LOCUS BK006944 666816 bp DNA linear PLN 12-APR-2024
DEFINITION TPA_inf: Saccharomyces cerevisiae S288C chromosome XI, complete
sequence.
ACCESSION BK006944
VERSION BK006944.2
DBLINK BioProject: PRJNA43747
KEYWORDS Third Party Data; TPA; TPA:inferential.
SOURCE Saccharomyces cerevisiae S288C
ORGANISM Saccharomyces cerevisiae S288C
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (bases 1 to 666816)
AUTHORS Dujon,B., Alexandraki,D., Andre,B., Ansorge,W., Baladron,V.,
Ballesta,J.P., Banrevi,A., Bolle,P.A., Bolotin-Fukuhara,M.,
Bossier,P. et al.
TITLE Complete DNA sequence of yeast chromosome XI
JOURNAL Nature 369 (6479), 371-378 (1994)
PUBMED 8196765
REFERENCE 2 (bases 1 to 666816)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 3 (bases 1 to 666816)
AUTHORS Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
Weng,S. and Cherry,J.M.
TITLE New data and collaborations at the Saccharomyces Genome Database:
updated reference genome, alleles, and the Alliance of Genome
Resources
JOURNAL Genetics 220 (4) (2022)
PUBMED 34897464
REFERENCE 4 (bases 1 to 666816)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (14-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REFERENCE 5 (bases 1 to 666816)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 6 (bases 1 to 666816)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
COMMENT THIRD PARTY DATABASE: This TPA record uses data from
DDBJ/EMBL/GenBank entries JF740677.1, Z28001.1, Z28002.1, Z28003.1,
Z28004.1, Z28005.1, Z28006.1, Z28007.1, Z28008.1, Z28009.1,
Z28010.1, Z28011.1, Z28012.1, Z28013.1, Z28014.1, Z28015.1,
Z28016.1, Z28017.1, Z28018.1, Z28019.1, Z28020.1, Z28021.1,
Z28022.1, Z28023.1, Z28024.1, Z28025.1, Z28026.1, Z28027.1,
Z28028.1, Z28029.1, Z28031.1, Z28032.1, Z28033.1, Z28034.1,
Z28035.1, Z28038.1, Z28039.1, Z28040.1, Z28041.1, Z28042.1,
Z28043.1, Z28044.1, Z28045.1, Z28046.1, Z28047.1, Z28048.1,
Z28049.1, Z28050.1, Z28051.1, Z28052.1, Z28054.1, Z28055.1,
Z28056.1, Z28057.1, Z28058.1, Z28059.1, Z28060.1, Z28061.1,
Z28062.1, Z28063.1, Z28064.1, Z28065.1, Z28066.1, Z28067.1,
Z28068.1, Z28069.1, Z28070.1, Z28071.1, Z28072.1, Z28073.1,
Z28074.1, Z28075.1, Z28077.1, Z28078.1, Z28079.1, Z28080.1,
Z28081.1, Z28082.1, Z28084.1, Z28085.1, Z28086.1, Z28087.1,
Z28088.1, Z28089.1, Z28090.1, Z28091.1, Z28092.1, Z28093.1,
Z28094.1, Z28095.1, Z28096.1, Z28097.1, Z28098.1, Z28099.1,
Z28100.1, Z28101.1, Z28102.1, Z28103.1, Z28104.1, Z28105.1,
Z28106.1, Z28107.1, Z28108.1, Z28109.1, Z28110.1, Z28111.1,
Z28113.1, Z28114.1, Z28115.1, Z28117.1, Z28118.1, Z28120.1,
Z28121.1, Z28122.1, Z28123.1, Z28125.1, Z28126.1, Z28127.1,
Z28128.1, Z28129.1, Z28130.1, Z28131.1, Z28133.1, Z28134.1,
Z28135.1, Z28137.1, Z28138.1, Z28139.1, Z28140.1, Z28141.1,
Z28142.1, Z28143.1, Z28144.1, Z28145.1, Z28146.1, Z28148.1,
Z28149.1, Z28150.1, Z28151.1, Z28152.1, Z28154.1, Z28155.1,
Z28156.1, Z28157.1, Z28158.1, Z28159.1, Z28160.1, Z28161.1,
Z28162.1, Z28163.1, Z28164.1, Z28165.1, Z28166.1, Z28167.1,
Z28168.1, Z28169.1, Z28171.1, Z28172.1, Z28173.1, Z28174.1,
Z28175.1, Z28176.1, Z28177.1, Z28179.1, Z28180.1, Z28181.1,
Z28182.1, Z28183.1, Z28184.1, Z28185.1, Z28186.1, Z28187.1,
Z28188.1, Z28189.1, Z28190.1, Z28191.1, Z28192.1, Z28193.1,
Z28194.1, Z28195.1, Z28196.1, Z28197.1, Z28198.1, Z28200.1,
Z28201.1, Z28202.1, Z28203.1, Z28204.1, Z28205.1, Z28206.1,
Z28207.1, Z28208.1, Z28209.1, Z28210.1, Z28211.1, Z28212.1,
Z28213.1, Z28214.1, Z28215.1, Z28216.1, Z28217.1, Z28218.1,
Z28219.1, Z28220.1, Z28221.1, Z28222.1, Z28223.1, Z28224.1,
Z28225.1, Z28226.1, Z28227.1, Z28228.1, Z28229.1, Z28230.1,
Z28231.1, Z28232.1, Z28233.1, Z28234.1, Z28235.1, Z28236.1,
Z28237.1, Z28238.1, Z28239.1, Z28240.1, Z28241.1, Z28242.1,
Z28243.1, Z28244.1, Z28245.1, Z28246.1, Z28247.1, Z28248.1,
Z28249.1, Z28250.1, Z28251.1, Z28252.1, Z28253.1, Z28254.1,
Z28255.1, Z28256.1, Z28257.1, Z28258.1, Z28259.1, Z28260.1,
Z28261.1, Z28262.1, Z28263.1, Z28264.1, Z28265.1, Z28266.1,
Z28267.1, Z28268.1, Z28269.1, Z28270.1, Z28271.1, Z28272.1,
Z28273.1, Z28274.1, Z28275.1, Z28276.1, Z28277.1, Z28278.1,
Z28279.1, Z28280.1, Z28281.1, Z28282.1, Z28283.1, Z28284.1,
Z28285.1, Z28286.1, Z28287.1, Z28288.1, Z28289.1, Z28290.1,
Z28291.1, Z28292.1, Z28293.1, Z28294.1, Z28295.1, Z28296.1,
Z28297.1, Z28298.1, Z28299.1, Z28300.1, Z28301.1, Z28302.1,
Z28303.1, Z28304.1, Z28305.1, Z28306.1, Z28307.1, Z28308.1,
Z28309.1, Z28310.1, Z28311.1, Z28312.1, Z28313.1, Z28314.1,
Z28315.1, Z28316.1, Z28317.1, Z28318.1, Z28319.1, Z28320.1,
Z28321.1, Z28322.1, Z28323.1, Z28324.1, Z28325.1, Z28326.1,
Z28327.1, Z28328.1, Z28329.1 and Z28330.1
On Apr 18, 2011 this sequence version replaced BK006944.1.
Chromosome XI sequence was verified by resequencing. The sequence
was mapped to the previous GenBank records except for a 500 bp
region. That region was determined by sequencing a descendant of
the S288C strain, AB972, and is present in GenBank as JF740677.
##Genome-Annotation-Data-START##
Annotation Provider :: SGD
Annotation Status :: Full Annotation
Annotation Version :: R64-4-1
URL :: http://www.yeastgenome.org/
##Genome-Annotation-Data-END##
FEATURES Location/Qualifiers
source 1..666816
/organism="Saccharomyces cerevisiae S288C"
/mol_type="genomic DNA"
/strain="S288C"
/db_xref="taxon:559292"
/chromosome="XI"
telomere complement(1..807)
/note="TEL11L; Telomeric region on the left arm of
Chromosome XI; composed of an X element core sequence, X
element combinatorial repeats, and a short terminal
stretch of telomeric repeats"
/db_xref="SGD:S000028906"
gene complement(1810..2181)
/gene="PAU16"
/locus_tag="YKL224C"
mRNA complement(1810..2181)
/gene="PAU16"
/locus_tag="YKL224C"
/product="seripauperin PAU16"
CDS complement(1810..2181)
/gene="PAU16"
/locus_tag="YKL224C"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:26928762]"
/note="hypothetical protein; member of the seripauperin
multigene family encoded mainly in subtelomeric regions;
SWAT-GFP and mCherry fusion proteins localize to the
vacuole"
/codon_start=1
/product="seripauperin PAU16"
/protein_id="DAA08946.1"
/db_xref="SGD:S000001707"
/translation="MVKLTSIAAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVS
DIRAHLAQYYLFQAAHPSETYPVEIAEAVFNYGDFTTMLTGIPAEQVTRVITGVPWYS
TRLRPAISSALSKDGIYTIAN"
gene complement(3503..5620)
/locus_tag="YKL222C"
mRNA complement(3503..5620)
/locus_tag="YKL222C"
/product="hypothetical protein"
CDS complement(3503..5620)
/locus_tag="YKL222C"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:21777356]"
/experiment="EXISTENCE:direct assay:GO:0043565
sequence-specific DNA binding [PMID:19158363]"
/experiment="EXISTENCE:direct assay:GO:0072686 mitotic
spindle [PMID:21777356]"
/note="hypothetical protein; may interact with ribosomes,
based on co-purification experiments; similar to
transcriptional regulators from the zinc cluster
(binuclear cluster) family; null mutant is sensitive to
caffeine"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA08947.1"
/db_xref="SGD:S000001705"
/translation="MKNTELSQKKKLDRQSRRKPAKSCHFCRVRKLKCDRVRPFCGSC
SSRNRKQCEYKENTSAMEDQLRKKYRRCSKLEMARRIEELESQLTKQSQPNIHEGQNP
LSNMRYLSSKHNRHILYGPTSYRAILATQTDTFAKYREEIWQVLKLSRNNWKREHHYS
TLSEISSIETAPPHSGSPSVIEYLCESLPNYEVLCEYLTDFFASDFYDSYQIVHKEKV
LRDLQDCFVKGPRSHKTGQHTIISLNLDSKKNYYKVGVMTAIMCLASHPKEVPEAIEV
FHKVLTSFVSAKVFYTERVQFLFLRYLYINVAGLDGGDQSHCIFIHGLTIDTAIHMGL
NEDLRRLYLSKNHPIEEIPYLERLWLWILFTDVKISLSTGIPVRINDDFVNKVRLENY
SSSGDILLYKTTLRLRNIMKQIHAREKPPDIPLIIEDLKKFTIKMFKPLDFYLNASNL
NGNEFTELQLWHATLHMIGSLSNLYTLTHQDFDARIFNFSVLAPLNSLHLCFNVLETY
FELDNSKLSSKSLCLSKKWPHLNNALFLIYVNAFRALIQIYTIFLQYMENKDIQLFIQ
RNSSALTYSICPGDFEGPHNKCISLKIAFKEMENIFDHIHQEKLKPLTQIWQNSYYFS
IIISMEKIGRRAFNKGMKNIDEGPETENDATENSLTTILNDLEGPLEDFSENFIDDIL
GSPSAFFDTAISGWSNFEDFFSR"
gene 6107..7528
/gene="MCH2"
/locus_tag="YKL221W"
mRNA 6107..7528
/gene="MCH2"
/locus_tag="YKL221W"
/product="Mch2p"
CDS 6107..7528
/gene="MCH2"
/locus_tag="YKL221W"
/note="Protein with similarity to mammalian
monocarboxylate permeases; monocarboxylate permeases are
involved in transport of monocarboxylic acids across the
plasma membrane but mutant is not deficient in
monocarboxylate transport"
/codon_start=1
/product="Mch2p"
/protein_id="DAA08948.2"
/db_xref="SGD:S000001704"
/translation="MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFI
LLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVIT
WLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLI
PLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCIICTSLSTIAL
MLTRTTHQGLRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTV
SLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHLVMAILCWAMWIPC
KNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPII
GLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNEL
HLNVKLSHMSKCLFRYKQLPRRV"
rep_origin 7528..8309
/note="ARS1102; Putative replication origin; identified in
multiple array studies, not yet confirmed by plasmid-based
assay"
/db_xref="SGD:S000130137"
gene complement(9091..11226)
/gene="FRE2"
/locus_tag="YKL220C"
mRNA complement(9091..11226)
/gene="FRE2"
/locus_tag="YKL220C"
/product="ferric/cupric-chelate reductase"
CDS complement(9091..11226)
/gene="FRE2"
/locus_tag="YKL220C"
/EC_number="1.16.1.9"
/experiment="EXISTENCE:direct assay:GO:0000184
nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay [PMID:31322728]"
/experiment="EXISTENCE:direct assay:GO:0000293
ferric-chelate reductase activity [PMID:8164662]"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:8164662]"
/experiment="EXISTENCE:direct assay:GO:0006826 iron ion
transport [PMID:8164662]"
/experiment="EXISTENCE:direct assay:GO:0015677 copper ion
import [PMID:9153234]"
/note="Ferric reductase and cupric reductase; reduces
siderophore-bound iron and oxidized copper prior to uptake
by transporters; expression induced by low iron levels but
not by low copper levels"
/codon_start=1
/product="ferric/cupric-chelate reductase"
/protein_id="DAA08949.1"
/db_xref="SGD:S000001703"
/translation="MHWTSILSAILLFCLSGARASPAKTVIRNKVPLLVTNACTRIFQ
KVTWEYTSKSKRSSPVCSYEPAFQSMLYCIYETLDEKGYSNKTLEKTFSTIKKNCASY
SDALQNMTNSEFYDVLNNGTRHMTPYVKGSANLTYPVEMDTQLRKAYYHALHGFYANL
DVGNIYGGIICAYFVAIMAFAGVLHCMNYTPFKTVLLKQKLVGYVRGYLTLPTIGSKH
ASDFSYFRIFTGYLPTRLEGIIILGYLVLHTVFLAYGYEYDPENIIFKSRRVQVARYV
ADRSGVLAFAHFPLIVLFAGRNNFLEYISGVKYTSFIMFHKWLGRMMFLDAMIHGSAY
TSYTVANKTWATSKNRLYWQFGVAALCLAGTMVFFSFAVFRKYFYEAFLFLHIVLGAM
FFYACWEHVVSLSGIEWIYTAIAIWIVDRIIRIIKASYFGFPKASLQLIGDDLIRLTV
KKPARPWRAKPGQYVFVSFLHPLYFWQSHPFTVLDSVSKNGELVIILKEKKGVTRLVK
KYVCRNGGKTSMRLAIEGPYGSSSPVNNYNNVLLLTGGTGLPGPIAHAIKLGKTSAAA
GKQSVKLVIAVRGFDVLEAYKPELMCLENLNVQLHIYNTMEVPSLTPSDSLDISQQDE
KADEKGTVVATTLEKSANPLGFDGVVFHCGRPNVKELLHEAAELSGSLSVVCCGPPIF
VDKVRNETAKIVLDKSAKAIEYFEEYQCW"
gene 14485..15708
/gene="COS9"
/locus_tag="YKL219W"
mRNA 14485..15708
/gene="COS9"
/locus_tag="YKL219W"
/product="Cos9p"
CDS 14485..15708
/gene="COS9"
/locus_tag="YKL219W"
/note="Endosomal protein involved in turnover of plasma
membrane proteins; member of the DUP380 subfamily of
conserved, often subtelomeric COS genes; required for the
multivesicular vesicle body sorting pathway that
internalizes plasma membrane proteins for degradation; Cos
proteins provide ubiquitin in trans for nonubiquitinated
cargo proteins"
/codon_start=1
/product="Cos9p"
/protein_id="DAA08950.1"
/db_xref="SGD:S000001702"
/translation="MQIVRSCNSNNKPLIPSSNWHIAIRMRGDGVKDRSIDVLSLKHF
ESQKVVLPQDLFMDNFTWMFYEFFKCFTFRTWLLLLLLMWLPGFLSQIKSINRIFPFK
LCILVSCLVGIFLPNIYSFSHKSVLTNQLTQFSKEIVEHAPGTDTHDWETVAANLNSY
FYENKAWNTEYFFFNAAECQKAFRKVLLEPFSVKKDESSKIKSFGDSVPYIEEALQVY
STEFDKKWKLFNTEKVWSPDNLEHVQLPKKTYRYKFTWVLKRIFNLWLFPAFILFLAC
IYVSWDKGHLFRILCCGGGFLLMVRVFQNMRPFSMHMEDKMQFLSTIINEQESGANGW
DEIAKKMNRYLFEKKVWTSEEFFFDGIDCEWFFNHFFYRLLSTKKPMFDRPLNVELWP
YIKEAQLTRKQAPPV"
gene complement(17359..18339)
/gene="SRY1"
/locus_tag="YKL218C"
mRNA complement(17359..18339)
/gene="SRY1"
/locus_tag="YKL218C"
/product="threo-3-hydroxy-L-aspartate ammonia-lyase SRY1"
CDS complement(17359..18339)
/gene="SRY1"
/locus_tag="YKL218C"
/EC_number="4.3.1.16"
/experiment="EXISTENCE:direct assay:GO:0030848
threo-3-hydroxyaspartate ammonia-lyase activity
[PMID:12951240]"
/experiment="EXISTENCE:direct assay:GO:0042219 cellular
modified amino acid catabolic process [PMID:12951240]"
/experiment="EXISTENCE:mutant phenotype:GO:0030848
threo-3-hydroxyaspartate ammonia-lyase activity
[PMID:12951240]"
/experiment="EXISTENCE:mutant phenotype:GO:0042219
cellular modified amino acid catabolic process
[PMID:12951240]"
/note="3-hydroxyaspartate dehydratase; deaminates
L-threo-3-hydroxyaspartate to form oxaloacetate and
ammonia; required in the presence of hydroxyaspartate;
highly similar to mouse serine racemase (Srr) but has no
serine racemase activity"
/codon_start=1
/product="threo-3-hydroxy-L-aspartate ammonia-lyase SRY1"
/protein_id="DAA08951.1"
/db_xref="SGD:S000001701"
/translation="MIVPTYGDVLDASNRIKEYVNKTPVLTSRMLNDRLGAQIYFKGE
NFQRVGAFKFRGAMNAVSKLSDEKRSKGVIAFSSGNHAQAIALSAKLLNVPATIVMPE
DAPALKVAATAGYGAHIIRYNRYTEDREQIGRQLAAEHGFALIPPYDHPDVIAGQGTS
AKELLEEVGQLDALFVPLGGGGLLSGSALAARSLSPGCKIFGVEPEAGNDGQQSFRSG
SIVHINTPKTIADGAQTQHLGEYTFAIIRENVDDILTVSDQELVKCMHFLAERMKVVV
EPTACLGFAGALLKKEELVGKKVGIILSGGNVDMKRYATLISGKEDGPTI"
gene 22234..24084
/gene="JEN1"
/locus_tag="YKL217W"
mRNA 22234..24084
/gene="JEN1"
/locus_tag="YKL217W"
/product="monocarboxylate/H+ symporter"
CDS 22234..24084
/gene="JEN1"
/locus_tag="YKL217W"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:17710650]"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/experiment="EXISTENCE:mutant phenotype:GO:0006849 plasma
membrane pyruvate transport [PMID:17710650]"
/experiment="EXISTENCE:mutant phenotype:GO:0015355
secondary active monocarboxylate transmembrane transporter
activity [PMID:17710650]"
/experiment="EXISTENCE:mutant phenotype:GO:0035879 plasma
membrane lactate transport [PMID:10198029|PMID:17710650]"
/experiment="EXISTENCE:mutant phenotype:GO:0097079
selenite:proton symporter activity [PMID:20861301]"
/experiment="EXISTENCE:mutant phenotype:GO:0097080 plasma
membrane selenite transport [PMID:20861301]"
/note="Monocarboxylate/proton symporter of the plasma
membrane; transport activity is dependent on the pH
gradient across the membrane; mediates high-affinity
uptake of carbon sources lactate, pyuvate, and acetate,
and also of the micronutrient selenite, whose structure
mimics that of monocarboxylates; expression and
localization are tightly regulated, with transcription
repression, mRNA degradation, and protein endocytosis and
degradation all occurring in the presence of glucose"
/codon_start=1
/product="monocarboxylate/H+ symporter"
/protein_id="DAA08952.1"
/db_xref="SGD:S000001700"
/translation="MSSSITDEKISGEQQQPAGRKLYYNTSTFAEPPLVDGEGNPINY
EPEVYNPDHEKLYHNPSLPAQSIQDTRDDELLERVYSQDQGVEYEEDEEDKPNLSAAS
IKSYALTRFTSLLHIHEFSWENVNPIPELRKMTWQNWNYFFMGYFAWLSAAWAFFCVS
VSVAPLAELYDRPTKDITWGLGLVLFVRSAGAVIFGLWTDKSSRKWPYITCLFLFVIA
QLCTPWCDTYEKFLGVRWITGIAMGGIYGCASATAIEDAPVKARSFLSGLFFSAYAMG
FIFAIIFYRAFGYFRDDGWKILFWFSIFLPILLIFWRLLWPETKYFTKVLKARKLILS
DAVKANGGEPLPKANFKQKMVSMKRTVQKYWLLFAYLVVLLVGPNYLTHASQDLLPTM
LRAQLGLSKDAVTVIVVVTNIGAICGGMIFGQFMEVTGRRLGLLIACTMGGCFTYPAF
MLRSEKAILGAGFMLYFCVFGVWGILPIHLAELAPADARALVAGLSYQLGNLASAAAS
TIETQLADRYPLERDASGAVIKEDYAKVMAILTGSVFIFTFACVFVGHEKFHRDLSSP
VMKKYINQVEEYEADGLSISDIVEQKTECASVKMIDSNVSKTYEEHIETV"
gene 25215..26159
/gene="URA1"
/locus_tag="YKL216W"
mRNA 25215..26159
/gene="URA1"
/locus_tag="YKL216W"
/product="dihydroorotate dehydrogenase"
CDS 25215..26159
/gene="URA1"
/locus_tag="YKL216W"
/EC_number="1.3.98.1"
/experiment="EXISTENCE:direct assay:GO:0004152
dihydroorotate dehydrogenase activity [PMID:1511880]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:1409592]"
/experiment="EXISTENCE:direct assay:GO:0006207 'de novo'
pyrimidine nucleobase biosynthetic process
[PMID:10871048]"
