LOCUS       CP007027             4410911 bp    DNA     circular BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena, complete genome.
ACCESSION   CP007027
VERSION     CP007027.1
DBLINK      BioProject: PRJNA232612
            BioSample: SAMN03287041
KEYWORDS    .
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4410911
                     /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     gene            1..1524
                     /gene="dnaA"
                     /locus_tag="Y980_0001"
     CDS             1..1524
                     /gene="dnaA"
                     /locus_tag="Y980_0001"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00017"
                     /inference="protein motif:PROSITE:PS01008"
                     /note="Rv0001, (MT0001, MTV029.01, P49993) dnaA,
                     chromosomal replication initiator protein (see citations
                     below), equivalent to other Mycobacterial chromosomal
                     replication initiator proteins. Also highly similar to
                     others except in N-terminus e.g. Q9ZH75|DNAA_STRCH
                     chromosomal replication initiator protein from
                     Streptomyces chrysomallus (624 aa). Contains PS00017
                     ATP/GTP-binding site motif A (P-loop) and PS01008 DnaA
                     protein signature. Belongs to the DnaA family. Note that
                     the first base of this gene has been taken as base 1 of
                     the Mycobacterium tuberculosis H37Rv genomic sequence."
                     /codon_start=1
                     /transl_table=11
                     /product="Chromosomal replication initiator protein DnaA"
                     /protein_id="AJF01345.1"
                     /db_xref="GOA:P49993"
                     /db_xref="InterPro:IPR001957"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR010921"
                     /db_xref="InterPro:IPR013159"
                     /db_xref="InterPro:IPR013317"
                     /db_xref="InterPro:IPR018312"
                     /db_xref="InterPro:IPR020591"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/Swiss-Prot:P49993"
                     /translation="MTDDPGSGFTTVWNAVVSELNGDPKVDDGPSSDANLSAPLTPQQ
                     RAWLNLVQPLTIVEGFALLSVPSSFVQNEIERHLRAPITDALSRRLGHQIQLGVRIAP
                     PATDEADDTTVPPSENPATTSPDTTTDNDEIDDSAAARGDNQHSWPSYFTERPHNTDS
                     ATAGVTSLNRRYTFDTFVIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLL
                     HAAGNYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFI
                     EGKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLITDVQPPE
                     LETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALIRVTAFASLNKTPIDK
                     ALAEIVLRDLIADANTMQISAATIMAATAEYFDTTVEELRGPGKTRALAQSRQIAMYL
                     CRELTDLSLPKIGQAFGRDHTTVMYAQRKILSEMAERREVFDHVKELTTRIRQRSKR"
     gene            2052..3260
                     /gene="dnaN"
                     /locus_tag="Y980_0002"
     CDS             2052..3260
                     /gene="dnaN"
                     /locus_tag="Y980_0002"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0002, (MTV029.02, MTCY10H4.0) DnaN,DNA polymerase
                     III (beta chain) (see citations below),equivalent to other
                     Mycobacterial DNA polymerases III beta chain. Also highly
                     similar to others e.g. P27903|DP3B_STRCO DNA polymerase
                     III beta chain from Streptomyces coelicolor (376 aa).
                     Overlaps and extends CDS in neighbouring cosmid
                     MTCY10H4.01."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III (beta chain) DnaN (DNA
                     nucleotidyltransferase)"
                     /protein_id="AJF01346.1"
                     /db_xref="GOA:Q50790"
                     /db_xref="InterPro:IPR001001"
                     /db_xref="InterPro:IPR022634"
                     /db_xref="InterPro:IPR022635"
                     /db_xref="InterPro:IPR022637"
                     /db_xref="PDB:3P16"
                     /db_xref="PDB:3RB9"
                     /db_xref="UniProtKB/Swiss-Prot:Q50790"
                     /translation="MDAATTRVGLTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSG
                     VLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHV
                     EGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDT
                     LPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAG
                     IGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMD
                     VAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIA
                     FNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYV
                     YLLMPVRLPG"
     gene            3280..4437
                     /gene="recF"
                     /locus_tag="Y980_0003"
     CDS             3280..4437
                     /gene="recF"
                     /locus_tag="Y980_0003"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00017"
                     /inference="protein motif:PROSITE:PS00617"
                     /inference="protein motif:PROSITE:PS00618"
                     /note="Rv0003, (MTCY10H4.01) RecF, DNA replication and
                     repair protein (see citations below),equivalent to other
                     mycobacterial DNA replication and repair proteins. Also
                     highly similar to many others. Contains PS00017
                     ATP/GTP-binding site motif A (P-loop),PS00617 RecF protein
                     signature 1, and PS00618 RecF protein signature 2. Belongs
                     to the RecF family."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication and repair protein RecF
                     (single-strand DNA binding protein)"
                     /protein_id="AJF01347.1"
                     /db_xref="GOA:Q59586"
                     /db_xref="InterPro:IPR001238"
                     /db_xref="InterPro:IPR003395"
                     /db_xref="InterPro:IPR018078"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/Swiss-Prot:Q59586"
                     /translation="MYVRHLGLRDFRSWACVDLELHPGRTVFVGPNGYGKTNLIEALW
                     YSTTLGSHRVSADLPLIRVGTDRAVISTIVVNDGRECAVDLEIATGRVNKARLNRSSV
                     RSTRDVVGVLRAVLFAPEDLGLVRGDPADRRRYLDDLAIVRRPAIAAVRAEYERVLRQ
                     RTALLKSVPGARYRGDRGVFDTLEVWDSRLAEHGAELVAARIDLVNQLAPEVKKAYQL
                     LAPESRSASIGYRASMDVTGPSEQSDIDRQLLAARLLAALAARRDAELERGVCLVGPH
                     RDDLILRLGDQPAKGFASHGEAWSLAVALRLAAYQLLRVDGGEPVLLLDDVFAELDVM
                     RRRALATAAESAEQVLVTAAVLEDIPAGWDARRVHIDVRADDTGSMSVVLP"
     gene            4434..4997
                     /locus_tag="Y980_0004"
     CDS             4434..4997
                     /locus_tag="Y980_0004"
                     /note="Rv0004, (MTCY10H4.02) Conserved hypothetical
                     protein (see Salazar et al., 1996). Belongs to superfamily
                     DUF721; this family contains several actinomycete proteins
                     of unknown function."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01348.1"
                     /db_xref="InterPro:IPR007922"
                     /db_xref="InterPro:IPR023007"
                     /db_xref="UniProtKB/Swiss-Prot:P71573"
                     /translation="MTGSVDRPDQNRGERSMKSPGLDLVRRTLDEARAAARARGQDAG
                     RGRVASVASGRVAGRRRSWSGPGPDIRDPQPLGKAARELAKKRGWSVRVAEGMVLGQW
                     SAVVGHQIAEHARPTALNDGVLSVIAESTAWATQLRIMQAQLLAKIAAAVGNDVVRSL
                     KITGPAAPSWRKGPRHIAGRGPRDTYG"
     gene            5240..7267
                     /gene="gyrB"
                     /locus_tag="Y980_0005"
     CDS             5240..7267
                     /gene="gyrB"
                     /locus_tag="Y980_0005"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00177"
                     /note="Rv0005, (MTCY10H4.03) GyrB, DNA gyrase subunit B
                     (see citations below). Contains PS00177 DNA topoisomerase
                     II signature. Belongs to the type II topoisomerase family.
                     Start changed since first submission (-39 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase (subunit B) GyrB (DNA topoisomerase
                     (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA
                     topoisomerase)"
                     /protein_id="AJF01349.1"
                     /db_xref="GOA:P0C5C5"
                     /db_xref="InterPro:IPR001241"
                     /db_xref="InterPro:IPR002288"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR006171"
                     /db_xref="InterPro:IPR011557"
                     /db_xref="InterPro:IPR013506"
                     /db_xref="InterPro:IPR013759"
                     /db_xref="InterPro:IPR013760"
                     /db_xref="InterPro:IPR014721"
                     /db_xref="InterPro:IPR018522"
                     /db_xref="InterPro:IPR020568"
                     /db_xref="PDB:2ZJT"
                     /db_xref="PDB:3IG0"
                     /db_xref="PDB:3M4I"
                     /db_xref="UniProtKB/Swiss-Prot:P0C5C5"
                     /translation="MAAQKKKAQDEYGAASITILEGLEAVRKRPGMYIGSTGERGLHH
                     LIWEVVDNAVDEAMAGYATTVNVVLLEDGGVEVADDGRGIPVATHASGIPTVDVVMTQ
                     LHAGGKFDSDAYAISGGLHGVGVSVVNALSTRLEVEIKRDGYEWSQVYEKSEPLGLKQ
                     GAPTKKTGSTVRFWADPAVFETTEYDFETVARRLQEMAFLNKGLTINLTDERVTQDEV
                     VDEVVSDVAEAPKSASERAAESTAPHKVKSRTFHYPGGLVDFVKHINRTKNAIHSSIV
                     DFSGKGTGHEVEIAMQWNAGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKD
                     RKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQKVCNEQL
                     THWFEANPTDAKVVVNKAVSSAQARIAARKARELVRRKSATDIGGLPGKLADCRSTDP
                     RKSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITA
                     LGTGIHDEFDIGKLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIENGHVFLAQP
                     PLYKLKWQRSDPEFAYSDRERDGLLEAGLKAGKKINKEDGIQRYKGLGEMDAKELWET
                     TMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV"
     gene            7302..9818
                     /gene="gyrA"
                     /locus_tag="Y980_0006"
     CDS             7302..9818
                     /gene="gyrA"
                     /locus_tag="Y980_0006"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00018"
                     /note="Rv0006, (MTCY10H4.04) GyrA, DNA gyrase subunit A
                     (see citations below). Contains PS00018 EF-hand
                     calcium-binding domain."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase (subunit A) GyrA (DNA topoisomerase
                     (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA
                     topoisomerase)"
                     /protein_id="AJF01350.1"
                     /db_xref="GOA:Q07702"
                     /db_xref="InterPro:IPR002205"
                     /db_xref="InterPro:IPR005743"
                     /db_xref="InterPro:IPR006691"
                     /db_xref="InterPro:IPR013758"
                     /db_xref="InterPro:IPR013760"
                     /db_xref="InterPro:IPR024946"
                     /db_xref="PDB:3IFZ"
                     /db_xref="PDB:3ILW"
                     /db_xref="PDB:3UC1"
                     /db_xref="UniProtKB/Swiss-Prot:Q07702"
                     /translation="MTDTTLPPDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEV
                     RDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQP
                     WSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRV
                     QEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEETLAA
                     VMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEVEEDSRGRTSLVITELPY
                     QVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVIEIKRDAVAKVVINNLYKH
                     TQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILR
                     GLVKALDALDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQR
                     IIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGDDRRTRIIAADGDVSDE
                     DLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDL
                     ILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLV
                     LATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIR
                     FSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAKRTAIEEY
                     PVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQT
                     KGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN"
     gene            9914..10828
                     /locus_tag="Y980_0007"
     CDS             9914..10828
                     /locus_tag="Y980_0007"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0007, (MTCY10H4.05) Possible conserved membrane
                     protein. A core mycobacterial gene; conserved in
                     mycobacterial strains (See Marmiesse et al.,2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved membrane protein"
                     /protein_id="AJF01351.1"
                     /db_xref="GOA:P71575"
                     /db_xref="InterPro:IPR021949"
                     /db_xref="UniProtKB/Swiss-Prot:P71575"
                     /translation="MTAPNEPGALSKGDGPNADGLVDRGGAHRAATGPGRIPDAGDPP
                     PWQRAATRQSQAGHRQPPPVSHPEGRPTNPPAAADARLNRFISGASAPVTGPAAAVRT
                     PQPDPDASLGCGDGSPAEAYASELPDLSGPTPRAPQRNPAPARPAEGGAGSRGDSAAG
                     SSGGRSITAESRDARVQLSARRSRGPVRASMQIRRIDPWSTLKVSLLLSVALFFVWMI
                     TVAFLYLVLGGMGVWAKLNSNVGDLLNNASGSSAELVSSGTIFGGAFLIGLVNIVLMT
                     ALATIGAFVYNLITDLIGGIEVTLADRD"
     gene            10887..10960
                     /gene="ileT"
                     /locus_tag="Y980_nt001"
     tRNA            10887..10960
                     /gene="ileT"
                     /locus_tag="Y980_nt001"
                     /product="tRNA-Ile"
                     /note="codon recognized: AUC; ileT, tRNA-Ile, anticodon
                     gat, length = 74"
                     /anticodon=(pos:10921..10923,aa:Ile,seq:gat)
     gene            11112..11184
                     /gene="alaT"
                     /locus_tag="Y980_nt002"
     tRNA            11112..11184
                     /gene="alaT"
                     /locus_tag="Y980_nt002"
                     /product="tRNA-Ala"
                     /note="codon recognized: GCA; alaT, tRNA-Ala, anticodon
                     tgc, length = 73"
                     /anticodon=(pos:11145..11147,aa:Ala,seq:tgc)
     gene            complement(11874..12311)
                     /locus_tag="Y980_0008c"
     CDS             complement(11874..12311)
                     /locus_tag="Y980_0008c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0008c, (MTCY10H4.07c) Possible membrane protein."
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane protein"
                     /protein_id="AJF01352.1"
                     /db_xref="GOA:P71577"
                     /db_xref="InterPro:IPR024245"
                     /db_xref="UniProtKB/Swiss-Prot:P71577"
                     /translation="MSEQVETRLTPRERLTRGLAYSAVGPVDVTRGLLELGVGLGLQS
                     ARSTAAGLRRRYREGRLAREVAAAQETLAQELTAAQDVVANLPQALQDARTQRRSKHH
                     LWIFAGIAAAILAGGAVAFSIVRRSSRPEPSPRPPSVEVQPRS"
     gene            12468..13016
                     /gene="ppiA"
                     /locus_tag="Y980_0009"
                     /gene_synonym="cfp22"
     CDS             12468..13016
                     /gene="ppiA"
                     /locus_tag="Y980_0009"
                     /gene_synonym="cfp22"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0009, (MTCY10H4.08) Probable ppiA (alternate gene
                     name: cfp22), iron-regulated peptidyl-prolyl cis-trans
                     isomerase A. Belongs to the cyclophilin-type PPIase
                     family. Alternative start codon has been suggested."
                     /codon_start=1
                     /transl_table=11
                     /product="putative iron-regulated peptidyl-prolyl
                     cis-trans isomerase A PpiA (PPIase A) (rotamase A)"
                     /protein_id="AJF01353.1"
                     /db_xref="GOA:P65762"
                     /db_xref="InterPro:IPR002130"
                     /db_xref="InterPro:IPR020892"
                     /db_xref="InterPro:IPR024936"
                     /db_xref="PDB:1W74"
                     /db_xref="UniProtKB/Swiss-Prot:P65762"
                     /translation="MADCDSVTNSPLATATATLHTNRGDIKIALFGNHAPKTVANFVG
                     LAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQGFMIQGGDPTGTGRGGPGYKFADEFH
                     PELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNRRHTIFGEVIDAESQRVVEAIS
                     KTATDGNDRPTDPVVIESITIS"
     gene            complement(13133..13558)
                     /locus_tag="Y980_0010c"
     CDS             complement(13133..13558)
                     /locus_tag="Y980_0010c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0010c, (MTCY10H4.10c) Probable conserved membrane
                     protein. Belongs to superfamily DUF2581,conserved in the
                     Actinomycetales. A core mycobacterial gene; conserved in
                     mycobacterial strains (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved membrane protein"
                     /protein_id="AJF01354.1"
                     /db_xref="GOA:P71580"
                     /db_xref="InterPro:IPR019692"
                     /db_xref="UniProtKB/Swiss-Prot:P71580"
                     /translation="MQQTAWAPRTSGIAGCGAGGVVMAIASVTLVTDTPGRVLTGVAA
                     LGLILFASATWRARPRLAITPDGLAIRGWFRTQLLRHSNIKIIRIDEFRRYGRLVRLL
                     EIETVSGGLLILSRWDLGTDPVEVLDALTAAGYAGRGQR"
     gene            complement(13714..13995)
                     /locus_tag="Y980_0011c"
     CDS             complement(13714..13995)
                     /locus_tag="Y980_0011c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0011c, (MTCY10H4.11c) Probable conserved
                     transmembrane protein. Belongs to uncharacterized protein
                     family UPF0233. A core mycobacterial gene; conserved in
                     mycobacterial strains (See Marmiesse et al.,2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01355.1"
                     /db_xref="GOA:P67376"
                     /db_xref="InterPro:IPR009619"
                     /db_xref="InterPro:IPR027494"
                     /db_xref="UniProtKB/Swiss-Prot:P67376"
                     /translation="MPKSKVRKKNDFTVSAVSRTPMKVKVGPSSVWFVSLFIGLMLIG
                     LIWLMVFQLAAIGSQAPTALNWMAQLGPWNYAIAFAFMITGLLLTMRWH"
     gene            14089..14877
                     /locus_tag="Y980_0012"
     CDS             14089..14877
                     /locus_tag="Y980_0012"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0012, (MTCY10H4.12) Probable conserved membrane
                     protein. Belongs to superfamily DUF881. Contains probable
                     N-terminal signal sequence."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical membrane protein"
                     /protein_id="AJF01356.1"
                     /db_xref="InterPro:IPR010273"
                     /db_xref="UniProtKB/TrEMBL:L0T243"
                     /translation="MRLTHPTPCPENGETMIDRRRSAWRFSVPLVCLLAGLLLAATHG
                     VSGGTEIRRSDAPRLVDLVRRAQASVNRLATEREALTTRIDSVHGRSVDTALAAMQRR
                     SAKLAGVAAMNPVHGPGLVVTLQDAQRDANGRFPRDASPDDLVVHQQDIEAVLNALWN
                     AGAEAIQMQDQRIIAMSIARCVGNTLLLNGRTYSPPYTIAAIGDAAAMQAALAAAPLV
                     TLYKQYVVRFGLGYREEVHPDLQIVGYADPVRMHFAQPAGPLDY"
     gene            14914..15612
                     /gene="trpG"
                     /locus_tag="Y980_0013"
                     /gene_synonym="pabA"
     CDS             14914..15612
                     /gene="trpG"
                     /locus_tag="Y980_0013"
                     /gene_synonym="pabA"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00442"
                     /inference="protein motif:PROSITE:PS00606"
                     /note="Rv0013, (MTCY10H4.13) Possible trpG,anthranilate
                     synthase component II (glutamine amidotransferase).
                     Contains PS00606 Beta-ketoacyl synthases active site; and
                     PS00442 Glutamine amidotransferases class-I active site.
                     Similarity to other type-1 glutamine amidotransferase
                     domains. Note that previously known as pabA."
                     /codon_start=1
                     /transl_table=11
                     /product="putative anthranilate synthase component II TrpG
                     (glutamine amidotransferase)"
                     /protein_id="AJF01357.1"
                     /db_xref="GOA:Q7DAK6"
                     /db_xref="InterPro:IPR006221"
                     /db_xref="InterPro:IPR017926"
                     /db_xref="UniProtKB/Swiss-Prot:Q7DAK6"
                     /translation="MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVA
                     GQFDGVLLSPGPGTPERAGASVSIVHACAAAHTPLLGVCLGHQAIGVAFGATVDRAPE
                     LLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRVTARTSSGVIMAVQ
                     HTGLPIHGVQFHPESILTEGGHRILANWLTCCGWTQDDTLVRRLENEVLTAISPHFPT
                     STASAGEATGRTSA"
     gene            complement(15590..17470)
                     /gene="pknB"
                     /locus_tag="Y980_0014c"
     CDS             complement(15590..17470)
                     /gene="pknB"
                     /locus_tag="Y980_0014c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00107"
                     /inference="protein motif:PROSITE:PS00108"
                     /note="Rv0014c, (MTCY10H4.14c) PknB,transmembrane
                     serine/threonine-protein kinase (see citations below).
                     Contains PS00107 Protein kinases ATP-binding region
                     signature, and PS00108 Serine/Threonine protein kinases
                     active-site signature. Contains Hank's kinase subdomain.
                     Belongs to the Ser/Thr family of protein kinases.
                     Experimental studies show evidence of auto-phosphorylation
                     on serine/threonine residues. PknB has been shown to be a
                     substrate for PstP and its kinase activity is affected by
                     PstP-mediated dephosphorylation. PknB and PstP (Rv0018c)
                     may act as a functional pair in vivo to control
                     mycobacterial cell growth."
                     /codon_start=1
                     /transl_table=11
                     /product="Transmembrane serine/threonine-protein kinase B
                     PknB (protein kinase B) (STPK B)"
                     /protein_id="AJF01358.1"
                     /db_xref="GOA:P0A5S4"
                     /db_xref="InterPro:IPR000719"
                     /db_xref="InterPro:IPR002290"
                     /db_xref="InterPro:IPR005543"
                     /db_xref="InterPro:IPR008271"
                     /db_xref="InterPro:IPR011009"
                     /db_xref="InterPro:IPR017441"
                     /db_xref="PDB:1MRU"
                     /db_xref="PDB:1O6Y"
                     /db_xref="PDB:2FUM"
                     /db_xref="PDB:2KUD"
                     /db_xref="PDB:2KUE"
                     /db_xref="PDB:2KUF"
                     /db_xref="PDB:2KUI"
                     /db_xref="PDB:3F61"
                     /db_xref="PDB:3F69"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5S4"
                     /translation="MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRA
                     DLARDPSFYLRFRREAQNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTLRD
                     IVHTEGPMTPKRAIEVIADACQALNFSHQNGIIHRDVKPANIMISATNAVKVMDFGIA
                     RAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGEPPFTG
                     DSPVSVAYQHVREDPIPPSARHEGLSADLDAVVLKALAKNPENRYQTAAEMRADLVRV
                     HNGEPPEAPKVLTDAERTSLLSSAAGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVA
                     VVAVLAVLTVVVTIAINTFGGITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDS
                     TIPPDHVIGTDPAANTSVSAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFG
                     RFKQANSPSTPELVGKVIGTNPPANQTSAITNVVIIIVGSGPATKDIPDVAGQTVDVA
                     QKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTVPVDSVIELQVSKGNQFVMPDL
                     SGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQHNRVVYQNPPAGTGVNRDGIITLRF
                     GQ"
     gene            complement(17467..18762)
                     /gene="pknA"
                     /locus_tag="Y980_0015c"
     CDS             complement(17467..18762)
                     /gene="pknA"
                     /locus_tag="Y980_0015c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00108"
                     /note="Rv0015c, (MTCY10H4.15c) PknA,transmembrane
                     serine/threonine-protein kinase,magnesium/manganese
                     dependent (see citations below). Contains PS00108
                     Serine/Threonine protein kinases active-site signature.
                     Contains Hank's kinase subdomain. Belongs to the Ser/Thr
                     family of protein kinases. It has been shown that sodium
                     orthovanadate inhibits the activity of the enzyme in
                     vitro."
                     /codon_start=1
                     /transl_table=11
                     /product="Transmembrane serine/threonine-protein kinase A
                     PknA (protein kinase A) (STPK A)"
                     /protein_id="AJF01359.1"
                     /db_xref="GOA:P65726"
                     /db_xref="InterPro:IPR000719"
                     /db_xref="InterPro:IPR008271"
                     /db_xref="InterPro:IPR011009"
                     /db_xref="UniProtKB/Swiss-Prot:P65726"
                     /translation="MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVL
                     KSEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESQMNGEGRTAYLVMELVNGEP
                     LNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDF
                     GIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFA
                     GDGALTVAMKHIKEPPPPLPPDLPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRA
                     GRRPPRPSQTPPPGRAAPAAIPSGTTARVAANSAGRTAASRRSRPATGGHRPPRRTFS
                     SGQRALLWAAGVLGALAIIIAVLLVIKAPGDNSPQQAPTPTVTTTGNPPASNTGGTDA
                     SPRLNWTERGETRHSGLQSWVVPPTPHSRASLARYEIAQ"
     gene            complement(18759..20234)
                     /gene="pbpA"
                     /locus_tag="Y980_0016c"
     CDS             complement(18759..20234)
                     /gene="pbpA"
                     /locus_tag="Y980_0016c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0016c, (MTCY10H4.16c) Probable
                     pbpA,penicillin-binding protein, similar to many."
                     /codon_start=1
                     /transl_table=11
                     /product="putative penicillin-binding protein PbpA"
                     /protein_id="AJF01360.1"
                     /db_xref="GOA:P71586"
                     /db_xref="InterPro:IPR001460"
                     /db_xref="InterPro:IPR012338"
                     /db_xref="PDB:3LO7"
                     /db_xref="PDB:3UN7"
                     /db_xref="PDB:3UPN"
                     /db_xref="PDB:3UPO"
                     /db_xref="PDB:3UPP"
                     /db_xref="UniProtKB/Swiss-Prot:P71586"
                     /translation="MNASLRRISVTVMALIVLLLLNATMTQVFTADGLRADPRNQRVL
                     LDEYSRQRGQITAGGQLLAYSVATDGRFRFLRVYPNPEVYAPVTGFYSLRYSSTALER
                     AEDPILNGSDRRLFGRRLADFFTGRDPRGGNVDTTINPRIQQAGWDAMQQGCYGPCKG
                     AVVALEPSTGKILALVSSPSYDPNLLASHNPEVQAQAWQRLGDNPASPLTNRAISETY
                     PPGSTFKVITTAAALAAGATETEQLTAAPTIPLPGSTAQLENYGGAPCGDEPTVSLRE
                     AFVKSCNTAFVQLGIRTGADALRSMARAFGLDSPPRPTPLQVAESTVGPIPDSAALGM
                     TSIGQKDVALTPLANAEIAATIANGGITMRPYLVGSLKGPDLANISTTVGYQQRRAVS
                     PQVAAKLTELMVGAEKVAQQKGAIPGVQIASKTGTAEHGTDPRHTPPHAWYIAFAPAQ
                     APKVAVAVLVENGADRLSATGGALAAPIGRAVIEAALQGEP"
     gene            complement(20231..21640)
                     /gene="rodA"
                     /locus_tag="Y980_0017c"
                     /gene_synonym="ftsW"
     CDS             complement(20231..21640)
                     /gene="rodA"
                     /locus_tag="Y980_0017c"
                     /gene_synonym="ftsW"
                     /note="Rv0017c, (MTCY10H4.17c) Probable rodA (alternate
                     gene name: ftsW), cell division protein,integral membrane
                     protein. Belongs to the FTSW/RODA/SPOVE family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cell division protein RodA"
                     /protein_id="AJF01361.1"
                     /db_xref="GOA:P63760"
                     /db_xref="InterPro:IPR001182"
                     /db_xref="InterPro:IPR018365"
                     /db_xref="UniProtKB/Swiss-Prot:P63760"
                     /translation="MTTRLQAPVAVTPPLPTRRNAELLLLCFAAVITFAALLVVQANQ
                     DQGVPWDLTSYGLAFLTLFGSAHLAIRRFAPYTDPLLLPVVALLNGLGLVMIHRLDLV
                     DNEIGEHRHPSANQQMLWTLVGVAAFALVVTFLKDHRQLARYGYICGLAGLVFLAVPA
                     LLPAALSEQNGAKIWIRLPGFSIQPAEFSKILLLIFFSAVLVAKRGLFTSAGKHLLGM
                     TLPRPRDLAPLLAAWVISVGVMVFEKDLGASLLLYTSFLVVVYLATQRFSWVVIGLTL
                     FAAGTLVAYFIFEHVRLRVQTWLDPFADPDGTGYQIVQSLFSFATGGIFGTGLGNGQP
                     DTVPAASTDFIIAAFGEELGLVGLTAILMLYTIVIIRGLRTAIATRDSFGKLLAAGLS
                     STLAIQLFIVVGGVTRLIPLTGLTTPWMSYGGSSLLANYILLAILARISHGARRPLRT
                     RPRNKSPITAAGTEVIERV"
     gene            complement(21637..23181)
                     /gene="pstP"
                     /locus_tag="Y980_0018c"
     CDS             complement(21637..23181)
                     /gene="pstP"
                     /locus_tag="Y980_0018c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0018c, (MTCY10H4.18c)
                     PstP,phosphoserine/threonine phosphatase. Experimental
                     studies have shown that PstP specifically dephosporylates
                     model phospho-Ser/Thr substrates and it is likely that
                     PknB (Rv0014c) and PstP may act as a functional pair in
                     vivo to control mycobacterial cell growth (See Boitel et
                     al.,2003)."
                     /codon_start=1
                     /transl_table=11
                     /product="Phosphoserine/threonine phosphatase PstP"
                     /protein_id="AJF01362.1"
                     /db_xref="GOA:P71588"
                     /db_xref="InterPro:IPR001932"
                     /db_xref="InterPro:IPR015655"
                     /db_xref="PDB:1TXO"
                     /db_xref="PDB:2CM1"
                     /db_xref="UniProtKB/Swiss-Prot:P71588"
                     /translation="MARVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHA
                     AGEVASQLVIAALAHLDDDEPGGDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTTLT
                     AILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRS
                     LIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRL
                     IELALRGGGPDNVTVVVADVVDYDYGQTQPILAGAVSGDDDQLTLPNTAAGRASAISQ
                     RKEIVKRVPPQADTFSRPRWSGRRLAFVVALVTVLMTAGLLIGRAIIRSNYYVADYAG
                     SVSIMRGIQGSLLGMSLHQPYLMGCLSPRNELSQISYGQSGGPLDCHLMKLEDLRPPE
                     RAQVRAGLPAGTLDDAIGQLRELAANSLLPPCPAPRATSPPGRPAPPTTSETTEPNVT
                     SSPASPSPTTSAPAPTGTTPAIPTSASPAAPASPPTPWPVTSSPTMAALPPPPPQPGI
                     DCRAAA"
     repeat_region   complement(23173..23273)
                     /note="101 bp Mycobacterial Interspersed Repetitive
                     Unit,Class I. See Supply et al. (1997) Molecular
                     Microbiology 26, 991-1003"
     gene            complement(23270..23737)
                     /gene="fhaB"
                     /locus_tag="Y980_0019c"
     CDS             complement(23270..23737)
                     /gene="fhaB"
                     /locus_tag="Y980_0019c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0019c, (MTCY10H4.19c) FhaB,conserved protein with
                     forkhead-associated domain (IPR000253), probably involved
                     in signal transduction."
                     /codon_start=1
                     /transl_table=11
                     /product="Conserved protein with FHA domain, FhaB"
                     /protein_id="AJF01363.1"
                     /db_xref="GOA:P71589"
                     /db_xref="InterPro:IPR000253"
                     /db_xref="InterPro:IPR008984"
                     /db_xref="UniProtKB/Swiss-Prot:P71589"
                     /translation="MQGLVLQLTRAGFLMLLWVFIWSVLRILKTDIYAPTGAVMMRRG
                     LALRGTLLGARQRRHAARYLVVTEGALTGARITLSEQPVLIGRADDSTLVLTDDYAST
                     RHARLSMRGSEWYVEDLGSTNGTYLDRAKVTTAVRVPIGTPVRIGKTAIELRP"
     gene            complement(23861..25444)
                     /gene="fhaA"
                     /locus_tag="Y980_0020c"
                     /gene_synonym="TB39.8"
     CDS             complement(23861..25444)
                     /gene="fhaA"
                     /locus_tag="Y980_0020c"
                     /gene_synonym="TB39.8"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0020c, (MTCY10H4.20c) FhaA, TB39.8,conserved
                     protein with forkhead-associated domain (IPR000253) at
                     C-terminus, may be involved in signal transduction.
                     Alternative start codon in position 24979 has been
                     suggested (see citation below). A core mycobacterial gene;
                     conserved in mycobacterial strains (See Marmiesse et al.,
                     2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="Conserved protein with FHA domain, FhaA"
                     /protein_id="AJF01364.1"
                     /db_xref="GOA:P71590"
                     /db_xref="InterPro:IPR000253"
                     /db_xref="InterPro:IPR008984"
                     /db_xref="InterPro:IPR022128"
                     /db_xref="PDB:2LC0"
                     /db_xref="PDB:2LC1"
                     /db_xref="PDB:3OUN"
                     /db_xref="PDB:3PO8"
                     /db_xref="PDB:3POA"
                     /db_xref="UniProtKB/Swiss-Prot:P71590"
                     /translation="MGSQKRLVQRVERKLEQTVGDAFARIFGGSIVPQEVEALLRREA
                     ADGIQSLQGNRLLAPNEYIITLGVHDFEKLGADPELKSTGFARDLADYIQEQGWQTYG
                     DVVVRFEQSSNLHTGQFRARGTVNPDVETHPPVIDCARPQSNHAFGAEPGVAPMSDNS
                     SYRGGQGQGRPDEYYDDRYARPQEDPRGGPDPQGGSDPRGGYPPETGGYPPQPGYPRP
                     RHPDQGDYPEQIGYPDQGGYPEQRGYPEQRGYPDQRGYQDQGRGYPDQGQGGYPPPYE
                     QRPPVSPGPAAGYGAPGYDQGYRQSGGYGPSPGGGQPGYGGYGEYGRGPARHEEGSYV
                     PSGPPGPPEQRPAYPDQGGYDQGYQQGATTYGRQDYGGGADYTRYTESPRVPGYAPQG
                     GGYAEPAGRDYDYGQSGAPDYGQPAPGGYSGYGQGGYGSAGTSVTLQLDDGSGRTYQL
                     REGSNIIGRGQDAQFRLPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQEWQ
                     LADGDVIRLGHSEIIVRMH"
     gene            25644..25726
                     /gene="leuT"
                     /locus_tag="Y980_nt003"
     tRNA            25644..25726
                     /gene="leuT"
                     /locus_tag="Y980_nt003"
                     /product="tRNA-Leu"
                     /note="codon recognized: CUG; leuT, tRNA-Leu, anticodon
                     cag, length = 83"
                     /anticodon=(pos:25677..25679,aa:Leu,seq:cag)
     gene            complement(25913..26881)
                     /locus_tag="Y980_0021c"
     CDS             complement(25913..26881)
                     /locus_tag="Y980_0021c"
                     /note="Rv0021c, (MTCY10H4.21c) Conserved hypothetical
                     protein, similar to various proteins."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01365.1"
                     /db_xref="GOA:L7N625"
                     /db_xref="HSSP:P12268"
                     /db_xref="InterPro:IPR004136"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="UniProtKB/TrEMBL:L7N625"
                     /translation="MVLSTAFSQMFGIDYPIVSAPMDLIAGGELAAAVSGAGGLGLIG
                     GGYGDRDWLARQFDLAAGAPVGCGFITWSLARQPQLLDLALQYEPVAVMLSFGDPAVF
                     ADAIKSAGTRLVCQIQNRTQAERALQVGADVLVAQGTEAGGHGHGPRSTLTLVPEIVD
                     LVTARGTDIPVIAAGGIADGRGLAAALMLGAAGVLVGTRFYATVEALSTPQARDPLLA
                     ATGDDMCRTTIYDQLRRYPWPQGHTMSVLSNALTDQFEDTELDILHREEAMARYWRAV
                     AARDYSIANVTAGQAAGLVNAVLPAADVITGMAQQAARTLTAMRAV"
     gene            complement(27023..27442)
                     /gene="whiB5"
                     /locus_tag="Y980_0022c"
                     /gene_synonym="whmG"
     CDS             complement(27023..27442)
                     /gene="whiB5"
                     /locus_tag="Y980_0022c"
                     /gene_synonym="whmG"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0022c, (MTCY10H4.22c) Probable whiB5 (alternate
                     gene name: whmG), WhiB-like regulatory protein (see
                     citations below), similar to WhiB paralogue of
                     Streptomyces coelicolor, wblE gene product (85 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein
                     WhiB-like WhiB5"
                     /protein_id="AJF01366.1"
                     /db_xref="GOA:P71592"
                     /db_xref="InterPro:IPR003482"
                     /db_xref="UniProtKB/Swiss-Prot:P71592"
                     /translation="MAHPCATDPELWFGYPDDDGSDGAAKARAYERSATQARIQCLRR
                     CPLLQQRRCAQHAVEHRVEYGVWAGIKLPGGQYRKREQLAAAHDVLRRIAGGEINSRQ
                     LPDNAALLARNEGLEVTPVPGVVVHLPIAQVGPQPAA"
     gene            27595..28365
                     /locus_tag="Y980_0023"
     CDS             27595..28365
                     /locus_tag="Y980_0023"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0023, (MTCY10H4.23) Possible transcriptional
                     regulator. Contains probable helix-turn helix motif from
                     aa 19 to 40 (Score 1615, +4.69 SD)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein"
                     /protein_id="AJF01367.1"
                     /db_xref="GOA:P67704"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="InterPro:IPR010982"
                     /db_xref="UniProtKB/Swiss-Prot:P67704"
                     /translation="MSRESAGAAIRALRESRDWSLADLAAATGVSTMGLSYLERGARK
                     PHKSTVQKVENGLGLPPGTYSRLLVAADPDAELARLIAAQPSNPTAVRRAGAVVVDRH
                     SDTDVLEGYAEAQLDAIKSVIDRLPATTSNEYETYILSVIAQCVKAEMLAASSWRVAV
                     NAGADSTGRLMEHLRALEATRGALLERMPTSLSARFDRACAQSSLPEAVVAALIGVGA
                     DEMWDIRNRGVIPAGALPRVRAFVDAIEASHDADEGQQ"
     gene            28362..29207
                     /locus_tag="Y980_0024"
     CDS             28362..29207
                     /locus_tag="Y980_0024"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0024, (MTCY10H4.24) Putative secreted protein,
                     p60 homologue, similar to many. Similar to Mycobacterium
                     tuberculosis proteins Rv1477, Rv1478,Rv1566c, Rv2190c.
                     Could belong to the E. coli NLPC / listeria P60 family."
                     /codon_start=1
                     /transl_table=11
                     /product="Putative secreted protein P60-related protein"
                     /protein_id="AJF01368.1"
                     /db_xref="InterPro:IPR000064"
                     /db_xref="UniProtKB/TrEMBL:L7N550"
                     /translation="MNYSEVELLSRAHQLFAGDSRRPGLDAGTTPYGDLLSRAADLNV
                     GAGQRRYQLAVDHSRAALLSAARTDAAAGAVITGAQRDRAWARRSTGTVLDEARSDTT
                     VTAVMPIAQREAIRRRVARLRAQRAHVLTARRRARRHLAALRALRYRVAHGPGVALAK
                     LRLPSPSGRAGIAVHAALSRLGRPYVWGATGPNQFDCSGLVQWAYAQAGVHLDRTTYQ
                     QINEGIPVPRSQVRPGDLVFPHPGHVQLAIGNNLVVEAPHAGASVRVSSLGNNVQIRR
                     PLSGR"
     gene            29245..29607
                     /locus_tag="Y980_0025"
     CDS             29245..29607
                     /locus_tag="Y980_0025"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0025, (MTCY10H4.25) Conserved hypothetical
                     protein, showing some similarity to other proteins from
                     Mycobacterium tuberculosis e.g. Rv0739 (268 aa)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01369.1"
                     /db_xref="InterPro:IPR019710"
                     /db_xref="UniProtKB/Swiss-Prot:P71595"
                     /translation="MSEQAGSSVAVIQERQALLARQHDAVAEADRELADVLASAHAAM
                     RESVRRLDAIAAELDRAVPDQDQLAVDTPMGAREFQTFLVAKQREIVAVVAAAHELDR
                     AKSAVLKRLRAQYTEPAR"
     gene            29722..31068
                     /locus_tag="Y980_0026"
     CDS             29722..31068
                     /locus_tag="Y980_0026"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0026, (MTCY10H4.26) Conserved hypothetical
                     protein, showing some similarity to other proteins from
                     Mycobacterium tuberculosis: Rv0025"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01370.1"
                     /db_xref="InterPro:IPR019710"
                     /db_xref="UniProtKB/Swiss-Prot:P71596"
                     /translation="MAFDAAMSTHEDLLATIRYVRDRTGDPNAWQTGLTPTEVTAVVT
                     STTRSEQLDAILRKIRQRHSNLYYPAPPDREQGDAARAIADAEAALAHQNSATAQLDL
                     QVVSAILNAHLKTVEGGESLHELQQEIEAAVRIRSDLDTPAGARDFQRFLIGKLKDIR
                     EVVATASLDAASKSALMAAWTSLYDASKGDRGDADDRGPASVGSGGAPARGAGQQPEL
                     PTRAEPDCLLDSLLLEDPGLLADDLQVPGGTSAAIPSASSTPSLPNLGGATMPGGGAT
                     PALVPGVSAPGGLPLSGLLRGVGDEPELTDFDERGQEVRDPADYEHSNEPDERRADDR
                     EGADEDAGLGKSESPPQAPTTVTLPNGETVTAASPQLAAAIKAAASGTPIADAFQQQG
                     IAIPLPGTAVANPVDPARISAGDVGVFTATPLPLALAKLFWTARFNTSQPCEGQTF"
     gene            31189..31506
                     /locus_tag="Y980_0027"
     CDS             31189..31506
                     /locus_tag="Y980_0027"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0027, (MTCY10H4.27) Conserved hypothetical
                     unknown protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01371.1"
                     /db_xref="InterPro:IPR022536"
                     /db_xref="UniProtKB/Swiss-Prot:P64667"
                     /translation="MTDRIHVQPAHLRQAAAHHQQTADYLRTVPSSHDAIRESLDSLG
                     PIFSELRDTGRELLELRKQCYQQQADNHADIAQNLRTSAAMWEQHERAASRSLGNIID
                     GSR"
     gene            31514..31819
                     /locus_tag="Y980_0028"
     CDS             31514..31819
                     /locus_tag="Y980_0028"
                     /note="Rv0028, (MTCY10H4.28) Conserved hypothetical
                     unknown protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01372.1"
                     /db_xref="InterPro:IPR024426"
                     /db_xref="UniProtKB/Swiss-Prot:P64669"
                     /translation="MTDANPAFDTVHPSGHILVRSCRGGYMHSVSLSEAAMETDAETL
                     AEAILLTADVSCLKALLEVRNEIVAAGHTPSAQVPTTDDLNVAIEKLLAHQLRRRNR"
     gene            32057..33154
                     /locus_tag="Y980_0029"
     CDS             32057..33154
                     /locus_tag="Y980_0029"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0029, (MTCY10H4.29) Conserved hypothetical
                     protein, showing some similarity to other proteins from
                     Mycobacterium tuberculosis e.g. C-terminal region of
                     Rv2082; Rv3899c."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01373.1"
                     /db_xref="UniProtKB/TrEMBL:L0T5H2"
                     /translation="MAIFGRWSARQRLRRATRESLTIPTFSSSLDCTTRVIGGLWPAE
                     LSSNTAETATLAEHLKADLHRIVGSANDELMVIWRAGMADSTRRAEEDRVIDRARASA
                     MRRVESAMRELRQITGRVPVEIPRMRGAGGSDLDTTRLMPAVTVVQPADQACTDWPVA
                     AAEDDEARLQRLLAFVARQEPRLNWAVGVHADGTTVLVTDVAHGWIPPGIALPEGVRL
                     LAPARRAGRAPELVGITTCCKTYTPGDSLRRAVDSTAPTSSVQPRALPAIAGLSVELG
                     IATQRHDGLPKIVHAMATAAGNGAAAEEVDLLRVHVDTALHHVLAQYPRVDPALLLNC
                     MLLAATERSVTGDPIAANYHFAWFRELDSRR"
     gene            33224..33553
                     /locus_tag="Y980_0030"
     CDS             33224..33553
                     /locus_tag="Y980_0030"
                     /note="Rv0030, (MTCY10H4.30) Conserved hypothetical
                     unknown protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01374.1"
                     /db_xref="InterPro:IPR024296"
                     /db_xref="UniProtKB/Swiss-Prot:P64671"
                     /translation="MVSGSDSRSEPSQLSDRDLVESVLRDLSEAADKWEALVTQAETV
                     TYSVDLGDVRAVANSDGRLLELTLHPGVMTGYAHGELADRVNLAITALRDEVEAENRA
                     RYGGRLQ"
     misc_feature    33582..33794
                     /note="transposase remnant"
     gene            34295..36610
                     /gene="bioF2"
                     /locus_tag="Y980_0032"
     CDS             34295..36610
                     /gene="bioF2"
                     /locus_tag="Y980_0032"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00599"
                     /note="Rv0032, (MTCY10H4.32) Probable
                     bioF2,8-amino-7-oxononanoate synthase, with its C-terminal
                     similar to others. Contains PS00599 Aminotransferases
                     class-II pyridoxal-phosphate attachment site. Belongs to
                     class-II of pyridoxal-phosphate-dependent
                     aminotransferases."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 8-amino-7-oxononanoate synthase BioF2
                     (AONS) (8-amino-7-ketopelargonate synthase)
                     (7-keto-8-amino-pelargonic acid synthetase) (7-KAP
                     synthetase) (L-alanine--pimelyl CoA ligase)"
                     /protein_id="AJF01375.1"
                     /db_xref="GOA:P71602"
                     /db_xref="InterPro:IPR001917"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="InterPro:IPR016181"
                     /db_xref="UniProtKB/Swiss-Prot:P71602"
                     /translation="MPTGLGYDFLRPVEDSGINDLKHYYFMADLADGQPLGRANLYSV
                     CFDLATTDRKLTPAWRTTIKRWFPGFMTFRFLECGLLTMVSNPLALRSDTDLERVLPV
                     LAGQMDQLAHDDGSDFLMIRDVDPEHYQRYLDILRPLGFRPALGFSRVDTTISWSSVE
                     EALGCLSHKRRLPLKTSLEFRERFGIEVEELDEYAEHAPVLARLWRNVKTEAKDYQRE
                     DLNPEFFAACSRHLHGRSRLWLFRYQGTPIAFFLNVWGADENYILLEWGIDRDFEHYR
                     KANLYRAALMLSLKDAISRDKRRMEMGITNYFTKLRIPGARVIPTIYFLRHSTDPVHT
                     ATLARMMMHNIQRPTLPDDMSEEFCRWEERIRLDQDGLPEHDIFRKIDRQHKYTGLKL
                     GGVYGFYPRFTGPQRSTVKAAELGEIVLLGTNSYLGLATHPEVVEASAEATRRYGTGC
                     SGSPLLNGTLDLHVSLEQELACFLGKPAAVLCSTGYQSNLAAISALCESGDMIIQDAL
                     NHRSLFDAARLSGADFTLYRHNDMDHLARVLRRTEGRRRIIVVDAVFSMEGTVADLAT
                     IAELADRHGCRVYVDESHALGVLGPDGRGASAALGVLARMDVVMGTFSKSFASVGGFI
                     AGDRPVVDYIRHNGSGHVFSASLPPAAAAATHAALRVSRREPDRRARVLAAAEYMATG
                     LARQGYQAEYHGTAIVPVILGNPTVAHAGYLRLMRSGVYVNPVAPPAVPEERSGFRTS
                     YLADHRQSDLDRALHVFAGLAEDLTPQGAAL"
     gene            36607..36870
                     /gene="acpA"
                     /locus_tag="Y980_0033"
                     /gene_synonym="acpP"
     CDS             36607..36870
                     /gene="acpA"
                     /locus_tag="Y980_0033"
                     /gene_synonym="acpP"
                     /note="Rv0033, (MTCY10H4.33) Probable acpA (alternate gene
                     name: acpP), acyl carrier protein, similar to others. Also
                     similar to proteins of Mycobacterium tuberculosis Rv1344
                     and Rv2244."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl carrier protein AcpA (ACP)"
                     /protein_id="AJF01376.1"
                     /db_xref="GOA:P71603"
                     /db_xref="InterPro:IPR003231"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="PDB:2CGQ"
                     /db_xref="UniProtKB/TrEMBL:P71603"
                     /translation="MKEAINATIQRILRTDRGITANQVLVDDLGFDSLKLFQLITELE
                     DEFDIAISFRDAQNIKTVGDVYTSVAVWFPETAKPAPLGKGTA"
     gene            36867..37262
                     /locus_tag="Y980_0034"
     CDS             36867..37262
                     /locus_tag="Y980_0034"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0034, (MTCY10H4.34) Conserved hypothetical
                     protein, showing weak similarity to AE001980|AE001980_7
                     hypothetical protein from Deinococcus radiodurans (120
                     aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01377.1"
                     /db_xref="InterPro:IPR009959"
                     /db_xref="UniProtKB/Swiss-Prot:P64673"
                     /translation="MTDDADLDLVRRTFAAFARGDLAELTQCFAPDVEQFVPGKHALA
                     GVFRGVDNVVACLGDTAAAADGTMTVTLEDVLSNTDGQVIAVYRLRASRAGKVLDQRE
                     AILVTVAGGRITRLSEFYADPAATESFWA"
     gene            37259..38947
                     /gene="fadD34"
                     /locus_tag="Y980_0035"
     CDS             37259..38947
                     /gene="fadD34"
                     /locus_tag="Y980_0035"
                     /note="Rv0035, (MTCY10H4.35) Probable
                     fadD34,fatty-acid-CoA synthetase, similar to many."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fatty-acid-CoA ligase FadD34
                     (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)"
                     /protein_id="AJF01378.1"
                     /db_xref="GOA:Q7DAJ8"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="UniProtKB/TrEMBL:Q7DAJ8"
                     /translation="MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAA
                     CIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTR
                     LGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTAT
                     ADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLP
                     LHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWL
                     INAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLA
                     EATVAVSMSAPNTGFRTETHAAAEVVTGGRVLPGYEVRIDAAPGARAGTIKLRGDSVA
                     AKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFII
                     RGESEQHRTKVACFGVNERVVVVLESPLDSIIDKAEADRLRCQVVAATGLQLDELITV
                     RRGAIPTTTSGKLKRRAVAQAYRDGTLPRLATHAWTADPDSAPKTTRSSLEGAH"
     gene            complement(39056..39829)
                     /locus_tag="Y980_0036c"
     CDS             complement(39056..39829)
                     /locus_tag="Y980_0036c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0036c, (MTCY10H4.36c) Conserved protein, highly
                     similar to CAB95889.1|AL359988 conserved hypothetical
                     protein from Streptomyces (276 aa). Also some similarity
                     to Rv3099c|MTCY164_10 (283 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01379.1"
                     /db_xref="GOA:P64675"
                     /db_xref="InterPro:IPR013917"
                     /db_xref="InterPro:IPR017517"
                     /db_xref="InterPro:IPR017518"
                     /db_xref="InterPro:IPR024344"
                     /db_xref="InterPro:IPR027369"
                     /db_xref="UniProtKB/Swiss-Prot:P64675"
                     /translation="MADPGPFVADLRAESDDLDALVAHLPADRWADPTPAPGWTIAHQ
                     IGHLLWTDRVALTAVTDEAGFAELMTAAAANPAGFVDDAATELAAVSPAELLTDWRVT
                     RGRLHEELLAVPDGRKLAWFGPPMSAASMATARLMETWAHGLDVADALGVIRPATQRL
                     RSIAHLGVRTRDYAFIVNNLTPPAEPFLVELRGPSGDTWSWGPSDAAQRVTGSAEDFC
                     FLVTQRRALSTLDVNAVGEDAQRWLTIAQAFAGPPGRGR"
     gene            complement(39877..41202)
                     /locus_tag="Y980_0037c"
     CDS             complement(39877..41202)
                     /locus_tag="Y980_0037c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0037c, (MTCY10H4.37c) Probable conserved integral
                     membrane protein, member of major facilitator superfamily
                     (MFS) possibly involved in transport of macrolide."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved integral membrane protein"
                     /protein_id="AJF01380.1"
                     /db_xref="GOA:P0A5C1"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5C1"
                     /translation="MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQF
                     GDGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRWDRRWVLV
                     GANTGRLALIAGVGTILAVGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVV
                     TMNSVAIASGAVSAFLGANFMLLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGP
                     RVLGPDDTERAIHGSAVYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLI
                     LLLVRHVTARAVGGLGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGALAAAAT
                     IQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDALFWVS
                     YILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTIVGRRGQPVIGR"
     gene            41304..41912
                     /locus_tag="Y980_0038"
     CDS             41304..41912
                     /locus_tag="Y980_0038"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0038, (MTCY10H4.38) Conserved protein, similar to
                     many."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01381.1"
                     /db_xref="GOA:P67757"
                     /db_xref="InterPro:IPR003774"
                     /db_xref="UniProtKB/Swiss-Prot:P67757"
                     /translation="MVAPHEDPEDHVAPAAQRVRAGTLLLANTDLLEPTFRRSVIYIV
                     EHNDGGTLGVVLNRPSETAVYNVLPQWAKLAAKPKTMFIGGPVKRDAALCLAVLRVGA
                     DPEGVPGLRHVAGRLVMVDLDADPEVLAAAVEGVRIYAGYSGWTIGQLEGEIERDDWI
                     VLSALPSDVLVGPRADLWGQVLRRQPLPLSLLATHPIDLSRN"
     gene            complement(42004..42351)
                     /locus_tag="Y980_0039c"
     CDS             complement(42004..42351)
                     /locus_tag="Y980_0039c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0039c, (MTCY21D4.02c, MTCY10H4.39c) Possible
                     conserved transmembrane protein. A core mycobacterial
                     gene; conserved in mycobacterial strains (See Marmiesse et
                     al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01382.1"
                     /db_xref="GOA:P71696"
                     /db_xref="UniProtKB/Swiss-Prot:P71696"
                     /translation="MFLAGVLCMCAAAASALFGSWSLCHTPTADPTALALRAMAPTQL
                     AAAVMLAAGGVVAVAAPGHTALMVVIVCIAGAVGTLAAGSWQSAQYALRRETASPTAN
                     CVGSCAVCTQACH"
     gene            complement(42433..43365)
                     /gene="mtc28"
                     /locus_tag="Y980_0040c"
     CDS             complement(42433..43365)
                     /gene="mtc28"
                     /locus_tag="Y980_0040c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0040c, (MTCY21D4.03c) Mtc28,secreted proline rich
                     28 kDa antigen protein (has hydrophobic stretch at
                     N-terminus) (see citation below). A core mycobacterial
                     gene; conserved in mycobacterial strains (See Marmiesse et
                     al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="Secreted proline rich protein Mtc28 (proline
                     rich 28 kDa antigen)"
                     /protein_id="AJF01383.1"
                     /db_xref="GOA:P0A5Q6"
                     /db_xref="InterPro:IPR019674"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5Q6"
                     /translation="MIQIARTWRVFAGGMATGFIGVVLVTAGKASADPLLPPPPIPAP
                     VSAPATVPPVQNLTALPGGSSNRFSPAPAPAPIASPIPVGAPGSTAVPPLPPPVTPAI
                     SGTLRDHLREKGVKLEAQRPHGFKALDITLPMPPRWTQVPDPNVPDAFVVIADRLGNS
                     VYTSNAQLVVYRLIGDFDPAEAITHGYIDSQKLLAWQTTNASMANFDGFPSSIIEGTY
                     RENDMTLNTSRRHVIATSGADKYLVSLSVTTALSQAVTDGPATDAIVNGFQVVAHAAP
                     AQAPAPAPGSAPVGLPGQAPGYPPAGTLTPVPPR"
     gene            43562..46471
                     /gene="leuS"
                     /locus_tag="Y980_0041"
     CDS             43562..46471
                     /gene="leuS"
                     /locus_tag="Y980_0041"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00178"
                     /note="Rv0041, (MTCY21D4.04) Probable leucyl-tRNA
                     synthetase, similar to many. Contains PS00178
                     Aminoacyl-transfer RNA synthetases class-I signature.
