LOCUS       HUMSEROTON              1554 bp    DNA     linear   HUM 26-JUL-1993
DEFINITION  Human serotonin receptor gene, complete cds.
ACCESSION   L05597
VERSION     L05597.1
KEYWORDS    5-hydroxytryptamine receptor; serotonin receptor.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1554)
  AUTHORS   Lovenberg,T.W., Erlander,M.G., Baron,B.M., Racke,M., Slone,A.L.,
            Siegel,B.W., Craft,C.M., Burns,J.E., Danielson,P.E. and
            Sutcliffe,J.G.
  TITLE     Molecular cloning and functional expression of 5-HT1E-like rat and
            human 5-hydroxytryptamine receptor genes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 90 (6), 2184-2188 (1993)
   PUBMED   8384716
COMMENT     Original source text: Homo sapiens male DNA.
FEATURES             Location/Qualifiers
     source          1..1554
                     /db_xref="H-InvDB:HIT000397384"
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /sex="male"
     CDS             225..1325
                     /function="inhibits adenylate cyclase"
                     /standard_name="5-HT1E receptor"
                     /note="putative"
                     /codon_start=1
                     /product="serotonin receptor"
                     /protein_id="AAA36605.1"
                     /translation="MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLV
                     IAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSV
                     DITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLF
                     WRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQAS
                     RIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEK
                     SWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAW
                     LGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC"
BASE COUNT          493 a          276 c          293 g          492 t
ORIGIN      
        1 actgttctca ttaaatttct taaataaaaa ggaaaactaa aaccttcaat ctgaacctca
       61 tttttttaat ctatagaata ttctgggtaa acataacata cactttttaa aaattattct
      121 gaaaggaaga gaaaagttct tgaagccttc tctgaactgt tttttctctt cccttgttac
      181 aggtatccat ttttcagcta tattaatctt ttaaaacaaa gaaaatggat ttcttaaatt
      241 catctgatca aaacttgacc tcagaggaac tgttaaacag aatgccatcc aaaattctgg
      301 tgtccctcac tctgtctggg ctggcactga tgacaacaac tatcaactcc cttgtgatcg
      361 ctgcaattat tgtgacccgg aagctgcacc atccagccaa ttatttaatt tgttcccttg
      421 cagtcacaga ttttcttgtg gctgtcctgg tgatgccctt cagcattgtg tatattgtga
      481 gagagagctg gattatgggg caagtggtct gtgacatttg gctgagtgtt gacattacct
      541 gctgcacgtg ctccatcttg catctctcag ctatagcttt ggatcggtat cgagcaatca
      601 cagatgctgt tgagtatgcc aggaaaagga ctccaaagca tgctggcatt atgattacaa
      661 tagtttggat tatatctgtt tttatctcta tgcctcctct attctggagg caccaaggaa
      721 ctagcagaga tgatgaatgc atcatcaagc acgaccacat tgtttccacc atttactcaa
      781 catttggagc tttctacatc ccactggcat tgattttgat cctttactac aaaatatata
      841 gagcagcaaa gacattatac cacaagagac aagcaagtag gattgcaaag gaggaggtga
      901 atggccaagt ccttttggag agtggtgaga aaagcactaa atcagtttcc acatcctatg
      961 tactagaaaa gtctttatct gacccatcaa cagactttga taaaattcat agcacagtga
     1021 gaagtctcag gtctgaattc aagcatgaga aatcttggag aaggcaaaag atctcaggta
     1081 caagagaacg gaaagcagcc actaccctgg gattaatctt gggtgcattt gtaatatgtt
     1141 ggcttccttt ttttgtaaaa gaattagttg ttaatgtctg tgacaaatgt aaaatttctg
     1201 aagaaatgtc caattttttg gcatggcttg ggtatctcaa ttcccttata aatccactga
     1261 tttacacaat ctttaatgaa gacttcaaga aagcattcca aaagcttgtg cgatgtcgat
     1321 gttagtttta aaaatgttta ttattgaagg atgggggttt ttgaggggag gaataactag
     1381 atgaatgcca aataataaaa cacttaagct tttagaggga aatacatgaa aactgctaaa
     1441 ttgataaggc tataatttat attttaatag caatgtgaat ataaaagtta ttgatcacca
     1501 ctattctagg gtattcaaaa ttagaaaata atttatgtag gttataacat attt
//