/experiment="EXISTENCE:mutant phenotype:GO:0004152
dihydroorotate dehydrogenase activity [PMID:4550660]"
/experiment="EXISTENCE:mutant phenotype:GO:0006207 'de
novo' pyrimidine nucleobase biosynthetic process
[PMID:5651325|PMID:4550660]"
/note="Dihydroorotate dehydrogenase; catalyzes the fourth
enzymatic step in the de novo biosynthesis of pyrimidines,
converting dihydroorotic acid into orotic acid"
/codon_start=1
/product="dihydroorotate dehydrogenase"
/protein_id="DAA08953.1"
/db_xref="SGD:S000001699"
/translation="MTASLTTKFLNNTYENPFMNASGVHCMTTQELDELANSKAGAFI
TKSATTLEREGNPEPRYISVPLGSINSMGLPNEGIDYYLSYVLNRQKNYPDAPAIFFS
VAGMSIDENLNLLRKIQDSEFNGITELNLSCPNVPGKPQVAYDFDLTKETLEKVFAFF
KKPLGVKLPPYFDFAHFDIMAKILNEFPLAYVNSINSIGNGLFIDVEKESVVVKPKNG
FGGIGGEYVKPTALANVRAFYTRLRPEIKVIGTGGIKSGKDAFEHLLCGASMLQIGTE
LQKEGVKIFERIEKELKDIMEAKGYTSIDQFRGKLNSI"
gene complement(26827..30687)
/gene="OXP1"
/locus_tag="YKL215C"
mRNA complement(26827..30687)
/gene="OXP1"
/locus_tag="YKL215C"
/product="5-oxoprolinase"
CDS complement(26827..30687)
/gene="OXP1"
/locus_tag="YKL215C"
/EC_number="3.5.2.9"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095|PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0017168
5-oxoprolinase (ATP-hydrolyzing) activity [PMID:20402795]"
/experiment="EXISTENCE:mutant phenotype:GO:0006749
glutathione metabolic process [PMID:20349993]"
/experiment="EXISTENCE:mutant phenotype:GO:0017168
5-oxoprolinase (ATP-hydrolyzing) activity [PMID:20402795]"
/note="5-oxoprolinase; enzyme is ATP-dependent and
functions as a dimer; similar to mouse Oplah gene; green
fluorescent protein (GFP)-fusion protein localizes to the
cytoplasm; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="5-oxoprolinase"
/protein_id="DAA08954.1"
/db_xref="SGD:S000001698"
/translation="MQKGNIRIAIDKGGTFTDCVGNIGTGKQEHDTVIKLLSVDPKNY
PDAPLEGIRRLLEVLEHKTIPRGIPLDISNVRSLRMGTTLATNCALERNGERCAFITT
KGFKDSLLIGDQTRPDIFNLNIKKVVPLYDTVVEIDERVTLEDFSEDPYFTKSSPNEQ
EGILEGNSGEMVRVIKKPDESSVRSILKVLYASGIKSIAIAFLHSYTFPDHERIVGNI
AREIGFSHVSLSSEVSPMIKFLPRAHSSVADAYLTPVIKKYLNSISAGLSHAEDTHIQ
FMQSDGGLVDGGKFSGLKSILSGPAGGVIGYSSTCYDKNNNIPLIGFDMGGTSTDVSR
YGDGRLEHVFETVTAGIIIQSPQLDIHTVAAGGSSILSWKNGLFRVGPDSAAADPGPA
AYRKGGPLTITDANLFLGRLVPEFFPKIFGPNEDESLDLETTTLKFRELTDVINKDLN
SNLTMEEVAYGFIKVANECMARPVRAITEAKGHVVSQHRLVSFGGAGGQHAIAVADSL
GIDTVLIHRYSSILSAYGIFLADVIEENQEPCSFILGEPETILKVKKRFLELSKNSIK
NLLSQSFSREDIVLERYLNLRYEGTETSLMILQKYDDQWNFREWFSEAHKKEFGFSFD
DKRIIIDDIRIRAIGKSGVRKEKTVDEQLIEISHFKKADVSKDASFTQKAYFDNKWVD
TAVFKIDDLPAGTIIEGPAILADGTQTNIILPNSQATILNSHIFIKINQKAAKTLSKS
GYELDIDPILLSIFSHRFMDIALQMGTQLRKTSVSTNVKERLDFSCALFDSKGNLVAN
APHVPVHLGSMSTCISAQAKLWEGKLKPGDVLITNHPDIGGTHLPDITVITPSFSSTG
ELIFYVASRAHHADIGGILPGSVPPNSKELYEEGTAIYSELVVKEGIFQEELIYKLFV
EDPGKYPGCSGSRRFSDNISDLKAQVAANTKGIQLIGSLTKEYDLATILKYMAAIQTN
ASESIKKMLAKMVEHFGTTKFSGEDRLDDGSLIKLQVIIRPEKEEYIFNFDGTSPQVY
GNLNAPEAITNSAILYCLRCLVGEDIPLNQGCLKPLTIKIPAGSLLSPRSGAAVVGGN
VLTSQRVTDVILKTFNVMADSQGDCNNFTFGTGGNSGNKTDKQIKGFGYYETICGGSG
AGADSWRGSGWNGSDAVHTNMTNTRMTDTEVFERRYPVLLKEFSIRRGSGGKGKYTGG
NGVVRDVQFRKAVTASILSERRVIGPHGIKGGQDGSRGENLWVRHSTGALINVGGKNT
IYAQPGDRFIIKTPGGGGFGQYKD"
gene complement(31082..31693)
/gene="YRA2"
/locus_tag="YKL214C"
mRNA complement(31082..31693)
/gene="YRA2"
/locus_tag="YKL214C"
/product="Yra2p"
CDS complement(31082..31693)
/gene="YRA2"
/locus_tag="YKL214C"
/experiment="EXISTENCE:direct assay:GO:0003723 RNA binding
[PMID:11390651]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:11390651]"
/experiment="EXISTENCE:mutant phenotype:GO:0016973
poly(A)+ mRNA export from nucleus [PMID:11390651]"
/note="Member of the REF (RNA and export factor binding
proteins) family; when overexpressed, can substitute for
the function of Yra1p in export of poly(A)+ mRNA from the
nucleus"
/codon_start=1
/product="Yra2p"
/protein_id="DAA08955.1"
/db_xref="SGD:S000001697"
/translation="MDKAFDEIIGNSHTDSSSNHKVTRYRRRDLRNELGPRLGFAPSD
AASRSKDRLYREREEPPLPKRIRISKIPLDVSDYTLDDMIKEFGSPIFSKIFDNKEDR
TCIYEFEDPEVLEKIVERYNGHELHNAKIEVEIYQPQRKHSRMNAHNRRKQTAQEHGR
GRPGSHYRQKPNRVSKKNKGREKNNTPTSVEALDAELDAYMKG"
gene complement(31960..34107)
/gene="DOA1"
/locus_tag="YKL213C"
/gene_synonym="UFD3"
/gene_synonym="ZZZ4"
mRNA complement(31960..34107)
/gene="DOA1"
/locus_tag="YKL213C"
/gene_synonym="UFD3"
/gene_synonym="ZZZ4"
/product="Doa1p"
CDS complement(31960..34107)
/gene="DOA1"
/locus_tag="YKL213C"
/gene_synonym="UFD3"
/gene_synonym="ZZZ4"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095|PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095|PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0036435 K48-linked
polyubiquitin modification-dependent protein binding
[PMID:28525741]"
/experiment="EXISTENCE:direct assay:GO:0043130 ubiquitin
binding [PMID:16428438|PMID:21070969]"
/experiment="EXISTENCE:genetic interaction:GO:0043161
proteasome-mediated ubiquitin-dependent protein catabolic
process [PMID:23525333]"
/experiment="EXISTENCE:mutant phenotype:GO:0006303
double-strand break repair via nonhomologous end joining
[PMID:12399380]"
/experiment="EXISTENCE:mutant phenotype:GO:0010992
ubiquitin recycling
[PMID:18508771|PMID:19805280|PMID:7615550]"
/experiment="EXISTENCE:mutant phenotype:GO:0034517
ribophagy [PMID:20508643]"
/experiment="EXISTENCE:mutant phenotype:GO:0043130
ubiquitin binding [PMID:16428438]"
/experiment="EXISTENCE:mutant phenotype:GO:0043161
proteasome-mediated ubiquitin-dependent protein catabolic
process [PMID:2111732|PMID:23525333]"
/experiment="EXISTENCE:mutant phenotype:GO:0072671
mitochondria-associated ubiquitin-dependent protein
catabolic process [PMID:32118579|PMID:21070972]"
/note="WD-repeat protein involved in Ub-mediated
proteolysis; K48-, K29-specific Ub chain binding protein
involved in Ub homeostasis; substrate-recruiting adaptor
for Cdc48p in mitochondria-associated degradation;
inhibits degradation of Ufd2p-dependent substrates;
facilitates proteolysis of Cse4p, a centromeric H3-like
protein; required for ribophagy; promotes NHEJ in
postdiauxic/stationary phase; protein increases in
abundance and relocalizes from nucleus to nuclear
periphery upon replication stress"
/codon_start=1
/product="Doa1p"
/protein_id="DAA08956.1"
/db_xref="SGD:S000001696"
/translation="MGYQLSATLKGHDQDVRDVVAVDDSKVASVSRDGTVRLWSKDDQ
WLGTVVYTGQGFLNSVCYDSEKELLLFGGKDTMINGVPLFATSGEDPLYTLIGHQGNV
CSLSFQDGVVISGSWDKTAKVWKEGSLVYNLQAHNASVWDAKVVSFSENKFLTASADK
TIKLWQNDKVIKTFSGIHNDVVRHLAVVDDGHFISCSNDGLIKLVDMHTGDVLRTYEG
HESFVYCIKLLPNGDIVSCGEDRTVRIWSKENGSLKQVITLPAISIWSVDCMSNGDII
VGSSDNLVRIFSQEKSRWASEDEINELSTQVEKSTISSKTIEFDESKLSPYEILQSPG
RKEGQIVVVKSPQGTIEAHQFSNSSWKKVGDVVGAGATGNDKKIEFEGKTYDYVFDVD
IEDGKPPLKLPINVSDNPYTAADNFLARYELPMSYRDQVVQFILKNTNGISLDQPNDN
ASSSAVSPSKTSVMKVLPVKQYLIMENYNPDTIFNGIVKINSNEKTFDDEILAQIGGA
LHDIDESWELLLSFANTIRSNWEIKTPAYDIVRLIVKKLPYSSDIKDYIEEGLGNKNI
TLTMLTVRILVNCFNNENWGVKLLESNQVYKSIFETIDTEFSQASAKQSQNLAIAVST
LIFNYSALVTKGNSDLELLPIVADAINTKYGPLEEYQECEEAAYRLTVAYGNLATVEP
TLRQFANSVTWLANIKRSYGNVPRFKDIFDDLS"
gene 34543..36414
/gene="SAC1"
/locus_tag="YKL212W"
/gene_synonym="RSD1"
mRNA 34543..36414
/gene="SAC1"
/locus_tag="YKL212W"
/gene_synonym="RSD1"
/product="phosphatidylinositol-3-phosphatase SAC1"
CDS 34543..36414
/gene="SAC1"
/locus_tag="YKL212W"
/gene_synonym="RSD1"
/EC_number="3.1.3.64"
/experiment="EXISTENCE:direct assay:GO:0000139 Golgi
membrane [PMID:15657391|PMID:8314848]"
/experiment="EXISTENCE:direct assay:GO:0004438
phosphatidylinositol-3-phosphate phosphatase activity
[PMID:10625610]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0005741
mitochondrial outer membrane [PMID:16407407]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005789 endoplasmic
reticulum membrane
[PMID:11514624|PMID:15657391|PMID:8314848]"
/experiment="EXISTENCE:direct assay:GO:0005797 Golgi
medial cisterna [PMID:22553352]"
/experiment="EXISTENCE:direct assay:GO:0032541 cortical
endoplasmic reticulum [PMID:30785834]"
/experiment="EXISTENCE:direct assay:GO:0035339 SPOTS
complex [PMID:20182505]"
/experiment="EXISTENCE:direct assay:GO:0043812
phosphatidylinositol-4-phosphate phosphatase activity
[PMID:10625610]"
/experiment="EXISTENCE:direct assay:GO:0046856
phosphatidylinositol dephosphorylation [PMID:10625610]"
/experiment="EXISTENCE:direct assay:GO:0052629
phosphatidylinositol-3,5-bisphosphate 3-phosphatase
activity [PMID:10625610]"
/experiment="EXISTENCE:genetic interaction:GO:0046856
phosphatidylinositol dephosphorylation [PMID:10625610]"
/experiment="EXISTENCE:mutant phenotype:GO:0000139 Golgi
membrane [PMID:15657391]"
/experiment="EXISTENCE:mutant phenotype:GO:0005789
endoplasmic reticulum membrane
[PMID:11514624|PMID:11792713|PMID:15657391]"
/experiment="EXISTENCE:mutant phenotype:GO:0046856
phosphatidylinositol dephosphorylation
[PMID:10625610|PMID:22553352]"
/experiment="EXISTENCE:mutant phenotype:GO:0061909
autophagosome-lysosome fusion [PMID:32693712]"
/experiment="EXISTENCE:mutant phenotype:GO:0072517 host
cell viral assembly compartment [PMID:32269127]"
/note="Phosphatidylinositol phosphate phosphatase; role in
early and medial Golgi PtdIns4P hydrolysis; regulated by
Vps74p interaction; ER localized transmembrane protein
which cycles through the Golgi; role in protein
trafficking, processing, secretion, and cell wall
maintenance; regulates sphingolipid biosynthesis by
modulating PtdIns(4)P metabolism; PtdIns4P PPase activity
is crucial for autophagosome-vacuole fusion during
autophagy; human homolog SACM1L complements autophagy
defects of the null"
/codon_start=1
/product="phosphatidylinositol-3-phosphatase SAC1"
/protein_id="DAA08957.1"
/db_xref="SGD:S000001695"
/translation="MTGPIVYVQNADGIFFKLAEGKGTNDAVIHLANQDQGVRVLGAE
EFPVQGEVVKIASLMGFIKLKLNRYAIIANTVEETGRFNGHVFYRVLQHSIVSTKFNS
RIDSEEAEYIKLLELHLKNSTFYFSYTYDLTNSLQRNEKVGPAASWKTADERFFWNHY
LTEDLRNFAHQDPRIDSFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFR
RGVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEINNLKYKPNLV
LGENSLDATKKHFDQQKELYGDNYLVNLVNQKGHELPVKEGYESVVHALNDPKIHYVY
FDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRTNC
MDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAPLLTSYQNLWADNADAVSV
AYSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGGFRPH
TASIKSPFPDRRPVYIQLIPMIICAALTVLGATIFFPKDRFTSSKNLLYFAGASIVLA
LSTKFMFKNGIQFVNWPKLVDVGFLVVHQTHDKEQQFKGLKYAQSPKFSKPDPLKRD"
gene complement(36699..38153)
/gene="TRP3"
/locus_tag="YKL211C"
mRNA complement(36699..38153)
/gene="TRP3"
/locus_tag="YKL211C"
/product="bifunctional anthranilate
synthase/indole-3-glycerol-phosphate synthase"
CDS complement(36699..38153)
/gene="TRP3"
/locus_tag="YKL211C"
/EC_number="4.1.1.48"
/EC_number="4.1.3.27"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:genetic interaction:GO:0004049
anthranilate synthase activity [PMID:3881257]"
/experiment="EXISTENCE:genetic interaction:GO:0004425
indole-3-glycerol-phosphate synthase activity
[PMID:6323449]"
/experiment="EXISTENCE:mutant phenotype:GO:0000162
tryptophan biosynthetic process [PMID:10790693]"
/experiment="EXISTENCE:mutant phenotype:GO:0004425
indole-3-glycerol-phosphate synthase activity
[PMID:3881257]"
/experiment="EXISTENCE:physical interaction:GO:0005950
anthranilate synthase complex [PMID:3881257]"
/note="Indole-3-glycerol-phosphate synthase; forms
bifunctional hetero-oligomeric anthranilate
synthase:indole-3-glycerol phosphate synthase enzyme
complex with Trp2p"
/codon_start=1
/product="bifunctional anthranilate
synthase/indole-3-glycerol-phosphate synthase"
/protein_id="DAA08958.1"
/db_xref="SGD:S000001694"
/translation="MSVHAATNPINKHVVLIDNYDSFTWNVYEYLCQEGAKVSVYRND
AITVPEIAALNPDTLLISPGPGHPKTDSGISRDCIRYFTGKIPVFGICMGQQCMFDVF
GGEVAYAGEIVHGKTSPISHDNCGIFKNVPQGIAVTRYHSLAGTESSLPSCLKVTAST
ENGIIMGVRHKKYTVEGVQFHPESILTEEGHLMIRNILNVSGGTWEENKSSPSNSILD
RIYARRKIDVNEQSKIPGFTFQDLQSNYDLGLAPPLQDFYTVLSSSHKRAVVLAEVKR
ASPSKGPICLKAVAAEQALKYAEAGASAISVLTEPHWFHGSLQDLVNVRKILDLKFPP
KERPCVLRKEFIFSKYQILEARLAGADTVLLIVKMLSQPLLKELYSYSKDLNMEPLVE
VNSKEELQRALEIGAKVVGVNNRDLHSFNVDLNTTSNLVESIPKDVLLIALSGITTRD
DAEKYKKEGVHGFLVGEALMKSTDVKKFIHELCE"
gene 38811..38911
/gene="SNR64"
/locus_tag="YNCK0001W"
ncRNA 38811..38911
/ncRNA_class="snoRNA"
/gene="SNR64"
/locus_tag="YNCK0001W"
/product="SNR64"
/experiment="EXISTENCE:curator inference:GO:0005730
nucleolus [PMID:10024243]"
/experiment="EXISTENCE:curator inference:GO:0031428 box
C/D RNP complex [PMID:10024243]"
/experiment="EXISTENCE:mutant phenotype:GO:0030562 rRNA
2'-O-ribose methylation guide activity [PMID:10024243]"
/experiment="EXISTENCE:mutant phenotype:GO:0031167 rRNA
methylation [PMID:10024243]"
/note="C/D box small nucleolar RNA (snoRNA); guides
2'-O-methylation of large subunit (LSU) rRNA at position
C2337"
/db_xref="SGD:S000006455"
gene 39163..42237
/gene="UBA1"
/locus_tag="YKL210W"
mRNA 39163..42237
/gene="UBA1"
/locus_tag="YKL210W"
/product="E1 ubiquitin-activating protein UBA1"
CDS 39163..42237
/gene="UBA1"
/locus_tag="YKL210W"
/EC_number="6.2.1.45"
/experiment="EXISTENCE:direct assay:GO:0004839 ubiquitin
activating enzyme activity [PMID:1989885]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:22842922|PMID:7629121]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:22842922|PMID:7629121]"
/experiment="EXISTENCE:direct assay:GO:0016567 protein
ubiquitination [PMID:1989885]"
/note="Ubiquitin activating enzyme (E1); involved in
ubiquitin-mediated protein degradation and essential for
viability; protein abundance increases in response to DNA
replication stress"
/codon_start=1
/product="E1 ubiquitin-activating protein UBA1"
/protein_id="DAA08959.1"
/db_xref="SGD:S000001693"
/translation="MSSNNSGLSAAGEIDESLYSRQLYVLGKEAMLKMQTSNVLILGL
KGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAEL
NAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLF
GNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEG
LDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNP
EFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQP
EVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFD
SLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEML
KNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPD
LKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLES
GTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYF
TDSAENVNMYLTQPNFVEQTLKQSGDVKGVLESISDSLSSKPHNFEDCIKWARLEFEK
KFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAY
NYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPNANAANGSDEI
DQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTK
FIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIAS
PKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPK
KLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL"
gene complement(42423..46295)
/gene="STE6"
/locus_tag="YKL209C"
mRNA complement(42423..46295)
/gene="STE6"
/locus_tag="YKL209C"
/product="ATP-binding cassette a-factor transporter STE6"
CDS complement(42423..46295)
/gene="STE6"
/locus_tag="YKL209C"
/EC_number="7.4.2.7"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:8045256]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:7679674]"
/experiment="EXISTENCE:direct assay:GO:0015440 ABC-type
peptide transporter activity [PMID:8626301|PMID:11389139]"
/experiment="EXISTENCE:direct assay:GO:0043332 mating
projection tip [PMID:12374868|PMID:7679674]"
/experiment="EXISTENCE:mutant phenotype:GO:0000770 peptide
pheromone export [PMID:2569166]"
/experiment="EXISTENCE:mutant phenotype:GO:0015440
ABC-type peptide transporter activity
[PMID:8626301|PMID:11389139]"
/note="Plasma membrane ATP-binding cassette (ABC)
transporter; required for the export of a-factor,
catalyzes ATP hydrolysis coupled to a-factor transport;
contains 12 transmembrane domains and two ATP binding
domains; expressed only in MATa cells; human homolog ABCB1
mediates multidrug resistance in many
chemotherapy-resistant tumors by effluxing toxic compounds
from the cell"
/codon_start=1
