LOCUS D50134 2783 bp mRNA linear HUM 10-FEB-1999
DEFINITION Homo sapiens mRNA for inward rectifying K channel, complete cds.
ACCESSION D50134
VERSION D50134.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2783)
AUTHORS Kono,T.
TITLE Direct Submission
JOURNAL Submitted (11-APR-1995) to the DDBJ/EMBL/GenBank databases.
Contact:Takeshi Kono
Nippon Boehringer Ingelheim Co., Ltd., Molecular and Cellular
Biology Dept.; 3-10-1, Yato, Kawanishi, Hyogo 666-01, Japan
REFERENCE 2
AUTHORS Iizuka,M., Kubo,Y., Kono,T., Akiba,I. and Pan,X.
TITLE Isolation and functional expression of a novel cDNA clone that
encodes a inward rectifying potassium channel from porcine heart
JOURNAL Unpublished (1995)
REFERENCE 3
AUTHORS Iizuka,M., Kubo,Y., Tsunenari,I., Pan,C.X., Akiba,I. and Kono,T.
TITLE Functional characterization and localization of a cardiac-type
inwardly rectifying K+ channel
JOURNAL Recept. Channels 3, 299-315 (1995)
COMMENT
FEATURES Location/Qualifiers
source 1..2783
/clone_lib="lambda ZAPII"
/db_xref="H-InvDB:HIT000101542"
/db_xref="taxon:9606"
/mol_type="mRNA"
/organism="Homo sapiens"
/sex="male"
/tissue_type="heart"
5'UTR <1..270
CDS 271..1530
/codon_start=1
/product="inward rectifying K channel"
/protein_id="BAA08814.1"
/translation="MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLA
EGKKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWL
FFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEK
CPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLM
FRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLII
SHEINEKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFT
PVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEA
GLDAEAEQNEEDEPKGLGGSREARGSV"
3'UTR 1531..>2783
BASE COUNT 629 a 750 c 802 g 602 t
ORIGIN
1 caagagagag agagattgtt ccagctgctc tcgctagaga aagggagtga cccaaggggc
61 cgcgagtgaa gggacaggat ggcttaggta cctctgccca caggacccca caacagggag
121 aggttccagc tacagctcct ccgtggcgtc atggcagggg ctggggagtc ccctcaaaag
181 ccctgagccc ccctgcaccg ccgctaaggg acaccccaga agttagcatc agtgggactc
241 ggaagctccg atctcaacaa catcccagct atggctggcg attctaggaa tgccatgaac
301 caggacatgg agattggagt cactccctgg gaccccaaga agattccaaa acaggcccgc
361 gattatgtcc ccattgccac agaccgtacg cgcctgctgg ccgagggcaa gaagccacgc
421 cagcgctaca tggagaagag tggcaagtgc aacgtgcacc acggcaacgt ccaggagacc
481 taccggtacc tgagtgacct cttcaccacc ctggtggacc tcaagtggcg cttcaacttg
541 ctcgtcttca ccatggttta cactgtcacc tggctgttct tcggcttcat ttggtggctc
601 attgcttata tccggggtga cctggaccat gttggcgacc aagagtggat tccttgtgtt
661 gaaaacctca gtggcttcgt gtccgctttc ctgttctcca ttgagaccga aacaaccatt
721 gggtatggct tccgagtcat cacagagaag tgtccagagg ggattatact cctcttggtc
781 caggccatcc tgggctccat cgtcaatgcc ttcatggtgg ggtgcatgtt tgtcaagatc
841 agccagccca agaagagagc ggagaccctc atgttttcca acaacgcagt catctccatg
901 cgggacgaga agctgtgcct catgttccgg gtgggcgacc tccgcaactc ccacatcgtg
961 gaggcctcca tccgggccaa gctcatcaag tcccggcaga ccaaagaggg ggagttcatc
1021 cccctgaacc agacagacat caacgtgggc tttgacacgg gcgacgaccg cctcttcctt
1081 gtgtctcctc tgatcatctc ccatgagatc aacgagaaga gccctttctg ggagatgtct
1141 caggctcagc tgcatcagga agagtttgaa gttgtggtca ttctagaagg gatggtggaa
1201 gccacaggca tgacctgcca agcccggagc tcctacatgg atacagaggt gctctggggc
1261 caccgattca caccagtcct caccttggaa aagggcttct atgaggtgga ctacaacacc
1321 ttccatgata cctatgagac caacacaccc agctgctgtg ccaaggagct ggcagaaatg
1381 aagagggaag gccggctcct ccagtacctc cccagccccc cactgctggg gggctgtgct
1441 gaggcagggc tggatgcaga ggctgagcag aatgaagaag atgagcccaa ggggctgggt
1501 gggtccaggg aggccagggg ctcggtgtga ggggtgcaac ctccctaaga cctcctgtca
1561 ctggcttcag tgaacacaga cactgcagag cctgggagca ggggagggga atagttgagt
1621 gtgctgtttg ggggctcagg agccatcaag gctgtgggga ggaaccataa acccagccct
1681 cacagctccc agcacagggc ctccctgagc cagtggcatc ctgcctgggc cccccatggc
1741 agtgctgcct cttgtaggtg ctggctaagg gccaggccag gatgagtttc cccatggtga
1801 atgttaccgg atggcatctg ttctctccat gccctgggtc acttcctttt ttggggctca
1861 cagacccctc caggggctga cacctagaga gaaccatcac cttgtccctc attccttcca
1921 ccctgaggct tgctgtggac tcagagagga gacttacctg atgagagctc aaacctctag
1981 tctgggatga gctcacagag ccctcatgag ttaagatcca tccatatcac ataggcaatt
2041 ccttttaaat cagataccaa cgacccatta ctgagaggta cagagcgtac agcccgtggt
2101 gttctctgct gttatctgac aaatgtgtgt gtttcccctc tggtgtgttc tgtgtgtcca
2161 gtgtagccta ttggagaatc ggtctcatta gagtgactct tagaaggtgg cctgggacta
2221 gacagcccct ctgagcacat gtatagtggt atcaggaggt tcctggtcta ctcccaatca
2281 cactgtgccc tgcacctccc accagggggg gaaccccagg agctgggggt tcgcgagtgc
2341 tttttggccc aagattctca gagtgcttct aatcatcaca gtagagttgt gtgttgtgtt
2401 gtgttgtgtt gtgttgtgtt gtgttgtgtt gtgttgtgtt tttcacaatc tcagccagcc
2461 tgcggtgtga cctggggaga aagttgagtg tcaggggaca tgatgatcca ggttggccct
2521 gaaacaggaa tggggcaaag agaaaggaga gccaggagca tttaaaaatc agcatctggg
2581 ccaggcaaga tggctcacgc ctgtgatccc agcattttgg gagcccgagg cgggtggatc
2641 atgaggtcag gagatcgaga ccatcctggc taacacggtg aaaccccgtc tctactgaaa
2701 atacaaaaaa ttagccaggc atggtggcag gtgcctgtag tcccagctac tcgggaggct
2761 gaggcagaag aatggcatga acg
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