LOCUS       HUM5HSR                 1984 bp    mRNA    linear   HUM 21-MAR-1996
DEFINITION  Homo sapiens 5-HT6 serotonin receptor mRNA, complete cds.
ACCESSION   L41147
VERSION     L41147.1
KEYWORDS    5-HT6 serotonin receptor.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1984)
  AUTHORS   Kohen,R., Metcalf,M.A., Khan,N., Druck,T., Huebner,K.,
            Lachowicz,J.E., Meltzer,H.Y., Sibley,D.R., Roth,B.L. and
            Hamblin,M.W.
  TITLE     Cloning, characterization, and chromosomal localization of a human
            5-HT6 serotonin receptor
  JOURNAL   J. Neurochem. 66 (1), 47-56 (1996)
   PUBMED   8522988
COMMENT     Original source text: Homo sapiens adult Brain striatum cDNA to
            mRNA.
FEATURES             Location/Qualifiers
     source          1..1984
                     /db_xref="H-InvDB:HIT000193751"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /map="1p34-1pterm"
                     /tissue_type="Brain striatum"
                     /dev_stage="adult"
     mRNA            <1..>1984
     5'UTR           <1..467
     CDS             468..1790
                     /codon_start=1
                     /product="5-HT6 serotonin receptor"
                     /protein_id="AAA92622.1"
                     /translation="MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAAN
                     SLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLW
                     TAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFL
                     PLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQ
                     AVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGM
                     FFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRF
                     LPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGL
                     RLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN"
     3'UTR           1791..>1984
BASE COUNT          265 a          796 c          555 g          368 t
ORIGIN      
        1 cccgagagcg cccattcacc cccctcaccc acctccccgc gttcccactt ccccgcactc
       61 tgacccggcc ggacgcccct cccctatctt gccgcccgcc ccctccaggg ggctctgctc
      121 ccaccccagg gagcccatcc gacctctgct tgacttcccg ccgcttcctt caggggcctc
      181 ggctcatcgg gtgcccctcc ccaaacttcc aacccgtttg ctccaggagt tcctgcccca
      241 tccccgaggg cgcccaaata gccacactgt gtcctcctgt agtcgccgcc ccctgaccta
      301 gcgcgaccca gcgcccccgc ccatgtcccc ccactcacct cccccggggg gcgtggtgag
      361 tcgcggtctg ttctcacgga cggtccccgt ccagcctgcg cttcgccggg gccctcatct
      421 gctttcccgc caccctatca ctcccttgcc gtccaccctc ggtcctcatg gtcccagagc
      481 cgggcccaac cgccaatagc accccggcct ggggggcagg gccgccgtcg gccccggggg
      541 gcagcggctg ggtggcggcc gcgctgtgcg tggtcatcgc gctgacggcg gcggccaact
      601 cgctgctgat cgcgctcatc tgcactcagc ccgcgctgcg caacacgtcc aacttcttcc
      661 tggtgtcgct cttcacgtct gacctgatgg tggggctggt ggtgatgccg ccggccatgc
      721 tgaacgcgct gtacgggcgc tgggtgctgg cgcgcggcct ctgcctgctc tggaccgcct
      781 tcgacgtgat gtgctgcagc gcctccatcc tcaacctctg cctcatcagc ctggaccgct
      841 acctgctcat cctctcgccg ctgcgctaca agctgcgcat gacgcccctg cgtgccctgg
      901 ccctagtcct gggcgcctgg agcctcgccg ctctcgcctc cttcctgccc ctgctgctgg
      961 gctggcacga gctgggccac gcacggccac ccgtccctgg ccagtgccgc ctgctggcca
     1021 gcctgccttt tgtccttgtg gcgtcgggcc tcaccttctt cctgccctcg ggtgccatat
     1081 gcttcaccta ctgcaggatc ctgctagctg cccgcaagca ggccgtgcag gtggcctccc
     1141 tcaccaccgg catggccagt caggcctcgg agacgctgca ggtgcccagg accccacgcc
     1201 caggggtgga gtctgctgac agcaggcgtc tagccacgaa gcacagcagg aaggccctga
     1261 aggccagcct gacgctgggc atcctgctgg gcatgttctt tgtgacctgg ttgcccttct
     1321 ttgtggccaa catagtccag gccgtgtgcg actgcatctc cccaggcctc ttcgatgtcc
     1381 tcacatggct gggttactgt aacagcacca tgaaccccat catctaccca ctcttcatgc
     1441 gggacttcaa gcgggcgctg ggcaggttcc tgccatgtcc acgctgtccc cgggagcgcc
     1501 aggccagcct ggcctcgcca tcactgcgca cctctcacag cggcccccgg cccggcctta
     1561 gcctacagca ggtgctgccg ctgcccctgc cgccggactc agattcggac tcagacgcag
     1621 gctcaggcgg ctcctcgggc ctgcggctca cggcccagct gctgcttcct ggcgaggcca
     1681 cccaggaccc cccgctgccc accagggccg ctgccgccgt caatttcttc aacatcgacc
     1741 ccgcggagcc cgagctgcgg ccgcatccac ttggcatccc cacgaactga cccgggcttg
     1801 gggctggcca atggggagct ggattgagca gaacccagac cctgagtcct tgggccagct
     1861 cttggctaag accaggaggc tgcaagtctc ctagaagccc tctgagctcc agaggggtgc
     1921 gcagagctga ccccctgctg ccatctccag gccccttacc tgcagggatc atagctgact
     1981 caga
//