/product="ATP-binding cassette a-factor transporter STE6"
/protein_id="DAA08960.1"
/db_xref="SGD:S000001692"
/translation="MNFLSFKTTKHYHIFRYVNIRNDYRLLMIMIIGTVATGLVPAIT
SILTGRVFDLLSVFVANGSHQGLYSQLVQRSMAVMALGAASVPVMWLSLTSWMHIGER
QGFRIRSQILEAYLEEKPMEWYDNNEKLLGDFTQINRCVEELRSSSAEASAITFQNLV
AICALLGTSFYYSWSLTLIILCSSPIITFFAVVFSRMIHVYSEKENSETSKAAQLLTW
SMNAAQLVRLYCTQRLERKKFKEIILNCNTFFIKSCFFVAANAGILRFLTLTMFVQGF
WFGSAMIKKGKLNINDVITCFHSCIMLGSTLNNTLHQIVVLQKGGVAMEKIMTLLKDG
SKRNPLNKTVAHQFPLDYATSDLTFANVSFSYPSRPSEAVLKNVSLNFSAGQFTFIVG
KSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLR
KNILLGSTDSVRNADCSTNENRHLIKDACQMALLDRFILDLPDGLETLIGTGGVTLSG
GQQQRVAIARAFIRDTPILFLDEAVSALDIVHRNLLMKAIRHWRKGKTTIILTHELSQ
IESDDYLYLMKEGEVVESGTQSELLADPTTTFSTWYHLQNDYSDAKTIVDTETEEKSI
HTVESFNSQLETPKLGSCLSNLGYDETDQLSFYEAIYQKRSNVRTRRVKVEEENIGYA
LKQQKNTESSTGPQLLSIIQIIKRMIKSIRYKKILILGLLCSLIAGATNPVFSYTFSF
LLEGIVPSTDGKTGSSHYLAKWSLLVLGVAAADGIFNFAKGFLLDCCSEYWVMDLRNE
VMEKLTRKNMDWFSGENNKASEISALVLNDLRDLRSLVSEFLSAMTSFVTVSTIGLIW
ALVSGWKLSLVCISMFPLIIIFSAIYGGILQKCETDYKTSVAQLENCLYQIVTNIKTI
KCLQAEFHFQLTYHDLKIKMQQIASKRAIATGFGISMTNMIVMCIQAIIYYYGLKLVM
IHEYTSKEMFTTFTLLLFTIMSCTSLVSQIPDISRGQRAASWIYRILDEKHNTLEVEN
NNARTVGIAGHTYHGKEKKPIVSIQNLTFAYPSAPTAFVYKNMNFDMFCGQTLGIIGE
SGTGKSTLVLLLTKLYNCEVGKIKIDGTDVNDWNLTSLRKEISVVEQKPLLFNGTIRD
NLTYGLQDEILEIEMYDALKYVGIHDFVISSPQGLDTRIDTTLLSGGQAQRLCIARAL
LRKSKILILDECTSALDSVSSSIINEIVKKGPPALLTMVITHSEQMMRSCNSIAVLKD
GKVVERGNFDTLYNNRGELFQIVSNQSS"
gene complement(46735..46806)
/gene="TRT2"
/locus_tag="YNCK0002C"
tRNA complement(46735..46806)
/gene="TRT2"
/locus_tag="YNCK0002C"
/product="tRNA-Thr"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
analysis; correct folding and efficient aminoacylation
require Lhp1p"
/db_xref="SGD:S000006748"
gene 47157..47972
/gene="CBT1"
/locus_tag="YKL208W"
/gene_synonym="SOC1"
mRNA 47157..47972
/gene="CBT1"
/locus_tag="YKL208W"
/gene_synonym="SOC1"
/product="Cbt1p"
CDS 47157..47972
/gene="CBT1"
/locus_tag="YKL208W"
/gene_synonym="SOC1"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0006397 mRNA
processing [PMID:9339340]"
/experiment="EXISTENCE:direct assay:GO:0017004 cytochrome
complex assembly [PMID:9339340]"
/experiment="EXISTENCE:mutant phenotype:GO:0006397 mRNA
processing [PMID:16118200|PMID:9339340]"
/experiment="EXISTENCE:mutant phenotype:GO:0017004
cytochrome complex assembly [PMID:9339340]"
/experiment="EXISTENCE:mutant phenotype:GO:0048255 mRNA
stabilization [PMID:16118200]"
/note="Protein involved in 5' RNA end processing;
substrates include mitochondrial COB, 15S_rRNA, and RPM1
transcripts; may also have a role in 3' end processing of
the COB pre-mRNA; displays genetic interaction with cell
cycle-regulated kinase Dbf2p"
/codon_start=1
/product="Cbt1p"
/protein_id="DAA08961.1"
/db_xref="SGD:S000001691"
/translation="MVSYGSHSSEVSKVLKTPKFVLRYGNVSSKQRFALKRKINYKLR
ESKYQEYLNEYNTFVLYDWENSGAGSLVDSSYNLPSLWKEFITEGISKGAINDKLPTV
FMKRKLTNSALGHCLGLDFLTDPSESEHEYRCMFQTVQDIPSLSQLILFNSMPNVPVR
LKLHTIGININFGCKRSLISNGGDQDTEMSEAVSYIQPLLEESSRMYRNLNYWKLLKI
ARNNKKDEPLDQSTRIKSQVKLLLSQLATNRITSPSVTDHGGHNWLIFTRRRL"
gene 48194..48955
/gene="EMC3"
/locus_tag="YKL207W"
/gene_synonym="AIM27"
mRNA 48194..48955
/gene="EMC3"
/locus_tag="YKL207W"
/gene_synonym="AIM27"
/product="Emc3p"
CDS 48194..48955
/gene="EMC3"
/locus_tag="YKL207W"
/gene_synonym="AIM27"
/experiment="EXISTENCE:direct assay:GO:0072546 EMC complex
[PMID:19325107]"
/experiment="EXISTENCE:genetic interaction:GO:0034975
protein folding in endoplasmic reticulum [PMID:19325107]"
/note="Member of conserved ER transmembrane complex;
required for efficient folding of proteins in the ER;
required for respiratory growth; null mutant displays
induction of the unfolded protein response; homologous to
worm Y62E10A.10/EMC-3, fly CG6750, human TMEM111"
/codon_start=1
/product="Emc3p"
/protein_id="DAA08962.1"
/db_xref="SGD:S000001690"
/translation="MLLDDQLKYWVLLPISIVMVLTGVLKQYIMTLITGSSANEAQPR
VKLTEWQYLQWAQLLIGNGGNLSSDAFAAKKEFLVKDLTEERHLAKAKQQDGSQAGEV
PNPFNDPSMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAKFKEML
QTGIICQDLDVRWVSSISWYFISVLGLNPVYNLIGLNDQDMGIQAGIGGPQGPQGPPQ
SQVDKAMHAMANDLTIIQHETCLDNVEQRVLKQYM"
gene complement(49006..49809)
/gene="ADD66"
/locus_tag="YKL206C"
/gene_synonym="PBA2"
/gene_synonym="POC2"
mRNA complement(49006..49809)
/gene="ADD66"
/locus_tag="YKL206C"
/gene_synonym="PBA2"
/gene_synonym="POC2"
/product="Add66p"
CDS complement(49006..49809)
/gene="ADD66"
/locus_tag="YKL206C"
/gene_synonym="PBA2"
/gene_synonym="POC2"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:17634286]"
/experiment="EXISTENCE:genetic interaction:GO:0043248
proteasome assembly [PMID:17431397]"
/experiment="EXISTENCE:mutant phenotype:GO:0043248
proteasome assembly [PMID:17634286]"
/note="Protein involved in 20S proteasome assembly; forms
a heterodimer with Pba1p that binds to proteasome
precursors; interaction with Pba1p-Add66p may affect
function of the mature proteasome and its role in
maintaining respiratory metabolism; similar to human PAC2
constituent of the PAC1-PAC2 complex involved in
proteasome assembly"
/codon_start=1
/product="Add66p"
/protein_id="DAA08963.1"
/db_xref="SGD:S000001689"
/translation="MSCLVLPLVSVGNIPQLSIDWLLNSQANEWEYLEALDSKYLVEF
VGPLDRPEDGSDSLYKDADMKYSSALEVFYNKKRGLFAIQQRTPLVSVNYLNNFIVEI
ILPFLSKYNISEICIWDSLYAMEDENGVIVRPQEVYSLGEFYFDDEAELLSNLHLNDQ
ESMVNNWLHFTPTSFQDKISVDQPIFKILFQILNASQRPKALRSIKYCSCLANEGDNS
LDSQQFLQWIISQKVIKNAPPIVKFVRPISWQGAYGMADARDKFVDLYN"
gene 50051..53353
/gene="LOS1"
/locus_tag="YKL205W"
mRNA 50051..53353
/gene="LOS1"
/locus_tag="YKL205W"
/product="Ran GTPase-binding protein LOS1"
CDS 50051..53353
/gene="LOS1"
/locus_tag="YKL205W"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:18045534]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0016363 nuclear
matrix [PMID:8366091]"
/experiment="EXISTENCE:direct assay:GO:0031267 small
GTPase binding [PMID:9774653]"
/experiment="EXISTENCE:genetic interaction:GO:0071528 tRNA
re-export from nucleus [PMID:20032305]"
/experiment="EXISTENCE:mutant phenotype:GO:0006409 tRNA
export from nucleus [PMID:9802895]"
/note="Nuclear pore protein; involved in nuclear export of
pre-tRNA and in re-export of mature tRNAs after their
retrograde import from the cytoplasm; deletion mutation
extends replicative lifespan, as does exclusion of Los1p
from the nucleus in response to caloric restriction"
/codon_start=1
/product="Ran GTPase-binding protein LOS1"
/protein_id="DAA08964.1"
/db_xref="SGD:S000001688"
/translation="MLERIQQLVNAVNDPRSDVATKRQAIELLNGIKSSENALEIFIS
LVINENSNDLLKFYGLSTLIELMTEGVNANPNGLNLVKFEITKWLKFQVLGNKQTKLP
DFLMNKISEVLTTLFMLMYSDCNGNQWNSFFDDLMSLFQVDSAISNTSPSTDGNILLG
LEFFNKLCLMINSEIADQSFIRSKESQLKNNNIKDWMRDNDIMKLSNVWFQCLKLDEQ
IVSQCPGLINSTLDCIGSFISWIDINLIIDANNYYLQLIYKFLNLKETKISCYNCILA
IISKKMKPMDKLAFLNMINLTNELTYYHQAISMNPQIITFDNLEVWESLTKLITSFGI
EFTIIIEQVNDDQKLDTLYKQSVISNVDSILLEKIIPILLEFMNNEFDSITAKTFPFW
SNYLAFLKKYKASSPNFVPLHKDFLDNFQQICFKRMKFSDDEVTQDDFEEFNETVRFK
LKNFQEIIVVIDPSLFLNNISQEISANLMNCKNESWQIFELTIYQIFNLSECTKNNYF
GLNKNEIMTSQPSLTLVRFLNELLMMKDFLLAIDNEQIQILFMELIVKNYNFIFSTSA
NTANATDDDEKYLLILNIFMSSFAMFNKRENVRLRSWYLFTRFLKLTRINLKKILFAN
KNLVNEITNKISPLLHIKVTSINAQGTDDNDTIFDNQLYIFEGIGFIITLNNSSQELT
AATANTPIDYDILDQILTPLFTQLEGCITQGASPVVILECHHILMAIGTLARGLHIGL
VPENQVNNMVVNKKLINDSLIHKFSNIAEVILVTFSFFNKFENIRDASRFTFARLIPI
LSNKILPFINKLIELILSSTDLKSWEMIDFLGFLSQLIHMFHTDTDCYQLFNQLLTPL
INKVHSIIEEIDEQHDQQSSSNKPIDTAVTATSVNKNIVVTDSYRDKILLKKAYCTFL
QSFTNNSVTSILLSDINRAILPVILNDLVTYTPQEIQETSMMKVSLNVLCNFIKCFGN
GTCLDNDDINKDPNLKIDGLNEYFIMKCVPIIFEIPFNPIYKFNIKEGNFKTMAYDLA
RLLRELFIVSSNPTTNENECVKYLTQIYLPQIQLPQELTIQLVNMLTTMGQKQFEKWF
VDNFISVLKQGQ"
gene 53704..55602
/gene="EAP1"
/locus_tag="YKL204W"
mRNA 53704..55602
/gene="EAP1"
/locus_tag="YKL204W"
/product="Eap1p"
CDS 53704..55602
/gene="EAP1"
/locus_tag="YKL204W"
/experiment="EXISTENCE:direct assay:GO:0003729 mRNA
binding [PMID:23222640]"
/experiment="EXISTENCE:direct assay:GO:0008190 eukaryotic
initiation factor 4E binding [PMID:10848587]"
/experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
stress granule [PMID:18981231|PMID:26777405]"
/experiment="EXISTENCE:direct assay:GO:0017148 negative
regulation of translation [PMID:10848587]"
/experiment="EXISTENCE:mutant phenotype:GO:0000290
deadenylation-dependent decapping of nuclear-transcribed
mRNA [PMID:22890846]"
/experiment="EXISTENCE:mutant phenotype:GO:0006402 mRNA
catabolic process [PMID:22890846]"
/experiment="EXISTENCE:mutant phenotype:GO:0017148
negative regulation of translation [PMID:10848587]"
/note="eIF4E-associated protein, competes with eIF4G for
binding to eIF4E; accelerates mRNA degradation by
promoting decapping, facilitated by interaction with
eIF4E; essential for Puf5p mediated repression; associates
with Puf5p and Dhh1p; inhibits cap-dependent translation;
functions independently of eIF4E to maintain genetic
stability; plays a role in cell growth, implicated in the
TOR signaling cascade"
/codon_start=1
/product="Eap1p"
/protein_id="DAA08965.1"
/db_xref="SGD:S000001687"
/translation="MELNDPSIISSSQFSGELSDSDTAAATHKSQQAISNLFQKLAKK
GREEKPIGSVESSTDSSNISVATSGNNKESNKKKNKKTAMLNFSSLTDPITNYKPMDL
QYKTYAYSMNELYHLKPSLASASYEEDPLISELVRSLPKRKFWRLRMGPPDQKHANNH
HFNGNNGGGSWKAGYKNGKNDERRMSRTKNMQGGKRRSQQDDEEKKIDQEMLEMDKNL
QLGGDVGHSIADFEDWKAKMKELELKKLSKSKGISNSTAIAPRESASHETPTDLRPVI
PRGPSSITDFLNLKRQDKKEESSQQTPGIPVGQPSLSKTSIEQVNELETNSDLGKSSS
SRFSSFFNKSATSLPSLDNNNQVPSSNVSVVNNDGNSTPHQSGSRLMSFFKESRSSTP
NAESQLLSASDKDNGKMQTLPQFQQQPQQMQPMAFTQHPPNNNAFFNGLLNKGKSETS
TPPPPPPGLIAHQGPQFPVMGVPPNFPQRMMPPPPGLVQFQKDSKDVNKKEDRQLRQN
KNPNGTRNSKGKQEETATPDLPQQQYMPPPPPPGFFPMHPNFPNGPMPPLPQGFPIPP
NGMLPVTGQQPQPPYPNMMLQGNFPPNFQQGFGSNSPMPIPSIINANGKNVTNQLPPG
LNSKKNIK"
rep_origin 55671..55917
/note="ARS1103; Autonomously Replicating Sequence"
/db_xref="SGD:S000118401"
gene complement(55935..63359)
/gene="TOR2"
/locus_tag="YKL203C"
/gene_synonym="DRR2"
mRNA complement(55935..63359)
/gene="TOR2"
/locus_tag="YKL203C"
/gene_synonym="DRR2"
/product="phosphatidylinositol kinase-related protein
kinase TOR2"
CDS complement(55935..63359)
/gene="TOR2"
/locus_tag="YKL203C"
/gene_synonym="DRR2"
/EC_number="2.7.1.67"
/EC_number="2.7.11.1"
/experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
vacuole membrane [PMID:8846782]"
/experiment="EXISTENCE:direct assay:GO:0004674 protein
serine/threonine kinase activity
[PMID:16055732|PMID:22307609]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:10973982]"
/experiment="EXISTENCE:genetic interaction:GO:0010507
negative regulation of autophagy [PMID:9461583]"
/experiment="EXISTENCE:genetic interaction:GO:0035025
positive regulation of Rho protein signal transduction
[PMID:9038344]"
/experiment="EXISTENCE:mutant phenotype:GO:0004674 protein
serine/threonine kinase activity [PMID:16055732]"
/experiment="EXISTENCE:mutant phenotype:GO:0007010
cytoskeleton organization [PMID:9475724]"
/experiment="EXISTENCE:mutant phenotype:GO:0030950
establishment or maintenance of actin cytoskeleton
polarity [PMID:12408816]"
/experiment="EXISTENCE:mutant phenotype:GO:0031929 TOR
signaling [PMID:12719473|PMID:8186460]"
/experiment="EXISTENCE:mutant phenotype:GO:0035025
positive regulation of Rho protein signal transduction
[PMID:9038344]"
/experiment="EXISTENCE:mutant phenotype:GO:0042254
ribosome biogenesis [PMID:10198052]"
/experiment="EXISTENCE:mutant phenotype:GO:0045807
positive regulation of endocytosis [PMID:14593073]"
/experiment="EXISTENCE:mutant phenotype:GO:1905356
regulation of snRNA pseudouridine synthesis
[PMID:27268497]"
/experiment="EXISTENCE:physical interaction:GO:0005515
protein binding [PMID:12631735]"
/experiment="EXISTENCE:physical interaction:GO:0031931
TORC1 complex [PMID:12408816]"
/experiment="EXISTENCE:physical interaction:GO:0031932
TORC2 complex [PMID:12408816]"
/note="PIK-related protein kinase and rapamycin target;
subunit of TORC1, a complex that regulates growth in
response to nutrients and TORC2, a complex that regulates
plasma membrane (PM) homeostasis and cell-cycle dependent
polarization of the actin cytoskeleton; involved in
meiosis; PM retention is dependent on Avo3p; malonyl-CoA
is a direct ATP-competitive inhibitor of TORC1; TOR2 has a
paralog, TOR1, that arose from the whole genome
duplication"
/codon_start=1
/product="phosphatidylinositol kinase-related protein
kinase TOR2"
/protein_id="DAA08966.1"
/db_xref="SGD:S000001686"
/translation="MNKYINKYTTPPNLLSLRQRAEGKHRTRKKLTHKSHSHDDEMST
TSNTDSNHNGPNDSGRVITGSAGHIGKISFVDSELDTTFSTLNLIFDKLKSDVPQERA
SGANELSTTLTSLAREVSAEQFQRFSNSLNNKIFELIHGFTSSEKIGGILAVDTLISF
YLSTEELPNQTSRLANYLRVLIPSSDIEVMRLAANTLGRLTVPGGTLTSDFVEFEVRT
CIDWLTLTADNNSSSSKLEYRRHAALLIIKALADNSPYLLYPYVNSILDNIWVPLRDA
KLIIRLDAAVALGKCLTIIQDRDPALGKQWFQRLFQGCTHGLSLNTNDSVHATLLVFR
ELLSLKAPYLRDKYDDIYKSTMKYKEYKFDVIRREVYAILPLLAAFDPAIFTKKYLDR
IMVHYLRYLKNIDMNAANNSDKPFILVSIGDIAFEVGSSISPYMTLILDNIREGLRTK
FKVRKQFEKDLFYCIGKLACALGPAFAKHLNKDLLNLMLNCPMSDHMQETLMILNEKI
PSLESTVNSRILNLLSISLSGEKFIQSNQYDFNNQFSIEKARKSRNQSFMKKTGESND
DITDAQILIQCFKMLQLIHHQYSLTEFVRLITISYIEHEDSSVRKLAALTSCDLFIKD
DICKQTSVHALHSVSEVLSKLLMIAITDPVAEIRLEILQHLGSNFDPQLAQPDNLRLL
FMALNDEIFGIQLEAIKIIGRLSSVNPAYVVPSLRKTLLELLTQLKFSNMPKKKEESA
TLLCTLINSSDEVAKPYIDPILDVILPKCQDASSAVASTALKVLGELSVVGGKEMTRY
LKELMPLIINTFQDQSNSFKRDAALTTLGQLAASSGYVVGPLLDYPELLGILINILKT
ENNPHIRRGTVRLIGILGALDPYKHREIEVTSNSKSSVEQNAPSIDIALLMQGVSPSN
DEYYPTVVIHNLMKILNDPSLSIHHTAAIQAIMHIFQNLGLRCVSFLDQIIPGIILVM
RSCPPSQLDFYFQQLGSLISIVKQHIRPHVEKIYGVIREFFPIIKLQITIISVIESIS
KALEGEFKRFVPETLTFFLDILENDQSNKRIVPIRILKSLVTFGPNLEDYSHLIMPIV
VRMTEYSAGSLKKISIITLGRLAKNINLSEMSSRIVQALVRILNNGDRELTKATMNTL
SLLLLQLGTDFVVFVPVINKALLRNRIQHSVYDQLVNKLLNNECLPTNIIFDKENEVP
ERKNYEDEMQVTKLPVNQNILKNAWYCSQQKTKEDWQEWIRRLSIQLLKESPSACLRS
CSSLVSVYYPLARELFNASFSSCWVELQTSYQEDLIQALCKALSSSENPPEIYQMLLN
LVEFMEHDDKPLPIPIHTLGKYAQKCHAFAKALHYKEVEFLEEPKNSTIEALISINNQ
LHQTDSAIGILKHAQQHNELQLKETWYEKLQRWEDALAAYNEKEAAGEDSVEVMMGKL
RSLYALGEWEELSKLASEKWGTAKPEVKKAMAPLAAGAAWGLEQWDEIAQYTSVMKSQ
SPDKEFYDAILCLHRNNFKKAEVHIFNARDLLVTELSALVNESYNRAYNVVVRAQIIA
ELEEIIKYKKLPQNSDKRLTMRETWNTRLLGCQKNIDVWQRILRVRSLVIKPKEDAQV
RIKFANLCRKSGRMALAKKVLNTLLEETDDPDHPNTAKASPPVVYAQLKYLWATGLQD
EALKQLINFTSRMAHDLGLDPNNMIAQSVPQQSKRVPRHVEDYTKLLARCFLKQGEWR
VCLQPKWRLSNPDSILGSYLLATHFDNTWYKAWHNWALANFEVISMLTSVSKKKQEGS
DASSVTDINEFDNGMIGVNTFDAKEVHYSSNLIHRHVIPAIKGFFHSISLSESSSLQD
ALRLLTLWFTFGGIPEATQAMHEGFNLIQIGTWLEVLPQLISRIHQPNQIVSRSLLSL
LSDLGKAHPQALVYPLMVAIKSESLSRQKAALSIIEKMRIHSPVLVDQAELVSHELIR
MAVLWHEQWYEGLDDASRQFFGEHNTEKMFAALEPLYEMLKRGPETLREISFQNSFGR
DLNDAYEWLMNYKKSKDVSNLNQAWDIYYNVFRKIGKQLPQLQTLELQHVSPKLLSAH
DLELAVPGTRASGGKPIVKISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHED
IRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVL
IREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKS
RSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAA
ILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAF
DPLINWGFDLPTKKIEEETGIQLPVMNANELLSNGAITEEEVQRVENEHKNAIRNARA
MLVLKRITDKLTGNDIRRFNDLDVPEQVDKLIQQATSVENLCQHYIGWCPFW"
gene complement(63930..67466)
/gene="MNN4"
/locus_tag="YKL201C"
/gene_synonym="YKL200C"
mRNA complement(63930..67466)
/gene="MNN4"
/locus_tag="YKL201C"
/gene_synonym="YKL200C"
/product="Mnn4p"
CDS complement(63930..67466)
/gene="MNN4"
/locus_tag="YKL201C"
/gene_synonym="YKL200C"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:30842360]"
/experiment="EXISTENCE:mutant phenotype:GO:0006487 protein
N-linked glycosylation [PMID:9023541]"
/experiment="EXISTENCE:mutant phenotype:GO:0006493 protein
O-linked glycosylation [PMID:9813355]"
/experiment="EXISTENCE:mutant phenotype:GO:0008047 enzyme
activator activity [PMID:9459307]"
/note="Putative positive regulator of mannosylphosphate
transferase Mnn6p; involved in mannosylphosphorylation of
N-linked oligosaccharides; may also function as a
mannosylphosphate transferase; expression increases in
late-logarithmic and stationary growth phases; coding