                     Belongs to class-I aminoacyl-tRNA synthetase family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative leucyl-tRNA synthetase LeuS
                     (leucine--tRNA ligase) (LEURS)"
                     /protein_id="AJF01384.1"
                     /db_xref="GOA:P67510"
                     /db_xref="InterPro:IPR001412"
                     /db_xref="InterPro:IPR002302"
                     /db_xref="InterPro:IPR009008"
                     /db_xref="InterPro:IPR009080"
                     /db_xref="InterPro:IPR013155"
                     /db_xref="InterPro:IPR014729"
                     /db_xref="InterPro:IPR015413"
                     /db_xref="InterPro:IPR025709"
                     /db_xref="UniProtKB/Swiss-Prot:P67510"
                     /translation="MTESPTAGPGGVPRADDADSDVPRYRYTAELAARLERTWQENWA
                     RLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYIATDVYARY
                     FRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRR
                     SFSTTDVDFYRWTQWIFLQIYNAWFDTTANKARPISELVAEFESGARCLDGGRDWAKL
                     TAGERADVIDEYRLVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQW
                     MMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEV
                     FTTRPDTLFGATYLVLAPEHDLVDELVAASWPAGVNPLWTYGGGTPGEAIAAYRRAIA
                     AKSDLERQESREKTGVFLGSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRD
                     WDFARAFGLPIVEVIAGGNISESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGR
                     GRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFD
                     PDDADSEPSPPLAKATEWVHVDLDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNS
                     ERFCAKENEAYWMGPRPAEHGPDDPGGVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHV
                     SSREPYRRLVNQGYIQAYAYTDARGSYVPAEQVIERGDRFVYPGPDGEVEVFQEFGKI
                     GKSLKNSVSPDEICDAYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVV
                     DEHTGETRVADGVELDIDTLRALHRTIVGVSEDFAALRNNTATAKLIEYTNHLTKKHR
                     DAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTTSLAHGPFPKADAAYLVDETVEYPV
                     QVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFLAGATPRKVIVVAGRLVNLVI"
     gene            complement(46581..47207)
                     /locus_tag="Y980_0042c"
     CDS             complement(46581..47207)
                     /locus_tag="Y980_0042c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0042c, (MTCY21D4.05c) Possible transcriptional
                     regulatory protein, MarR-family. Some similarity to
                     Mycobacterium tuberculosis proteins Rv2327,Rv0880, and
                     Rv1404."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein
                     (probably MarR-family)"
                     /protein_id="AJF01385.1"
                     /db_xref="GOA:L7N4F5"
                     /db_xref="InterPro:IPR000835"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:L7N4F5"
                     /translation="MSVVRSIGKKMQRISGPNALAVKGRPTQVYGHTHVRLDCRFMAD
                     SEFTAPEVTQLAEGLHRALSKLISMLRRGDPNGAAAGDLTLAQLSILVTLLDQGPIRM
                     TDLAAHERVRTPTTTVAIRRLEKIGLVKRSRDPSDLRAVLVDITPQGRAVHGESLANR
                     RAALAALLSQLPRSDLETLRKALAPLERLASGEPASGPASNSPARKRA"
     gene            complement(47366..48100)
                     /locus_tag="Y980_0043c"
     CDS             complement(47366..48100)
                     /locus_tag="Y980_0043c"
                     /note="Rv0043c, (MTCY21D4.06c) Probable transcriptional
                     regulator, GntR family, similar to others."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein
                     (probably GntR-family)"
                     /protein_id="AJF01386.1"
                     /db_xref="GOA:P67737"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/Swiss-Prot:P67737"
                     /translation="MPKKYGVKEKDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGVS
                     RVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATILEHHELDGLLNGIASARAAANPT
                     PRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYAGPRLHATIRASQNLIPRVF
                     WMTYQNSRDDVLPFYEEENAAIHRREPEAARAACIGRSELMAQTMLAELFRRRVLVPP
                     EGACPGPFGAPIPGFARSYQPSSPVP"
     gene            complement(48233..49027)
                     /locus_tag="Y980_0044c"
     CDS             complement(48233..49027)
                     /locus_tag="Y980_0044c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0044c, (MTCY21D4.07c) Possible oxidoreductase,
                     highly similar to AAD32732.1|MmcI|AF127374| F420-dependent
                     H4MPT reductase from Streptomyces lavendulae (264 aa).
                     Also similar to Mycobacterium tuberculosis proteins e.g.
                     Rv1855c, Rv0953c, Rv0791c, Rv0132c, etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01387.1"
                     /db_xref="GOA:L7N5Z1"
                     /db_xref="InterPro:IPR011251"
                     /db_xref="InterPro:IPR022480"
                     /db_xref="UniProtKB/TrEMBL:L7N5Z1"
                     /translation="MTSLVRPDLPVRIGVQLQPQHAPHYRAVRDAVRRCEDIGVDIAF
                     TWDHFFPLYGDPDGPHFECWTVLGAWAEQTSHIEIGALVTCNSYRNPELLADMARTVD
                     HISGGRLILGIGSGWKQKDYDEYGYRFGTAGSRLDDLAAALPRIKARLGKLNPPPTRD
                     IPVLIGGGGERKTLRLVAEYADIWHSFTAGDSYLAKSAVLSTHCSTVGRNPATIERSA
                     AVDGGGLIASAEALAGLGVTLLTVGCDGPDYDLSAAAALCRWRDGR"
     gene            complement(49043..49939)
                     /locus_tag="Y980_0045c"
     CDS             complement(49043..49939)
                     /locus_tag="Y980_0045c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0045c, (MTCY21D4.08c) Possible hydrolase, showing
                     similarity with others. Also similar to Mycobacterium
                     tuberculosis proteins Rv3473c, Rv1123c,Rv1938, Rv3617,
                     Rv3670, etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative hydrolase"
                     /protein_id="AJF01388.1"
                     /db_xref="GOA:P71702"
                     /db_xref="InterPro:IPR000073"
                     /db_xref="PDB:3P2M"
                     /db_xref="UniProtKB/TrEMBL:P71702"
                     /translation="MLSDDELTGLDEFALLAENAEQAGVNGPLPEVERVQAGAISALR
                     WGGSAPRVIFLHGGGQNAHTWDTVIVGLGEPALAVDLPGHGHSAWREDGNYSPQLNSE
                     TLAPVLRELAPGAEFVVGMSLGGLTAIRLAAMAPDLVGELVLVDVTPSALQRHAELTA
                     EQRGTVALMHGEREFPSFQAMLDLTIAAAPHRDVKSLRRGVFHNSRRLDNGNWVWRYD
                     AIRTFGDFAGLWDDVDALSAPITLVRGGSSGFVTDQDTAELHRRATHFRGVHIVEKSG
                     HSVQSDQPRALIEIVRGVLDTR"
     gene            complement(50021..51124)
                     /gene="ino1"
                     /locus_tag="Y980_0046c"
                     /gene_synonym="tbINO"
     CDS             complement(50021..51124)
                     /gene="ino1"
                     /locus_tag="Y980_0046c"
                     /gene_synonym="tbINO"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0046c, (MTCY21D4.09c) Ino1 (alternate gene name:
                     tbINO), myo-inositol-1-phosphate synthase (see citations
                     below)."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inositol-1-phosphate synthase Ino1 (inositol
                     1-phosphate synthetase) (D-glucose 6-phosphate
                     cycloaldolase) (glucose 6-phosphate cyclase)
                     (glucocycloaldolase)"
                     /protein_id="AJF01389.1"
                     /db_xref="GOA:P71703"
                     /db_xref="InterPro:IPR002587"
                     /db_xref="InterPro:IPR013021"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017815"
                     /db_xref="PDB:1GR0"
                     /db_xref="UniProtKB/Swiss-Prot:P71703"
                     /translation="MSEHQSLPAPEASTEVRVAIVGVGNCASSLVQGVEYYYNADDTS
                     TVPGLMHVRFGPYHVRDVKFVAAFDVDAKKVGFDLSDAIFASENNTIKIADVAPTNVI
                     VQRGPTLDGIGKYYADTIELSDAEPVDVVQALKEAKVDVLVSYLPVGSEEADKFYAQC
                     AIDAGVAFVNALPVFIASDPVWAKKFTDARVPIVGDDIKSQVGATITHRVLAKLFEDR
                     GVQLDRTMQLNVGGNMDFLNMLERERLESKKISKTQAVTSNLKREFKTKDVHIGPSDH
                     VGWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVWDSPNSAGVIIDAVRAAKIAKDRGIG
                     GPVIPASAYLMKSPPEQLPDDIARAQLEEFIIG"
     gene            complement(51185..51727)
                     /locus_tag="Y980_0047c"
     CDS             complement(51185..51727)
                     /locus_tag="Y980_0047c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0047c, (MTCY21D4.10c) Conserved protein, similar
                     to many."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01390.1"
                     /db_xref="InterPro:IPR005149"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:L0T291"
                     /translation="MLELAILGLLIESPMHGYELRKRLTGLLGAFRAFSYGSLYPALR
                     RMQADGLIAENAAPAGTPVRRARRVYQLTDKGRRRFGELVADTGPHNYTDDGFGVHLA
                     FFNRTPAEARMRILEGRRRQVEERREGLREAVARASSSFDRYTRQLHQLGLESSEREV
                     KWLNELIAAERAAPNPAEQT"
     gene            complement(51828..52697)
                     /locus_tag="Y980_0048c"
     CDS             complement(51828..52697)
                     /locus_tag="Y980_0048c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0048c, MTCY21D4.11c Possible membrane protein."
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane protein"
                     /protein_id="AJF01391.1"
                     /db_xref="GOA:P71705"
                     /db_xref="InterPro:IPR012551"
                     /db_xref="UniProtKB/Swiss-Prot:P71705"
                     /translation="MAKWLGAPLARGVSTATRAKDSDRQDACRILDDALRDGELSMEE
                     HRERVSAATKAVTLGDLQRLVADLQVESAPAQMPALKSRAKRTELGLLAAAFVASVLL
                     GVGIGWGVYGNTRSPLDFTSDPGAKPDGIAPVVLTPPRQLHSLGGLTGLLEQTRKRFG
                     DTMGYRLVIYPEYASLDRVDPADDRRVLAYTYRGGWGDATSSAKSIADVSVVDLSKFD
                     AKTAVGIMRGAPETLGLKQSDVKSMYLIVEPVKDPTTPAALSLSLYVSSDYGGGYLVF
                     AGDGTIKHVSYPS"
     gene            52831..53244
                     /locus_tag="Y980_0049"
     CDS             52831..53244
                     /locus_tag="Y980_0049"
                     /note="Rv0049, (MTCY21D4.12) Conserved hypothetical
                     protein. A core mycobacterial gene; conserved in
                     mycobacterial strains (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01392.1"
                     /db_xref="UniProtKB/Swiss-Prot:P64677"
                     /translation="MDYTLRRRSLLAEVYSGRTGVSEVCDANPYLLRAAKFHGKPSRV
                     ICPICRKEQLTLVSWVFGEHLGAVSGSARTAEELILLATRFSEFAVHVVEVCRTCSWN
                     HLVKSYVLGAARPARPPRGSGGTRTARNGARTASE"
     gene            53663..55696
                     /gene="ponA1"
                     /locus_tag="Y980_0050"
     CDS             53663..55696
                     /gene="ponA1"
                     /locus_tag="Y980_0050"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0050, (MTCY21D4.13) Probable
                     ponA1,penicillin-binding protein (class A), bienzymatic
                     protein with transglycosylase and transpeptidase
                     activities (see Graham & Clark-Curtiss 1999), highly
                     similar to many (see Billman-Jacobe et al., 1999). Belongs
                     to the transglycosylase family in the N-terminal section,
                     and to the transpeptidase family in the C-terminal
                     section."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional penicillin-binding protein
                     1A/1B PonA1 (murein polymerase) (PBP1):
                     penicillin-insensitive transglycosylase (peptidoglycan
                     TGASE) + penicillin-sensitive transpeptidase
                     (DD-transpeptidase)"
                     /protein_id="AJF01393.1"
                     /db_xref="GOA:P71707"
                     /db_xref="InterPro:IPR001264"
                     /db_xref="InterPro:IPR001460"
                     /db_xref="InterPro:IPR012338"
                     /db_xref="UniProtKB/Swiss-Prot:P71707"
                     /translation="MVILLPMVTFTMAYLIVDVPKPGDIRTNQVSTILASDGSEIAKI
                     VPPEGNRVDVNLSQVPMHVRQAVIAAEDRNFYSNPGFSFTGFARAVKNNLFGGDLQGG
                     STITQQYVKNALVGSAQHGWSGLMRKAKELVIATKMSGEWSKDDVLQAYLNIIYFGRG
                     AYGISAASKAYFDKPVEQLTVAEGALLAALIRRPSTLDPAVDPEGAHARWNWVLDGMV
                     ETKALSPNDRAAQVFPETVPPDLARAENQTKGPNGLIERQVTRELLELFNIDEQTLNT
                     QGLVVTTTIDPQAQRAAEKAVAKYLDGQDPDMRAAVVSIDPHNGAVRAYYGGDNANGF
                     DFAQAGLQTGSSFKVFALVAALEQGIGLGYQVDSSPLTVDGIKITNVEGEGCGTCNIA
                     EALKMSLNTSYYRLMLKLNGGPQAVADAAHQAGIASSFPGVAHTLSEDGKGGPPNNGI
                     VLGQYQTRVIDMASAYATLAASGIYHPPHFVQKVVSANGQVLFDASTADNTGDQRIPK
                     AVADNVTAAMEPIAGYSRGHNLAGGRDSAAKTGTTQFGDTTANKDAWMVGYTPSLSTA
                     VWVGTVKGDEPLVTASGAAIYGSGLPSDIWKATMDGALKGTSNETFPKPTEVGGYAGV
                     PPPPPSEVPPSETVIQPTVEIAPGITIPIGPPTTITLAPPPPAPPAATPTPPP"
     gene            55693..57375
                     /locus_tag="Y980_0051"
     CDS             55693..57375
                     /locus_tag="Y980_0051"
                     /note="Rv0051, (MTCY21D4.14) Predicted to be in the GT-C
                     superfamily of glycosyltransferases (See Liu and
                     Mushegian, 2003). Probable conserved transmembrane
                     protein."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01394.1"
                     /db_xref="GOA:L0T463"
                     /db_xref="InterPro:IPR016570"
                     /db_xref="InterPro:IPR018584"
                     /db_xref="UniProtKB/TrEMBL:L0T463"
                     /translation="MTGALSQSSNISPLPLAADLRSADNRDCPSRTDVLGAALANVVG
                     GPVGRHALIGRTRLMTPLRVMFAIALVFLALGWSTKAACLQSTGTGPGDQRVANWDNQ
                     RAYYQLCYSDTVPLYGAELLSQGKFPYKSSWIETDSNGTPQLRYDGQIAVRYMEYPVL
                     TGIYQYLSMAIAKTYTALSKVAPLPVVAEVVMFFNVAAFGLALAWLTTVWATSGLAGR
                     RIWDAALVAASPLVIFQIFTNFDALATGLATSGLLAWARRRPVLAGVLIGLGSAAKLY
                     PLLFLYPLLLLGIRAGRLNALARTMAAAAATWLLVNLPVMLLFPRGWSEFFRLNTRRG
                     DDMDSLYNVVKSFTGWRGFDPTLGFWEPPLVLNTVVTLLFVLCCAAIAYIALTAPHRP
                     RVAQLTFLTVASFLLVNKVWSPQFSLWLVPLAVLALPHRRILLAWMTIDALVWVPRMY
                     YLYGNPSRSLPEQWFTTTVLLRDIAVMVLCGLVVWQIYRPGRDLVRTGGPGALPACGG
                     VDDPVGGVFANAADAPPGRLPSWLRPRLGDEHARERTPDAGRDRTFSGQHRA"
     gene            57407..57970
                     /locus_tag="Y980_0052"
     CDS             57407..57970
                     /locus_tag="Y980_0052"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0052, (MTCY21D4.15) Conserved protein, similar to
                     others including Rv1930c from Mycobacterium tuberculosis
                     (174 aa). May be a membrane protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01395.1"
                     /db_xref="InterPro:IPR025628"
                     /db_xref="UniProtKB/TrEMBL:L0T298"
                     /translation="MPSFDVVFVGHRRGEVRSDNAMLGLLCDAAFDELTRPDVVIFPG
                     GIGTRTLIHDQTVLDWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLF
                     NSLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQ
                     PPVDAGSLAKASPATHRLALEFYQHRL"
     gene            58189..58479
                     /gene="rpsF"
                     /locus_tag="Y980_0053"
     CDS             58189..58479
                     /gene="rpsF"
                     /locus_tag="Y980_0053"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS01048"
                     /note="Rv0053, (MTCY21D4.16) rpsF, 30S ribosomal protein
                     S6, highly similar to many. Contains PS01048 Ribosomal
                     protein S6 signature. Belongs to the S6P family of
                     ribosomal proteins."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6 RpsF"
                     /protein_id="AJF01396.1"
                     /db_xref="GOA:P66591"
                     /db_xref="InterPro:IPR000529"
                     /db_xref="InterPro:IPR014717"
                     /db_xref="InterPro:IPR020814"
                     /db_xref="InterPro:IPR020815"
                     /db_xref="UniProtKB/Swiss-Prot:P66591"
                     /translation="MRPYEIMVILDPTLDERTVAPSLETFLNVVRKDGGKVEKVDIWG
                     KRRLAYEIAKHAEGIYVVIDVKAAPATVSELDRQLSLNESVLRTKVMRTDKH"
     gene            58583..59077
                     /gene="ssb"
                     /locus_tag="Y980_0054"
     CDS             58583..59077
                     /gene="ssb"
                     /locus_tag="Y980_0054"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0054, (MTCY21D4.17) ssb,single-strand binding
                     protein (see Mizrahi & Andersen 1998), highly similar to
                     others. Belongs to the SSB family."
                     /codon_start=1
                     /transl_table=11
                     /product="Single-strand binding protein Ssb
                     (helix-destabilizing protein)"
                     /protein_id="AJF01397.1"
                     /db_xref="GOA:P0A610"
                     /db_xref="InterPro:IPR000424"
                     /db_xref="InterPro:IPR011344"
                     /db_xref="InterPro:IPR012340"
                     /db_xref="PDB:1UE1"
                     /db_xref="PDB:1UE5"
                     /db_xref="PDB:1UE6"
                     /db_xref="PDB:1UE7"
                     /db_xref="UniProtKB/Swiss-Prot:P0A610"
                     /translation="MAGDTTITIVGNLTADPELRFTPSGAAVANFTVASTPRIYDRQT
                     GEWKDGEALFLRCNIWREAAENVAESLTRGARVIVSGRLKQRSFETREGEKRTVIEVE
                     VDEIGPSLRYATAKVNKASRSGGFGSGSRPAPAQTSSASGDDPWGSAPASGSFGGGDD
                     EPPF"
     gene            59119..59373
                     /gene="rpsR1"
                     /locus_tag="Y980_0055"
                     /gene_synonym="rpsR"
     CDS             59119..59373
                     /gene="rpsR1"
                     /locus_tag="Y980_0055"
                     /gene_synonym="rpsR"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0055, (MTCY21D4.18) rpsR1, 30S ribosomal protein
                     S18-1. Belongs to the S18P family of ribosomal proteins.
                     Note that previously known as rpsR."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18-1 RpsR1"
                     /protein_id="AJF01398.1"
                     /db_xref="GOA:P69230"
                     /db_xref="InterPro:IPR001648"
                     /db_xref="InterPro:IPR018275"
                     /db_xref="UniProtKB/Swiss-Prot:P69230"
                     /translation="MAKSSKRRPAPEKPVKTRKCVFCAKKDQAIDYKDTALLRTYISE
                     RGKIRARRVTGNCVQHQRDIALAVKNAREVALLPFTSSVR"
     gene            59406..59864
                     /gene="rplI"
                     /locus_tag="Y980_0056"
     CDS             59406..59864
                     /gene="rplI"
                     /locus_tag="Y980_0056"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00651"
                     /note="Rv0056, (MTCY21D4.19) rplI, 50S ribosomal protein
                     L9. Contains PS00651 Ribosomal protein L9 signature.
                     Belongs to the L9P family of ribosomal proteins."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9 RplI"
                     /protein_id="AJF01399.1"
                     /db_xref="GOA:P66315"
                     /db_xref="InterPro:IPR000244"
                     /db_xref="InterPro:IPR000644"
                     /db_xref="InterPro:IPR009027"
                     /db_xref="InterPro:IPR020069"
                     /db_xref="InterPro:IPR020070"
                     /db_xref="InterPro:IPR020594"
                     /db_xref="UniProtKB/Swiss-Prot:P66315"
                     /translation="MKLILTADVDHLGSIGDTVEVKDGYGRNFLLPRGLAIVASRGAQ
                     KQADEIRRARETKSVRDLEHANEIKAAIEALGPIALPVKTSADSGKLFGSVTAADVVA
                     AIKKAGGPNLDKRIVRLPKTHIKAVGTHFVSVHLHPEIDVEVSLDVVAQS"
     gene            59893..60414
                     /locus_tag="Y980_0057"
     CDS             59893..60414
                     /locus_tag="Y980_0057"
                     /note="Rv0057, (MTCY21D4.20) Hypothetical unknown
                     protein."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /protein_id="AJF01400.1"
                     /db_xref="UniProtKB/Swiss-Prot:P64679"
                     /translation="MPVVTAVGRRRGFAMPWVSTARSGAVMLANYSAGVCGRVSSPGL
                     NVRKMCLKANTPGAVTWLDTPKRFLSTQTASRCMAVNSSDVVTGRIDPQVLHTPLNTD
                     VDGYAHAMHSSINSGPLEYLPATFSVFPALGDVGDLGGGVGAATYALDRLSNMRSGAC
                     VGGGESPWRSLMT"
     gene            60393..63017
                     /gene="dnaB"
                     /locus_tag="Y980_0058"
     CDS             60393..63017
                     /gene="dnaB"
                     /locus_tag="Y980_0058"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00017"
                     /note="Rv0058, (MTV030.01, MTCY21D4.21) Probable dnaB,
                     replicative DNA helicase. Contains an intein (position
                     61630..62838) similar to, and in the same position as,
                     those in Sycnechocystis and Rhodothermus marinus (see
                     citation below) and C-terminal extein (position
                     62839..63015) similar to many dnaB proteins. This protein
                     undergoes a protein self splicing that involves a
                     post-translational excision of the intervening region
                     (intein) followed by peptide ligation. Belongs to the
                     helicase family, DNAB subfamily. In the intein section;
                     belongs to the homing endonuclease family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative replicative DNA helicase DnaB"
                     /protein_id="AJF01401.1"
                     /db_xref="GOA:P71715"
                     /db_xref="InterPro:IPR003586"
                     /db_xref="InterPro:IPR003587"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR004042"
                     /db_xref="InterPro:IPR006141"
                     /db_xref="InterPro:IPR006142"
                     /db_xref="InterPro:IPR007692"
                     /db_xref="InterPro:IPR007693"
                     /db_xref="InterPro:IPR007694"
                     /db_xref="InterPro:IPR016136"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR027434"
                     /db_xref="PDB:2R5U"
                     /db_xref="UniProtKB/Swiss-Prot:P71715"
                     /translation="MAVVDDLAPGMDSSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDA
                     IADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLRRIGGAPY
                     LHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYAGAEGADVAEVVDRAQ
                     AEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSGGLARGVATGFTELDEVTNGLHP
                     GQMVIVAARPGVGKSTLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKL
                     SDMRSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKANLKLIV
                     VDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLNRGPEQRTDKKPML
                     ADLRESGCLTASTRILRADTGAEVAFGELMRSGERPMVWSLDERLRMVARPMINVFPS
                     GRKEVFRLRLASGREVEATGSHPFMKFEGWTPLAQLKVGDRIAAPRRVPEPIDTQRMP
                     ESELISLARMIGDGSCLKNQPIRYEPVDEANLAAVTVSAAHSDRAAIRDDYLAARVPS
                     LRPARQRLPRGRCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAG
                     GSVRWDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWRLHIHG
                     AKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVWAQVRNRLSAKQMM
                     DIQLHEPTMWKHSPSRSRPHRAEARIEDRAIHELARGDAYWDTVVEITSIGDQHVFDG
                     TVSGTHNFVANGISLHNSLEQDADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTK
                     TVTVAHQLHLSRFANMAR"
     gene            63197..63889
                     /locus_tag="Y980_0059"
     CDS             63197..63889
                     /locus_tag="Y980_0059"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0059, (MTV030.02) Hypothetical unknown protein."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /protein_id="AJF01402.1"
                     /db_xref="UniProtKB/TrEMBL:L7N4F6"
                     /translation="MITRYKPESGFVARSGGPDRKRPHDWIVWHFTHADNLPGIITAG
                     RLLADSAVTPTTEVAYNPVKELRRHKVVAPDSRYPASMASDHVPFYIAARSPMLYVVC
                     KGHSGYSGGAGPLVHLGVALGDIIDADLTWCASDGNAAASYTKFSRQVDTLGTFVDFD
                     LLCQRQWHNTDDDPNRQSRRAAEILVYGHVPFELVSYVCCYNTETMTRVRTLLDPVGG
                     VRKYVIKPGMYY"
     gene            63906..64964
                     /locus_tag="Y980_0060"
     CDS             63906..64964
                     /locus_tag="Y980_0060"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0060, (MTV030.03) Conserved hypothetical
                     protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01403.1"
                     /db_xref="InterPro:IPR002589"
                     /db_xref="UniProtKB/TrEMBL:L7N5R6"
                     /translation="MITYGSGDLLRADTEALVNTVNCVGVMGKGIALQFKRRYPEMFT
                     AYEKACKRGEVTIGKMFVVDTGQLDGPKHIINFPTKKHWRAPSKLAYIDAGLIDLIRV
                     IRELNIASVAVPPLGVGNGGLDWEDVEQRLVSAFQQLPDVDAVIYPPSGGSRAIEGVE
                     GLRMTWGRAVILEAMRRYLQQRRAMEPWEDPAGISHLEIQKLMYFANEADPDLALDFT
                     PGRYGPYSERVRHLLQGMEGAFTVGLGDGTARVLANQPISLTTKGTDAITDYLATDAA
                     ADRVSAAVDTVLRVIEGFEGPYGVELLASTHWVATREGAKEPATAAAAVRKWTKRKGR
                     IYSDDRIGVALDRILMTA"
     gene            complement(65009..65347)
                     /locus_tag="Y980_0061c"
     CDS             complement(65009..65347)
                     /locus_tag="Y980_0061c"
                     /note="Rv0061c Conserved hypothetical protein supported by
                     RNA-seq data. Similar to MMAR_3839, 76% identity in 112 aa
                     overlap. Replaces questionable ORF Rv0061 (MTV030.04)."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /protein_id="AJF01404.1"
                     /db_xref="UniProtKB/TrEMBL:L0T472"
                     /translation="MKLKFARLSTAILGCAAALVFPASVASADPPDPHQPDMTKGYCP
                     GGRWGFGDLAVCDGEKYPDGSFWHQWMQTWFTGPQFYFDCVSGGEPLPGPPPPGGCGG
                     AIPSEQPNAP"
     gene            65549..66691
                     /gene="celA1"
                     /locus_tag="Y980_0062"
                     /gene_synonym="cel6"
                     /gene_synonym="celA"
     CDS             65549..66691
                     /gene="celA1"
                     /locus_tag="Y980_0062"
                     /gene_synonym="cel6"
                     /gene_synonym="celA"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0062, (MTV030.05) Possible celA1,cellulase,
                     similar to many. Seems to belong to cellulase family B
                     (family 6 of glycosyl hydrolases). Note that previously
                     known as celA."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cellulase CelA1 (endoglucanase)
                     (endo-1,4-beta-glucanase) (FI-cmcase) (carboxymethyl
                     cellulase)"
                     /protein_id="AJF01405.1"
                     /db_xref="GOA:Q79G13"
                     /db_xref="InterPro:IPR016288"
                     /db_xref="PDB:1UOZ"
                     /db_xref="PDB:1UP0"
                     /db_xref="PDB:1UP2"
                     /db_xref="PDB:1UP3"
                     /db_xref="UniProtKB/TrEMBL:Q79G13"
                     /translation="MTRRTGQRWRGTLPGRRPWTRPAPATCRRHLAFVELRHYFARVM
                     SSAIGSVARWIVPLLGVAAVASIGVIADPVRVVRAPALILVDAANPLAGKPFYVDPAS
                     AAMVAARNANPPNAELTSVANTPQSYWLDQAFPPATVGGTVARYTGAAQAAGAMPVLT
                     LYGIPHRDCGSYASGGFATGTDYRGWIDAVASGLGSSPATIIVEPDALAMADCLSPDQ
                     RQERFDLVRYAVDTLTRDPAAAVYVDAGHSRWLSAEAMAARLNDVGVGRARGFSLNVS
                     NFYTTDEEIGYGEAISGLTNGSHYVIDTSRNGAGPAPDAPLNWCNPSGRALGAPPTTA
                     TAGAHADAYLWIKRPGESDGTCGRGEPQAGRFVSQYAIDLAHNAGQ"
     gene            66920..68359
                     /locus_tag="Y980_0063"
     CDS             66920..68359
                     /locus_tag="Y980_0063"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00862"
                     /note="Rv0063, (MTV030.06) Possible oxidoreductase,
                     similar to many. Similar to Mycobacterium tuberculosis
                     proteins e.g. Rv3107c, Rv1257c, etc. Contains PS00862
                     Oxygen oxidoreductases covalent FAD-binding site."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01406.1"
                     /db_xref="GOA:L7N4J5"
                     /db_xref="InterPro:IPR006093"
                     /db_xref="InterPro:IPR006094"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="InterPro:IPR012951"
                     /db_xref="InterPro:IPR016166"
                     /db_xref="InterPro:IPR016167"
                     /db_xref="InterPro:IPR016169"
                     /db_xref="UniProtKB/TrEMBL:L7N4J5"
                     /translation="MAREISRQTFLRGAAGALAAGAVFGSVRATADPAASGWEALSSA
                     LGGKVLQPDDGPQFATAKQVFNTNYNGYTPAVIVTPTSQLDVQKAMAFAAANNLKVAP
                     RGGGHSYVGASTANGAMVLDLRQLPGDINYDATTGRVTVTPATGLYAMHQVLAAAGRG
                     IPTGTCPTVGVAGHALGGGLGANSRHAGLLCDQLTSASVVLPSGQAVTASATDHPDLF
                     WALRGGGGGNFGVTTSLTFATFPSGDLDVVNLNFPPQSFAQVLVGWQNWLRTADRGSW
                     ALADATVDPLGTHCRILATCPAGSGGSVAAAIVSAVGTQPTGTENHTFNYLDLVRYLA
                     VGNLNPSPLGYVGGSDVFTTITPATAQGIASAVDAFPRGAGRMLAIMHALDGALATVS
                     PGATAFPWRRQSALVQWYVETSGSPSEATSWLNTAHQAVRAYSVGGYVNYLEVNQPPA
                     RYFGPNLSRLSAVRQKYDPSRVMFSGLNF"
     gene            68617..71556
                     /locus_tag="Y980_0064"
     CDS             68617..71556
                     /locus_tag="Y980_0064"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0064, (MTV030.07) Probable conserved
                     transmembrane protein, similar to many. Contains probable
                     coiled-coil domain from aa 948 to 976."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane protein"
                     /protein_id="AJF01407.1"
                     /db_xref="GOA:O53609"
                     /db_xref="InterPro:IPR005372"
                     /db_xref="UniProtKB/Swiss-Prot:O53609"
                     /translation="METGSPGKRPVLPKRARLLVTAGMGMLALLLFGPRLVDIYVDWL
                     WFGEVGFRSVWITVLLTRLAIVAAVALVVAGIVLAALLLAYRSRPFFVPDEPQRDPVA
                     PLRSAVMRRPRLFGWGIAVTLGVVCGLIASFDWVKVQLFVHGGTFGIVDPEFGYDIGF
                     FVFDLPFYRSVLNWLFVAVVLAFLASLLTHYLFGGLRLTTGRGMLTQAARVQLAVFAG
                     AVVLLKAVAYWLDRYELLSSGRKEPTFTGAGYTDIHAELPAKLVLVAIAVLCAVSFFT
                     AIFLRDLRIPAMAAALLVLSAILVGGLWPLLMEQFSVRPNAADVERPYIQRNIEATRE
                     AYRIGGDWVQYRSYPGIGTKQPRDVPVDVTTIAKVRLLDPHILSRTFTQQQQLKNFFS
                     FAEILDIDRYRIDGELQDYIVGVRELSPKSLTGNQTDWINKHTVYTHGNGFVAAPANR
                     VNAAARDAENISDSNSGYPIYAVSDIASLGSGRQVIPVEQPRVYYGEVIAQADPDYAI
                     VGGAPGSAPREYDTDTSKYTYTGAGGVSIGNWFNRTVFATKVAQHKFLFSREIGSESK
                     VLIHRDPKERVQRVAPWLTTDDNPYPVVVNGRIVWIVDAYTTLDTYPYAQRSSLEGPV
                     TSPTGIVRQGKQVSYVRNSVKATVDAYDGTVTLFQFDRDDPVLRTWMRAFPGTVKSED
                     QIPDELRAHFRYPEDLFEVQRSLLAKYHVDEPREFFTTNAFWSVPSDPTNNANATQPP
                     FYVLVGDQQSAQPSFRLASAMVGYNREFLSAYISAHSDPANYGKLTVLELPTDTLTQG
                     PQQIQNSMISDTRVASERTLLERSNRIHYGNLLSLPIADGGVLYVEPLYTERISTSPS
                     SSTFPQLSRVLVSVREPRTEGGVRVGYAPTLAESLDQVFGPGTGRVATARGGDAASAP
                     PPGAGGPAPPQAVPPPRTTQPPAAPPRGPDVPPATVAELRETLADLRAVLDRLEKAID
                     AAETPGG"
     gene            71586..71825
                     /gene="vapB1"
                     /locus_tag="Y980_0064A"
     CDS             71586..71825
                     /gene="vapB1"
                     /locus_tag="Y980_0064A"
                     /note="Rv0064A Possible vapB1, antitoxin, part of
                     toxin-antitoxin (TA) operon with Rv0065 (See Arcus et al.,
                     2005; Pandey and Gerdes, 2005). Weakly similar to others
                     in Mycobacterium tuberculosis e.g. Rv0300 (73 aa),Rv1721c
                     (75 aa)"
                     /codon_start=1
                     /transl_table=11
                     /product="putative antitoxin VapB1"
                     /protein_id="AJF01408.1"
                     /db_xref="GOA:P0CW29"
                     /db_xref="InterPro:IPR010985"
                     /db_xref="UniProtKB/Swiss-Prot:P0CW29"
                     /translation="MATIQVRDLPEDVAETYRRRATAAGQSLQTYMRTKLIEGVRGRD
                     KAEAIEILEQALASTASPGISRETIEASRRELRGG"
     gene            71818..72219
                     /gene="vapC1"
                     /locus_tag="Y980_0065"
     CDS             71818..72219
                     /gene="vapC1"
                     /locus_tag="Y980_0065"
                     /note="Rv0065, (MTV030.08) Possible vapC1,toxin, part of
                     toxin-antitoxin (TA) operon with Rv0064A,contains PIN
                     domain (See Arcus et al., 2005; Pandey and Gerdes, 2005).
                     Similar to several others in Mycobacterium tuberculosis:
                     Rv0960 (127 aa), Rv1720c (129 aa), and Rv0549c (137 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative toxin VapC1"
                     /protein_id="AJF01409.1"
                     /db_xref="GOA:O53610"
                     /db_xref="InterPro:IPR002716"
                     /db_xref="InterPro:IPR022907"
                     /db_xref="UniProtKB/Swiss-Prot:O53610"
                     /translation="MDECVVDAAAVVDALAGKGASAIVLRGLLKESISNAPHLLDAEV
                     GHALRRAVLSDEISEEQARAALDALPYLIDNRYPHSPRLIEYTWQLRHNVTFYDALYV
                     ALATALDVPLLTGDSRLAAAPGLPCEIKLVR"
     gene            complement(72271..74508)
                     /gene="icd2"
                     /locus_tag="Y980_0066c"
     CDS             complement(72271..74508)
                     /gene="icd2"
                     /locus_tag="Y980_0066c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0066c, (MTV030.09c) Probable icd2,isocitrate
                     dehydrogenase NADP-dependent. Belongs to the
                     monomeric-type family of IDH. Note that in H37Rv, Rv0066c
                     is named icd2 and Rv3339c is icd1 while in CDC1551 and
                     Erdman strains, Rv0066c is icd1 and Rv3339c is icd2."
                     /codon_start=1
                     /transl_table=11
                     /product="putative isocitrate dehydrogenase [NADP] Icd2
                     (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH)
                     (IDP)"
                     /protein_id="AJF01410.1"
                     /db_xref="GOA:L7N5H0"
                     /db_xref="InterPro:IPR004436"
                     /db_xref="InterPro:IPR024084"
                     /db_xref="UniProtKB/TrEMBL:L7N5H0"
                     /translation="MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDI
                     SVAARILAEFPDYLTEEQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKEL
                     QDKGYAVPDYPADPKTDQEKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKH
                     PHSMGEWSMASRTHVAHMRHGDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPL
                     DDGDVIDSMFMSKKALCDFYEEQMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIF
                     YKDAFAKHQELFDDLGVNVNNGLSDLYSKIESLPASQRDEIIEDLHRCHEHRPELAMV
                     DSARGISNFHSPSDVIVDASMPAMIRAGGKMYGADGKLKDTKAVNPESTFSRIYQEII
                     NFCKTNGQFDPTTMGTVPNVGLMAQQAEEYGSHDKTFEIPEDGVANIVDVATGEVLLT
                     ENVEAGDIWRMCIVKDAPIRDWVKLAVTRARISGMPVLFWLDPYRPHENELIKKVKTY
                     LKDHDTEGLDIQIMSQVRSMRYTCERLVRGLDTIAATGNILRDYLTDLFPILELGTSA
                     KMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEENHLRWDSLGEFLALGAGFEDIGIKT
                     GNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNRGSQFYLAMYWAQELAAQTDDQQ
                     LAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYAPDSDMTTAVMRPSKTFNAAL
                     EAVQG"
     gene            complement(74626..75195)
                     /locus_tag="Y980_0067c"
     CDS             complement(74626..75195)
                     /locus_tag="Y980_0067c"
                     /note="Rv0067c, (MTV030.10c) Possible transcriptional
                     regulator, highly similar to many. Contains probable
                     helix-turn-helix motif from aa 34 to 55 (Score 1523, +4.37
                     SD)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein
                     (possibly TetR-family)"
                     /protein_id="AJF01411.1"
                     /db_xref="GOA:L7N554"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:L7N554"
                     /translation="MAPTDRRVRADAARNRARVLEVAYQTFAADGLSVPVDEIARRAG
                     VGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHPGDALFAFLRSMVLQWGA
                     TDRGLVEALAGVGIEISSAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLV
                     GCQAMQSYNAELAAKVTDVALDGLRANRK"
     gene            75298..76209
                     /locus_tag="Y980_0068"
     CDS             75298..76209
                     /locus_tag="Y980_0068"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0068, (MTV030.11) Probable oxidoreductase,
                     similar to many."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01412.1"
                     /db_xref="GOA:L0T5L1"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:L0T5L1"
                     /translation="MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVLA
                     VRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQRIDLLINNAG
                     VMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGSRVVTISSVGHRIRAAIH
                     FDDLQWERRYRRVAAYGQAKLANLLFTYELQRRLAPGGTTIAVASHPGVSNTEVVRNM
                     PRPLVAVAAILAPLMQDAELGALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASS
                     AQSHDEQLQRRLWAVSEELTGVVYPVG"
     gene            complement(76234..77619)
                     /gene="sdaA"
                     /locus_tag="Y980_0069c"
     CDS             complement(76234..77619)
                     /gene="sdaA"
                     /locus_tag="Y980_0069c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0069c, (MTV030.12c) Probable sdaA,L-serine
                     dehydratase. Belongs to the iron-sulfur dependent L-serine
                     dehydratase family. Cofactor: iron-sulfur (4FE-4S)
                     (probable)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative L-serine dehydratase SdaA (L-serine
                     deaminase) (SDH) (L-SD)"
                     /protein_id="AJF01413.1"
                     /db_xref="GOA:P66773"
                     /db_xref="InterPro:IPR004644"
                     /db_xref="InterPro:IPR005130"
                     /db_xref="InterPro:IPR005131"
                     /db_xref="UniProtKB/Swiss-Prot:P66773"
                     /translation="MTISVFDLFTIGIGPSSSHTVGPMRAANQFVVALRRRGHLDDLE
                     AMRVDLFGSLAATGAGHGTMSAILLGLEGCQPETITTEHKERRLAEIAASGVTRIGGV
                     IPVPLTERDIDLHPDIVLPTHPNGMTFTAAGPHGRVLATETYFSVGGGFIVTEQTSGN
                     SGQHPCSVALPYVSAQELLDICDRLDVSISEAALRNETCCRTENEVRAALLHLRDVMV
                     ECEQRSIAREGLLPGGLRVRRRAKVWYDRLNAEDPTRKPEFAEDWVNLVALAVNEENA
                     SGGRVVTAPTNGAAGIVPAVLHYAIHYTSAGAGDPDDVTVRFLLTAGAIGSLFKERAS
                     ISGAEVGCQGEVGSAAAMAAAGLAEILGGTPRQVENAAEIAMEHSLGLTCDPIAGLVQ
                     IPCIERNAISAGKAINAARMALRGDGIHRVTLDQVIDTMRATGADMHTKYKETSAGGL
                     AINVAVNIVEC"
     gene            complement(77616..78893)
                     /gene="glyA2"
                     /locus_tag="Y980_0070c"
     CDS             complement(77616..78893)
                     /gene="glyA2"
                     /locus_tag="Y980_0070c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00096"
                     /note="Rv0070c, (MTV030.13c) glyA2, serine
                     hydroxymethyltransferase. Contains PS00096 Serine
                     hydroxymethyltransferase pyridoxal-phosphate attachment
                     site. Belongs to the ShmT family. Cofactor: pyridoxal
                     phosphate."
                     /codon_start=1
                     /transl_table=11
                     /product="Serine hydroxymethyltransferase GlyA2 (serine
                     methylase 2) (SHMT 2)"
                     /protein_id="AJF01414.1"
                     /db_xref="GOA:O53615"
                     /db_xref="InterPro:IPR001085"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="InterPro:IPR019798"
                     /db_xref="UniProtKB/Swiss-Prot:O53615"
                     /translation="MNTLNDSLTAFDPDIAALIDGELRRQESGLEMIASENYAPLAVM
                     QAQGSVLTNKYAEGYPGRRYYGGCEFVDGVEQLAIDRVKALFGAEYANVQPHSGATAN
                     AATMHALLNPGDTILGLSLAHGGHLTHGMRINFSGKLYHATAYEVSKEDYLVDMDAVA
                     EAARTHRPKMIIAGWSAYPRQLDFARFRAIADEVDAVLMVDMAHFAGLVAAGVHPSPV
                     PHAHVVTSTTHKTLGGPRGGIILCNDPAIAKKINSAVFPGQQGGPLEHVIAAKATAFK
                     MAAQPEFAQRQQRCLDGARILAGRLTQPDVAERGIAVLTGGTDVHLVLVDLRDAELDG
                     QQAEDRLAAVDITVNRNAVPFDPRPPMITSGLRIGTPALAARGFSHNDFRAVADLIAA
                     ALTATNDDQLGPLRAQVQRLAARYPLYPELHRT"
     gene            79483..80190
                     /locus_tag="Y980_0071"
     CDS             79483..80190
                     /locus_tag="Y980_0071"
                     /note="Rv0071, (MTV030.14) Possible maturase,similar to
                     many proteins of the group II intron maturase family.
                     Contains 5 VDP repeats at N-terminus, these are also found
                     in two Streptococcus plasmid hypothetical proteins
                     Q52246|X17092 and Q54942|X66468."
                     /codon_start=1
                     /transl_table=11
                     /product="putative maturase"
                     /protein_id="AJF01415.1"
                     /db_xref="GOA:L0T2C5"
                     /db_xref="InterPro:IPR000477"
                     /db_xref="UniProtKB/TrEMBL:L0T2C5"
                     /translation="MSSITVSVDPVDPVDPVDPVDPVDAVVAAGSDGLTVARIESEIG
                     ALEFLNELRTELKSGQFRPQPVRERKIPKPGGLGKVRRLGIPTVADRVVQAALKLVLE
                     PIFETDFEPVSYGFRPARRAHDTIAEIHLFGTQEYRWVLDADIKACFDRIDHADLMDR
                     VRHRIKDKRVLRLVNWQRIRHRWNWTDVRRWLTDPTGRWHPISADGITLFNPAAVPIR
                     RYRYRGNTIPTPWTQAV"
     repeat_region   79504..79548
                     /locus_tag="Y980_0071"
                     /note="5 x 9 bp GTGGACCCG repeats"
     repeat_region   80233..80547
                     /note="(MTV030.15), len: 315 nt. Probable REP'-1
                     pseudogene fragment, similar to many Mycobacterium
                     tuberculosis proteins inside REP13E12 elements e.g.
                     Q50655|Z95390|MTCY13E12.20 (317 aa), but no possible start
                     site."
     gene            80621..81670
                     /locus_tag="Y980_0072"
     CDS             80621..81670
                     /locus_tag="Y980_0072"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0072, (MTV030.16) Probable glutamine-transport
                     transmembrane protein ABC-transporter (see citation
                     below). Note that supposed act with near ORF
                     Rv0073|MTV030.17 ATP-binding protein ABC-transporter."
                     /codon_start=1
                     /transl_table=11
                     /product="putative glutamine-transport transmembrane
                     protein ABC transporter"
                     /protein_id="AJF01416.1"
                     /db_xref="GOA:O53617"
                     /db_xref="InterPro:IPR003838"
                     /db_xref="InterPro:IPR025857"
                     /db_xref="UniProtKB/Swiss-Prot:O53617"
                     /translation="MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGLANGFRVEA
                     RHTVDSMGVDVFVVRSGAAGPFLGSIPFPDVDLARVAAEPGVMAAAPLGSVGTIMKEG
                     TSTRNVTVFGAPEHGPGMPRVSEGRSPSKPDEVAASSTMGRHLGDTVEVGARRLRVVG
                     IVPNSTALAKIPNVFLTTEGLQKLAYNGQPNITSIGIIGMPRQLPEGYQTFDRVGAVN
                     DLVRPLKVAVNSISIVAVLLWIVAVLIVGSVVYLSALERLRDFAVFKAIGTPTRSIMA
                     GLALQALVIALLAAVVGVVLAQVLAPLFPMIVAVPVGAYLALPVAAIVIGLFASVAGL
                     KRVVTVDPAQAFGGP"
     gene            81673..82665
                     /locus_tag="Y980_0073"
     CDS             81673..82665
                     /locus_tag="Y980_0073"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00017"
                     /inference="protein motif:PROSITE:PS00211"
                     /inference="protein motif:PROSITE:PS00889"
                     /note="Rv0073, (MTV030.17) Probable glutamine-transport
                     ATP-binding protein ABC-transporter (see citation below),
                     similar to many ATP-binding proteins. Contains PS00017
                     ATP/GTP-binding site motif A (P-loop),PS00211 ABC
                     transporters family signature, and PS00889 Cyclic
                     nucleotide-binding domain signature 2. Belongs to the
                     ATP-binding transport protein family (ABC transporters).
                     Note that supposed act with near ORF Rv0072|MTV030.16
                     transmembrane ABC-transporter."
                     /codon_start=1
                     /transl_table=11
                     /product="putative glutamine-transport ATP-binding protein
                     ABC transporter"
                     /protein_id="AJF01417.1"
                     /db_xref="GOA:O53618"
                     /db_xref="InterPro:IPR000595"
                     /db_xref="InterPro:IPR002373"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR018488"
                     /db_xref="InterPro:IPR018490"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/Swiss-Prot:O53618"
                     /translation="MGDLSIQNLVVEYYSGGYALRPINGLNLDVAAGSLVMLLGPSGC
                     GKTTLLSCLGGILRPKSGAIKFDEVDITTLQGAELANYRRNKVGIVFQAFNLVPSLTA
                     VENVMVPLRSAGMSRRASRRRAEELLARVNLAERMNHRPGDLSGGQQQRVAVARAIAL
                     DPPLILADEPTAHLDFIQVEEVLRLIRELADGERVVVVATHDSRMLPMADRVVELTPD
                     FAETNRPPETVHLQAGEVLFEQSTMGDLIYVVSEGEFEIVHELADGGEELVKVAGPGD
                     YFGEIGVLFHLPRSATVRARSDATAVGYTVQAFRERLGVGGLRDLIEHRALAND"
     gene            82745..83980
                     /locus_tag="Y980_0074"
     CDS             82745..83980
                     /locus_tag="Y980_0074"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0074, (MTV030.18) Conserved protein,similar to
                     many."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01418.1"
                     /db_xref="GOA:L7N543"
                     /db_xref="InterPro:IPR006680"
                     /db_xref="InterPro:IPR011059"
                     /db_xref="UniProtKB/TrEMBL:L7N543"
                     /translation="MGDLSISQVSARPGRIGIRARQMFDGYRFQRGPVLVVVEDGRIS
                     AVDFAGSACPDMNLVDLGESTLLPGLVDAHAHLCWDPDGRPEDLAGDPHAVLVGRARR
                     HAAAALRSGITTIRDLGDRDYAALALREEYRQKTTVGPELVVSGPPLTRSGGHCWFLG
                     GVADSVEELVDAVQERAARGADWIKVMATGGFVTTASDPWQPQYGSGQLAAVVAAAEQ
                     VGLPVTAHAHATAGIAAAVAAGVDGIEHCTFLSEGSAAASPDVVEAIVAQGVWCGMTI
                     PRVYPEMPENLVAVVQDGWRNIRRLIDAGARVALSTDAGVAPGRRHDVLPDDLVYLSR
                     HGFTSTEVLTGATAAAAASCGLGHRKGRIAPGYDADLLAVAAGVDHDPAGLCDVKAVW
                     RSGTQVPLQASAVGYNTPS"
     gene            83993..85165
                     /locus_tag="Y980_0075"
     CDS             83993..85165
                     /locus_tag="Y980_0075"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0075, (MTV030.19) Probable aminotransferase,
                     similar to many class-II pyridoxal-phosphate-dependent
                     aminotransferases (MALY/PATB subfamily). Also similar to
                     other proteins from Mycobacterium tuberculosis e.g.
                     Rv2294, Rv0858c, etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminotransferase"
                     /protein_id="AJF01419.1"
                     /db_xref="GOA:L7N5E9"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/TrEMBL:L7N5E9"
                     /translation="MQDSIFNLLTEEQLRGRNTLKWNYFGPDVVPLWLAEMDFPTAPA
                     VLDGVRACVDNEEFGYPPLGEDSLPRATADWCRQRYGWCPRPDWVRVVPDVLKGMEVV
                     VEFLTRPESPVALPVPAYMPFFDVLHVTGRQRVEVPMVQQDSGRYLLDLDALQAAFVR
                     GAGSVIICNPNNPLGTAFTEAELRAIVDIAARHGARVIADEIWAPVVYGSRHVAAASV
                     SEAAAEVVVTLVSASKGWNLPGLMCAQVILSNRRDAHDWDRINMLHRMGASTVGIRAN
                     IAAYHHGESWLDELLPYLRANRDHLARALPELAPGVEVNAPDGTYLSWVDFRALALPS
                     EPAEYLLSKAKVALSPGIPFGAAVGSGFARLNFATTRAILDRAIEAIAAALRDIID"
     gene            complement(85180..85569)
                     /locus_tag="Y980_0076c"
     CDS             complement(85180..85569)
                     /locus_tag="Y980_0076c"
                     /note="Rv0076c, (MTV030.20c) Probable membrane protein,
                     with membrane-spanning domain at C-terminus."
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane protein"
                     /protein_id="AJF01420.1"
                     /db_xref="UniProtKB/TrEMBL:L7N5K7"
                     /translation="MPAVTTPSNHWGDERRKLSHQPPVRGQILGRRQARRLSQHFARV
                     GVEAPPKRLQEMLLGAPAADEEWTDVKFALIVTQLNHEKRVAKFHRLQRRATHSLICL
                     GLVLVALNFLICLAYIFFSLTQHAAAL"
     gene            complement(85633..86463)
                     /locus_tag="Y980_0077c"
     CDS             complement(85633..86463)
                     /locus_tag="Y980_0077c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0077c, (MTV030.21c) Possible oxidoreductase,
                     weakly similar to others from Streptomyces. Also similar
                     to MTCY05A6_35 and MTCY1A11_10 from Mycobacterium
                     tuberculosis. And shows some similarity in part with
                     AAL17935.1|AY054120 putative epoxide hydrolase from
                     Mycobacterium smegmatis (203 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01421.1"
                     /db_xref="InterPro:IPR000073"
                     /db_xref="UniProtKB/TrEMBL:L0T2I5"
                     /translation="MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERL
                     AGRGLRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGNDTGGV
                     VTQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSATLFRAAIQVMRAPAAR
                     NRAYAGLSHHNIDHLTRAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAARLPEFDKP
                     ALIAWSADDVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT
                     "
     gene            86525..87130
                     /locus_tag="Y980_0078"
     CDS             86525..87130
                     /locus_tag="Y980_0078"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0078, (MTV030.22) Probable transcriptional
                     regulator. Contains probable helix-turn-helix motif from
                     aa 35 to 56 (Score 1348, +3.78 SD)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein"
                     /protein_id="AJF01422.1"
                     /db_xref="GOA:L7N4U6"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:L7N4U6"
                     /translation="MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEA
                     GVTRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLE
                     VSGDPEVRQLILLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLA
                     QVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG"
     gene            complement(87205..87798)
                     /locus_tag="Y980_0078A"
     CDS             complement(87205..87798)
                     /locus_tag="Y980_0078A"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0078A Hypothetical unknown protein. This region
                     is a possible MT-complex-specific genomic island (See Becq
                     et al., 2007)."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /protein_id="AJF01423.1"
                     /db_xref="InterPro:IPR014942"
                     /db_xref="UniProtKB/TrEMBL:Q8VKS0"
                     /translation="MNAVESTLRRVAKDLTGLRQRWALVGGFAVSARSEPRFTRDVDI
                     VVAVANDDAAESLVRQLLTQQYHLLASVEQDAARRLAAVRLGATADTAANVVVDLLFA
                     SCGIEPEIAEAAEEIEILPDLVAPVATTAHLIAMKLLARDDDRRPQDRSDLRALVDAA
                     SPQDIQDARKAIELITLRGFHRDRDLAAEWTRLAAKW"
     gene            complement(87795..88001)
                     /locus_tag="Y980_0078B"
     CDS             complement(87795..88001)
                     /locus_tag="Y980_0078B"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0078B Conserved protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01424.1"
                     /db_xref="UniProtKB/TrEMBL:L0T493"
                     /translation="MAVSVAAQKLRLALDMYEVGEQMQRMRLGRERPNADVVEIEAAI
                     DAWRMTRPGAEEGDSAGPTSTRFT"
     gene            88201..89022
                     /locus_tag="Y980_0079"
     CDS             88201..89022
                     /locus_tag="Y980_0079"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0079, (MTV030.23) Unknown protein. Predicted
                     possible vaccine candidate (See Zvi et al.,2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01425.1"
                     /db_xref="GOA:O53624"
                     /db_xref="UniProtKB/Swiss-Prot:O53624"
                     /translation="MEPKRSRLVVCAPEPSHAREFPDVAVFSGGRANASQAERLARAV
                     GRVLADRGVTGGARVRLTMANCADGPTLVQINLQVGDTPLRAQAATAGIDDLRPALIR
                     LDRQIVRASAQWCPRPWPDRPRRRLTTPAEALVTRRKPVVLRRATPLQAIAAMDAMDY
                     DVHLFTDAETGEDAVVYRAGPSGLRLARQHHVFPPGWSRCRAPAGPPVPLIVNSRPTP
                     VLTEAAAVDRAREHGLPFLFFTDQATGRGQLLYSRYDGNLGLITPTGDGVADGLA"
     gene            89019..89477
                     /locus_tag="Y980_0080"
     CDS             89019..89477
                     /locus_tag="Y980_0080"
                     /note="Rv0080, (MTV030.24) Conserved hypothetical protein.
                     Belongs to pyridoxine 5'-phosphate (PNP) oxidase-like
                     (PNPOx-like) superfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01426.1"
                     /db_xref="GOA:O53625"
                     /db_xref="InterPro:IPR012349"
                     /db_xref="InterPro:IPR024747"
                     /db_xref="UniProtKB/Swiss-Prot:O53625"
                     /translation="MSPGSRRASPQSAREVVELDRDEAMRLLASVDHGRVVFTRAALP
                     AIRPVNHLVVDGRVIGRTRLTAKVSVAVRSSADAGVVVAYEADDLDPRRRTGWSVVVT
                     GLATEVSDPEQVARYQRLLHPWVNMAMDTVVAIEPEIVTGIRIVADSRTP"
     gene            89572..89916
                     /locus_tag="Y980_0081"
     CDS             89572..89916
                     /locus_tag="Y980_0081"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0081, (MTV030.25) Probable transcriptional
                     regulator, highly similar to others."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein"
                     /protein_id="AJF01427.1"
                     /db_xref="GOA:O53626"
                     /db_xref="InterPro:IPR001845"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/Swiss-Prot:O53626"
                     /translation="MESEPLYKLKAEFFKTLAHPARIRILELLVERDRSVGELLSSDV
                     GLESSNLSQQLGVLRRAGVVAARRDGNAMIYSIAAPDIAELLAVARKVLARVLSDRVA
                     VLEDLRAGGSAT"
     gene            89921..90400
                     /locus_tag="Y980_0082"
     CDS             89921..90400
                     /locus_tag="Y980_0082"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0082, (MTV030.26) Probable oxidoreductase, highly
                     similar or similar to other various oxidoreductases.
