LOCUS HUMSUR1RNA 4892 bp mRNA linear HUM 11-JUN-1996
DEFINITION Homo sapiens sulfonylurea receptor (SUR1) mRNA, complete cds.
ACCESSION L78207
VERSION L78207.1
KEYWORDS membrane protein; potassium ion channel; sulfonylurea receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4892)
AUTHORS Gonzalez,G., Aguilar-Bryan,L. and Bryan,J.
TITLE Human beta cell sulfonylurea receptor, SUR1, expression
JOURNAL Unpublished
COMMENT On Jun 12, 1996 this sequence version replaced gi:1369843.
Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..4892
/db_xref="H-InvDB:HIT000194053"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="beta cell"
gene 1..4892
/gene="SUR1"
5'UTR <1..38
/gene="SUR1"
CDS 39..4784
/gene="SUR1"
/experiment="experimental evidence, no additional details
recorded"
/note="homologous to ciusur and ratsur"
/codon_start=1
/product="sulfonylurea receptor"
/protein_id="AAB02278.1"
/translation="MPLAFCGSENHSAAYRVDQGVLNNGCFVDVLNVVPHVFLLFITF
PILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESH
HLHLYMPAGMAFMAAVTSVVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDH
AIAFSQVRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFL
QPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRK
DIQGTQGARAIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENDVF
QPKTQFLGVYFVSSQEFLANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQ
TKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVI
LLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRTTLEYSNERLKQTNEMLRGIKL
LKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVSFF
KEADFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQC
APHEPTPQGPASKYQAVPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIM
GGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWS
SLPDSEIGEDPSPERETATDLDIRKRGPVAYASQKPWLLNATVEENIIFESPFNKQRY
KMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPF
SALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLK
DFQRSECQLFEHWKTLMNRQDQELEKETVTERKATEPPQGLSRAMSSRDGLLQDEEEE
EEEAAESEEDDNLSSMLHQRAEIPWRACAKYLSSAGILLLSLLVFSQLLKHMVLVAID
YWLAKWTDSALTLTPAARNCSLSQECTLDQTVYAMVFTAVCSLGIVLCLVTSVTVEWT
GLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRST
LLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFA
ETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIA
AVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKT
EAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALISPGQKIGICG
RTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIR
FNLDPERKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARA
FVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLK
RGAILEFDKPEKLLSRKDSVFASFVRADK"
3'UTR 4785..>4892
/gene="SUR1"
regulatory 4866..4871
/regulatory_class="polyA_signal_sequence"
/gene="SUR1"
BASE COUNT 1042 a 1525 c 1288 g 1037 t
ORIGIN
1 gccagctgag cccgagccca gaccgcgccc gcgccgccat gcccctggcc ttctgcggca