sequence contains length polymorphisms in different
strains; MNN4 has a paralog, YJR061W, that arose from the
whole genome duplication"
/codon_start=1
/product="Mnn4p"
/protein_id="DAA08967.1"
/db_xref="SGD:S000001684"
/translation="MLQRISSKLHRRFLSGLLRVKHYPLRRILLPLILLQIIIITFIW
SNSPQRNGLGRDADYLLPNYNELDSDDDSWYSILTSSFKNDRKIQFAKTLYENLKFGT
NPKWVNEYTLQNDLLSVKMGPRKGSKLESVDELKFYDFDPRLTWSVVLNHLQNNDADQ
PEKLPFSWYDWTTFHELNKLISIDKTVLPCNFLFQSAFDKESLEAIETELGEPLFLYE
RPKYAQKLWYKAARNQDRIKDSKELKKHCSKLFTPDGHGSPKGLRFNTQFQIKELYDK
VRPEVYQLQARNYILTTQSHPLSISIIESDNSTYQVPLQTEKSKNLVQSGLLQEYIND
NINSTNKRKKNKQDVEFNHNRLFQEFVNNDQVNSLYKLEIEETDKFTFDKDLVYLSPS
DFKFDASKKIEELEEQKKLYPDKFSAHNENYLNSLKNSVKTSPALQRKFFYEAGAVKQ
YKGMGFHRDKRFFNVDTLINDKQEYQARLNSMIRTFQKFTKANGIISWLSHGTLYGYL
YNGMAFPWDNDFDLQMPIKHLQLLSQYFNQSLILEDPRQGNGRYFLDVSDSLTVRING
NGKNNIDARFIDVDTGLYIDITGLASTSAPSRDYLNSYIEERLQEEHLDINNIPESNG
ETATLPDKVDDGLVNMATLNITELRDYITSDENKNHKRVPTDTDLKDLLKKELEELPK
SKTIENKLNPKQRYFLNEKLKLYNCRNNHFNSFEELSPLINTVFHGVPALIPHRHTYC
LHNEYHVPDRYAFDAYKNTAYLPEFRFWFDYDGLKKCSNINSWYPNIPSINSWNPNLL
KEISSTKFESKLFDSNKVSEYSFKNLSMDDVRLIYKNIPKAGFIEVFTNLYNSFNVTA
YRQKELEIQYCQNLTFIEKKKLLHQLRINVAPKLSSPAKDPFLFGYEKAMWKDLSKSM
NQTTLDQVTKIVHEEYVGKIIDLSESLKYRNFSLFNITFDETGTTLDDNTEDYTPANT
VEVNPVDFKSNLNFSSNSFLDLNSYGLDLFAPTLSDVNRKGIQMFDKDPIIVYEDYAY
AKLLEERKRREKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEE
EKKKQEEEEKKKKEEEEKKKQEEGEKMKNEDEENKKNEDEEKKKNEEEEKKKQEEKNK
KNEDEEKKKQEEEEKKKNEEEEKKKQEEGHSN"
gene complement(68232..70220)
/gene="PTK1"
/locus_tag="YKL198C"
/gene_synonym="KKT8"
/gene_synonym="POT1"
/gene_synonym="STK1"
/gene_synonym="YKL199C"
/gene_synonym="YKT9"
mRNA complement(68232..70220)
/gene="PTK1"
/locus_tag="YKL198C"
/gene_synonym="KKT8"
/gene_synonym="POT1"
/gene_synonym="STK1"
/gene_synonym="YKL199C"
/gene_synonym="YKT9"
/product="putative serine/threonine protein kinase PTK1"
CDS complement(68232..70220)
/gene="PTK1"
/locus_tag="YKL198C"
/gene_synonym="KKT8"
/gene_synonym="POT1"
/gene_synonym="STK1"
/gene_synonym="YKL199C"
/gene_synonym="YKT9"
/EC_number="2.7.11.1"
/experiment="EXISTENCE:genetic interaction:GO:0000296
spermine transport [PMID:7488221]"
/note="Putative serine/threonine protein kinase; regulates
spermine uptake; involved in polyamine transport; possible
mitochondrial protein; PTK1 has a paralog, PTK2, that
arose from the whole genome duplication"
/codon_start=1
/product="putative serine/threonine protein kinase PTK1"
/protein_id="DAA08968.2"
/db_xref="SGD:S000001681"
/translation="MTVSHNHSTKISQQPISSVSAFKFFGKKLLSSSHGNKLKKKASL
PPDFHSTSTNDSESSSPKLPNSLKTSRRANSFAHTTNSKRSLSSASTKILPPAGSSTS
ISRGNRHSSTSRNLSNSKFSSERLVYNPYGVSTPSTSLSSVSTSMKKDPDLGFYLHDG
DSKIRMLPIPIVDPNEYLPDEMKEASIQLSDNFVFDDENKTIGWGGSCEVRKIRSKYR
KKDVFALKKLNMIYNETPEKFYKRCSKEFIIAKQLSHHVHITNTFLLVKVPTTVYTTR
GWGFVMELGLRDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPEN
VLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYD
TELQQPYDPRALDCYGLGIILMTLVNNVIPFLESCSFDTGFRDYCDAYENFIRLHDRA
FRNRGNYRPGPGMEYHLARNFKNGHASRVAWRLADPEAATRYTIDDLFEDPWFQGIET
CVDANDKYVCKKPIIKTTTYENPRGFHIATDVAATTPTSNPFLKNRVPIRSMVDIAAH
PSPTATVLASSPPPPPPATHVPAEALFTLRETPPPQLATLTLSEEPPATPAPSAPSAP
SARVRGHSPHRVVHHHLNIVNSLVHSSSAASSQVPAST"
gene complement(70734..73865)
/gene="PEX1"
/locus_tag="YKL197C"
/gene_synonym="PAS1"
mRNA complement(70734..73865)
/gene="PEX1"
/locus_tag="YKL197C"
/gene_synonym="PAS1"
/product="AAA family ATPase peroxin 1"
CDS complement(70734..73865)
/gene="PEX1"
/locus_tag="YKL197C"
/gene_synonym="PAS1"
/experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005778 peroxisomal
membrane [PMID:16911527]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0016562 protein
import into peroxisome matrix, receptor recycling
[PMID:16007078]"
/experiment="EXISTENCE:direct assay:GO:0043335 protein
unfolding [PMID:29321502]"
/experiment="EXISTENCE:genetic interaction:GO:0016562
protein import into peroxisome matrix, receptor recycling
[PMID:16007078]"
/experiment="EXISTENCE:mutant phenotype:GO:0016562 protein
import into peroxisome matrix, receptor recycling
[PMID:16007078]"
/experiment="EXISTENCE:mutant phenotype:GO:0016887 ATP
hydrolysis activity [PMID:15634331]"
/note="AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p
and participates in the recycling of peroxisomal signal
receptor Pex5p from the peroxisomal membrane to the
cystosol; induced by oleic acid and upregulated during
anaerobiosis; mutations in human PEX1 can lead to severe
peroxisomal disorders and early death"
/codon_start=1
/product="AAA family ATPase peroxin 1"
/protein_id="DAA08969.1"
/db_xref="SGD:S000001680"
/translation="MTTTKRLKFENLRIQFSNAIVGNFLRLPHSIINVLESTNYAIQE
FGIAVHSHNSDIPIVHLGWDGHDSGSSENVVLINPVLATVYDLNQKSPLVDLYIQRYD
HTHLATEVYVTPETSDDWEIIDANAMRFQNGEILHQTRIVTPGETLICYLEGIVTKFK
IDRVEPSMKSARITDGSLVVVAPKVNKTRLVKAEYGHSNKTILKNGAIQLLKKVILRS
TVCKMDFPKDNLFVVYISDGAQLPSQKGYASIVKCSLRQSKKSDSDNKSVGIPSKKIG
VFIKCDSQIPENHIALSSHLWDAFFTHPMNGAKIKLEFLQMNQANIISGRNATVNIKY
FGKDVPTKSGDQYSKLLGGSLLTNNLILPTEQIIIEIKKGESEQQLCNLNEISNESVQ
WKVTQMGKEEVKDIIERHLPKHYHVKETGEVSRTSKDEDDFITVNSIKKEMVNYLTSP
IIATPAIILDGKQGIGKTRLLKELINEVEKDHHIFVKYADCETLHETSNLDKTQKLIM
EWCSFCYWYGPSLIVLDNVEALFGKPQANDGDPSNNGQWDNASKLLNFFINQVTKIFN
KDNKRIRVLFSGKQKTQINPLLFDKHFVSETWSLRAPDKHARAKLLEYFFSKNQIMKL
NRDLQFSDLSLETEGFSPLDLEIFTEKIFYDLQLERDCDNVVTRELFSKSLSAFTPSA
LRGVKLTKETNIKWGDIGALANAKDVLLETLEWPTKYEPIFVNCPLRLRSGILLYGYP
GCGKTLLASAVAQQCGLNFISVKGPEILNKFIGASEQNIRELFERAQSVKPCILFFDE
FDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLDGVYILAATSRPDLIDSALLRPGRL
DKSVICNIPTESERLDILQAIVNSKDKDTGQKKFALEKNADLKLIAEKTAGFSGADLQ
GLCYNAYLKSVHRWLSAADQSEVVPGNDNIEYFSINEHGRREENRLRLKTLLQQDVVH
ETKTSTSAASELTAVVTINDLLEACQETKPSISTSELVKLRGIYDRFQKDRNGEMPNG
ENSIDIGSRLSLM"
repeat_region 74236..74518
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007055"
gene 74624..74697
/locus_tag="YNCK0003W"
tRNA 74624..74697
/locus_tag="YNCK0003W"
/product="tRNA-Asn"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Asparagine tRNA (tRNA-Asn), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006671"
gene complement(74932..75534)
/gene="YKT6"
/locus_tag="YKL196C"
mRNA complement(74932..75534)
/gene="YKT6"
/locus_tag="YKL196C"
/product="palmitoyltransferase YKT6"
CDS complement(74932..75534)
/gene="YKT6"
/locus_tag="YKL196C"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:15723044]"
/experiment="EXISTENCE:direct assay:GO:0000421
autophagosome membrane [PMID:33025734]"
/experiment="EXISTENCE:direct assay:GO:0005484 SNAP
receptor activity [PMID:11959998|PMID:33025734]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005768 endosome
[PMID:18541004]"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:18541004]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0006906 vesicle
fusion [PMID:11959998]"
/experiment="EXISTENCE:direct assay:GO:0016020 membrane
[PMID:9211930]"
/experiment="EXISTENCE:direct assay:GO:0016409
palmitoyltransferase activity [PMID:14685280]"
/experiment="EXISTENCE:direct assay:GO:0031201 SNARE
complex [PMID:11959998]"
/experiment="EXISTENCE:direct assay:GO:0061909
autophagosome-lysosome fusion [PMID:33025734]"
/experiment="EXISTENCE:mutant phenotype:GO:0006888
endoplasmic reticulum to Golgi vesicle-mediated transport
[PMID:9211930]"
/experiment="EXISTENCE:mutant phenotype:GO:0006891
intra-Golgi vesicle-mediated transport [PMID:10591633]"
/experiment="EXISTENCE:mutant phenotype:GO:0042144 vacuole
fusion, non-autophagic [PMID:10385523]"
/note="Vesicle membrane protein (v-SNARE) with
acyltransferase activity; involved in trafficking to and
within Golgi, endocytic trafficking to vacuole, and
vacuolar fusion; membrane localization due to prenylation
at carboxy-terminus; targeted to vacuole via AP-3 pathway;
human homolog YKT6 can complement yeast ykt6 mutant"
/codon_start=1
/product="palmitoyltransferase YKT6"
/protein_id="DAA08970.1"
/db_xref="SGD:S000001679"
/translation="MRIYYIGVFRSGGEKALELSEVKDLSQFGFFERSSVGQFMTFFA
ETVASRTGAGQRQSIEEGNYIGHVYARSEGICGVLITDKEYPVRPAYTLLNKILDEYL
VAHPKEEWADVTETNDALKMKQLDTYISKYQDPSQADAIMKVQQELDETKIVLHKTIE
NVLQRGEKLDNLVDKSESLTASSKMFYKQAKKSNSCCIIM"
gene 75821..77032
/gene="MIA40"
/locus_tag="YKL195W"
/gene_synonym="FMP15"
/gene_synonym="TIM40"
mRNA 75821..77032
/gene="MIA40"
/locus_tag="YKL195W"
/gene_synonym="FMP15"
/gene_synonym="TIM40"
/product="Mia40p"
CDS 75821..77032
/gene="MIA40"
/locus_tag="YKL195W"
/gene_synonym="FMP15"
/gene_synonym="TIM40"
/experiment="EXISTENCE:direct assay:GO:0003756 protein
disulfide isomerase activity [PMID:25451030]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion
[PMID:14562095|PMID:14576278|PMID:14690591|PMID:16823961|P
MID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005743
mitochondrial inner membrane
[PMID:15364952|PMID:15620710]"
/experiment="EXISTENCE:direct assay:GO:0005758
mitochondrial intermembrane space [PMID:15359280]"
/experiment="EXISTENCE:direct assay:GO:0006457 protein
folding [PMID:22990235|PMID:25451030]"
/experiment="EXISTENCE:direct assay:GO:0016972 thiol
oxidase activity [PMID:25451030]"
/experiment="EXISTENCE:direct assay:GO:0051537 2 iron, 2
sulfur cluster binding [PMID:23834247]"
/experiment="EXISTENCE:mutant phenotype:GO:0016491
oxidoreductase activity [PMID:22990235]"
/experiment="EXISTENCE:mutant phenotype:GO:0045041 protein
import into mitochondrial intermembrane space
[PMID:15359280|PMID:15364952|PMID:17336303|PMID:27343349]"
/experiment="EXISTENCE:physical interaction:GO:0045041
protein import into mitochondrial intermembrane space
[PMID:15989955]"
/note="Import and assembly protein in mitochondrial
intermembrane space; component of MIA pathway which
mediates import and oxidative folding of substrates
including small proteins containing twin cysteine motifs;
acts in concert with Erv1p, which oxidizes the cysteine
residues of Mia40p to comprise a disulfide relay system
that catalyzes import; also mediates folding of Atp23p via
a chaperone-like activity; forms a dimer that binds
iron-sulfur cluster in vitro"
/codon_start=1
/product="Mia40p"
/protein_id="DAA08971.1"
/db_xref="SGD:S000001678"
/translation="MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQ
EKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNN
SKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDES
KVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEK
SQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTE
EEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKF
QHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDV
KKEPLNEESKP"
gene complement(77258..78646)
/gene="MST1"
/locus_tag="YKL194C"
mRNA complement(77258..78646)
/gene="MST1"
/locus_tag="YKL194C"
/product="threonine--tRNA ligase MST1"
CDS complement(77258..78646)
/gene="MST1"
/locus_tag="YKL194C"
/EC_number="6.1.1.3"
/experiment="EXISTENCE:direct assay:GO:0004829
threonine-tRNA ligase activity [PMID:21321019]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion
[PMID:14576278|PMID:16823961|PMID:24769239|PMID:2999113]"
/experiment="EXISTENCE:direct assay:GO:0070159
mitochondrial threonyl-tRNA aminoacylation
[PMID:21321019]"
/experiment="EXISTENCE:mutant phenotype:GO:0004829
threonine-tRNA ligase activity [PMID:2999113]"
/note="Mitochondrial threonyl-tRNA synthetase;
aminoacylates both the canonical threonine tRNA tT(UGU)Q1
and the unusual threonine tRNA tT(UAG)Q2 in vitro; lacks a
typical editing domain, but has pre-transfer editing
activity stimulated by the unusual tRNA-Thr"
/codon_start=1
/product="threonine--tRNA ligase MST1"
/protein_id="DAA08972.1"
/db_xref="SGD:S000001677"
/translation="MKIQLVRWHCSRNALWNRAFYSTRKATKNASSATPATMTSMVSQ
RQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEK
SGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPL
HRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGS
GAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDI
MVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI
DSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHF
NVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQI
WEKFIELEKNYK"
gene complement(78866..79882)
/gene="SDS22"
/locus_tag="YKL193C"
/gene_synonym="EGP1"
mRNA complement(78866..79882)
/gene="SDS22"
/locus_tag="YKL193C"
/gene_synonym="EGP1"
/product="type 1 protein phosphatase-activating protein
SDS22"
CDS complement(78866..79882)
/gene="SDS22"
/locus_tag="YKL193C"
/gene_synonym="EGP1"
/experiment="EXISTENCE:direct assay:GO:0000164 protein
phosphatase type 1 complex [PMID:10775415]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:11801737|PMID:11914276|PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276|PMID:14562095]"
/experiment="EXISTENCE:genetic interaction:GO:0004865
protein serine/threonine phosphatase inhibitor activity
[PMID:17142459]"
/experiment="EXISTENCE:genetic interaction:GO:0072542
protein phosphatase activator activity
[PMID:11801737|PMID:18172024]"
/experiment="EXISTENCE:mutant phenotype:GO:0004865 protein
serine/threonine phosphatase inhibitor activity
[PMID:17142459]"
/experiment="EXISTENCE:mutant phenotype:GO:0007059
chromosome segregation [PMID:11801737]"
/experiment="EXISTENCE:mutant phenotype:GO:0051457
maintenance of protein location in nucleus
[PMID:11801737]"
/note="Regulatory subunit of the type 1 protein
phosphatase (PP1) Glc7p; whether it functions as a
positive or negative regulator of Glc7p is controversial;
involved in the regulation of Glc7p nuclear localization
and function"
/codon_start=1
/product="type 1 protein phosphatase-activating protein
SDS22"
/protein_id="DAA08973.1"
/db_xref="SGD:S000001676"
/translation="MDKNSVNKDSEEKDERHKIEVVDDTNPDFITADSELTQDLPDDV
EVIDLVHLKIKSLEDLNLYRFKNLKQLCLRQNLIESISEVEVLPHDKIVDLDFYDNKI
KHISSNVNKLTKLTSLDLSFNKIKHIKNLENLTDLENLYFVQNSISKIENLSTLKSLK
NLELGGNKVHSIEPDSFEGLSNLEEIWLGKNSIPRLINLHPLKNLKILSIQSNKLKKI
ENLEELTNLEELYLSHNFITKIEGLEKNLKLTTLDVTSNKITSLENLNHLSNLTDIWA
SFNKIDQSFESLGENLSALSRLETIYLEGNPIQLENKTSYRRKLTMNLPPSLQKIDAT
YIRG"
gene complement(80160..80537)
/gene="ACP1"
/locus_tag="YKL192C"
mRNA complement(80160..80537)
/gene="ACP1"
/locus_tag="YKL192C"
/product="acyl carrier protein"
CDS complement(80160..80537)
/gene="ACP1"
/locus_tag="YKL192C"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:mutant phenotype:GO:0009107 lipoate
biosynthetic process [PMID:9187370]"
/experiment="EXISTENCE:mutant phenotype:GO:0016226
iron-sulfur cluster assembly [PMID:27540631]"
/experiment="EXISTENCE:physical interaction:GO:0099128
mitochondrial iron-sulfur cluster assembly complex
[PMID:27540631]"
/note="Mitochondrial matrix acyl carrier protein; involved
in biosynthesis of octanoate, which is a precursor to
lipoic acid; coordinates mitochondrial fatty acid and iron
sulfur cluster metabolism; activated by
phosphopantetheinylation catalyzed by Ppt2p"
/codon_start=1
/product="acyl carrier protein"
/protein_id="DAA08974.1"
/db_xref="SGD:S000001675"
/translation="MFRSVCRISSRVAPSAYRTIMGRSVMSNTILAQRFYSANLSKDQ
VSQRVIDVIKAFDKNSPNIANKQISSDTQFHKDLGLDSLDTVELLVAIEEEFDIEIPD
KVADELRSVGETVDYIASNPDAN"
gene 81035..82639
/gene="DPH2"
/locus_tag="YKL191W"
mRNA 81035..82639
/gene="DPH2"
/locus_tag="YKL191W"
/product="2-(3-amino-3-carboxypropyl)histidine synthase"
CDS 81035..82639
/gene="DPH2"
/locus_tag="YKL191W"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:mutant phenotype:GO:0017183 protein
histidyl modification to diphthamide
[PMID:8406038|PMID:15485916]"
/note="Protein required for synthesis of diphthamide;
required along with Dph1p, Kti11p, Jjj3p, and Dph5p;
diphthamide is a modified histidine residue of translation
elongation factor 2 (Eft1p or Eft2p); forms a complex with
Dph1p that catalyzes the first step of diphthamide
biosynthesis"
/codon_start=1
/product="2-(3-amino-3-carboxypropyl)histidine synthase"
/protein_id="DAA08975.1"
/db_xref="SGD:S000001674"
/translation="MEVAPALSTTQSDVAFQKVETHEIDRSSYLGPCYNSDELMQLIS
