LOCUS DQ191318 1822 bp mRNA linear INV 22-NOV-2005
DEFINITION Drosophila melanogaster p53 protein long form variant 1 (p53) mRNA,
complete cds, alternatively spliced.
ACCESSION DQ191318
VERSION DQ191318.1
KEYWORDS .
SOURCE Drosophila melanogaster (fruit fly)
ORGANISM Drosophila melanogaster
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE 1 (bases 1 to 1822)
AUTHORS Bourdon,J.C., Fernandes,K., Murray-Zmijewski,F., Liu,G., Diot,A.,
Xirodimas,D.P., Saville,M.K. and Lane,D.P.
TITLE p53 isoforms can regulate p53 transcriptional activity
JOURNAL Genes Dev. 19 (18), 2122-2137 (2005)
PUBMED 16131611
REFERENCE 2 (bases 1 to 1822)
AUTHORS Bourdon,J.C., Fernandes,K. and Lane,D.P.
TITLE Direct Submission
JOURNAL Submitted (31-AUG-2005) Surgery and Molecular Oncology, University
of Dundee, Ninewells Hospital, Dundee DD1 9SY, United Kingdom
FEATURES Location/Qualifiers
source 1..1822
/organism="Drosophila melanogaster"
/mol_type="mRNA"
/db_xref="taxon:7227"
gene 1..1822
/gene="p53"
CDS 15..1502
/gene="p53"
/note="dp53L; the long form of p53 contains the FxxFW
domain in the N-terminal end conserved through evolution
in all p53-related genes; alternatively spliced"
/codon_start=1
/product="p53 protein long form variant 1"
/protein_id="ABB80263.1"
/translation="MSLHKSASFSLTFNQNTSIVSRSNSRTIFEAFKEFLDFWDIGNE
VSAESAVRVSSNGAFNLPQSFGNESNEYAHLATPVDPAYGGNNTNNMMQFTNNLEILA
NNNSDGNNKINACNKFVCHKGTDSEDDSTEVDIKEDIPKTVEVSGSELTTEPMAFLQG
LNSGNLMQFSQQSVLREMMLQDIQIQANTLPKLENHNIGGYCFSMVLDEPPKSLWMYS
IPLNKLYIRMNKAFNVDVQFKSKMPIQPLNLRVFLCFSNDVSAPVVRCQNHLSVEPLT
ANNAKMRESLLRSENPNSVYCGNAQGKGISERFSVVVPLNMSRSVTRSGLTRQTLAFK
FVCQNSCIGRKETSLVFCLEKACGDIVGQHVIHVKICTCPKRDRIQDERQLNSKKRKS
VPEAAEEDEPSKVRRCIAIKTEDTESNDSRDCDDSAAEWNVSRTPDGDYRLAITCPNK
EWLLQSIEGMIKEAAAEVLRNPNQENLRRHANKLLSLKKRAYELP"
BASE COUNT 501 a 435 c 443 g 443 t
ORIGIN
1 ttgagtgcac agccatgagt cttcacaagt ccgcgtcgtt tagcttgact tttaaccaaa
61 acacttcgat tgtttcgcgt agcaatagtc gcacaatttt tgaagctttc aaggagttcc
121 tggatttttg ggatatcggc aacgaagttt ctgcagagtc agcagttcgg gtctccagca
181 acggagcttt caacttgccg cagagttttg gcaacgaatc caacgaatat gcccacctgg
241 ctacgcctgt ggatccagcc tacggaggca acaacacgaa caacatgatg cagttcacga
301 acaatctgga aattttggcc aacaataatt ccgatggcaa taacaaaatt aatgcatgca
361 acaaattcgt ctgccacaag ggcactgatt ccgaggatga ctccacggag gtcgatatca
421 aggaggatat tccgaaaacg gtggaggtat cgggatcgga attgaccacg gaacccatgg
481 ccttcttgca gggattaaac tccgggaatc tgatgcagtt cagccagcaa tccgtgctgc
541 gcgaaatgat gctgcaggac attcagatcc aggcgaacac gctgcccaag ctagagaatc
601 acaacatcgg tggttattgc ttcagcatgg ttctggatga gccgcccaag tctctttgga
661 tgtactcgat tccgctgaac aagctctaca tccggatgaa caaggccttc aacgtggacg
721 ttcagttcaa gtctaaaatg cccatccaac cacttaattt gcgtgtgttc ctttgcttct
781 ccaatgatgt gagtgctccc gtggtccgct gtcaaaatca ccttagcgtt gagcctttga
841 cggccaataa cgcaaaaatg cgcgagagct tgctgcgcag cgagaatccc aacagtgtat
901 attgtggaaa tgctcagggc aagggaattt ccgagcgttt ttccgttgta gtccccctga
961 acatgagccg gtctgtaacc cgcagtgggc tcacgcgcca gaccctggcc ttcaagttcg
1021 tctgccaaaa ctcgtgtatc gggcgaaaag aaacttcctt agtcttctgc ctggagaaag
1081 catgcggcga tatcgtggga cagcatgtta tacatgttaa aatatgtacg tgccccaagc
1141 gggatcgcat ccaagacgaa cgccagctca atagcaagaa gcgcaagtcc gtgccggaag
1201 ccgccgaaga agatgagccg tccaaggtgc gtcggtgcat tgctataaag acggaggaca
1261 cggagagcaa tgatagccga gactgcgacg actccgccgc agagtggaac gtgtcgcgga
1321 caccggatgg cgattaccgt ctggctatta cgtgccccaa taaggaatgg ctgctgcaga
1381 gcatcgaggg catgattaag gaggcggcgg ctgaagtcct gcgcaatccc aaccaagaga
1441 atctacgtcg ccatgccaac aaattgctga gccttaagaa acgtgcctac gagctgccat
1501 gacttctgat ctggtcgaca atctcccagg tatcagatac ctttgaaatg tgttgcatct
1561 gtggggtata ctacatagct attagtatct taagtttgta ttagtccttg ttcgtaaggc
1621 gtttaacggt gatattcccc ttttggcatg ttcgatggcc gaaaagaaaa catttttata
1681 tttttgatag tatactgttg ttaactgcag ttctatgtga ctacgtaact tttgtctacc
1741 acaacaaaca tactctgtac aaaaaagcca aaagtgaatt tattaaagag ttgtcatatt
1801 ttgcaaacaa aaaaaaaaaa aa
//