7321 tgtgtggctc ctaataaaat actacgattt tatacgaggt atagcagttt aaaatggtaa
7381 ggttttcgga aggtgttggc ttttaaaatc ggaaggtata cagtctttga gaattgaaaa
7441 aatggcaaga tttgtgcaag gtgtgcgaac tttgttaacg ctaatacaag ctaaagtttg
7501 tgtttttggc ataggcctaa aagttaagtt tgttcgctgt ttgttcgtgt tactttaccg
7561 aacttaagtt ctatattagg ttaatgtgaa aagcctaacg ttaagtttat aacataattt
7621 tataagtgtt atatatgata agctaaacaa ttgataaacg cgctataaag cgaacgtaag
7681 tttgttttag acctgtaaaa atggtataat ttaggtatga aataattaaa agaaagaggt
7741 gtagaaatgc aaagtatcgc agaaaaagag acgtatcatt tacccaccga acacctgcaa
7801 gttttcaatg tgataaaaaa tacgtccaat aagtatatta ctaaaactaa aatcttaaat
7861 caattgggat atgaatataa ttcaagcaat gaacgatggt tacgaagagt aatcaattca
7921 ttagtatatg attatggcta tcctatcgga tgcagttata aacctagtga acgtggttat
7981 tacatcatta cgacagaaca agaaaagcaa caagcgatga gaagtattaa gaaattagct
8041 gatggcagta tgaaacgcta tgaagctttg aaacgaatta aagtgtaaag gggataaaaa
8101 tgaaaactga atcgtacttt aaagaataca accaatttgt aatagatcaa caaaaggcta
8161 tacaagaatt ggaacaagag cgtaatgcat tggagagtaa aataaagata gataagtcca
8221 catataaaca gttaatcatg gatggacaag atgataaagc agataaccta tatcaagcaa
8281 cagatgctga tgaaaagaaa ctaaaagcac ttaataaacg cttagagaca aagaaaagtg
8341 tgtcgaaaga agttaaatat caaaagacaa ttgaattatt aaaacatcaa agcgagttgt
8401 catcattata cgaatcagaa aagcaatcag ctttaggtaa attaaaaaaa gtagtcgatg
8461 catataatga gatcattgat gaaatagaag atattaatga tagatatgaa gatgagcatc
8521 agcaatatgc gagtatttat agtcaagaac aattatatga tgataaagag gctagggaag
8581 cattgaatgg ctactttaga gaaaatatat ttacatcata tattaatggt aatgatttgc
8641 catacgaaca caataacaag ttgtttttaa aacgttaaaa agaaagggta attaaatgga
8701 aacaaaatac gagttaaata atactaaaaa ggtcgcaaat gcatttggtt taaatgaaga
8761 agatacaaat ctattaataa atgcagttga tttggatatt aaaaacaata tgcaggagat
8821 ttcaagtgag ttacaacaat cagaacagtc taagcaaaag caatatggta caacgctaca
8881 aaatttagct aagcaaaaca ggattattaa atagcaatga ttgcctatcc aattcgggta
8941 ggctctgttt ataggggtga ataaatgaaa ctgcttaaaa cgaagaattg tttatattat
9001 cgtaatggcg acaataaact atctgagtat caactattaa cgcaatttaa cccagcattt
9061 attaataaaa aaattaagat gtgtgaattc caaattgaaa gtatgtacca tatgagtgcg
9121 tcgaccacaa catgtgatga aataatgggg gtcgtgtctg tctcatatcc gattgaaaaa
9181 ttagttatca aaattattga aacaaaagca gggttacaaa actataaaaa tagatctata
9241 aataatatgg cgttgttgaa aaaggtacta aatcattata cagaaaaaga gcagaagaaa
9301 gttgtaaaat atatgcgttc aaatggacga tataagccct acaacgtcat tgaacgttta
9361 caggttgatt tgtatcaagc aagtattaaa caacgttcag aacgtcaaaa acaaagaaat
9421 acagcaattg aaaatagcaa gattgcacga gtaaatgctt atcatcaatc ttcacatgta
9481 aaagtggtgt aacaatggat aaaaagcaaa taaaagactt cgtttgtgat tatcataagc
9541 gaactaaaag tgatgtgttg atagatgatg aaataaatac cgatgaattc ttttcaatag
9601 gtgatgaaaa ttctaataaa tggatggcag acgataacat tgatgatcat attgtaaaga
9661 atcacttaga aatgattgtt gaccaagtag ctaatgataa agagttttat attttcgatt
9721 ctttaataca aggacgtagt tttaaagata ttagcaatgt cttagagtgt tcagaacaat
9781 ctgtaatatt atggtatgaa accttattag ataaaattgt ggaggtgata gaatgagtga
9841 gttaacggca aaacaagcgc gttttgtgaa tgagtatata agaacactta atgtaacaca
9901 aagtgccata aaagcaggct atagcgcaaa tagtgcacat gtgacaggat gtaggttatt
9961 aaagaagcca cacatcaagc aatatataca agaacaaaaa gataaggtta tagatgagaa