61 gcgagaacca ctcggccgcc taccgggtgg accagggggt cctcaacaac ggctgctttg
121 tggacgtcct caacgtggtg ccgcacgtct tcctactctt catcaccttc cccatcctct
181 tcattggatg gggaagtcag agctccaagg tgcacatcca ccacagcaca tggcttcatt
241 tccctgggca caacctgcgg tggatcctga ccttcatgct gctcttcgtc ctggtgtgtg
301 agattgcaga gggcatcctg tctgatgggg tgaccgaatc ccaccatctg cacctgtaca
361 tgccagccgg gatggcgttc atggctgctg tcacctccgt ggtctactat cacaacatcg
421 agacttccaa cttccccaag ctgctaattg ccctgctggt gtattggacc ctggccttca
481 tcaccaagac catcaagttt gtcaagttct tggaccacgc catcgcgttc tcgcaggtac
541 gcttctgcct cacagggctg ctggtgatcc tctatgggat gctgctcctc gtggaggtca
601 atgtcatcag ggtgaggaga tacatcttct tcaagacacc gagggaggtg aagcctcccg
661 aggacctgca agacctgggg gtacgcttcc tgcagccctt cgtgaatctg ctgtccaaag
721 gcacctactg gtggatgaac gccttcatca agactgccca caagaagccc atcgacttgc
781 gagccatcgg gaagctgccc atcgccatga gggccctcac caactaccaa cggctctgcg
841 aggcctttga cgcccaggtg cggaaggaca ttcagggcac tcaaggtgcc cgggccatct
901 ggcaggcact cagccatgcc ttcgggaggc gcctggtcct cagcagcact ttccgcatct
961 tggccgacct gctgggcttc gccgggccac tgtgcatctt tgggatcgtg gaccaccttg
1021 ggaaggagaa cgacgtcttc cagcccaaga cacaatttct cggggtttac tttgtctcat
1081 cccaagagtt ccttgccaat gcctacgtct tagctgtgct tctgttcctt gccctcctac
1141 tgcaaaggac atttctgcaa gcatcctact atgtggccat tgaaactgga attaacttga
1201 gaggagcaat acagaccaag atttacaata aaattatgca cctgtccacc tccaacctgt
1261 ccatgggaga aatgactgct ggacagatct gtaatctggt tgccatcgac accaatcagc
1321 tcatgtggtt tttcttcttg tgcccaaacc tctgggctat gccagtacag atcattgtgg
1381 gtgtgattct cctctactac atactcggag tcagtgcctt aattggagca gctgtcatca
1441 ttctactggc tcctgtccag tacttcgtgg ccaccaagct gtctcaggcc cagcggacga
1501 cactggagta ttccaatgag cggctgaagc agaccaacga gatgctccgc ggcatcaagc
1561 tgctgaagct gtacgcctgg gagaacatct tccgcacgcg ggtggagacg acccgcagga
1621 aggagatgac cagcctcagg gcctttgcca tctatacctc catctccatt ttcatgaaca
1681 cggccatccc cattgcagct gtcctcataa ctttcgtggg ccatgtcagc ttcttcaaag
1741 aggccgactt ctcgccctcc gtggcctttg cctccctctc cctcttccat atcttggtca
1801 caccgctgtt cctgctgtcc agtgtggtcc gatctaccgt caaagctcta gtgagcgtgc
1861 aaaagctaag cgagttcctg tccagtgcag agatccgtga ggagcagtgt gccccccatg
1921 agcccacacc tcagggccca gccagcaagt accaggcggt gcccctcagg gttgtgaacc
1981 gcaagcgtcc agcccgggag gattgtcggg gcctcaccgg cccactgcag agcctggtcc
2041 ccagtgcaga tggcgatgct gacaactgct gtgtccagat catgggaggc tacttcacgt
2101 ggaccccaga tggaatcccc acactgtcca acatcaccat tcgtatcccc cgaggccagc
2161 tgactatgat cgtggggcag gtgggctgcg gcaagtcctc gctccttcta gccgcactgg
2221 gggagatgca gaaggtctca ggggctgtct tctggagcag ccttcctgac agcgagatag
2281 gagaggaccc cagcccagag cgggagacag cgaccgactt ggatatcagg aagagaggcc
2341 ccgtggccta tgcttcgcag aaaccatggc tgctaaatgc cactgtggag gagaacatca
2401 tctttgagag tcccttcaac aaacaacggt acaagatggt cattgaagcc tgctctctgc