                     Nucleotide position 90144 in the genome sequence has been
                     corrected, A:G resulting in Q74R."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01428.1"
                     /db_xref="GOA:Q7DAH3"
                     /db_xref="InterPro:IPR006137"
                     /db_xref="InterPro:IPR014406"
                     /db_xref="UniProtKB/TrEMBL:Q7DAH3"
                     /translation="MGWVAKIFRVGRVVEPAAPLPAAIAEPPAGVRGSLQIRHVDAGS
                     CNGCEVEISGAFGPVYDAERFGARLVASPRHADALLVTGVVTHNMAGPLRKTLEATPR
                     PRVVIACGDCALNRGVFADAYGVVGAVGEVVPVDVEIAGCPPTPAAIMAALRSVTGK"
     gene            90397..92319
                     /locus_tag="Y980_0083"
     CDS             90397..92319
                     /locus_tag="Y980_0083"
                     /note="Rv0083, (MTV030.27, MTCY251.01) Probable
                     oxidoreductase, showing some similarity to other various
                     oxidoreductases. Nucleotide position 91071 in the genome
                     sequence has been corrected, T:C resulting in I224I."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01429.1"
                     /db_xref="GOA:Q10880"
                     /db_xref="InterPro:IPR001750"
                     /db_xref="InterPro:IPR003918"
                     /db_xref="UniProtKB/Swiss-Prot:Q10880"
                     /translation="MTAAPTAGGVVTSGVGVAGVGVGLLGMFGPVRVVHVGWLLPLSG
                     VHIELDRLGGFFMALTGAVAAPVGCYLIGYVRREHLGRVPMAVVPLFVAAMLLVPAAG
                     SVTTFLLAWELMAIASLILVLSEHARPQVRSAGLWYAVMTQLGFIAILVGLVVLAAAG
                     GSDRFAGLGAVCDGVRAAVFMLTLVGFGSKAGLVPLHAWLPRAHPEAPSPVSALMSAA
                     MVNLGIYGIVRFDLQLLGPGPRWWGLALLAVGGTSALYGVLQASVAADLKRLLAYSTT
                     ENMGLITLALGAATLFADTGAYGPASIAAAAAMLHMIAHAAFKSLAFMAAGSVLAATG
                     LRDLDLLGGLARRMPATTVFFGVAALGACGLPLGAGFVSEWLLVQSLIHAAPGHDPIV
                     ALTTPLAVGVVALATGLSVAAMTKAFGIGFLARPRSTQAEAAREAPASMRAGMAIAAG
                     ACLVLAVAPLLVAPMVRRAAATLPAAQAVKFTGLGAVVRLPAMSGSIAPGVIAAAVLA
                     AALAVAVLARWRFRRRPAPARLPLWACGAADLTVRMQYTATSFAEPLQRVFGDVLRPD
                     TDIEVTHTAESRYMAERITYRTAVADAIEQRLYTPVVGAVAAMAELLRRAHTGSVHRY
                     LAYGALGVLIVLVVAR"
     gene            92325..93275
                     /gene="hycD"
                     /locus_tag="Y980_0084"
                     /gene_synonym="hevD"
     CDS             92325..93275
                     /gene="hycD"
                     /locus_tag="Y980_0084"
                     /gene_synonym="hevD"
                     /note="Rv0084, (MTCY251.02) Possible hycD (alternate gene
                     name: hevD), formate hydrogenlyase,integral membrane
                     protein, similar to others. Belongs to the complex I
                     subunit 1 family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative formate hydrogenlyase HycD (FHL)"
                     /protein_id="AJF01430.1"
                     /db_xref="GOA:L7N4H6"
                     /db_xref="InterPro:IPR001694"
                     /db_xref="UniProtKB/TrEMBL:L7N4H6"
                     /translation="MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWR
                     DLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVG
                     LLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGAL
                     VASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAG
                     PRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLL
                     ATFEVFLAKLRLFRVPELLAGSFLLALLAVTAANFFTVGA"
     gene            93286..93948
                     /gene="hycP"
                     /locus_tag="Y980_0085"
     CDS             93286..93948
                     /gene="hycP"
                     /locus_tag="Y980_0085"
                     /note="Rv0085, (MTCY251.03) Possible hycP,hydrogenase,
                     integral membrane protein. Belongs to
                     NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
                     superfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="putative hydrogenase HycP"
                     /protein_id="AJF01431.1"
                     /db_xref="GOA:P64681"
                     /db_xref="UniProtKB/Swiss-Prot:P64681"
                     /translation="MSNANFSILVDFAAGGLVLASVLIVWRRDLRAIVRLLAWQGAAL
                     AAIPLLRGIRDNDRALIAVGIAVLALRALVLPWLLARAVGAEAAAQREATPLVNTASS
                     LLITAGLTLTAFAITQPVVNLEPGVTINAVPAAFAVVLIALFVMTTRLHAVSQAAGFL
                     MLDNGIAATAFLLTAGVPLIVELGASLDVLFAVIVIGVLTGRLRRIFGDADLDKLREL
                     RD"
     gene            93948..95414
                     /gene="hycQ"
                     /locus_tag="Y980_0086"
     CDS             93948..95414
                     /gene="hycQ"
                     /locus_tag="Y980_0086"
                     /note="Rv0086, (MTCY251.04) Possible hycQ,hydrogenase,
                     integral membrane protein. Belongs to the
                     NADH-Ubiquinone/plastoquinone (complex I) superfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="putative hydrogenase HycQ"
                     /protein_id="AJF01432.1"
                     /db_xref="GOA:L7N4G0"
                     /db_xref="InterPro:IPR001750"
                     /db_xref="UniProtKB/TrEMBL:L7N4G0"
                     /translation="MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAV
                     AMGFWMGSGAQFGLGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGR
                     SARLYGVLTPAFLCAMVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKY
                     VVICSVGIAVAFLGTVLLYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLL
                     IGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAY
                     LRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLL
                     HVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPF
                     AMFASELAIARSLANERLAWVLGAALLLIAIGFTALARNSGRMLLGTPAAGAPAITVP
                     ATAAAALMVGIVVSAALGITAGPLADLLGIAASNVGLP"
     gene            95411..96889
                     /gene="hycE"
                     /locus_tag="Y980_0087"
                     /gene_synonym="hevE"
     CDS             95411..96889
                     /gene="hycE"
                     /locus_tag="Y980_0087"
                     /gene_synonym="hevE"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0087, (MTCY251.05) Possible hycE (alternate gene
                     name: hevE), formate hydrogenlyase, similar to others.
                     Belongs to the complex I 49 kDa subunit family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative formate hydrogenase HycE (FHL)"
                     /protein_id="AJF01433.1"
                     /db_xref="GOA:L0T5H4"
                     /db_xref="InterPro:IPR001135"
                     /db_xref="InterPro:IPR001268"
                     /db_xref="InterPro:IPR001501"
                     /db_xref="InterPro:IPR020396"
                     /db_xref="UniProtKB/TrEMBL:L0T5H4"
                     /translation="MMSASWLRHRVSERGLIATAEQLWADSFRLALVAAHDDGDSLRV
                     VYLFLAGYPDRRVELEYVVPADNPEIRSLAYLSFPAGRFEREMADLYGIRPVGHPKPR
                     RLVRHAHWPDWHPMRTDAGPAPEFTDTGAFPFLAVEGPGVYEIPVGPVHAGLIEPGHF
                     RFSVAGETIVRLKARLWFVHRGIEKLFHGRPATAAVDLAERISGDTSAAHALAHSLAI
                     EDALGIELPHEVHRLRALIVELERLYNHAADLGALANDVGYSLANAHAQRIRENLLRR
                     NAAVTGHRLLRGAIRAGGVALRALPDTDELAALAVDLAEVATLTLANSVVYDRFAGTA
                     VLHPDDASALGCLGYVARASGLRSDARVEHPTIVLPITEIGAPDGDVLARYTVRRDEF
                     AASAALAQHIVESHTGPIEYAATLHPVGAPSSGIGIVEGWRGTIVHRVEIDVDGRITR
                     AKVVDPSWFNWPALPVAMADTIVPDFPLANKSFNQSYAGNDL"
     gene            96924..97598
                     /locus_tag="Y980_0088"
     CDS             96924..97598
                     /locus_tag="Y980_0088"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0088, (MTCY251.06) Possible polyketide
                     cyclase/dehydrase. Belongs to the SRPBCC ligand-binding
                     domain superfamily. Predicted to be an outer membrane
                     protein (See Song et al., 2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative polyketide cyclase/dehydrase"
                     /protein_id="AJF01434.1"
                     /db_xref="GOA:P0A5C3"
                     /db_xref="InterPro:IPR019587"
                     /db_xref="InterPro:IPR023393"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5C3"
                     /translation="MSVYKHAPSRVRLRQTRSTVVKGRSGSLSWRRVRTGDLGLAVWG
                     GREEYRAVKPGTPGIQPKGDMMTVTVVDAGPGRVSRSVEVAAPAAELFAIVADPRRHR
                     ELDGSGTVRGNIKVPAKLVVGSKFSTKMKLFGLPYRITSRVTALKPNELVEWSHPLGH
                     RWRWEFESLSPTLTRVTETFDYHAAGAIKNGLKFYEMTGFAKSNAAGIEATLAKLSDQ
                     YARGRA"
     gene            97755..98348
                     /locus_tag="Y980_0089"
     CDS             97755..98348
                     /locus_tag="Y980_0089"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0089, (MTCY251.07) Possible methyltransferase,
                     showing some weak similarity to others. Also some
                     similarity with many biotin biosynthesis proteins. Belongs
                     to the methyltransferase superfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="putative methyltransferase/methylase"
                     /protein_id="AJF01435.1"
                     /db_xref="GOA:P65346"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="UniProtKB/Swiss-Prot:P65346"
                     /translation="MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRI
                     PYVTAVDIDAPVLRRAQTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTR
                     TALSRLGGLVTPGGTLAVVTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWP
                     PPQTLHELRSHVRALLPGACIRRLLYGRVLVTWRAPV"
     gene            98477..99247
                     /locus_tag="Y980_0090"
     CDS             98477..99247
                     /locus_tag="Y980_0090"
                     /note="Rv0090, (MTCY251.08) Possible membrane protein.
                     Contains IPR014511 Protein of unknown function DUF2068,
                     transmembrane, subgroup."
                     /codon_start=1
                     /transl_table=11
                     /product="putative membrane protein"
                     /protein_id="AJF01436.1"
                     /db_xref="GOA:P64683"
                     /db_xref="InterPro:IPR014511"
                     /db_xref="InterPro:IPR021125"
                     /db_xref="UniProtKB/Swiss-Prot:P64683"
                     /translation="MAKNQNRIRNRWELITCGLGGHVTYAPDDAALAARLRASTGLGE
                     VWRCLRCGDFALGGPQGRGAPEDAPLIMRGKALRQAIIIRALGVERLVRALVLALAAW
                     AVWEFRGARGAIQATLDRDLPVLRAAGFKVDQMTVIHALEKALAAKPSTLALITGMLA
                     AYAVLQAVEGVGLWLLKRWGEYFAVVATSIFLPLEVHDLAKGITTTRVVTFSINVAAV
                     VYLLISKRLFGVRGGRKAYDVERRGEQLLDLERAAMLT"
     gene            99681..100448
                     /gene="mtn"
                     /locus_tag="Y980_0091"
                     /gene_synonym="pfs"
     CDS             99681..100448
                     /gene="mtn"
                     /locus_tag="Y980_0091"
                     /gene_synonym="pfs"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0091, (MTCY251.10) Probable mtn (alternate gene
                     name: pfs),methylthioadenosine/S-Adenosylhomocysteine
                     nucleosidase (MTA/SAH nucleosidase), including
                     5'-methylthioadenosine nucleosidase and
                     S-adenosylhomocysteine nucleosidase,similar to others.
                     Belongs to the MTN family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional MTA/SAH nucleosidase Mtn:
                     5'-methylthioadenosine nucleosidase (methylthioadenosine
                     methylthioribohydrolase) + S-adenosylhomocysteine
                     nucleosidase (S-adenosyl-L-homocysteine
                     homocysteinylribohydrolase)"
                     /protein_id="AJF01437.1"
                     /db_xref="GOA:P67656"
                     /db_xref="InterPro:IPR000845"
                     /db_xref="InterPro:IPR010049"
                     /db_xref="InterPro:IPR018017"
                     /db_xref="UniProtKB/Swiss-Prot:P67656"
                     /translation="MAVTVGVICAIPQELAYLRGVLVDAKRQQVAQILFDSGQLDAHR
                     VVLAAAGMGKVNTGLTATLLADRFGCRTIVFTGVAGGLDPELCIGDIVIADRVVQHDF
                     GLLTDERLRPYQPGHIPFIEPTERLGYPVDPAVIDRVKHRLDGFTLAPLSTAAGGGGR
                     QPRIYYGTILTGDQYLHCERTRNRLHHELGGMAVEMEGGAVAQICASFDIPWLVIRAL
                     SDLAGADSGVDFNRFVGEVAASSARVLLRLLPVLTAC"
     gene            100580..102865
                     /gene="ctpA"
                     /locus_tag="Y980_0092"
     CDS             100580..102865
                     /gene="ctpA"
                     /locus_tag="Y980_0092"
                     /inference="protein motif:PROSITE:PS00154"
                     /inference="protein motif:PROSITE:PS01047"
                     /note="Rv0092, (MTCY251.11) CtpA,cation-transporting
                     P-type ATPase a (transmembrane protein), highly similar to
                     many. Contains PS01047 Heavy-metal-associated domain, and
                     PS00154 E1-E2 ATPases phosphorylation site. Belongs to the
                     cation transport ATPases family (E1-E2 ATPases), subfamily
                     IB."
                     /codon_start=1
                     /transl_table=11
                     /product="Cation transporter P-type ATPase a CtpA"
                     /protein_id="AJF01438.1"
                     /db_xref="GOA:Q10876"
                     /db_xref="InterPro:IPR000579"
                     /db_xref="InterPro:IPR001757"
                     /db_xref="InterPro:IPR006121"
                     /db_xref="InterPro:IPR008250"
                     /db_xref="InterPro:IPR017969"
                     /db_xref="InterPro:IPR018303"
                     /db_xref="InterPro:IPR023214"
                     /db_xref="InterPro:IPR023299"
                     /db_xref="InterPro:IPR027256"
                     /db_xref="UniProtKB/Swiss-Prot:Q10876"
                     /translation="MTTAVTGEHHASVQRIQLRISGMSCSACAHRVESTLNKLPGVRA
                     AVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDPDADHARQLLIRL
                     AIAAVLFVPVADLSVMFGVVPATRFTGWQWVLSALALPVVTWAAWPFHRVAMRNARHH
                     AASMETLISVGITAATIWSLYTVFGNHSPIERSGIWQALLGSDAIYFEVAAGVTVFVL
                     VGRYFEARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPGQI
                     VAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVEAAAVGADTQF
                     AGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTAAGWLIAGGQPDRAVSAAL
                     AVLVIACPCALGLATPTAMMVASGRGAQLGIFLKGYKSLEATRAVDTVVFDKTGTLTT
                     GRLQVSAVTAAPGWEADQVLALAATVEAASEHSVALAIAAATTRRDAVTDFRAIPGRG
                     VSGTVSGRAVRVGKPSWIGSSSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIAVAD
                     AVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGIDEVIADILPEGKVDVIEQ
                     LRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVAIGAADIILVRDHLDVVPLALD
                     LARATMRTVKLNMVWAFGYNIAAIPVAAAGLLNPLVAGAAMAFSSFFVVSNSLRLRKF
                     GRYPLGCGTVGGPQMTAPSSA"
     gene            complement(102812..103660)
                     /locus_tag="Y980_0093c"
     CDS             complement(102812..103660)
                     /locus_tag="Y980_0093c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0093c, (MTCY251.12c) Probable conserved membrane
                     protein, equivalent only to CAC30943.1|AL583924 probable
                     integral membrane protein from Mycobacterium leprae (237
                     aa). A core mycobacterial gene; conserved in mycobacterial
                     strains (See Marmiesse et al.,2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved membrane protein"
                     /protein_id="AJF01439.1"
                     /db_xref="GOA:Q10890"
                     /db_xref="InterPro:IPR027383"
                     /db_xref="UniProtKB/Swiss-Prot:Q10890"
                     /translation="MLAQATTAGSFNHHASTVLQGCRGVPAAMWSEPAGAIRRHCATI
                     DGMDCEVAREALSARLDGERAPVPSARVDEHLGECSACRAWFTQVASQAGDLRRLAES
                     RPVVPPVGRLGIRRAPRRQHSPMTWRRWALLCVGIAQIALGTVQGFGLDVGLTHQHPT
                     GAGTHLLNESTSWSIALGVIMVGAALWPSAAAGLAGVLTAFVAILTGYVIVDALSGAV
                     STTRILTHLPVVIGAVLAIMVWRSASGPRPRPDAVAAEPDIVLPDNASRGRRRGHLWP
                     TDGSAA"
     gene            complement(103707..104660)
                     /locus_tag="Y980_0094c"
     CDS             complement(103707..104660)
                     /locus_tag="Y980_0094c"
                     /note="Rv0094c, (MTCY251.13c) Member of 13E12 repeat
                     family, showing some similarity to U15187|MLU15187_7 from
                     Mycobacterium leprae (94 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01440.1"
                     /db_xref="InterPro:IPR003615"
                     /db_xref="InterPro:IPR003870"
                     /db_xref="UniProtKB/TrEMBL:L0T2F6"
                     /translation="MSTRQAAEADLAGKAAQYRPDELARYAQRVMDWLHPDGDLTDTE
                     RARKRGITLSNQQYDGMSRLSGYLTPQARATFEAVLAKLAAPGATNPDDHTPVIDTTP
                     DAAAIDRDTRSQAQRNHDGLLAGLRALIASGKLGQHNGLPVSIVVTTTLTDLQTGAGK
                     GFTGGGTLLPMADVIRMTSHAHHYSPASGRYPQAIFDHGTPLALYHTKRLASPAQRIM
                     LFANDRGCTKPGCDAPAYHSQAHHVTAWTSTGRTDITELTLACGPDNRLAEKGWTTHN
                     NTHGHTEWLPPPHLDHGQPRTNTFHHPERFLHNQDDDDKPD"
     repeat_region   complement(103710..105212)
                     /note="REP-2, len: 1503 nt. REP251, member of REP13E12
                     family."
     gene            complement(104802..105212)
                     /locus_tag="Y980_0095c"
     CDS             complement(104802..105212)
                     /locus_tag="Y980_0095c"
                     /note="Rv0095c, (MTCY251.14c) Member of 13E12 repeat, also
                     partially similar to AF0418|AF041819_8 from Mycobacterium
                     bovis BCG (222 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01441.1"
                     /db_xref="InterPro:IPR003870"
                     /db_xref="UniProtKB/Swiss-Prot:Q10891"
                     /translation="MRYLPVSTRRIWVNPLCHFSFTVISGALFVSARRYDSNMLANSR
                     EELVEVFDALDADLDRLDEVSFEVLSTPERLRSLERLECLARRLPAAQHTLINQLDTQ
                     ASEEELGGTLCCALANRLRITKPEAGRRSAEAKP"
     gene            105321..106712
                     /gene="PPE1"
                     /locus_tag="Y980_0096"
     CDS             105321..106712
                     /gene="PPE1"
                     /locus_tag="Y980_0096"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0096, (MTCY251.15) PPE1, Member of the
                     Mycobacterium tuberculosis PPE family, similar to many. A
                     core mycobacterial gene; conserved in mycobacterial
                     strains (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="PPE family protein PPE1"
                     /protein_id="AJF01442.1"
                     /db_xref="GOA:Q10892"
                     /db_xref="InterPro:IPR000030"
                     /db_xref="UniProtKB/Swiss-Prot:Q10892"
                     /translation="MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQ
                     LLGEVQASSWQGTAATQYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMP
                     TPAELAANHAIHGVLIATNFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATV
                     AVPSTQPAPPIRAPGGDAADTRLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSP
                     AVTVVLALVALQLYDFLWYPYYASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLL
                     PIAAALGPGDQWGANLAVAVTPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISY
                     AVPGLAPPGVSSGPKAGTKSPDTAADTLATAGAARPGLARAHRRKRSESGVGIRGYRD
                     EFLDATATVDAATDVPAPANAAGSQGAGTLGFAGTAPTTSGAAAGMVQLSSHSTSTTV
                     PLLPTTWTTDAEQ"
     gene            106731..107600
                     /locus_tag="Y980_0097"
     CDS             106731..107600
                     /locus_tag="Y980_0097"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00077"
                     /note="Rv0097, (MTCY251.16) Possible oxidoreductase,
                     equivalent to NP_302343.1|NC_002677 putative
                     oxidoreductase from Mycobacterium leprae (289 aa). Also
                     highly similar to BAB69377.1|AB070955 putative
                     oxidoreductase from Streptomyces avermitilis (296 aa).
                     Contains PS00077 Cytochrome c oxidase subunit I, copper B
                     binding region signature."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01443.1"
                     /db_xref="GOA:P67755"
                     /db_xref="InterPro:IPR003819"
                     /db_xref="UniProtKB/Swiss-Prot:P67755"
                     /translation="MTLKVKGEGLGAQVTGVDPKNLDDITTDEIRDIVYTNKLVVLKD
                     VHPSPREFIKLGRIIGQIVPYYEPMYHHEDHPEIFVSSTEEGQGVPKTGAFWHIDYMF
                     MPEPFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAKRDPARGTVSTHDPRRHIKIR
                     PSDVYRPIGEVWDEINRTTPPIKWPTVIRHPKTGQEILYICATGTTKIEDKDGNPVDP
                     EVLQELMAATGQLDPEYQSPFIHTQHYQVGDIILWDNRVLMHRAKHGSAAGTLTTYRL
                     TMLDGLKTPGYAA"
     gene            107597..108148
                     /gene="fcoT"
                     /locus_tag="Y980_0098"
     CDS             107597..108148
                     /gene="fcoT"
                     /locus_tag="Y980_0098"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0098, (MTCY251.17) FcoT, long-chain fatty acyl
                     CoA thioesterase type III (See Wang et al.,2007),
                     equivalent to CAC30948.1|AL583924 from Mycobacterium
                     leprae (183 aa). A core mycobacterial gene; conserved in
                     mycobacterial strains (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fatty acyl CoA thioesterase type III
                     FcoT"
                     /protein_id="AJF01444.1"
                     /db_xref="GOA:P64685"
                     /db_xref="InterPro:IPR022598"
                     /db_xref="PDB:2PFC"
                     /db_xref="PDB:3B18"
                     /db_xref="UniProtKB/Swiss-Prot:P64685"
                     /translation="MSHTDLTPCTRVLASSGTVPIAEELLARVLEPYSCKGCRYLIDA
                     QYSATEDSVLAYGNFTIGESAYIRSTGHFNAVELILCFNQLAYSAFAPAVLNEEIRVL
                     RGWSIDDYCQHQLSSMLIRKASSRFRKPLNPQKFSARLLCRDLQVIERTWRYLKVPCV
                     IEFWDENGGAASGEIELAALNIP"
     gene            108153..109775
                     /gene="fadD10"
                     /locus_tag="Y980_0099"
     CDS             108153..109775
                     /gene="fadD10"
                     /locus_tag="Y980_0099"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00455"
                     /note="Rv0099, (MTCY251.18) Possible fadD10,fatty-acid-CoA
                     synthetase, similar to many. Contains PS00455 putative
                     AMP-binding domain signature. Contains IPR000873
                     AMP-dependent synthetase/ligase domain. Belongs to the
                     ATP-dependent AMP-binding enzyme family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fatty-acid-CoA ligase FadD10
                     (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)"
                     /protein_id="AJF01445.1"
                     /db_xref="GOA:Q10878"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="UniProtKB/Swiss-Prot:Q10878"
                     /translation="MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRY
                     RELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPI
                     AAIERFCQITDPAAALVAPGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASL
                     AGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTY
                     SPLPATHIGGLWWILTCLMHGGLCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVS
                     ELKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTAQVYGLSETGCTALCLPTDDG
                     SIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNP
                     ERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGV
                     REAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESEPMARPSTIVI
                     VTDIPRTQSGKVMRASLAAAATADKARVVVRG"
     gene            109780..110016
                     /locus_tag="Y980_0100"
     CDS             109780..110016
                     /locus_tag="Y980_0100"
                     /note="Rv0100, (MTCY251.19) Conserved hypothetical
                     protein, equivalent only to CAC30950.1|AL583924 conserved
                     hypothetical protein from Mycobacterium leprae (78 aa). A
                     core mycobacterial gene; conserved in mycobacterial
                     strains (See Marmiesse et al.,2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01446.1"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="UniProtKB/Swiss-Prot:P64687"
                     /translation="MRDRILAAVCDVLYIDEADLIDGDETDLRDLGLDSVRFVLLMKQ
                     LGVNRQSELPSRLAANPSIAGWLRELEAVCTEFG"
     gene            109998..117536
                     /gene="nrp"
                     /locus_tag="Y980_0101"
     CDS             109998..117536
                     /gene="nrp"
                     /locus_tag="Y980_0101"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00012"
                     /inference="protein motif:PROSITE:PS00017"
                     /inference="protein motif:PROSITE:PS00455"
                     /note="Rv0101, (MTCY251.20) Probable nrp,peptide
                     synthetase, similar to others e.g.
                     AAD44234.1|AF143772_40|PstB peptide synthetase from
                     Mycobacterium avium (2552 aa); 7476034|S77657 cyclic
                     peptide synthetase from Mycobacterium leprae (1401 aa);
                     part of CAB55600.1|AJ238027 peptide synthetase from
                     Mycobacterium smegmatis (5990). Also similar to e.g.
                     AAD56240.1|AF184977_1|AF184977 DhbF protein from Bacillus
                     subtilis (2378 aa); SRF1_BACSU|P27206 surfactin synthetase
                     subunit 1 (3587 aa): etc. Contains PS00017 ATP/GTP-binding
                     site motif A (P-loop), 2 x PS00455 Putative AMP-binding
                     domain signature, and PS00012 Phosphopantetheine
                     attachment site. Belongs to the ATP-dependent AMP-binding
                     enzyme family. Thought to be not involved in mycobactin
                     biosynthesis (see citation below)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative peptide synthetase Nrp (peptide
                     synthase)"
                     /protein_id="AJF01447.1"
                     /db_xref="GOA:Q10896"
                     /db_xref="HSSP:O30409"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR010080"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="PDB:4DQV"
                     /db_xref="UniProtKB/TrEMBL:Q10896"
                     /translation="MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLA
                     ALHATVLDNPVQLCVLENSGADYPDLVPRLRFGDIVRVGSADEHLQSTWCSGILGKPL
                     VRHTVHTDPNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAGETPSVGAGLAK
                     LREAHRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSVSDAPGTAAKGVLHESATI
                     CGNAFDAILTLSEAQRVPLNVLVAAAAVAVDASLRQNTETLLVHTVDNRFGDSDLNVA
                     TCLVNSVAQTVRFPPFASVSDVVRTLDRGYVKAVRRRWLREEHYRRMYLAINRTSHVE
                     ALTLNFIREPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQRTLNLAIWNRADLP
                     ACKTHPKVAERIAAALESMAAMWDRPIAMIVNDWFGIGPDGTRCQGDWPARQPSTPAW
                     FLDSARGVHQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGC
                     GYSVCDTADEISVRTNAITEHGDGILVTVVDVAATQLAVVGHDELRKVVDERVTQVTH
                     DALLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAISRAYGWGAHDTVLQCAPLTS
                     DISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLPTAVWQLLCADGD
                     AIDAIGRSRLRQIVIGGEAIRCSAVDKWLESAASQGISLLSSYGPTEATVVATFLPIV
                     CDQTTMDGALLRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFGTVTAADGSR
                     RRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVELH
                     SGSLGVWFKSQRTREGEQDAAAATRIRLVLVSLGVSSFFVVGVPNIPRKPNGKIDSDN
                     LPRLPQWSAAGLNTAETGQRAAGLSQIWSRQLGRAIGPDSSLLGEGIGSLDLIRILPE
                     TRRYLGWRLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQR
                     RLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVPR
                     QLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTWLFRIADDEH
                     VLVAVAHHIAADGWSVAPLTADLSAAYASRCAGRAPDWAPLPVQYVDYTLWQREILGD
                     LDDSDSPIAAQLAYWENALAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVR
                     RIARQHNATSFMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVL
                     RVNLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQ
                     DNPVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYRTDVFEA
                     QAIDVLIERLRKVLVAVAAAPERTVSSIDALDGTERARLDEWGNRAVLTAPAPTPVSI
                     PQMLAAQVARIPEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERC
                     APAVVAMVAVLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPI
                     IDVVDALAAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLS
                     AAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVLTQ
                     TPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPL
                     RPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAGAGVGVGYWRRAGLTASRF
                     VACPFGGSGARMYRTGDLVCWRADGQLEFLGRTDDQVKIRGYRIELGEVATALAELAG
                     VGQAVVIAREDRPGDKRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDAL
                     PLTVNGKLDHRALPAPEYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELG
                     GDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSDPRLVSVHGDN
                     PTEVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTGATGFLGRYLVLELLRRLD
                     VDGRLICLVRAESDEDARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGL
                     DQPMWRRLAETVDLIVDSAAMVNAFPYHELFGPNVAGTAELIRIALTTKLKPFTYVST
                     ADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVA
                     VFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLP
                     VTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRRIDDF
                     AEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSAPTDRFRAAVRAA
                     KVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL"
     gene            117711..119696
                     /locus_tag="Y980_0102"
     CDS             117711..119696
                     /locus_tag="Y980_0102"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00343"
                     /note="Rv0102, (MTCY251.21) Probable conserved integral
                     membrane protein, highly similar to
                     P53525|Y102_MYCLE|ML1998|NP_302349.1|NC_002677 possible
                     membrane protein from Mycobacterium leprae (659 aa). Also
                     similar to others e.g. CAC01497.1|AL391017 putative
                     integral membrane protein from Streptomyces coelicolor
                     (316 aa); etc. Contains PS00343 Gram-positive cocci
                     surface proteins 'anchoring' hexapeptide."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved integral membrane protein"
                     /protein_id="AJF01448.1"
                     /db_xref="GOA:P64689"
                     /db_xref="InterPro:IPR019108"
                     /db_xref="UniProtKB/Swiss-Prot:P64689"
                     /translation="MGTHGATKSATSAVPTPRSNSMAMVRLAIGLLGVCAVVAAFGLV
                     SGARRYAEAGNPYPGAFVSVAEPVGFFAASLAGALCLGALIHVVMTAKPEPDGLIDAA
                     AFRIHLLAERVSGLWLGLAATMVVIQAAHDTGVGPARLLASGALSDSVAASEMARGWI
                     VAAICALVVATALRLYTRWLGHVVLLVPTVLAVVATAVTGNPGQGPDHDYATSAAIVF
                     AVAFATLTGLKIAAALAGTTPSRAVLVTQVTCGALALAYGAMLLYLFIPGWAVDSDFA
                     RLGLLAGVILTSVWLFDCWRLLVRPPHAGRRRGGGSGAALAMMAAMASIAAMAVMTAP
                     RFLTHAFTAWDVFLGYELPQPPTIARVLTVWRFDSLIGAAGVVLAIGYAAGFAALRRR
                     GNSWPVGRLIAWLTGCAALVFTSGSGVRAYGSAMFSVHMAEHMTLNMFIPVLLVLGGP
                     VTLALRVLPVTGDGRPPGAREWLTWLLHSRVTTFLSHPITAFVLFVASPYIVYFTPLF
                     DTFVRYHWGHEFMAIHFLVVGYLFYWAIIGIDPGPRRLPYPGRIGLLFAVMPFHAFFG
                     IALMTMSSTVGATFYRSVNLPWLSSIIADQHLGGGIAWSLTELPVIMVIVALVTQWAR
                     QDRRVASREDRHADSDYADDELEAYNAMLRELSRMRR"
     gene            complement(119912..122170)
                     /gene="ctpB"
                     /locus_tag="Y980_0103c"
     CDS             complement(119912..122170)
                     /gene="ctpB"
                     /locus_tag="Y980_0103c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00154"
                     /inference="protein motif:PROSITE:PS01047"
                     /note="Rv0103c, (MTCY251.22c) Probable
                     ctpB,cation-transporting P-type ATPase B (transmembrane
                     protein), equivalent to CTPB_MYCLE|P46840
                     cation-transporting P-type ATPase B from Mycobacterium
                     leprae (750 aa). Also highly similar to others e.g.
                     CAB96031.1|AL360055 putative metal transporter ATPase from
                     Streptomyces coelicolor (753 aa); NP_241423.1|NC_002570
                     copper-transporting ATPase from Bacillus halodurans (806
                     aa); etc. Also highly similar to Z46257|MLACEA_7 aceA gene
                     for isocitrate L from Mycobacterium leprae (750 aa). And
                     similar to MTCY251.11 from Mycobacterium tuberculosis.
                     Contains PS01047 Heavy-metal-associated domain, PS00154
                     E1-E2 ATPases phosphorylation site. Belongs to the cation
                     transport ATPases family (E1-E2 ATPases), subfamily IB."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation-transporter P-type ATPase B
                     CtpB"
                     /protein_id="AJF01449.1"
                     /db_xref="GOA:Q10877"
                     /db_xref="InterPro:IPR000579"
                     /db_xref="InterPro:IPR001757"
                     /db_xref="InterPro:IPR006121"
                     /db_xref="InterPro:IPR008250"
                     /db_xref="InterPro:IPR017969"
                     /db_xref="InterPro:IPR018303"
                     /db_xref="InterPro:IPR023214"
                     /db_xref="InterPro:IPR023299"
                     /db_xref="InterPro:IPR027256"
                     /db_xref="UniProtKB/Swiss-Prot:Q10877"
                     /translation="MAAPVVGDADLQSVRRIRLDVLGMSCAACASRVETKLNKIPGVR
                     ASVNFATRVATIDAVGMAADELCGVVEKAGYHAAPHTETTVLDKRTKDPDGAHARRLL
                     RRLLVAAVLFVPLADLSTLFAIVPSARVPGWGYILTALAAPVVTWAAWPFHSVALRNA
                     RHRTTSMETLISVGIVAATAWSLSSVFGDQPPREGSGIWRAILNSDSIYLEVAAGVTV
                     FVLAGRYFEARAKSKAGSALRALAELGAKNVAVLLPDGAELVIPASELKKRQRFVTRP
                     GETIAADGVVVDGSAAIDMSAMTGEAKPVRAYPAASVVGGTVVMDGRLVIEATAVGAD
                     TQFAAMVRLVEQAQTQKARAQRLADHIAGVFVPVVFVIAGLAGAAWLVSGAGADRAFS
                     VTLGVLVIACPCALGLATPTAMMVASGRGAQLGIFIKGYRALETIRSIDTVVFDKTGT
                     LTVGQLAVSTVTMAGSGTSERDREEVLGLAAAVESASEHAMAAAIVAASPDPGPVNGF
                     VAVAGCGVSGEVGGHHVEVGKPSWITRTTPCHDAALVSARLDGESRGETVVFVSVDGV
                     VRAALTIADTLKDSAAAAVAALRSRGLRTILLTGDNRAAADAVAAQVGIDSAVADMLP
                     EGKVDVIQRLREEGHTVAMVGDGINDGPALVGADLGLAIGRGTDVALGAADIILVRDD
                     LNTVPQALDLARATMRTIRMNMIWAFGYNVAAIPIAAAGLLNPLIAGAAMAFSSFFVV
                     SNSLRLRNFGAQ"
     gene            122314..123828
                     /locus_tag="Y980_0104"
     CDS             122314..123828
                     /locus_tag="Y980_0104"
                     /note="Rv0104, (MTCY251.23) Conserved hypothetical
                     protein, showing weak similarity with other cAMP-dependent
                     protein kinases e.g. AAC37564.1|M65066 cAMP-dependent
                     protein kinase RI-beta regulatory subunit from Homo
                     sapiens (380 aa); etc."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01450.1"
                     /db_xref="GOA:Q10898"
                     /db_xref="InterPro:IPR000595"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR018490"
                     /db_xref="UniProtKB/Swiss-Prot:Q10898"
                     /translation="MTPVTTFPLVDAILAGRDRNLDGVILIAAQHLLQTTHAMLRSLF
                     RVGLDPRNVAVIGKCYSTHPGVVDAMRADGIYVDDCSDAYAPHESFDTQYTRHVERFF
                     AESWARLTAGRTARVVLLDDGGSLLAVAGAMLDASADVIGIEQTSAGYAKIVGCALGF
                     PVINIARSSAKLLYESPIIAARVTQTAFERTAGIDSSAAILITGAGAIGTALADVLRP
                     LHDRVDVYDTRSGCMTPIDLPNAIGGYDVIIGATGATSVPASMHELLRPGVLLMSASS
                     SDREFDAVALRRRTTPNPDCHADLRVADGSVDATLLNSGFPVNFDGSPMCGDASMALT
                     MALLAAAVLYASVAVADEMSSDHPHLGLIDQGDIVASFLNIDVPLQALSRLPLLSIDG
                     YRRLQVRSGYTLFRQGERADHFFVIESGELEALVDGKVILRLGAGDHFGEACLLGGMR
                     RIATVRACEPSVLWELDGKAFGDALHGDAAMREIAYGVARTRLMHAGASESLMV"
     gene            complement(123977..124261)
                     /gene="rpmB1"
                     /locus_tag="Y980_0105c"
     CDS             complement(123977..124261)
                     /gene="rpmB1"
                     /locus_tag="Y980_0105c"
                     /note="Rv0105c, (MTCY251.24c) rpmB1, 50S ribosomal protein
                     L28-1, highly similar to others e.g. Q9X8K8|R28B_STRCO 50S
                     ribosomal protein L28-2 from Streptomyces coelicolor (78
                     aa); RL28_ECOLI|P02428 50s ribosomal protein l28 from
                     Escherichia coli (77 aa); etc. Also similar to MTCY63A_2
                     from Mycobacterium tuberculosis. Belongs to the L28P
                     family of ribosomal proteins."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28-1 RpmB1"
                     /protein_id="AJF01451.1"
                     /db_xref="GOA:P0A5V6"
                     /db_xref="InterPro:IPR001383"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5V6"
                     /translation="MSARCQITGRTVGFGKAVSHSHRRTRRRWPPNIQLKAYYLPSED
                     RRIKVRVSAQGIKVIDRDGHRGRRRAARAGSAPAHFARQAGSSLRTAAIL"
     gene            124371..125567
                     /locus_tag="Y980_0106"
     CDS             124371..125567
                     /locus_tag="Y980_0106"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0106, (MTCY251.25) Conserved hypothetical
                     protein, similar to others e.g. AL049841|SCE9_33 from
                     Streptomyces coelicolor (370 aa); etc. Some similarity to
                     P94400 homologue to nitrile hydratase region from Bacillus
                     subtilis (397 aa). Also similar to COBW_PSEDE|P29937; and
                     P47K_PSECL|P31521 47 kDa protein (p47k) (419 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01452.1"
                     /db_xref="InterPro:IPR003495"
                     /db_xref="InterPro:IPR011629"
                     /db_xref="UniProtKB/Swiss-Prot:P64691"
                     /translation="MRTPVILVAGQDHTDEVTGALLRRTGTVVVEHRFDGHVVRRMTA
                     TLSRGELITTEDALEFAHGCVSCTIRDDLLVLLRRLHRRDNVGRIVVHLAPWLEPQPI
                     CWAIDHVRVCVGHGYPDGPAALDVRVAAVVTCVDCVRWLPQSLGEDELPDGRTVAQVT
                     VGQAEFADLLVLTHPEPVAVAVLRRLAPRARITGGVDRVELALAHLDDNSRRGRTDTP
                     HTPLLAGLPPLAADGEVAIVEFSARRPFHPQRLHAAVDLLLDGVVRTRGRLWLANRPD
                     QVMWLESAGGGLRVASAGKWLAAMAASEVAYVDLERRLFADLMWVYPFGDRHTAMTVL
                     VCGADPTDIVNALNAALLSDDEMASPQRWQSYVDPFGDWHDDPCHEMPDAAGEFSAHR
                     NSGESR"
     gene            complement(125640..130538)
                     /gene="ctpI"
                     /locus_tag="Y980_0107c"
     CDS             complement(125640..130538)
                     /gene="ctpI"
                     /locus_tag="Y980_0107c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00154"
                     /note="Rv0107c, (MTCY251.26c, MTV031.01c) Probable ctpI,
                     cation-transporting ATPase I P-type, highly similar to
                     NP_302704.1|NC_002677 probable cation transport ATPase
                     from Mycobacterium leprae (1609 aa); and similar to others
                     e.g. CAB69720.1|AL137166 putative transport ATPase from
                     Streptomyces coelicolor (1472 aa); ATA1_SYNY|P37367
                     cation-transporting ATPase pma1 from Synechocystis sp.
                     (915 aa); etc. Also similar to MTCY39.21c and
                     MTCY22G10.22c from Mycobacterium tuberculosis. Contains
                     PS00154 E1-E2 ATPases phosphorylation site. Belongs to the
                     cation transport ATPases family (E1-E2 ATPases)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation-transporter ATPase I CtpI"
                     /protein_id="AJF01453.1"
                     /db_xref="GOA:Q10900"
                     /db_xref="InterPro:IPR001757"
                     /db_xref="InterPro:IPR006068"
                     /db_xref="InterPro:IPR008250"
                     /db_xref="InterPro:IPR018303"
                     /db_xref="InterPro:IPR023214"
                     /db_xref="InterPro:IPR023298"
                     /db_xref="InterPro:IPR023299"
                     /db_xref="UniProtKB/Swiss-Prot:Q10900"
                     /translation="MKIPGVATVLGGVTNGVAQTVRAGARLPGSAAAAVQTLASPVLE
                     LTGPVVQSVVQTTGRAIGVRGSHNESPDGMTPPVRWRSGRRVHFDLDPLLPFPRWHEH
                     AAMVEEPVRRIPGVAEAHVEGSLGRLVVELEPDADSDIAVDEVRDVVSAVAADIFLAG
                     SVSSPNSAPFADPGNPLAILVPLTAAAMDLVAMGATVTGWVARLPAAPQTTRALAALI
                     NHQPRMVSLMESRLGRVGTDIALAATTAAANGLTQSLGTPLLDLVQRSLQISEAAAHR
                     RVWRDREPALASPRRPQAPVVPIISSAGAKSQEPRHSWAAAAAGEASHVVVGGSIDAA
                     IDTAKGSRAGPVEQYVNQAANGSLIAAASALVAGGGTEDAAGAILAGVPRAAHMGRQA
                     FAAVLGRGLANTGQLVLDPGALRRLDRVRVVVIDGAALRGDNRAVLHAQGDEPGWDDD
                     RVYEVADALLHGEQAPEPDPDELPATGARLRWAPAQGPSATPAQGLEHADLVVDGQCV
                     GSVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTEDLSASVGSTHPPGTPLLKLVRE
                     LRADRGPVLLITAVHRDFASTDTLAALAIADVGVALDDPRGATPWTADLITGTDLAAA
                     VRILSALPVARAASESAVHLAQGGTTLAGLLLVTGEQDKTTNPASFRRWLNPVNAAAA
                     TALVSGMWSAAKVLRMPDPTPQPLTAWHALDPEIVYSRLAGGSRPLAVEPGIPAWRRI
                     LDDLSYEPVMAPLRGPARTLAQLAVATRHELADPLTPILAVGAAASAIVGSNIDALLV
                     AGVMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVVPAVATTRRRLEAARHATRTA
                     TVSAKSLRVGDVIDLAAPEVVPADARLLVAEDLEVDESFLTGESLPVDKQVDPVAVND
                     PDRASMLFEGSTIVAGHARAIVVATGVGTAAHRAISAVADVETAAGVQARLRELTSKV
                     LPMTLAGGAAVTALALLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRLTA
                     RGALVRSPRTIEALGRVDTICFDKTGTLTENRLRVVCALPSSTAAERDPLPQTTDAPS
                     AEVLRAAARASTQPHNGEGHAHATDEAILAAASALAGSLSSQGDSEWVVLAEVPFESS
                     RGYAAAIGRVGTDGIPMLMLKGAPETILPRCRLADPGVDHEHAESVVRHLAEQGLRVL
                     AVAQRTWDNGTTHDDETDADAVDAVAHDLELIGYVGLADTARSSSRPLIEALLDAERN
                     VVLITGDHPITARAIARQLGLPADARVVTGAELAVLDEEAHAKLAADMQVFARVSPEQ
                     KVQIVAALQRCGRVTAMVGDGANDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDL
                     GVLLDALVEGRSMWAGVRDAVTILVGGNVGEVLFTVIGTAFGAGRAPVGTRQLLLVNL
                     LTDMFPALAVAVTSQFAEPDDAEYPTDDAAERAQREHRRAVLIGPTPSLDAPLLRQIV
                     NRGVVTAAGATAAWAIGRWTPGTERRTATMGLTALVMTQLAQTLLTRRHSPLVIATAL
                     GSAGVLVGIIQTPVISHFSGVPRWDRSPGRASSAPRQEPPQSQRWHRSGWQAQSVSCN
                     LMNALTTRKTLTRVDRTYRRPR"
     gene            complement(130892..131101)
                     /locus_tag="Y980_0108c"
     CDS             complement(130892..131101)
                     /locus_tag="Y980_0108c"
                     /note="Rv0108c, (MTV031.02c) Hypothetical unknown
                     protein."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /protein_id="AJF01454.1"
                     /db_xref="UniProtKB/TrEMBL:L0T4C1"
                     /translation="MVPVETLHSGDPITDVNGGGQRYIVLESKTVGDSCVVLELESRV
                     NHQLQVIEKSFPAGYHVGRAHHRIL"
     gene            131380..132870
                     /gene="PE_PGRS1"
                     /locus_tag="Y980_0109"
     CDS             131380..132870
                     /gene="PE_PGRS1"
                     /locus_tag="Y980_0109"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0109, (MTV031.03c) PE_PGRS1, Member of the M.
                     tuberculosis PE family, PGRS subfamily of gly-rich
                     proteins (see Brennan and Delogu, 2002), highly similar to
                     many e.g. Q50615|Y0DP_MYCTU hypothetical glycine-rich 40.8
                     kDa protein from Mycobacterium tuberculosis (498 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="PE-PGRS family protein PE_PGRS1"
                     /protein_id="AJF01455.1"
                     /db_xref="InterPro:IPR000084"
                     /db_xref="UniProtKB/TrEMBL:L0T2H7"
                     /translation="MSLLITSPATVAAAATHLAGIGSALSTANAAAAAPTTALSVAGA
                     DEVSVLIAALFEAYAQEYQALSAQALAFHDQFVQALNMGAVCYAAAETANATPLQALQ
                     TVQQNVLTVVNAPTQALLGRPIIGNGANGLPNTGQDGGPGGLLFGNGGNGGSGGVDQA
                     GGNGGAAGLIGNGGSGGVGGPGIAGSAGGAGGAGGLLFGNGGPGGAGGIGTTGDGGPG
                     GAGGNAIGLFGSGGTGGMGGVGGMGGVGNGGNAGNGGTAGLFGHGGAGGAGGIGSADG
                     GLGGGGGNGRFMGNGGVGGAGGYGASGDGGNAGNGGLGGVFGDGGAGGTGGLGDVNGG
                     LAGIGGNAGFVGNGGAGGNGQLGSGAVSSAGGMGGNGGLVFGNGGPGGLGGPGTSAGN
                     GGMGGNAVGLFGQGGAGGAGGSGFGAGIPGGRGGDGGSGGLIGDGGTGGGAGAGDAAA
                     SAGGNGGNARLIGNGGDGGPGMFGGPGGAGGSGGTIFGFAGTPGPS"
     gene            133018..133767
                     /locus_tag="Y980_0110"
     CDS             133018..133767
                     /locus_tag="Y980_0110"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0110, (MTV031.04) Probable conserved integral
                     membrane protein, similar to many e.g. AL079308|SCH69_25
                     from Streptomyces coelicolor (297 aa); P54493|YQGP_BACSU
                     hypothetical 56.4 KD protein from Bacillus subtilis (507
                     aa); etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved integral membrane protein"
                     /protein_id="AJF01456.1"
                     /db_xref="GOA:L0T2M4"
                     /db_xref="InterPro:IPR002610"
                     /db_xref="InterPro:IPR022764"
                     /db_xref="UniProtKB/TrEMBL:L0T2M4"
                     /translation="MRVGPVGHQCAECVREGARAVRQPRTPFGGRQRSATPVVTYTLI
                     SLNALVFVMQVTVMGLERQLALWPPAVASGQTYRLVTSAFLHYGAMHLLLNMWALYVV
                     GPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGLFGATFMVARR
                     LHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVYAPRERRNLIQAT
                     VTITVLVAFVVLIGWRTVDLLALFGGRLNLS"
     gene            133948..136005
                     /locus_tag="Y980_0111"
     CDS             133948..136005
                     /locus_tag="Y980_0111"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0111, (MTV031.05) Possible transmembrane
                     acyltransferase, equivalent to AA22904.1|AL035300 putative
                     acyltransferase from Mycobacterium leprae (696 aa). Also
                     similar to others e.g. C69975 acyltransferase homolog yrhL
                     from Bacillus subtilis (634 aa). Very similar to
                     Mycobacterium tuberculosis proteins Rv0228, Rv1254,
                     Rv1565c, etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane acyltransferase"
                     /protein_id="AJF01457.1"
                     /db_xref="GOA:L0T5Q0"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="InterPro:IPR013831"
                     /db_xref="UniProtKB/TrEMBL:L0T5Q0"
                     /translation="MPARSVPRPRWVAPVRRVGRLAVWDRPERRSGIPALDGLRAIAV
                     ALVLASHGGIPGMGGGFIGVDAFFVLSGFLITSLLLDELGRTGRIDLSGFWIRRARRL
                     LPALVLMVLTVSAARALFPDQALTGLRSDAIAAFLWTANWRFVAQNTDYFTQGAPPSP
                     LQHTWSLGVEEQYYVVWPLLLIGATLLLAARARRRCRRATVGGVRFAAFLIASLGTMA
                     SATAAVAFTSAATRDRIYFGTDTRAQALLIGSAAAALLVRDWPSLNRGWCLIRTRWGR
                     RIARLLPFVGLAGLAVTTHVATGSVGEFRHGLLIVVAGAAVIVVASVAMEQRGAVARI
                     LAWRPLVWLGTISYGVYLWHWPIFLALNGQRTGWSGPALFAARCAATVVLAGASWWLI
                     EQPIRRWRPARVPLLPLAAATVASAAAVTMLVVPVGAGPGLREIGLPPGVSAVAAVSP
                     SPPEASQPAPGPRDPNRPFTVSVFGDSIGWTLMHYLPPTPGFRFIDHTVIGCSLVRGT
                     PYRYIGQTLEQRAECDGWPARWSAQVNRDQPDVALLIVGRWETVDRVNEGRWTHIGDP
                     TFDAYLNAELQRALSIVGSTGVRVMVTTVPYSRGGEKPDGRLYPEDQPERVNKWNAML
                     HNAISQHSNVGMIDLNKKLCPDGVYTAKVDGIKVRSDGVHLTQEGVKWLIPWLEDSVR
                     VAS"
     gene            136287..137243
                     /gene="gca"
                     /locus_tag="Y980_0112"
     CDS             136287..137243
                     /gene="gca"
                     /locus_tag="Y980_0112"
                     /inference="protein motif:PROSITE:PS00061"
                     /note="Rv0112, (MTV031.06) Possible gca,GDP-mannose
                     4,6-dehydratase, similar to others e g. U18320|PAU18320_1
                     GDP-D-mann from Pseudomonas aeruginosa (323 aa). Similar
                     to Rv3634c, Rv3784,etc from Mycobacterium tuberculosis.
                     Contains PS00061 Short-chain dehydrogenases/reductases
                     family signature. Seems to belong to the GDP-mannose
                     4,6-dehydratase family. Cofactor: NAD(+). This region is a
                     possible MT-complex-specific genomic island (See Becq et
                     al.,2007)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative GDP-mannose 4,6-dehydratase Gca
                     (GDP-D-mannose dehydratase)"
                     /protein_id="AJF01458.1"
                     /db_xref="GOA:L7N5R0"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="UniProtKB/TrEMBL:L7N5R0"
                     /translation="MKVWITGAGGMMGSHLAEMLLAAGHDVYATYCRPTIDPSDLQFN
                     GAEVDITDWCSVYDSIATFRPDAVFHLAAQSYPAVSWARPVETLTTNMVGTAIVFEAL
                     RRVRPHAKIIVAGSSAEYGFVDPSEVPINERRELRPLHPYGVSKAATDMLAYQYHKSY
                     GMHTVVARIFNCTGPRKVGDALSDFVRRCTWLEHHPEQSAIRVGNLKTKRTIVDVRDL
                     NRALMLMLDKGEAGADYNVGGSIAYEMGDVLKQVIAACKRDDIVPEVDPALLRPTDEK
                     IIYGDCSKLAAITGWQQEICLTQTIADMFDYWRSKSESALMV"
     gene            137317..137907
                     /gene="gmhA"
                     /locus_tag="Y980_0113"
                     /gene_synonym="lpcA"
     CDS             137317..137907
                     /gene="gmhA"
                     /locus_tag="Y980_0113"
                     /gene_synonym="lpcA"
                     /note="Rv0113, (MTV031.07) Probable gmhA (alternate gene
                     name: lpcA), sedoheptulose-7-phosphate isomerase (see
                     citation below), similar to many e.g. AE0005|HPAE000596_11
                     from Helicobacter pylori (192 aa). Belongs to the sis
                     family, LPCA subfamily. This region is a possible
                     MT-complex-specific genomic island (See Becq et al.,
                     2007)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sedoheptulose-7-phosphate isomerase
                     GmhA (phosphoheptose isomerase)"
                     /protein_id="AJF01459.1"
                     /db_xref="GOA:P0A604"
                     /db_xref="InterPro:IPR001347"
                     /db_xref="InterPro:IPR004515"
                     /db_xref="UniProtKB/Swiss-Prot:P0A604"
                     /translation="MCTARTAEEIFVETIAVKTRILNDRVLLEAARAIGDRLIAGYRA
                     GARVFMCGNGGSAADAQHFAAELTGHLIFDRPPLGAEALHANSSHLTAVANDYDYDTV
                     FARALEGSARPGDTLFAISTSGNSMSVLRAAKTARELGVTVVAMTGESGGQLAEFADF
                     LINVPSRDTGRIQESHIVFIHAISEHVEHALFAPRQ"
     gene            137939..138511
                     /gene="gmhB"
                     /locus_tag="Y980_0114"
     CDS             137939..138511
                     /gene="gmhB"
                     /locus_tag="Y980_0114"
                     /note="Rv0114, (MTV031.08) Possible
                     gmhB,D-alpha,beta-D-heptose-1,7-biphosphate phosphatase
                     (see citation below), similar to several hypothetical
                     proteins and phosphatases e.g. HIS7_ECOLI|P06987
                     imidazoleglycerol-phosphate dehydratase (355 aa). This
                     region is a possible MT-complex-specific genomic island
                     (See Becq et al., 2007)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative D-alpha,beta-D-heptose-1,7-biphosphate
                     phosphatase GmhB (D-glycero-D-manno-heptose 7-phosphate
                     kinase)"
                     /protein_id="AJF01460.1"
                     /db_xref="GOA:O53636"
                     /db_xref="InterPro:IPR004446"
                     /db_xref="InterPro:IPR006543"
                     /db_xref="InterPro:IPR006549"
                     /db_xref="InterPro:IPR023214"
                     /db_xref="UniProtKB/Swiss-Prot:O53636"
                     /translation="MVAERAGHQWCLFLDRDGVINRQVVGDYVRNWRQFEWLPGAARA
                     LKKLRAWAPYIVVVTNQQGVGAGLMSAVDVMVIHRHLQMQLASDGVLIDGFQVCPHHR
                     SQRCGCRKPRPGLVLDWLGRHPDSEPLLSIVVGDSLSDLELAHNVAAAAGACASVQIG
                     GASSGGVADASFDSLWEFAVAVGHARGERG"
     gene            138511..139671
                     /gene="hddA"
                     /locus_tag="Y980_0115"
     CDS             138511..139671
                     /gene="hddA"
                     /locus_tag="Y980_0115"
                     /inference="protein motif:PROSITE:PS00435"
                     /note="Rv0115, (MTV031.09) Possible
                     hddA,D-alpha-D-heptose-7-phosphate kinase (see citation
                     below),similar to several hypothetical proteins and sugar
                     kinases e.g. AAK27850.1|AF324836_3
                     D-glycero-D-manno-heptose 7-phosphate kinase from
                     Aneurinibacillus thermoaerophilus (341 aa);
                     AAK80995.1|AE007802_11 Sugar kinase from Clostridium
                     acetobutylicum (364 aa). This region is a possible
                     MT-complex-specific genomic island (See Becq et al.,
                     2007)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative D-alpha-D-heptose-7-phosphate kinase
                     HddA"
                     /protein_id="AJF01461.1"
                     /db_xref="GOA:L7N4E0"
                     /db_xref="InterPro:IPR001174"
                     /db_xref="InterPro:IPR006204"
                     /db_xref="InterPro:IPR013750"
                     /db_xref="InterPro:IPR014606"
                     /db_xref="InterPro:IPR014721"
                     /db_xref="InterPro:IPR020568"
                     /db_xref="UniProtKB/TrEMBL:L7N4E0"
                     /translation="MAILRGRAPLRLGLGGGGTDVEPYSSQFGGRILSVTIDKYAYAF
                     AERGTGDEIAFRSPDRDRAGQASIDDLASLEEDFPLHVAVYRRVIAEFNGGTPFPLQL
                     ATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGWQ
                     DHYAAAFGGFNFMESRPNGEVVVNPLRIRREVIAELEASLLLYFGGVSRLSSEVIADQ
                     QRNVVERDADALAATHSICAEALEMKDLLVVGDIPGFADSLLRGWQAKKRTSTRISNP
                     AIEHAYQVAQSSGMVAGKVSGAGGGGFLMMIVDPRRRIEVARSLERECGGSVAPCLFT
                     KGGAVTWHIPESTAPVRRGVADAVASALGNAGILLCAGCVLATSHSTWRVPV"
     gene            complement(140265..141020)
                     /gene="ldtA"
                     /locus_tag="Y980_0116c"
     CDS             complement(140265..141020)
                     /gene="ldtA"
                     /locus_tag="Y980_0116c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0116c, (MTV031.10c) Probable
                     ldtA,L,D-transpeptidase, showing similarity to several
                     hypothetical mycobacterial proteins e.g. Rv1433 from
                     Mycobacterium tuberculosis (271 aa); and
                     Q49706|B1496_F2_81|U00013 from Mycobacterium leprae (271
                     aa); to the C-terminal regions of others like Rv0192 from
                     Mycobacterium tuberculosis (366 aa); and
                     Rv0192|Z97050|MTCI28_32 from Mycobacterium tuberculosis
                     cosmid (366 aa). Predicted to be an outer membrane protein
                     (See Song et al., 2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative L,D-transpeptidase LdtA"
                     /protein_id="AJF01462.1"
                     /db_xref="GOA:L0T5Q5"
                     /db_xref="InterPro:IPR005490"
                     /db_xref="UniProtKB/TrEMBL:L0T5Q5"
                     /translation="MRRVVRYLSVVVAITLMLTAESVSIATAAVPPLQPIPGVASVSP
                     ANGAVVGVAHPVVVTFTTPVTDRRAVERSIRISTPHNTTGHFEWVASNVVRWVPHRYW
                     PPHTRVSVGVQELTEGFETGDALIGVASISAHTFTVSRNGEVLRTMPASLGKPSRPTP
                     IGSFHAMSKERTVVMDSRTIGIPLNSSDGYLLTAHYAVRVTWSGVYVHSAPWSVNSQG
                     YANVSHGCINLSPDNAAWYFDAVTVGDPIEVVG"
     gene            141198..142142
                     /gene="oxyS"
                     /locus_tag="Y980_0117"
     CDS             141198..142142
                     /gene="oxyS"
                     /locus_tag="Y980_0117"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00044"
                     /note="Rv0117, (MTV031.11) OxyS, oxidative stress response
                     protein regulatory protein, LysR family (see citation
                     below). Similar to many transcription regulators and OxyR,
                     the oxidative stress response protein of many bacteria.