AYYNVEPLVGYLEQHPEYQNVTLQFPDDLIKDSSLIVRLLQSKFPHGKIKFWVLADTA
YSACCVDEVAAEHVHAEVVVHFGDACLNAIQNLPVVYSFGTPFLDLALVVENFQRAFP
DLSSKICLMANAPFSKHLSQLYNILKGDLHYTNIIYSQVNTSAVEEKFVTILDTFHVP
EDVDQVGVFEKNSVLFGQHDKADNISPEDYHLFHLTTPQDPRLLYLSTVFQSVHIFDP
ALPGMVTGPFPSLMRRYKYMHVARTAGCIGILVNTLSLRNTRETINELVKLIKTREKK
HYLFVVGKPNVAKLANFEDIDIWCILGCSQSGIIVDQFNEFYKPIITPYELNLALSEE
VTWTGKWVVDFRDAIDEIEQNLGGQDTISASTTSDEPEFDVVRGRYTSTSRPLRALTH
LELEAADDDDSKQLTTRHTASGAVIKGTVSTSASALQNRSWKGLGSDFDSTEVDNTGA
DIEEGISGVARGYGFDREDAMKKENK"
gene 82947..83550
/gene="CNB1"
/locus_tag="YKL190W"
/gene_synonym="CRV1"
/gene_synonym="YCN2"
mRNA join(82947..82998,83075..83550)
/gene="CNB1"
/locus_tag="YKL190W"
/gene_synonym="CRV1"
/gene_synonym="YCN2"
/product="calcineurin regulatory subunit B"
CDS join(82947..82998,83075..83550)
/gene="CNB1"
/locus_tag="YKL190W"
/gene_synonym="CRV1"
/gene_synonym="YCN2"
/experiment="EXISTENCE:direct assay:GO:0004723
calcium-dependent protein serine/threonine phosphatase
activity [PMID:1321337]"
/experiment="EXISTENCE:direct assay:GO:0005509 calcium ion
binding [PMID:1321337]"
/experiment="EXISTENCE:direct assay:GO:0005955 calcineurin
complex [PMID:1321337]"
/experiment="EXISTENCE:mutant phenotype:GO:0006873
intracellular monoatomic ion homeostasis [PMID:8798496]"
/experiment="EXISTENCE:mutant phenotype:GO:0031505
fungal-type cell wall organization [PMID:7530227]"
/experiment="EXISTENCE:mutant phenotype:GO:0071444
cellular response to pheromone [PMID:1321337]"
/note="Calcineurin B; regulatory subunit of calcineurin, a
Ca++/calmodulin-regulated type 2B protein phosphatase
which regulates Crz1p (stress-response transcription
factor); other calcineurin subunit encoded by CNA1 and/or
CMP1; regulates function of Aly1p alpha-arrestin;
myristoylation by Nmt1p reduces calcineurin activity in
response to submaximal Ca signals, is needed to prevent
constitutive phosphatase activity; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="calcineurin regulatory subunit B"
/protein_id="DAA08976.1"
/db_xref="SGD:S000001673"
/translation="MGAAPSKIVDGLLEDTNFDRDEIERLRKRFMKLDRDSSGSIDKN
EFMSIPGVSSNPLAGRIMEVFDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIY
DIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEFKNAI
ETTEVAKSLTLQYDV"
repeat_region complement(83808..84115)
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007050"
gene 84208..84291
/locus_tag="YNCK0004W"
tRNA 84208..84291
/locus_tag="YNCK0004W"
/product="tRNA-Leu"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/experiment="EXISTENCE:direct assay:GO:0030371 translation
repressor activity [PMID:27609601]"
/experiment="EXISTENCE:direct assay:GO:0043022 ribosome
binding [PMID:27609601]"
/experiment="EXISTENCE:direct assay:GO:0043555 regulation
of translation in response to stress [PMID:27609601]"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006651"
gene 84704..85903
/gene="HYM1"
/locus_tag="YKL189W"
mRNA 84704..85903
/gene="HYM1"
/locus_tag="YKL189W"
/product="Hym1p"
CDS 84704..85903
/gene="HYM1"
/locus_tag="YKL189W"
/experiment="EXISTENCE:direct assay:GO:0000131 incipient
cellular bud site [PMID:12972564]"
/experiment="EXISTENCE:direct assay:GO:0005933 cellular
bud [PMID:12972564]"
/experiment="EXISTENCE:direct assay:GO:0043332 mating
projection tip [PMID:12972564]"
/experiment="EXISTENCE:genetic interaction:GO:0007118
budding cell apical bud growth [PMID:12972564]"
/experiment="EXISTENCE:mutant phenotype:GO:0000920 septum
digestion after cytokinesis [PMID:11259593]"
/experiment="EXISTENCE:mutant phenotype:GO:0006355
regulation of DNA-templated transcription [PMID:12972564]"
/experiment="EXISTENCE:mutant phenotype:GO:0007118 budding
cell apical bud growth [PMID:12972564]"
/note="Component of the RAM signaling network; is involved
in regulation of Ace2p activity and cellular
morphogenesis; interacts with Sog2p; allosterically
activates Kic1p; localizes to sites of polarized growth
during budding and during the mating response"
/codon_start=1
/product="Hym1p"
/protein_id="DAA08977.1"
/db_xref="SGD:S000001672"
/translation="MFKKYKNQDLDMAFWWKKNPKTPSDYARLIIEQLNKFSSPSLTQ
DNKRKVQEECTKYLIGTKHFIVGDTDPHPTPEAIDELYTAMHRADVFYELLLHFVDLE
FEARRECMLIFSICLGYSKDNKFVTVDYLVSQPKTISLMLRTAEVALQQKGCQDIFLT
VGNMIIECIKYEQLCRIILKDPQLWKFFEFAKLGNFEISTESLQILSAAFTAHPKLVS
KEFFSNEINIIRFIKCINKLMAHGSYVTKRQSTKLLASLIVIRSNNALMNIYINSPEN
LKLIMTLMTDKSKNLQLEAFNVFKVMVANPRKSKPVFDILVKNRDKLLTYFKTFGLDS
QDSTFLDEREFIVQEIDSLPRIISSTTEVSNNNASSSNVASITSPSSVMNNQSSILTH
STSPDSR"
gene complement(86225..88786)
/gene="PXA2"
/locus_tag="YKL188C"
/gene_synonym="PAT1"
mRNA complement(86225..88786)
/gene="PXA2"
/locus_tag="YKL188C"
/gene_synonym="PAT1"
/product="ATP-binding cassette long-chain fatty acid
transporter PXA2"
CDS complement(86225..88786)
/gene="PXA2"
/locus_tag="YKL188C"
/gene_synonym="PAT1"
/experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
[PMID:27663510]"
/experiment="EXISTENCE:direct assay:GO:0005778 peroxisomal
membrane [PMID:35127709|PMID:9395310]"
/experiment="EXISTENCE:direct assay:GO:0015867 ATP
transport [PMID:35127709]"
/experiment="EXISTENCE:direct assay:GO:0042626
ATPase-coupled transmembrane transporter activity
[PMID:9395310|PMID:35127709]"
/experiment="EXISTENCE:direct assay:GO:1902001 fatty acid
transmembrane transport [PMID:9395310]"
/note="Subunit of heterodimeric peroxisomal ABC transport
complex, with Pxa1p; required for import of long-chain
fatty acids into peroxisomes; similar to human
adrenoleukodystrophy transportesr ABCD1 and ABCD2, and
ALD-related proteins; mutations in ABCD1 cause X-linked
adrenoleukodystrophy (X-ALD), a peroxisomal disorder;
human ABCD1 and ABCD2 can each partially complement yeast
pxa1 pxa2 double null mutant"
/codon_start=1
/product="ATP-binding cassette long-chain fatty acid
transporter PXA2"
/protein_id="DAA08978.1"
/db_xref="SGD:S000001671"
/translation="MISTASAFYQKHRVNLLRSSYIILLLATLYNSNSSSSNNKTDKK
DSESTVLENKKIEEGKETAVDREEDESSKEELTIVSKHSTDSEDGAIIIDKESKTNHK
GGERKGKVDFLFKLLLHDKKCLILFITQAILLNIRTLLSLRVATLDGQLVSTLVRAQY
ANFTKILLGKWMILGIPASFINSLISYTTKLCAVTINRKVSDFLLSKYLSNHHTFYSV
ASAESVSEIQDNLTKDIYTFSMNSSLLLNQLLKPMLDLILCSFKLLTSNTSVMGEGTL
ALGLIVYASNSLLKLIQPNFTRLTMASASLESWFRSLHSNLHSSNEEIALLRGQKREL
ENVDYSFYRLVLFLNREIKARAIYDVATAFVIKYTWGAAGLVLCSIPIFFKNKPSEDT
LQLKEPGNDMTADFITNRRLLVTASSSIGRFVELKRNIQQLRGIRLRLNKFNDLLDAN
KGDDEKEPRDERCIVEYDDSRIKFENIPLITPANQVLVPELSFDLKHGNHLLIIGPNG
CGKSSLFRILGGLWPIRATPNKNHQSKLIMPRRTVDRDCAIFYLPQRPYMGNRSTFRE
QIIYPDSIEQFKERYHNDYDLGDADLIKILQLLDLEDLVTENMSLLLAQRTSKNDSQQ
LSTEDNQSPCAIKVRDAFSIVRNWSEELTIGVQQRLAMARMYYHKPKFAVLDECTSAV
APEMEQRMYENAQNFGISLISVCHRTSLWHFHNYLLKFDGKGGYQFGPFNPKERLCNE
EKLLELNAILDQQVPLWERKLKDLTIAKESNIIRKSETNLNLFEKIEDPKTSKSNALF
NANKGQRITSPTGQETSKRLPLFSQPSSSASSNLLRNNKSLNKKVKTKKEEGKER"
rep_origin 88789..89287
/note="ARS1104; Putative replication origin; identified in
multiple array studies, not yet confirmed by plasmid-based
assay"
/db_xref="SGD:S000130138"
gene complement(89284..91536)
/gene="FAT3"
/locus_tag="YKL187C"
mRNA complement(89284..91536)
/gene="FAT3"
/locus_tag="YKL187C"
/product="Fat3p"
CDS complement(89284..91536)
/gene="FAT3"
/locus_tag="YKL187C"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/experiment="EXISTENCE:mutant phenotype:GO:0015909
long-chain fatty acid transport [PMID:23349476]"
/note="Protein required for fatty acid uptake; protein
abundance increases in cortical patches in response to
oleate exposure; the authentic, non-tagged protein is
detected in a phosphorylated state in highly purified
mitochondria in high-throughput studies; FAT3 has a
paralog, YLR413W, that arose from the whole genome
duplication"
/codon_start=1
/product="Fat3p"
/protein_id="DAA08979.1"
/db_xref="SGD:S000001670"
/translation="MRIEKHRTPLSKGIIWTILSVCLLFMFTTLILVIVATAGSTANY
KPLTNIYIGEADIKHINVSKVIPQIGPILTILGSALTAPNSSLDDIFGAMKNIADTPA
LTPLLTLLSNADNTTVTIESLTELAPLAISGNPASSTRQLTEINGLLKYSDNATETLD
GLSRLVSASLSSASSNSSSDSTTLVLDLLKDSDNPQNSTDALLTLNNLTMSEKAQLLP
VFRLFAFSTNQTATMTALATLMNTTISSSLAQTLLTQLQNTISNGGSLNNTFSTLQPL
VPQASAPAFDAVELLLNQTTSTNQTLSTLSDLLEQNLTQSSSAKKAFAALTQLMENSD
NSTMVVTSVQSLAAVTNTTQSTQQLIGLDDVISSSSNTNETLSILSELQSGLSGNSSS
VQYIPYLFSLLGASTDPKTTFSSLVTLTSWAQENPQTFLPILDILADAKSVQPISAEE
LNAMTPNILEYLKIPIYYRLSIFTLCHANLENKILDCNSPHAVQNLDFRSIIYDALVT
SDFQPYLNALNISANDLYLEGKLLHREHQYVPAVRSVLALNLLAIIFSFFTMIFIILL
YFNRYMFKQPLWLIALALHVCVGVATVLAAIIISVMIAIIKSGTADDKYGVVFKAGPA
YTGLIWTAFALSFIATGLIIYTWWRNRRSGRYMSGSVTNRKGEIYTYGDGSAISADRF
GDHNLGDDDDADFEKQVNRNEITAIDNSSSANNTDVTGSTSNRTELSHPDVTPKDSNG
PVNNNAHLVA"
gene complement(92744..93298)
/gene="MTR2"
/locus_tag="YKL186C"
mRNA complement(92744..93298)
/gene="MTR2"
/locus_tag="YKL186C"
/product="Mtr2p"
CDS complement(92744..93298)
/gene="MTR2"
/locus_tag="YKL186C"
/experiment="EXISTENCE:genetic interaction:GO:0000055
ribosomal large subunit export from nucleus
[PMID:17434126]"
/experiment="EXISTENCE:mutant phenotype:GO:0000055
ribosomal large subunit export from nucleus
[PMID:17434126|PMID:31439809]"
/experiment="EXISTENCE:mutant phenotype:GO:0000056
ribosomal small subunit export from nucleus
[PMID:22956913]"
/experiment="EXISTENCE:mutant phenotype:GO:0006409 tRNA
export from nucleus [PMID:29212662]"
/experiment="EXISTENCE:mutant phenotype:GO:0008033 tRNA
processing [PMID:29212662]"
/experiment="EXISTENCE:mutant phenotype:GO:0016973
poly(A)+ mRNA export from nucleus
[PMID:7865887|PMID:9774696]"
/experiment="EXISTENCE:physical interaction:GO:0005515
protein binding [PMID:10952996]"
/experiment="EXISTENCE:physical interaction:GO:0042272
nuclear RNA export factor complex [PMID:9774696]"
/note="mRNA transport regulator; essential nuclear
protein; Mex67p and Mtr2p form a mRNA export complex which
binds to RNA"
/codon_start=1
/product="Mtr2p"
/protein_id="DAA08980.1"
/db_xref="SGD:S000001669"
/translation="MNTNSNTMVMNDANQAQITATFTKKILAHLDDPDSNKLAQFVQL
FNPNNCRIIFNATPFAQATVFLQMWQNQVVQTQHALTGVDYHAIPGSGTLICNVNCKV
RFDESGRDKMGQDATVPIQPNNTGNRNRPNDMNKPRPLWGPYFGISLQLIIDDRIFRN
DFNGVISGFNYNMVYKPEDSLLKI"
gene 94499..96265
/gene="ASH1"
/locus_tag="YKL185W"
mRNA 94499..96265
/gene="ASH1"
/locus_tag="YKL185W"
/product="DNA-binding transcription repressor ASH1"
CDS 94499..96265
/gene="ASH1"
/locus_tag="YKL185W"
/experiment="EXISTENCE:direct assay:GO:0000987
cis-regulatory region sequence-specific DNA binding
[PMID:11171979]"
/experiment="EXISTENCE:direct assay:GO:0001227 DNA-binding
transcription repressor activity, RNA polymerase
II-specific [PMID:19841732]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:8625408|PMID:8625409|PMID:9566907]"
/experiment="EXISTENCE:direct assay:GO:0005933 cellular
bud [PMID:8625408|PMID:8625409]"
/experiment="EXISTENCE:direct assay:GO:0033698 Rpd3L
complex [PMID:16286007|PMID:16314178|PMID:19040720]"
/experiment="EXISTENCE:direct assay:GO:0070210
Rpd3L-Expanded complex [PMID:19040720]"
/experiment="EXISTENCE:direct assay:GO:1900477 negative
regulation of G1/S transition of mitotic cell cycle by
negative regulation of transcription from RNA polymerase
II promoter [PMID:19841732]"
/experiment="EXISTENCE:mutant phenotype:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:8625408|PMID:8625409]"
/experiment="EXISTENCE:mutant phenotype:GO:0001227
DNA-binding transcription repressor activity, RNA
polymerase II-specific [PMID:11171979]"
/experiment="EXISTENCE:mutant phenotype:GO:1900461
positive regulation of pseudohyphal growth by positive
regulation of transcription from RNA polymerase II
promoter [PMID:11046133]"
/experiment="EXISTENCE:mutant phenotype:GO:1900477
negative regulation of G1/S transition of mitotic cell
cycle by negative regulation of transcription from RNA
polymerase II promoter [PMID:19841732]"
/note="Component of the Rpd3L histone deacetylase complex;
zinc-finger inhibitor of HO transcription; mRNA is
localized and translated in the distal tip of anaphase
cells, resulting in accumulation of Ash1p in daughter cell
nuclei and inhibition of HO expression; potential Cdc28p
substrate"
/codon_start=1
/product="DNA-binding transcription repressor ASH1"
/protein_id="DAA08981.1"
/db_xref="SGD:S000001668"
/translation="MSSLYIKTPLHALSAGPDSHANSSYYDNLLLPSFSNLSSNISRN
NITTDNNINSASPRKYSFHSLNVSPILSPISLANEILGKKSNTAPASPHHMDYNPISS
LTPGNSPEFNKASLSQISFTNPLNYGSGLGFSSNSQPRLPLLDRLSSVSLSKRPERPQ
QSLPSLRHLQLLPSPLLQENAARFPDTSKRTSNWKTDLTHWCKDTNYQDYVKIREEVA
HFKPLSIPNLTNNQNNDSFNYGKELESTRSSKFHSPSKESFDRTKLIPSILEAKDQFK
DLSNNAWSITPPVTPPMSPPTNRTMERTTLRGVEASFFEGKSSNNDSIFNPIISEKLV
QEVKHQRQLRGNSFPMPNASHKKTNSFKALQIKKLLANRDILSNNSKSNVRKPSKNKI
SKQASNVFGNTARQLVMKLDNASYSSVSASSSPSPSTPTKSGKMRSRSSSPVRPKAYT
PSPRSPNYHRFALDSPPQSPRRSSNSSITKKGSRRSSGSSPTRHTTRVCVSCHSSDSP
CWRPSWSPRKQDQLCNSCGLRYKKTHTRCLNDLCRKIPTKGEINIMKSNGIDKEFVPE
RNCEIEGYRCLFCNYITETVEN"
gene 96757..98157
/gene="SPE1"
/locus_tag="YKL184W"
/gene_synonym="ORD1"
/gene_synonym="SPE10"
mRNA 96757..98157
/gene="SPE1"
/locus_tag="YKL184W"
/gene_synonym="ORD1"
/gene_synonym="SPE10"
/product="ornithine decarboxylase SPE1"
CDS 96757..98157
/gene="SPE1"
/locus_tag="YKL184W"
/gene_synonym="ORD1"
/gene_synonym="SPE10"
/EC_number="4.1.1.17"
/experiment="EXISTENCE:direct assay:GO:0004586 ornithine
decarboxylase activity [PMID:2681188]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:mutant phenotype:GO:0009446
putrescine biosynthetic process [PMID:7929015]"
/experiment="EXISTENCE:mutant phenotype:GO:0015940
pantothenate biosynthetic process [PMID:11154694]"
/note="Ornithine decarboxylase; catalyzes the first step
in polyamine biosynthesis; degraded in a
proteasome-dependent manner in the presence of excess
polyamines; deletion decreases lifespan, and increases
necrotic cell death and ROS generation"
/codon_start=1
/product="ornithine decarboxylase SPE1"
/protein_id="DAA08982.1"
/db_xref="SGD:S000001667"
/translation="MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLE
LKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDPGEENSFFICDLGEVKRLFNNW
VKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANP
CKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYG
CEMENVDVLLKAIKELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLP
PLKILDVGGGFQFESFKESTAVLRLALEEFFPVGCGVDIIAEPGRYFVATAFTLASHV
IAKRKLSENEAMIYTNDGVYGNMNCILFDHQEPHPRTLYHNLEFHYDDFESTTAVLDS
INKTRSEYPYKVSIWGPTCDGLDCIAKEYYMKHDVIVGDWFYFPALGAYTSSAATQFN
GFEQTADIVYIDSELD"
rep_origin 98364..98523
/note="ARS1125; Autonomously Replicating Sequence"
/db_xref="SGD:S000119035"
gene complement(98395..98607)
/locus_tag="YKL183C-A"
mRNA complement(98395..98607)
/locus_tag="YKL183C-A"
/product="hypothetical protein"
CDS complement(98395..98607)
/locus_tag="YKL183C-A"
/note="hypothetical protein; identified by fungal homology
and RT-PCR"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA08983.1"
/db_xref="SGD:S000028558"
/translation="MYSKILLYRSNVLFMNFFSVFVCTIGTLFLVFADVYVLASAFFQ
SKKEKETKFKHLHYQKRSCFFLANIH"
gene 98721..99641
/gene="LOT5"
/locus_tag="YKL183W"
mRNA 98721..99641
/gene="LOT5"
/locus_tag="YKL183W"
/product="Lot5p"
CDS 98721..99641
/gene="LOT5"
/locus_tag="YKL183W"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/note="hypothetical protein; gene expression increases in
cultures shifted to a lower temperature; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="Lot5p"
/protein_id="DAA08984.1"
/db_xref="SGD:S000001666"
/translation="MMKKKPKCQIARTKPSVENVIPYNQFKKTQPRFNGNFSALNNEE
YIILFGGGRDLILGSLTPCSSSHLSNQANPQDTSEYGTDLFILNSCIIIWFNGLGYGL
EIPYSSVLYHASRRLPDGREGLQLEILLTLERDEVLDMLYQSLAPQACEFDGEEAHAF
TVRSVELTIRPKYSIYDRHYNNEIETLFTFENFGVNRGDDLVNNCNEALAVCMDLHGE
DVQDQDQEQYQDPSMAFEGAQDLNATYSGLGDTLHGPPVYQNDGLADDLDGDLVMDNV
VSRGGPEASMSMEFYANQNLAGRKNSRDNE"
gene 100671..106826
/gene="FAS1"
/locus_tag="YKL182W"
mRNA 100671..106826
/gene="FAS1"
/locus_tag="YKL182W"
/product="tetrafunctional fatty acid synthase subunit
FAS1"
CDS 100671..106826
/gene="FAS1"
/locus_tag="YKL182W"
/EC_number="1.3.1.9"
/EC_number="2.3.1.38"
/EC_number="2.3.1.39"