10021 tgtattaacc gcaaaagagt tactacatgt gcttacgaat gcggcagtcg gtgatgaaac
10081 agaaacgaaa gaagttgtgg tcaaacgtgg agaatataaa gagaatccac aaagtggcaa
10141 agtacagtta gtctataacg aacatgttga actggtagag gtgccaatta agccaagtga
10201 tcgtttaaaa gctcgtgata tgttgggtaa ataccataag ttatttacag ataagcatga
10261 tattaacggg aatttgccta tattcattaa tattggtgaa tgggatggcg atgatgaaga
10321 tttagataag acggtacaag aggtatctaa cactaatcct aatcatactg tgattgtgga
10381 tgatataccg ttagaggatt gattacagta aaaacgatta tcatattgag ttagtgagga
10441 ttagtttact aattcaccct agctttatat taaagcgtta taaagataaa agggagaacg
10501 cttattataa ttaacggact ccctttatta ataattatta cagaaaaagt ggtaaattaa
10561 ttaatttctg cttctatagt ttttatttca tcaatattta taggtggttt ttcagtattg
10621 tattcaaact ttttagataa atcactttga tatgtggatc cgtcattcat tgttattttc
10681 caataaccac ccgttttatc gcttgaacga tataatccat gtatttgagt tagctgatga
10741 cgaatttcaa agtctaaagt tgatatagct aattgttttt tatcgaactt tggccaatac
10801 tttaaggggc tatctttacc atgaacctta acttttaaag gtagttctat tggagtaggt
10861 aatttttcag tatttgtaac gccacttatt tggaaatgga tataagttcc ttcgctagta
10921 tgttggcttt ttttagttct ttttgtgttt aagtcaactt tttccccttt tgtaaaagca
10981 gggctataat aaggactcgg aaaaattata aggctgatgc tgccatctgt gttttttata
11041 cgcatagatc ctaaggaatt atctaaaact tcactatttg taaaagtgtc agacccacta
11101 ctataccagt ctagcaaatc ctttatatta tcgtttgtag atgcttttgc agttttgatt
11161 atttgattag atgataaggg aacaggggta aaatctgtag cgattgtcgc aagcaacaaa
11221 gggcttacga taaaaaaatt cattagtaat tttttattca tttttaattc tccttcattc
11281 aaatgtgtaa acgtttacat atagaatgta taaatattat ttaaatgaat caattaacca
11341 tctctaaatt attgtttaaa tatatattaa ttaaaaagtg tttgttacat agggagctat
11401 atcaaaaaaa tatagattta aacaaaattt taaagttaca aatagcaaaa aacaaagtgt
11461 gagtggtcat ttaaagaata ttaattaata taagtttgaa ttagttatat tctttaaagt
11521 cactttctag tggcgttttt tacgctgaga aacgtcctgt gttgcagtaa gggataatat
11581 tgtgtaacta gatatgttta tcgtaaatgt ggatccgtga aatatgactt taaacatcgc
11641 tggtcaatct atctttgaga ttggccgtag attaaaacca tatgaaacaa aatgacttag
11701 tggatgggga atttaggcta tggcttgaaa attggattaa gcaaattatc agataataga
11761 tttatgaaaa tagctgaaaa tccagaatta aatgtcctac cattggaata tatgggcgca
11821 tgtattttat actaattagc aacattaccg caagaagaga aaggataaga gtatttcact
11881 aaaggtgaga agtaaaaaaa caattgatat gactaggaga gaattagaat accttaaaaa
11941 ggaattgaaa caacgcgatg aaaaaacgcc caactccaat cacaaatgaa aaagcacaac
12001 tttttgagga gatagagaga aagtaattaa aggaagttaa aggtaaagaa tctgaagtaa
12061 ttgagtgtta catagatcca gaagattatc actgttcaaa agaaaagagg caggagtaat
12121 ctgcctctcg aaaaaagtta ttttttagtg atttgaattt catttatatc tttaggattg
12181 atgtatctat tgcttacgtt tgatttatct tctcctactt taccgaatac agtctcatct
12241 ttagggtctg tacttaagat tgaaacattg tcgccgttgt tcactatatt tttttctttc
12301 aatttttctg ttaatttttt ccatgtatta ttagcatcaa tattaggata gttcgaattt
12361 tttctagtta tattaatttt tgtaacattt tgagggttta ttttaggatt gtttgaagta
12421 ctaatatttt ctaaattagc tgttccttct atggtatttt ctccaccatt ttctatttta
12481 tacgtaacct tgacattttc attatctgtt ttatcgataa tattcgcgtc ttttaaagcg
12541 tctcttacat ttttccacaa tgcgttatct gtcgtttgct cagcttttgc aacgttatta
12601 ataccattat aatttgaaga agaatgaaaa cctgaaccta ctgttgttaa aactaaagca
12661 cttgctatca atgtttttgt taatagtttt ttattcattt tattttctcc tataacttat