                     Contains LysR family signature at N-terminus. Also
                     contains helix-turn-helix motif at aa 16-37 (Score 1543,
                     +4.44 SD). Belongs to the LysR family of transcriptional
                     regulators. OXYR is required for the induction of a
                     regulon of hydrogen peroxide inducible genes such as
                     catalase, glutathione-reductase, etc."
                     /codon_start=1
                     /transl_table=11
                     /product="Oxidative stress response regulatory protein
                     OxyS"
                     /protein_id="AJF01463.1"
                     /db_xref="GOA:O33175"
                     /db_xref="HSSP:Q9WXC7"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:O33175"
                     /translation="MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELN
                     VTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVDAVRSGITGTLRLGTVPTAS
                     TTASLVLSAFCSAHPLAKVQVCSRLAATELYRRLREFELDAVIVHPETQDSDDVDLVP
                     LYEEQYVLLSPADMLPPGTSTLVWRDAAQLPLALLTADMRDRQVIDAAFADHAVSAIP
                     QVETDSVASLFAQVATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALA
                     TNALGPGSPVARALITCAQALALNEFFDTQLRGITRRR"
     gene            complement(142126..143874)
                     /gene="oxcA"
                     /locus_tag="Y980_0118c"
     CDS             complement(142126..143874)
                     /gene="oxcA"
                     /locus_tag="Y980_0118c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0118c, (MTV031.12c), Len: 582 aa. Probable
                     oxcA,oxalyl-CoA decarboxylase, highly similar to many e.g.
                     P78093|OXC_ECOLI|7449483|B65011|YFDU|B2373|Z3637|ECS325
                     probable oxalyl-CoA decarboxylase from Escherichia coli
                     (564 aa); M77128|OXAOXA_1 oxalyl-CoA decarboxylase from
                     Oxalobacter formigenes (568 aa). Also similar to
                     mycobacterial IlvB proteins e.g. MLCB1788.46c unknown
                     TPP-requiring enzyme from Mycobacterium leprae (548 aa);
                     and AL0086|MLCB1788_19 from Mycobacterium leprae (548
                     aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxalyl-CoA decarboxylase OxcA"
                     /protein_id="AJF01464.1"
                     /db_xref="GOA:L7N5Z3"
                     /db_xref="InterPro:IPR011766"
                     /db_xref="InterPro:IPR012000"
                     /db_xref="InterPro:IPR012001"
                     /db_xref="InterPro:IPR017660"
                     /db_xref="UniProtKB/TrEMBL:L7N5Z3"
                     /translation="MTTRSASPCTVLTDGCHLVVDALKANDVDTIYGVVGIPITDLAR
                     AAQASGIRYIGFRHEASAGNAAAAAGFLTARPGVCLTTSGPGFLNGLPALANATTNCF
                     PMIQISGSSSRPMVDLQRGDYQDLDQLNAARPFVKAAYRIGQVQDIGRGVARAIRTAT
                     SGRPGGVYLDIPGDVLGQAVEASAASGAIWRPVDPAPRLLPAPEAIDRALDVLAQAQR
                     PLLVLSKGAAYAQADNVIREFVEHTGIPFLPMSMAKGLLPDSHPQSAAAARSLAMARA
                     DVVLLVGARLNWLLGNGESPQWSADAKFIQVDIEASEFDSNRPIVAPLTGDIGSVMSA
                     LLEAAADRSSVASAAWTGELADRKARNSAKMRRRLADDHHPMRFYNALGAIRSVLQRN
                     PDVYVVNEGANALDLARNIIDMHLPRHRLDSGTWGVMGIGMGYAIAAAVETGRPVVAI
                     EGDSAFGFSGMEFETICRYRLPVTVVILNNGGVYRGDEATIFRSAAPVWRHDPAPTVL
                     NAHARHELIAEAFGGKGYHVSTPTELESALTDALASNGPSLIDCELDPADGVESGHLA
                     KLNTTSAATPAISGDG"
     gene            144047..145624
                     /gene="fadD7"
                     /locus_tag="Y980_0119"
     CDS             144047..145624
                     /gene="fadD7"
                     /locus_tag="Y980_0119"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00455"
                     /note="Rv0119, (MTV031.13-MTCI418B.01) Probable fadD7,
                     fatty-acid-CoA synthetase, similar to 4-coumarate:CoA
                     ligase of many organisms e.g. U39405|PTU39405_1
                     4-coumarate:CoA ligase from Pinus taedaxylem (537 aa).
                     Contains PS00455 Putative AMP-binding domain signature."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fatty-acid-CoA ligase FadD7
                     (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)"
                     /protein_id="AJF01465.1"
                     /db_xref="GOA:L0T2J0"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="UniProtKB/TrEMBL:L0T2J0"
                     /translation="MASDFGPRIADLVEVAATRLPEAPALVVTADRIAISHRDLARLV
                     DELAGQLTRSGLLPGDRVALRMGSNAEFVVALLAASRADLVVVPLDPALPITEQRVRS
                     QAAGARVVLIDADGPHDRAEPTTRWWPLTVNVGGDSGPSGGTLSVHLDAATEPNPATS
                     TPEGLRPDDAMIMFTGGTTGLPKMVPWTHANIASSVRAIITGYRLSPRDATVAVMPLY
                     HGHGLIASLLATLASGGAVSLPARGRFSAHTFWDDIKAVGATWYTAVPTIHQILLERS
                     ATEPSGRKPAALRFIRSCSAPLTAQAALALQTEFAAPVVCAFGMTEATHQVTTTQIEG
                     IDQTETPVVSTGLVGRSTGAQIRIVGSDGLPLPAGAVGEIWLRGTTVVRGYLGDPTIT
                     AANFTDGWLRTGDLGSLSAAGDLSIRGRIKELINRGGEKISPERVEGVLASHPNVMEA
                     AVFGVPHQLYGEAVAAVIVPRESAPPTREELVQFCRERLAAFEIPASFQEASGLPHTA
                     KGSLDRRAVAERFGHSV"
     gene            complement(145625..147769)
                     /gene="fusA2"
                     /locus_tag="Y980_0120c"
                     /gene_synonym="fus2"
     CDS             complement(145625..147769)
                     /gene="fusA2"
                     /locus_tag="Y980_0120c"
                     /gene_synonym="fus2"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00017"
                     /note="Rv0120c, (MTCI418B.02c) Probable fusA2 (alternate
                     gene name: fus2), elongation factor G, highly similar to
                     others e.g. EFG_ECOLI|P02996 elongation factor G (ef-g)
                     from Escherichia coli (703 aa). Also similar to
                     fusA1|MTCY210.01 from Mycobacterium tuberculosis; and
                     P30767|EFG_MYCLE elongation factor G (EF-G) from
                     Mycobacterium leprae (701 aa). Contains PS00017
                     ATP/GTP-binding site motif A (P-loop). Belongs to the
                     GTP-binding elongation factor family, EF-G/EF-2
                     subfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="putative elongation factor G FusA2 (EF-G)"
                     /protein_id="AJF01466.1"
                     /db_xref="GOA:O07170"
                     /db_xref="InterPro:IPR000640"
                     /db_xref="InterPro:IPR000795"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR004161"
                     /db_xref="InterPro:IPR005225"
                     /db_xref="InterPro:IPR005517"
                     /db_xref="InterPro:IPR009000"
                     /db_xref="InterPro:IPR009022"
                     /db_xref="InterPro:IPR014721"
                     /db_xref="InterPro:IPR020568"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/Swiss-Prot:O07170"
                     /translation="MADRVNASQGAAAAPTANGPGGVRNVVLVGPSGGGKTTLIEALL
                     VAAKVLSRPGSVTEGTTVCDFDEAEIRQQRSVGLAVASLAYDGIKVNLVDTPGYADFV
                     GELRAGLRAADCALFVIAANEGVDEPTKSLWQECSQVGMPRAVVITKLDHARANYREA
                     LTAAQDAFGDKVLPLYLPSGDGLIGLLSQALYEYADGKRTTRTPAESDTERIEEARGA
                     LIEGIIEESEDESLMERYLGGETIDESVLIQDLEKAVARGSFFPVIPVCSSTGVGTLE
                     LLEVATRGFPSPMEHPLPEVFTPQGVPHAELACDNDAPLLAEVVKTTSDPYVGRVSLV
                     RVFSGTIRPDTTVHVSGHFSSFFGGGTSNTHPDHDEDERIGVLSFPLGKQQRPAAAVV
                     AGDICAIGKLSRAETGDTLSDKAEPLVLKPWTMPEPLLPIAIAAHAKTDEDKLSVGLG
                     RLAAEDPTLRIEQNQETHQVVLWCMGEAHAGVVLDTLANRYGVSVDTIELRVPLRETF
                     AGNAKGHGRHIKQSGGHGQYGVCDIEVEPLPEGSGFEFLDKVVGGAVPRQFIPNVEKG
                     VRAQMDKGVHAGYPVVDIRVTLLDGKAHSVDSSDFAFQMAGALALREAAAATKVILLE
                     PIDEISVLVPDDFVGAVLGDLSSRRGRVLGTETAGHDRTVIKAEVPQVELTRYAIDLR
                     SLAHGAASFTRSFARYEPMPESAAARVKAGAG"
     gene            complement(147906..148340)
                     /locus_tag="Y980_0121c"
     CDS             complement(147906..148340)
                     /locus_tag="Y980_0121c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0121c, (MTCI418B.03c) Conserved protein, showing
                     some similarity with others proteins from Mycobacterium
                     tuberculosis e.g. Rv1155, Rv1875, Rv2074,etc."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01467.1"
                     /db_xref="GOA:L0T5Q8"
                     /db_xref="InterPro:IPR011576"
                     /db_xref="InterPro:IPR012349"
                     /db_xref="InterPro:IPR019967"
                     /db_xref="UniProtKB/TrEMBL:L0T5Q8"
                     /translation="MGEFDPKLRFAQSPVARLATSTPDGTPHLVPVVFALGARRPAEA
                     TGADVIYTAVDAKRKTTQRLRRLANLEHNPRASVLVDSYADDWTQLWWVRADGVAAIH
                     RDGEVMRAAYRLLRAKYAQYQSVPLNGPVIAIAVQRWASWHA"
     gene            148489..148857
                     /locus_tag="Y980_0122"
     CDS             148489..148857
                     /locus_tag="Y980_0122"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0122, (MTCI418B.04) Hypothetical unknown
                     protein."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /protein_id="AJF01468.1"
                     /db_xref="UniProtKB/TrEMBL:L0T5K9"
                     /translation="MAGSVSAAAGIGWVGLNVTETNRDQCYRVERTTVDALTHPEYRV
                     HTRGVQRVRVTRNARKHRVSKHRIVAAMRHCGVPVIQEDGSLYYQGRDTSGRLTEVVA
                     VEADDGDLIITHAMPKEWKR"
     gene            148854..149222
                     /locus_tag="Y980_0123"
     CDS             148854..149222
                     /locus_tag="Y980_0123"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0123, (MTCI418B.05) Unknown protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01469.1"
                     /db_xref="GOA:L7N5Q9"
                     /db_xref="InterPro:IPR002145"
                     /db_xref="UniProtKB/TrEMBL:L7N5Q9"
                     /translation="MTKKPRNPADYVIGDDVEVSDVDLKQEEVYVDGERLTDERVEQM
                     ASESLRLAREREANLIPGGKSLSGGSAHSPAVQVVVSKATHAKLKELARSRKMSVSKL
                     LRPVLDEFVQRETGRILPRR"
     gene            149531..150994
                     /gene="PE_PGRS2"
                     /locus_tag="Y980_0124"
     CDS             149531..150994
                     /gene="PE_PGRS2"
                     /locus_tag="Y980_0124"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0124, (MTCI418B.06) PE_PGRS2, Member of the
                     Mycobacterium tuberculosis PE family, PGRS subfamily of
                     gly-rich proteins (see Brennan and Delogu, 2002), highly
                     similar to many e.g. Y0DP_MYCTU|Q50615 from Mycobacterium
                     tuberculosis (498 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="PE-PGRS family protein PE_PGRS2"
                     /protein_id="AJF01470.1"
                     /db_xref="InterPro:IPR000084"
                     /db_xref="UniProtKB/TrEMBL:L0T2J5"
                     /translation="MSFVSVAPEIVVAAATDLAGIGSAISAANAAAAAPTTAVLAAGA
                     DEVSAAIAALFSGHAQAYQALSAQAAAFHQQFVQTLAGGAGAYAAAEAQVEQQLLAAI
                     NAPTQALLGRPLIGNGADGAPGTGQAGGAGGILYGNGGNGGSGAAGQAGGAGGPAGLI
                     GHGGSGGAGGSGAAGGAGGHGGWLWGNGGVGGSGGAGVGAGVAGGHGGAGGAAGLWGA
                     GGGGGNGGNGADANIVSGGDGGLGGAGGGGGWLYGDGGAGGHGGQGAIGLGGGAGGDG
                     GQGGAGRGLWGTGGAGGHGGQGGGTGGPPLPGQAGMGAAGGAGGLIGNGGAGGDGGVG
                     ASGGVAGVGGAGGNAMLIGHGGAGGAGGDSSFANGAAGGAGGAGGHLFGNGGSGGHGG
                     AVTAGNTGIGGAGGVGGDARLIGHGGAGGAGGDRAGALVGRDGGPGGNGGAGGQLYGN
                     GGDGAPGTGGTLQAAVSGLVTALFGAPGQPGDTGQPG"
     gene            151146..152213
                     /gene="pepA"
                     /locus_tag="Y980_0125"
                     /gene_synonym="mtb32a"
     CDS             151146..152213
                     /gene="pepA"
                     /locus_tag="Y980_0125"
                     /gene_synonym="mtb32a"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00135"
                     /note="Rv0125, (MTCI418B.07, MTB32A) Probable pepA
                     (alternate gene name: mtb32a), serine protease (see Skeiky
                     et al., 1999), highly similar to other proteases e.g.
                     HHOB_ECOLI|P31137 protease hhob precursor (355 aa). Also
                     similar to Q50320 34 kDa protein precursor from
                     Mycobacterium tuberculosis (361 aa). Contains PS00135
                     Serine proteases, trypsin family, serine active site. Has
                     a putative signal sequence at the N-terminus. Belongs to
                     the serine protease family. Conserved in M. tuberculosis,
                     M. leprae, M. bovis and M. avium paratuberculosis;
                     predicted to be essential for in vivo survival and
                     pathogenicity (See Ribeiro-Guimaraes and Pessolani,
                     2007)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative serine protease PepA (serine
                     proteinase) (MTB32A)"
                     /protein_id="AJF01471.1"
                     /db_xref="GOA:L7N4F0"
                     /db_xref="InterPro:IPR001478"
                     /db_xref="InterPro:IPR001940"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="InterPro:IPR009003"
                     /db_xref="UniProtKB/TrEMBL:L7N4F0"
                     /translation="MSNSRRRSLRWSWLLSVLAAVGLGLATAPAQAAPPALSQDRFAD
                     FPALPLDPSAMVAQVGPQVVNINTKLGYNNAVGAGTGIVIDPNGVVLTNNHVIAGATD
                     INAFSVGSGQTYGVDVVGYDRTQDVAVLQLRGAGGLPSAAIGGGVAVGEPVVAMGNSG
                     GQGGTPRAVPGRVVALGQTVQASDSLTGAEETLNGLIQFDAAIQPGDSGGPVVNGLGQ
                     VVGMNTAASDNFQLSQGGQGFAIPIGQAMAIAGQIRSGGGSPTVHIGPTAFLGLGVVD
                     NNGNGARVQRVVGSAPAASLGISTGDVITAVDGAPINSATAMADALNGHHPGDVISVT
                     WQTKSGGTRTGNVTLAEGPPA"
     gene            152322..154127
                     /gene="treS"
                     /locus_tag="Y980_0126"
     CDS             152322..154127
                     /gene="treS"
                     /locus_tag="Y980_0126"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0126, (MTCI418B.08) TreS, trehalose synthase (see
                     citation below), highly similar to others e.g.
                     CAA04601.2|AJ001205 putative trehalose synthase from
                     Streptomyces coelicolor (566 aa);
                     S71450|1536814|BAA11303.1|D78198 trehalose synthase
                     maltose-specific from Pimelobacter sp. strain R48 (573
                     aa). Also similar to MAL1_DROME|P07191 possible maltase
                     precursor (508 aa); and similar to proteins associated
                     with amino-acid transport e.g. Q64319 rat protein which
                     stimulates transport of cystine and dibasic and neutral
                     amino acids (683 aa). Also similar to several other
                     Mycobacterium tuberculosis proteins e.g. Rv2471."
                     /codon_start=1
                     /transl_table=11
                     /product="Trehalose synthase TreS"
                     /protein_id="AJF01472.1"
                     /db_xref="GOA:O07176"
                     /db_xref="InterPro:IPR006047"
                     /db_xref="InterPro:IPR006589"
                     /db_xref="InterPro:IPR012810"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="InterPro:IPR013781"
                     /db_xref="InterPro:IPR015902"
                     /db_xref="InterPro:IPR017853"
                     /db_xref="InterPro:IPR022567"
                     /db_xref="UniProtKB/Swiss-Prot:O07176"
                     /translation="MNEAEHSVEHPPVQGSHVEGGVVEHPDAKDFGSAAALPADPTWF
                     KHAVFYEVLVRAFFDASADGSGDLRGLIDRLDYLQWLGIDCIWLPPFYDSPLRDGGYD
                     IRDFYKVLPEFGTVDDFVALVDAAHRRGIRIITDLVMNHTSESHPWFQESRRDPDGPY
                     GDYYVWSDTSERYTDARIIFVDTEESNWSFDPVRRQFYWHRFFSHQPDLNYDNPAVQE
                     AMIDVIRFWLGLGIDGFRLDAVPYLFEREGTNCENLPETHAFLKRVRKVVDDEFPGRV
                     LLAEANQWPGDVVEYFGDPNTGGDECHMAFHFPLMPRIFMAVRRESRFPISEIIAQTP
                     PIPDMAQWGIFLRNHDELTLEMVTDEERDYMYAEYAKDPRMKANVGIRRRLAPLLDND
                     RNQIELFTALLLSLPGSPVLYYGDEIGMGDVIWLGDRDGVRIPMQWTPDRNAGFSTAN
                     PGRLYLPPSQDPVYGYQAVNVEAQRDTSTSLLNFTRTMLAVRRRHPAFAVGAFQELGG
                     SNPSVLAYVRQVAGDDGDTVLCVNNLSRFPQPIELDLQQWTNYTPVELTGHVEFPRIG
                     QVPYLLTLPGHGFYWFQLTTHEVGAPPTCGGERRL"
     repeat_region   154071..154123
                     /gene="treS"
                     /locus_tag="Y980_0126"
                     /note="53 bp Mycobacterial Interspersed Repetitive
                     Unit,Class III (see Supply et al., 1997)"
     repeat_region   154124..154176
                     /note="53 bp Mycobacterial Interspersed Repetitive
                     Unit,Class II"
     repeat_region   154177..154229
                     /note="53 bp Mycobacterial Interspersed Repetitive
                     Unit,Class II"
     gene            154230..155597
                     /gene="mak"
                     /locus_tag="Y980_0127"
     CDS             154230..155597
                     /gene="mak"
                     /locus_tag="Y980_0127"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0127, (MTCI418B.09, MTCI5.01) Mak,maltokinase;
                     highly similar to various proteins e.g. AJ0012|SCJ001205_4
                     hypothetical protein from Streptomyces coelicolor A3(2)
                     (464 aa); AJ0012|SCJ001206_5 hypothetical protein from
                     Streptomyces coelicolor A3(2) (453 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="Maltokinase Mak"
                     /protein_id="AJF01473.1"
                     /db_xref="GOA:O07177"
                     /db_xref="InterPro:IPR002575"
                     /db_xref="UniProtKB/Swiss-Prot:O07177"
                     /translation="MTRSDTLATKLPWSDWLSRQRWYAGRNRELATVKPGVVVALRHN
                     LDLVLVDVTYTDGATERYQVLVGWDFEPASEYGTKAAIGVADDRTGFDALYDVAGPQF
                     LLSLIVSSAVCGTSTGEVTFTREPDVELPFAAQPRVCDAEQSNTSVIFDRRAILKVFR
                     RVSSGINPDIELNRVLTRAGNPHVARLLGAYQFGRPNRSPTDALAYALGMVTEYEANA
                     AEGWAMATASVRDLFAEGDLYAHEVGGDFAGESYRLGEAVASVHATLADSLGTAQATF
                     PVDRMLARLSSTVAVVPELREYAPTIEQQFQKLAAEAITVQRVHGDLHLGQVLRTPES
                     WLLIDFEGEPGQPLDERRAPDSPLRDVAGVLRSFEYAAYGPLVDQATDKQLAARAREW
                     VERNRAAFCDGYAVASGIDPRDSALLLGAYELDKAVYETGYETRHRPGWLPIPLRSIA
                     RLTAS"
     gene            155665..156444
                     /locus_tag="Y980_0128"
     CDS             155665..156444
                     /locus_tag="Y980_0128"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0128, (MTCI5.02) Probable conserved transmembrane
                     protein, with some similarity to Rv3064c and other
                     bacterial proteins e.g. AAK85977.1|AE007957|AGR_C_254p
                     from Agrobacterium tumefaciens (206 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01474.1"
                     /db_xref="GOA:L7N4E6"
                     /db_xref="InterPro:IPR010699"
                     /db_xref="UniProtKB/TrEMBL:L7N4E6"
                     /translation="MQREIYDGEARLSWVLAALAGILGATAFTHSAGYFVTFMTGNSQ
                     RAVLGLFGDDAWMSVTASLLILFFVAGVVIASVCRRHFWAAHPHGPTVLTTFSLIFAA
                     GVDIMLGGWHESMLDFVPILFVVFGIGALNTSFVKDGEVSVPLSYVTGTLVKMGQGIE
                     RHLAGGKVEDWLGYFLLHASFVLGAAAGGAISMVVTGPQMLAVAAVVCAATTGYTYLH
                     ADRRGLVNQKRPQPGKRLFRALRRGELDSGTSTPATNYGSS"
     gene            complement(156576..157598)
                     /gene="fbpC"
                     /locus_tag="Y980_0129c"
                     /gene_synonym="85C"
                     /gene_synonym="fbpC2"
                     /gene_synonym="mpt45"
     CDS             complement(156576..157598)
                     /gene="fbpC"
                     /locus_tag="Y980_0129c"
                     /gene_synonym="85C"
                     /gene_synonym="fbpC2"
                     /gene_synonym="mpt45"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0129c, (MT0137, MTCI5.03c) FbpC (alternate gene
                     names: mpt45, 85C, fbpC2), secreted antigen 85c
                     (fibronectin-binding protein C) (mycolyl transferase 85C)
                     (see citations below), also highly similar to other
                     Mycobacterial antigen precursors e.g. A85C_MYCLE|Q05862
                     antigen 85-c precursor (85c) from Mycobacterium leprae
                     (333 aa); etc."
                     /codon_start=1
                     /transl_table=11
                     /product="Secreted antigen 85-C FbpC (85C) (antigen 85
                     complex C) (AG58C) (mycolyl transferase 85C)
                     (fibronectin-binding protein C)"
                     /protein_id="AJF01475.1"
                     /db_xref="GOA:P0A4V4"
                     /db_xref="InterPro:IPR000801"
                     /db_xref="PDB:1DQY"
                     /db_xref="PDB:1DQZ"
                     /db_xref="PDB:1VA5"
                     /db_xref="PDB:3HRH"
                     /db_xref="UniProtKB/Swiss-Prot:P0A4V4"
                     /translation="MTFFEQVRRLRSAATTLPRRLAIAAMGAVLVYGLVGTFGGPATA
                     GAFSRPGLPVEYLQVPSASMGRDIKVQFQGGGPHAVYLLDGLRAQDDYNGWDINTPAF
                     EEYYQSGLSVIMPVGGQSSFYTDWYQPSQSNGQNYTYKWETFLTREMPAWLQANKGVS
                     PTGNAAVGLSMSGGSALILAAYYPQQFPYAASLSGFLNPSEGWWPTLIGLAMNDSGGY
                     NANSMWGPSSDPAWKRNDPMVQIPRLVANNTRIWVYCGNGTPSDLGGDNIPAKFLEGL
                     TLRTNQTFRDTYAADGGRNGVFNFPPNGTHSWPYWNEQLVAMKADIQHVLNGATPPAA
                     PAAPAA"
     gene            157845..158300
                     /gene="htdZ"
                     /locus_tag="Y980_0130"
     CDS             157845..158300
                     /gene="htdZ"
                     /locus_tag="Y980_0130"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0130, (MTCI5.04) Probable
                     htdZ,3-hydroxyl-thioester dehydratase. Forms single
                     hot-dog fold, features R-specific hydratase motif,
                     substrate unknown, forms homodimer. Shows structural
                     similarity to six others in Mycobacterium tuberculosis
                     (see Castell et al (2005) below). Similar to others e.g.
                     AL096811|SCI30A_19 from Streptomyces coelicolor (153 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 3-hydroxyl-thioester dehydratase"
                     /protein_id="AJF01476.1"
                     /db_xref="GOA:P96807"
                     /db_xref="InterPro:IPR002539"
                     /db_xref="PDB:2C2I"
                     /db_xref="UniProtKB/Swiss-Prot:P96807"
                     /translation="MRTFESVADLAAAAGEKVGQSDWVTITQEEVNLFADATGDHQWI
                     HVDPERAAAGPFGTTIAHGFMTLALLPRLQHQMYTVKGVKLAINYGLNKVRFPAPVPV
                     GSRVRATSSLVGVEDLGNGTVQATVSTTVEVEGSAKPACVAESIVRYVA"
     gene            complement(158313..159656)
                     /gene="fadE1"
                     /locus_tag="Y980_0131c"
     CDS             complement(158313..159656)
                     /gene="fadE1"
                     /locus_tag="Y980_0131c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0131c, (MTCI5.05c) Probable fadE1,acyl-CoA
                     dehydrogenase, similar to many e.g. ACDS_HUMAN|P16219
                     acyl-CoA dehydrogenase short-chain specific precursor (412
                     aa). Also highly similar to MTCI5_28 from Mycobacterium
                     tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA dehydrogenase FadE1"
                     /protein_id="AJF01477.1"
                     /db_xref="GOA:L7N5Y8"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR006092"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="UniProtKB/TrEMBL:L7N5Y8"
                     /translation="MPVRRRAGERLPTVWDFETDPQYQSKLDWVEKFMAEELEPLDLV
                     ALDPYDKKNADTMAILRPLQRQVKDQGLWAAHLRPELGGQGFGQVKLALLNEIIGRSR
                     WAPSAFGCQAPDSGNAEILALFGTDEQKARYLRPLLDGEITSCYSMTEPQGGSDPGLF
                     VTAATRDAAGNGDWIINGEKWFSTNAKHASFFIVMAVTKPEARTYEKMSLFIVPADTP
                     GIEIVRNVGVGAESTRHASHGYIRYHDVRVPADHVLGGEGQAFMIAQTRLGGGRIHHA
                     MRTIALARRAFDMMCERALSRQTRHGRLADLQMTQEKIADSWIQIEQFRLLVLRTAWL
                     IDKHHDYQKVRRDIAAVKVAMPQVLHDVVQRAMHLHGALGVSDEMPFVKMMLAAESLG
                     IADGATELHKMTVARRTLREYQPVTTLFPSQHIPTRRAHAEAWLAQRLEHAIAEF"
     gene            complement(159698..160780)
                     /gene="fgd2"
                     /locus_tag="Y980_0132c"
     CDS             complement(159698..160780)
                     /gene="fgd2"
                     /locus_tag="Y980_0132c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00013"
                     /note="Rv0132c, (MTCI5.06c) Putative fgd2,F420-dependent
                     glucose-6-phosphate dehydrogenase, highly similar to many
                     from Mycobacteria e.g. AAD38167|g5031431 from
                     Mycobacterium chelonae. Also similar to MJ1534|Q58929
                     N5,N10-methylene tetrahydromethanopterin reductase from
                     methanococcus jannaschii (342 aa). And also similar to
                     Rv0953c, Rv0791c, etc from Mycobacterium tuberculosis.
                     Contains PS00013 Prokaryotic membrane lipoprotein lipid
                     attachment site."
                     /codon_start=1
                     /transl_table=11
                     /product="Putative F420-dependent glucose-6-phosphate
                     dehydrogenase Fgd2"
                     /protein_id="AJF01478.1"
                     /db_xref="GOA:L0T5M8"
                     /db_xref="InterPro:IPR011251"
                     /db_xref="InterPro:IPR019945"
                     /db_xref="UniProtKB/TrEMBL:L0T5M8"
                     /translation="MTGISRRTFGLAAGFGAIGAGGLGGGCSTRSGPTPTPEPASRGV
                     GVVLSHEQFRTDRLVAHAQAAEQAGFRYVWASDHLQPWQDNEGHSMFPWLTLALVGNS
                     TSSILFGTGVTCPIYRYHPATVAQAFASLAILNPGRVFLGLGTGERLNEQAATDTFGN
                     YRERHDRLIEAIVLIRQLWSGERISFTGHYFRTDELKLYDTPAMPPPIFVAASGPQSA
                     TLAGRYGDGWIAQARDINDAKLLAAFAAGAQAAGRDPTTLGKRAELFAVVGDDKAAAR
                     AADLWRFTAGAVDQPNPVEIQRAAESNPIEKVLANWAVGTDPGVHIGAVQAVLDAGAV
                     PFLHFPQDDPITAIDFYRTNVLPELR"
     gene            160867..161472
                     /locus_tag="Y980_0133"
     CDS             160867..161472
                     /locus_tag="Y980_0133"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0133, (MTCI5.07) Probable acetyltransferase.
                     Contains GNAT (Gcn5-related N-acetyltransferase) domain in
                     C-terminal part. See Vetting et al. 2005. Highly similar
                     to others e.g. PUAC_STRLP|P13249 puromycyn
                     N-acetyltransferase (199 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="GCN5-related N-acetyltransferase"
                     /protein_id="AJF01479.1"
                     /db_xref="GOA:L7N608"
                     /db_xref="InterPro:IPR000182"
                     /db_xref="InterPro:IPR016181"
                     /db_xref="UniProtKB/TrEMBL:L7N608"
                     /translation="MTPQARPARRADVRELSRTMARAFYDDPVMSWLLSNDNARTARL
                     TRLFATIVRHQHLAGGGVEVARGAAGIGGAALWDPPDRWRESRRQQLAMTPGFLRVFG
                     FRTAKARAALDVMMRVHPEEPHWYLAAIGSDPTVRGQGFGQVLMRSRLDRCDAEHCPA
                     YLESTKPENVPYYQRFGFRVTREIALPDAGPPLWAMWREPR"
     gene            161769..162671
                     /gene="ephF"
                     /locus_tag="Y980_0134"
     CDS             161769..162671
                     /gene="ephF"
                     /locus_tag="Y980_0134"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0134, (MTCI5.08) Possible ephE,epoxide hydrolase
                     (see citation below), similar to others e.g. Q39856
                     epoxide hydrolase (341 aa). Also similar to MTCY09F9.26c
                     from Mycobacterium tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="putative epoxide hydrolase EphF (epoxide
                     hydratase) (arene-oxide hydratase)"
                     /protein_id="AJF01480.1"
                     /db_xref="GOA:L7N5E1"
                     /db_xref="InterPro:IPR000639"
                     /db_xref="UniProtKB/TrEMBL:L7N5E1"
                     /translation="MIALPALEGVEHRHVDVAEGVRIHVADAGPADGPAVMLVHGFPQ
                     NWWEWRDLIGPLAADGNRVLCPDLRGAGWSSAPRSRYTKTEMADDLAAVLDGLGVAKV
                     KLVAHDWGGPVAFIMMLRHPEKVTGFFGVNTVAPWVKRDLGMLRNMWRFWYQIPMSLP
                     VIGPRVISDPKGRYFRLLTGWVGGGFRVPDDDVRLYLDCMREPGHAEAGSRWYRTFQT
                     REMLRWLRGEYNDARVDVPVRWLHGTGDPVITPDLLDGYAERASDFEVELVDGVGHWI
                     VEQRPELVLDRVRAFLAAGTEQRD"
     gene            complement(162642..163247)
                     /locus_tag="Y980_0135c"
     CDS             complement(162642..163247)
                     /locus_tag="Y980_0135c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0135c, (MTCI5.09c) Possible transcriptional
                     regulator, weakly similar to others e.g. P32398|YHGD_BACSU
                     hypothetical transcriptional regulator from Bacillus
                     subtilis (191 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein"
                     /protein_id="AJF01481.1"
                     /db_xref="GOA:L7N632"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:L7N632"
                     /translation="MTAVAAGALVVETDSFRLRLLDGLVASIGERGYRATTVSDIVRH
                     ARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRAAVDPNADWHDQIRQAVEAYVTH
                     IESRPAVTLSWIREFPSLGAAAYPVQRRGMEQLTSLLIELSASPGFRRANLPPLNVPL
                     AVILLGGLRELTALTVEDGQPIRNIVEPAVDASIALLGPRS"
     gene            163364..164689
                     /gene="cyp138"
                     /locus_tag="Y980_0136"
     CDS             163364..164689
                     /gene="cyp138"
                     /locus_tag="Y980_0136"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00017"
                     /inference="protein motif:PROSITE:PS00086"
                     /note="Rv0136, (MT0144, MTCI5.10) Probable cyp138,
                     cytochrome P450 138, similar to others e.g. SLR0574|Q59990
                     from synechocystis SP. (444 aa); etc. Also similar to
                     MTV039_6 from Mycobacterium tuberculosis (472 aa).
                     Contains PS00017 ATP/GTP-binding site motif A (P-loop);
                     and PS00086 Cytochrome P450 cysteine heme-iron ligand
                     signature. Belongs to the cytochrome P450 family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cytochrome P450 138 Cyp138"
                     /protein_id="AJF01482.1"
                     /db_xref="GOA:P63717"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002401"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="UniProtKB/Swiss-Prot:P63717"
                     /translation="MSEVVTAAPAPPVVRLPPAVRGPKLFQGLAFVVSRRRLLGRFVR
                     RYGKAFTANILMYGRVVVVADPQLARQVFTSSPEELGNIQPNLSRMFGSGSVFALDGD
                     DHRRRRRLLAPPFHGKSMKNYETIIEEETLRETANWPQGQAFATLPSMMHITLNAILR
                     AIFGAGGSELDELRRLIPPWVTLGSRLAALPKPKRDYGRLSPWGRLAEWRRQYDTVID
                     KLIEAERADPNFADRTDVLALMLRSTYDDGSIMSRKDIGDELLTLLAAGHETTAATLG
                     WAFERLSRHPDVLAALVEEVDNGGHELRQAAILEVQRARTVIDFAARRVNPPVYQLGE
                     WVIPRGYSIIINIAQIHGDPDVFPQPDRFDPQRYIGSKPSPFAWIPFGGGTRRCVGAA
                     FANMEMDVVLRTVLRHFTLETTTAAGERSHGRGVAFTPKDGGRVVMRRR"
     gene            complement(164710..165258)
                     /gene="msrA"
                     /locus_tag="Y980_0137c"
     CDS             complement(164710..165258)
                     /gene="msrA"
                     /locus_tag="Y980_0137c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0137c, (MTCI5.11c) Probable msrA,peptide
                     methionine sulfoxide reductase (See St. John et al.,
                     2001), equivalent to CAC32179.1|AL583926 putative peptide
                     methionine sulfoxide from Mycobacterium leprae (177 aa).
                     Highly similar to others e.g. CAC18703.1|AL451182 putative
                     peptide methionine sulfoxide reductase from Streptomyces
                     coelicolor (172 aa); PMSR_SCHPO|Q09859 putative peptide
                     methionine sulfoxide reductase from Streptomyces (187 aa);
                     etc. Belongs to the MsrA family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative peptide methionine sulfoxide reductase
                     MsrA (protein-methionine-S-oxide reductase) (peptide
                     met(O) reductase)"
                     /protein_id="AJF01483.1"
                     /db_xref="GOA:P0A5L0"
                     /db_xref="InterPro:IPR002569"
                     /db_xref="PDB:1NWA"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5L0"
                     /translation="MTSNQKAILAGGCFWGLQDLIRNQPGVVSTRVGYSGGNIPNATY
                     RNHGTHAEAVEIIFDPTVTDYRTLLEFFFQIHDPTTKDRQGNDRGTSYRSAIFYFDEQ
                     QKRIALDTIADVEASGLWPGKVVTEVSPAGDFWEAEPEHQDYLQRYPNGYTCHFVRPG
                     WRLPRRTAESALRASLSPELGT"
     gene            165321..165824
                     /locus_tag="Y980_0138"
     CDS             165321..165824
                     /locus_tag="Y980_0138"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0138, (MTCI5.12) Conserved hypothetical protein,
                     showing weak similarity to Q10827|YT10_MYCTU hypothetical
                     17.0 KDA protein from Mycobacterium tuberculosis (147
                     aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01484.1"
                     /db_xref="InterPro:IPR009959"
                     /db_xref="UniProtKB/TrEMBL:L7N5M4"
                     /translation="MSASEFSRAELAAAFEKFEKTVARAAATRDWDCWVQHYTPDVEY
                     IEHAAGIMRGRQRVRAWIQETMTTFPGSHMVAFPSLWSVIDESTGRIICELDNPMLDP
                     GDGSVISATNISIITYAGNGQWCRQEDIYNPLRFLRAAMKWCRKAQELGTLDEDAARW
                     MRRHGGP"
     gene            165825..166847
                     /locus_tag="Y980_0139"
     CDS             165825..166847
                     /locus_tag="Y980_0139"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0139, (MTCI5.13) Possible oxidoreductase, similar
                     to others e.g. O34285|HPNA HPNA protein from Zymomonas
                     mobilis (337 aa); TRE_STRGR|P29782 dtdp-glucose
                     4,6-dehydratase (328 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01485.1"
                     /db_xref="GOA:L7N5K2"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:L7N5K2"
                     /translation="MNAPKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTR
                     SIDDLPLTRFHGDVFDTATVAEAMAGCDDVYYCVVDTRAWLRDPSPLFRTNVAGLRNV
                     LDVATDASLRRFVFTSSYATVGRRRGHVATEEDRVDTRKVTPYVRSRVAAEDLVLQYA
                     HDAGLPAVAMCVSTTYGGGDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARA
                     LILAAERGRNGERYLISERMMPLQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLR
                     ARLTGKDTELSLASVRMMRSEADVDHGKAVRELGWQPRPVEESIREAARFWAAMRTVG
                     KDPAAS"
     gene            166908..167288
                     /locus_tag="Y980_0140"
     CDS             166908..167288
                     /locus_tag="Y980_0140"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0140, (MTCI5.14) Conserved protein,similar to
                     others e.g. P74567|D90916_48 hypothetical 20.8 KDP protein
                     from Synechocystis sp. (180 aa). Also similar to Rv1056
                     and Rv1670 from Mycobacterium tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01486.1"
                     /db_xref="InterPro:IPR007361"
                     /db_xref="UniProtKB/TrEMBL:L7N4Y6"
                     /translation="MSNRIVLEPSADHPITIEPTNRRVQVRVNGEVVADTAAALCLQE
                     ASYPAVQYIPLADVVQDRLIRTETSTYCPFKGEASYYSVTTDAGDIVDDVMWTYENPY
                     PAVAAIAGHVACYPDKAEISIFPG"
     gene            complement(167269..167679)
                     /locus_tag="Y980_0141c"
     CDS             complement(167269..167679)
                     /locus_tag="Y980_0141c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0141c, (MTCI5.15c) Unknown protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01487.1"
                     /db_xref="InterPro:IPR009959"
                     /db_xref="UniProtKB/TrEMBL:L7N4G6"
                     /translation="MTPFDDPQAELAWMFLQSLCEGGDLDEGFALLSNDFTYWSIVTR
                     TELDKKTFRRAVERRKQVFEVNIELIRCVNEGETVVVEGHCDGVSADRTRYDSPFVCI
                     FETRDGMIISLREYSDTQSLAEVYPVACATPGRC"
     gene            167709..168635
                     /locus_tag="Y980_0142"
     CDS             167709..168635
                     /locus_tag="Y980_0142"
                     /note="Rv0142, (MTCI5.16) Conserved hypothetical protein,
                     similar, except in N-terminus, to AB88922.1|AL353862
                     hypothetical protein SCE34.20 from Streptomyces coelicolor
                     (326 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01488.1"
                     /db_xref="GOA:L7N508"
                     /db_xref="InterPro:IPR011257"
                     /db_xref="UniProtKB/TrEMBL:L7N508"
                     /translation="MRSIDVVVEAVVTFAGAAGFAHTLAPLRRGQQDPCFRVPGDGTI
                     WRTSLLPTGPVTARISRAGRDAARCVAWGSGAEEFVDMAPAMLGAADDASDFVPLHPA
                     VAAAHRRLPNLRLGRTGQVLEALIPAVIEQRVPGADAFRSWRLLVSKYGTQAPGPAPP
                     GMRVPPSAEVWRHIPSWEFHRANVDPGRARAVVGCAQRAASLERLVSLPAARAAEALT
                     SLPGVGVWTAAETTQRVFGDADAVSVGDYHIPKMIGWTLVGRPVDDAGMLELLEPMRP
                     HRHRVVRLLEASGLAREPRRGPRLPVQNIRAL"
     gene            complement(168702..170180)
                     /locus_tag="Y980_0143c"
     CDS             complement(168702..170180)
                     /locus_tag="Y980_0143c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0143c, (MTCI5.17c) Probable conserved
                     transmembrane protein, CIC family possibly involved in
                     transport of chloride, similar to others and hypothetical
                     proteins e.g. O28857 putative chloride channel from
                     Archaeoglobus fulgidus (589 aa); YADQ_ECOLI|P37019
                     hypothetical 46.0 kDa protein (436 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01489.1"
                     /db_xref="GOA:L0T4H6"
                     /db_xref="InterPro:IPR001807"
                     /db_xref="InterPro:IPR014743"
                     /db_xref="UniProtKB/TrEMBL:L0T4H6"
                     /translation="MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRFGVSIRSAGYL
                     RKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFAR
                     PWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASA
                     LTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLG
                     GAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPL
                     LWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILS
                     SGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVG
                     AAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGA
                     IIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRPTTA"
     gene            170282..171124
                     /locus_tag="Y980_0144"
     CDS             170282..171124
                     /locus_tag="Y980_0144"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0144, (MTCI5.18) Probable transcriptional
                     regulator, possibly TetR family. Has region similar to
                     others e.g. Q59431|UIDR_ECOLI|GUSR|B1618|Z2623|ECS2326 UID
                     operon repressor (GUS operon) from Escherichia coli
                     strains K12 and O157:H7 (196 aa). Contains probable
                     helix-turn helix motif from aa 109-130 (Score 1463, +4.17
                     SD). Could belong to the TetR/AcrR family of
                     transcriptional regulators."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein
                     (possibly TetR-family)"
                     /protein_id="AJF01490.1"
                     /db_xref="GOA:L7N5S4"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:L7N5S4"
                     /translation="MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGA
                     KLTSSVASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQVFS
                     ERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVAGIERARREPT
                     LMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELSRTENDAVRATREFLVWAV
                     NDAIERGELAADVDVSSLAETLLVVLCGVGFYIGFVGSYQRMATITDSFQQLLAGTLW
                     RPPT"
     gene            171213..172166
                     /locus_tag="Y980_0145"
     CDS             171213..172166
                     /locus_tag="Y980_0145"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0145, (MTCI5.19) Possible
                     S-adenosylmethionine-dependent methyltransferase (see
                     Grana et al., 2007), highly similar to many e.g.
                     CAC32172.1|AL583926 conserved hypothetical protein from
                     Mycobacterium leprae (310 aa); and several Mycobacterium
                     tuberculosis proteins e.g. Rv0726c, Rv0731c, etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative S-adenosylmethionine-dependent
                     methyltransferase"
                     /protein_id="AJF01491.1"
                     /db_xref="GOA:P96822"
                     /db_xref="InterPro:IPR007213"
                     /db_xref="InterPro:IPR011610"
                     /db_xref="UniProtKB/Swiss-Prot:P96822"
                     /translation="MTELDDVSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAA
                     TNPLIRDEFAKVLVSSAGTAWARLADADLAWLDGDQLGRRVHRVACDYQAVRTHFFDE
                     YFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQPSVLEYKAGILQSHGAVP
                     TARRHAVAVDLRDDWPAALIAAGFDGTQPTAWLAEGLLPYLPGDAADRLFDMVTALSA
                     PGSQVAVEAFTMNTKGNTQRWNRMRERLGLDIDVQALTYHEPDRSDAAQWLATHGWQV
                     HSVSNREEMARLGRAIPQDLVDETVRTTLLRGRLVTPAQPA"
     gene            172209..173141
                     /locus_tag="Y980_0146"
     CDS             172209..173141
                     /locus_tag="Y980_0146"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0146, (MTCI5.20) Possible
                     S-adenosylmethionine-dependent methyltransferase (see
                     Grana et al., 2007), highly similar to others e.g.
                     AC30975.1|AL583924 conserved hypothetical protein from
                     Mycobacterium leprae (304 aa); and several Mycobacterium
                     tuberculosis proteins e.g. Rv0726c, Rv0731c, etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative S-adenosylmethionine-dependent
                     methyltransferase"
                     /protein_id="AJF01492.1"
                     /db_xref="GOA:P96823"
                     /db_xref="InterPro:IPR007213"
                     /db_xref="InterPro:IPR011610"
                     /db_xref="UniProtKB/Swiss-Prot:P96823"
                     /translation="MRTHDDTWDIKTSVGATAVMVAAARAVETDRPDPLIRDPYARLL
                     VTNAGAGAIWEAMLDPTLVAKAAAIDAETAAIVAYLRSYQAVRTNFFDTYFASAVAAG
                     IRQVVILASGLDSRAYRLDWPAGTIVYEIDQPKVLSYKSTTLAENGVTPSAGRREVPA
                     DLRQDWPAALRDAGFDPTARTAWLAEGLLMYLPAEAQDRLFTQVGAVSVAGSRIAAET
                     APVHGEERRAEMRARFKKVADVLGIEQTIDVQELVYHDQDRASVADWLTDHGWRARSQ
                     RAPDEMRRVGRWVEGVPMADDPTAFAEFVTAERL"
     gene            173236..174756
                     /locus_tag="Y980_0147"
     CDS             173236..174756
                     /locus_tag="Y980_0147"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00070"
                     /inference="protein motif:PROSITE:PS00687"
                     /note="Rv0147, (MTCI5.21) Probable aldehyde dehydrogenase
                     (NAD+) dependent, similar to others e.g. DHAP_RAT|P11883
                     aldehyde dehydrogenase (dimeric NADP-preferring) (452 aa).
                     Also similar to several Mycobacterium tuberculosis
                     aldehyde dehydrogenases e.g. Rv0768, Rv2858c, etc.
                     Contains PS00687 aldehyde dehydrogenases glutamic acid
                     active site, and PS00070 aldehyde dehydrogenases cysteine
                     active site. Belongs to the aldehyde dehydrogenases
                     family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aldehyde dehydrogenase (NAD+)
                     dependent"
                     /protein_id="AJF01493.1"
                     /db_xref="GOA:L0T5P6"
                     /db_xref="InterPro:IPR012394"
                     /db_xref="InterPro:IPR015590"
                     /db_xref="InterPro:IPR016160"
                     /db_xref="InterPro:IPR016161"
                     /db_xref="InterPro:IPR016162"
                     /db_xref="InterPro:IPR016163"
                     /db_xref="UniProtKB/TrEMBL:L0T5P6"
                     /translation="MSDRVKAVAPPDGRTMMTTESVARKTQKSETEAPREPAPVSDEK
                     QTDVAKTVARLRKTFASGRTRSVEWRKQQLRALQKLMDENEDAIAAALAEDLDRNPFE
                     AYLADIATTSAEAKYAAKRVRRWMRRRYLLLEVPQLPGRGWVEYEPYGTVLIIGAWNY
                     PFYLTLGPAVGAIAAGNAVVLKPSEIAAASAHLMTELVYRYLDTEAIAVVQGDGAVSQ
                     ELIAQGFDRVMFTGGTEIGRKVYEGAAPHLTPVTLELGGKSPVIVAADADVDVAAKRI
                     AWIKLLNAGQTCVAPDYVLADATVRDELVSKITAALTKFRSGAPQGMRIVNQRQFDRL
                     SGYLAAAKTDAAADGGGVVVGGDCDASNLRIQPTVVVDPDPDGPLMSNEIFGPILPVV
                     TVKSLDDAIRFVNSRPKPLSAYLFTKSRAVRERVIREVPAGGMMVNHLAFQVSTAKLP
                     FGGVGASGMGAYHGRWGFEEFSHRKSVLTKPTRPDLSSFIYPPYTERAIKVARRLF"
     gene            174831..175691
                     /locus_tag="Y980_0148"
     CDS             174831..175691
                     /locus_tag="Y980_0148"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00061"
                     /note="Rv0148, (MTCI5.22) Probable short-chain
                     dehydrogenase, similar to others, in particular Estradiol
                     17 beta-dehydrogenases, e.g. DHB4_MOUSE|P51660 estradiol
                     17 beta-dehydrogenase 4 (735 aa). Contains PS00061
                     Short-chain alcohol dehydrogenase family signature.
                     Belongs to the short-chain dehydrogenases/reductases (SDR)
                     family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative short-chain type
                     dehydrogenase/reductase"
                     /protein_id="AJF01494.1"
                     /db_xref="GOA:P96825"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="UniProtKB/Swiss-Prot:P96825"
                     /translation="MPGVQDRVIVVTGAGGGLGREYALTLAGEGASVVVNDLGGARDG
                     TGAGSAMADEVVAEIRDKGGRAVANYDSVATEDGAANIIKTALDEFGAVHGVVSNAGI
                     LRDGTFHKMSFENWDAVLKVHLYGGYHVLRAAWPHFREQSYGRVVVATSTSGLFGNFG
                     QTNYGAAKLGLVGLINTLALEGAKYNIHANALAPIAATRMTQDILPPEVLEKLTPEFV
                     APVVAYLCTEECADNASVYVVGGGKVQRVALFGNDGANFDKPPSVQDVAARWAEITDL
                     SGAKIAGFKL"
     gene            175698..176666
                     /locus_tag="Y980_0149"
     CDS             175698..176666
                     /locus_tag="Y980_0149"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS01162"
                     /note="Rv0149, (MTCI5.23) Possible quinone oxidoreductase,
                     similar to others oxidoreductases e.g. Q08257 quinone
                     oxidoreductase (329 aa); SCHCOADH_4 from Streptomyces
                     coelicolor. Also similar to many proteins from
                     Mycobacterium tuberculosis. Contains PS01162 Quinone
                     oxidoreductase / zeta-crystallin signature. Belongs to the
                     zinc-containing alcohol dehydrogenase family, quinone
                     oxidoreductase subfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="putative quinone oxidoreductase (NADPH:quinone
                     oxidoreductase) (zeta-crystallin)"
                     /protein_id="AJF01495.1"
                     /db_xref="GOA:L7N539"
                     /db_xref="InterPro:IPR002085"
                     /db_xref="InterPro:IPR002364"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:L7N539"
                     /translation="MKACVVKELSGPSGMVYTDIDEVSGDGGKVVIDVRAAGVCFPDL
                     LLTKGEYQLKLTPPFVPGMETAGVVRSAPSDAGFHVGERVSAFGVLGGYAEQIAVPVA
                     NVVRSPVELDDAGAVSLLVNYNTMYFALARRAALRPGDTVLVLGAAGGVGTAAVQIAK
                     AMQAGKVIAMVHREGAIDYVASLGADVVLPLTEGWAQQVRDHTYGQGVDIVVDPIGGP
                     TFDDALGVLAIDGKLLLIGFAAGAVPTLKVNRLLVRNISVVGVGWGEYLNAVPGSAAL
                     FAWGLNQLVFLGLRPPPPQRYPLSEAQAALQSLDDGGVLGKVVLEP"
     gene            complement(176663..176950)
                     /locus_tag="Y980_0150c"
     CDS             complement(176663..176950)
                     /locus_tag="Y980_0150c"
                     /note="Rv0150c, (MTCI5.24c) Conserved hypothetical
                     protein, showing some similarity with C-terminus of
                     O53949|Rv1800|MTV049.22 PPE-family protein from
                     Mycobacterium tuberculosis (655 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01496.1"
                     /db_xref="UniProtKB/TrEMBL:L7N5X9"
                     /translation="MLTLPDDRAPTGLPDPGIEALAHTKIASTISTVVADGYAVVLST
                     ADIANSLLANAIGYPIAASVALVTPAAGANSSCWPADPSQHHRIAESRACA"
     gene            complement(177541..179307)
                     /gene="PE1"
                     /locus_tag="Y980_0151c"
     CDS             complement(177541..179307)
                     /gene="PE1"
                     /locus_tag="Y980_0151c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0151c, (MTCI5.25c) PE1, Member of the
                     Mycobacterium tuberculosis PE family (see citation below),
                     with N-terminal region similar to others e.g. MTV032_2
                     PE_PGRS family from Mycobacterium tuberculosis (468 aa);
                     MTCY493_24 from Mycobacterium tuberculosis. Also similar
                     to upstream ORF MTCI5.26c. Also shows similarity to
                     C-terminal part of some PPE family proteins e.g. MTV049_21
                     from Mycobacterium tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="PE family protein PE1"
                     /protein_id="AJF01497.1"
                     /db_xref="InterPro:IPR000084"
                     /db_xref="InterPro:IPR013228"
                     /db_xref="UniProtKB/TrEMBL:L0T5V5"
                     /translation="MAPFGFTPKARHNRGVALRSTYRLDGWVMGPVDKEGWGLSYVFA
                     QPSVLAAAATDLAGIGSAINQATAAVAAPTTGLAAAAADEVSTALATLFGAYGQQFQA
                     ISAQVAAFHNEFTQRLAAAANAFVNAEATNTSALVQEATAGLFKPTSPPVLPPMFNQN
                     TAIIMGGTGSPIPTPSYVNAITTLFIDPVVSNPVVKALVTPEELYPITGVKSLPFQTS
                     VQLGLQILDGAIWEQINAGNHVTVFGYSQSAVIASLEMQHLISLGPNAPSPSQLNFIL
                     IGNEMNPNGGILARIPGLNVTTLGLPFYGATPDNPYPTTTYTLEYDGFADFPRYPLNV
                     LSDINAVFGILTVHTTYADLTPAQIASATQLPTQGTTSNTYYIIETEHLPLLAPLRAI
                     PVIGPPLAALVEPNLEVIVNLGYGDPRFGYSTSPANVPTPFGLFPDVPASVVADALVA
                     GTQQGVNDFMVELPAALNTLPQTPMPAFPPYVPTLLPPPPPPQPATLINIADTFASVV
                     STGYSILLPTADLGLAFVTILPAYDLTLFVNQLAAGNLRAAIELPLAATIGLAALGGM
                     IEFIAIVVTLADITQQLQSFSI"
     gene            complement(179317..180894)
                     /gene="PE2"
                     /locus_tag="Y980_0152c"
     CDS             complement(179317..180894)
                     /gene="PE2"
                     /locus_tag="Y980_0152c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0152c, (MTCI5.26c) PE2, Member of the
                     Mycobacterium tuberculosis PE family (see citation below),
                     similar to ORF downstream Z92770|MTCI5_25 (588 aa); and to
                     many other PE family type members. Predicted to be an
                     outer membrane protein (See Song et al.,2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="PE family protein PE2"
                     /protein_id="AJF01498.1"
                     /db_xref="InterPro:IPR013228"
                     /db_xref="UniProtKB/TrEMBL:L0T5Q1"
                     /translation="MRCRPPSRNRSAHTARNTRPCSLKSRRFTVRFHQTLAAAANSYA
                     DAEAAIASTRQNQLAVPAAAPTPAAAAMIPPFPANLTTLFFGPTGIPLPPPSMLTPPI
                     RCRSVRRALQAVFTPEELYPLTGVRSLVLNTSVEEGLTILHDAIMVELATTGNAVTVF
                     GWSQSAIIASLEMQRFTAMGGAAPSASDLNFVLVGNEMNPNGGMLARFPDLTLPTLDL
                     TFYGATPSDTIYPTAIYTLEYDGFADFSRYPLNFISDLNAVAGITFVHTKYLDLTPAQ
                     VEGATKLPTSPGYTGVTDYYIIRTENRPLLQPLRAVPVIGDPLADLIQPNLKVIVNLG
                     YGDPNYGYSTSYADVRTPFGLWPNVPPQVIADALAAGTQEGILDFTADLQALSAQPLT
                     LPQIQLPQPADLVAAVAAAPTPAEVVNTLARIISTNYAVLLPTVDIALALVTTLPLYT
                     TQLFVRQLAAGNLINAIGYPLAATVGLGTIDSGRRGIAHPPRGGLGHRSKHRGPRHLT
                     DSRRHRRPPTTVYRPRQ"
     gene            complement(181153..181983)
                     /gene="ptbB"
                     /locus_tag="Y980_0153c"
                     /gene_synonym="MPtpB"
     CDS             complement(181153..181983)
                     /gene="ptbB"
                     /locus_tag="Y980_0153c"
                     /gene_synonym="MPtpB"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0153c, (MTCI5.27c) PtbB (alternate gene name:
                     MPtpB), protein-tyrosine-phosphatase (see citation below),
                     showing some similarity to several protein-tyrosine
                     phosphatases, polyketide synthase and aminotransferase
                     e.g. Q05918|IPHP_NOSCO|IPH protein-tyrosine-phosphatase
                     precursor from Nostoc commune (294 aa); etc. Supposedly a
                     secreted protein. Potent and selective inhibitor is an
                     isoxazole compound (See Seollner et al., 2007)."