2461 agccagacat cgacatcctg ccccatggag accagaccca gattggggaa cggggcatca
2521 acctgtctgg tggtcaacgc cagcgaatca gtgtggcccg agccctctac cagcacgcca
2581 acgttgtctt cttggatgac cccttctcag ctctggatat ccatctgagt gaccacttaa
2641 tgcaggccgg catccttgag ctgctccggg acgacaagag gacagtggtc ttagtgaccc
2701 acaagctaca gtacctgccc catgcagact ggatcattgc catgaaggat ggcaccatcc
2761 agagggaggg taccctcaag gacttccaga ggtctgaatg ccagctcttt gagcactgga
2821 agaccctcat gaaccgacag gaccaagagc tggagaagga gactgtcaca gagagaaaag
2881 ccacagagcc accccagggc ctatctcgtg ccatgtcctc gagggatggc cttctgcagg
2941 atgaggaaga ggaggaagag gaggcagctg agagcgagga ggatgacaac ctgtcgtcca
3001 tgctgcacca gcgtgctgag atcccatggc gagcctgcgc caagtacctg tcctccgccg
3061 gcatcctgct cctgtcgttg ctggtcttct cacagctgct caagcacatg gtcctggtgg
3121 ccatcgacta ctggctggcc aagtggaccg acagcgccct gaccctgacc cctgcagcca
3181 ggaactgctc cctcagccag gagtgcaccc tcgaccagac tgtctatgcc atggtgttca
3241 cggctgtctg cagcctgggc attgtgctgt gcctcgtcac gtctgtcact gtggagtgga
3301 cagggctgaa ggtggccaag agactgcacc gcagcctgct aaaccggatc atcctagccc
3361 ccatgaggtt ttttgagacc acgccccttg ggagcatcct gaacagattt tcatctgact
3421 gtaacaccat cgaccagcac atcccatcca cgctggagtg cctgagccgc tccaccctgc
3481 tctgtgtctc agccctggcc gtcatctcct atgtcacacc tgtgttcctc gtggccctct
3541 tgcccctggc catcgtgtgc tacttcatcc agaagtactt ccgggtggcg tccagggacc
3601 tgcagcagct ggatgacacc acccagcttc cacttctctc acactttgcc gaaaccgtag
3661 aaggactcac caccatccgg gccttcaggt atgaggcccg gttccagcag aagcttctcg
3721 aatacacaga ctccaacaac attgcttccc tcttcctcac agctgccaac agatggctgg
3781 aagtccgaat ggagtacatc ggtgcatgtg tggtgctcat cgcagcggtg acctccatct
3841 ccaactccct gcacagggag ctctctgctg gcctggtggg cctgggcctt acctacgccc
3901 taatggtctc caactacctc aactggatgg tgaggaacct ggcagacatg gagctccagc
3961 tgggggctgt gaagcgcatc catgggctcc tgaaaaccga ggcagagagc tacgagggac
4021 tcctggcacc atcgctgatc ccaaagaact ggccagacca agggaagatc cagatccaga
4081 acctgagcgt gcgctacgac agctccctga agccggtgct gaagcacgtc aatgccctca
4141 tctcccctgg acagaagatc gggatctgcg gccgcaccgg cagtgggaag tcctccttct
4201 ctcttgcctt cttccgcatg gtggacacgt tcgaagggca catcatcatt gatggcattg
4261 acatcgccaa actgccgctg cacaccctgc gctcacgcct ctccatcatc ctgcaggacc
4321 ccgtcctctt cagcggcacc atccgattta acctggaccc tgagaggaag tgctcagata
4381 gcacactgtg ggaggccctg gaaatcgccc agctgaagct ggtggtgaag gcactgccag
4441 gaggcctcga tgccatcatc acagaaggcg gggagaattt cagccaggga cagaggcagc
4501 tgttctgcct ggcccgggcc ttcgtgagga agaccagcat cttcatcatg gacgaggcca
4561 cggcttccat tgacatggcc acggaaaaca tcctccaaaa ggtggtgatg acagccttcg
4621 cagaccgcac tgtggtcacc atcgcgcatc gagtgcacac catcctgagt gcagacctgg
4681 tgatcgtcct gaagcggggt gccatccttg agttcgataa gccagagaag ctgctcagcc
4741 ggaaggacag cgtcttcgcc tccttcgtcc gtgcagacaa gtgacctgcc agagcccaag
4801 tgccatccca cattcggacc ctgcccatac ccctgcctgg gttttctaac tgtaaatcac
4861 ttgtaaataa atagatttga ttatttccta aa
//