/EC_number="2.3.1.86"
/EC_number="3.1.2.14"
/EC_number="4.2.1.59"
/experiment="EXISTENCE:direct assay:GO:0004313
[acyl-carrier-protein] S-acetyltransferase activity
[PMID:374077]"
/experiment="EXISTENCE:direct assay:GO:0004314
[acyl-carrier-protein] S-malonyltransferase activity
[PMID:365179|PMID:374077]"
/experiment="EXISTENCE:direct assay:GO:0004319
enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific)
activity [PMID:374077]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0005811 lipid
droplet [PMID:17803462]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:6025308]"
/experiment="EXISTENCE:direct assay:GO:0005835 fatty acid
synthase complex [PMID:65153]"
/experiment="EXISTENCE:direct assay:GO:0016409
palmitoyltransferase activity [PMID:365179]"
/experiment="EXISTENCE:direct assay:GO:0019171
(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
activity [PMID:374077]"
/experiment="EXISTENCE:mutant phenotype:GO:0004312 fatty
acid synthase activity [PMID:1100391|PMID:65153]"
/experiment="EXISTENCE:mutant phenotype:GO:0004313
[acyl-carrier-protein] S-acetyltransferase activity
[PMID:1100391]"
/experiment="EXISTENCE:mutant phenotype:GO:0004314
[acyl-carrier-protein] S-malonyltransferase activity
[PMID:1100391]"
/experiment="EXISTENCE:mutant phenotype:GO:0004319
enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific)
activity [PMID:1100391]"
/experiment="EXISTENCE:mutant phenotype:GO:0016409
palmitoyltransferase activity [PMID:1100391]"
/experiment="EXISTENCE:mutant phenotype:GO:0019171
(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
activity [PMID:1100391]"
/experiment="EXISTENCE:mutant phenotype:GO:0042759
long-chain fatty acid biosynthetic process
[PMID:1735446|PMID:4127627]"
/note="Beta subunit of fatty acid synthetase; complex
catalyzes the synthesis of long-chain saturated fatty
acids; contains acetyltransacylase, dehydratase, enoyl
reductase, malonyl transacylase, and palmitoyl
transacylase activities; specific target of the
broad-spectrum antifungal NPD6433"
/codon_start=1
/product="tetrafunctional fatty acid synthase subunit
FAS1"
/protein_id="DAA08985.1"
/db_xref="SGD:S000001665"
/translation="MDAYSTRPLTLSHGSLEHVLLVPTASFFIASQLQEQFNKILPEP
TEGFAADDEPTTPAELVGKFLGYVSSLVEPSKVGQFDQVLNLCLTEFENCYLEGNDIH
ALAAKLLQENDTTLVKTKELIKNYITARIMAKRPFDKKSNSALFRAVGEGNAQLVAIF
GGQGNTDDYFEELRDLYQTYHVLVGDLIKFSAETLSELIRTTLDAEKVFTQGLNILEW
LENPSNTPDKDYLLSIPISCPLIGVIQLAHYVVTAKLLGFTPGELRSYLKGATGHSQG
LVTAVAIAETDSWESFFVSVRKAITVLFFIGVRCYEAYPNTSLPPSILEDSLENNEGV
PSPMLSISNLTQEQVQDYVNKTNSHLPAGKQVEISLVNGAKNLVVSGPPQSLYGLNLT
LRKAKAPSGLDQSRIPFSERKLKFSNRFLPVASPFHSHLLVPASDLINKDLVKNNVSF
NAKDIQIPVYDTFDGSDLRVLSGSISERIVDCIIRLPVKWETTTQFKATHILDFGPGG
ASGLGVLTHRNKDGTGVRVIVAGTLDINPDDDYGFKQEIFDVTSNGLKKNPNWLEEYH
PKLIKNKSGKIFVETKFSKLIGRPPLLVPGMTPCTVSPDFVAATTNAGYTIELAGGGY
FSAAGMTAAIDSVVSQIEKGSTFGINLIYVNPFMLQWGIPLIKELRSKGYPIQFLTIG
AGVPSLEVASEYIETLGLKYLGLKPGSIDAISQVINIAKAHPNFPIALQWTGGRGGGH
HSFEDAHTPMLQMYSKIRRHPNIMLIFGSGFGSADDTYPYLTGEWSTKFDYPPMPFDG
FLFGSRVMIAKEVKTSPDAKKCIAACTGVPDDKWEQTYKKPTGGIVTVRSEMGEPIHK
IATRGVMLWKEFDETIFNLPKNKLVPTLEAKRDYIISRLNADFQKPWFATVNGQARDL
ATMTYEEVAKRLVELMFIRSTNSWFDVTWRTFTGDFLRRVEERFTKSKTLSLIQSYSL
LDKPDEAIEKVFNAYPAAREQFLNAQDIDHFLSMCQNPMQKPVPFVPVLDRRFEIFFK
KDSLWQSEHLEAVVDQDVQRTCILHGPVAAQFTKVIDEPIKSIMDGIHDGHIKKLLHQ
YYGDDESKIPAVEYFGGESPVDVQSQVDSSSVSEDSAVFKATSSTDEESWFKALAGSE
INWRHASFLCSFITQDKMFVSNPIRKVFKPSQGMVVEISNGNTSSKTVVTLSEPVQGE
LKPTVILKLLKENIIQMEMIENRTMDGKPVSLPLLYNFNPDNGFAPISEVMEDRNQRI
KEMYWKLWIDEPFNLDFDPRDVIKGKDFEITAKEVYDFTHAVGNNCEDFVSRPDRTML
APMDFAIVVGWRAIIKAIFPNTVDGDLLKLVHLSNGYKMIPGAKPLQVGDVVSTTAVI
ESVVNQPTGKIVDVVGTLSRNGKPVMEVTSSFFYRGNYTDFENTFQKTVEPVYQMHIK
TSKDIAVLRSKEWFQLDDEDFDLLNKTLTFETETEVTFKNANIFSSVKCFGPIKVELP
TKETVEIGIVDYEAGASHGNPVVDFLKRNGSTLEQKVNLENPIPIAVLDSYTPSTNEP
YARVSGDLNPIHVSRHFASYANLPGTITHGMFSSASVRALIENWAADSVSSRVRGYTC
QFVDMVLPNTALKTSIQHVGMINGRKLIKFETRNEDDVVVLTGEAEIEQPVTTFVFTG
QGSQEQGMGMDLYKTSKAAQDVWNRADNHFKDTYGFSILDIVINNPVNLTIHFGGEKG
KRIRENYSAMIFETIVDGKLKTEKIFKEINEHSTSYTFRSEKGLLSATQFTQPALTLM
EKAAFEDLKSKGLIPADATFAGHSLGEYAALASLADVMSIESLVEVVFYRGMTMQVAV
PRDELGRSNYGMIAINPGRVAASFSQEALQYVVERVGKRTGWLVEIVNYNVENQQYVA
AGDLRALDTVTNVLNFIKLQKIDIIELQKSLSLEEVEGHLFEIIDEASKKSAVKPRPL
KLERGFACIPLVGISVPFHSTYLMNGVKPFKSFLKKNIIKENVKVARLAGKYIPNLTA
KPFQVTKEYFQDVYDLTGSEPIKEIIDNWEKYEQS"
gene 107316..108599
/gene="PRS1"
/locus_tag="YKL181W"
/gene_synonym="PRP1"
mRNA 107316..108599
/gene="PRS1"
/locus_tag="YKL181W"
/gene_synonym="PRP1"
/product="ribose phosphate diphosphokinase subunit PRS1"
CDS 107316..108599
/gene="PRS1"
/locus_tag="YKL181W"
/gene_synonym="PRP1"
/EC_number="2.7.6.1"
/experiment="EXISTENCE:direct assay:GO:0002189 ribose
phosphate diphosphokinase complex [PMID:15280369]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11101685|PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
stress granule [PMID:26777405]"
/experiment="EXISTENCE:genetic interaction:GO:0004749
ribose phosphate diphosphokinase activity [PMID:15280369]"
/experiment="EXISTENCE:genetic interaction:GO:0006015
5-phosphoribose 1-diphosphate biosynthetic process
[PMID:15280369]"
/experiment="EXISTENCE:mutant phenotype:GO:0006015
5-phosphoribose 1-diphosphate biosynthetic process
[PMID:10212224]"
/experiment="EXISTENCE:physical interaction:GO:0031505
fungal-type cell wall organization [PMID:15470112]"
/note="5-phospho-ribosyl-1(alpha)-pyrophosphate
synthetase; synthesizes PRPP, which is required for
nucleotide, histidine, and tryptophan biosynthesis; plays
a key role in cell wall integrity (CWI) pathway; one of
five related enzymes, which are active as heteromultimeric
complexes; missense mutations in human homolog PRPS1 are
associated with neuropathic Arts syndrome and
Charcot-Marie Tooth (CMTX5) disease"
/codon_start=1
/product="ribose phosphate diphosphokinase subunit PRS1"
/protein_id="DAA08986.1"
/db_xref="SGD:S000001664"
/translation="MRKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQI
GVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARKITAVIPQFPYSKQCKMKR
HRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVE
DYEDAVVVSKNPGGTKRVTALADSLKINFAMIHTDRRRSKDLYSQNKDLQQLKLRKQS
MLRKNRPIIRQGDHPNEEENIILSNGIQTARIRNGHVIGDDEADDDEDAILESDSELH
SIDGLDSHGLGGTYDAVDSEDEEEIPVLYREQLITLVGNVRGRSAIILDDMIDRPGSF
ISAAEHLVQNCGAKKVYVVATHGIFTGDCLEELEKSDAIDTIVVTNTYPISGERIAGS
KKLVTIDVSPIFAECIRRDHYGESISVLFDSLAAL"
gene 109269..110129
/gene="RPL17A"
/locus_tag="YKL180W"
/gene_synonym="RPL17"
mRNA join(109269..109577,109884..110129)
/gene="RPL17A"
/locus_tag="YKL180W"
/gene_synonym="RPL17"
/product="ribosomal 60S subunit protein L17A"
CDS join(109269..109577,109884..110129)
/gene="RPL17A"
/locus_tag="YKL180W"
/gene_synonym="RPL17"
/experiment="EXISTENCE:direct assay:GO:0002181 cytoplasmic
translation [PMID:18782943]"
/experiment="EXISTENCE:direct assay:GO:0003735 structural
constituent of ribosome [PMID:18782943]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276]"
/experiment="EXISTENCE:direct assay:GO:0022625 cytosolic
large ribosomal subunit [PMID:18782943]"
/experiment="EXISTENCE:direct assay:GO:0030687
preribosome, large subunit precursor [PMID:23268442]"
/experiment="EXISTENCE:genetic interaction:GO:0000448
cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of
tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA) [PMID:23268442]"
/note="Ribosomal 60S subunit protein L17A; required for
processing of 27SB pre-rRNA and formation of stable 66S
assembly intermediates; copurifies with the Dam1 complex
(aka DASH complex); homologous to mammalian ribosomal
protein L17 and bacterial L22; RPL17A has a paralog,
RPL17B, that arose from the whole genome duplication;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="ribosomal 60S subunit protein L17A"
/protein_id="DAA08987.1"
/db_xref="SGD:S000001663"
/translation="MARYGATSTNPAKSASARGSYLRVSFKNTRETAQAINGWELTKA
QKYLEQVLDHQRAIPFRRFNSSIGRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAANA
EAKGLDATKLYVSHIQVNQAPKQRRRTYRAHGRINKYESSPSHIELVVTEKEEAVAKA
AEKKVVRLTSRQRGRIAAQKRIAA"
gene complement(110464..112503)
/gene="COY1"
/locus_tag="YKL179C"
mRNA complement(110464..112503)
/gene="COY1"
/locus_tag="YKL179C"
/product="Coy1p"
CDS complement(110464..112503)
/gene="COY1"
/locus_tag="YKL179C"
/experiment="EXISTENCE:direct assay:GO:0000139 Golgi
membrane [PMID:31073031]"
/experiment="EXISTENCE:direct assay:GO:0000149 SNARE
binding [PMID:31073031]"
/experiment="EXISTENCE:direct assay:GO:0048211 Golgi
vesicle docking [PMID:31073031]"
/experiment="EXISTENCE:genetic interaction:GO:0000139
Golgi membrane [PMID:12429822]"
/experiment="EXISTENCE:genetic interaction:GO:0048193
Golgi vesicle transport [PMID:12429822]"
/note="Golgi membrane protein with similarity to mammalian
CASP; packaged into COPII vesicles for trafficking between
ER and Golgi; genetic interactions with GOS1 (encoding a
Golgi snare protein) suggest a role in Golgi function"
/codon_start=1
/product="Coy1p"
/protein_id="DAA08988.1"
/db_xref="SGD:S000001662"
/translation="MDTSVYSHALDIWAKADLTNLQRELDADVIEIKDKETLSLNSRK
SLATETKKFKKLEPEEKLNNVNKIIKQYQREIDNLTQRSKFSEKVLFDVYEKLSEAPD
PQPLLQSSLEKLGKIDDSKELKEKISYLEDKLAKYADYETLKSRLLDLEQSSAKTLAK
RLTAKTQEINSTWEEKGRNWKEREADLLKQLTNVQEQNKALEAKISKNIDIEGNGNED
GDQENNQKEVSTRIAEYNLVTQELETTQARIYQLEKRNEELSGALAKATSEAEKETEL
HAKELKLNQLESENALLSASYEQERKSTSHAINELKEQLNSVVAESESYKSELETVRR
KLNNYSDYNKIKEELSALKKIEFGVNEDDSDNDIRSEDKNDNTFESSLLSANKKLQAT
LAEYRSKSTAQEEERNELKKSVDQLKQQIATLKEANEKLETDLEKVENVSPHFNETAS
MMSGVTRQMNNRTSHKMSPTSSIIGIPEDGELSGNQSTILPIVTKQRDRFRSRNMDLE
KQLRQGNSEKGKLKLEISKLKGDNTKLYERIRYLQSYNNNNAPVNQSTERIDVESQYS
RVYDESLHPMANFRQNELNHYKNKKLSALEKLFSSFAKVILQNKMTRMVFLFYCIGLH
GLVFMMSMYVINISGYMTPEVGIVQSAKSSSNLNGGLGGAEKVAAGVGSVHGINR"
gene complement(113215..114627)
/gene="STE3"
/locus_tag="YKL178C"
/gene_synonym="DAF2"
mRNA complement(113215..114627)
/gene="STE3"
/locus_tag="YKL178C"
/gene_synonym="DAF2"
/product="Ste3p"
CDS complement(113215..114627)
/gene="STE3"
/locus_tag="YKL178C"
/gene_synonym="DAF2"
/experiment="EXISTENCE:direct assay:GO:0000755 cytogamy
[PMID:17369365]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:3006051]"
/experiment="EXISTENCE:mutant phenotype:GO:0000750
pheromone-dependent signal transduction involved in
conjugation with cellular fusion [PMID:3006051]"
/experiment="EXISTENCE:mutant phenotype:GO:0000755
cytogamy [PMID:17369365]"
/experiment="EXISTENCE:mutant phenotype:GO:0004933
mating-type a-factor pheromone receptor activity
[PMID:3006051]"
/note="Receptor for a factor pheromone; couples to MAP
kinase cascade to mediate pheromone response; transcribed
in alpha cells and required for mating by alpha cells,
ligand bound receptors endocytosed and recycled to the
plasma membrane; GPCR"
/codon_start=1
/product="Ste3p"
/protein_id="DAA08989.1"
/db_xref="SGD:S000001661"
/translation="MSYKSAIIGLCLLAVILLAPPLAWHSHTKNIPAIILITWLLTMN
LTCIVDAAIWSDDDFLTRWDGKGWCDIVIKLQVGANIGISCAVTNIIYNLHTILKADS
VLPDLSSWTKIVKDLVISLFTPVMVMGFSYLLQVFRYGIARYNGCQNLLSPTWITTVL
YTMWMLIWSFVGAVYATLVLFVFYKKRKDVRDILHCTNSGLNLTRFARLLIFCFIIIL
VMFPFSVYTFVQDLQQVEGHYTFKNTHSSTIWNTIIKFDPGRPIYNIWLYVLMSYLVF
LIFGLGSDALHMYSKFLRSIKLGFVLDMWKRFIDKNKEKRVGILLNKLSSRKESRNPF
STDSENYISTCTENYSPCVGTPISQAHFYVDYRIPDDPRKSQNKSKKYLFADKETDDI
LDEIDLKESRHIPYVTQGQSFDDEISLGGFSKVTLDYSEKLHNSASSNFEGESLCYSP
ASKEENSSSNEHSSENTAGP"
gene complement(115500..117986)
/gene="LST4"
/locus_tag="YKL176C"
mRNA complement(115500..117986)
/gene="LST4"
/locus_tag="YKL176C"
/product="Lst4p"
CDS complement(115500..117986)
/gene="LST4"
/locus_tag="YKL176C"
/experiment="EXISTENCE:direct assay:GO:0005096 GTPase
activator activity [PMID:26387955]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:26387955]"
/experiment="EXISTENCE:direct assay:GO:0005774 vacuolar
membrane [PMID:26387955]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:1990877
FNIP-folliculin RagC/D GAP [PMID:26387955]"
/experiment="EXISTENCE:mutant phenotype:GO:1904263
positive regulation of TORC1 signaling [PMID:26387955]"
/note="Subunit of the Lst4p-Lst7p GTPase activating
protein complex for Gtr2p; stimulates the GTPase activity
of Rag family GTPase Gtr2p, within the context of the
Gtr1p-Gtr2p heterodimer, after amino acid stimulation;
required for activation of TORC1 in response to amino acid
stimulation; recruited to the vacuolar membrane during
amino acid starvation and released from the membrane by
TORC1; required for the transport of amino acid permease
Gap1p from the Golgi to the cell surface"
/codon_start=1
/product="Lst4p"
/protein_id="DAA08990.1"
/db_xref="SGD:S000001659"
/translation="MLGNLLRNKTSSSGFEKSSEHSDFSSVVPNVPVYCKAASTGTTK
TAAGALLDTAVNVEKPSEMLSTTSPPILDHISDDLKLKLFGSRDIPYSRPIDTLQNNG
GLGTDKITSINEKTYAFRILIIEEAGQMACRNNYRDIFDYTTSKISNSMEQIRPSELK
EYIFGSPVRSSDLTQCDKIRTIPNSDLVLITRIFYYTHQYNRIAISLCIPRILLPVVA
ESWSSISSWLTQTQKMLIGFLTKNRIMQENTGNYSNNSVIKLSNIDIRTHYPKEIEIM
VQTLQKRVIPGLRSMSEIPRLFLYPETFKEFVHVWFKSIFNWIEIKDGPKLGFLPLLM
AMIISDYRHTIRELKTSKIVILSGNMVVANKLLFILSALLEPKYKGQITIRRENIRSD
SSAVSRNKSNNNFVDKPETELSTLTSTDNLLSRTENNSNHNYNNSNVSSNSIGSPNFH
SLRKGWQIPNRRNSNTSVSVSSSESLAEVIQPSSFKSGSSSLHYLSSSISSQPGSYGS
WFNKRPTISQFFQPSPSLKHNESWERLQTTAGNMQRTSSSSSLQQATSRLSLTTPQQS
PSISEYDEYPWMGTPGSPNVGDVSHAPPLVKNISYKFPLKNVELKRDCQRISQDDLLD
EAFERICQPSLADLNSTYEIFPGNSSYADILTTDSDIDDGLMNKPLELLPKYTMYLTH
FNNFFQLQACPAGQESESRITNSMKIDLLKADYTRSLLVSLRSRDIRDVALKREFTGN
NNNNSNQNIYDENFVGKRKYVLKQKTRKIFSCGKIGKLSTSLENCVNFVENSIKSAMM
LYDDNGIDSELRDSEALRIFSSLVHYCNAG"
gene 118793..120304
/gene="ZRT3"
/locus_tag="YKL175W"
mRNA 118793..120304
/gene="ZRT3"
/locus_tag="YKL175W"
/product="Zn(2+) transporter ZRT3"
CDS 118793..120304
/gene="ZRT3"
/locus_tag="YKL175W"
/experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
vacuole membrane [PMID:10856230]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:mutant phenotype:GO:0005385 zinc
ion transmembrane transporter activity [PMID:10856230]"
/experiment="EXISTENCE:mutant phenotype:GO:0006829 zinc
ion transport [PMID:10856230]"
/experiment="EXISTENCE:mutant phenotype:GO:0006882
intracellular zinc ion homeostasis [PMID:10856230]"
/note="Vacuolar membrane zinc transporter; transports zinc
from storage in vacuole to cytoplasm when needed;
transcription induced under conditions of zinc deficiency;
targeted to vacuole via AP-3 pathway"
/codon_start=1
/product="Zn(2+) transporter ZRT3"
/protein_id="DAA08991.1"
/db_xref="SGD:S000001658"
/translation="MEKIPRWLLFSLISSVLCILGALCVPLLSVAFDSKRNSQSKLVN
YGLSLSAGSMITTSLYMLLPRIEKSNRFKVFPGLLLGICLSFFLNYLVHAFASESLVH
CADSGDHATGSHIHSKSHSHSHSHSHADSHSNFSNDHDLENAPSEHGYATSSSSVSEN
DPLITKDSDRPQMKKKMSLIDLLTRRKSEGECCDLNKCTPLLQSEQPEYIACVPPVIK
SSQSERNVPHGCEGSEDNGQSDDKDHRGLVCVENNIGYDLENLSLYRKNFLSSRHHHS
SESPENYGSNQLSHSFSSPLGNDVTENPAALADTQYHPENGSLYPHHHHLETPFSKLL
SIGMQTCLVLALHKFPEGFIIFYTNRSDSSKSLGFSIFLSLTIHNFVEGFAMTLPFYT
VFESKWVAILITAVLGGGSQPLGALIGYFIFKGSTPRDHEPNMDFLLSVTAGFLLVIG
LQMFQTGIGFSDGHHHHQGEGDEEMKQSHSSGTTCLKWCCTGVLLILASALFT"
gene complement(120380..122236)
/gene="TPO5"
/locus_tag="YKL174C"
mRNA complement(120380..122236)
/gene="TPO5"
/locus_tag="YKL174C"
/product="Tpo5p"
CDS complement(120380..122236)
/gene="TPO5"
/locus_tag="YKL174C"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:15668236]"
/experiment="EXISTENCE:mutant phenotype:GO:0015203
polyamine transmembrane transporter activity
[PMID:15668236]"
/experiment="EXISTENCE:mutant phenotype:GO:0015846
polyamine transport [PMID:15668236]"
/note="Protein involved in excretion of putrescine and
spermidine; putative polyamine transporter in the Golgi or
post-Golgi vesicles"
/codon_start=1
/product="Tpo5p"
/protein_id="DAA08992.1"
/db_xref="SGD:S000001657"
/translation="MPEYTLLADNIRENIVHFDPNGLFDNLHTIVHEDDSQENEEAEH
FNYDQVLDKSLLSRGSIVGLGLGLMSPVLGMCTSMAIGLINGGPLTIMLGFLISGVCI
WFSSLSLGEIVSKFPMELHVGSAMLAPEKLKLVCSWYTGWLMLIGNWTMSTSITFAGA
QLTISLILMTNSNLISEAHLIFYTVIVFYLVVTVVGLVNLKFARFIETINKVCVYWII
YAIIFIDILLLVFHKGKFRSLKYALFHFDNNLSGYKSAFLSFIIGFQQSNFTLQGFSM