                     /codon_start=1
                     /transl_table=11
                     /product="Phosphotyrosine protein phosphatase PTPB
                     (protein-tyrosine-phosphatase) (PTPase)"
                     /protein_id="AJF01499.1"
                     /db_xref="GOA:P96830"
                     /db_xref="InterPro:IPR000387"
                     /db_xref="InterPro:IPR025163"
                     /db_xref="InterPro:IPR026893"
                     /db_xref="PDB:1YWF"
                     /db_xref="PDB:2OZ5"
                     /db_xref="UniProtKB/TrEMBL:P96830"
                     /translation="MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATL
                     RRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLL
                     TNDGSNGESGESSQSINDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHC
                     FAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPE
                     VVTFTKARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
                     "
     gene            complement(181985..183196)
                     /gene="fadE2"
                     /locus_tag="Y980_0154c"
     CDS             complement(181985..183196)
                     /gene="fadE2"
                     /locus_tag="Y980_0154c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0154c, (MTCI5.28c) Probable fadE2,acyl-CoA
                     dehydrogenase, similar to many e.g. C-terminal region of
                     O01590 acyl-CoA dehydrogenase (974 aa); ACDS_MEGEL|Q06319
                     acyl-CoA dehydrogenase (short-chain) (383 aa). Could
                     belong to the acyl-CoA dehydrogenases family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA dehydrogenase FadE2"
                     /protein_id="AJF01500.1"
                     /db_xref="GOA:L0T2P6"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR006092"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="UniProtKB/TrEMBL:L0T2P6"
                     /translation="MSAKAIDYRTRLSDFMTEHVFGAEADYDDYRRAAGPADHTAPPI
                     IEELKTKAKDRGLWNLFLSAESGLTNLEYAPLAEMTGWSMEIAPEALNCAAPDTGNME
                     ILHMFGTEQQRAQWLRPLLDGKIRSAFSMTEPAVASSDARNIETTISRDGADYVINGR
                     KWWTSGAADPRCKILIVMGRTNPDAAAHQQQSMVLVPIDTPGVTIVRSTPVFGWQDRH
                     GHCEIDYHNVRVPATNLLGEEGSGFAIAQARLGPGRIHHCMRALGAAERALALMVNRV
                     RNRVAFGRPLAEQGVVQQAIAQSRNEIDQARLLCEKAAWTIDQHGNKEARHLVAMIKA
                     VAPRVACDVIDRAIQVHGAAGVSDDTPLARLYGWHRAMRIFDGPDEVHLRSIARAELS
                     REKSTFAAAVT"
     gene            183620..184720
                     /gene="pntAa"
                     /locus_tag="Y980_0155"
     CDS             183620..184720
                     /gene="pntAa"
                     /locus_tag="Y980_0155"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0155, (MTCI5.29) Probable pntAa,first part of
                     NAD(P) transhydrogenase subunit alpha,similar to
                     N-terminus of others e.g. PNTA_ECOLI|P07001|P76888|B1603
                     NAD (P) transhydrogenase subunit alpha from Escherichia
                     coli strain K12 (510 aa); proton-translocating
                     nicotinamide nucleotide transhydrogenase subunit PNTAA."
                     /codon_start=1
                     /transl_table=11
                     /product="putative NAD(P) transhydrogenase (subunit alpha)
                     PntAa [first part; catalytic part] (pyridine nucleotide
                     transhydrogenase subunit alpha) (nicotinamide nucleotide
                     transhydrogenase subunit alpha)"
                     /protein_id="AJF01501.1"
                     /db_xref="GOA:L0T2U7"
                     /db_xref="InterPro:IPR007698"
                     /db_xref="InterPro:IPR007886"
                     /db_xref="InterPro:IPR026255"
                     /db_xref="UniProtKB/TrEMBL:L0T2U7"
                     /translation="MTDPQTQSTRVGVVAESGPDERRVALVPKAVASLVNRGVAVVVE
                     AGAGERALLPDELYTAVGASIGDAWAADVVVKVAPPTAAEVGRLRGGQTLIGFLAPRN
                     ADNSIGALTQAGVQAFALEAIPRISRAQVMDALSSQANVSGYKAVLLAASESTRFFPM
                     LTTAAGTVKPATVLVLGVGVAGLQALATAKRLGARTTGYDVRPEVADQVRSVGAQWLD
                     LGISASGEGGYARELTDDERAQQQKALEEAISGFDVVITTALVPGRPAPTLVTAAAVE
                     AMKPGSVVVDLAGETGGNCELTEPGRTVVKHDVTIAAPLNLPATMPEHASELYSKNIT
                     ALLDLLIKDGRLAPDFDDEVIAQSCVTRGKDS"
     gene            184721..185053
                     /gene="pntAb"
                     /locus_tag="Y980_0156"
     CDS             184721..185053
                     /gene="pntAb"
                     /locus_tag="Y980_0156"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0156, (MTCI5.30) Probable pntAb,second part of
                     NAD(P) transhydrogenase subunit alpha,integral membrane
                     protein, similar to C-terminus of others e.g. Q59764
                     nicotinamide nucleotide transhydrogenase subunit PNTAB
                     (139 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative NAD(P) transhydrogenase (subunit alpha)
                     PntAb [second part; integral membrane protein] (pyridine
                     nucleotide transhydrogenase subunit alpha) (nicotinamide
                     nucleotide transhydrogenase subunit alpha)"
                     /protein_id="AJF01502.1"
                     /db_xref="InterPro:IPR024605"
                     /db_xref="UniProtKB/TrEMBL:L0T5W1"
                     /translation="MYNELLENLAILVLSGFVGFAVISKVPNTLHTPLMSGTNAIHGI
                     VVLGALVVFGEIEHPSLVLQVILFVAVVFGTLNVIGGFIVTDRMLGMFKAKKPAVPAK
                     PDRDEALR"
     gene            185050..186477
                     /gene="pntB"
                     /locus_tag="Y980_0157"
     CDS             185050..186477
                     /gene="pntB"
                     /locus_tag="Y980_0157"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0157, (MTCI5.31) Probable pntB,pyridine
                     nucleotide transhydrogenase (nicotinamide nucleotide
                     transhydrogenase) subunit beta, integral membrane protein,
                     similar to others e.g. Q59763 proton-translocating
                     nicotinamide nucleotide transhydrogenase subunit beta from
                     hodospirillum rubrum (464 aa);
                     07002|PNTB_ECOLI|P76890|PNTB|B1602|Z2597|ECS2308 NAD(P)
                     transhydrogenase subunit beta from Escherichia coli
                     strains K12 and O157:H7 (462 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative NAD(P) transhydrogenase (subunit beta)
                     PntB [integral membrane protein] (pyridine nucleotide
                     transhydrogenase subunit beta) (nicotinamide nucleotide
                     transhydrogenase subunit beta)"
                     /protein_id="AJF01503.1"
                     /db_xref="GOA:L7N505"
                     /db_xref="InterPro:IPR012136"
                     /db_xref="UniProtKB/TrEMBL:L7N505"
                     /translation="MNLHYLVEILYIISFSLFIYGLMGLTGPKTAVRGNLIAAAGMTI
                     AVAATLVMIRHTSQWPLIIAGLVVGVVLGVPPARLTKMTAMPQLVAFFNGVGGGTVAL
                     IALSEFIDTTGFSAFQHGESPTVHIVVASLFAAIIGSISFWGSIVAFGKLQEIISGRP
                     IGLGKAQQPINLLLLAVAVAAAVVIGLHAHPGSGGVALWWMIGLLVAAGVLGLMVVLP
                     IGGADMPVVISMLNAMTGLSAAAAGLALNNTAMIVAGMIVGASGSILTNLMAKAMNRS
                     IPAIVAGGFGGGGVAPSGGGDDKHVKATSAADAAIQMAYANQVIVVPGYGLAVAQAQH
                     AVKDLATLLEDRGVPVKYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDMDDINDEFART
                     DVTIVIGANDVTNPAARNETSSPIYGMPILNVDKSRSVIVLKRSMNSGFAGIDNPLFY
                     ADGTTMLFGDAKKSVTEVSEELKAL"
     gene            complement(186493..186621)
                     /locus_tag="Y980_0157A"
     CDS             complement(186493..186621)
                     /locus_tag="Y980_0157A"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0157A Conserved protein, showing similarity to
                     C-terminal part (aa 186-220) of O53976|Rv1975|MTV051.13
                     conserved hypothetical protein from Mycobacterium
                     tuberculosis (221 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01504.1"
                     /db_xref="UniProtKB/TrEMBL:L0T4J1"
                     /translation="MMDPSPDYDVSDEIEFFFRYLTWGLRGVETGDGYPPPAYPPV"
     gene            186783..187427
                     /locus_tag="Y980_0158"
     CDS             186783..187427
                     /locus_tag="Y980_0158"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0158, (MTV032.01) Probable transcriptional
                     regulator, possibly TetR family, showing weak similarity
                     to various transcriptional activators and repressors e.g.
                     P32398|YIXD_BACSU|YHGD hypothetical transcriptional
                     regulatory protein from Bacillus subtilis (191 aa).
                     Contains helix-turn-helix motif at aa 32-53 (Score 1296,
                     +3.60 SD). Could belong to the TetR/AcrR family of
                     transcriptional regulators."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein
                     (possibly TetR-family)"
                     /protein_id="AJF01505.1"
                     /db_xref="GOA:L7N4U0"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR013571"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:L7N4U0"
                     /translation="MPSDTSPNGLSRREELLAVATKLFAARGYHGTRMDDVADVIGLN
                     KATVYHYYASKSLILFDIYRQAAEGTLAAVHDDPSWTAREALYQYTVRLLTAIASNPE
                     RAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVAL
                     GYIGMTLGSYRWLRPSGRRTAKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET"
     gene            complement(187431..188837)
                     /gene="PE3"
                     /locus_tag="Y980_0159c"
     CDS             complement(187431..188837)
                     /gene="PE3"
                     /locus_tag="Y980_0159c"
                     /note="Rv0159c, (MTV032.02c) PE3, Member of the
                     Mycobacterium tuberculosis PE family (see citation below),
                     similar to many other PE proteins e.g. O06828 from
                     Mycobacterium tuberculosis (528 aa). Also highly similar
                     to upstream MTV032_3, and to MTCI5_25,MTCI5_26, MTV049_
                     21, MTCY1A10_26, etc."
                     /codon_start=1
                     /transl_table=11
                     /product="PE family protein PE3"
                     /protein_id="AJF01506.1"
                     /db_xref="InterPro:IPR000084"
                     /db_xref="InterPro:IPR013228"
                     /db_xref="UniProtKB/TrEMBL:L0T2V2"
                     /translation="MSYVIAAPEMLATTAADVDGIGSAIRAASASAAGPTTGLLAAAA
                     DEVSSAAAALFSEYARECQEVLKQAAAFHGEFTRALAAAGAAYAQAEASNTAAMSGTA
                     GSSGALGSVGMLSGNPLTALMMGGTGEPILSDRVLAIIDSAYIRPIFGPNNPVAQYTP
                     EQWWPFIGNLSLDQSIAQGVTLLNNGINAELQNGHDVVVFGYSQSAAVATNEIRALMA
                     LPPGQAPDPSRLAFTLIGNINNPNGGVLERYVGLYLPFLDMSFNGATPPDSPYQTYMY
                     TGQYDGYAHNPQYPLNILSDLNAFMGIRWVHNAYPFTAAEVANAVPLPTSPGYTGNTH
                     YYMFLTQDLPLLQPIRAIPFVGTPIAELIQPDLRVLVDLGYGYGYADVPTPASLFAPI
                     NPIAVASALATGTVQGPQAALVSIGLLPQSALPNTYPYLPSANPGLMFNFGQSSVTEL
                     SVLSGALGSVARLIPPIA"
     gene            complement(188929..190437)
                     /gene="PE4"
                     /locus_tag="Y980_0160c"
     CDS             complement(188929..190437)
                     /gene="PE4"
                     /locus_tag="Y980_0160c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0160c, (MTV032.03c) PE4, Member of the
                     Mycobacterium tuberculosis PE family (see citation below),
                     similar to many other PE proteins e.g. Z92770|MTCI5_26c
                     from Mycobacterium tuberculosis (525 aa); C-terminal
                     region of O06801|RV1768|MTCY28.34 from Mycobacterium
                     tuberculosis (618 aa). Also highly similar to downstream
                     ORF MTV032_2."
                     /codon_start=1
                     /transl_table=11
                     /product="PE family protein PE4"
                     /protein_id="AJF01507.1"
                     /db_xref="InterPro:IPR000084"
                     /db_xref="InterPro:IPR013228"
                     /db_xref="UniProtKB/TrEMBL:Q7DAC9"
                     /translation="MSHLVTAPDMLATAAAHVDEIASTLRAANAAAAGPTCNLLAAAG
                     DEVSAATAALFSAYGREYQAVVKQAAAFHSEFTRTLEAAGNAYAHAEAANAARVSHAL
                     DTINAPIRTLLGRAPLSPNGSSGAGGLPAIAQLAAESPITALIMGGTNNPLPDPEYVT
                     DINKAFIQTLFPGAVSQGLFTPEQFWPVTPDLGNLTFNQSVTEGVALLNTAVNNQLAL
                     DNKVVAFGYSQSATIINNYINSLMAMGSPNPDDISFVMIGSGNNPVGGLLARFPGFYI
                     PFLDVPFNGATPANSPYPTHIYTAQYDGIAHAPQFPLRILSDINAFMGYFYVHNTYPE
                     LMATQVDNAVPLPTSPGYTGNTQYYMFLTQDLPLLQPIRDIPYAGPPIADLFQPQLRV
                     LVDLGYADYGPGGNYADIPTPAGLFSIPNPFAVTYYLIKGSLQAPYGAIVEIGVEAGL
                     IGPEWFPDSYPWVPSINPGLNFYFGQPQVTLLSLMSGGLGNILHLIPPPVFT"
     gene            190605..191954
                     /locus_tag="Y980_0161"
     CDS             190605..191954
                     /locus_tag="Y980_0161"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0161, (MTCI28.01, MTV032.04) Possible
                     oxidoreductase, similar to hypothetical proteins and
                     various oxidoreductases e.g. AIP2_YEAST|P46681 actin
                     interacting protein 2 (530 aa); DLD1_YEAST|P32891
                     d-lactate dehydrogenase (cytochrome) (587 aa). Also
                     similar to other Mycobacteria proteins e.g. MTCY339.30c
                     from Mycobacterium tuberculosis; MLCL622.30c from
                     Mycobacterium tuberculosis (449 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01508.1"
                     /db_xref="GOA:L0T5Q7"
                     /db_xref="InterPro:IPR004113"
                     /db_xref="InterPro:IPR006094"
                     /db_xref="InterPro:IPR016164"
                     /db_xref="InterPro:IPR016166"
                     /db_xref="InterPro:IPR016167"
                     /db_xref="InterPro:IPR016169"
                     /db_xref="InterPro:IPR016171"
                     /db_xref="UniProtKB/TrEMBL:L0T5Q7"
                     /translation="MLTSLVSAVGSHHVTTDPDVLAGRSVDHTGRYRGRASALVRPGS
                     AEEVAEVLRVCRDAGAYVTVQGGRTSLVAGTVPEHDDVLLSTERLCVVSDVDTVERRI
                     EIGAGVTLAAVQHAASTAGLVFGVDLSARDTATVGGMASTNAGGLRTVRYGNMGEQVV
                     GLDVALPDGTVLRRHSRVRRDNTGYDLPALFVGAEGTLGVITALDLRLHPTPSHRVTA
                     VCGFAELAALVDAGRMFRDVEGIAALELIDGRAAALTREHLGVRPPVEADWLLLVELA
                     ADHDQTDRLADLLGGARMCGEPAVGVDAAAQQRLWRTRESLAEVLGVYGPPLKFDVSL
                     PLSAISGFARDAVALVHRHVPDSPEALPLLFGHIGEGNLHLNVLRCPPDREPALYAKM
                     MGLIAECGGNVSSEHGVGSRKRAYLGMSRQANDVAAMRRVKAALDPTGYLNAAVLFD"
     gene            complement(191982..193133)
                     /gene="adhE1"
                     /locus_tag="Y980_0162c"
     CDS             complement(191982..193133)
                     /gene="adhE1"
                     /locus_tag="Y980_0162c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00059"
                     /note="Rv0162c, (MTCI28.02c) Probable adhE1,zinc-type
                     alcohol dehydrogenase, similar to others e.g.
                     ADH_MACMU|P28469 alcohol dehydrogenase alpha chain (374
                     aa). Also similar to other alcohol dehydrogenases from
                     Mycobacterium tuberculosis e.g. MTCY369.06c, MTV022_9.
                     Contains PS00059 Zinc-containing alcohol dehydrogenases
                     signature. Belongs to the zinc-containing alcohol
                     dehydrogenase family,class-I subfamily. Cofactor: zinc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc-type alcohol dehydrogenase (E
                     subunit) AdhE1"
                     /protein_id="AJF01509.1"
                     /db_xref="GOA:Q7DAC8"
                     /db_xref="HSSP:P00327"
                     /db_xref="InterPro:IPR002085"
                     /db_xref="InterPro:IPR002328"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q7DAC8"
                     /translation="MPAVQPWLYSNMPAIRGAVLDQIGVPRPYWRSKPISVVELHLDP
                     PDRGEVLVRIEAAGVCHSDLSVVDGTRVRPVPILLGHEAAGIVEQVGDGVDGVAVGQR
                     VVLVFLPRCGQCAACATDGRTPCEPGSAANKAGTLLGGGIRLSRGGRPVYHHLGVSGF
                     ATHVVVNRASVVPVPHEVPPTVAALLGCAVLTGGGAVLNVGDPQPGQSVAVVGLGGVG
                     MAAVLTALTYTDVRVVAVDQLPEKLSAAKALGAHEIYTPQQATAGGVKAAVVVEAVGH
                     PAALHTAIGLTAPGGRTITVGLPPPDVRISLSPLDFVTEGRSLIGSYLGSAVPSHDIP
                     RFVSLWQSGRLPVESLVTSTIRLDDINEAMDHLADGIAVRQLISFTGDL"
     gene            193115..193570
                     /locus_tag="Y980_0163"
     CDS             193115..193570
                     /locus_tag="Y980_0163"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0163, (MTCI28.03) Conserved protein,similar to
                     others e.g. Q44017 hypothetical 16.6 KDA protein in GBD
                     5'region (ORF6)from Alcaligenes eutrophus (145 aa). Also
                     weak similarity with MTV008.31c|Rv2475c|B70867 from
                     Mycobacterium tuberculosis (138 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01510.1"
                     /db_xref="InterPro:IPR006683"
                     /db_xref="UniProtKB/TrEMBL:L0T2Q5"
                     /translation="MAALPAPEKLLRSDFPVLWPVGTRWADNDMFGHLNNAVYYQLFD
                     TAINAWINTSTGVDPLAMPVLGIVAESGCRYFSELRFPESLMVGLAVTRLGRSSVTYR
                     LGVFKEPDDAGVITALGHWVHVYVDRTSRRPVPIPEAIRSLLSTACVSG"
     gene            193624..194109
                     /gene="TB18.5"
                     /locus_tag="Y980_0164"
     CDS             193624..194109
                     /gene="TB18.5"
                     /locus_tag="Y980_0164"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0164, (MTCI28.04) TB18.5, conserved protein,
                     equivalent to CAB08818.1|Z95398 hypothetical protein from
                     Mycobacterium leprae (156 aa). Some similarity to Rv2185c,
                     Rv0854, Rv0857 from Mycobacterium tuberculosis.
                     Alternative start codon has been suggested. 3' part
                     corrected since first submission (-24 aa). A core
                     mycobacterial gene; conserved in mycobacterial strains
                     (See Marmiesse et al., 2004). Predicted to be an outer
                     membrane protein (See Song et al., 2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="Conserved protein TB18.5"
                     /protein_id="AJF01511.1"
                     /db_xref="GOA:Q8VKQ8"
                     /db_xref="InterPro:IPR005031"
                     /db_xref="InterPro:IPR023393"
                     /db_xref="UniProtKB/TrEMBL:Q8VKQ8"
                     /translation="MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPE
                     WNEGVKGAWVLARYDDGRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGELFA
                     KQEQLFSVVATGAASLLTVDMDVQVTMPVPEPMVKMLLNNVLEHLAENLKQRAEQLAA
                     S"
     gene            complement(194142..194813)
                     /gene="mce1R"
                     /locus_tag="Y980_0165c"
     CDS             complement(194142..194813)
                     /gene="mce1R"
                     /locus_tag="Y980_0165c"
                     /note="Rv0165c, (MTCI28.05c) Probable
                     mce1R,transcriptional regulator, GntR family (See Casali
                     et al.,2006), showing some similarity to several e.g.
                     NTRA_CHELE|P54988 nta operon transcriptional regulator
                     (231 aa); P46833|GNTR_BACLI gluconate operon
                     transcriptional repressor from Bacillus licheniformis (243
                     aa); GNTR_BACSU gluconate operon repressor from Bacillus
                     subtilis (243 aa). Also similar to Rv0043c from
                     Mycobacterium tuberculosis. Seems to belong to the GntR
                     family of transcriptional regulators. Start changed since
                     first submission (-41 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein
                     Mce1R (probably GntR-family)"
                     /protein_id="AJF01512.1"
                     /db_xref="GOA:L0T5W8"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR027376"
                     /db_xref="UniProtKB/TrEMBL:L0T5W8"
                     /translation="MNAPLSAKPRSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIR
                     LDETAAELGVSVTPVREALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQ
                     ELATSATAHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKLA
                     WFLLNAARYMGAGVRGRPAMGRGRGEQSSAADRRAAPPRHSRRNRAHRLAVHRWGTQA
                     DGGPG"
     gene            194991..196655
                     /gene="fadD5"
                     /locus_tag="Y980_0166"
     CDS             194991..196655
                     /gene="fadD5"
                     /locus_tag="Y980_0166"
                     /inference="protein motif:PROSITE:PS00455"
                     /note="Rv0166, (MTCI28.06) Probable fadD5,fatty-acid-CoA
                     synthetase, similar to many eg LCFA_ECOLI|P29212
                     long-chain-fatty-acid--CoA ligase (561 aa). Also similar
                     to many other fatty-acid-CoA ligases from Mycobacterium
                     tuberculosis e.g. MTCY07A7.11c, MTV013_10,MTY25D10_30,
                     etc. Contains PS00455 putative AMP-binding domain
                     signature."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fatty-acid-CoA ligase FadD5
                     (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)"
                     /protein_id="AJF01513.1"
                     /db_xref="GOA:L0T5R1"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="UniProtKB/TrEMBL:L0T5R1"
                     /translation="MTAQLASHLTRALTLAQQQPYLARRQNWVNQLERHAMMQPDAPA
                     LRFVGNTMTWADLRRRVAALAGALSGRGVGFGDRVMILMLNRTEFVESVLAANMIGAI
                     AVPLNFRLTPTEIAVLVEDCVAHVMLTEAALAPVAIGVRNIQPLLSVIVVAGGSSQDS
                     VFGYEDLLNEAGDVHEPVDIPNDSPALIMYTSGTTGRPKGAVLTHANLTGQAMTALYT
                     SGANINSDVGFVGVPLFHIAGIGNMLTGLLLGLPTVIYPLGAFDPGQLLDVLEAEKVT
                     GIFLVPAQWQAVCTEQQARPRDLRLRVLSWGAAPAPDALLRQMSATFPETQILAAFGQ
                     TEMSPVTCMLLGEDAIAKRGSVGRVIPTVAARVVDQNMNDVPVGEVGEIVYRAPTLMS
                     CYWNNPEATAEAFAGGWFHSGDLVRMDSDGYVWVVDRKKDMIISGGENIYCAELENVL
                     ASHPDIAEVAVIGRADEKWGEVPIAVAAVTNDDLRIEDLGEFLTDRLARYKHPKALEI
                     VDALPRNPAGKVLKTELRLRYGACVNVERRSASAGFTERRENRQKL"
     gene            196859..197656
                     /gene="yrbE1A"
                     /locus_tag="Y980_0167"
     CDS             196859..197656
                     /gene="yrbE1A"
                     /locus_tag="Y980_0167"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0167, (MTCI28.07) YrbE1A, unknown integral
                     membrane protein, part of mce1 operon and member of YrbE
                     family (see citations below), highly similar to
                     Mycobacterium tuberculosis proteins
                     O07791|Rv0587|MTCY19H5.35|yrbE2A (265 aa);
                     O53965|Rv1964|MTV051.02|yrbE3A (265 aa); etc. Also highly
                     similar or similar to conserved hypothetical integral
                     membrane proteins of yrbEA type, e.g.
                     NP_302654.1|NC_002677 conserved membrane protein from
                     Mycobacterium leprae (267 aa); P45030|YRBE_HAEIN|HI1086
                     hypothetical protein from Haemophilus influenzae (261 aa);
                     etc."
                     /codon_start=1
                     /transl_table=11
                     /product="Conserved integral membrane protein YrbE1A"
                     /protein_id="AJF01514.1"
                     /db_xref="InterPro:IPR003453"
                     /db_xref="UniProtKB/TrEMBL:L7N5B8"
                     /translation="MTTSTTLGGYVRDQLQTPLTLVGGFFRMCVLTGKALFRWPFQWR
                     EFILQCWFIMRVGFLPTIMVSIPLTVLLIFTLNILLAQFGAADISGSGAAIGAVTQLG
                     PLTTVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVLASMLVATLL
                     NGLVITVGLVGGFLFGVYLQNVSGGAYLATLTLITGLPEVVIATIKAATFGLIAGLVG
                     CYRGLTVRGGSKGLGTAVNETVVLCVIALFAVNVILTTIGVRFGTGR"
     gene            197658..198527
                     /gene="yrbE1B"
                     /locus_tag="Y980_0168"
     CDS             197658..198527
                     /gene="yrbE1B"
                     /locus_tag="Y980_0168"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0168, (MTCI28.08) YrbE1B, unknown integral
                     membrane protein, part of mce1 operon and member of YrbE
                     family (see citations below), highly similar to
                     Mycobacterium tuberculosis proteins
                     O07790|Rv0588|MTCY19H5.34|yrbE2B (295 aa);
                     O53966|Rv1965|MTV051.03|yrbE3B (271 aa); etc. Also highly
                     similar to conserved hypothetical integral membrane
                     proteins of the yrbEB type, e.g. NP_302655.1|NC_002677
                     conserved membrane protein from Mycobacterium leprae (289
                     aa); P45030|YRBE_HAEIN|HI1086 hypothetical protein from
                     Haemophilus influenzae (261 aa); etc."
                     /codon_start=1
                     /transl_table=11
                     /product="Conserved integral membrane protein YrbE1B"
                     /protein_id="AJF01515.1"
                     /db_xref="InterPro:IPR003453"
                     /db_xref="UniProtKB/TrEMBL:L0T2Q9"
                     /translation="MSTAAVLRARFPRAVANLRQYGGAAARGLDEAGQLTWFALTSIG
                     QIAHALRYYRKETLRLIAQIGMGTGAMAVVGGTVAIVGFVTLSGSSLVAIQGFASLGN
                     IGVEAFTGFFAALINVRIAGPVVTGVALAATVGAGATAELGAMRISEEIDALEVMGIK
                     SISFLASTRIMAGLVVIIPLYALAMIMSFLSPQITTTVLYGQSNGTYEHYFQTFLRPD
                     DVFWSFLEALIITAIVMVSHCYYGYAAGGGPVGVGEAVGRSMRFSLVSVQVVVLFAAL
                     ALYGVDPNFNLTV"
     gene            198532..199896
                     /gene="mce1A"
                     /locus_tag="Y980_0169"
                     /gene_synonym="mce1"
     CDS             198532..199896
                     /gene="mce1A"
                     /locus_tag="Y980_0169"
                     /gene_synonym="mce1"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0169, (MTCI28.09) Mce1A; belongs to 24-membered
                     Mycobacterium tuberculosis Mce protein family (see
                     citations below), highly similar to Mycobacterium
                     tuberculosis proteins
                     O07789|MCE2|Rv0589|MTCY19H5.33c|mce2A (404 aa);
                     O53967|MCE3|Rv1966|MTV051.04|mce3A (425 aa); etc. Also
                     highly similar to others e.g.
                     AAD52105.1|AF113402_1|AF113402 mycobacterial cell entry
                     protein from Mycobacterium bovis BCG (454 aa);
                     NP_302656.1|NC_002677 putative cell invasion protein from
                     Mycobacterium leprae (441 aa); AAA92845.1|U26018 mce gene
                     product from Mycobacterium avium (88 aa) (similarity on
                     C-terminus); CAC12798.1|AL445327 putative secreted protein
                     from Streptomyces coelicolor (418 aa); etc. Note that
                     equivalent, but longer 22 aa, to P72013|CAA50257.1|X70901
                     Mcep protein from Mycobacterium tuberculosis (432 aa).
                     Contains a very hydrophobic region around residues 20-35.
                     Note that previously known as mce1. A core mycobacterial
                     gene; conserved in mycobacterial strains (See Marmiesse et
                     al., 2004). Predicted to be an outer membrane protein (See
                     Song et al., 2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="Mce-family protein Mce1A"
                     /protein_id="AJF01516.1"
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="InterPro:IPR024516"
                     /db_xref="UniProtKB/TrEMBL:F5BH89"
                     /translation="MTTPGKLNKARVPPYKTAGLGLVLVFALVVALVYLQFRGEFTPK
                     TQLTMLSARAGLVMDPGSKVTYNGVEIGRVDTISEVTRDGESAAKFILDVDPRYIHLI
                     PANVNADIKATTVFGGKYVSLTTPKNPTKRRITPKDVIDVRSVTTEINTLFQTLTSIA
                     EKVDPVKLNLTLSAAAEALTGLGDKFGESIVNANTVLDDLNSRMPQSRHDIQQLAALG
                     DVYADAAPDLFDFLDSSVTTARTINAQQAELDSALLAAAGFGNTTADVFDRGGPYLQR
                     GVADLVPTATLLDTYSPELFCTIRNFYDADPLAKAASGGGNGYSLRTNSEILSGIGIS
                     LLSPLALATNGAAIGIGLVAGLIAPPLAVAANLAGALPGIVGGAPNPYTYPENLPRVN
                     ARGGPGGAPGCWQPITRDLWPAPYLVMDTGASLAPYNHMEVGSPYAVEYVWGRQVGDN
                     TINP"
     gene            199893..200933
                     /gene="mce1B"
                     /locus_tag="Y980_0170"
                     /gene_synonym="mceD"
     CDS             199893..200933
                     /gene="mce1B"
                     /locus_tag="Y980_0170"
                     /gene_synonym="mceD"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0170, (MTCI28.10) Mce1B (alternate gene name:
                     mceD); belongs to 24-membered Mycobacterium tuberculosis
                     Mce protein family (see citations below),highly similar to
                     Mycobacterium tuberculosis proteins
                     O07788|Rv0590|MTCY19H5.32c|mce2B (275 aa);
                     O53968|Rv1967|MTV051.05|mce3B (342 aa); etc. Also highly
                     similar to others e.g. NP_302657.1|NC_002677 putative
                     secreted protein from Mycobacterium leprae (346 aa);
                     CAC12797.1|AL445327 putative secreted protein from
                     Streptomyces coelicolor (354 aa); etc. Contains
                     hydrophobic region in N-terminal 30 residues. In
                     Escherichia coli,N-terminal part is functional and directs
                     export of a leaderless beta-lactamase into the periplasm
                     (see Chubb et al., 1998). Predicted to be an outer
                     membrane protein (See Song et al., 2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="Mce-family protein Mce1B"
                     /protein_id="AJF01517.1"
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="InterPro:IPR024516"
                     /db_xref="UniProtKB/TrEMBL:L7N4C4"
                     /translation="MKITGTVVKLGIVSVVLLFFTVMIIVIFGQMRFDRTNGYTAEFS
                     NVSGLRQGQFVRASGVEIGKVKALHLVDGGRRVRVEFNIDRSVPLYQSTTAQIRYSDL
                     IGNRYVELKRGEGKGANDLLPPGGLIPLSRTSPALDLDALIGGFKPVFRALDPAKVNN
                     IANALITVFQGQGGTINDILDQTAQLTSQIAERDQAIGEVVKNLNIVLDTTVKHRKEF
                     DETVNNLENLITGLRNHSDQLAGGLAHISNGAGTVADLLAENRTLVRKAVSYLDAIQQ
                     PVIDQRVELDDLLHKTPTALTALGRANGTYGDFQNFYLCDLQIKWNGFQAGGPVRTVK
                     LFSQPTGRCTPQ"
     gene            200930..202477
                     /gene="mce1C"
                     /locus_tag="Y980_0171"
     CDS             200930..202477
                     /gene="mce1C"
                     /locus_tag="Y980_0171"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0171, (MTCI28.11) Mce1C; belongs to 24-membered
                     Mycobacterium tuberculosis Mce protein family (see
                     citations below), highly similar to Mycobacterium
                     tuberculosis proteins O07787|Rv0591|MTCY19H5.31|mce2C (481
                     aa); O53969|Rv1968|MTV051.06|mce3C (410 aa); etc. Also
                     highly similar to others e.g. NP_302658.1|NC_002677
                     putative secreted protein from Mycobacterium leprae (519
                     aa); CAC12796.1|AL445327 putative secreted protein from
                     Streptomyces coelicolor (351 aa); etc. Weakly similar to
                     downstream ORF Rv0172|MTCI28.12|mce1D (530 aa). Contains
                     possible signal sequence and highly proline-rich
                     C-terminus. Predicted to be an outer membrane protein (See
                     Song et al., 2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="Mce-family protein Mce1C"
                     /protein_id="AJF01518.1"
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="InterPro:IPR008360"
                     /db_xref="UniProtKB/TrEMBL:F5BH93"
                     /translation="MRTLEPPNRMRIGLMGIVVALLVVAVGQSFTSVPMLFAKPSYYG
                     QFTDSGGLHKGDRVRIAGLGVGTVEGLKIDGDHIVVKFSIGTNTIGTESRLAIRTDTI
                     LGRKVLEIEPRGAQALPPGGVLPVGQSTTPYQIYDAFFDVTKAASGWDIETVKRSLNV
                     LSETVDQTYPHLSAALDGVAKFSDTIGKRDEQITHLLAQANQVASILGDRSEQVDRLL
                     VNAKTLIAAFNERGRAVDALLGNISAFSAQVQNLINDNPNLNHVLEQLRILTDLLVDR
                     KEDLAETLTILGRFSASFGETFASGPYFKVLLANLVPGQILQPFVDAAFKKRGISPED
                     FWRSAGLPAYRWPDPNGTRFPNGAPPPPPPVLEGTPEHPGPAVPPGSPCSYTPPADGL
                     PRPWDPLPCANLTQGPFGGPDFPAPLDVATSPPNPDGPPPAPGLPIAGRPGEVPPNVP
                     GTPVPIPQEAPPGARTLPLGPAPGPAPPPAAPGPPAPPGPGPQLPAPFINPGGTGGSG
                     VTGGSEN"
     gene            202474..204066
                     /gene="mce1D"
                     /locus_tag="Y980_0172"
     CDS             202474..204066
                     /gene="mce1D"
                     /locus_tag="Y980_0172"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0172, (MTCI28.12) Mce1D; belongs to 24-membered
                     Mycobacterium tuberculosis Mce protein family (see
                     citations below), highly similar to Mycobacterium
                     tuberculosis proteins O07786|Rv0592|MTCY19H5.30c|mce2D
                     (508 aa); O53970|Rv1969|MTV051.07|mce3D (423 aa); etc.
                     Also highly similar to others e.g. NP_302659.1|NC_002677
                     putative secreted protein from Mycobacterium leprae (531
                     aa); CAC12795.1|AL445327 putative secreted protein from
                     Streptomyces coelicolor (337 aa); etc. Hydrophobic region
                     at N-terminus. Predicted to be an outer membrane protein
                     (See Song et al., 2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="Mce-family protein Mce1D"
                     /protein_id="AJF01519.1"
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="UniProtKB/TrEMBL:L7N5G3"
                     /translation="MSTIFDIRNLRLPQLSRASVVIGSLVVVLALAAGIVGVRLYQKL
                     TNNTVVAYFTQANALYVGDKVQIMGLPVGSIDKIEPAGDKMKVTFHYQNKYKVPANAS
                     AVILNPTLVASRNIQLEPPYRGGPVLADNAVIPVERTQVPTEWDELRDSVSHIIDELG
                     PTPEQPKGPFGEVIEAFADGLAGKGKQINTTLNSLSQALNALNEGRGDFFAVVRSLAL
                     FVNALHQDDQQFVALNKNLAEFTDRLTHSDADLSNAIQQFDSLLAVARPFFAKNREVL
                     THDVNNLATVTTTLLQPDPLDGLETVLHIFPTLAANINQLYHPTHGGVVSLSAFTNFA
                     NPMEFICSSIQAGSRLGYQESAELCAQYLAPVLDAIKFNYFPFGLNVASTASTLPKEI
                     AYSEPRLQPPNGYKDTTVPGIWVPDTPLSHRNTQPGWVVAPGMQGVQVGPITQGLLTP
                     ESLAELMGGPDIAPPSSGLQTPPGPPNAYDEYPVLPPIGLQAPQVPIPPPPPGPDVIP
                     GPVPPTPAPVGAPLPAEAGGGQ"
     gene            204063..205235
                     /gene="lprK"
                     /locus_tag="Y980_0173"
                     /gene_synonym="mce1E"
     CDS             204063..205235
                     /gene="lprK"
                     /locus_tag="Y980_0173"
                     /gene_synonym="mce1E"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00013"
                     /note="Rv0173, (MTCI28.13) Possible lprK (alternate gene
                     name: mce1E), lipoprotein which belongs to 24-membered
                     Mycobacterium tuberculosis Mce protein family (see
                     citations below), highly similar to Mycobacterium
                     tuberculosis proteins O07785|LPRL|Rv0593|MTCY19H5.29|mce2E
                     (402 aa); O53971|LPRM|Rv1970|MTV051.08|mce3E (377 aa);
                     etc. Also highly similar to others e.g.
                     NP_302660.1|NC_002677 putative lipoprotein from
                     Mycobacterium leprae (392 aa); CAC12794.1|AL445327
                     putative secreted protein from Streptomyces coelicolor
                     (413 aa); etc. Contains PS00013 prokaryotic membrane
                     lipoprotein lipid attachment site."
                     /codon_start=1
                     /transl_table=11
                     /product="putative Mce-family lipoprotein LprK (Mce-family
                     lipoprotein Mce1E)"
                     /protein_id="AJF01520.1"
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="UniProtKB/TrEMBL:L0T2R3"
                     /translation="MMSVLARMRVMRHRAWQGLVLLVLALLLSSCGWRGISNVAIPGG
                     PGTGPGSYTIYVQMPDTLAINGNSRVMVADVWVGSIRAIKLKNWVATLTLSLKKDVTL
                     PKNATAKIGQTSLLGSQHVELAAPPDPSPVPLKDGDTIPLKRSSAYPTTEQTLASIAT
                     LLRGGGLVNLEGIQQEINAIVTGRADQIRAFLGKLDTFTDELNQQRDDITRAIDSTNR
                     LLAYVGGRSEVLNRVLTDLPPLIKHFADKQELLINASDAVGRLSQSADQYLSAARGDL
                     HQDLQALQCPLKELRRAAPYLVGALKLILTQPFDVDTVPQLVRGDYMNLSLTLDLTYS
                     AIDNAFLTGTGFSGALRALEQSFGRDPETMIPDIRYTPNPNDAPGGPLVERGNRQC"
     gene            205229..206776
                     /gene="mce1F"
                     /locus_tag="Y980_0174"
     CDS             205229..206776
                     /gene="mce1F"
                     /locus_tag="Y980_0174"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0174, (MTCI28.14) Mce1F; belongs to 24-membered
                     Mycobacterium tuberculosis Mce protein family (see
                     citations below), similar to Mycobacterium tuberculosis
                     proteins O07784|Rv0594|MTCY19H5.28c|mce2F (516 aa);
                     O53972|Rv1971|MTV051.09|mce3F (437 aa); etc. Also highly
                     similar to others e.g. NP_302661.1|NC_002677 putative
                     secreted protein from Mycobacterium leprae (516 aa);
                     AAF74993.1|AF143400_1|AF143400|996A027a protein from
                     Mycobacterium avium (80 aa) (similarity on C-terminus);
                     CAC12793.1|AL445327 putative secreted protein from
                     Streptomyces coelicolor (433 aa); etc. Has hydrophobic
                     stretch, possibly a signal peptide at the N-terminus.
                     Predicted to be an outer membrane protein (See Song et
                     al.,2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="Mce-family protein Mce1F"
                     /protein_id="AJF01521.1"
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="UniProtKB/TrEMBL:L0T2W6"
                     /translation="MLTRFIRRQLILFAIVSVVAIVVLGWYYLRIPSLVGIGQYTLKA
                     DLPASGGLYPTANVTYRGITIGKVTAVEPTDQGARVTMSIASNYKIPVDASANVHSVS
                     AVGEQYIDLVSTGAPGKYFSSGQTITKGTVPSEIGPALDNSNRGLAALPTEKIGLLLD
                     ETAQAVGGLGPALQRLVDSTQAIVGDFKTNIGDVNDIIENSGPILDSQVNTGDQIERW
                     ARKLNNLAAQTATRDQNVRSILSQAAPTADEVNAVFSGVRDSLPQTLANLEVVFDMLK
                     RYHAGVEQLLVFLPQGAAIAQTVLTPTPGAAQLPLAPAINYPPPCLTGFLPASEWRSP
                     ADTSPRPLPSGTYCKIPQDAQLQVRGARNIPCVDVLGKRAATPKECRSKDPYVPLGTN
                     PWFGDPNQILTCPAPGARCDQPVKPGLVIPAPSINTGLNPAPADQVQGTPPPVSDPLQ
                     RPGSGTVQCNGQQPNPCVYTPTSGPSAVYSPASGELVGPDGVKYAVANSSTTGDDGWK
                     EMLAPAS"
     repeat_region   206810..206848
                     /note="39 bp direct repeat
                     1,AGGTGAAGGCGGCGGATTCGGCGGAATCTGACGCCGGAG"
     gene            206812..207453
                     /locus_tag="Y980_0175"
     CDS             206812..207453
                     /locus_tag="Y980_0175"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0175, (MTCI28.15) Probable conserved
                     Mce-associated membrane protein, equivalent, but longer in
                     N-terminus, to CAC32127.1|AL583926 possible membrane
                     protein from Mycobacterium leprae (182 aa). Also similar
                     to mce-associated proteins from Mycobacterium tuberculosis
                     e.g. Rv1363c, Rv0177, Rv1973, etc. Contains two 12 residue
                     direct repeats at N-terminus. A core mycobacterial gene;
                     conserved in mycobacterial strains (See Marmiesse et
                     al.,2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved Mce associated membrane
                     protein"
                     /protein_id="AJF01522.1"
                     /db_xref="UniProtKB/TrEMBL:L0T5X4"
                     /translation="MKAADSAESDAGADQTGPQVKAADSAESDAGELGEDACPEQALV
                     ERRPSRLRRGWLVGIAATLLALAGGLGAAGYFALRSHQESQSIAREDLAAIEAAKDCV
                     AATQAPDAGAMSASMQKIIECGTGDFGAQASLYTSMLVEAYQAASVHVQVTDMRAAVE
                     RNNNDGSVDVLVALRVKVSNTDSDAHEVGYRLRVRMALDEGRYKIAKLDQVTK"
     repeat_region   206867..206905
                     /locus_tag="Y980_0175"
                     /note="39 bp direct repeat
                     2,AGGTGAAGGCGGCGGATTCGGCGGAATCTGACGCCGGAG"
     gene            207450..208418
                     /locus_tag="Y980_0176"
     CDS             207450..208418
                     /locus_tag="Y980_0176"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0176, (MTCI28.16) Probable conserved
                     Mce-associated transmembrane protein. Contains short
                     region of similarity to PRA_MYCLE|P41484 proline-rich
                     antigen (36 kDa antigen) from Mycobacterium leprae (249
                     aa) (outside the proline-rich region). Also similar to
                     mce-associated proteins from Mycobacterium tuberculosis
                     e.g. Rv1363c, Rv0177, Rv3493c, etc. A core mycobacterial
                     gene; conserved in mycobacterial strains (See Marmiesse et
                     al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved Mce associated transmembrane
                     protein"
                     /protein_id="AJF01523.1"
                     /db_xref="GOA:L0T5R6"
                     /db_xref="InterPro:IPR010432"
                     /db_xref="UniProtKB/TrEMBL:L0T5R6"
                     /translation="MTVVVEKTPTTLPQATPNGAAPWHVRAGAFAIDVLPGLAVAATM
                     ALTALTVPPGSAWRWLCACLLGLTILLLAVNRLLLPTITGWSLGRALTGIRVVRRDGS
                     AIGPWRLLVRDLAHLVDTLSLFVGWLWPLWDSRRRTFADLLLRTEVRRVEPVQRPAVI
                     RRLTAAVALAAAGACASATAVGAAVVYVNEWQTDHTRAQLATRGPKLVVDVLSYDPET
                     VQRDFERARSLATDRYRPQLSIQQDSVRESGPVRNQYWVTDSAVLSATPAQATMLLFM
                     QGERGTPPNQRYIQSTVRAIFQKSRGQWRLDDLAVVMKPRQPTGEK"
     gene            208415..208969
                     /locus_tag="Y980_0177"
     CDS             208415..208969
                     /locus_tag="Y980_0177"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0177, (MTCI28.17) Probable conserved
                     Mce-associated protein, equivalent to CAC32129.1|AL583926
                     conserved membrane protein from Mycobacterium leprae (184
                     aa). Also similar to mce-associated proteins from
                     Mycobacterium tuberculosis e.g. Rv1363c, Rv1973,
                     Rv3493c,etc. A core mycobacterial gene; conserved in
                     mycobacterial strains (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved Mce associated protein"
                     /protein_id="AJF01524.1"
                     /db_xref="UniProtKB/TrEMBL:L7N5H6"
                     /translation="MSPRRKFEPGEGALLAPQSIEPSRRWGLPLALTASAVVMAAAIS
                     ACALMRISHESHQRAAHKDIVMLSDVRSFMTMFTSPDPFHANEYAERVLSHATGDFAK
                     QYHERANDILIRISGVEPTTGTVLDAGVQRWNEDGSANVLVVTQITSKSADGKRVVSN
                     ANRWLVTAKQEGNEWKISSLLPVI"
     gene            208936..209670
                     /locus_tag="Y980_0178"
     CDS             208936..209670
                     /locus_tag="Y980_0178"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0178, (MTCI28.18) Probable conserved
                     Mce-associated membrane protein, highly similar in
                     C-terminus to CAC32130.1|AL583926 putative secreted
                     protein from Mycobacterium leprae (184 aa). Also similar
                     to mce-associated proteins from Mycobacterium tuberculosis
                     e.g. Rv1363c, Rv0177, Rv1973, etc. Note that there is a 10
                     aa overlap with the upstream ORF. A core mycobacterial
                     gene; conserved in mycobacterial strains (See Marmiesse et
                     al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved Mce associated membrane
                     protein"
                     /protein_id="AJF01525.1"
                     /db_xref="UniProtKB/TrEMBL:L7N5B1"
                     /translation="MEDQQSASGDLTQKSVANGESTDTASAATEGHRGEIDAAGEPDE
                     RGAAVADSQADEDDSAATAARGGKTRARRSRGRRLAITVGVAAALFVGSAAFAGATVE
                     PYLSERAVVATKLMVARTAANAITTLWTYTPENMDTLADRAANYLSGDFAAQYRRFVD
                     QIAAANKQAKITNDTEVTGAAVESLSGRDAVAIVYTNTTTTSPVTKNIPALKYLSYRL
                     FMKRYDARWLVTRMTTITSLDLTPQV"
     gene            complement(209701..210810)
                     /gene="lprO"
                     /locus_tag="Y980_0179c"
     CDS             complement(209701..210810)
                     /gene="lprO"
                     /locus_tag="Y980_0179c"
                     /inference="protein motif:PROSITE:PS00013"
                     /note="Rv0179c, (MTCI28.19c) Possible lprO,lipoprotein
                     (visibly not conserved). Contains possible N-terminal
                     signal sequence and PS00013 Prokaryotic membrane
                     lipoprotein lipid attachment site."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipoprotein LprO"
                     /protein_id="AJF01526.1"
                     /db_xref="InterPro:IPR018711"
                     /db_xref="UniProtKB/TrEMBL:L7N4T3"
                     /translation="MWIRAERVAVLTPTASLRRLTACYAALAVCAALACTTGQPAARA
                     ADGREMLAQAIATTRGSYLVYNFGGGHPMPLLNAGGHWYEMNNGGHLMIIKNASQRLS
                     PHLLVDTHTGDQARCEHNPGARTGEGLWQASEIYPPLKAWQRMGRPTIAVNANFFDVR
                     GQKGGSWRSTGCSSPLGAYVDNTRGQGRANQAVTGTVAYAGKQGLSGGNELWSSLTTM
                     ILPVGGAPYVLRPKSRQDYDLATPVIEDLLNKNARFVAVAGIGLLSPGNTGQLHDGGP
                     SAARTALAYAKQKDEMYIFQGGNYTPDNIQDLFRGLGSDTAILLDGGGSSAIVLRRDT
                     GGMWAGAGSPKGSCDTRQVLCDSHERALPSWLAFN"
     gene            complement(210890..212248)
                     /locus_tag="Y980_0180c"
     CDS             complement(210890..212248)
                     /locus_tag="Y980_0180c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0180c, (MTCI28.20c) Probable conserved
                     transmembrane protein, equivalent to CAC32132.1|AL583926
                     probable conserved membrane protein from Mycobacterium
                     leprae (465 aa). Shows some similarity with others
                     membrane proteins e.g. AL096849|SCI11_29 from Streptomyces
                     coelicolor (354 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01527.1"
                     /db_xref="GOA:L7N5G4"
                     /db_xref="InterPro:IPR022703"
                     /db_xref="UniProtKB/TrEMBL:L7N5G4"
                     /translation="MSQAQPRPAAPNPKRNVKAIRTVRFWMAPIATTLALMSALAALY
                     LGGILNPMTNLRHFPIALVNEDAGPAGQQIVDGLVSGLDKNKFDIRVVSPDEARRLLD
                     TAAVYGSALIPPTFSSQLRDFGASAVTPTRTDRPAITISTNPRAGTLAASIAGQTLTR
                     ALTVVNGKVGERLTAEVAAQTGGVALAGAAAAGLASPIDVKSTAYNPLPNGTGNGLSA
                     FYYALLLLLAGFTGSIVVSTLVDSMLGYVPAEFGPVYRFAEQVNISRFRTLLVKWAVM
                     VVLALLTSGVYLAIAHGLGMPIPLGWQVWLYGVFAIIAVGVTSSSLIAVLGSMGLLVS
                     MLIFVILGLPSAGATVPLEAVPAFFRWLAQFEPMHQVFLGVRSLLYLNGNADAGLSQA
                     LTMTSIGLIIGLLLGGFITHLYDRSSFHRIPGAVEMAIAVEHQAQYQARQSARESSSE
                     QP"
     gene            complement(212275..213009)
                     /locus_tag="Y980_0181c"
     CDS             complement(212275..213009)
                     /locus_tag="Y980_0181c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0181c, (MTCI28.21c) Conserved hypothetical
                     protein, highly similar to other hypothetical proteins
                     e.g. YHHW_ECOLI|P46852 hypothetical 26.3 kd protein from
                     Escherichia coli (231 aa); P73623|SLL1773 hypothetical
                     25.7 kDa protein from Synechocystis sp. strain PCC 6803
                     (232 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01528.1"
                     /db_xref="GOA:P65724"
                     /db_xref="InterPro:IPR003829"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR012093"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/Swiss-Prot:P65724"
                     /translation="MTATVEIRRAADRAVTTTSWLKSRHSFSFGDHYDPDNTHHGLLL
                     VNNDDQMEPASGFDPHPHRDMEIVTWVLRGALRHQDSAGNSGVIYPGLAQRMSAGTGI
                     LHSEMNDSATEPVHFVQMWVIPDATGITASYQQQEIDDELLRAGLVTIASGIPGQDAA
                     LTLHNSSASLHGARLRPGATVSLPCAPFLHLFVAYGRLTLEGGGELADGDAVRFTDAD
                     ARGLTANEPSEVLIWEMHAKLGDSAT"
     gene            complement(213026..214138)
                     /gene="sigG"
                     /locus_tag="Y980_0182c"
     CDS             complement(213026..214138)
                     /gene="sigG"
                     /locus_tag="Y980_0182c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS01063"
                     /note="Rv0182c, (MTCI28.22c), len: 370 aa (start site
                     uncertain; first of several possibles was chosen, but note
                     that this overlaps the upstream ORF). Probable
                     sigG,alternative RNA polymerase sigma subunit (see
                     citations below), similar to many e.g. Q45585|SIGW_BACSU
                     RNA polymerase sigma factor from Bacillus subtilis (187
                     aa). Also similar to nine other ECF sigma factors from
                     Mycobacterium tuberculosis e.g. Rv1221, Rv0735, etc.
