LOCUS D26579 3236 bp mRNA linear HUM 16-FEB-2008
DEFINITION Homo sapiens ms2 mRNA for transmembrane protein, complete cds.
ACCESSION D26579
VERSION D26579.1
KEYWORDS CD156; ADAM8; MS2.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3236)
AUTHORS Yamamoto,S.
TITLE Direct Submission
JOURNAL Submitted (20-JAN-1994) to the DDBJ/EMBL/GenBank databases.
Contact:Shunsuke Yamamoto
Oita Medical University, Department of Pathology; Hasama-machi,
Oita 879-55, Japan
REFERENCE 2
AUTHORS Yoshiyama,K., Setoguchi,M., Kaei,N., Matsuura,K., Higuchi,Y. and
Yamamoto,S.
TITLE Molecular cloning of human MS2, a myelomonocytic cell surface
protein which is a member of hemorrhagic snake venom family, and
its function
JOURNAL Unpublished (1994)
REFERENCE 3
AUTHORS Yoshiyama,K., Higuchi,Y., Kataoka,M., Matsuura,K. and Yamamoto,S.
TITLE CD156 (Human ADAM8): expression, primary amino acid sequence, and
gene location
JOURNAL Genomics 40 (1997) In press
COMMENT
FEATURES Location/Qualifiers
source 1..3236
/cell_line="THP-1"
/cell_type="macrophage, neutrophil leukocyte"
/clone_lib="THP-1"
/db_xref="H-InvDB:HIT000101161"
/db_xref="taxon:9606"
/dev_stage="adult"
/mol_type="mRNA"
/organism="Homo sapiens"
/tissue_type="blood"
5'UTR 1..9
CDS 10..2484
/codon_start=1
/function="metalloproteinase and platelet aggregation
inhibitor"
/gene="ms2"
/note="CD156; ADAM8; MS2"
/product="transmembrane protein"
/protein_id="BAA05626.1"
/translation="MRGLGLWLLGAMMLPAIAPSRPWALMEQYEVVLPRRLPGPRVRR
ALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEQPRGQ
DHCLYQGHVEGYPDSAASLSTCAGLRGFFQVGSDLHLIEPLDEGGEGGRHAVYQAEHL
LQTAGTCGVSDDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGS
EAAVRHRVLEVVNHVDKLYQKLNFRVVLVGLEIWNSQDRFHVSPDPSVTLENLLTWQA
RQRTRRHLHDNVQLITGVDFTGTTVGFARVSAMCSHSSGAVNQDHSKNPVGVACTMAH
EMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQ
SVCLANAPDLSHLVGGPVCGNLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAH
GTCCQECKVKPAGELCRPKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGGYCYNGAC
PTLAQQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGVLQCKGGQQPLGRAIC
IVDVCHALTTEDGTAYEPVPEGTRCGPEKVCWKGRCQDLHVYRSSNCSAQCHNHGVCN
HKQECHCHAGWAPPHCAKLLTEVHAASGSLPVLVVVVLVLLAVVLVTLAGIIVYRKAR
SRILSRNVAPKTTMGRSNPLFHQAASRVPAKGGAPAPSRGPQELVPTTHPGQPARHPA
SSVALKRPPPAPPVTVSSPPFPVPVYTRQAPKQVIKPTFAPPVPPVKPGAGAANPGPA
EGAVGPKVALKPPIQRKQGAGAPTAP"
sig_peptide 10..57
mat_peptide 58..2481
3'UTR 2482..3236
regulatory 3199..3204
/regulatory_class="polyA_signal_sequence"
BASE COUNT 580 a 1048 c 1010 g 598 t
ORIGIN
1 gacccggcca tgcgcggcct cgggctctgg ctgctgggcg cgatgatgct gcctgcgatt
61 gcccccagcc ggccctgggc cctcatggag cagtatgagg tcgtgttgcc gcggcgtctg
121 ccaggccccc gagtccgccg agctctgccc tcccacttgg gcctgcaccc agagagggtg
181 agctacgtcc ttggggccac agggcacaac ttcaccctcc acctgcggaa gaacagggac
241 ctgctgggtt ccggctacac agagacctat acggctgcca atggctccga ggtgacggag
301 cagcctcgcg ggcaggacca ctgcttatac cagggccacg tagaggggta cccggactca
361 gccgccagcc tcagcacctg tgccggcctc aggggtttct tccaggtggg gtcagacctg
421 cacctgatcg agcccctgga tgaaggtggc gagggcggac ggcacgccgt gtaccaggct
481 gagcacctgc tgcagacggc cgggacctgc ggggtcagcg acgacagcct gggcagcctc
