LOCUS AH002937 2535 bp DNA linear HUM 24-JAN-2017
DEFINITION Homo sapiens phosphoglycerate kinase (PGK1) gene, complete cds.
ACCESSION AH002937 J00288 L00159 L00160
VERSION AH002937.2
KEYWORDS phosphoglycerate kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 453 to 2535)
AUTHORS Michelson,A.M., Markham,A.F. and Orkin,S.H.
TITLE Isolation and DNA sequence of a full-length cDNA clone for human X
chromosome-encoded phosphoglycerate kinase
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 80 (2), 472-476 (1983)
PUBMED 6188151
REFERENCE 2 (bases 1448 to 1567)
AUTHORS Singer-Sam,J., Simmer,R.L., Keith,D.H., Shively,L., Teplitz,M.,
Itakura,K., Gartler,S.M. and Riggs,A.D.
TITLE Isolation of a cDNA clone for human X-linked 3-phosphoglycerate
kinase by use of a mixture of synthetic oligodeoxyribonucleotides
as a detection probe
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 80 (3), 802-806 (1983)
PUBMED 6572369
REFERENCE 3 (bases 1 to 2535)
AUTHORS Singer-Sam,J., Keith,D.H., Tani,K., Simmer,R.L., Shively,L.,
Lindsay,S., Yoshida,A. and Riggs,A.D.
TITLE Sequence of the promoter region of the gene for human X-linked
3-phosphoglycerate kinase]
JOURNAL Gene 32 (3), 409-417 (1984)
PUBMED 6099325
COMMENT On or before Jan 24, 2017 this sequence version replaced L00159.1,
L00160.1, AH002937.1.
FEATURES Location/Qualifiers
source 1..2535
/organism="Homo sapiens"
/mol_type="unassigned DNA"
/db_xref="taxon:9606"
/map="Xq13.3"
source 1..812
/organism="Homo sapiens"
/mol_type="unassigned DNA"
/db_xref="taxon:9606"
/map="Xq13.3"
/clone="lambda-PGK-TY1"
source 913..2535
/organism="Homo sapiens"
/mol_type="unassigned DNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq13.3"
/clone="pGK824; pHPGK-72"
/cell_line="LS174T"
/tissue_type="adenocarcinoma; liver"
/dev_stage="fetus"
gene 437..2101
/gene="PGK1"
mRNA join(437..596,913..>2101)
/gene="PGK1"
/product="phosphoglycerate kinase"
exon 437..596
/gene="PGK1"
/note="phosphoglycerate kinase; G00-120-282"
/number=1
misc_feature 438
/gene="PGK1"
/note="alternative mRNA start"
misc_feature 446
/gene="PGK1"
/note="alternative mRNA start"
CDS join(532..596,913..2101)
/gene="PGK1"
/EC_number="2.7.2.3"
/note="role in glycolysis"
/codon_start=1
/product="phosphoglycerate kinase"
/protein_id="AAA60078.1"
/translation="MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAV
PSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGP
EVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDV
YVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVA
DKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKN
GVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQI
VWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHV
STGGGASLELLEGKVLPGVDALSNI"
intron 597..>812
/gene="PGK1"
/number=A
gap 813..912
/estimated_length=unknown
BASE COUNT 549 a 598 c 683 g 605 t
ORIGIN
1 gaattccggg gttggggttg cgccttttcc aaggcagccc tgggtttgcg cagggacgcg