                     Contains PS01063 Sigma-70 factors ECF subfamily signature
                     and probable helix-turn helix motif from aa 205-226 (Score
                     1181, +3.21 SD). Belongs to the sigma-70 factor family,
                     ECF subfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="putative alternative RNA polymerase sigma factor
                     SigG (RNA polymerase ECF type sigma factor)"
                     /protein_id="AJF01529.1"
                     /db_xref="GOA:L7N5U5"
                     /db_xref="InterPro:IPR000838"
                     /db_xref="InterPro:IPR007627"
                     /db_xref="InterPro:IPR009959"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR013249"
                     /db_xref="InterPro:IPR013324"
                     /db_xref="InterPro:IPR013325"
                     /db_xref="InterPro:IPR014284"
                     /db_xref="InterPro:IPR014305"
                     /db_xref="UniProtKB/TrEMBL:L7N5U5"
                     /translation="MRTSPMPAKFRSVRVVVITGSVTAAPVRVSETLRRLIDVSVLAE
                     NSGREPADERRGDFSAHTEPYRRELLAHCYRMTGSLHDAEDLVQETLLRAWKAYEGFA
                     GKSSLRTWLHRIATNTCLTALEGRRRRPLPTGLGRPSADPSGELVERREVSWLEPLPD
                     VTDDPADPSTIVGNRESVRLAFVAALQHLSPRQRAVLLLRDVLQWKSAEVADAIGTST
                     VAVNSLLQRARSQLQTVRPSAADRLSAPDSPEAQDLLARYIAAFEAYDIDRLVELFTA
                     EAIWEMPPYTGWYQGAQAIVTLIHQQCPAYSPGDMRLISLIANGQPAAAMYMRAGDVH
                     LPFQLHVLDMAADRVSHVVAFLDTTLFPKFGLPDSL"
     gene            214086..214925
                     /locus_tag="Y980_0183"
     CDS             214086..214925
                     /locus_tag="Y980_0183"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0183, (MTCI28.23) Possible lysophospholipase,
                     similar to several (especially eukaryotic enzymes, weaker
                     with Escherichia coli), e.g. U67963|HSU67963_1 Human
                     lysophospholipase homolog from Homo sapiens (313 aa);
                     P07000|PLDB_ECOLI lysophospholipase L2 from Escherichia
                     coli (165 aa). Start changed based on similarity to
                     AE001997_8 from Deinococcus radiodurans (282 aa). Also
                     shows some similarity to epoxide hydrolases from
                     Mycobacterium tuberculosis e.g. Rv1938 and
                     O07214|YR15_MYCTU|Rv2715|MT2788|MTCY05A6.36 (341 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lysophospholipase"
                     /protein_id="AJF01530.1"
                     /db_xref="InterPro:IPR000073"
                     /db_xref="UniProtKB/TrEMBL:L0T2S2"
                     /translation="MTTTRTERNFAGIGDVRIVYDVWTPDTAPQAVVVLAHGLGEHAR
                     RYDHVAQRLGAAGLVTYALDHRGHGRSGGKRVLVRDISEYTADFDTLVGIATREYPGC
                     KRIVLGHSMGGGIVFAYGVERPDNYDLMVLSAPAVAAQDLVSPVVAVAAKLLGVVVPG
                     LPVQELDFTAISRDPEVVQAYNTDPLVHHGRVPAGIGRALLQVGETMPRRAPALTAPL
                     LVLHGTDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFNEPERNQVLDDVVAWLT
                     ERL"
     gene            214967..215716
                     /locus_tag="Y980_0184"
     CDS             214967..215716
                     /locus_tag="Y980_0184"
                     /note="Rv0184, (MTCI28.24) Conserved hypothetical protein,
                     equivalent to CAC32136.1|AL583926 conserved hypothetical
                     protein from Mycobacterium leprae (249 aa); and C-terminus
                     highly similar to CAB08793.1|Z95398 conserved hypothetical
                     protein from Mycobacterium leprae (145 aa). Also similar
                     to 049841|SCE9_39|T36358 hypothetical protein from
                     Streptomyces coelicolor (418 aa). A core mycobacterial
                     gene; conserved in mycobacterial strains (See Marmiesse et
                     al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01531.1"
                     /db_xref="InterPro:IPR024498"
                     /db_xref="UniProtKB/TrEMBL:L7N562"
                     /translation="MTNDKMLARIAALLRQAEGTDNPHEADAFMSTAQRLATAASIDL
                     AVARSHAGNRSPAQAPTQRTITIGAAGTRGLRTYVQLFVLIAAANDVRCDVASNSTFV
                     YAYGFAEDIDTSHALYASLVVQMVRASDAYLASGAHRPTPTITARLNFQLAFGARVGQ
                     RLADAREQTRQEATKDRDRPPGTAIALRDKDIELHEYYRRSSKARGAWRASRATAGYS
                     SAARRAGDRAGRQARLGNNPELPGARAALGR"
     gene            215713..216222
                     /locus_tag="Y980_0185"
     CDS             215713..216222
                     /locus_tag="Y980_0185"
                     /inference="protein motif:PROSITE:PS00142"
                     /note="Rv0185, (MTCI28.25a) Conserved hypothetical
                     protein, equivalent to CAB08794.1|Z95398|MLCL622_2 from
                     Mycobacterium leprae (168 aa). Contains PS00142 Neutral
                     zinc metallopeptidases, zinc-binding region signature. A
                     core mycobacterial gene; conserved in mycobacterial
                     strains (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01532.1"
                     /db_xref="InterPro:IPR027595"
                     /db_xref="UniProtKB/TrEMBL:L7N5B5"
                     /translation="MIGADVPRDSQRARVYAAEAFVRTLFDRVTAHGSPTVEFFGTQL
                     TLPPEGRFGSVASVQRYVDDVLALPAVGQNWPTVSPVRVRARRAATAAHYENHGGTGT
                     IAVPDRHTAGWAMRELVVLHEVAHHLCQVPPPHGPEFVATVCTLTELVMGPEVGHVFR
                     VVYAQEGVR"
     gene            216267..218342
                     /gene="bglS"
                     /locus_tag="Y980_0186"
     CDS             216267..218342
                     /gene="bglS"
                     /locus_tag="Y980_0186"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0186, (MTCI28.25b) Probable
                     bglS,beta-glucosidase, highly similar to many e.g.
                     BGLS_AGRTU|P27034 beta-glucosidase from Agrobacterium
                     tumefaciens (818 aa). Seems to belong to family 3 of
                     glycosyl hydrolases."
                     /codon_start=1
                     /transl_table=11
                     /product="putative beta-glucosidase BglS (gentiobiase)
                     (cellobiase) (beta-D-glucoside glucohydrolase)"
                     /protein_id="AJF01533.1"
                     /db_xref="GOA:L7N5K3"
                     /db_xref="InterPro:IPR001764"
                     /db_xref="InterPro:IPR002772"
                     /db_xref="InterPro:IPR017853"
                     /db_xref="InterPro:IPR026891"
                     /db_xref="InterPro:IPR026892"
                     /db_xref="UniProtKB/TrEMBL:L7N5K3"
                     /translation="MTDDERFSLLVGLTGASDLWPVRDERIPQGVPMCAGYVPGIPRL
                     GVPALLMSDAGLGVTNPGYRPGDTATALPAGLALAASFNPVLARSSGKAIGREARSRG
                     FNVQLAGAINLARDPRNGRNFEYLSEDPLLSATMAAESIIGIQQQGVIATTKHFSLNC
                     NETNRHWLDAVIDPDAHRESDLLAFEIVIERSQPGAVMAAYNKVNGDYAAGNDHLLND
                     VLKGAWGYRGWVMSDWGGTPSWECALAGLDQECGAQIDAVLWQSEAFTDRLRAAYADG
                     NLPKGRLSDMVRRILRSMFAVGIDRWKPAPAPDMNAHNEIAAQMARQGIVLLQNRGLL
                     PLAPESAGRIAVIGGYAHLGVPAGYGSSAVTPPGGYAGVIPIGGSGLAAGLRNLYLLP
                     SSPLSELRKRLPNAQFEFDPGINPAEAVLAARRADIAIVFAIRAEGEGFDSADLSLPW
                     GQDALIAAVASANANTVVVLETGNPVTMPWRDSVNAIMQAWYPGQAGGQAVAEIVTGQ
                     VNPSGRLPITFPVDLGQTPRSQPPELGAPWGTSTTIHYTEGADVGYRWFASTNQTPMF
                     AFGHGLSYTSFEYRDLVVTGGHTVHASFSVTNTGDRSGADVPQLYMIAAPGESRLRLL
                     GFERVELEPGQTRRVRIEADPRLLARYDGEARSWRIEPGGYTVAVGASAVALKLAAKV
                     KLAGRGFGR"
     gene            complement(218388..218549)
                     /gene="mymT"
                     /locus_tag="Y980_0186A"
     CDS             complement(218388..218549)
                     /gene="mymT"
                     /locus_tag="Y980_0186A"
                     /note="Rv0186A MymT, metallothionein,equivalent to
                     MAV_4993|A0QMH5 hypothetical protein from Mycobacterium
                     avium (strain 104) (51 aa), and MAP_3626c|Q73TU2
                     hypothetical protein from Mycobacterium avium subsp.
                     paratuberculosis (51 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="Metallothionein, MymT"
                     /protein_id="AJF01534.1"
                     /db_xref="GOA:P0CI28"
                     /db_xref="UniProtKB/Swiss-Prot:P0CI28"
                     /translation="MRVIRMTNYEAGTLLTCSHEGCGCRVRIEVPCHCAGAGDAYRCT
                     CGDELAPVK"
     gene            218703..219365
                     /locus_tag="Y980_0187"
     CDS             218703..219365
                     /locus_tag="Y980_0187"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0187, (MTCI28.26) Probable O-methyltransferase,
                     similar to many e.g. AB93458.1|AL357591 putative
                     O-methyltransferase from Streptomyces coelicolor (223 aa);
                     MDMC_STRMY|Q00719 O-methyltransferase from Streptomyces
                     mycarofaciens (221 aa). Also similar to Rv1703c, Rv1220c
                     from Mycobacterium tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="putative O-methyltransferase"
                     /protein_id="AJF01535.1"
                     /db_xref="GOA:L0T2S4"
                     /db_xref="InterPro:IPR002935"
                     /db_xref="UniProtKB/TrEMBL:L0T2S4"
                     /translation="MGMDQQPNPPDVDAFLDSTLVGDDPALAAALAASDAAELPRIAV
                     SAQQGKFLCLLAGAIQARRVLEIGTLGGFSTIWLARGAGPQGRVVTLEYQPKHAEVAR
                     VNLQRAGVADRVEVVVGPALDTLPTLAGGPFDLVFIDADKENNVAYIQWAIRLARRGA
                     VIVVDNVIRGGGILAESDDADAVAARRTLQMMGEHPGLDATAIQTVGRKGWDGFALAL
                     VR"
     gene            219484..219915
                     /locus_tag="Y980_0188"
     CDS             219484..219915
                     /locus_tag="Y980_0188"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0188, (MTCI28.27) Probable conserved
                     transmembrane protein, similar to
                     T35347|4835334|CAB42956.1|AL049863|SC5H1_31 probable
                     membrane protein from Streptomyces coelicolor (147 aa);
                     N-terminus of P80185|MTRC_METTH tetrahydromethanopterin
                     S-methyltransferase subunit C from Methanobacterium
                     thermoautotrophicum strain Marburg/DSM 2133 (266 aa). Also
                     similar to Rv3635 from Mycobacterium tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01536.1"
                     /db_xref="GOA:L7N4G2"
                     /db_xref="InterPro:IPR005530"
                     /db_xref="UniProtKB/TrEMBL:L7N4G2"
                     /translation="MSTVHSSIDQHPDLLALRASFDRAAESTIAHFTFGLALLAGLYV
                     AASPWIVGFSATRGLPTCDLIVGIAVAYLAYGFASALDRTHGMTWTLPVLGVWVIFSP
                     WVLPGVAVTAGMMWSHIIAGAVVAVLGFYFGMRTRAAANQG"
     gene            complement(219994..221721)
                     /gene="ilvD"
                     /locus_tag="Y980_0189c"
     CDS             complement(219994..221721)
                     /gene="ilvD"
                     /locus_tag="Y980_0189c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00886"
                     /note="Rv0189c, (MTCI28.28c) Probable ilvD,dihydroxy-acid
                     dehydratase, similar to many e.g. ILVD_LACLA|Q02139
                     dihydroxy-acid dehydratase (dad) from Lactococcus lactis
                     (subsp. lactis) (Streptococcus lactis) (570 aa). Also
                     similar to ML2608|MLCL622.06c|O06069|ILVD_MYCLE
                     dihydroxy-acid dehydratase from Mycobacterium leprae (564
                     aa). Contains PS00886 Dihydroxy-acid and
                     6-phosphogluconate dehydratases signature 1. Belongs to
                     the ILVD / EDD family. Cofactor: binds 1 4FE-4S cluster
                     (potential)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative dihydroxy-acid dehydratase IlvD (dad)"
                     /protein_id="AJF01537.1"
                     /db_xref="GOA:P65154"
                     /db_xref="InterPro:IPR000581"
                     /db_xref="InterPro:IPR004404"
                     /db_xref="InterPro:IPR015928"
                     /db_xref="InterPro:IPR020558"
                     /db_xref="UniProtKB/Swiss-Prot:P65154"
                     /translation="MPQTTDEAASVSTVADIKPRSRDVTDGLEKAAARGMLRAVGMDD
                     EDFAKPQIGVASSWNEITPCNLSLDRLANAVKEGVFSAGGYPLEFGTISVSDGISMGH
                     EGMHFSLVSREVIADSVEVVMQAERLDGSVLLAGCDKSLPGMLMAAARLDLAAVFLYA
                     GSILPGRAKLSDGSERDVTIIDAFEAVGACSRGLMSRADVDAIERAICPGEGACGGMY
                     TANTMASAAEALGMSLPGSAAPPATDRRRDGFARRSGQAVVELLRRGITARDILTKEA
                     FENAIAVVMAFGGSTNAVLHLLAIAHEANVALSLQDFSRIGSGVPHLADVKPFGRHVM
                     SDVDHIGGVPVVMKALLDAGLLHGDCLTVTGHTMAENLAAITPPDPDGKVLRALANPI
                     HPSGGITILHGSLAPEGAVVKTAGFDSDVFEGTARVFDGERAALDALEDGTITVGDAV
                     VIRYEGPKGGPGMREMLAITGAIKGAGLGKDVLLLTDGRFSGGTTGLCVGHIAPEAVD
                     GGPIALLRNGDRIRLDVAGRVLDVLADPAEFASRQQDFSPPPPRYTTGVLSKYVKLVS
                     SAAVGAVCG"
     gene            221869..222159
                     /locus_tag="Y980_0190"
     CDS             221869..222159
                     /locus_tag="Y980_0190"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0190, (MTCI28.29) Conserved protein,highly
                     similar to several hypothetical proteins e.g.
                     SYCSLRA_35|Q55554|SLL0176 hypothetical 18.9 kDa protein
                     from Synechocystis (167 aa). Also highly similar to
                     Z95398|MLCL622_7|O06070 from Mycobacterium leprae (135
                     aa). Also similar to hypothetical proteins from
                     Mycobacterium tuberculosis e.g. Rv0967, Rv0030, Rv1766."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01538.1"
                     /db_xref="InterPro:IPR003735"
                     /db_xref="UniProtKB/TrEMBL:L7N5P9"
                     /translation="MTAAHGYTQQKDNYAKRLRRVEGQVRGIARMIEEDKYCIDVLTQ
                     ISAVTSALRSVALNLLDEHLSHCVTRAVAEGGPGADGKLAEASAAIARLVRS"
     gene            222287..223528
                     /locus_tag="Y980_0191"
     CDS             222287..223528
                     /locus_tag="Y980_0191"
                     /note="Rv0191, (MTCI28.30) Probable conserved integral
                     membrane protein, member of major facilitator superfamily
                     (MFS) possibly involved in transport of drug,similar to
                     several hypothetical proteins e.g. YDEA_ECOLI|P31122
                     hypothetical 42.5 kd protein from Escherichia coli (396
                     aa); and to several chloramphenicol resistance proteins
                     e.g. CMLR_STRLI|P31141 chloramphenicol resistance protein
                     from Streptomyces lividans (392 aa). Also similar to
                     SVU09991_1 from Mycobacterium tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved integral membrane protein"
                     /protein_id="AJF01539.1"
                     /db_xref="GOA:O07435"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="UniProtKB/Swiss-Prot:O07435"
                     /translation="MTAPTGTSATTTRPWTPRIATQLSVLACAAFIYVTAEILPVGAL
                     SAIARNLRVSVVLVGTLLSWYALVAAVTTVPLVRWTAHWPRRRALVVSLVCLTVSQLV
                     SALAPNFAVLAAGRVLCAVTHGLLWAVIAPIATRLVPPSHAGRATTSIYIGTSLALVV
                     GSPLTAAMSLMWGWRLAAVCVTGAAAAVALAARLALPEMVLRADQLEHVGRRARHHRN
                     PRLVKVSVLTMIAVTGHFVSYTYIVVIIRDVVGVRGPNLAWLLAAYGVAGLVSVPLVA
                     RPLDRWPKGAVIVGMTGLTAAFTLLTALAFGERHTAATALLGTGAIVLWGALATAVSP
                     MLQSAAMRSGGDDPDGASGLYVTAFQIGIMAGALLGGLLYERSLAMMLTASAGLMGVA
                     LFGMTVSQHLFENPTLSPGDG"
     gene            223562..224662
                     /locus_tag="Y980_0192"
     CDS             223562..224662
                     /locus_tag="Y980_0192"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0192, (MTCI28.31) Conserved hypothetical protein.
                     Has Gly- Arg-rich region followed by highly Pro-rich
                     repetitive region near N-terminus. Similar in C-terminus
                     to other hypothetical proteins e.g.
                     Q49706|B1496_F2_81|U00013 from Mycobacterium leprae (271
                     aa); YV09_MYCTU|Q11149|cY20G9.09 hypothetical 47.9 kDa
                     protein from Mycobacterium tuberculosis (451 aa). Also
                     similar to Rv0116c, Rv1433, Rv2518c, Rv0483 from
                     Mycobacterium tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01540.1"
                     /db_xref="GOA:L0T2T1"
                     /db_xref="InterPro:IPR005490"
                     /db_xref="UniProtKB/TrEMBL:L0T2T1"
                     /translation="MPHWAEERHRRESNYVALEAGLDEGESIRRSEHSRSGCGADAGC
                     WRCRGGPGRGSRRSRRSRGPGGTAGPVDPPAVDLLAPPPDPLALPPALDPLAPPPPDP
                     LAPPPPDPLAVPVAAGPVAGQDPTSFVGPPPFRPPTFNPVDGAMVGVAKPIVINFAVP
                     IADRAMAESAIHISSIPPVPGKFYWMSPTQVRWRPFEFWPANTAVNIDAAGTKSSFRT
                     GDSLVATADDATHQMTITRNGVVQKTFPMSMGMVSGGHQTPNGTYYVLEKFATVVMDS
                     STYGVPVNSAQGYKLTVSDAVRIDNSGNFVHSAPWSVADQGKRNVTHGCINLSPANAK
                     WFYDNFGSGDPVVVKNSVGTYNKNDGAQDWQI"
     gene            223605..223907
                     /locus_tag="Y980_0192A"
     CDS             223605..223907
                     /locus_tag="Y980_0192A"
                     /note="Rv0192A Probable N-terminal part of Rv0192, which
                     is member of family P5.17 with Rv0116c,Rv1433, Rv2518c,
                     Rv0483. These are all predicted to be exported/membrane
                     proteins. Rv0192A has typical N-terminal signal peptide
                     which is functional and was identified by PhoA fusion
                     screens: O52054 PGB14T-O1 precursor (fragment 45 AA) (see
                     Chubb et al., 1998). Since Rv0192 misses a signal peptide
                     this suggests that there is a frameshift in the region of
                     the overlap with Rv0192 but none found on reinspection of
                     sequence."
                     /codon_start=1
                     /transl_table=11
                     /product="Conserved secreted protein"
                     /protein_id="AJF01541.1"
                     /db_xref="UniProtKB/TrEMBL:L0T2Y6"
                     /translation="MSRWKQGWTRGSLFAALNIAAVVAVLMLGAGVAVADPDAAPGDP
                     GGPGAPGAQRDPSTRRQLTCWRRHPTRWRCRRHLTRWRRRHLTRSRRPRLTRWQCR"
     gene            complement(224722..226569)
                     /locus_tag="Y980_0193c"
     CDS             complement(224722..226569)
                     /locus_tag="Y980_0193c"
                     /note="Rv0193c, (MTV033.01c-MTCI28.32) Hypothetical
                     unknown protein."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /protein_id="AJF01542.1"
                     /db_xref="UniProtKB/TrEMBL:L0T5Z0"
                     /translation="MIQISRDMSSLGQTATTQALPDNSDGIQLTKFAADDILPLEYAP
                     PIGPELVSQDQLPAAWAYKRFRDLDDKESYRRKLLQELTDALAAQGSEAAEIATAALR
                     DLIDQMAEQGAVVLADIVESDDFLELVKRYDELMAREGSRSFIHRFLDLRRSPGMLTD
                     PAVNGALVHPLMIALISYAVGGPIRMIDARGKDAEPLSVLAQDNMLHIDNTPFNDEYK
                     ILITWRRGTAQGPAGQNFTFLPGTHKLARTCFVNEDGVPWSSENASIFTTPDSIRKVF
                     DAQRQLGGQDHPTVIEVTDSERPLSGVFAAGSLVHHRFRTASGSARSCIILVFHRVAD
                     NPGRMVSDVEDSSDVSLSELLTRGVPDESYQQRFIATLCAAADEIAELLLKWKKTPQR
                     PVSLPLQTKQIDGARFEEWISAATKAPEVREIRNRELTIPYGEVLSAEEFFDLIWRLM
                     RFDKHGPLDLILYHDNREEPRKWARNLIREMSADRLYERLLGWLADIQQPRPADCLRP
                     LQIHALISEVLKTLPLDEDQDPPADWHFDLLGMSHAEAARSVKHLLEDVAEALLRCED
                     MAAYLSTSLFAFWAVDAAYSLDGRRNLVVKDCARRLLRHYTMLSLTCFQ"
     gene            226876..230460
                     /locus_tag="Y980_0194"
     CDS             226876..230460
                     /locus_tag="Y980_0194"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00017"
                     /inference="protein motif:PROSITE:PS00211"
                     /note="Rv0194, (MTV033.02) Probable multidrug efflux pump
                     (See Danilchanka et al., 2008),highly similar to many e.g.
                     U62129|STU62129_2|T30293 ABC transport protein homolog
                     from Salmonella typhi (1218 aa); CAB66302.1|AL136519 ABC
                     transporter protein ATP-binding component from
                     Streptomyces coelicolor (1243 aa); I84547 mdl protein from
                     Escherichia coli (1143 aa); etc. Also similar to MTCY50_9
                     and MTCY50_10 from Mycobacterium tuberculosis. Contains
                     two PS00017 ATP/GTP-binding site motif A (P-loop) and one
                     PS00211 ABC transporters family signature. Belongs to the
                     ATP-binding transport protein family (ABC transporters).
                     Alternative start possible at 1823 but no RBS."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transmembrane multidrug efflux pump"
                     /protein_id="AJF01543.1"
                     /db_xref="GOA:L0T5S9"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR017940"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:L0T5S9"
                     /translation="MRTNCWWRLSGYVMRHRRDLLLGFGAALAGTVIAVLVPLVTKRV
                     IDDAIAADHRPLAPWAVVLVAAAGATYLLMYVRRYYGGRIAHLVQHDLRMDAFQALLR
                     WDGRQQDRWSSGQLIVRTTNDLQLVQALLFDVPNVLRHVLTLLLGVAVMTWLSVPLAL
                     LAVLLVPVIGLIAHRSRRLLAAATHCAQEHKAAVTGVVDAAVCGIRVVKAFGQEERET
                     VKLVTASRALYAAQLRVARLNAHFGPLLQTLPALGQMAVFALGGWMAAQGSITVGTFV
                     AFWACLTLLARPACDLAGMLTIAQQARAGAVRVLELIDSRPTLVDGTKPLSPEARLSL
                     EFQRVSFGYVADRPVLREISLSVRAGETLAVVGAPGSGKSTLASLATRCYDVTQGAVR
                     IGGQDVRELTLDSLRSAIGLVPEDAVLFSGTIGANIAYGRPDATPEQIATAARAAHIE
                     EFVNTLPDGYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSAVDAVIECG
                     IQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDSGRLLDVGTPDEVWERCPRYRELL
                     SPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTNVHNPGPHDHPPGPDPLRRLLREFR
                     GPLALSLLLVAVQTCAGLLPPLLIRHGIDVGIRRHVLSALWWAALAGTATVVIRWVVQ
                     WGSAMVAGYTGEQVLFRLRSVVFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLR
                     TGLVVAVISVVTLVGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRARH
                     RLGTVTATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLALYYPFVA
                     LLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGELAQMFDDYQRAAVA
                     AGRIRSLLSTRTPSSPAARPVGTLRGEVVFDAVHYSYRTREVPALAGINLRIPAGQTV
                     VFVGSTGSGKSTLIKLVARFYDPTHGTVRVDGCDLREFDVDGYRNRLGIVTQEQYVFA
                     GTVRDAIAYGRPDATDAQVERAAREVGAHPMITALDNGYLHQVTAGGRNLSAGQLQLL
                     ALARARLVDPDILLLDEATVALDPATEAVVQRATLTLAARRTTLIVAHGLAIAEHADR
                     IVVLEHGTVVEDGAHTELLAAGGHYSRLWAAHTRLCSPEITQLQCIDA"
     gene            230897..231532
                     /locus_tag="Y980_0195"
     CDS             230897..231532
                     /locus_tag="Y980_0195"
                     /note="Rv0195, (MTV033.03) Possible two-component response
                     regulator, luxR family, similar to many e.g.
                     U00008|ECOHU49_15 regulatory protein narP from Escherichia
                     coli strain K12 (225 aa). Start chosen by similarity.
                     Contains probable helix-turn-helix motif at aa 166-187
                     (Score 1164, +3.15 SD)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative two component transcriptional
                     regulatory protein (probably LuxR-family)"
                     /protein_id="AJF01544.1"
                     /db_xref="GOA:L0T4N0"
                     /db_xref="InterPro:IPR000792"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR016032"
                     /db_xref="UniProtKB/TrEMBL:L0T4N0"
                     /translation="MAPVNVISVAVVASDPLTRDGALARLSSHRELDVRAWQAGCETS
                     VLLVLATTITAPLLCQIEDVQKDGPSHAPKLVVVADEFSAEQVFRMIKLGLTGLLYRS
                     QSTFDCIVETIRLSAEGRLRLPERVQRYLVGRIKSTPTAEPDTPCAAALAEREVAVLR
                     LLADGLSTHQVAVQLNYCERTIKNIVHDIVTRLKLRNRTHAVAHALRAGLI"
     gene            231645..232229
                     /locus_tag="Y980_0196"
     CDS             231645..232229
                     /locus_tag="Y980_0196"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0196, (MTV033.04) Possible transcriptional
                     regulatory protein, similar to two Bacillus subtilis
                     regulators: P42105|YXAF_BACSU hypothetical 21.0 kDa
                     protein (191 aa); and Z99105|BSUB0002_9 negative regulator
                     of the lincomycin operon (188 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein"
                     /protein_id="AJF01545.1"
                     /db_xref="GOA:O53647"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/Swiss-Prot:O53647"
                     /translation="MQGPRERMVVSAALLIRERGAHATAISDVLQHSGAPRGSAYHYF
                     PGGRTQLLCEAVDYAGEHVAAMINEAEGGLELLDALIDKYRQQLLSTDFRAGCPIAAV
                     SVEAGDEQDRERMAPVIARAAAVFDRWSDLTAQRFIADGIPPDRAHELAVLATSTLEG
                     AILLARVRRDLTPLDLVHRQLRNLLLAELPERSR"
     gene            232229..234475
                     /locus_tag="Y980_0197"
     CDS             232229..234475
                     /locus_tag="Y980_0197"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0197, (MTV033.05) Possible oxidoreductase,
                     similar to others e.g.
                     9948789|AAG06102.1|AE004699_7|B83307 probable
                     molybdopterin oxidoreductase from Pseudomonas aeruginosa
                     strain PAO1 (769 aa); 5441785|CAB46809.1|AL096811|T36812
                     probable dehydrogenase from Streptomyces coelicolor (747
                     aa); BAB04334.1|AP001509 assimilatory nitrate reductase
                     (catalytic subunit) from Bacillus halodurans (743 aa);
                     etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01546.1"
                     /db_xref="GOA:L0T2Z1"
                     /db_xref="InterPro:IPR006656"
                     /db_xref="InterPro:IPR006657"
                     /db_xref="InterPro:IPR006963"
                     /db_xref="InterPro:IPR009010"
                     /db_xref="UniProtKB/TrEMBL:L0T2Z1"
                     /translation="MTSSDWLPTACILCECNCGIVVQVDDRRLARIRGDKAHPGSAGY
                     TCNKALRLDHYQNNRARLSSPMRRRADGTYEEIDWDTAIVEIAEGFKQIRDTHGGDKI
                     FYYGGGGQGNHLGGAYSGAFLKALGSRYRSNALAQEKTGEAWVDFQLYGGHTRGEFEN
                     AEVSVFVGKNPWMSQSFPRARVVLNEIAKDPGRSMIVIDPVVTDTAKMADFHLRVQPG
                     CDAWCLAALAAVLVQENLCNEAFLAAHVHGVDTVRAALQEVPVADYAQRCGVDEELLR
                     AAARRIGTAASVSVFEDLGIQQAPNSTVCSYLNKLLWILTGNFAKKGGQHLHSSFAPL
                     FSQVSGRTPVTGAPIIAGLIPGNVVPEEILTEHPDRFRAMIVERGNPAHSLADSAACR
                     AAFQALELMVVVDVAMTETARLAHYVLPAASQFEKPEATFFNFEFPRNGFQLRRPLFP
                     PLPGTLPEPEIWARLVRALGVVDEADLRPLREAAAQGRQAYTEAFLAAAATNPTVAKL
                     TAYVLYETLGPTLPDGLAGAAALWGLAQKTAMAYPDAVRRAGHADGNALFDAILERPS
                     GVTFTVHNYEDDFALISHPDHKIALEIPEMLAEIRSLTQTPSRLTTPQLPIVLSVGER
                     RAYTANDIFRDPSWRKRDANGALRVSVEDAQALGLADGCLARITTAAGSAEATVEVTE
                     TMLAGHAALPNGFGLDYTGDDGRTVVAGVAPNALTSTRWRDPYAGTPWHKHVPAAIRR
                     ADAESPIW"
     gene            complement(234516..236507)
                     /gene="zmp1"
                     /locus_tag="Y980_0198c"
     CDS             complement(234516..236507)
                     /gene="zmp1"
                     /locus_tag="Y980_0198c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00142"
                     /note="Rv0198c, (MTV033.06c) Probable zmp1,zinc
                     metalloprotease, equivalent to Z95398|MLCL622.12c from
                     Mycobacterium leprae (667 aa). Also similar to many other
                     metalloproteases e.g. members of the eukaryotic neprilysin
                     family: P08473|NEP_HUMAN neprilysin (749 aa);
                     Q07744|PEPO_LACLA neutral endopeptidase from Lactococcus
                     lactis (626 aa). Contains PS00142 Neutral zinc
                     metallopeptidases, zinc-binding region signature. Belongs
                     to peptidase family M13 (zinc metalloprotease); also known
                     as the neprilysin subfamily."
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc metalloprotease Zmp1"
                     /protein_id="AJF01547.1"
                     /db_xref="GOA:O53649"
                     /db_xref="InterPro:IPR000718"
                     /db_xref="InterPro:IPR008753"
                     /db_xref="InterPro:IPR018497"
                     /db_xref="InterPro:IPR024079"
                     /db_xref="PDB:3ZUK"
                     /db_xref="UniProtKB/TrEMBL:O53649"
                     /translation="MTLAIPSGIDLSHIDADARPQDDLFGHVNGRWLAEHEIPADRAT
                     DGAFRSLFDRAETQVRDLIIQASQAGAAVGTDAQRIGDLYASFLDEEAVERAGVQPLH
                     DELATIDSAADATELAAALGTLQRAGVGGGIGVYVDTDSKDSTRYLVHFTQSGIGLPD
                     ESYYRDEQHAAVLAAYPGHIARMFGLVYGGESRDHAKTADRIVALETKLADAHWDVVK
                     RRDADLGYNLRTFAQLQTEGAGFDWVSWVTALGSAPDAMTELVVRQPDYLVTFASLWA
                     SVNVEDWKCWARWRLIRARAPWLTRALVAEDFEFYGRTLTGAQQLRDRWKRGVSLVEN
                     LMGDAVGKLYVQRHFPPDAKSRIDTLVDNLQEAYRISISELDWMTPQTRQRALAKLNK
                     FTAKVGYPIKWRDYSKLAIDRDDLYGNVQRGYAVNHDRELAKLFGPVDRDEWFMTPQT
                     VNAYYNPGMNEIVFPAAILQPPFFDPQADEAANYGGIGAVIGHEIGHGFDDQGAKYDG
                     DGNLVDWWTDDDRTEFAARTKALIEQYHAYTPRDLVDHPGPPHVQGAFTIGENIGDLG
                     GLSIALLAYQLSLNGNPAPVIDGLTGMQRVFFGWAQIWRTKSRAAEAIRRLAVDPHSP
                     PEFRCNGVVRNVDAFYQAFDVTEDDALFLDPQRRVRIWN"
     gene            236550..237209
                     /locus_tag="Y980_0199"
     CDS             236550..237209
                     /locus_tag="Y980_0199"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0199, (MTV033.07) Probable conserved membrane
                     protein, equivalent to Z95398|MLCL622.13 from
                     Mycobacterium leprae (224 aa). Also some similarity to
                     Mce-associated membrane proteins from Mycobacterium
                     tuberculosis e.g. Rv0178, Rv0175, etc. A core
                     mycobacterial gene; conserved in mycobacterial strains
                     (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved membrane protein"
                     /protein_id="AJF01548.1"
                     /db_xref="UniProtKB/TrEMBL:L0T5T1"
                     /translation="MPDGEQSQPPAQEDAEDDSRPDAAEAAAAEPKSSAGPMFSTYGI
                     ASTLLGVLSVAAVVLGAMIWSAHRDDSGERTYLTRVMLTAAEWTAVLINMNADNIDAS
                     LQRLHDGTVGQLNTDFDAVVQPYRQVVEKLRTHSSGRIEAVAIDTVHRELDTQSGAAR
                     PVVTTKLPPFATRTDSVLLVATSVSENAGAKPQTVHWNLRLDVSDVDGKLMISRLESI
                     R"
     gene            237206..237895
                     /locus_tag="Y980_0200"
     CDS             237206..237895
                     /locus_tag="Y980_0200"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0200, (MTV033.08) Possible conserved
                     transmembrane protein, equivalent to Z95398|MLCL622.14
                     from Mycobacterium leprae (229 aa). Also some similarity
                     to Rv1973 from Mycobacterium tuberculosis (160 aa); and
                     Rv1362c|Z75555|MTCY02B10_26 (220 aa). A core mycobacterial
                     gene; conserved in mycobacterial strains (See Marmiesse et
                     al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01549.1"
                     /db_xref="GOA:L7N5T8"
                     /db_xref="UniProtKB/TrEMBL:L7N5T8"
                     /translation="MRNAWRLVVFDVLAPLATIAALAAIGVLLGWPLWWVSTCSVLVL
                     LVVEGVAINFWLLRRDSVTVGTDDDAPGLRLAVVFLCAAAISAAVVTGYLRWTTPDRD
                     FNRDSREVVHLATGMAETVASFSPSAPAAAVDRAAAMMVPEHAGGFKEQYAKSSADLA
                     RRGVTAQAATLAAGVEAIGPSAASVAVILRVSQSIPGQPTSQAARALRVTLTKRGSGW
                     LVLDVTPINAR"
     gene            complement(237892..238395)
                     /locus_tag="Y980_0201c"
     CDS             complement(237892..238395)
                     /locus_tag="Y980_0201c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0201c, (MTV033.09c) Conserved protein, equivalent
                     to Z95398|MLCL622.15c from Mycobacterium leprae (170 aa).
                     A core mycobacterial gene; conserved in mycobacterial
                     strains (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01550.1"
                     /db_xref="UniProtKB/TrEMBL:L0T2T8"
                     /translation="MTLAAEPHPAPPQQPTVAWSEPDVDRRVEFWPTVAIRSALESGD
                     IATWQRIAAALKRDPYGRTARQVEEVLEGIPATGIANAFWEVLDRARTHLDANERAEV
                     ARQVGLLLDRSGLQRQEFASRIGVTAQDLTAYLDGIVSPSASLMIRMRRLSDRFVRAK
                     SVRAADS"
     gene            complement(238392..241292)
                     /gene="mmpL11"
                     /locus_tag="Y980_0202c"
     CDS             complement(238392..241292)
                     /gene="mmpL11"
                     /locus_tag="Y980_0202c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0202c, (MTV033.10c) Probable mmpL11,conserved
                     transmembrane transport protein (see citation below),
                     equivalent to Z95398|MLCL622.16c from Mycobacterium leprae
                     (1014 aa). Member of RND superfamily,similar to several
                     putative transport proteins e.g. P96687 from Bacillus
                     subtilis (724 aa); etc. Belongs to the MmpL family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane transport
                     protein MmpL11"
                     /protein_id="AJF01551.1"
                     /db_xref="GOA:P65374"
                     /db_xref="InterPro:IPR000731"
                     /db_xref="InterPro:IPR004869"
                     /db_xref="UniProtKB/Swiss-Prot:P65374"
                     /translation="MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEV
                     AGSQSLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDNAVALLRQIASELPGVTE
                     APNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVKGDQSGQTANGKVRLYV
                     IGQGALSAAAAANTKHDIANAERWNLPIILMVLVAVFGSLAAAAIPLALAVCTVVITM
                     GLVFVLSMHTTMSVFVTSTVSMFGIALAVDYSLFILMRYREELRCGRRPPDAVDAAMA
                     TSGLAVVLSGMTVIASLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFA
                     RAAAKRSALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPATLMVL
                     GNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAGGASAPEHSQTIAAIRH
                     RIAQAPNVVSVAPPRFADDNGSALLSAVLSVDPEDLGARDTITWMRTQLPRVAGAAQV
                     DVGGPTALIKDFDDRVSATQPLVLVFVAVIAFLMLLISIRSVFLAFKGVLMTLLSVAA
                     AYGSLVMVFQWGWARGLGFPALHSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQ
                     TGQTRDAVAYGVRTSARTITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATV
                     VRLVLVPALMAMFDRWNWWLPRWLAHILPSVDFDRPLPKVDLGDVVVIPDDFAAAIPP
                     SADVRMVLKSAAKLKRLAPDAICVTDPLAFTGCGCDGKALDQVQLAYRNGIARAISWG
                     QRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRAGPGYRRRSPVETTNVALPTGDR
                     LQIPTGAETLRFKGYLIMSRNSSHDYADFADLVDTMAPETAAAVLAGMDRYYSCQAPG
                     RQWMATQLVGRLADPQPSDLGDQSPGADAQAKWEEVRRRCLSVAVAMLEEAR"
     gene            241514..241924
                     /locus_tag="Y980_0203"
     CDS             241514..241924
                     /locus_tag="Y980_0203"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0203, (MTV033.11) Possible exported protein (has
                     hydrophobic stretch near N-terminus). Some similarity to
                     part of U02459|LDU02459_1 hypothetical protein from
                     Leishmania donovani (741 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative exported protein"
                     /protein_id="AJF01552.1"
                     /db_xref="GOA:O53654"
                     /db_xref="PDB:3MAY"
                     /db_xref="UniProtKB/TrEMBL:O53654"
                     /translation="MKTGTATTRRRLLAVLIALALPGAAVALLAEPSATGASDPCAAS
                     EVARTVGSVAKSMGDYLDSHPETNQVMTAVLQQQVGPGSVASLKAHFEANPKVASDLH
                     ALSQPLTDLSTRCSLPISGLQAIGLMQAVQGARR"
     gene            complement(241976..243214)
                     /locus_tag="Y980_0204c"
     CDS             complement(241976..243214)
                     /locus_tag="Y980_0204c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0204c, (MTV033.12c) Probable conserved
                     transmembrane protein (see citation below),equivalent, but
                     has C-terminal extension, to Z95398|MLCL622.17c from
                     Mycobacterium leprae (367 aa). Some similarity to Rv0585c
                     from Mycobacterium tuberculosis. Nucleotide position
                     242299 in the genome sequence has been corrected, C:G
                     resulting in V306L."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01553.1"
                     /db_xref="GOA:Q7DAA0"
                     /db_xref="InterPro:IPR022791"
                     /db_xref="UniProtKB/TrEMBL:Q7DAA0"
                     /translation="MSHDAPARNLRQRVGALPRTRVGAPPAEGVPPRGKYWWLRWAVL
                     AIVAIVLAIEVALGWDQLAKAWVSLYRAKWWWLLAAVAAAGASMHSFAQIQRTLLKSA
                     GVHVKQWRSEAAFYAANSLSTTLPGGPVLSATFLLRQQRIWGASTVVASWQLVMSGVL
                     QAVGLALLGLGGAFFLGAKNNPFSLLFTLGGFVTLLLLAQAVASRPELIEGIGRRVLS
                     WANSVRGRPADAGLPKWRETLMQLESVSLGRRDLGVAFGWSLFNWIADVACLGFAAYA
                     AGDHASVGGLAVAYAAARAVGTIPLMPGGLLVVEAVLVPGLVSSGMPLPSAISAMLIY
                     RLISWLLIAAIGWVVFFFMFRTESTADSDNDRDPPTDPNLRLVIQPQGTPCDDPVETT
                     PQGPAPTPDLRPEGGETPPR"
     gene            243384..244487
                     /locus_tag="Y980_0205"
     CDS             243384..244487
                     /locus_tag="Y980_0205"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0205, (MTV033.13) Possible conserved
                     transmembrane protein, similar to hypothetical proteins
                     from many bacteria e.g. AL0209|SC4H8_6 from Streptomyces
                     coelicolor (402 aa); Z99117|BSUB0014_221 from Bacillus
                     subtilis (353 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01554.1"
                     /db_xref="GOA:O53656"
                     /db_xref="InterPro:IPR002549"
                     /db_xref="UniProtKB/Swiss-Prot:O53656"
                     /translation="MSASLDDASVAPLVRKTAAWAWRFLVILAAMVALLWVLNKFEVI
                     VVPVLLALMLSALLVPPVDWLDSRGLPHAVAVTLVLLSGFAVLGGILTFVVSQFIAGL
                     PHLVTEVERSIDSARRWLIEGPAHLRGEQIDNAGNAAIEALRNNQAKLTSGALSTAAT
                     ITELVTAAVLVLFTLIFFLYGGRSIWQYVTKAFPASVRDRVRAAGRAGYASLIGYARA
                     TFLVALTDAAGVGAGLAVMGVPLALPLASLVFFGAFIPLIGAVVAGFLAVVVALLAKG
                     IGYALITVGLLIAVNQLEAHLLQPLVMGRAVSIHPLAVVLAIAAGGVLAGVVGALLAV
                     PTVAFFNNAVQVLLGGNPFADVADVSSDHLTEV"
     gene            complement(244484..247318)
                     /gene="mmpL3"
                     /locus_tag="Y980_0206c"
     CDS             complement(244484..247318)
                     /gene="mmpL3"
                     /locus_tag="Y980_0206c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0206c, (MTV033.14c, MTCY08D5.01c) Possible mmpL3,
                     conserved transmembrane transport protein (see Tekaia et
                     al., 1999), equivalent to Z95398|MLCL622.18c from
                     Mycobacterium leprae (955 aa). Member of RND superfamily,
                     similar to others. Belongs to the MmpL family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane transport
                     protein MmpL3"
                     /protein_id="AJF01555.1"
                     /db_xref="GOA:O53657"
                     /db_xref="InterPro:IPR000731"
                     /db_xref="InterPro:IPR004869"
                     /db_xref="UniProtKB/Swiss-Prot:O53657"
                     /translation="MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFY
                     DDGSQSVQASVLGDQVYGRDRSGHIVAIFQAPAGKTVDDPAWSKKVVDELNRFQQDHP
                     DQVLGWAGYLRASQATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGT
                     VKLAGLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIA
                     GALGIMRFLAIFGPVHYFAQPVVSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRR
                     TVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVMLSAILSITVLPACLG
                     ILGKHVDALGVRTLFRVPFLANWKISAAYLNWLADRLQRTKTREEVEAGFWGKLVNRV
                     MKRPVLFAAPIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTN
                     PLTLVIQTSNHQPVTDAQIADIRSKAMAIGGFIEPDNDPANMWQERAYAVGASKDPSV
                     RVLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMPLMVVIL
                     LTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTA
                     PVIGLIIALVFGLSTDYEVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVA
                     VVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVPSVMKLLGDDCWWAPRWARRL
                     QTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAGDPRPPHDPTHPLAESPRP
                     ARSSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPTTRLAAAGRSVQSPAST
                     PPPTPTPPSAPSAGQTRAMPLAANRSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLN
                     ARGTSDKTRQRRRGGGALSAQDLLRREGRL"
     gene            complement(247384..248112)
                     /locus_tag="Y980_0207c"
     CDS             complement(247384..248112)
                     /locus_tag="Y980_0207c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0207c, (MTCY08D5.02c) Conserved hypothetical
                     protein, equivalent to Z95398|MLCL622_19 from
                     Mycobacterium leprae (261 aa). A core mycobacterial gene;
                     conserved in mycobacterial strains (See Marmiesse et
                     al.,2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01556.1"
                     /db_xref="InterPro:IPR021139"
                     /db_xref="UniProtKB/TrEMBL:L0T300"
                     /translation="MSLTEDVTSQTSESLARHSVLAEDLSQDGLTSLGAPGARVLLVW
                     DAPNLDMGLGSILGRRPTALERPRFDALGRWLLARTAEIVAGRPGISTEPEATVFTNI
                     APGSAEVVRPWVDALRNVGFAVFAKPKVDEDSDVDRDMLAHIDERYREGLAALVVASA
                     DGQAFRQPLEAVARSGTPVQVLGFREHASWALASDTLEFVDLEDIAGVFREPLPRIGL
                     DSLPEQGAWLQPFRPLSSLLTSRV"
     gene            complement(248115..248906)
                     /locus_tag="Y980_0208c"
     CDS             complement(248115..248906)
                     /locus_tag="Y980_0208c"
                     /note="Rv0208c, (MTCY08D5.03c) Hypothetical
                     methyltransferase, equivalent to Z95398|MLCL622_20 from
                     Mycobacterium leprae (279 aa). Also similar to others e.g.
                     10178368|CAC08407.1|AL392177|Q9F305|MT04_STRCO|SCD17A.03c
                     hypothetical methlytransferase from Streptomyces
                     coelicolor (271 aa). Could start at aa 7."
                     /codon_start=1
                     /transl_table=11
                     /product="putative methyltransferase (methylase)"
                     /protein_id="AJF01557.1"
                     /db_xref="GOA:P67498"
                     /db_xref="InterPro:IPR003358"
                     /db_xref="UniProtKB/Swiss-Prot:P67498"
                     /translation="MVHHGQMHAQPGVGLRPDTPVASGQLPSTSIRSRRSGISKAQRE
                     TWERLWPELGLLALPQSPRGTPVDTRAWFGRDAPVVLEIGSGSGTSTLAMAKAEPHVD
                     VIAVDVYRRGLAQLLCAIDKVGSDGINIRLILGNAVDVLQHLIAPDSLCGVRVFFPDP
                     WPKARHHKRRLLQPATMALIADRLVPSGVLHAATDHPGYAEHIAAAGDAEPRLVRVDP
                     DTELLPISVVRPATKYERKAQLGGGAVIELLWKKHGCSERDLKIR"
     gene            249038..250123
                     /locus_tag="Y980_0209"
     CDS             249038..250123
                     /locus_tag="Y980_0209"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0209, (MTCY08D5.04) Hypothetical unknown
                     protein."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /protein_id="AJF01558.1"
                     /db_xref="UniProtKB/TrEMBL:L7N4J4"
                     /translation="MRGQGHQIFVDELARFATSSADQRVVAIAQRAAEPLRVAVRGRP
                     GVGCRTVARALQGAGSSSGMTVTPQARAADSDVDLVVYVTVEVVKPEDREAIAATRRP
                     VVAVLNKADLAGPLSGAGPIVMAQARCAQFSTLLGVPMESMIGLLAVAALDDLDDTLR
                     AVLRALAAHPDGFDALDRAVAGFLAAALPVPTEVRLRLLDTLDLFGIALGMAAFRPGR
                     PSRTPAQLRTLLRRVSGVDAVIDKVTAAGSEVRYRRLLDAVAELEALAAQAKEIGGPI
                     GEFLRDDDTVLARMAAAVDVALAVGLDVGPLDDPAAHLPRAVRWHRYSLDNGDMHRTC
                     GADIARGSLRLWSLAGGMPLHRYRKSS"
     gene            250120..251598
                     /locus_tag="Y980_0210"
     CDS             250120..251598
                     /locus_tag="Y980_0210"
                     /note="Rv0210, (MTCY08D5.05) Hypothetical unknown protein.
                     Possibly membrane protein; has hydrophobic stretches
                     around aa 333 - 381."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /protein_id="AJF01559.1"
                     /db_xref="UniProtKB/TrEMBL:L0T4P5"
                     /translation="MIRAASDDPAGVDELVAAIAPGLAGLGLPVINRREVVLVTGPWL
                     AGVSGVRAALAERLPQRRFVETAELGPGDAPVAVVFVVSAATALTESDCVLLDTAAEH
                     TDAVVAVVSKIDVHRGWRDVLTSNRDRLAARASRYARVPWVGAAAAPELGEPYLDDLV
                     AAIQKQLADPAVARRNMLRAWESRLLMVARRFDGDAQSAGRRARVDALRQQRRTVLRQ
                     GRQSKSEHTIALRAQIQHARVKLSYFARNRCSLLRVELQEHVAGLSRKDIARFAAYTR
                     GRVQEVVAEVGEGAVAHLADVAQLLGVPVQPPVLENLPAVLPTVVAPPLTSRRLEIRL
                     TTLLGAGFGLGIALTLSRLVAGLTPGLAASGMVAGVAIGLAVTAWVVNARALLHDRVV
                     VDRWTGEVTASLRSVVEQLVATRVVAVETLLSTAISERDDAENARVADQVSIIDGELR
                     EHAVAAARAAALRDREMPAVRAALEAVRAELGEPGAPTTGLF"
     gene            251782..253602
                     /gene="pckA"
                     /locus_tag="Y980_0211"
                     /gene_synonym="pck1"
                     /gene_synonym="pckG"
     CDS             251782..253602
                     /gene="pckA"
                     /locus_tag="Y980_0211"
                     /gene_synonym="pck1"
                     /gene_synonym="pckG"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00505"
                     /note="Rv0211, (MTCY08D5.06) Probable pckA (alternate gene
                     names: pckG and pck1), iron-regulated phosphoenolpyruvate
                     carboxykinase [GTP], equivalent to Z95398|MLCL622_21
                     probable phosphoenolpyruvate carboxykinase from
                     Mycobacterium leprae (609 aa). Also highly similar to
                     others e.g. PPCK_NEOFR|P22130 phosphoenolpyruvate
                     carboxykinase [GTP] (608 aa). Contains PS00505
                     Phosphoenolpyruvate carboxykinase (GTP) signature. Belongs
                     to the phosphoenolpyruvate carboxykinase [GTP] family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative iron-regulated phosphoenolpyruvate
                     carboxykinase [GTP] PckA (phosphoenolpyruvate carboxylase)
                     (PEPCK)(pep carboxykinase)"
                     /protein_id="AJF01560.1"
                     /db_xref="GOA:P65686"
                     /db_xref="InterPro:IPR008209"
                     /db_xref="InterPro:IPR008210"
                     /db_xref="InterPro:IPR013035"
                     /db_xref="InterPro:IPR018091"
                     /db_xref="UniProtKB/Swiss-Prot:P65686"
                     /translation="MTSATIPGLDTAPTNHQGLLSWVEEVAELTQPDRVVFTDGSEEE
                     FQRLCDQLVEAGTFIRLNPEKHKNSYLALSDPSDVARVESRTYICSAKEIDAGPTNNW
                     MDPGEMRSIMKDLYRGCMRGRTMYVVPFCMGPLGAEDPKLGVEITDSEYVVVSMRTMT
                     RMGKAALEKMGDDGFFVKALHSVGAPLEPGQKDVAWPCSETKYITHFPETREIWSYGS
                     GYGGNALLGKKCYSLRIASAMAHDEGWLAEHMLILKLISPENKAYYFAAAFPSACGKT
                     NLAMLQPTIPGWRAETLGDDIAWMRFGKDGRLYAVNPEFGFFGVAPGTNWKSNPNAMR
                     TIAAGNTVFTNVALTDDGDVWWEGLEGDPQHLIDWKGNDWYFRETETNAAHPNSRYCT
                     PMSQCPILAPEWDDPQGVPISGILFGGRRKTTVPLVTEARDWQHGVFIGATLGSEQTA
                     AAEGKVGNVRRDPMAMLPFLGYNVGDYFQHWINLGKHADESKLPKVFFVNWFRRGDDG
                     RFLWPGFGENSRVLKWIVDRIEHKAGGATTPIGTVPAVEDLDLDGLDVDAADVAAALA
                     VDADEWRQELPLIEEWLQFVGEKLPTGVKDEFDALKERLG"
     gene            complement(253669..254640)
                     /gene="nadR"
                     /locus_tag="Y980_0212c"
                     /gene_synonym="nadI"
     CDS             complement(253669..254640)
                     /gene="nadR"
                     /locus_tag="Y980_0212c"
                     /gene_synonym="nadI"
                     /inference="protein motif:PROSITE:PS00017"
                     /note="Rv0212c, (MTCY08D5.07c) Possible nadR (alternate
                     gene name: nadI), transcriptional regulator,similar to
                     others e.g. NADR_ECOLI|P27278 transcriptional regulator
                     from Escherichia coli (410 aa). Contains PS00017
                     ATP/GTP-binding site motif A (P-loop)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein NadR
                     (probably AsnC-family)"
                     /protein_id="AJF01561.1"
                     /db_xref="GOA:L0T304"
                     /db_xref="InterPro:IPR004821"
                     /db_xref="InterPro:IPR006417"
                     /db_xref="InterPro:IPR014729"
                     /db_xref="InterPro:IPR016429"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:L0T304"
                     /translation="MTHGMVLGKFMPPHAGHVYLCEFARRWVDELTIVVGSTAAEPIP
                     GAQRVAWMRELFPFDRVVHLANENPQRPWEHPDFWDIWKASLQGVLATRPDFVFGAEP
                     YNADFAQVLGARFVAVDHGRTVVPVTATDIRADPLGHWQHIPRCVRPAFVKRVSIIGP
                     ESTGKTTLAQAVAEKLRTKWVPERAKMLRELNGGSLIGLEWAEIVRGQIASEEALARD
                     ADRVLICDTDPLATTVWAEFLAGGCPQELRDLARRPYDLTLLTTPDVPWDADDGRCVP
                     GARGTFFARCEQALRAAGRSFVVITGGWEERLSVSLRAVEELVRARR"
     gene            complement(254637..255950)
                     /locus_tag="Y980_0213c"
     CDS             complement(254637..255950)
                     /locus_tag="Y980_0213c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0213c, (MTCY08D5.08c) Possible methyltransferase,
                     weakly similar to others methyltransferases e.g.