541 ctgggacccc ggacggcagc cgtcttcagg cctcggcccg gggactctct gccatcccga
601 gagacccgct acgtggagct gtatgtggtc gtggacaatg cagagttcca gatgctgggg
661 agcgaagcag ccgtgcgtca tcgggtgctg gaggtggtga atcacgtgga caagctatat
721 cagaaactca acttccgtgt ggtcctggtg ggcctggaga tttggaatag tcaggacagg
781 ttccacgtca gccccgaccc cagtgtcaca ctggagaacc tcctgacctg gcaggcacgg
841 caacggacac ggcggcacct gcatgacaac gtacagctca tcacgggtgt cgacttcacc
901 gggactactg tggggtttgc cagggtgtcc gccatgtgct cccacagctc aggggctgtg
961 aaccaggacc acagcaagaa ccccgtgggc gtggcctgca ccatggccca tgagatgggc
1021 cacaacctgg gcatggacca tgatgagaac gtccagggct gccgctgcca ggaacgcttc
1081 gaggccggcc gctgcatcat ggcaggcagc attggctcca gtttccccag gatgttcagt
1141 gactgcagcc aggcctacct ggagagcttt ttggagcggc cgcagtcggt gtgcctcgcc
1201 aacgcccctg acctcagcca cctggtgggc ggccccgtgt gtgggaacct gtttgtggag
1261 cgtggggagc agtgcgactg cggccccccc gaggactgcc ggaaccgctg ctgcaactct
1321 accacctgcc agctggctga gggggcccag tgtgcgcacg gtacctgctg ccaggagtgc
1381 aaggtgaagc cggctggtga gctgtgccgt cccaagaagg acatgtgtga cctcgaggag
1441 ttctgtgacg gccggcaccc tgagtgcccg gaagacgcct tccaggagaa cggcacgccc
1501 tgctccgggg gctactgcta caacggggcc tgtcccacac tggcccagca gtgccaggcc
1561 ttctgggggc caggtgggca ggctgccgag gagtcctgct tctcctatga catcctacca
1621 ggctgcaagg ccagccggta cagggctgac atgtgtggcg ttctgcagtg caagggtggg
1681 cagcagcccc tggggcgtgc catctgcatc gtggatgtgt gccacgcgct caccacagag
1741 gatggcactg cgtatgaacc agtgcccgag ggcacccggt gtggaccaga gaaggtttgc
1801 tggaaaggac gttgccagga cttacacgtt tacagatcca gcaactgctc tgcccagtgc
1861 cacaaccatg gggtgtgcaa ccacaagcag gagtgccact gccacgcggg ctgggccccg
1921 ccccactgcg cgaagctgct gactgaggtg cacgcagcgt ccgggagcct ccccgtcctc
1981 gtggtggtgg ttctggtgct cctggcagtt gtgctggtca ccctggcagg catcatcgtc
2041 taccgcaaag cccggagccg catcctgagc aggaacgtgg ctcccaagac cacaatgggg
2101 cgctccaacc ccctgttcca ccaggctgcc agccgcgtgc cggccaaggg cggggctcca
2161 gccccatcca ggggccccca agagctggtc cccaccaccc acccgggcca gcccgcccga
2221 cacccggcct cctcggtggc tctgaagagg ccgccccctg ctcctccggt cactgtgtcc
2281 agcccaccct tcccagttcc tgtctacacc cggcaggcac caaagcaggt catcaagcca
2341 acgttcgcac ccccagtgcc cccagtcaaa cccggggctg gtgcggccaa ccctggtcca
2401 gctgagggtg ctgttggccc aaaggttgcc ctgaagcccc ccatccagag gaagcaagga
2461 gccggagctc ccacagcacc ctaggggggc acctgcgcct gtgtggaaat ttggagaagt
2521 tgcggcagag aagccatgcg ttccagcctt ccacggtcca gctagtgccg ctcagcccta
2581 gaccctgact ttgcaggctc agctgctgtt ctaacctcag taatgcatct acctgagagg
2641 ctcctgctgt ccacgccctc agccaattcc ttctccccgc cttggccacg tgtagcccca
2701 gctgtctgca ggcaccaggc tgggatgagc tgtgtgcttg cgggtgcgtg tgtgtgtacg
2761 tgtctccagg tggccgctgg tctcccgctg tgttcaggag gccacatata cagcccctcc
2821 cagccacacc tgcccctgct ctggggcctg ctgagccggc tgccctgggc acccggttcc
2881 aggcagcaca gacgtggggc atccccagaa agactccatc ccaggaccag gttcccctcc
2941 gtgctcttcg agagggtgtc agtgagcaga ctgcacccca agctcccgac tccaggtccc
3001 ctgatcttgg gcctgtttcc catgggattc aagagggaca gccccagctt tgtgtgtgtt
3061 taagcttagg aatgcccttt atggaaaggg ctatgtggga gagtcagcta tcttgtctgg
3121 ttttcttgag acctcagatg tgtgttcagc agggctgaaa gcttttattc tttaataatg
3181 agaaatgtat attttactaa taaattattg accgagttct gtagattctt gttaga
//