LOCUS       HUMAMY                  1549 bp    mRNA    linear   HUM 26-JAN-1994
DEFINITION  Human AD amyloid mRNA, complete cds.
ACCESSION   L08850
VERSION     L08850.1
KEYWORDS    AD amyloid; Alzheimer's disease; NACP; amyloid.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1549)
  AUTHORS   Ueda,K., Fukushima,H., Masliah,E., Xia,Y., Iwai,A., Yoshimoto,M.,
            Otero,D.A., Kondo,J., Ihara,Y. and Saitoh,T.
  TITLE     Molecular cloning of cDNA encoding an unrecognized component of
            amyloid in Alzheimer disease
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 90 (23), 11282-11286 (1993)
   PUBMED   8248242
COMMENT     Original source text: Homo sapiens cDNA to mRNA.
FEATURES             Location/Qualifiers
     source          1..1549
                     /db_xref="H-InvDB:HIT000191921"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /tissue_lib="ATCC 37432 of A. Lazzarini"
     terminator      35..473
     CDS             53..475
                     /standard_name="NACP"
                     /codon_start=1
                     /product="AD amyloid"
                     /protein_id="AAA16117.1"
                     /db_xref="GI:437365"
                     /translation="MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKT
                     KEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGK
                     NEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA"
     polyA_signal    1023..1028
     polyA_site      1023
     polyA_signal    1079..1084
     polyA_signal    1529..1534
     polyA_site      1549
BASE COUNT          471 a          248 c          342 g          488 t
ORIGIN      
        1 gctctcggag tggccattcg acgacagtgt ggtgtaaagg aattcattag ccatggatgt
       61 attcatgaaa ggactttcaa aggccaagga gggagttgtg gctgctgctg agaaaaccaa
      121 acagggtgtg gcagaagcag caggaaagac aaaagagggt gttctctatg taggctccaa
      181 aaccaaggag ggagtggtgc atggtgtggc aacagtggct gagaagacca aagagcaagt
      241 gacaaatgtt ggaggagcag tggtgacggg tgtgacagca gtagcccaga agacagtgga
      301 gggagcaggg agcattgcag cagccactgg ctttgtcaaa aaggaccagt tgggcaagaa
      361 tgaagaagga gccccacagg aaggaattct ggaagatatg cctgtggatc ctgacaatga
      421 ggcttatgaa atgccttctg aggaagggta tcaagactac gaacctgaag cctaagaaat
      481 atctttgctc ccagtttctt gagatctgct gacagatgtt ccatcctgta caagtgctca
      541 gttccaatgt gcccagtcat gacatttctc aaagttttta cagtgtatct cgaagtcttc
      601 catcagcagt gattgaagta tctgtacctg cccccactca gcatttcggt gcttcccttt
      661 cactgaagtg aatacatggt agcagggtct ttgtgtgctg tggattttgt ggcttcaatc
      721 tacgatgtta aaacaaatta aaaacaccta agtgactacc acttatttct aaatcctcac
      781 tatttttttg ttgctgttgt tcagaagttg ttagtgattt gctatcatat attataagat
      841 ttttaggtgt cttttaatga tactgtctaa gaataatgac gtattgtgaa atttgttaat
      901 atatataata cttaaaaata tgtgagcatg aaactatgca cctataaata ctaaatatga
      961 aattttacca ttttgcgatg tgttttattc acttgtgttt gtatataaat ggtgagaatt
     1021 aaaataaaac gttatctcat tgcaaaaata ttttattttt atcccatctc actttaataa
     1081 taaaaatcat gcttataagc aacatgaatt aagaactgac acaaaggaca aaaatataaa
     1141 gttattaata gccatttgaa gaaggaggaa ttttagaaga ggtagagaaa atggaacatt
     1201 aaccctacac tcggaattcc ctgaagcaac actgccagaa gtgtgttttg gtatgcactg
     1261 gttccttaag tggctgtgat taattattga aagtggggtg ttgaagaccc caactactat
     1321 tgtagagtgg tctatttctc ccttcaatcc tgtcaatgtt tgctttatgt attttgggga
     1381 actgttgttt gatgtgtatg tgtttataat tgttatacat ttttaattga gccttttatt
     1441 aacatatatt gttatttttg tctcgaaata attttttagt taaaatctat tttgtctgat
     1501 attggtgtga atgctgtacc tttctgacaa taaataatat tcgaccatg
//