61 gctgctctgg gcgtggttcc gggaaacgca gcggcgccga ccctgggtct cgcacattct
121 tcacgtccgt tcgcagcgtc acccggatct tcgccgctac ccttgtgggc cccccggcga
181 cgcttcctcg tccgccccta agtcgggaag gttccttgcg gttcgcggcg tgccggacgt
241 gacaaacgga agccgcacgt ctcactagta ccctcgcaga cggacagcgc cagggagcaa
301 tggcagcgcg ccgaccgcga tgggctgtgg ccaatagcgg ctgctcagca gggcgcgccg
361 agagcagcgg ccgggaaggg gcggtgcggg aggcggggtg tggggcggta gtgtgggccc
421 tgttcctgcc cgcgcggtgt tccgcattct gcaagcctcc ggagcgcacg tcggcagtcg
481 gctccctcgt tgaccgaatc accgacctct ctccccagct gtatttccaa aatgtcgctt
541 tctaacaagc tgacgctgga caagctggac gttaaaggga agcgggtcgt tatgaggtaa
601 ttctgcacgt ttgcccgcgt gctctctgtg ctctgtcgca aacctctttg gccggagccg
661 acttgttctc tcgtctgctc taagttcttt tagcttttgg ctggccccag gggtcctagg
721 cttggagggc aggctgctca cgggtttggt ggtttctagc cgcattttcc ccagcccaga
781 aagcacccga agtcaccttc ggggatggat ccnnnnnnnn nnnnnnnnnn nnnnnnnnnn
841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
901 nnnnnnnnnn nnagtcgact tcaatgttcc tatgaagaac aaccagataa caaacaacca
961 gaggattaag gctgctgtcc caagcatcaa attctgcttg gacaatggag ccaagtcggt
1021 agtccttatg agccacctag gccggcctga tggtgtgccc atgcctgaca agtactcctt
1081 agagccagtt gctgtagaac tcaaatctct gctgggcaag gatgttctgt tcttgaagga
1141 ctgtgtaggc ccagaagtgg agaaagcctg tgccaaccca gctgctgggt ctgtcatcct
1201 gctggagaac ctccgctttc atgtggagga agaagggaag ggaaaagatg cttctgggaa
1261 caaggttaaa gccgagccag ccaaaataga agctttccga gcttcacttt ccaagctagg
1321 ggatgtctat gtcaatgatg cttttggcac tgctcacaga gcccacagct ccatggtagg
1381 agtcaatctg ccacagaagg ctggtgggtt tttgatgaag aaggagctga actactttgc
1441 aaaggccttg gagagcccag agcgaccctt cctggccatc ctgggcggag ctaaagttgc
1501 agacaagatc cagctcatca ataatatgct ggacaaagtc aatgagatga ttattggtgg
1561 tggaatggct tttaccttcc ttaaggtgct caacaacatg gagattggca cttctctgtt
1621 tgatgaagag ggagccaaga ttgtcaaaga cctaatgtcc aaagctgaga agaatggtgt
1681 gaagattacc ttgcctgttg actttgtcac tgctgacaag tttgatgaga atgccaagac
1741 tggccaagcc actgtggctt ctggcatacc tgctggctgg atgggcttgg actgtggtcc
1801 tgaaagcagc aagaagtatg ctgaggctgt cactcgggct aagcagattg tgtggaatgg
1861 tcctgtgggg gtatttgaat gggaagcttt tgcccgggga accaaagctc tcatggatga
1921 ggtggtgaaa gccacttcta ggggctgcat caccatcata ggtggtggag acactgccac
1981 ttgctgtgcc aaatggaaca cggaggataa agtcagccat gtgagcactg ggggtggtgc
2041 cagtttggag ctcctggaag gtaaagtcct tcctggggtg gatgctctca gcaatattta
2101 gtactttcct gccttttagt tcctgtgcac agcccctaag tcaacttagc attttctgca
2161 tctccacttg gcattagcta aaaccttcca tgtcaagatt cagctagtgg ccaagagatg
2221 cagtgccagg aacccttaaa cagttgcaca gcatctcagc tcatcttcac tgcaccctgg
2281 atttgcatac attcttcaag atcccatttg aattttttag tgactaaacc attgtgcatt
2341 ctagagtgca tatatttata ttttgcctgt taaaaagaaa gtgagcagtg ttagcttagt
2401 tctcttttga tgtaggttat tatgattagc tttgtcactg tttcactact cagcatggaa
2461 acaagatgaa attccatttg taggtagtga gacaaaattg atgatccatt aagtaaacaa
2521 taaaagtgtc cattg
//