LPALADEVKVPEKDIPRGMSNAVLLSAFSGVIFLIPIMLILPDNDLLFTNHKVLPIVN
IFTKSTDSVVLSFFLVLLILGNLLFSGIGSITTSSRAVYSFSRDQAIPYYDKWTYVEP
DSQSKVPKNSVVLSMIISYFLGLLALISTAAFNAFIGAAVLCLCSATFIPLVLVLFTR
RRAIRSAPVKIRYKFGWFINIVSIVWLLLSMVSVCLPTQVPVTFKTMNYALMVYVFCI
LVITGLYFKWGKYNFRLPLADDIKAPIPSDAEETVFELEDSNVEHTLNSGTTVKESVE
NNSEEGFIKVHPKSSTENPFEENEENVITDYGDEHHTAEQEFDLADDRRYDI"
gene 122517..125543
/gene="SNU114"
/locus_tag="YKL173W"
/gene_synonym="GIN10"
mRNA 122517..125543
/gene="SNU114"
/locus_tag="YKL173W"
/gene_synonym="GIN10"
/product="U5 snRNP GTPase SNU114"
CDS 122517..125543
/gene="SNU114"
/locus_tag="YKL173W"
/gene_synonym="GIN10"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005682 U5 snRNP
[PMID:11720284|PMID:11720285]"
/experiment="EXISTENCE:direct assay:GO:0030623 U5 snRNA
binding [PMID:9848662]"
/experiment="EXISTENCE:direct assay:GO:0046540 U4/U6 x U5
tri-snRNP complex [PMID:10377396|PMID:10449419]"
/experiment="EXISTENCE:genetic interaction:GO:0000349
generation of catalytic spliceosome for first
transesterification step [PMID:15911574]"
/experiment="EXISTENCE:mutant phenotype:GO:0000244
spliceosomal tri-snRNP complex assembly [PMID:16540695]"
/experiment="EXISTENCE:mutant phenotype:GO:0000388
spliceosome conformational change to release U4 (or
U4atac) and U1 (or U11) [PMID:16540695]"
/experiment="EXISTENCE:mutant phenotype:GO:0000398 mRNA
splicing, via spliceosome [PMID:9233818]"
/experiment="EXISTENCE:mutant phenotype:GO:0003924 GTPase
activity [PMID:9233818]"
/note="GTPase component of U5 snRNP involved in mRNA
splicing via spliceosome; binds directly to U5 snRNA;
proposed to be involved in conformational changes of the
spliceosome; similarity to ribosomal translocation factor
EF-2"
/codon_start=1
/product="U5 snRNP GTPase SNU114"
/protein_id="DAA08993.1"
/db_xref="SGD:S000001656"
/translation="MEGDDLFDEFGNLIGVDPFDSDEEESVLDEQEQYQTNTFEGSGN
NNEIESRQLTSLGSKKELGISLEHPYGKEVEVLMETKNTQSPQTPLVEPVTERTKLQE
HTIFTQLKKNIPKTRYNRDYMLSMANIPERIINVGVIGPLHSGKTSLMDLLVIDSHKR
IPDMSKNVELGWKPLRYLDNLKQEIDRGLSIKLNGSTLLCTDLESKSRMINFLDAPGH
VNFMDETAVALAASDLVLIVIDVVEGVTFVVEQLIKQSIKNNVAMCFVINKLDRLILD
LKLPPMDAYLKLNHIIANINSFTKGNVFSPIDNNIIFASTKLGFTFTIKEFVSYYYAH
SIPSSKIDDFTTRLWGSVYYHKGNFRTKPFENVEKYPTFVEFILIPLYKIFSYALSME
KDKLKNLLRSNFRVNLSQEALQYDPQPFLKHVLQLIFRQQTGLVDAITRCYQPFELFD
NKTAHLSIPGKSTPEGTLWAHVLKTVDYGGAEWSLVRIYSGLLKRGDTVRILDTSQSE
SRQKRQLHDISKTETSNEDEDEDDETPSCEVEEIGLLGGRYVYPVHEAHKGQIVLIKG
ISSAYIKSATLYSVKSKEDMKQLKFFKPLDYITEAVFKIVLQPLLPRELPKLLDALNK
ISKYYPGVIIKVEESGEHVILGNGELYMDCLLYDLRASYAKIEIKISDPLTVFSESCS
NESFASIPVSNSISRLGEENLPGLSISVAAEPMDSKMIQDLSRNTLGKGQNCLDIDGI
MDNPRKLSKILRTEYGWDSLASRNVWSFYNGNVLINDTLPDEISPELLSKYKEQIIQG
FYWAVKEGPLAEEPIYGVQYKLLSISVPSDVNIDVMKSQIIPLMKKACYVGLLTAIPI
LLEPIYEVDITVHAPLLPIVEELMKKRRGSRIYKTIKVAGTPLLEVRGQVPVIESAGF
ETDLRLSTNGLGMCQLYFWHKIWRKVPGDVLDKDAFIPKLKPAPINSLSRDFVMKTRR
RKGISTGGFMSNDGPTLEKYISAELYAQLRENGLVP"
gene 125759..127042
/gene="EBP2"
/locus_tag="YKL172W"
mRNA 125759..127042
/gene="EBP2"
/locus_tag="YKL172W"
/product="Ebp2p"
CDS 125759..127042
/gene="EBP2"
/locus_tag="YKL172W"
/experiment="EXISTENCE:direct assay:GO:0003729 mRNA
binding [PMID:23222640]"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:10849420]"
/experiment="EXISTENCE:direct assay:GO:0030687
preribosome, large subunit precursor
[PMID:11583614|PMID:17443350]"
/experiment="EXISTENCE:direct assay:GO:0034399 nuclear
periphery [PMID:21822217]"
/experiment="EXISTENCE:mutant phenotype:GO:0000280 nuclear
division [PMID:15515129]"
/experiment="EXISTENCE:mutant phenotype:GO:0006364 rRNA
processing [PMID:10849420]"
/note="Protein required for 25S rRNA maturation and 60S
ribosomal subunit assembly; localizes to the nucleolus and
in foci along nuclear periphery; constituent of 66S
pre-ribosomal particles; cooperates with Rrs1p and Mps3p
to mediate telomere clustering by binding Sir4p, but is
not involved in telomere tethering"
/codon_start=1
/product="Ebp2p"
/protein_id="DAA08994.1"
/db_xref="SGD:S000001655"
/translation="MAKGFKLKELLSHQKEIEKAEKLENDLKKKKSQELKKEEPTIVT
ASNLKKLEKKEKKADVKKEVAADTEEYQSQALSKKEKRKLKKELKKMQEQDATEAQKH
MSGDEDESGDDREEEEEEEEEEEGRLDLEKLAKSDSESEDDSESENDSEEDEDVVAKE
ESEEKEEQEEEQDVPLSDVEFDSDADVVPHHKLTVNNTKAMKHALERVQLPWKKHSFQ
EHQSVTSETNTDEHIKDIYDDTERELAFYKQSLDAVLVARDELKRLKVPFKRPLDYFA
EMVKSDEHMDKIKGKLIEEASDKKAREEARRQRQLKKFGKQVQNATLQKRQLEKRETL
EKIKSLKNKRKHNEIDHSEFNVGVEEEVEGKRFDRGRPNGKRAAKNAKYGQGGMKRFK
RKNDATSSADVSGFSSRKMKGKTNRPGKSRRARRF"
gene 127475..130261
/gene="NNK1"
/locus_tag="YKL171W"
mRNA 127475..130261
/gene="NNK1"
/locus_tag="YKL171W"
/product="protein kinase NNK1"
CDS 127475..130261
/gene="NNK1"
/locus_tag="YKL171W"
/EC_number="2.7.11.1"
/experiment="EXISTENCE:direct assay:GO:0004672 protein
kinase activity [PMID:16319894]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276|PMID:22289182]"
/experiment="EXISTENCE:direct assay:GO:0006468 protein
phosphorylation [PMID:16319894]"
/experiment="EXISTENCE:mutant phenotype:GO:0006508
proteolysis [PMID:11595789]"
/note="Protein kinase; implicated in proteasome function;
interacts with TORC1, Ure2 and Gdh2; overexpression leads
to hypersensitivity to rapamycin and nuclear accumulation
of Gln3; epitope-tagged protein localizes to the
cytoplasm"
/codon_start=1
/product="protein kinase NNK1"
/protein_id="DAA08995.1"
/db_xref="SGD:S000001654"
/translation="MFTSQRQLRQNGSPMSSSRSSQHSSGTASPISDSPASNRSYGRD
LRGLMGIDIPANEPAFNRANSSDTIYFRPKKIYKMEHEHPSRSTLVQLQTRSQPDDVA
SSQVNPEGGTDDLELGDPCGNQSLYTIGAEYVPDLDFTKLVNEWQKSTEDLYEFRSSA
TPQVQIKDSGKGNYELWSSPDAILTQNKLRRDSFSQENSDSLSPEDSILSRNLHSKVK
PIPLPRNSQQIFTPLSNLEAERRSSYTTSSNNNSITQNNKFSFAKLKYSLPTQSSAVP
ASFDSNASSLNFLPTTTLSTLSELQISPNDMMDLIQKLPRNFLNLPYTQRKKVIIEHA
PSHDYKAMMSLVKKFMLTSSRSNFSLAGFANNASVSQATANDDNINSRNTPNNSNDTY
VNTRPLQRSRHGSIASQFLSSFSPSMTSIAKMNSNPLSGSAGGSARPDDKGMEILGHR
LGKIIGFGAWGIIRECFDIETGVGRVIKIVKFKGHQNIKKHVLREVAIWRTLKHNRIL
PLLDWKLDDNYAMYCLTERINDGTLYDLVISWDEFKRSKIPFAERCRLTIFLSLQLLS
ALKYMHSKTIVHGDIKLENCLLQKEGKKSDWKVFLCDFGMSCHFDEKHVYRNDTFDEN
LSSGNSHRKRKSIEQTNLIKYPTTNFLPDDRTNDFDASENLKYQFENRKHQPFTPKGM
VSSSSHSLKHLNQPSSSSSSNLFHKPASQPQPQHRSPFHGRHKTTDFSNLEPEPSKYI
GSLPYASPELLRYSDARRSKSVEMHIYDSPDSSQSEISAASSSSSNLSSLSSSTKASA
VTNSGVTTSSPSGSSTDFPCIVSPLGPASDIWALGVMLYTMLVGKLPFNHEFEPRLRS
LIKVGEFDRFSLAQVCKFDRKKNEGTIGQGLYDTVIGCLTIDLDKRWKLKRIEEVLQN
EMNLSEAIHDNNGS"
gene 130634..131050
/gene="MRPL38"
/locus_tag="YKL170W"
/gene_synonym="uL14m"
mRNA 130634..131050
/gene="MRPL38"
/locus_tag="YKL170W"
/gene_synonym="uL14m"
/product="mitochondrial 54S ribosomal protein YmL38/YmL34"
CDS 130634..131050
/gene="MRPL38"
/locus_tag="YKL170W"
/gene_synonym="uL14m"
/experiment="EXISTENCE:curator inference:GO:0032543
mitochondrial translation [PMID:12392552|PMID:9151978]"
/experiment="EXISTENCE:direct assay:GO:0003735 structural
constituent of ribosome [PMID:12392552|PMID:9151978]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005762
mitochondrial large ribosomal subunit
[PMID:12392552|PMID:9151978]"
/note="Mitochondrial ribosomal protein of the large
subunit; appears as two protein spots (YmL34 and YmL38) on
two-dimensional SDS gels; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL38/YmL34"
/protein_id="DAA08996.1"
/db_xref="SGD:S000001653"
/translation="MIFLKSVIKVIDNSGAQLAECIKVIRKGSPKSPAMVGDRIVCVI
QKAKPLTQNITGTANTNRVKKGDICHAIVVRSKQRNMCRKDGSTVAFGDTACVLINKN
TGEPLGTRIMANDGCVDRTLKDKGYNKICSLASRVI"
gene complement(131288..133462)
/gene="KKQ8"
/locus_tag="YKL168C"
mRNA complement(131288..133462)
/gene="KKQ8"
/locus_tag="YKL168C"
/product="putative serine/threonine protein kinase KKQ8"
CDS complement(131288..133462)
/gene="KKQ8"
/locus_tag="YKL168C"
/EC_number="2.7.11.1"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095|PMID:22289182]"
/note="Putative serine/threonine protein kinase with
unknown cellular role; KKQ8 has a paralog, HAL5, that
arose from the whole genome duplication"
/codon_start=1
/product="putative serine/threonine protein kinase KKQ8"
/protein_id="DAA08997.1"
/db_xref="SGD:S000001651"
/translation="MVMQEEKKRQQPVTRRVRSFSESFKNLFRPPRSRDSSPINVTRI
PYRSSSTSPKRSSEPPRRSTVSAQILDPKNSPIRQRSYTLKCCTPGLSHPFRQTGSGA
SNSPTRHRSISGEEQEIVNSLPEYKRSASHTFHGIRRPRSRSSSVSSCDSSNGTTSSS
DSQWAMDSLLDDSDNDLTPYRGSNKDILKSKDRAPYNYIDDYNKKALRRATSYPNPLP
SKQFYNERLYTRRSHPDEESLESLPRFAGADVQCIIEQNGFKVYEDGSHEHNIKLSGV
IAKLEKGNSLPAHRQGSLSRPRLGITLSGLFKHHKNECDIENALSLLPNVEKSQTNHE
KRTGQSPNDSNRSSPTQGREDYLKIVNPDASLGSDELKLINSLSSRIHKSLQNYLQEK
NLKPAECIGEQAPTFQDNYGHPVGLVGAGAYGEVKLCARLRNEKDSPPFETYHDSKYI
YYAVKELKPKPDSDLEKFCTKITSEFIIGHSLSHYHKNGKKPAPNILNVFDILEDSSS
FIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKP
ENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRL
IDCWSCGVVYITMILGHYLWKVASREKDMSYDEFYKEMQRKNQFRVFEELKHVNSELA
TNRKIALYRIFQWEPRKRISVGKLLDMQWMKSTNCCLIYDST"
gene complement(133721..134134)
/gene="MRP49"
/locus_tag="YKL167C"
/gene_synonym="mL61"
mRNA complement(133721..134134)
/gene="MRP49"
/locus_tag="YKL167C"
/gene_synonym="mL61"
/product="mitochondrial 54S ribosomal protein MRP49"
CDS complement(133721..134134)
/gene="MRP49"
/locus_tag="YKL167C"
/gene_synonym="mL61"
/experiment="EXISTENCE:direct assay:GO:0003735 structural
constituent of ribosome [PMID:1544898]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0005762
mitochondrial large ribosomal subunit [PMID:1544898]"
/experiment="EXISTENCE:mutant phenotype:GO:0032543
mitochondrial translation [PMID:1544898]"
/note="Mitochondrial ribosomal protein of the large
subunit; not essential for mitochondrial translation"
/codon_start=1
/product="mitochondrial 54S ribosomal protein MRP49"
/protein_id="DAA08998.1"
/db_xref="SGD:S000001650"
/translation="MSKVAQQLKFLNKISATTRLPQILVDPKKYSGLRLTFQTKNHNG
HMGARVFWHNYLPTLQFYNPRMKFDVIRIKNEDKQKSVPCKLEILSHEGSVVETIDMR
NKMHEDIMKDLLDKIEHVPLPENEIIRVGPQESII"
gene complement(134509..135705)
/gene="TPK3"
/locus_tag="YKL166C"
mRNA complement(134509..135705)
/gene="TPK3"
/locus_tag="YKL166C"
/product="cAMP-dependent protein kinase catalytic subunit
TPK3"
CDS complement(134509..135705)
/gene="TPK3"
/locus_tag="YKL166C"
/EC_number="2.7.11.11"
/experiment="EXISTENCE:direct assay:GO:0000932 P-body
[PMID:22899713]"
/experiment="EXISTENCE:direct assay:GO:0004672 protein
kinase activity [PMID:16319894]"
/experiment="EXISTENCE:direct assay:GO:0004691
cAMP-dependent protein kinase activity [PMID:3036373]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095|PMID:19804918]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095|PMID:19804918]"
/experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
stress granule [PMID:22899713]"
/experiment="EXISTENCE:genetic interaction:GO:0004691
cAMP-dependent protein kinase activity [PMID:3036373]"
/experiment="EXISTENCE:genetic interaction:GO:0005952
cAMP-dependent protein kinase complex [PMID:3036373]"
/experiment="EXISTENCE:genetic interaction:GO:0007005
mitochondrion organization [PMID:19897478]"
/experiment="EXISTENCE:genetic interaction:GO:0007265 Ras
protein signal transduction [PMID:3036373]"
/experiment="EXISTENCE:genetic interaction:GO:0010607
negative regulation of cytoplasmic mRNA processing body
assembly [PMID:21925385]"
/experiment="EXISTENCE:genetic interaction:GO:0010737
protein kinase A signaling [PMID:20133652]"
/experiment="EXISTENCE:mutant phenotype:GO:0004691
cAMP-dependent protein kinase activity [PMID:3036373]"
/experiment="EXISTENCE:mutant phenotype:GO:0007005
mitochondrion organization [PMID:19897478]"
/experiment="EXISTENCE:mutant phenotype:GO:2000766
negative regulation of cytoplasmic translation
[PMID:22899713]"
/note="cAMP-dependent protein kinase catalytic subunit;
promotes vegetative growth in response to nutrients via
the Ras-cAMP signaling pathway; partially redundant with
Tpk1p and Tpk2p; localizes to P-bodies during stationary
phase; TPK3 has a paralog, TPK1, that arose from the whole
genome duplication"
/codon_start=1
/product="cAMP-dependent protein kinase catalytic subunit
TPK3"
/protein_id="DAA08999.1"
/db_xref="SGD:S000001649"
/translation="MYVDPMNNNEIRKLSITAKTETTPDNVGQDIPVNAHSVHEECSS
NTPVEINGRNSGKLKEEASAGICLVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRV
HLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQ
VFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENIL
LDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEM
LAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSE
DVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEFNYGIQGEDPYM
DLMKEF"
gene complement(137932..140691)
/gene="MCD4"
/locus_tag="YKL165C"
/gene_synonym="FSR2"
/gene_synonym="SSU21"
/gene_synonym="ZRG16"
mRNA complement(137932..140691)
/gene="MCD4"
/locus_tag="YKL165C"
/gene_synonym="FSR2"
/gene_synonym="SSU21"
/gene_synonym="ZRG16"
/product="mannose-ethanolamine phosphotransferase MCD4"
CDS complement(137932..140691)
/gene="MCD4"
/locus_tag="YKL165C"
/gene_synonym="FSR2"
/gene_synonym="SSU21"
/gene_synonym="ZRG16"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:10514566]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:10069808|PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0006506 GPI anchor
biosynthetic process [PMID:12023081]"
/experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
cell wall [PMID:12023081]"
/experiment="EXISTENCE:direct assay:GO:0015867 ATP
transport [PMID:12807869]"
/experiment="EXISTENCE:mutant phenotype:GO:0006506 GPI
anchor biosynthetic process [PMID:17311586|PMID:16704983]"
/experiment="EXISTENCE:mutant phenotype:GO:0051377
mannose-ethanolamine phosphotransferase activity
[PMID:17311586|PMID:16704983]"
/note="Protein involved in GPI anchor synthesis;
multimembrane-spanning protein that localizes to the
endoplasmic reticulum; highly conserved among eukaryotes;
GPI stands for glycosylphosphatidylinositol"
/codon_start=1
/product="mannose-ethanolamine phosphotransferase MCD4"
/protein_id="DAA09000.1"
/db_xref="SGD:S000001648"
/translation="MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTP
TPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPT
ESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGAS
DPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFL
HLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSA
FGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIAS
LMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFF
YKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTY
NWRFIRTIVTFGFVGWIFFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWIL
FYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYE
GIVYGFFHRWTFTLITNILAFYPFICGVRELSVNILWIITSVLLSTFTLFDAVKIEDL
NQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQ
GLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFESL
FYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASIS
SFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIIS
MSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKNVIIQDK
TKKTQ"
gene complement(141018..141089)
/locus_tag="YNCK0005C"
tRNA complement(141018..141089)
/locus_tag="YNCK0005C"
/product="tRNA-Glu"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006558"
gene complement(141794..142819)
/gene="PIR1"
/locus_tag="YKL164C"
/gene_synonym="CCW6"
mRNA complement(141794..142819)
/gene="PIR1"
/locus_tag="YKL164C"
/gene_synonym="CCW6"
/product="beta-1,3-glucan linked protein"
CDS complement(141794..142819)
/gene="PIR1"
/locus_tag="YKL164C"
/gene_synonym="CCW6"
/experiment="EXISTENCE:direct assay:GO:0005199 structural
constituent of cell wall [PMID:9301021]"
/experiment="EXISTENCE:direct assay:GO:0005621 cellular
bud scar [PMID:16278454]"
/experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
cell wall [PMID:15781460|PMID:9192695]"
/experiment="EXISTENCE:direct assay:GO:0034399 nuclear
periphery [PMID:25817432]"
/experiment="EXISTENCE:mutant phenotype:GO:0006886
intracellular protein transport [PMID:11238901]"
/experiment="EXISTENCE:mutant phenotype:GO:0031505