                     AF127374_30|LINA from Streptomyces lavendulae (611 aa);
                     Q50258 fortimicin kl1 methyltransferase (553 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative methyltransferase (methylase)"
                     /protein_id="AJF01562.1"
                     /db_xref="GOA:L7N4V3"
                     /db_xref="InterPro:IPR006158"
                     /db_xref="InterPro:IPR006638"
                     /db_xref="InterPro:IPR007197"
                     /db_xref="InterPro:IPR023404"
                     /db_xref="InterPro:IPR023970"
                     /db_xref="UniProtKB/TrEMBL:L7N4V3"
                     /translation="MSIKAYAKTQGIAVTSVNGLVAGHGSVQETWLAMQSAAALSGTP
                     RLVGFSCIDTFPEVLWLAQRARQAWDGVRIVIGNAMATLNYERILRQHDCFDYVVVGD
                     GEVAFTKLALALANDAAVDDVPGLARRSEQGQILRTPSSLVDLDELPRPARDELPTVL
                     ADGFAASVFSTRGCPYRCTFCGTGAMSAMLGKDSYRAKSVDAVVDEIDYLVSDYDVNF
                     LSITDDLFISKHPGSQQRAADFANAVLRRGISVNFMVDIRLDSVVDLDLFKHLHRAGL
                     RRVFIGVETGSYEQLRAYRKQILTRGQDAADTINALQQLGIDVIPGTIMFHPTVQPDE
                     LRETVRLLRATKYTVGFKFMSRIVPYPGTPLYQAYSDAGYLTAKWPLGQWEFVDPEAS
                     RVYADVVAKVAPDVGISFDEAEAYFLSRLDEWENVIAGRIAEATS"
     gene            256064..257677
                     /gene="fadD4"
                     /locus_tag="Y980_0214"
     CDS             256064..257677
                     /gene="fadD4"
                     /locus_tag="Y980_0214"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00455"
                     /note="Rv0214, (MTCY08D5.09) Probable fadD4,fatty-acid-CoA
                     synthetase, similar to many e.g. 4CL_PINTA|P41636
                     4-coumarate--CoA ligase (537 aa). Also similar to others
                     from Mycobacterium tuberculosis e.g. MTCY6A4.14,
                     MTCY493_27, MTCY07A7_11, MTCI28_6. Contains PS00455
                     putative AMP-binding domain signature."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fatty-acid-CoA ligase FadD4
                     (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)"
                     /protein_id="AJF01563.1"
                     /db_xref="GOA:L7N5T5"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="UniProtKB/TrEMBL:L7N5T5"
                     /translation="MPRGELYKRFRLVMGGIAPCGSGRRAATYPRRMQIRPYIGADKP
                     AVILYPSGTVISFDELEARANRLAHWFRQAGLREDDVVAILMENNEHVHAVMWAARRS
                     GLYYVPINTHLTASEAAYIVDNSGAKAIVGSAALRETCHGLAEHLPGGLPDLLMLAGG
                     GLVGWMTYPECVADQPDTPIEDEREGDLLQYSSGTTGRPKGIKRELPHVSPDAAPGMM
                     PALLDFWMDADSVYLSPAPMYHTAPSVWTMSALAAGVTTVVMEKFDAEGALDAIQRYR
                     VTHAQFVPAMFVRMLKLPEAVRNSYDMSSLRRVIHAAAPCPVQIKEQMIHWWGPIIDE
                     YYASSEASGSTLITAEDWLTHPGSVGKPIQGGVHIVGADGSELPPNQPGEIYFEGGYP
                     FEYLNDPAKTAASRNKHGWVTVGDVGYLDDDGYLFLTGRRHHMIISGGVNIYPQEAEN
                     LLVAHPKVLDAAVFGVPDDEMGQRVMAAVQTVDSADANDQFAGELLAWLRDRLSHFKC
                     PRSIAFEPQLPRTDTGKLYKSGLVEKYSV"
     gene            complement(257783..258856)
                     /gene="fadE3"
                     /locus_tag="Y980_0215c"
     CDS             complement(257783..258856)
                     /gene="fadE3"
                     /locus_tag="Y980_0215c"
                     /note="Rv0215c, (MTCY08D5.10c) Probable fadE3, acyl-
                     dehydrogenase, similar to many e.g. ACDB_BACSU|P45857
                     acyl-CoA dehydrogenase from B. subtilis (379 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA dehydrogenase FadE3"
                     /protein_id="AJF01564.1"
                     /db_xref="GOA:L0T4Q2"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR006092"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="UniProtKB/TrEMBL:L0T4Q2"
                     /translation="MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEAWIEQ
                     MKHIGIYGLAIDEQYGGSPVSMPCYVQVTQELARGWMSLAGAMGGHTVVAKLLTLFGT
                     EEQRRTYLPPMASGELRATMALTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWI
                     SNARRSGLFAVLCKTDPNATPRHQGMSIVLVEPGPGLTVSRDLPKLGYKGVESCELSF
                     DNLRVPVSAILGGAMGQGFSQMMKGLETGRIQVAARALGVATAALEDSLAYAQQRESF
                     GRPIWQHQAVGNYLADMATKLTAARQLTRYAAERYDSGQRCDMEAGMAKLFASEVAME
                     IALNAVRIHGGYGYSTEYDVERR"
     gene            258913..259926
                     /locus_tag="Y980_0216"
     CDS             258913..259926
                     /locus_tag="Y980_0216"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0216, (MTCY08D5.11) Double hotdog R-specific
                     hydratase of unknown function, shows no activity for
                     crotonyl-CoA, equivalent to Z95398|MLCL622_22 from
                     Mycobacterium leprae (339 aa). Shows structural similarity
                     to six others in Mycobacterium tuberculosis (see Castell
                     et al (2005) below). A core mycobacterial gene; conserved
                     in mycobacterial strains (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="Double hotdog hydratase"
                     /protein_id="AJF01565.1"
                     /db_xref="GOA:P96398"
                     /db_xref="InterPro:IPR016790"
                     /db_xref="PDB:2BI0"
                     /db_xref="UniProtKB/TrEMBL:P96398"
                     /translation="MASGYGGIRVGGPYFDDLSKGQVFDWAPGVTLSLGLAAAHQSIV
                     GNRLRLALDSDLCAAVTGMPGPLAHPGLVCDVAIGQSTLATQRVKANLFYRGLRFHRF
                     PAVGDTLYTRTEVVGLRANSPKPGRAPTGLAGLRMTTIDRTDRLVLDFYRCAMLPASP
                     DWKPGAVPGDDLSRIGADAPAPAADPTAHWDGAVFRKRVPGPHFDAGIAGAVLHSTAD
                     LVSGAPELARLTLNIAATHHDWRVSGRRLVYGGHTIGLALAQATRLLPNLATVLDWES
                     CDHTAPVHEGDTLYSELHIESAQAHADGGVLGLRSLVYAVSDSASEPDRQVLDWRFSA
                     LQF"
     gene            complement(259923..260831)
                     /gene="lipW"
                     /locus_tag="Y980_0217c"
     CDS             complement(259923..260831)
                     /gene="lipW"
                     /locus_tag="Y980_0217c"
                     /note="Rv0217c, (MTCY08D5.12c) Possible esterase, showing
                     similarity with others e.g. EST_ACICA|P18773 esterase (303
                     aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative esterase LipW"
                     /protein_id="AJF01566.1"
                     /db_xref="GOA:L0T308"
                     /db_xref="InterPro:IPR013094"
                     /db_xref="UniProtKB/TrEMBL:L0T308"
                     /translation="MSGNEVHPDLRRIAVVTPRQLVGPRTLPVMRALIVVAGLRMSRT
                     PPDIEVLTLESGVGVRLYRPAGSNEPAPALLWIHAGGYVMGTAQQDDRLCLRFSSRLG
                     ITVASVDYRLAPENPYPAALGDCYSALTWLASLPAVDPARVAIGGASAGGGLAAALAL
                     LARDRGGITPAFQLLVYPMLDDRPSIAPANPHYRLWNGRANRFGWRAYLGDADARVAV
                     PGRRDDLGGLAPAWIGVGTHDLLHDEDLAYAERLTAAGVPCQVEVVEGAFHGFDRVAP
                     NVGVSQRFFTSQCNSLRAALALSNRT"
     gene            260924..262252
                     /locus_tag="Y980_0218"
     CDS             260924..262252
                     /locus_tag="Y980_0218"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0218, (MTCY08D5.13) Probable conserved
                     transmembrane protein, some similarity with sulfite
                     oxidases e.g. SUOX_HUMAN|P51687 sulfite oxidase precursor
                     (488 aa); and with some nitrate reductases e.g.
                     NIA_FUSOX|P39863 nitrate reductase (NADPH) (905 aa). Also
                     similar to BSUB0017_86 from Mycobacterium tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01567.1"
                     /db_xref="GOA:L0T609"
                     /db_xref="InterPro:IPR000572"
                     /db_xref="UniProtKB/TrEMBL:L0T609"
                     /translation="MSDPARGAEAEDAYGFPAGLWRWLQRHPPPALHRLTRFRSPLRG
                     PWLTSVFGLVLLVALPFVIITGLLSYIAYAPQLGQAIPGDVGWLRLPAFTWPTRPSWL
                     YRLTQGLHVGLGLVIIPVVLAKLWSVIPRLFVWPPARSIAQVLERLSVLMLVGGILFQ
                     IVTGVLNIQYDYIFGFSFYTGHYFGAWVFIAGFLLHIVVKIPHMVTGLRSIPMREVLG
                     TNVADTRAQPCDPDGLVSVNPGEATLSRRGALGLVGAGVLLIGVLTVGQTLGGFTRKA
                     ALLLPRGRVVSPGDFPVNKTAAAAGITAEAIGPDWRLVLCGGPAEVVLDRATLAGLPQ
                     RTARLPLACVEGWSAVRTWSGVPLAELALLAGVPAARSARVTSLQRGGAFGEAKLAAN
                     QIADPDALLALRVDGADLSLDHGYPARIIVPALPGVHNTKWVAGIEFHKR"
     gene            262254..262802
                     /locus_tag="Y980_0219"
     CDS             262254..262802
                     /locus_tag="Y980_0219"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0219, (MTCY08D5.14) Probable conserved
                     transmembrane protein, showing similarity with
                     CAB76992.1|AL159178 putative lipoprotein from Streptomyces
                     coelicolor (163 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01568.1"
                     /db_xref="GOA:L7N4A1"
                     /db_xref="UniProtKB/TrEMBL:L7N4A1"
                     /translation="MFDIATRFKNSYGSGPLHLLAMVSGFALLGYIVATARPSALWNQ
                     ATWWQSIAVWFVAAVVAHDLLLYPLYALADRILARLVGRRDVSAPRRRPELPVRNYIR
                     IPALAAGLTLLVFLPGIIRQGAPTYLDATGQTQEPFLGRWLLLTAVAFGISAAAYAIR
                     LVVAHVRRRRAGCSRVDAIDEE"
     gene            262812..264023
                     /gene="lipC"
                     /locus_tag="Y980_0220"
     CDS             262812..264023
                     /gene="lipC"
                     /locus_tag="Y980_0220"
                     /inference="protein motif:PROSITE:PS00122"
                     /note="Rv0220, (MTCY08D5.15) Probable esterase, similar to
                     others proteins and esterases from various organisms and
                     Mycobacterium tuberculosis e.g. Q50681 (431 aa); Rv1426c,
                     Rv1399c, etc. Contains PS00122 Carboxylesterases type-B
                     serine active site."
                     /codon_start=1
                     /transl_table=11
                     /product="putative esterase LipC"
                     /protein_id="AJF01569.1"
                     /db_xref="GOA:L7N4U2"
                     /db_xref="InterPro:IPR013094"
                     /db_xref="InterPro:IPR019826"
                     /db_xref="UniProtKB/TrEMBL:L7N4U2"
                     /translation="MNQRRAAGSTGVAYIRWLLRARPADYMLALSVAGGSLPVVGKHL
                     KPLGGVTAIGVWGARHASDFLSATAKDLLTPGINEVRRRDRASTQEVSVAALRGIVSP
                     DDLAVEWPAPERTPPVCGALRHRRYVHRRRVLYGDDPAQLLDVWRRKDMPTKPAPVLI
                     FVPGGAWVHGSRAIQGYAVLSRLAAQGWVCLSIDYRVAPHHRWPRHILDVKTAIAWAR
                     ANVDKFGGDRNFIAVAGCSAGGHLSALAGLTANDPQYQAELPEGSDTSVDAVVGIYGR
                     YDWEDRSTPERARFVDFLERVVVQRTIDRHPEVFRDASPIQRVTRNAPPFLVIHGSRD
                     CVIPVEQARSFVERLRAVSRSQVGYLELPGAGHGFDLLDGARTGPTAHAIALFLNQVH
                     RSRAQFAKEVI"
     gene            264067..265476
                     /locus_tag="Y980_0221"
     CDS             264067..265476
                     /locus_tag="Y980_0221"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0221, (MTCY08D5.16) Possible triacylglycerol
                     synthase (See Daniel et al., 2004), similar to other
                     proteins from Mycobacterium tuberculosis e.g.
                     Q50680|Rv2285|MT2343|MTCY339.25c 47.7 kDa protein (445
                     aa); Rv3740c, Rv3734c, etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative triacylglycerol synthase
                     (diacylglycerol acyltransferase)"
                     /protein_id="AJF01570.1"
                     /db_xref="GOA:P96403"
                     /db_xref="InterPro:IPR004255"
                     /db_xref="InterPro:IPR009721"
                     /db_xref="InterPro:IPR014292"
                     /db_xref="UniProtKB/Swiss-Prot:P96403"
                     /translation="MKRLSGWDAVLLYSETPNVHMHTLKVAVIELDSDRQEFGVDAFR
                     EVIAGRLHKLEPLGYQLVDVPLKFHHPMWREHCQVDLNYHIRPWRLRAPGGRRELDEA
                     VGEIASTPLNRDHPLWEMYFVEGLANHRIAVVAKIHHALADGVASANMMARGMDLLPG
                     PEVGRYVPDPAPTKRQLLSAAFIDHLRHLGRIPATIRYTTQGLGRVRRSSRKLSPALT
                     MPFTPPPTFMNHRLTPERRFATATLALIDVKATAKLLGATINDMVLAMSTGALRTLLL
                     RYDGKAEPLLASVPVSYDFSPERISGNRFTGMLVALPADSDDPLQRVRVCHENAVSAK
                     ESHQLLGPELISRWAAYWPPAGAEALFRWLSERDGQNKVLNLNISNVPGPRERGRVGA
                     ALVTEIYSVGPLTAGSGLNITVWSYVDQLNISVLTDGSTVQDPHEVTAGMIADFIEIR
                     RAAGLSVELTVVESAMAQA"
     gene            265507..266295
                     /gene="echA1"
                     /locus_tag="Y980_0222"
     CDS             265507..266295
                     /gene="echA1"
                     /locus_tag="Y980_0222"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0222, (MTCY08D5.17) Probable echA1,enoyl-CoA
                     hydratase, similar to others e.g. AAC77915.1|AF063588
                     enoyl CoA hydratase from Rhodococcus fascians (275 aa);
                     etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative enoyl-CoA hydratase EchA1 (enoyl
                     hydrase) (unsaturated acyl-CoA hydratase) (crotonase)"
                     /protein_id="AJF01571.1"
                     /db_xref="GOA:L7N5S5"
                     /db_xref="InterPro:IPR001753"
                     /db_xref="InterPro:IPR014748"
                     /db_xref="InterPro:IPR018376"
                     /db_xref="UniProtKB/TrEMBL:L7N5S5"
                     /translation="MSSESDAANTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGL
                     ADAMDQLDGDAGLSVAILTGGGGSFCAGMDLKAFARGENVVVEGRGLGFTERPPTKPL
                     IAAVEGYALAGGTELALAADLIVAARDSAFGIPEVKRGLVAGGGGLLRLPERIPYAIA
                     MELALTGDNLPAERAHELGLVNVLAEPGTALDAAIALAEKITANGPLAVVATKRIITE
                     SRGWSPDTMFAEQMKILVPVFTSNDAKEGAIAFAERRRPRWTGT"
     gene            complement(266301..267764)
                     /locus_tag="Y980_0223c"
     CDS             complement(266301..267764)
                     /locus_tag="Y980_0223c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00070"
                     /inference="protein motif:PROSITE:PS00687"
                     /note="Rv0223c, (MTCY08D5.18) Probable aldehyde
                     dehydrogenase, similar to others e.g.
                     A75608|6460525|AAF12231.1|AE001862_57 aldehyde
                     dehydrogenase from Deinococcus radiodurans strain R1 (495
                     aa); Q47943 L-sorbosone dehydrogenase NAD(P) dependent
                     from Gluconobacter oxydans (498 aa); etc. Also similar to
                     Rv0768, Rv2858c, etc from Mycobacterium tuberculosis.
                     Contains PS00687 Aldehyde dehydrogenases glutamic acid
                     active site; and PS00070 Aldehyde dehydrogenases cysteine
                     active site. Belongs to the aldehyde dehydrogenases
                     family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aldehyde dehydrogenase"
                     /protein_id="AJF01572.1"
                     /db_xref="GOA:P96405"
                     /db_xref="InterPro:IPR015590"
                     /db_xref="InterPro:IPR016160"
                     /db_xref="InterPro:IPR016161"
                     /db_xref="InterPro:IPR016162"
                     /db_xref="InterPro:IPR016163"
                     /db_xref="PDB:3B4W"
                     /db_xref="UniProtKB/TrEMBL:P96405"
                     /translation="MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAA
                     AADVDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLFTKLLAAETGQPP
                     TIIETMHWMGSMGAMNYFAGAADKVTWTETRTGSYGQSIVSREPVGVVGAIVAWNVPL
                     FLAVNKIAPALLAGCTIVLKPAAETPLTANALAEVFAEVGLPEGVLSVVPGGIETGQA
                     LTSNPDIDMFTFTGSSAVGREVGRRAAEMLKPCTLELGGKSAAIILEDVDLAAAIPMM
                     VFSGVMNAGQGCVNQTRILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLISEK
                     QRTRVEGYIAKGIEEGARLVCGGGRPEGLDNGFFIQPTVFADVDNKMTIAQEEIFGPV
                     LAIIPYDTEEDAIAIANDSVYGLAGSVWTTDVPKGIKISQQIRTGTYGINWYAFDPGS
                     PFGGYKNSGIGRENGPEGVEHFTQQKSVLLPMGYTVA"
     gene            complement(267863..268627)
                     /locus_tag="Y980_0224c"
     CDS             complement(267863..268627)
                     /locus_tag="Y980_0224c"
                     /note="Rv0224c, (MTCY08D5.19c) Possible methyltransferase,
                     showing weak similarity with other methyltransferases e.g.
                     P74388 sterol-C-methyltransferase (318 aa). Equivalent to
                     AL022486|MLCB1883_1 from Mycobacterium leprae (269 aa).
                     Also some similarity with MTCY21B4.22c from Mycobacterium
                     tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="putative methyltransferase (methylase)"
                     /protein_id="AJF01573.1"
                     /db_xref="GOA:P96406"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="UniProtKB/Swiss-Prot:P96406"
                     /translation="MAVTDVFARRATLRRSLRLLADFRYEQRDPARFYRTLAADTAAM
                     IGDLWLATHSEPPVGRTLLDVGGGPGYFATAFSDAGVGYIGVEPDPDEMHAAGPAFTG
                     RPGMFVRASGMALPFADDSVDICLSSNVAEHVPRPWQLGTEMLRVTKPGGLVVLSYTV
                     WLGPFGGHEMGLSHYLGGARAAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGA
                     ALAVFPRYHPRWAWWLTSVPVLREFLVSNLVLVLTP"
     gene            268663..269817
                     /locus_tag="Y980_0225"
     CDS             268663..269817
                     /locus_tag="Y980_0225"
                     /note="Rv0225, (MTCY08D5.20) Possible conserved protein
                     involved in LPS biosynthesis, similar to O26275 LPS
                     biosynthesis RFBU related protein (382 aa). Some
                     similarity with Rv3032 from Mycobacterium tuberculosis.
                     Predicted to be an outer membrane protein (See Song et
                     al., 2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01574.1"
                     /db_xref="GOA:L7N515"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:L7N515"
                     /translation="MSALRSVLLLCWRDIGHPQGGGSEAYLQRIGAQLAASGIAVTLR
                     TARYPGAPRHELVDGVRISRAGGRYSVYLWALLAMAAARCGLGPLRRVRPDVVVDTQN
                     GWPFVARLLYGRRSLVLVHHCHREQWPVAGRMMGRLGWYVESMLSPRLHRRNQYVTVS
                     LPSARDLIALGVDSERIAVVRNGLDEAPSPTLSGPRAPTPRVVVLSRLVPHKQIEDAL
                     AAVAELQPRIPGLHLDIVGGGWWRQRLVDHVHRLDIADAVTFHGHVDDVTKHHVLQSS
                     WVHLLPSRKEGWGLAVIEAAQHGVPTIGYRSSGGLADSIVDGVTGILVDDRAELVAWL
                     EQLLSDSVLRDQLGAKAQARSGEFSWRQSAEALRSVLEAVQASRFVSGVV"
     gene            complement(269834..271564)
                     /locus_tag="Y980_0226c"
     CDS             complement(269834..271564)
                     /locus_tag="Y980_0226c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0226c, (MTCY08D5.21c) Probable conserved
                     transmembrane protein, equivalent, except in N-terminal
                     part, to AC32114.1|AL583926 conserved membrane protein
                     from Mycobacterium leprae (600 aa). Also similar to
                     AL021411|SC7H1_20 from Streptomyces coelicolor (483 aa). A
                     core mycobacterial gene; conserved in mycobacterial
                     strains (See Marmiesse et al.,2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01575.1"
                     /db_xref="GOA:L7N5S8"
                     /db_xref="UniProtKB/TrEMBL:L7N5S8"
                     /translation="MRWFRPGYALVLVLLLAAPLLRPGYLLLRDAVSTPRSYVSANAL
                     GLTSAPRATPQDFAVALASHLVDGGVVVKALLLLGLWLAGWGAARLVATALPAAGAAG
                     QFVAITLAIWNPYVAERLLQGHWSLLVGYGCLPWVATAMLTMRTTVGAGWFGLFGLAF
                     WVALAGLTPSGLLLAATVAVVCVAMPGAGRPRWQCGVAALGSALVGALPWLTASALGS
                     SLTSHTAANQLGVTAFAPRAEPGLGTLGSLASLGGIWNGEAVPSSRTTLFAVASAVVL
                     LAMVAIGLPTVARRPVAVPLLTLAAVSVMVPAVLATGPGLHALRVVVDAAPGLGVLRD
                     GQKWVALAVPGYTLSGAGTVLTLRRWLRPATAAVVCCLALVLTLPDLAWGVWGKVAPV
                     HYPSGWAAVAAAINADPRTVAVLPAGTMRRFSWSGSAPVLDPLPRWVRADVLTTGDLV
                     ISGVTVPGEDAHARAVQELLLTGPHPSTLAAAGVGWLVVESDSAGDMGAAARTLGRLA
                     AAHRDDELALYRVGGQTSGASSARLKATMLAHWAWLSMLLVGGAGAAGYWVRRHLHHC
                     EDTPASRAQD"
     gene            complement(271574..272839)
                     /locus_tag="Y980_0227c"
     CDS             complement(271574..272839)
                     /locus_tag="Y980_0227c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0227c, (MTCY08D5.22c) Possible conserved membrane
                     protein, equivalent to AL022486|MLCB1883_4 from
                     Mycobacterium leprae (448 aa). A core mycobacterial gene;
                     conserved in mycobacterial strains (See Marmiesse et al.,
                     2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved membrane protein"
                     /protein_id="AJF01576.1"
                     /db_xref="InterPro:IPR021424"
                     /db_xref="UniProtKB/TrEMBL:L7N4X8"
                     /translation="MLRFAACGAIGLGAALLIAALLLSTYTTSRIAEIPLDIDATLIS
                     DGTGTALDSASLATEHIVVNQDVPLVSQQQVTVESPANADVVTLQVGSSLRRTDKQKD
                     SGLLLAIVDTVTLNRKTAMAVSDDTHTGGAVQKPRGLNDENPPTAIPLRHDGLSYRFP
                     FHTEKKTYPYFDPIAQKAFDANYEGEEDVNGLTTYRFTQNVGYTPEGKLVAPLKYPSL
                     YAGDEDGKVTTSAAMWGLPGDPNEQITMTRYYAAQRTFWVDPVSGTIVKETERANHYF
                     ARDPLKPEVTFADYQVTSTEETVESQVNAARDERDRLALWSRVLPITFTAAGLVALVG
                     GGLFASFSLRTEGALMAASGDRDDHDYRRGGFEEPVPGAEAETEKLPTQRPDFPREPS
                     GSDPPRLGSAQPPPPPDAGHPDPGPPERR"
     repeat_region   complement(272855..272955)
                     /note="101 bp Mycobacterial Interspersed Repetitive
                     Unit,class III"
     gene            273055..274278
                     /locus_tag="Y980_0228"
     CDS             273055..274278
                     /locus_tag="Y980_0228"
                     /note="Rv0228, (MTCY08D5.23) Probable integral membrane
                     acyltransferase, equivalent to
                     3063875|CAA18555.1|AL022486|T44870 acyltransferase from
                     Mycobacterium leprae (384 aa). Also similar to others e.g.
                     Q11064 probable acyltransferase CY50.28C (383 aa);
                     Q00718|MDMB_STRMY acyltransferase. Very similar to Rv0111,
                     Rv1254, etc from Mycobacterium tuberculosis."
                     /codon_start=1
                     /transl_table=11
                     /product="putative integral membrane acyltransferase"
                     /protein_id="AJF01577.1"
                     /db_xref="GOA:L0T619"
                     /db_xref="InterPro:IPR002656"
                     /db_xref="UniProtKB/TrEMBL:L0T619"
                     /translation="MGPADESGAPIRPQTPHRHTVLVTNGQVVGGTRGFLPAVEGMRA
                     CAAVGVVVTHVAFQTGHSSGVGGRLFGRFDLAVAVFFAVSGFLLWRGHAAAARDLRSH
                     PRTGPYLRSRVARIMPAYVVAVVVILSLLPDADHASLTVWLANLTLTQIYVPLTLTGG
                     LTQMWSLSVEVAFYAALPVLALLGRRIPVGARVPAIAALAALSWAWGWLPLDAGSGIN
                     PLTWPPAFFSWFAAGMLLAEWAYSPVGLPHRWARRRVAMAVTALLGYLVAASPLAGPE
                     GLVPGTAAQFAVKTAMGSLVAFALVAPLVLDRPDTSHRLLGSPAMVTLGRWSYGLFIW
                     HLAALAMVFPVIGAFPFTGRMPTVLVLTLIFGFAIAAVSYALVESPCREALRRWERRN
                     EPISVGELQADAIAP"
     gene            complement(274306..274986)
                     /locus_tag="Y980_0229c"
     CDS             complement(274306..274986)
                     /locus_tag="Y980_0229c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00626"
                     /note="Rv0229c, (MTCY08D5.24c) Possible conserved membrane
                     protein with PIN domain in C-terminal half, similar to
                     several others from Mycobacterium tuberculosis. Has some
                     similarity with Rv2757c|D70880 from Mycobacterium
                     tuberculosis (138 aa, see Arcus et al.,2005), and Rv0301,
                     Rv2546, etc. Also some similarity with Q48177 virulence
                     associated protein C (132 aa). Contains PS00626 Regulator
                     of chromosome condensation (RCC1) signature 2."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved membrane protein with PIN
                     domain"
                     /protein_id="AJF01578.1"
                     /db_xref="GOA:L7N5I6"
                     /db_xref="InterPro:IPR002716"
                     /db_xref="InterPro:IPR022907"
                     /db_xref="UniProtKB/TrEMBL:L7N5I6"
                     /translation="MRQPRRANAMGLALCIYIGSLLIYTPIHGETSRRHRRAGFKHGS
                     YRIGHDDDQRHRQRGPAASHVSASSTRRRRSRHAGRRTARGPRRSMALKYLLDTSVIK
                     RLSRPAVRRAVEPLAEAGAVARTQITDLEVGYSARNETEWQRLMVALSAFDLIESTAS
                     HHRRALGIQRLLAARSQRGRKIPDLLIAAAGEEHGLVVLHYDADFDLIAAVTGQPCQW
                     IVPAGTID"
     gene            complement(274983..275963)
                     /gene="php"
                     /locus_tag="Y980_0230c"
     CDS             complement(274983..275963)
                     /gene="php"
                     /locus_tag="Y980_0230c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0230c, (MTCY08D5.26c) Probable
                     php,phosphotriesterase, similar to others e.g.
                     AAK42653.1|AE006849 putative aryldialkylphosphatase
                     (phosphotriesterase) (paraoxonase) from Sulfolobus
                     solfataricus (314 aa); PHP_ECOLI|P45548 phosphotriesterase
                     homology protein from Escherichia coli (292 aa);
                     OPD_FLASP|P16648 parathion hydrolase precursor (365 aa);
                     etc. Belongs to the phosphotriesterase family. Cofactor:
                     contains 2 moles of zinc per subunit."
                     /codon_start=1
                     /transl_table=11
                     /product="putative phosphotriesterase Php (parathion
                     hydrolase) (PTE) (aryldialkylphosphatase) (paraoxonase)
                     (a-esterase) (aryltriphosphatase) (paraoxon hydrolase)"
                     /protein_id="AJF01579.1"
                     /db_xref="GOA:P96413"
                     /db_xref="InterPro:IPR001559"
                     /db_xref="InterPro:IPR017947"
                     /db_xref="UniProtKB/Swiss-Prot:P96413"
                     /translation="MPELNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDED
                     KRVAGAIARLGELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLYTYND
                     VPFYFHYLGPGAQLDGPEIMTDMFVRDIEHGIADTGIKAGILKCATDEPGLTPGVERV
                     LRAVAQAHKRTGAPISTHTHAGLRRGLDQQRIFAEEGVDLSRVVIGHCGDSTDVGYLE
                     ELIAAGSYLGMDRFGVDVISPFQDRVNIVARMCERGHADKMVLSHDACCYFDALPEEL
                     VPVAMPNWHYLHIHNDVIPALKQHGVTDEQLHTMLVDNPRRIFERQGGYQ"
     gene            276058..277764
                     /gene="fadE4"
                     /locus_tag="Y980_0231"
     CDS             276058..277764
                     /gene="fadE4"
                     /locus_tag="Y980_0231"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0231, (MTCY08D5.27) Probable fadE4,acyl-CoA
                     dehydrogenase, similar to many e.g. O29752 acyl-CoA
                     dehydrogenase (ACD-3) from Archaeoglobus fulgidus (576
                     aa); ACDB_BACSU|P45857 acyl-CoA dehydrogenase from
                     Bacillus subtilis (379 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA dehydrogenase FadE4"
                     /protein_id="AJF01580.1"
                     /db_xref="GOA:L7N634"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="UniProtKB/TrEMBL:L7N634"
                     /translation="MLLNPNHLTRKYPDRRSGEIMAATVDFFESRGKARLKHDDHERI
                     WYSDFLDFVGRERIFASLLTPASYGADDCRWDTYRISEFAEIMGFYGLSYWYPFQVTA
                     LGLGPIWMSANEDAKRKAAAGLEAGEVFAFGLSEQTHGADVYQTDMILTPSDGGWTAN
                     GEKYYIGNANVARMVSTFGKIAGTPESQEYVFFVADSQHERYDLIKNVVNSQNYVANY
                     ALRDYPVTEADILHRGAEAFHAALNTVNVCKYNLGWGAIGMCTHALYESVTHAANRHL
                     YGTVVTDFSHVRRLLTDAYVRLIAMKLVASRASDYMRSASAADRRYLLYSPLTKAKVT
                     SEGERVITALWDVIAAKGVEKDTFFETVAREIGLLPRLEGTVHINIGLLGKFMPNYLF
                     APDSTLPVIPRRDDAADDAFLFAQGPTGGLGKVRFHDWRASFDTCAHLPNVALLREQV
                     DVFAELLASATPDAAQQKDIDFAFGVGQLFANVPYAQLILEEARLSGVDEALIDEIFG
                     VLVRDFNTHAVELHGRSATTAEQARFAMRMVRRPVHDPARYDQIWKDHVLALNGAYQM
                     AP"
     gene            277899..278588
                     /locus_tag="Y980_0232"
     CDS             277899..278588
                     /locus_tag="Y980_0232"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS01081"
                     /note="Rv0232, (MTCY08D5.28) Probable transcriptional
                     regulatory protein, TetR/AcrR family,similar to others
                     e.g. YIXD_BACSU|P32398 hypothetical transcriptional
                     regulator (191 aa). Also similar to MTV030_11 from
                     Mycobacterium tuberculosis. Contains PS01081 Bacterial
                     regulatory proteins, TetR family signature, and probable
                     helix-turn helix motif from aa 33-54 (Score 1142, +3.08
                     SD). Belongs to the TetR/AcrR family of transcriptional
                     regulators."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein
                     (probably TetR/AcrR-family)"
                     /protein_id="AJF01581.1"
                     /db_xref="GOA:L7N4D1"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="InterPro:IPR023772"
                     /db_xref="UniProtKB/TrEMBL:L7N4D1"
                     /translation="MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNVIARRAGV
                     AKGSLFQYFADKRDLYAFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDLLDGWVAY
                     FAEHPRERALHAAATLEVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTG
                     ALMSLLLLIFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPAT
                     NSAQTRSEEIT"
     gene            278585..279529
                     /gene="nrdB"
                     /locus_tag="Y980_0233"
                     /gene_synonym="rnrS"
     CDS             278585..279529
                     /gene="nrdB"
                     /locus_tag="Y980_0233"
                     /gene_synonym="rnrS"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0233, (MTCY08D5.29) nrdB (alternate gene name:
                     rnrS) ribonucleoside-diphosphate reductase, beta chain,
                     similar to others e.g. RIR2_SCHPO|P36603
                     ribonucleoside-diphosphate reductase (391 aa); etc.
                     Belongs to the ribonucleoside diphosphate reductase small
                     chain family. Cofactor: iron, manganese"
                     /codon_start=1
                     /transl_table=11
                     /product="Ribonucleoside-diphosphate reductase (beta
                     chain) NrdB (ribonucleotide reductase small chain)"
                     /protein_id="AJF01582.1"
                     /db_xref="GOA:P96416"
                     /db_xref="InterPro:IPR000358"
                     /db_xref="InterPro:IPR009078"
                     /db_xref="InterPro:IPR012348"
                     /db_xref="PDB:3EE4"
                     /db_xref="PDB:4AC8"
                     /db_xref="UniProtKB/Swiss-Prot:P96416"
                     /translation="MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWHPADIDFTRDRA
                     DWEKLSDDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFEEA
                     KHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADPSPAAQVRASV
                     TYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGDDERRHMAWGTFTCRRHVA
                     ADDANWTVFETRMNELIPLALRLIEEGFALYGDQPPFDLSKDDFLQYSTDKGMRRFGT
                     ISNARGRPVAEIDVDYSPAQLEDTFADEDRRTLAAASA"
     gene            complement(279605..281140)
                     /gene="gabD1"
                     /locus_tag="Y980_0234c"
                     /gene_synonym="gabD2"
     CDS             complement(279605..281140)
                     /gene="gabD1"
                     /locus_tag="Y980_0234c"
                     /gene_synonym="gabD2"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00070"
                     /note="Rv0234c, (MTCY08D5.30c)
                     gabD1,succinate-semialdehyde dehydrogenase [NADP+]
                     dependent,equivalent to AL022486|MLCB1883_6 probable
                     aldehyde dehydrogenase from Mycobacterium leprae (457 aa).
                     Also highly similar to Q55585|GABD|SLR0370 probable
                     succinate-semialdehyde dehydrogenase from Synechocystis
                     sp. strain PCC 6803 (454 aa); and similar to others e.g.
                     GABD_ECOLI|P25526 succinate-semialdehyde dehydrogenase
                     from Escherichia coli (482 aa); etc. Note that similar to
                     other cytosolic aldehyde dehydrogenases with EC number:
                     1.2.1.3. Also similar to Rv0768|aldA semialdehyde
                     dehydrogenase from Mycobacterium tuberculosis (489 aa);
                     and gabD2|Rv1731|MTCY04C12.16 possible
                     succinate-semialdehyde dehydrogenase [NADP+] dependent
                     from Mycobacterium tuberculosis (518 aa). Contains PS00070
                     aldehyde dehydrogenases cysteine active site. Belongs to
                     the aldehyde dehydrogenases family. Could start at
                     different site by homology. Note that previously known as
                     gabD2."
                     /codon_start=1
                     /transl_table=11
                     /product="Succinate-semialdehyde dehydrogenase [NADP+]
                     dependent (SSDH) GabD1"
                     /protein_id="AJF01583.1"
                     /db_xref="GOA:P71989"
                     /db_xref="InterPro:IPR015590"
                     /db_xref="InterPro:IPR016160"
                     /db_xref="InterPro:IPR016161"
                     /db_xref="InterPro:IPR016162"
                     /db_xref="InterPro:IPR016163"
                     /db_xref="UniProtKB/Swiss-Prot:P71989"
                     /translation="MRSVTCSATLVLPVIEPTPADRRPRHLLLGSAGHVSGRLDTGRF
                     VQTHPAKDVSVPIATINPATGETVKTFTAATDDEVDAAIARAHRRFADYRQTSFAQRA
                     RWANATADLLEAEADQAAAMMTLEMGKTLAAAKAEALKCAKGFRYYAENAEALLADEP
                     ADAAKVGASAAYGRYQPLGVILAVMPWNFPLWQAVRFAAPALMAGNVGLLKHASNVPQ
                     CALYLADVIARGGFPDGCFQTLLVSSGAVEAILRDPRVAAATLTGSEPAGQSVGAIAG
                     NEIKPTVLELGGSDPFIVMPSADLDAAVSTAVTGRVQNNGQSCIAAKRFIVHADIYDD
                     FVDKFVARMAALRVGDPTDPDTDVGPLATEQGRNEVAKQVEDAAAAGAVIRCGGKRLD
                     RPGWFYPPTVITDISKDMALYTEEVFGPVASVFRAANIDEAVEIANATTFGLGSNAWT
                     RDETEQRRFIDDIVAGQVFINGMTVSYPELPFGGVKRSGYGRELSAHGIREFCNIKTV
                     WIA"
     gene            complement(281166..282614)
                     /locus_tag="Y980_0235c"
     CDS             complement(281166..282614)
                     /locus_tag="Y980_0235c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0235c, (MTCY08D5.31c) Probable conserved
                     transmembrane protein, highly similar to
                     AL133278|CAB61913.1|SCM11_2 putative integral membrane
                     protein from Streptomyces coelicolor (470 aa); and similar
                     to hypothetical proteins from other organisms e.g.
                     Q13392|384D8_7 hypothetical protein (579 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved transmembrane protein"
                     /protein_id="AJF01584.1"
                     /db_xref="GOA:L7N4E1"
                     /db_xref="InterPro:IPR009613"
                     /db_xref="UniProtKB/TrEMBL:L7N4E1"
                     /translation="MGWFSAPEYWLGRLALERGTAIIYLIAFVAAAQQFRPLIGEHGM
                     LPVPRYLAGQSFWRTPSIFHFRYSDRVFAGVCWLGAVLSAAVVAGAASFVPLWATMLI
                     WLTLWVLYLSIVNVGQAWYSFGWESLLLETGFLMIFLGNERTAPPILTLLLARWLLFR
                     VEFGAGLIKMRGDSCWRSLTCLYYHHETQPMPGPLSWFFHHLPKPLHRIEVAGNHFAQ
                     LVVPFGLFTPQPAASIAAAIIVVTQLWLVASGNFSWLNWLTILLACSAIDTSSAAALL
                     PMPAQPALSAPPQWFAGLVVVFTAAVLLLSYWPARNLLSSHQRMNMSFNPFHLVNTYG
                     AFGSICRTRREVVIEGTDESPITEQTVWKAYEFKGKPGDPRRLPRQWAPYHLRLDWLM
                     WFAAISPGYALPWMTPFLNRLLRNDPATLKLLRHNPFPQSPPRYVRAQLYQYRFTTVA
                     ELRRDRAWWHRTLIGRYVPPMSLRKVASPPAD"
     gene            complement(282649..286851)
                     /gene="aftD"
                     /locus_tag="Y980_0236c"
     CDS             complement(282649..286851)
                     /gene="aftD"
                     /locus_tag="Y980_0236c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0236c, (MTV034.01c, MTV034.02c,
                     MTCY08D5.32c),len: 1400 aa. Possible aftD,
                     arabinofuranosyltransferase (See Skovierova et al., 2009).
                     Predicted to be in the GT-C superfamily of
                     glycosyltransferases (See Liu and Mushegian,2003).
                     Probable conserved transmembrane protein, equivalent to
                     AL022486|CAC32102.1|MLCB1883_7 possible integral membrane
                     protein from Mycobacterium leprae (1440 aa). A core
                     mycobacterial gene; conserved in mycobacterial strains
                     (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative arabinofuranosyltransferase AftD"
                     /protein_id="AJF01585.1"
                     /db_xref="GOA:P96419"
                     /db_xref="InterPro:IPR000421"
                     /db_xref="InterPro:IPR008979"
                     /db_xref="InterPro:IPR021798"
                     /db_xref="UniProtKB/Swiss-Prot:P96419"
                     /translation="MAPLSRKWLPVVGAVALALTFAQSPGQVSPDTKLDLTANPLRFL
                     ARATNLWNSDLPFGQAQNQAYGYLFPHGTFFVIGHLLGVPGWVTQRLWWAVLLTVGFW
                     GLLRVAEALGVGGPSSRVVGAVAFALSPRVLTTLGSISSETLPMMLAPWVLLPTILAL
                     RGTSGRSVRALAAQAGLAVALMGAVNAIATLAGCLPAVIWWACHRPNRLWWRYTAWWL
                     LAMALATLWWVMALTQLHGVSPPFLDFIESSGVTTQWSSLVEVLRGTDSWTPFVAPNA
                     TAGAPLVTGSAAILGTCLVAAAGLAGLTSPAMPARGRLVTMLLVGVVLLAVGHRGGLA
                     SPVAHPVQAFLDAAGTPLRNVHKVGPVIRLPLVLGLAQLLSRVPLPGSAPRPAWLRAF
                     AHPERDKRVAVAVVALTALMVSTSLAWTGRVAPPGTFGALPQYWQEAADWLRTHHAAT
                     PTPGRVLVVPGAPFATQVWGTSHDEPLQVLGDGPWGVRDSIPLTPPQTIRALDSVQRL
                     FAAGRPSAGLADTLARQGISYVLVRNDLDPETSRSARPILLHRSIAGSPGLAKLAEFG
                     APVGPDPLAGFVNDSGLRPRYPAIEIYRVSAPANPGAPYFAATDQLARVDGGPEVLLR
                     LDERRRLQGQPPLGPVLMTADARAAGLPVPQVAVTDTPVARETDYGRVDHHSSAIRAP
                     GDARHTYNRVPDYPVPGAEPVVGGWTGGRITVSSSSADATAMPDVAPASAPAAAVDGD
                     PATAWVSNALQAAVGQWLQVDFDRPVTNAVVTLTPSATAVGAQVRRILIETVNGSTTL
                     RFDEAGKPLTAALPYGETPWVRFTAAATDDGSAGVQFGITDLAITQYDASGFAHPVQL
                     RHTVLVPGPPPGSAIAGWDLGSELLGRPGCAPGPDGVRCAASMALAPEEPANLSRTLT
                     VPRPVSVTPMVWVRPRQGPKLADLIAAPSTTRASGDSDLVDILGSAYAAADGDPATAW
                     TAPQRVVQHKTPPTLTLTLPRPTVVTGLRLAASRSMLPAHPTVVAINLGDGPQVRQLQ
                     VGELTTLWLHPRVTDTVSVSLLDWDDVIDRNALGFDQLKPPGLAEVVVLSAGGAPIAP
                     ADAARNRARALTVDCDHGPVVAVAGRFVHTSIRTTVGALLDGEPVAALPCEREPIALP
                     AGQQELLISPGAAFVVDGAQLSTPGAGLSSATVTSAETGAWGPTHREVRVPESATSRV
                     LVVPESINSGWVARTSTGARLTPIAVNGWQQAWVVPAGNPGTITLTFAPNSLYRASLA
                     IGLALLPLLALLAFWRTGRRQLADRPTPPWRPGAWAAAGVLAAGAVIASIAGVMVMGT
                     ALGVRYALRRRERLRDRVTVGLAAGGLILAGAALSRHPWRSVDGYAGNWASVQLLALI
                     SVSVVAASVVATSESRGQDRMQ"
     gene            complement(286898..287071)
                     /locus_tag="Y980_0236A"
     CDS             complement(286898..287071)
                     /locus_tag="Y980_0236A"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0236A Small secreted protein. A core
                     mycobacterial gene; conserved in mycobacterial strains
                     (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="Small secreted protein"
                     /protein_id="AJF01586.1"
                     /db_xref="InterPro:IPR022566"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5C5"
                     /translation="MNRIVAPAAASVVVGLLLGAAAIFGVTLMVQQDKKPPLPGGDPS
                     SSVLNRVEYGNRS"
     gene            287186..288352
                     /gene="lpqI"
                     /locus_tag="Y980_0237"
     CDS             287186..288352
                     /gene="lpqI"
                     /locus_tag="Y980_0237"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00013"
                     /note="Rv0237, (MTV034.03) Probable lpQI,conserved
                     lipoprotein, equivalent to AL022486|MLCB1883_8|T44873
                     probable secreted hydrolase from Mycobacterium leprae (387
                     aa). Also similar to other lipoproteins and various
                     hydrolases e.g. P40406|2126897|YBBD_BACSU|I39839
                     hypothetical 70.6 KDA lipoprotein from Bacillus subtilis
                     (642 aa); P48823|HEXA_ALTSO beta-hexosaminidase a
                     precursor from alteromonas SP. (598 aa); PCC6803|P74340
                     beta-glucosidase from Synechocystis sp. (538 aa). Contains
                     signal sequence and appropriately positioned PS00013
                     Prokaryotic membrane lipoprotein lipid attachment site."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved lipoprotein LpqI"
                     /protein_id="AJF01587.1"
                     /db_xref="GOA:Q7DA74"
                     /db_xref="InterPro:IPR001764"
                     /db_xref="InterPro:IPR017853"
                     /db_xref="UniProtKB/TrEMBL:Q7DA74"
                     /translation="MAFPRTLAILAAAAALVVACSHGGTPTGSSTTSGASPATPVAVP
                     VPRSCAEPAGIPALLSPRDKLAQLLVVGVRDAADAQAVVTNYHVGGILIGSDTDLTIF
                     DGALAEIVAGGGPLPLAVSVDEEGGRVSRLRSLIGGTGPSARELAQTRTVQQVRDLAR
                     DRGRQMRKLGITIDFAPVVDVTDAPDDTVIGDRSFGSDPATVTAYAGAYAQGLRDAGV
                     LPVLKHFPGHGRGSGDSHNGGVTTPPLDDLVGDDLVPYRTLVTQAPVGVMVGHLQVPG
                     LTGSEPASLSKAAVNLLRTGTGYGAPPFDGPVFSDDLSGMAAISDRFGVSEAVLRTLQ
                     AGADIALWVTTKEVPAVLDRLEQALRAGELPMSAVDRSVVRVATMKGPNPGCGR"
     gene            288428..289042
                     /locus_tag="Y980_0238"
     CDS             288428..289042
                     /locus_tag="Y980_0238"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0238, (MTV034.04) Possible transcriptional
                     regulatory protein, TetR family, equivalent to
                     AL022486|MLCB1883_9|T44874 probable transcription
                     regulator from Mycobacterium leprae (208 aa). Also similar
                     to others e.g. CAB77290.1|AL160312 putative TetR-family
                     regulatory protein from Streptomyces coelicolor (240 aa).
                     Also similar to Mycobacterium tuberculosis proteins
                     Z95120|Rv3208 (228 aa); and Rv1019 (197 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein
                     (probably TetR-family)"
                     /protein_id="AJF01588.1"
                     /db_xref="GOA:L7N4P6"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:L7N4P6"
                     /translation="MAGGTKRLPRAVREQQMLDAAVQMFSVNGYHETSMDAIAAEAQI
                     SKPMLYLYYGSKEDLFGACLNREMSRFIDALRSSINFDQSPKDLLRNTIVSFLRYIDA
                     NRASWIVMYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEMMAVALV
                     GAGEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVDRLETGH"
     gene            289104..289337
                     /gene="vapB24"
                     /locus_tag="Y980_0239"
     CDS             289104..289337
                     /gene="vapB24"
                     /locus_tag="Y980_0239"
                     /note="Rv0239, (MTV034.05) Possible vapB24,antitoxin, part
                     of toxin-antitoxin (TA) operon with Rv0240. Weakly similar
                     to others e.g. Rv1839c|Z83859|MTCY359_34 from
                     Mycobacterium tuberculosis (87 aa), see Arcus et al.
                     2005."
                     /codon_start=1
                     /transl_table=11
                     /product="putative antitoxin VapB24"
                     /protein_id="AJF01589.1"
                     /db_xref="UniProtKB/Swiss-Prot:O53662"
                     /translation="MIRTQVQLPDELYRDAKRVAHEHEMTLAEVVRRGLEHMVRIYPR
                     RDAASDTWQPPTPRRLGPFRASEETWRELANEA"
     gene            289345..289782
                     /gene="vapC24"
                     /locus_tag="Y980_0240"
     CDS             289345..289782
                     /gene="vapC24"
                     /locus_tag="Y980_0240"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0240, (MTV034.06) Possible vapC24,toxin, part of
                     toxin-antitoxin (TA) operon with Rv0239,contains PIN
                     domain, weak similarity with Rv3697c from Mycobacterium
                     tuberculosis (145 aa), see Arcus et al. 2005."
                     /codon_start=1
                     /transl_table=11
                     /product="putative toxin VapC24, contains PIN domain"
                     /protein_id="AJF01590.1"
                     /db_xref="GOA:O53663"
                     /db_xref="InterPro:IPR002716"
                     /db_xref="InterPro:IPR006226"
                     /db_xref="InterPro:IPR022907"
                     /db_xref="UniProtKB/Swiss-Prot:O53663"
                     /translation="MLSIDTNILLYAQNRDCPEHDAAAAFLVECAGRADVAVCELVLM
                     ELYQLLRNPTVVTRPLEGPEAAEVCQTFRRNRRWALLENAPVMNEVWVLAATPRIARR
                     RLFDARLALTLRHHGVDEFATRNINGFTDFGFSRVWDPITSDG"
     gene            complement(289812..290654)
                     /gene="htdX"
                     /locus_tag="Y980_0241c"
     CDS             complement(289812..290654)
                     /gene="htdX"
                     /locus_tag="Y980_0241c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0241c, (MTV034.07c) Probable
                     htdX,3-hydroxyacyl-thioester dehydratase (See Gurvitz et
                     al.,2009), highly similar to
                     MLCB1883.17c|T44876063881|CAA18566.1|AL022486 hypothetical
                     protein from Mycobacterium leprae (280 aa); and
                     CAC32097.1|AL583926 conserved hypothetical protein from
                     Mycobacterium leprae (300 aa). Shows structural similarity
                     to six others in Mycobacterium tuberculosis (see Castell
                     et al (2005) below). Also similar to proteins from other
                     organisms e.g. CAB77291.1|AL160312 putative dehydratase
                     from Streptomyces coelicolor (291 aa); part of
                     BAA92930.1|AB032743 fatty acid synthetase beta subunit
                     from Pichia angusta (2060 aa). Predicted to be an outer
                     membrane protein (See Song et al., 2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 3-hydroxyacyl-thioester dehydratase
                     HtdX"
                     /protein_id="AJF01591.1"
                     /db_xref="GOA:L7N5I2"
                     /db_xref="InterPro:IPR002539"
                     /db_xref="InterPro:IPR003965"
                     /db_xref="UniProtKB/TrEMBL:L7N5I2"
                     /translation="MTQPSGLKNLLRAAAGALPVVPRTDQLPNRTVTVEELPIDPANV
                     AAYAAVTGLRYGNQVPLTYPFALTFPSVMSLVTGFDFPFAAMGAIHTENHITQYRPIA
                     VTDAVGVRVRAENLREHRRGLLVDLVTNVSVGNDVAWHQVTTFLHQQRTSLSGEPKPP
                     PQKKPKLPPPAAVLRITPAKIRRYAAVGGDHNPIHTNPIAAKLFGFPTVIAHGMFTAA
                     AVLANIEARFPDAVRYSVRFAKPVLLPATAGLYVAEGDGGWDLTLRNMAKGYPHLTAT
                     VRGL"
     gene            complement(290665..292029)
                     /gene="fabG4"
                     /locus_tag="Y980_0242c"
     CDS             complement(290665..292029)
                     /gene="fabG4"
                     /locus_tag="Y980_0242c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00061"
                     /note="Rv0242c, (MTV034.08c) Probable
                     fabG4,3-oxoacyl-[acyl-carrier protein] reductase,
                     equivalent to
                     3063883|CAA18568.1|AL022486|MLCB1883_13|T44878
                     3-oxoacyl-[acyl-carrier protein] reductase homolog from
                     Mycobacterium leprae (454 aa). C-terminal part highly
                     similar to many FabG proteins e.g. U39441|VHU3944 1_2 from
                     Vibrio harveyi (244 aa); U91631|PAU91631_3 from
                     Pseudomonas aeruginosa (247 aa). Has N-terminal extension
                     of ~200 aa and C-terminal part contains PS00061
                     Short-chain dehydrogenases/reductases family signature.
                     Belongs to the short-chain dehydrogenases/reductases (SDR)
                     family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 3-oxoacyl-[acyl-carrier protein]
                     reductase FabG4 (3-ketoacyl-acyl carrier protein
                     reductase)"
                     /protein_id="AJF01592.1"
                     /db_xref="GOA:O53665"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="PDB:3M1L"
                     /db_xref="PDB:3Q6I"
                     /db_xref="PDB:3V1T"
                     /db_xref="PDB:3V1U"
                     /db_xref="PDB:4FW8"
                     /db_xref="UniProtKB/TrEMBL:O53665"
                     /translation="MAPKRSSDLFSQVVNSGPGSFLARQLGVPQPETLRRYRAGEPPL
                     TGSLLIGGAGRVVEPLRAALEKDYDLVGNNLGGRWADSFGGLVFDATGITEPAGLKGL
                     HEFFTPVLRNLGRCGRVVVVGGTPEAAASTNERIAQRALEGFTRSLGKELRRGATTAL
                     VYLSPDAKPAATGLESTMRFLLSAKSAYVDGQVFSVGADDSTPPADWEKPLDGKVAIV
                     TGAARGIGATIAEVFARDGAHVVAIDVESAAENLAETASKVGGTALWLDVTADDAVDK
                     ISEHLRDHHGGKADILVNNAGITRDKLLANMDDARWDAVLAVNLLAPLRLTEGLVGNG
                     SIGEGGRVIGLSSIAGIAGNRGQTNYATTKAGMIGITQALAPGLAAKGITINAVAPGF
                     IETQMTAAIPLATREVGRRLNSLLQGGQPVDVAEAIAYFASPASNAVTGNVIRVCGQA
                     MIGA"
     gene            292171..293493
                     /gene="fadA2"
                     /locus_tag="Y980_0243"
     CDS             292171..293493
                     /gene="fadA2"
                     /locus_tag="Y980_0243"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00099"
                     /note="Rv0243, (MTV034.09) Probable fadA2,acetyl-CoA
                     acyltransferase (3-acyl-CoA thiolase),equivalent, but
                     shorter 17 aa, to AL022486|MLCB1883_14T44879
                     acetyltransferase from Mycobacterium leprae (457 aa). Also
                     highly similar to many e.g. G83046|PA478 probable acyl-CoA
                     thiolase from Pseudomonas aeruginosa (425 aa);
                     AB77293.1|AL160312 putative ketoacyl CoA thiolase from
                     Streptomyces coelicolor (428 aa);
                     P76503|7449731|YFCY_ECOLI|D65007|B2342 probable
                     3-ketoacyl-CoA thiolase (acetyl-CoA acyltransferase)
                     (beta-ketothiolase) from Escherichia coli strain K-12 (436
                     aa); P55084|ECHB_HUMAN mitochondrial trifunctonal enzyme
                     (474 aa). Contains PS00099 Thiolases active site. Belongs
                     to the thiolase family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl-CoA acyltransferase FadA2
                     (3-ketoacyl-CoA thiolase) (beta-ketothiolase)"
                     /protein_id="AJF01593.1"
                     /db_xref="GOA:L7N5J4"
                     /db_xref="HSSP:P27796"
                     /db_xref="InterPro:IPR002155"
                     /db_xref="InterPro:IPR016038"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR020610"
                     /db_xref="InterPro:IPR020616"
                     /db_xref="InterPro:IPR020617"
                     /db_xref="UniProtKB/TrEMBL:L7N5J4"
                     /translation="MAPAAKNTSQTRRRVAVLGGNRIPFARSDGAYADASNQDMFTAA
                     LSGLVDRFGLAGERLDMVVGGAVLKHSRDFNLMRECVLGSELSPYTPAFDLQQACGTG
                     LQAAIAAADGIAAGRYEVAAAGGVDTTSDPPIGLGDDLRRTLLKLRRSRSNVQRLKLV
                     GTLPASLGVEIPANSEPRTGLSMGEHAAVTAKQMGIKRVDQDELAAASHRNMADAYDR
                     GFFDDLVSPFLGLYRDDNLRPNSSVEKLATLRPVFGVKAGDATMTAGNSTPLTDGASV
                     ALLASEQWAEAHSLAPLAYLVDAETAAVDYVNGNDGLLMAPTYAVPRLLARNGLSLQD
                     FDFYEIHEAFASVVLAHLAAWESEEYCKRRLGLDAALGSIDRSKLNVNGSSLAAGHPF
                     AATGGRILAQTAKQLAEKKAAKKGGGPLRGLISICAAGGQGVAAILEA"
     gene            293604..293705
                     /gene="F6"
                     /locus_tag="Y980_nc008"
                     /gene_synonym="mcr14"
                     /gene_synonym="mpr13"
     ncRNA           293604..293705
                     /ncRNA_class="other"
                     /gene="F6"
                     /locus_tag="Y980_nc008"
                     /gene_synonym="mcr14"
                     /gene_synonym="mpr13"
                     /product="Putative small regulatory RNA"
                     /note="F6, putative small regulatory RNA (See Arnvig and
                     Young, 2009; DiChiara et al., 2010). Alternate 3'-ends at
                     positions 293641 and 293661."
     gene            complement(293798..295633)
                     /gene="fadE5"
                     /locus_tag="Y980_0244c"
     CDS             complement(293798..295633)
                     /gene="fadE5"
                     /locus_tag="Y980_0244c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0244c, (MTV034.10c) Probable fadE5,acyl-CoA
                     dehydrogenase, equivalent to AL022486|MLCB1883_15 from
                     Mycobacterium leprae (611 aa). Also highly similar to
                     AL0211|MTV007.14 from Mycobacterium tuberculosis (609 aa);
                     and to various other bacterial proteins described as
                     putative acyl-CoA dehydrogenases e.g. AE0010|AE001025_6
                     from Archaeoglobus fulgidus (387 aa); etc."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA dehydrogenase FadE5"
                     /protein_id="AJF01594.1"
                     /db_xref="GOA:L7N547"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR006092"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="InterPro:IPR020953"
                     /db_xref="InterPro:IPR025878"
                     /db_xref="UniProtKB/TrEMBL:L7N547"
                     /translation="MSHYRSNVRDQVFNLFEVLGVDKALGHGEFSDVDVDTARDMLAE
                     VSRLAEGPVAESFVEGDRNPPVFDPKTHSVMLPESFKKSVNAMLEAGWDKVGIDEALG
                     GMPMPKAVVWALHEHILGANPAVWMYAGGAGFAQILYHLGTEEQKKWAVLAAERGWGS
                     TMVLTEPDAGSDVGAARTKAVQQADGSWHIDGVKRFITSGDSGDLFENIFHLVLARPE
                     GAGPGTKGLSLYFVPKFLFDVETGEPGERNGVFVTNVEHKMGLKVSATCELAFGQHGV
                     PAKGWLVGEVHNGIAQMFEVIEQARMMVGTKAIATLSTGYLNALQYAKSRVQGADLTQ
                     MTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDAAVAEVVHGVDAKLA
                     VKVNDLMLPVVKGVGSEQAYAKLTESLQTLGGSGFLQDYPIEQYIRDAKIDSLYEGTT
                     AIQAQDFFFRKIVRDKGVALAHVSGQIQEFVDSGAGNGRLKTERALLAKALTDVQGMA
                     AALTGYLMAAQQDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVAALDAGATGD
                     ERSFYEGKVAVASFFAKNFLPLLTSTREVIETLDNDIMELDEAAF"
     gene            296005..296493
                     /locus_tag="Y980_0245"
     CDS             296005..296493
                     /locus_tag="Y980_0245"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0245, (MTV034.11) Possible oxidoreductase,
                     equivalent to AL022486|MLCB1883_17|T44882 probable
                     oxidoreductase from Mycobacterium leprae (162 aa). Also
                     similar to several hypothetical proteins and various
                     oxidoreductases e.g. AAK24246.1|AE005898 NADH:riboflavin
                     5'-phosphate oxidoreductase from Caulobacter crescentus
                     (174 aa); Q02058|DIM6_STRCO|CAA45048.1 actinorhodin
                     polyketide dimerase from streptomyces coelicolor (177 aa).