12721 ttgcaatcaa ttacaaagta attttacaat tattatttat gtaaatcaat taaataatta
12781 ttaacaaatc cataaaattt tatcattaaa atataataat tttgagctag aagtattcgt
12841 catttatgct ataatcattt tagacacagc aatgtgttca aattttcatc tattcgtaag
12901 ttagccttcg ggctgacttt ttatttccat tattattcac atgttaatct tgttgatatt
12961 taggcaagta cttcggtact tgcctattat tatatctcta tacgatagga atcgactata
13021 tgacttacta agttttatag caaaataggc aattaacgca tatggcattt aacattgagt
13081 tgttatagta gttgtataat atatagctag ttccttataa cagcaaaaaa ataattttga
13141 ctataagatt aaatatatga atataaaatt aacagtagaa accaatttta gaatttgcaa
13201 aaatgaatgc attaattata aaagtgtgaa tatataaaca atgttattaa ttcaagatgc
13261 ttagaaatcc tctgtttttc ctagagaaag agttttgtat ataagttcaa atgaaatata
13321 gttaattaat tttcaaagca taacttaatt cctataaata aagagaaatc attaaatata
13381 attaattttc ttttaatatt tttttaattg aatatttaag aatataacat atatttaaag
13441 tgtatctaga tactttttgg gaatgttgga taaaggagat aaaaaatgta taagagatta
13501 tttatttcac gtgtaatttt gatattcgca ctgatactag ttatttctac acccaacgtt
13561 ttagcagaga gtcaaccaga ccctatgcca gatgatttgc acaaatcaag tgagtttact
13621 ggtacgatgg gtaatatgaa atatttatat gatgatcatt atgtatcagc aactaaagtt
13681 aagtctgtag ataaattttt ggcacatgat ttaatttata acattagtga taaaaaactg
13741 aaaaattatg acaaagtgaa aacagagtta ttaaatgaag atttagcaaa gaagtacaaa
13801 gatgaagtag ttgatgtgta tggatcaaat tactatgtaa actgctattt ttcatccaaa
13861 gataatgtag gtaaagttac aggtggtaaa acttgtatgt atggaggaat aacaaaacat
13921 gaaggaaacc actttgataa tgggaactta caaaatgtac ttgtaagagt ttatgaaaat
13981 aaaagaaaca caatttcttt tgaagtgcaa actgataaga aaagtgtaac agctcaagaa
14041 ctagacataa aagctaggaa ttttttaatt aataaaaaaa atttgtatga gtttaacagt
14101 tcaccatatg aaacaggata tataaaattt attgaaaata acggcaatac tttttggtat
14161 gatatgatgc ctgcaccagg cgataagttt gaccaatcta aatatttaat gatgtacaac
14221 gacaataaaa cggttgattc taaaagtgtg aagatagaag tccaccttac aacaaagaat
14281 ggataatgtt aatccgattt tgatataaaa agtgaaagta ttagatatat ttgaaaggta
14341 agtacttcgg tgcttgcctt tttaggatgc atatatatag attaaaccgc acttctatat
14401 taatagaaag tgcggttatt tatacagtgt aatctaaact ataataattg gaatcatctt
14461 tttgaaattt cgacatctag atgaaattgt gttgaatcaa cagttttatt atctttgtaa
14521 atttttaaga agctttctgg aagaccgtat cctgtgtaaa ataaatcata cgagaaatta
14581 gaaccatcat tcatatggaa tactacactc cccttatcaa aaccgctata aaattttgaa
14641 gaagtgccgt attctttacc tttaccagta tcattgtgtc cataaatatt aaattcatct
14701 tgcaagtatt ttcttagttt gacatctatt tcttgtgcgg taaccatttt tttatctgta
14761 gaaacacttt tagttgtaac tgtttgatgc ttgccattga taattaaatt tataggtatt
14821 attcttggcg aatctaattt attgttttct gctttagtaa caccaccata tatagtacga
14881 gagttagaac catatttata gcttatacca aaaacatcga cattttttcc ctttagatca
14941 ttagttatat attcattgtc aaattcagca tacaatgtat catttttata cgagtattct
15001 aagcggtgtg attctggtga atttttgtct ttaacattct ttaaattcac atattcatat
15061 ttagtataaa aatttcttag gtttcctgga cctacatcgc cgttagataa ggctgtatga
15121 ttagaagaaa aaataaataa agtaataaca attacaaata ataatctttt tttcatatta
15181 ggcacttcct tttcattata tttataataa cattataaat ataagttgaa taataaattt
15241 tagaaaattc ataaaaaata caaaaggtta taaaggaaga gttatagaaa aatatgtatc
15301 atcccacacg ttgcaggcag tgaatacgta tttgaatacg ttaattatga ggtgatgttg
15361 ggtgcacaaa tttatatagt tttatctccc gccgtctcca t
//