                     Also similar to Z84498|Rv1939|MTCY09F9.25c from
                     Mycobacterium tuberculosis (171 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative oxidoreductase"
                     /protein_id="AJF01595.1"
                     /db_xref="GOA:L7N5R9"
                     /db_xref="InterPro:IPR002563"
                     /db_xref="InterPro:IPR012349"
                     /db_xref="UniProtKB/TrEMBL:L7N5R9"
                     /translation="MNSTNNLTPSSLREAFGHFPTGVVAIAAEVDGVRQGLAASTFVP
                     VSLEPPLVSFCVQNTSTTWPKLTGVPMLGISVLGEAHDAAVRTLAAKTGDRFAGLETV
                     SNDAGAVFIKGTSVWLESAIEQLVPAGDHTIVVLRVNQVKVDPNVAPIVFHRSVLRRL
                     GV"
     gene            296809..298119
                     /locus_tag="Y980_0246"
     CDS             296809..298119
                     /locus_tag="Y980_0246"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0246, (MTV034.12), len: 436 aa (start uncertain).
                     Probable conserved integral membrane protein, similar to
                     Rv2209|1237062|CAA94252.1|Z70283|Q10398|YM09_MYCTU from
                     Mycobacterium tuberculosis (512 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative conserved integral membrane protein"
                     /protein_id="AJF01596.1"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="UniProtKB/TrEMBL:L0T333"
                     /translation="MAKTSHRVSSADGMSKRILRLIIAQSGFYSAALQLGNVSIVLPF
                     VVAELDAELWIAALIFPAFTAGGAIGNVVAPPAVAAVPRRHRLFIIVSCLAVLAGVNA
                     LCATIGKGSVAGILLVVNVTLIGVVSAISFVAFADLVAAMPSGTARARILLTEVGVGA
                     ALTAVVAATLSFVPDQHPLSRNIHLLWTAAVAMAISAAICRALPHRIVPRVHAAPGLH
                     KLVYVGWTAIRTNGWYRRYLLVQVLFGSVVLGSSFHSIRVAAVPGDQPDEVVAVVLFV
                     CVGLLGGIALWNRVRERFGLVGLFVGSALVSIAAAVLSIAFDLAGAWPNVVAIGLVIA
                     LVSIANQSVFTAGQLWIARDAEPGLRTSLISFGQLVINAGLVGMGLALGLIAQDHDAV
                     WPVMIVLLLNLTAAYSATRFAPAKSVDVRGLPQVSRTSRPKTGG"
     gene            complement(298116..298862)
                     /locus_tag="Y980_0247c"
     CDS             complement(298116..298862)
                     /locus_tag="Y980_0247c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00197"
                     /note="Rv0247c, (MTV034.13c) Probable succinate
                     dehydrogenase, iron-sulfur subunit, highly similar to
                     CAC44313.1|AL596043 putative succinate dehydrogenase
                     iron-sulfur subunit from Streptomyces coelicolor (259 aa);
                     and similar to iron-sulphur protein subunits of fumarate
                     reductase or succinate dehydrogenases from many bacteria
                     e.g. NP_147618.1|7521083|B72691 fumarate reductase
                     iron-sulfur protein from Aeropyrum pernix (305 aa);
                     NP_069516.1|2649932|AAB90556.1|AE001057 succinate
                     dehydrogenase iron-sulfur subunit B (sdhB) from
                     Archaeoglobus fulgidus (236 aa); etc. Also similar to
                     Q10761|FRDB_MYCTU|7431693|F70762 fumarate reductase
                     iron-sulfur protein from Mycobacterium tuberculosis (247
                     aa). Contains PS00197 2Fe-2S ferredoxins,iron-sulfur
                     binding region signature. Note that succinate
                     dehydrogenase forms generally part of an enzyme complex
                     containing four subunits: a flavoprotein (Rv0248c ?), an
                     iron-sulfur (Rv0247c ?), and two hydrophobic anchor
                     proteins (Rv0249c ?)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative succinate dehydrogenase [iron-sulfur
                     subunit] (succinic dehydrogenase)"
                     /protein_id="AJF01597.1"
                     /db_xref="GOA:L7N4K2"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR004489"
                     /db_xref="InterPro:IPR006058"
                     /db_xref="InterPro:IPR009051"
                     /db_xref="InterPro:IPR012285"
                     /db_xref="InterPro:IPR012675"
                     /db_xref="InterPro:IPR017896"
                     /db_xref="UniProtKB/TrEMBL:L7N4K2"
                     /translation="MTYSASMRVWRGDESCGELREFTVEVNEGEVVLDVILRLQQTQT
                     PDLAVRWNCKAGKCGSCSAEINGKPRLMCMTRMSTFDEDEIVTVTPMRTFPVIRDLVT
                     DVSFNYQKAREIPSFAPPKELQPSEYRMAQVDVARSQEFRKCIECFLCQNVCHVVRDH
                     EENKDAFAGPRFLMRIAELEMHPLDTRDRRSQAQEEHGLGYCNITKCCTEVCPENIKI
                     TDNALIPMKERVADRKYDPVVWLGSKLFRR"
     gene            complement(298863..300803)
                     /locus_tag="Y980_0248c"
     CDS             complement(298863..300803)
                     /locus_tag="Y980_0248c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00017"
                     /inference="protein motif:PROSITE:PS00141"
                     /note="Rv0248c, (MTV034.14c) Probable succinate
                     dehydrogenase, flavoprotein subunit, highly similar to
                     flavoprotein subunit of various succinate dehydrogenases
                     e.g. M88696|RIRSDHA_1 flavoprotein from Rickettsia
                     prowazekii (596 aa). Also similar to truncated U00022_17
                     flavoprotein from Mycobacterium leprae (401 aa). Note that
                     succinate dehydrogenase forms generally part of an enzyme
                     complex containing four subunits: a flavoprotein (Rv0248c
                     ?), an iron-sulfur (Rv0247c ?), and two hydrophobic anchor
                     proteins (Rv0249c ?)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative succinate dehydrogenase [iron-sulfur
                     subunit] (succinic dehydrogenase)"
                     /protein_id="AJF01598.1"
                     /db_xref="GOA:L7N5C5"
                     /db_xref="HSSP:P00363"
                     /db_xref="InterPro:IPR003953"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="InterPro:IPR014006"
                     /db_xref="InterPro:IPR015939"
                     /db_xref="InterPro:IPR027477"
                     /db_xref="UniProtKB/TrEMBL:L7N5C5"
                     /translation="MVEVERHSYDVVVIGAGGAGLRAVIEARERGLKVAVVCKSLFGK
                     AHTVMAEGGCAAAMGNANPKDNWKTHFGDTMRGGKFLNNWRMAELHAKEAPDRVWELE
                     TYGALFDRTDDGRISQRNFGGHTYPRLAHVGDRTGLELIRTLQQKVVSLQQEDHAELG
                     DYEARIKVFAECTITELLKDQGAIAGAFGYWRESGRFIVFEAPAVVLATGGIGKSFKV
                     TSNSWEYTGDGHALALRAGATLINMEFVQFHPTGMVWPPSVKGILVTEGVRGDGGVLK
                     NSENSRFMFDYIPPVFKGQYAETEEEADQWLKDNDSARRTPDLLPRDEVARAINSEVK
                     AGRGTPHGGVYLDIASRLTPAEIKRRLPSMYHQFKELAEVDITTQAMEVGPTCHYVMG
                     GVEVDADTGAATVPGLFAAGECAGGMHGSNRLGGNSLSDLLVFGRRAGLGAADYVRAL
                     SSRPAVSAEAIDAAAQQALSPFEGPKDGSAPENPYALHMDLQYVMNDLVGIIRNADEI
                     SRALTLLAELWSRYHNVLVEGHRQYNPGWNLSIDLRNMLLVSECVARAALQRTESRGG
                     HTRDDHPGMDPNWRRILLVCRATETMGTGGSGSGDSNCHINVTQQLQTPMRPDLLELF
                     EISELEKYYTDEELAEHPGRRG"
     gene            complement(300834..301655)
                     /locus_tag="Y980_0249c"
     CDS             complement(300834..301655)
                     /locus_tag="Y980_0249c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0249c, (MTV034.15c) Probable succinate
                     dehydrogenase, membrane-anchor subunit for succinate
                     dehydrogenase encoded by Rv0247c and Rv0248c. Highly
                     similar to AC44315.1|AL596043 putative integral membrane
                     protein from Streptomyces coelicolor (278 aa). Note that
                     succinate dehydrogenase forms generally part of an enzyme
                     complex containing four subunits: a flavoprotein (Rv0248c
                     ?), an iron-sulfur (Rv0247c ?), and two hydrophobic anchor
                     proteins (Rv0249c ?)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative succinate dehydrogenase [membrane
                     anchor subunit] (succinic dehydrogenase)"
                     /protein_id="AJF01599.1"
                     /db_xref="UniProtKB/TrEMBL:L7N615"
                     /translation="MSAPTANRPAIGVFTPTRAQIPERTLRTDLWWLPPLLTNLGLLA
                     FICYATTRAFWGSQYWVEKYHYLTPFYSPCVSASCQPGASHLGVWFGHFPGWIPLGAM
                     VLPFLLGFRLTCYYYRKAYYRSVWQSPTSCAVPEPRAHYTGETRLPLIVQNTHRYFFY
                     IAVVVSLINTYDAIAAFHSPSGFGFGLGNVILTINVVLLWAYTISCHSCRHATGGRLK
                     HFSKHPVRYWIWTQVSKLNTRHMQFAWITLGTLALTDFYIMLVASGSITDLRFIG"
     gene            complement(301735..302028)
                     /locus_tag="Y980_0250c"
     CDS             complement(301735..302028)
                     /locus_tag="Y980_0250c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0250c, (MTV034.16c) Conserved protein, equivalent
                     to MLCB1883.27c|T44883|3063888|CAA18576.1|AL022486
                     hypothetical protein from Mycobacterium leprae (98 aa).
                     Also similar to C-terminus of
                     AC44316.1|AL596043|SCBAC31E11.05c hypothetical protein
                     from Streptomyces coelicolor (146 aa). A core
                     mycobacterial gene; conserved in mycobacterial strains
                     (See Marmiesse et al., 2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01600.1"
                     /db_xref="UniProtKB/Swiss-Prot:O53672"
                     /translation="MSTTAELAELHDLVGGLRRCVTALKARFGDNPATRRIVIDADRI
                     LTDIELLDTDVSELDLERAAVPQPSEKIAIPDTEYDREFWRDVDDEGVGGHRY"
     gene            complement(302173..302652)
                     /gene="hsp"
                     /locus_tag="Y980_0251c"
                     /gene_synonym="acr2"
                     /gene_synonym="hrpA"
                     /gene_synonym="hsp20"
     CDS             complement(302173..302652)
                     /gene="hsp"
                     /locus_tag="Y980_0251c"
                     /gene_synonym="acr2"
                     /gene_synonym="hrpA"
                     /gene_synonym="hsp20"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0251c, (MTV034.17c) Hsp (alternate gene name:
                     hsp20, hrpA, acr2), heat-stress-induced ribosome-binding
                     protein A (see citations below). Highly similar to
                     AAD39038.1|AF072875_1|AF072875 putative HSP20 from
                     Mycobacterium smegmatis (145 aa); and similar to many
                     bacterial and eukaryotic hsp proteins e.g.
                     P12811|HS2C_CHLRE chloroplast heat shock 22KD protein from
                     chlamydomonas reinhardtii (157 aa). Also similar to
                     PCC6803 Spore protein sp21 from Synechocystis sp. (146
                     aa). Also similar to P30223|14KD_MYCTU 14 KDA antigen (16
                     KDA antigen) 19K major membrane protein (HSP 16.3) from
                     Mycobacterium tuberculosis (144 aa). Belongs to the small
                     heat shock protein (HSP20) family."
                     /codon_start=1
                     /transl_table=11
                     /product="Heat shock protein Hsp (heat-stress-induced
                     ribosome-binding protein A)"
                     /protein_id="AJF01601.1"
                     /db_xref="GOA:L7N524"
                     /db_xref="InterPro:IPR002068"
                     /db_xref="InterPro:IPR008978"
                     /db_xref="UniProtKB/TrEMBL:L7N524"
                     /translation="MNNLALWSRPVWDVEPWDRWLRDFFGPAATTDWYRPVAGDFTPA
                     AEIVKDGDDAVVRLELPGIDVDKDVNVELDPGQPVSRLVIRGEHRDEHTQDAGDKDGR
                     TLREIRYGSFRRSFRLPAHVTSEAIAASYDAGVLTVRVAGAYKAPAETQAQRIAITK"
     gene            302866..305427
                     /gene="nirB"
                     /locus_tag="Y980_0252"
                     /gene_synonym="nasB"
     CDS             302866..305427
                     /gene="nirB"
                     /locus_tag="Y980_0252"
                     /gene_synonym="nasB"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00365"
                     /note="Rv0252, (MTV034.18) Probable nirB (alternate gene
                     name: nasB), nitrite reductase [NAD(P)H] large subunit,
                     flavoprotein containing siroheme and a 2FE-2S iron-sulfur
                     centre. Highly similar to many others bacterial enzymes
                     e.g. P08201|NIRB_ECOLI nitrite reductase (NAD(P)H) large
                     subunit from Escherichia coli strain K12 (847 aa);
                     Q06458|NIRB_KLEPN nitrite reductase (NAD(P)H) large
                     subunit (957 aa). Contains PS00365 Nitrite and sulfite
                     reductases iron-sulfur/siroheme-binding site. Homodimer
                     which associates with NIRD|Rv0253. Cofactors: FAD; Iron;
                     Siroheme."
                     /codon_start=1
                     /transl_table=11
                     /product="putative nitrite reductase [NAD(P)H] large
                     subunit [FAD flavoprotein] NirB"
                     /protein_id="AJF01602.1"
                     /db_xref="GOA:L0T645"
                     /db_xref="InterPro:IPR001327"
                     /db_xref="InterPro:IPR005117"
                     /db_xref="InterPro:IPR006066"
                     /db_xref="InterPro:IPR006067"
                     /db_xref="InterPro:IPR007419"
                     /db_xref="InterPro:IPR012744"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="InterPro:IPR017121"
                     /db_xref="InterPro:IPR023753"
                     /db_xref="UniProtKB/TrEMBL:L0T645"
                     /translation="MPTAGSSRAPAAAREIVVVGHGMVGHRLVEAVRARDADGSLRIT
                     VLAEEGDAAYDRVGLTSYTESWDRALLALPGNDYAGDQRVRLLLNTRVTQIDRATKSV
                     VTAAGQRHRYDTLVLATGSYAFVPPVPGHDLPACHVYRTFDDLDAIRAGAQRTLDGGH
                     TDGGVVIGGGLLGLEAANALRQFGLQTHVVEMMPRLMAQQIDEAGGALLARMIADLGI
                     AVHVGTGTESIESVKHSDGSVWARVRLSDGEVIDAGVVIFAAGIRPRDELARAAGLAI
                     GDRGGVLTDLSCRTSDPDIYAVGEVAAIDGRCYGLVGPGYTSAEVVADRLLDGSAEFP
                     EADLSTKLKLLGVDVASFGDAMGATENCLEVVINDAVKRTYAKLVLSDDATTLLGGVL
                     VGDASSYGVLRPMVGAELPGDPLALIAPAGSGAGAGALGVGALPDSAQICSCNNVTKG
                     ELKCAIADGCGDVPALKSCTAAGTSCGSCVPLLKQLLEAEGVEQSKALCEHFSQSRAE
                     LFEIITATEVRTFSGLLDRFGRGKGCDICKPVVASILASTGSDHILDGEQASLQDSND
                     HFLANIQKNGSYSVVPRVPGGDIKPEHLILIGQIAQDFGLYTKITGGQRIDLFGARVD
                     QLPLIWQRLVDGGMESGHAYGKAVRTVKSCVGSDWCRYGQQDSVQLAIDLELRYRGLR
                     APHKIKLGVSGCARECAEARGKDVGVIATEKGWNLYVAGNGGMTPKHAQLLASDLDKE
                     TLIRYIDRFLIYYIRTADRLQRTAPWVESLGLDHVREVVCEDSLGLAEEFEAAMQRHV
                     ANYKCEWKGVLEDPDKLSRFVSFVNAPDAVDSTVTFTERAGRKVPVSIGIPRVRS"
     gene            305453..305809
                     /gene="nirD"
                     /locus_tag="Y980_0253"
     CDS             305453..305809
                     /gene="nirD"
                     /locus_tag="Y980_0253"
                     /note="Rv0253, (MTV034.19) Probable nirD,nitrite reductase
                     [NAD(P)H] small subunit, similar to others e.g.
                     P23675|NIRD_ECOLI|B3366|Z4727|ECS4217 from Escherichia
                     coli strains K12 and O157:H7 (108 aa). Associates with
                     NIRB|Rv0252."
                     /codon_start=1
                     /transl_table=11
                     /product="putative nitrite reductase [NAD(P)H] small
                     subunit NirD"
                     /protein_id="AJF01603.1"
                     /db_xref="GOA:O53675"
                     /db_xref="InterPro:IPR012748"
                     /db_xref="InterPro:IPR017881"
                     /db_xref="InterPro:IPR017941"
                     /db_xref="PDB:4AIV"
                     /db_xref="UniProtKB/TrEMBL:O53675"
                     /translation="MTLLNDIQVWTTACAYDHLIPGRGVGVLLDDGSQVALFRLDDGS
                     VHAVGNVDPFSGAAVMSRGIVGDRGGRAMVQSPILKQAFALDDGSCLDDPRVSVPVYP
                     ARVTPEGRIQVARVAV"
     gene            complement(305825..306349)
                     /gene="cobU"
                     /locus_tag="Y980_0254c"
     CDS             complement(305825..306349)
                     /gene="cobU"
                     /locus_tag="Y980_0254c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00017"
                     /note="Rv0254c, (MTV034.20) Probable cobU,cobalamin
                     biosynthesis protein including a cobinamide kinase and
                     cobinamide phosphate guanylyltransferase. Highly similar
                     to many e.g. Q05599|COBU_SALTY cobinamide kinase /
                     cobinamide phosphate guanylyltransferase from Salmonella
                     typhimurium (181 aa);
                     P46886|COBU_ECOLI|B1993|Z3153|ECS2788 Bifunctional
                     cobalamin biosynthesis protein cobU from Escherichia coli
                     strains K12 and O157:H7 (181 aa); part of
                     AL096872|SC5F7_10 from Streptomyces coelicolor (397 aa);
                     etc. Contains PS00017 ATP/GTP-binding site motif A
                     (P-loop)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative bifunctional cobalamin biosynthesis
                     protein CobU: cobinamide kinase + cobinamide phosphate
                     guanylyltransferase"
                     /protein_id="AJF01604.1"
                     /db_xref="GOA:L7N4T1"
                     /db_xref="InterPro:IPR003203"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:L7N4T1"
                     /translation="MRILVTGGVRSGKSTHAEALLGDAADVVYVAPGRPAAGSDPDWD
                     ARVALHRARRPPTWLTVETADVATALSEARSPVLVDCLGTWLTAIMDGEALWSAATAD
                     VYAVLEARLDGLCAALTGLPTAIVVTNEVGLGVVPSHSSGVLFRDLLGTINRRVAAVC
                     DEVHLVIAGRVLKL"
     gene            complement(306374..307858)
                     /gene="cobQ1"
                     /locus_tag="Y980_0255c"
                     /gene_synonym="cobQ"
     CDS             complement(306374..307858)
                     /gene="cobQ1"
                     /locus_tag="Y980_0255c"
                     /gene_synonym="cobQ"
                     /note="Rv0255c, (MTV034.21c) Probable cobQ1,cobyric acid
                     synthase, similar to many e.g. Z46611|RCBLUGNS_8 cobyric
                     acid synthase from R.capsulatus (483 aa);
                     P29932|COBQ_PSEDE cobyric acid synthase from Pseudomonas
                     denitrificans (484 aa); etc. Belongs to the COBB/COBQ
                     family, COBQ subfamily. Note that previously known as
                     cobQ."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cobyric acid synthase CobQ1"
                     /protein_id="AJF01605.1"
                     /db_xref="GOA:P0A532"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="InterPro:IPR004459"
                     /db_xref="InterPro:IPR011698"
                     /db_xref="InterPro:IPR017929"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/Swiss-Prot:P0A532"
                     /translation="MSGLLVAGTTSDAGKSAVTAGLCRALARRGVRVAPFKAQNMSNN
                     SMVCRGPDGTGVEIGRAQWVQALAARTTPEAAMNPVLLKPASDHRSHVVLMGKPWGEV
                     ASSSWCAGRRALAEAACRAFDALAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAG
                     LPTIVVGDIDRGGVFAAFLGTVALLAAEDQALVAGFVVNKFRGDSDLLAPGLRDLERV
                     TGRRVYGTLPWHPDLWLDSEDALDLQGRRAAGTGARRVAVVRLPRISNFTDVDALGLE
                     PDLDVVFASDPRALDDADLIVLPGTRATIADLAWLRARDLDRALLVHVAAGKPLLGIC
                     GGFQMLGRVIRDPYGIEGPGGQVTEVEGLGLLDVETAFSPHKVLRLPRGEGLGVPASG
                     YEIHHGRITRGDTAEEFLGGARDGPVFGTMWHGSLEGDALREAFLRETLGLAPSGSCF
                     LAARERRLDLLGDLVERHLDVDALLNLARHGCPPTLPFLAPGAP"
     gene            complement(307877..309547)
                     /gene="PPE2"
                     /locus_tag="Y980_0256c"
     CDS             complement(307877..309547)
                     /gene="PPE2"
                     /locus_tag="Y980_0256c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0256c, (MTV034.22c) PPE2, Member of the M.
                     tuberculosis PPE family, similar to many e.g. Rv0280,
                     Rv0286, etc. Equivalent to Z98756|MLCB2492.30 from
                     Mycobacterium leprae (572 aa). A core mycobacterial gene;
                     conserved in mycobacterial strains (See Marmiesse et al.,
                     2004)."
                     /codon_start=1
                     /transl_table=11
                     /product="PPE family protein PPE2"
                     /protein_id="AJF01606.1"
                     /db_xref="GOA:Q79FZ4"
                     /db_xref="InterPro:IPR000030"
                     /db_xref="UniProtKB/Swiss-Prot:Q79FZ4"
                     /translation="MTAPIWMASPPEVHSALLSSGPGPGPLLVSAEGWHSLSIAYAET
                     ADELAALLAAVQAGTWDGPTAAVYVAAHTPYLAWLVQASANSAAMATRQETAATAYGT
                     ALAAMPTLAELGANHALHGVLMATNFFGINTIPIALNESDYARMWIQAATTMASYQAV
                     STAAVAAAPQTTPAPQIVKANAPTAASDEPNQVQEWLQWLQKIGYTDFYNNVIQPFIN
                     WLTNLPFLQAMFSGFDPWLPSLGNPLTFLSPANIAFALGYPMDIGSYVAFLSQTFAFI
                     GADLAAAFASGNPATIAFTLMFTTVEAIGTIITDTIALVKTLLEQTLALLPAALPLLA
                     APLAPLTLAPASAAGGFAGLSGLAGLVGIPPSAPPVIPPVAAIAPSIPTPTPTPAPAP
                     APTAVTAPTPPPGPPPPPVTAPPPVTGAGIQSFGYLVGDLNSAAQARKAVGTGVRKKT
                     PEPDSAEAPAAAAAPEEQVQPQRRRRPKIKQLGRGYEYLDLDPETGHDPTGSPQGAGT
                     LGFAGTTHKASPGQVAGLITLPNDAFGGSPRTPMMPGTWDTDSATRVE"
     gene            309699..310073
                     /locus_tag="Y980_0257"
     CDS             309699..310073
                     /locus_tag="Y980_0257"
                     /note="Rv0257 Hypothetical protein,orthologue of ML1828A
                     conserved hypothetical protein from Mycobacterium leprae.
                     Replaced Rv0257c (older annotation). A core mycobacterial
                     gene; conserved in mycobacterial strains (See Marmiesse et
                     al., 2004). Predicted to be an outer membrane protein (See
                     Song et al., 2008)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01607.1"
                     /db_xref="UniProtKB/TrEMBL:Q8VKP3"
                     /translation="MTRVSWLPDRCLPRLPACGRGLRGSLPGDSGGTAPDSHRLPASS
                     SPDGKNIGMQSVDLHVERHLPSRGRSHRTVATVTCVTALGDIRSAQLSATGAWPAVLF
                     PSWSWLCGIGGGVDLQKPSCRA"
     gene            complement(310294..310749)
                     /locus_tag="Y980_0258c"
     CDS             complement(310294..310749)
                     /locus_tag="Y980_0258c"
                     /note="Rv0258c, (MTCY06A4.02c), len: 151 aa (alternative
                     start possible). Conserved hypothetical protein, showing
                     some similarity to Rv1685c|MTCI125_6 from Mycobacterium
                     tuberculosis (207 aa). Also some similarity with
                     AL049819|SCE7_13|T36295 probable transcription regulator
                     from Streptomyces coelicolor (204 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01608.1"
                     /db_xref="GOA:L7N5G1"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:L7N5G1"
                     /translation="MARSQEPSRGLLDPVAKMLRLPFGTPDFIEKIVTGSVNQVGRRT
                     LYVLITTWDAAGGGPFAASAIATTGLAKTAEIVQSMFIGPVFNPLLKMLGADKIAIRA
                     SLCAAQLVGLGIMRYGVRSEPLHSMSVEMLVDAIGPTMQRYLVGDIGRG"
     gene            complement(310774..311517)
                     /locus_tag="Y980_0259c"
     CDS             complement(310774..311517)
                     /locus_tag="Y980_0259c"
                     /note="Rv0259c, (MTCY06A4.03c) Conserved hypothetical
                     protein, showing some similarity to
                     Rv2393|Z81368|MTCY253_28 from Mycobacterium tuberculosis
                     (281 aa). Also some similarity with CAC33938.1|AL589708
                     putative secreted protein from Streptomyces coelicolor
                     (248 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01609.1"
                     /db_xref="GOA:L0T4U7"
                     /db_xref="InterPro:IPR002762"
                     /db_xref="UniProtKB/TrEMBL:L0T4U7"
                     /translation="MNLILTAHGTRRPSGVAMIADIAAQVSALVDRTVQVAFVDVLGP
                     SPSEVLSALSCRPAIVVPAFLSRGYHVRTDLPAHVAASAHPHVTVTPALGPCREIAQI
                     VTQQLVESGWRPGDSVILAAAGASDRRARADLHTTRTLVSELTGSWVDMGFAGTGGPD
                     VRTAVQRARDRAEANRGARRVAVASFLLAEGLFQERLRASGADVVTRPLGTHPGLAQL
                     VANRFRSAVARQQRLHRWHGTPTPVTLDL"
     gene            complement(311514..312659)
                     /locus_tag="Y980_0260c"
     CDS             complement(311514..312659)
                     /locus_tag="Y980_0260c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0260c, (MTCY0A4.04c) Possible two-component
                     response regulator, highly similar to CAB72204.1|AL138851
                     putative transcriptional regulator from Streptomyces
                     coelicolor (395 aa); and similar to O34394|D69851|YJJA
                     conserved hypothetical protein from Bacillus subtilis (270
                     aa). Also some similarity to regulatory proteins at
                     C-terminal region e.g. CUTR_STRLI|Q03756 transcriptional
                     regulatory protein (217 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein"
                     /protein_id="AJF01610.1"
                     /db_xref="GOA:L7N4Q5"
                     /db_xref="InterPro:IPR001867"
                     /db_xref="InterPro:IPR003754"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR016032"
                     /db_xref="UniProtKB/TrEMBL:L7N4Q5"
                     /translation="MAQAHSAPLTGYRIAVTSARRAEELCALLRRQGAEVCSAPAIKM
                     IALPDDDELQNNTEALIADPPDILVAHTGIGFRGWLAAAEGWGLANELLESLSSARII
                     SRGPKATGALRAAGLREEWSPDSESSHEVLEYLLESGVSRTRIAVQLHGAADSWDPFP
                     EFLGGLRFAGAQVVPIRVYRWKPAPLGGVFDHLVTGIARRQFDAVTFTSAPAAAAVLE
                     RSRELDIEDQLLAALRTDVHAMCVGPVTSRPLIRKGVPTSAPERMRLGALARHIAEEL
                     PLLGSCTFKAAGHVIEIRGTSVLVDDSVKPLSPSGMAILRALVHRPGGVVSRGDLLRV
                     LPGDGSDTHAVDTAVLRLRTALGDKNIVATVVKRGYRLAVDSRHDDV"
     gene            complement(312759..314168)
                     /gene="narK3"
                     /locus_tag="Y980_0261c"
     CDS             complement(312759..314168)
                     /gene="narK3"
                     /locus_tag="Y980_0261c"
                     /note="Rv0261c, (MTCY06A4.05c) Probable nirK3, nitrite
                     extrusion protein, integral membrane protein possibly
                     member of major facilitator superfamily (MFS),equivalent
                     to AAB41700.1|U72744 nitrite extrusion protein from
                     Mycobacterium fortuitum (471 aa); and
                     2342627|CAB11406.1|Z98741|T44908 nitrite extrusion protein
                     homolog from Mycobacterium leprae (517 aa; longer in
                     N-terminus). Also similar to other nitrite extrusion
                     proteins e.g. NARK_ECOLI|P10903|B1223 nitrite extrusion
                     protein 1 from Escherichia coli strain K12 (463 aa).
                     Belongs to the nark/NASA family of transporters."
                     /codon_start=1
                     /transl_table=11
                     /product="putative integral membrane nitrite extrusion
                     protein NarK3 (nitrite facilitator)"
                     /protein_id="AJF01611.1"
                     /db_xref="GOA:L7N5B0"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="UniProtKB/TrEMBL:L7N5B0"
                     /translation="MGRSHQISDWDPEDSVAWEAGNKFIARRNLIWSVAAEHVGFSVW
                     SLWSVMVLFMPTSVYGFSAGDKFLLGATATLVGACLRFPYTFATAKFGGRNWTIFSAL
                     VLLIPTVGSILLLANPGLPLWPYLVCGALAGLGGGNFAASMTNINAFFPQRLKGAALA
                     LNAGGGNLGVPMVQLVGLLVIATAGDREPYWVCAIYLVLLAVAGLGAALYMDNLTEYR
                     IELNTMRAVVSEPHTWVISLLYIGTFGSFIGFSFAFGQVLQINFIASGQSTAQASLHA
                     AQIAFLGPLLGSLSRIYGGKLADRIGGGRVTLAAFCAMLLATGILISASTFGDHLAGP
                     MPTATMVGYVIGFTALFILSGIGNGSVYKMIPSIFEARSHSLQISEAERRQWSRSMSG
                     ALIGLAGAVGALGGVGVNLALRESYLTSGTATSAFWAFGVFYLVASVLTWAIYVRRGL
                     KSAGELVPATTAPAGLAYV"
     gene            complement(314309..314854)
                     /gene="aac"
                     /locus_tag="Y980_0262c"
     CDS             complement(314309..314854)
                     /gene="aac"
                     /locus_tag="Y980_0262c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0262c, (MTCY06A4.06c) Aac,aminoglycoside
                     2'-N-acetyltransferase (aac(2')-IC) (see citation below),
                     highly similar to NP_302635.1|NC_002677 aminoglycoside
                     2'-N-acetyltransferase from Mycobacterium leprae (182 aa);
                     Q49157|AAC2_MYCFO|AAC aminoglycoside
                     2'-N-acetyltransferase from Mycobacterium fortuitum (195
                     aa), Contains GNAT (Gcn5-related N-acetyltransferase)
                     domain. See Vetting et al. 2005. P94968|AAC2_MYCSM|AAC
                     aminoglycoside 2'-N-acetyltransferase from Mycobacterium
                     smegmatis (210 aa) (see also citation below). Also similar
                     to Q52424|AAC2_PROST aminoglycoside 2'-N-acetyltransferase
                     from Providencia stuartii (178 aa). Belongs to the
                     AAC(2')-I family of acetyltransferases. Note that
                     previously known as aac(2')-IC."
                     /codon_start=1
                     /transl_table=11
                     /product="Aminoglycoside 2'-N-acetyltransferase Aac
                     (Aac(2')-IC)"
                     /protein_id="AJF01612.1"
                     /db_xref="GOA:P0A5N0"
                     /db_xref="InterPro:IPR000182"
                     /db_xref="InterPro:IPR016181"
                     /db_xref="PDB:1M44"
                     /db_xref="PDB:1M4D"
                     /db_xref="PDB:1M4G"
                     /db_xref="PDB:1M4I"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5N0"
                     /translation="MHTQVHTARLVHTADLDSETRQDIRQMVTGAFAGDFTETDWEHT
                     LGGMHALIWHHGAIIAHAAVIQRRLIYRGNALRCGYVEGVAVRADWRGQRLVSALLDA
                     VEQVMRGAYQLGALSSSARARRLYASRGWLPWHGPTSVLAPTGPVRTPDDDGTVFVLP
                     IDISLDTSAELMCDWRAGDVW"
     gene            complement(314864..315766)
                     /locus_tag="Y980_0263c"
     CDS             complement(314864..315766)
                     /locus_tag="Y980_0263c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0263c, (MTCY06A4.07c) Conserved hypothetical
                     protein, equivalent to NP_302634.1|NC_002677 conserved
                     hypothetical protein from Mycobacterium leprae (305 aa).
                     Also similar to others e.g. AL121596|SC51A_21 hypothetical
                     protein from Streptomyces coelicolor (285 aa);
                     NP_233164.1|NC_002506 conserved hypothetical protein from
                     Vibrio cholerae (309 aa); NP_406216.1|NC_003143 conserved
                     hypothetical protein from Yersinia pestis (316 aa);
                     YH30_HAEIN|P44298|hi1730 hypothetical protein from
                     Haemophilus influenzae (309 aa); etc. Also similar to
                     carboxylases eg NP_415240.1|NC_000913|P75745|YBGK_ECOLI
                     putative carboxylase from Escherichia coli strain K12 (310
                     aa); NP_459698.1|NC_003197 putative carboxylase from
                     Salmonella typhimurium (310 aa); and to middle part of
                     NP_420636.1|NC_002696 urea amidolyase-related protein from
                     Caulobacter crescentus (1207 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01613.1"
                     /db_xref="InterPro:IPR003778"
                     /db_xref="UniProtKB/TrEMBL:L0T5Y3"
                     /translation="MTTLEILRSGPLALVEDLGRAGLAHLGVGRSGAADRRSHTLANR
                     LVANPDDWATVEVTFGGFSARVRGGDVDIAVTGADTDPTVNGIMVGTNSIHHVRDGQV
                     ISLGTPRAGLRTYLAVRGGVCVEPVLGSRSYDVMSAIGPSPLRAGDVLPVGEHTDDYP
                     ELDQAPVAAIEEHLVELRVVPGPRDDWLVDPDALVHTIWMASNRSDRVGMRLQGRPLQ
                     HRWPDRQLPGEGVTRGAIQVPPNGLPVILGPDHPITGSYPVVGVITDEDIDKVAQIRP
                     GQYVRLHWARPRSRLPGQGVTQAW"
     gene            complement(315783..316415)
                     /locus_tag="Y980_0264c"
     CDS             complement(315783..316415)
                     /locus_tag="Y980_0264c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0264c, (MTCY06A4.08c) Conserved hypothetical
                     protein, equivalent to CAC32080.1|AL583926 conserved
                     hypothetical protein from Mycobacterium leprae (222 aa).
                     Also similar to others hypothetical proteins e.g.
                     AL121596|SC51A_20 from Streptomyces coelicolor (252 aa);
                     P75744|YBGJ_ECOLI hypothetical 23.9 KD protein from
                     Escherichia coli (218 aa); YH31_HAEIN|P44299|hi173
                     hypothetical protein from Haemophilus influenzae (213
                     aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01614.1"
                     /db_xref="InterPro:IPR003833"
                     /db_xref="InterPro:IPR024946"
                     /db_xref="UniProtKB/TrEMBL:L0T4V1"
                     /translation="MDAALACTVLDYGDHALMLQCDSTADAMAWTDALRAAALPGVVD
                     IVAASRTVLVKLDAPRYQGVTRQRLRRLRVTPEAVAAADHRCDLVIDVVYDGPDLAEV
                     ARCTGLTTAAVINAHTATGWRAGFSGSAPGFAYLIDGDPSLRVPRRPERRTSMPPGSV
                     ALADGFSAIYPSQAPSDWQIIGHTDAVLWDVDRPQPALLTPGMWVQFRAA"
     gene            complement(316511..317503)
                     /locus_tag="Y980_0265c"
     CDS             complement(316511..317503)
                     /locus_tag="Y980_0265c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00013"
                     /note="Rv0265c, (MTCY06A4.09c) Probable iron-transport
                     lipoprotein, most similar to
                     T36412|5763945|CAB53324.1|AL109974 probable
                     iron-siderophore binding lipoprotein from Streptomyces
                     coelicolor (350 aa); and (N-terminus may be incorrect) to
                     T14166|3560508|AAC82551.1|AF027770 fxuD protein from
                     Mycobacterium smegmatis (420 aa). Also similar to
                     AAB97475.1|U02617 DtxR/iron regulated lipoprotein
                     precursor from Corynebacterium diphtheriae (355 aa);
                     FECB_ECOLI|P15028 iron(III) dicitrate-binding periplasmic
                     protein (300 aa). Contains PS00013 Prokaryotic membrane
                     lipoprotein lipid attachment site. Note that previously
                     known as fecB2."
                     /codon_start=1
                     /transl_table=11
                     /product="putative periplasmic iron-transport lipoprotein"
                     /protein_id="AJF01615.1"
                     /db_xref="GOA:Q7DA51"
                     /db_xref="InterPro:IPR002491"
                     /db_xref="InterPro:IPR006311"
                     /db_xref="UniProtKB/TrEMBL:Q7DA51"
                     /translation="MRQGCSRRGFLQVAEAAAATGLFAGCSSPKPPPGTPGGAAVTIT
                     HLFGQTVIKEPPKRVVSAGYTEQDDLLAVDVVPIAVTDWFGDQPFAVWPWAAPKLGGA
                     RPAVLNLDNGIQIDRIAALKPDLIVAINAGVDADTYQQLSAIAPTVAQSGGDAFFEPW
                     KDQARSIGQAVFAADRMRSLIEAVDQKFAAVAQRHPRWRGKKALLLQGRLWQGNVVAT
                     LAGWRTDFLNDMGLVIADSIKPFAVDQRGVIPRDHIKAVLDAADVLIWMTESPEDEKA
                     LLADPEIAASQATAQRRHIFTSKEQAGAIAFSSVLSYPVVAEQLPPQISQILGA"
     gene            complement(317525..321154)
                     /gene="oplA"
                     /locus_tag="Y980_0266c"
     CDS             complement(317525..321154)
                     /gene="oplA"
                     /locus_tag="Y980_0266c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0266c, (MTCY06A4.10c) Probable oplA,
                     5-oxoprolinase, highly similar to others or to
                     hypothetical proteins e.g. AAK24340.1|AE005906
                     hydantoinase/oxoprolinase from Caulobacter crescentus
                     (1196 aa); NP_103129.1|14022305|BAB48915.1|AP002997
                     5-oxoprolinase from Mesorhizobium loti (1210 aa);
                     CAC48426.1|AL603642 conserved hypothetical protein from
                     Sinorhizobium meliloti (1205 aa);
                     S77037|slr0697|1006579|BAA10729.1|D6400 hypothetical
                     protein from Synechocystis sp. strain PCC 6803 (1252 aa);
                     P97608|OPLA_RAT|T42756|11278797 5-oxoprolinase
                     (5-oxo-L-prolinase) (pyroglutamase) (5-OPASE) from Rattus
                     norvegicus (1288 aa); etc. Belongs to the oxoprolinase
                     family."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 5-oxoprolinase OplA (5-oxo-L-prolinase)
                     (pyroglutamase) (5-OPASE)"
                     /protein_id="AJF01616.1"
                     /db_xref="GOA:L0T352"
                     /db_xref="InterPro:IPR002821"
                     /db_xref="InterPro:IPR003692"
                     /db_xref="InterPro:IPR008040"
                     /db_xref="UniProtKB/TrEMBL:L0T352"
                     /translation="MVGAGWHFWVDRGGTFTDVVARRPDGRLLTHKLLSDNPARYRDA
                     AVAGIRALLANGEAGTRVDAVRMGTTVATNALLERTGERTLLVITRGFGDALRIAYQN
                     RPRIFDRRIVLPEMLYERVVEVDERVTADGRVLRAPDLEALGEKMRQAHADGIRAVAV
                     VCLHSYLYPGHEREIGTLAQRIGFAQISLSSEVSPLMKLVPRGDTTVVDAYLSPVLRR
                     YINQVADQMRGVRLMFMQSNGGLAQAGHFRGKDAILSGPAGGIVGMVRMSALAGFDHV
                     IGFDMGGTSTDVSHYAGEYERVFTTQVAGVRLRAPMLDIHTVAAGGGSILHFDGSRYR
                     VGPDSAGADPGPACYRGGGPLCVTDANVMLGRIQPTHFPSVFGPSGDQPLDAGTVRRG
                     FTDLAADIAARTGDDRSPEQVAEGYLRIAVANMANAVKKISVQKGHDVTRYALTTFGG
                     AGGQHACAVADALGIRTVLIPPMAGVLSALGIGLADTTAMREQSVEIPLGPAAPQRLA
                     SVAESLERAARAELLDEGVPGERIRVVRRVHLRYEGTDTAIPVQLAEIETMATAFESS
                     HRALYTFLLDRPLIAEAISVEATGLTDQPDLSQLGDQANDTTGSSETVRIYSNGLWRD
                     APLRRREAMRPGDVLTGPAIIAEANATTVVDDGWQATMTETGHLLAQRVVTPPRPDAA
                     TRAGFEAGFEADPVLLEIFNNLFMSIAEQMGFRLEATAQSVNIRERLDFSCALFDPDG
                     NLVANAPHIPVHLGSMGTTVKEVIRRRLSGMKPGDVYAVNDPYHGGTHLPDITVITPV
                     FNTGGEDVLFFVASRGHHAEIGGITPGSMPADSREIHEEGVLFDNWLLAENGRFREAE
                     TRRLLTEAPFGSRNPDTNLADLRAQIAANQKGVDEVGKMIDHFGRDVVAAYMRHVQDN
                     AEEAVRRVIDRLDNGAYRYRMDSGATIAVRITVDRAARSATIDFTGTSAQLDTNFNAP
                     TSVVNAAVLYVFRTLVADDIPLNDGCLRPLRIVVPEGSMLAPTHPAAVVAGNVETSQA
                     ITGALFAALGVQAEGSGTMNNVTFGNERHQYYETVGSGSGAGDGYHGASVVQTHMTNS
                     RLTDPEVLEWRYPVLLREFAVRQGSGGAGRWRGGDGAVRRLEFTEPMTVSTLSGHRRV
                     RPYGMAGGSPGELGRNRVERADGSTVELAGCGSTHVEPGDTLVIETPGGGGYGPASTS
                     ARRRR"
     gene            321331..322722
                     /gene="narU"
                     /locus_tag="Y980_0267"
     CDS             321331..322722
                     /gene="narU"
                     /locus_tag="Y980_0267"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0267, (MTCY06A4.11) Probable narU,nitrite
                     extrusion protein, integral membrane protein possibly
                     member of major facilitator superfamily (MFS),similar to
                     other nitrite extrusion proteins e.g. NARU_ECOLI|P37758
                     nitrite extrusion protein 2 from Escherichia coli (462
                     aa); and NARK_ECOLI|P10903|B1223 nitrite extrusion protein
                     1 from Escherichia coli strain K12 (463 aa). Also similar
                     to Rv0261c, Rv2329c, Rv1737c, and to MLCB22_25 from
                     Mycobacterium leprae (517 aa). Belongs to the nark/NASA
                     family of transporters."
                     /codon_start=1
                     /transl_table=11
                     /product="putative integral membrane nitrite extrusion
                     protein NarU (nitrite facilitator)"
                     /protein_id="AJF01617.1"
                     /db_xref="GOA:L7N5I5"
                     /db_xref="InterPro:IPR004737"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="UniProtKB/TrEMBL:L7N5I5"
                     /translation="MALTTAPAIDYALPRQQDEGDHWIDDWRPEDPVFWETIGRPIAR
                     RNLIFSIFAEHVGFSVWMLWSIVVVQMTAAAPGHPAASGWALSASQALCLVAVPSGVG
                     AFLRLPYTFAIPIFGGRNWTTVSAALLVIPCLLLAWAVSHPSLPFAVLVVIAATAGFG
                     GGNFASSMANISFFYPEKDKGWALGLNAAGGNIGVAVVQKIIPPIVVAGSGVALSRAG
                     LFFVPLAVAAAVCAFLFMNNLTEAKADVKPVWQSLRHADTWIMSLLYIGTFGSFIGYS
                     AAFPTLLKTVFGRGDIALGWAFLGAGIGSLVRPLGGKLADRIGGARITAASFVMLAAG
                     AAAALWSVQSVNLPVFFVSFMFLFVATGIGNGSSYRMISRIFQVKGEVAGGDPETMVN
                     MRRQAAGALGIISSIGAFGGFVVPLAYAWSKVHFGNIEPALHFYVAFFLALLVVTWYC
                     YLRRTTPMGQVGV"
     gene            complement(322764..323273)
                     /locus_tag="Y980_0268c"
     CDS             complement(322764..323273)
                     /locus_tag="Y980_0268c"
                     /note="Rv0268c, (MTCY06A4.12c) Hypothetical unknown
                     protein."
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /protein_id="AJF01618.1"
                     /db_xref="InterPro:IPR006442"
                     /db_xref="UniProtKB/TrEMBL:L7N569"
                     /translation="MGTRSKSRTRQLKQSNGCTATTSGASDRRRRARRRTAPAWLRED
                     EWLRHHLPHPPRQLSRCLHRRRRSACHHRYSRRTPKGGLPMTSSLVPISEARAHLSRL
                     VRESADDDVVLMNHGRPAAILISAERYESLMEELEDLRDRLSVHEREHVTMPLDKLGA
                     ELGVDIGRV"
     gene            complement(323338..324531)
                     /locus_tag="Y980_0269c"
     CDS             complement(323338..324531)
                     /locus_tag="Y980_0269c"
                     /note="Rv0269c, (MTCY06A4.13c) Conserved hypothetical
                     protein, highly similar to AL079355|SC4C6_19 hypothetical
                     protein from Streptomyces coelicolor (341 aa), and similar
                     to other proteins e.g. CAC49016.1|AL603644 putative
                     ATP-dependent DNA ligase protein from Sinorhizobium
                     meliloti (636 aa); O34398 YKOU protein from Bacillus
                     subtilis (611 aa). Also similar to proteins from
                     Mycobacterium tuberculosis e.g. Rv3062,Rv3731 (both DNA
                     ligases), and Rv0938, Rv3730c."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01619.1"
                     /db_xref="GOA:L0T4V5"
                     /db_xref="InterPro:IPR002755"
                     /db_xref="UniProtKB/TrEMBL:L0T4V5"
                     /translation="MSRMAAPVSLDVHGRQVIVTHPGRVVFPAHNDRKGYTKFDLVRY
                     YLAVAEGAMRGVAGRPMILKRFVKGISAEAVFQKRAPANRPDWVDVAELHYASGRSAA
                     EAVIHDAAGLAWVINLGCVDLNPHPVLAGDLDHPDELRVDLDPMPGVAWQRVVEVALV
                     VREVLEDYGLTAWPKTSGSRGFHVYARIAPCWSFPQVRLAAQTVAREVERRLPDAATS
                     RWWKEEREGVFVDFNQNAKDRTVASAYSVRATPDARVSTPLHWEEVPGCDPAVFTMAT
                     VPSRLADIGDPWAGMDDAVGRLDRLLMLAEELGPPQKAQSAKPLIEIARAKTRAEAMA
                     ALDIWRDRYPGAAALLRPADVLVDGMRGPSSIWYRIRINLQHVPADQRPPQEELIADY
                     SPWPR"
     gene            324567..326249
                     /gene="fadD2"
                     /locus_tag="Y980_0270"
     CDS             324567..326249
                     /gene="fadD2"
                     /locus_tag="Y980_0270"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00455"
                     /note="Rv0270, (MTCY06A4.14) Probable fadD2,fatty-acid-CoA
                     synthetase, similar to many e.g. LCFA_ECOLI|P29212
                     long-chain-fatty-acid--CoA ligase from Escherichia coli
                     (561 aa). Also similar to others from Mycobacterium
                     tuberculosis e.g. MTCY493_2,MTCY8D5_9, MTCY6G11_8, etc.
                     Contains PS00455 Putative AMP-binding domain signature."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fatty-acid-CoA ligase FadD2
                     (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)"
                     /protein_id="AJF01620.1"
                     /db_xref="GOA:L7N5E5"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="UniProtKB/TrEMBL:L7N5E5"
                     /translation="MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGL
                     EPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANG
                     LLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAK
                     VIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKAS
                     RRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYM
                     HAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDL
                     SSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGP
                     VVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFD
                     ERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFV
                     VKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELRKL"
     gene            complement(326266..328461)
                     /gene="fadE6"
                     /locus_tag="Y980_0271c"
     CDS             complement(326266..328461)
                     /gene="fadE6"
                     /locus_tag="Y980_0271c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0271c, (MTCY06A4.15c) Probable fadE6, acyl-CoA
                     dehydrogenase, with C-terminal half similar to many e.g.
                     ACDS_HUMAN|P16219 acyl-CoA dehydrogenase (short-chain)
                     from Homo sapiens (412 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA dehydrogenase FadE6"
                     /protein_id="AJF01621.1"
                     /db_xref="GOA:L7N5P6"
                     /db_xref="InterPro:IPR006090"
                     /db_xref="InterPro:IPR006091"
                     /db_xref="InterPro:IPR006092"
                     /db_xref="InterPro:IPR009075"
                     /db_xref="InterPro:IPR009100"
                     /db_xref="InterPro:IPR013786"
                     /db_xref="UniProtKB/TrEMBL:L7N5P6"
                     /translation="MSIAITPEHYELADSVRSLVARVAPSEVLHAALESPVENPPPYW
                     QAAAEQGLQGVHLAESVGGQGFGILELAVVLAEFGYGAVPGPFVPSAIASALIAAHDP
                     QAKVLAELATGAAIAAYALDSGLTATRHGDVLVIRGEVRAVPAAAQASVLVLPVAIES
                     RDEWVVLRNDQLEIEAVKSLDPLRPIAHVRANAVDVSDDALLSNLTMTTAHALMSTLL
                     SAEAVGVARWATDTASAYAKIREQFGRPIGQFQAIKHKCAEMIADTERATAAVWDAAR
                     ALDDAGESSSDVEFAAAVAATLAPATAQRCTQDCIQVHGGIGFTWEHDTNVYYRRALM
                     LAACFGRGSEYPQRVVDTATTAGMRPVDIDLDPSTEKLRAQIRAEVAALKAMPREPRT
                     VAIAEGGWVLPYLPKPWGRAASPVEQIIIAQEFTAGRVKRPQIAIATWIVPSIVAFGT
                     DNQKQRLLPPTFRGDIFWCQLFSEPGAGSDLASLATKATRVDGGWRITGQKIWTTGAQ
                     YSQWGALLARTDPSAPKHNGITYFLLDMKSEGVQVKPLRELTGKEFFNTVYLDDVFVP
                     DELVLGEVNRGWEVSRNTLTAERVSIGGSDSTFLPTLGEFVDFVRDYRFEGQFDQVAR
                     HRAGQLIAEGHATKLLNLRSTLLTLAGGDPMAPAAISKLLSMRTGQGYAEFAVSSFGT
                     DAVIGDTERLPGKWGEYLLASRATTIYGGTSEVQLNIIAERLLGLPRDP"
     gene            complement(328575..329708)
                     /locus_tag="Y980_0272c"
     CDS             complement(328575..329708)
                     /locus_tag="Y980_0272c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0272c, (MTCY06A4.16c) Unknown protein."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01622.1"
                     /db_xref="UniProtKB/TrEMBL:L0T667"
                     /translation="MTGRAATPGVIREFVGLPSRTAGRAAAGGHPCQGLYHHSVGRKP
                     KVALIAAHYQIDFSEHYLAEYMAIRGIGFLGWNTRFRGFESSFLLDHALVDIGVGVRW
                     LREVQGVETVVLLGNSGGGSLMAAYQSQAVDPNVTPLDGMRPAAGVTELPAADAYVAA
                     AAHPGRPDVLTAWMDAAVIDENDPVATDPELDLFDERNGPPYSPEFISRYRSAQVKRN
                     HTITDWAESELKRVRAAGFSDRPFSVMRTWADPRMVDPSIEPTKRRPNQCYAGTPVKA
                     NRSAHGIAAACTLRGWLGMWSLRVAQTRAAPHLARITCPALVLNAEADTGIFPSDAQQ
                     IYDGLASSDKTQVSIDTDHYFTTPGARSEQADTIAKWIAKRWR"
     gene            complement(329705..330325)
                     /locus_tag="Y980_0273c"
     CDS             complement(329705..330325)
                     /locus_tag="Y980_0273c"
                     /note="Rv0273c, (MTV035.01c), len: 206 aa (start
                     uncertain). Possible transcriptional regulator, showing
                     some similarity to hypothetical regulators from
                     Mycobacterium tuberculosis e.g. P96222|Rv3855|MTCY01A6.13c
                     (216 aa); O08377|Rv1534|MTCY07A7A.03 (225 aa)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein"
                     /protein_id="AJF01623.1"
                     /db_xref="GOA:L7N4S4"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR011075"
                     /db_xref="InterPro:IPR015893"
                     /db_xref="UniProtKB/TrEMBL:L7N4S4"
                     /translation="MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRS
                     AASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNR
                     LAEAISVSQLAMVSDDFAQYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIV
                     AMFNQFCYLQLSGKRSRRGQPDDQACIQTLANIYYRAIYSKEDSSN"
     gene            330422..331003
                     /locus_tag="Y980_0274"
     CDS             330422..331003
                     /locus_tag="Y980_0274"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00082"
                     /note="Rv0274, (MTV035.02) Conserved protein,highly
                     similar to AAK25058.1|AE005973 conserved hypothetical
                     protein from Caulobacter crescentus (174 aa). Shows also
                     some similarity to others hypothetical proteins e.g.
                     AJ002571|BSAJ2571_7 from Bacillus subtilis (316 aa).
                     Previous hits with Q56415|M85195 fosfomycin-resistance
                     protein from serratia marcescens (141 aa). Contains
                     PS00082 Extradiol ring-cleavage dioxygenases signature
                     near C-terminus. May belong to the vicinal-oxygen-chelate
                     (VOC) superfamily of metalloenzymes (See Rawat et al.,
                     2003)."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AJF01624.1"
                     /db_xref="GOA:L0T4W2"
                     /db_xref="InterPro:IPR000486"
                     /db_xref="InterPro:IPR004360"
                     /db_xref="UniProtKB/TrEMBL:L0T4W2"
                     /translation="MIKPHNTNTEFELGGINHVALVCSDMARTVDFYSNILGMPLIKA
                     LDLPGGQGQHFFFDAGNGDCVAFFWFADAPDRVPGLSSPVAIPGIGDITSAVSTMNHL
                     AFHVPAERFDAYRQRLKDKGVRVGPVLNHDDSETQVSAVVHPGVYVRSFYFQDPDGIT
                     LEFACWTKEFTTSDAQAVPKTAADRRPPVAADR"
     gene            complement(330933..331658)
                     /locus_tag="Y980_0275c"
     CDS             complement(330933..331658)
                     /locus_tag="Y980_0275c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /note="Rv0275c, (MTV035.03c) Possible transcriptional
                     regulator, TetR family, similar to others e.g.
                     Q9RJE7|SCF81.04c putative TetR-family transcriptional
                     regulator from Streptomyces coelicolor (219 aa);
                     Q9FBI8|SCP8.33c putative TetR-family transcriptional
                     regulator from Streptomyces coelicolor (213 aa);
                     Q9I2Q9|PA1836 probable transcriptional regulator from
                     Pseudomonas aeruginosa (193 aa); etc. Also shows some
                     similarity with Rv0825c from Mycobacterium tuberculosis
                     (213 aa). Seems to belong to the TetR/AcrR family of
                     transcriptional regulators (M. tuberculosis regulatory
                     protein family with many TetR orthologues)."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulatory protein
                     (possibly TetR-family)"
                     /pro