fungal-type cell wall organization [PMID:10407261]"
/note="O-glycosylated protein required for cell wall
stability; attached to the cell wall via beta-1,3-glucan;
mediates mitochondrial translocation of Apn1p; expression
regulated by the cell integrity pathway and by Swi5p
during the cell cycle; PIR1 has a paralog, YJL160C, that
arose from the whole genome duplication"
/codon_start=1
/product="beta-1,3-glucan linked protein"
/protein_id="DAA09001.1"
/db_xref="SGD:S000001647"
/translation="MQYKKSLVASALVATSLAAYAPKDPWSTLTPSATYKGGITDYSS
TFGIAVEPIATTASSKAKRAAAISQIGDGQIQATTKTTAAAVSQIGDGQIQATTKTKA
AAVSQIGDGQIQATTKTTSAKTTAAAVSQIGDGQIQATTKTKAAAVSQIGDGQIQATT
KTTAAAVSQIGDGQIQATTKTTAAAVSQIGDGQIQATTNTTVAPVSQITDGQIQATTL
TSATIIPSPAPAPITNGTDPVTAETCKSSGTLEMNLKGGILTDGKGRIGSIVANRQFQ
FDGPPPQAGAIYAAGWSITPEGNLAIGDQDTFYQCLSGNFYNLYDEHIGTQCNAVHLQ
AIDLLNC"
gene 144401..145378
/gene="PIR3"
/locus_tag="YKL163W"
/gene_synonym="CCW8"
mRNA 144401..145378
/gene="PIR3"
/locus_tag="YKL163W"
/gene_synonym="CCW8"
/product="beta-1,3-glucan linked protein"
CDS 144401..145378
/gene="PIR3"
/locus_tag="YKL163W"
/gene_synonym="CCW8"
/experiment="EXISTENCE:direct assay:GO:0005199 structural
constituent of cell wall [PMID:10407261]"
/experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
cell wall [PMID:15781460|PMID:9192695]"
/experiment="EXISTENCE:mutant phenotype:GO:0031505
fungal-type cell wall organization [PMID:10407261]"
/note="O-glycosylated covalently-bound cell wall protein;
required for cell wall stability; expression is cell cycle
regulated, peaking in M/G1 and also subject to regulation
by the cell integrity pathway; coding sequence contains
length polymorphisms in different strains; PIR3 has a
paralog, HSP150, that arose from the whole genome
duplication"
/codon_start=1
/product="beta-1,3-glucan linked protein"
/protein_id="DAA09002.1"
/db_xref="SGD:S000001646"
/translation="MQYKKPLVVSALAATSLAAYAPKDPWSTLTPSATYKGGITDYSS
SFGIAIEAVATSASSVASSKAKRAASQIGDGQVQAATTTAAVSKKSTAAAVSQITDGQ
VQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAA
KSTAAAASQISDGQVQATTSTKAAASQITDGQIQASKTTSGASQVSDGQVQATAEVKD
ANDPVDVVSCNNNSTLSMSLSKGILTDRKGRIGSIVANRQFQFDGPPPQAGAIYAAGW
SITPEGNLALGDQDTFYQCLSGDFYNLYDKHIGSQCHEVYLQAIDLIDC"
gene complement(147630..148838)
/locus_tag="YKL162C"
mRNA complement(147630..148838)
/locus_tag="YKL162C"
/product="type II protein arginine methyltransferase"
CDS complement(147630..148838)
/locus_tag="YKL162C"
/EC_number="2.1.1.320"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14562095]"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the mitochondrion"
/codon_start=1
/product="type II protein arginine methyltransferase"
/protein_id="DAA09003.1"
/db_xref="SGD:S000001645"
/translation="MMKRLHPLRIQVHLKSDYPLFTFEQLLSTNGIRRGQTARISLKD
YIEWQNFPNIMKRENFFTQRKPVTTTAKEEPFSFDNILDCEPQFSKCLAKWLLVNYKL
NDYPYYDLNIVNIYTDLPQAIQICKNLMSYLKSTLSDNMFQKIKYFMVPLYKCDKIPS
KLLDGIPGSVSLVQDYPVSPYFLQKKFHIEDPIQILMLNDVIKYTTHDLVRYSSDDKG
WQQCFVDINKNGQKSKSFDSAIDYSCELALEQMFNDRSHVSPGKELYIPTKLIEILMT
IKNNIPEHRLFIVDTPQRSSPTIISLLKSLISPRPTGSSQIVQPYSDSIFSDKRSGRI
CFMTDFLQLQNIYNGINSSSSSCEVEDVADFVEKWISPSERSTLSSQNGNRPQLEDIK
NSSLAVLHST"
gene complement(149386..150687)
/gene="KDX1"
/locus_tag="YKL161C"
/gene_synonym="MLP1"
mRNA complement(149386..150687)
/gene="KDX1"
/locus_tag="YKL161C"
/gene_synonym="MLP1"
/product="putative protein kinase KDX1"
CDS complement(149386..150687)
/gene="KDX1"
/locus_tag="YKL161C"
/gene_synonym="MLP1"
/EC_number="2.7.11.1"
/note="Protein kinase; implicated in Slt2p
mitogen-activated (MAP) kinase signaling pathway;
interacts with numerous components in the mating pheromone
and CWI MAPK pathways; associates with Rlm1p; KDX1 has a
paralog, SLT2, that arose from the whole genome
duplication"
/codon_start=1
/product="putative protein kinase KDX1"
/protein_id="DAA09004.1"
/db_xref="SGD:S000001644"
/translation="MATDTERCIFRAFGQDFILNKHFHLTGKIGRGSHSLICSSTYTE
SNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALN
GVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLL
VNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWS
TGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIP
GRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEEFSCQKTF
RFEFEHIESMAELGNEVIKEVFDFRKVVRKHPISGDSPSSSLSLEDAIPQEVVQVHPS
RKVLPSYSPEFSYVSQLPSLTTTQPYQNLMGISSNSFQGVN"
rep_origin 153020..153135
/note="ARS1106; Autonomously Replicating Sequence"
/db_xref="SGD:S000118402"
gene 153269..153706
/gene="ELF1"
/locus_tag="YKL160W"
mRNA 153269..153706
/gene="ELF1"
/locus_tag="YKL160W"
/product="Elf1p"
CDS 153269..153706
/gene="ELF1"
/locus_tag="YKL160W"
/experiment="EXISTENCE:direct assay:GO:0000993 RNA
polymerase II complex binding [PMID:20818391]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095|PMID:19159085]"
/experiment="EXISTENCE:direct assay:GO:0008023
transcription elongation factor complex [PMID:20818391]"
/experiment="EXISTENCE:genetic interaction:GO:0006368
transcription elongation by RNA polymerase II
[PMID:16260625]"
/experiment="EXISTENCE:mutant phenotype:GO:0006368
transcription elongation by RNA polymerase II
[PMID:16260625]"
/experiment="EXISTENCE:mutant phenotype:GO:0045815
transcription initiation-coupled chromatin remodeling
[PMID:16260625]"
/note="Transcription elongation factor with a conserved
zinc finger domain; implicated in the maintenance of
proper chromatin structure in actively transcribed
regions; deletion inhibits Brome mosaic virus (BMV) gene
expression"
/codon_start=1
/product="Elf1p"
/protein_id="DAA09005.1"
/db_xref="SGD:S000001643"
/translation="MGKRKKSTRKPTKRLVQKLDTKFNCLFCNHEKSVSCTLDKKNSI
GTLSCKICGQSFQTRINSLSQPVDVYSDWFDAVEEVNSGRGSDTDDGDEGSDSDYESD
SEQDAKTQNDGEIDSDEEEVDSDEERIGQVKRGRGALVDSDDE"
gene complement(153816..154451)
/gene="RCN1"
/locus_tag="YKL159C"
mRNA complement(153816..154451)
/gene="RCN1"
/locus_tag="YKL159C"
/product="Rcn1p"
CDS complement(153816..154451)
/gene="RCN1"
/locus_tag="YKL159C"
/experiment="EXISTENCE:curator inference:GO:0005737
cytoplasm [PMID:10887154]"
/experiment="EXISTENCE:direct assay:GO:0030346 protein
phosphatase 2B binding [PMID:10887154]"
/experiment="EXISTENCE:mutant phenotype:GO:0008597
calcium-dependent protein serine/threonine phosphatase
regulator activity [PMID:10887154]"
/experiment="EXISTENCE:mutant phenotype:GO:0019722
calcium-mediated signaling [PMID:17954914]"
/note="Protein involved in calcineurin regulation during
calcium signaling; has similarity to H. sapiens DSCR1
which is found in the Down Syndrome candidate region"
/codon_start=1
/product="Rcn1p"
/protein_id="DAA09006.1"
/db_xref="SGD:S000001642"
/translation="MGNIITDTIIITSDKCDIVDNDNVERIQVWLSKNILRKFQINEN
EPLQLIILKRFKRILLICPSHDISQHVMDASRALEMENFNFSYSLQDGQRNLTKQYLK
VPESEKMFLISPPASPPPEFDFSKCEDAPQRHIQSHIQQDQQQRLEASQLLPNNPDKN
NNGTFTLLKSKVGAITIDRCPTNDGNGQMQLADHVKTAFPPKSIFDTDDDD"
gene 154991..158232
/gene="APE2"
/locus_tag="YKL157W"
/gene_synonym="LAP1"
/gene_synonym="YKL158W"
mRNA join(154991..155271,155655..158232)
/gene="APE2"
/locus_tag="YKL157W"
/gene_synonym="LAP1"
/gene_synonym="YKL158W"
/product="metallo-aminopeptidase"
CDS join(154991..155271,155655..158232)
/gene="APE2"
/locus_tag="YKL157W"
/gene_synonym="LAP1"
/gene_synonym="YKL158W"
/experiment="EXISTENCE:direct assay:GO:0005576
extracellular region [PMID:383482]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0030287 cell
wall-bounded periplasmic space [PMID:383482]"
/experiment="EXISTENCE:direct assay:GO:0043171 peptide
catabolic process [PMID:6352682]"
/experiment="EXISTENCE:direct assay:GO:0070006
metalloaminopeptidase activity [PMID:6352682]"
/experiment="EXISTENCE:mutant phenotype:GO:0043171 peptide
catabolic process [PMID:3286257]"
/note="Aminopeptidase yscII; may have role in obtaining
leucine from dipeptide substrates; targeted to vacuole via
Vps10p-dependent endosomal vacuolar protein sorting
pathway; APE2 has a paralog, AAP1, that arose from the
whole genome duplication"
/codon_start=1
/product="metallo-aminopeptidase"
/protein_id="DAA09007.2"
/db_xref="SGD:S000001640"
/translation="MPIVRWLLLKSAVRGSSLIGKAHPCLRSIAAHPRYLSNVYSPPA
GVSRSLRINVMWKQSKLTPPRFVKIMNRRPLFTETSHACAKCQKTSQLLNKTPNREIL
PDNVVPLHYDLTVEPDFKTFKFEGSVKIELKINNPAIDTVTLNTVDTDIHSAKIGDVT
SSEIISEEEQQVTTFAFPKGTMSSFKGNAFLDIKFTGILNDNMAGFYRAKYEDKLTGE
TKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVKNEYVKDGKK
VTLFNTTPKMSTYLVAFIVAELKYVESKNFRIPVRVYATPGNEKHGQFAADLTAKTLA
FFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDLLLDKDNSTLDRIQRVAE
VVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEWKVWEQYVTDTLQH
ALSLDSLRSSHPIEVPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFIKGVSQY
LNKFKYGNAKTEDLWDALADASGKDVRSVMNIWTKKVGFPVISVSEDGNGKITFRQNR
YLSTADVKPDEDKTIYPVFLALKTKNGVDSSVVLSERSKTIELEDPTFFKVNSEQSGI
YITSYTDERWAKLGQQADLLSVEDRVGLVADVKTLSASGYTSTTNFLNLVSKWNNEKS
FVVWDQIINSISSMKSTWLFEPKETQDALDNFTKQLISGMTHHLGWEFKSSDSFSTQR
LKVTMFGAACAARDADVEKAALKMFTDYCSGNKEAIPALIKPIVFNTVARVGGAENYE
KVYKIYLDPISNDEKLAALRSLGRFKEPKLLERTLGYLFDGTVLNQDIYIPMQGMRAH
QEGVEALWNWVKKNWDELVKRLPPGLSMLGSVVTLGTSGFTSMQKIDEIKKFFATKST
KGFDQSLAQSLDTITSKAQWVNRDRDVVNKYLKENGYY"
gene 158613..159212
/gene="RPS27A"
/locus_tag="YKL156W"
mRNA join(158613..158615,158967..159212)
/gene="RPS27A"
/locus_tag="YKL156W"
/product="ribosomal 40S subunit protein S27A"
CDS join(158613..158615,158967..159212)
/gene="RPS27A"
/locus_tag="YKL156W"
/experiment="EXISTENCE:direct assay:GO:0003735 structural
constituent of ribosome [PMID:3533916]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276]"
/experiment="EXISTENCE:direct assay:GO:0022627 cytosolic
small ribosomal subunit [PMID:3533916]"
/experiment="EXISTENCE:genetic interaction:GO:0000462
maturation of SSU-rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]"
/experiment="EXISTENCE:mutant phenotype:GO:0000028
ribosomal small subunit assembly [PMID:9271380]"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S27, no
bacterial homolog; RPS27A has a paralog, RPS27B, that
arose from the whole genome duplication; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="ribosomal 40S subunit protein S27A"
/protein_id="DAA09008.1"
/db_xref="SGD:S000001639"
/translation="MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNIT
TVFSHAQTAVTCESCSTILCTPTGGKAKLSEGTSFRRK"
gene complement(159456..161342)
/gene="RSM22"
/locus_tag="YKL155C"
mRNA complement(159456..161342)
/gene="RSM22"
/locus_tag="YKL155C"
/product="tRNA methyltransferase RSM22"
CDS complement(159456..161342)
/gene="RSM22"
/locus_tag="YKL155C"
/experiment="EXISTENCE:curator inference:GO:0032543
mitochondrial translation [PMID:11278769]"
/experiment="EXISTENCE:direct assay:GO:0003735 structural
constituent of ribosome [PMID:11278769]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005763
mitochondrial small ribosomal subunit [PMID:11278769]"
/note="Mitochondrial ribosomal protein of the small
subunit; also predicted to be an
S-adenosylmethionine-dependent RNA methyltransferase"
/codon_start=1
/product="tRNA methyltransferase RSM22"
/protein_id="DAA09009.1"
/db_xref="SGD:S000001638"
/translation="MMKRCFSILPQNVRFSSKFTSLNLPKLDLADFIDSNKRGINVLP
SYRDETASTTQATNSKELRLLSKTLQGQSYRDQLELNPDVSKAINNNIMAVHIPNNLR
RVATNYYKEIQEPNSLHRPCRTKMEVDAHIASIFLQNYGSIFQSLKELQKRVGPDNFK
PQRILDVGYGPATGIVALNDILGPNYRPDLKDAVILGNAEMQERAKIILSRQLNEVVD
TVEENVSTEKEQETDRRNKNFQEDEHIGEVMTKKINIMTNLRSSIPASKEYDLIILTH
QLLHDGNQFPIQVDENIEHYLNILAPGGHIVIIERGNPMGFEIIARARQITLRPENFP
DEFGKIPRPWSRGVTVRGKKDAELGNISSNYFLKVIAPCPHQRKCPLQVGNPNFYTHK
EGKDLKFCNFQKSIKRPKFSIELKKGKLLATSWDGSQGNASRLKGTGRRNGRDYEILN
YSYLIFERSHKDENTLKEIKKLRNENVNGKYDIGSLGDDTQNSWPRIINDPVKRKGHV
MMDLCAPSGELEKWTVSRSFSKQIYHDARKSKKGDLWASAAKTQIKGLGDLNVKKFHK
LEKERIKQLKKEERQKARKAMESYNELEDSLQFDDHQFSNFEVMKKLSTFHGNDFLQH
VNRK"
gene 161601..162335
/gene="SRP102"
/locus_tag="YKL154W"
mRNA 161601..162335
/gene="SRP102"
/locus_tag="YKL154W"
/product="Signal recognition particle receptor subunit
beta"
CDS 161601..162335
/gene="SRP102"
/locus_tag="YKL154W"
/experiment="EXISTENCE:direct assay:GO:0005789 endoplasmic
reticulum membrane [PMID:9679135]"
/experiment="EXISTENCE:mutant phenotype:GO:0005047 signal
recognition particle binding [PMID:9679135]"
/experiment="EXISTENCE:mutant phenotype:GO:0045047 protein
targeting to ER [PMID:9679135]"
/experiment="EXISTENCE:physical interaction:GO:0005785
signal recognition particle receptor complex
[PMID:9679135]"
/note="Signal recognition particle (SRP) receptor beta
subunit; involved in SRP-dependent protein targeting;
anchors the alpha subunit, Srp101p to the ER membrane"
/codon_start=1
/product="Signal recognition particle receptor subunit
beta"
/protein_id="DAA09010.1"
/db_xref="SGD:S000001637"
/translation="MLSNTLIIACLLVIGTTIALIAVQKASSKTGIKQKSYQPSIIIA
GPQNSGKTSLLTLLTTDSVRPTVVSQEPLSAADYDGSGVTLVDFPGHVKLRYKLSDYL
KTRAKFVKGLIFMVDSTVDPKKLTTTAEFLVDILSITESSCENGIDILIACNKSELFT
ARPPSKIKDALESEIQKVIERRKKSLNEVERKINEEDYAENTLDVLQSTDGFKFANLE
ASVVAFEGSINKRKISQWREWIDEKL"
gene complement(162487..162558)
/locus_tag="YNCK0006C"
tRNA complement(162487..162558)
/locus_tag="YNCK0006C"
/product="tRNA-Arg"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon UCU (converted to mcm5-UCU in the mature
tRNA), decodes AGA codons into arginine, one of 19 nuclear
tRNAs for arginine"
/db_xref="SGD:S000006716"
repeat_region 162831..163169
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007056"
gene complement(163642..164385)
/gene="GPM1"
/locus_tag="YKL152C"
mRNA complement(163642..164385)
/gene="GPM1"
/locus_tag="YKL152C"
/product="phosphoglycerate mutase GPM1"
CDS complement(163642..164385)
/gene="GPM1"
/locus_tag="YKL152C"
/EC_number="5.4.2.11"
/experiment="EXISTENCE:direct assay:GO:0004619
phosphoglycerate mutase activity [PMID:1386023]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:16962558|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005758
mitochondrial intermembrane space [PMID:22984289]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:3332961]"
/experiment="EXISTENCE:mutant phenotype:GO:0004619
phosphoglycerate mutase activity [PMID:3033435]"
/experiment="EXISTENCE:mutant phenotype:GO:0006094
gluconeogenesis [PMID:3033435]"
/experiment="EXISTENCE:mutant phenotype:GO:0006096
glycolytic process [PMID:11015729]"
/note="Tetrameric phosphoglycerate mutase; mediates the
conversion of 3-phosphoglycerate to 2-phosphoglycerate
during glycolysis and the reverse reaction during
gluconeogenesis"
/codon_start=1
/product="phosphoglycerate mutase GPM1"
/protein_id="DAA09011.1"
/db_xref="SGD:S000001635"
/translation="MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLK
EKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETL
KKFGEEKFNTYRRSFDVPPPPIDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLL
PYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDADIAKLNIPTGIPLVFELDE
NLKPSKPSYYLDPEAAAAGAAAVANQGKK"
gene complement(164917..165930)
/gene="NNR2"
/locus_tag="YKL151C"
mRNA complement(164917..165930)
/gene="NNR2"
/locus_tag="YKL151C"
/product="NADHX dehydratase"
CDS complement(164917..165930)
/gene="NNR2"
/locus_tag="YKL151C"
/EC_number="4.2.1.93"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0046496
nicotinamide nucleotide metabolic process [PMID:21994945]"
/experiment="EXISTENCE:direct assay:GO:0047453
ATP-dependent NAD(P)H-hydrate dehydratase activity
[PMID:21994945]"
/note="Widely-conserved NADHX dehydratase; converts
(S)-NADHX to NADH in ATP-dependent manner; YKL151C
promoter contains STREs (stress response elements) and
expression is induced by heat shock or methyl
methanesulfonate; downstream intergenic region drives
antisense expression and mediates coordinated regulation
of YKL151C and GPM1 phosphoglycerate mutase; protein
abundance increases in response to DNA replication stress;
homolog of Carkd in mammals and C-terminus of YjeF in
E.coli"
/codon_start=1
/product="NADHX dehydratase"
/protein_id="DAA09012.1"
/db_xref="SGD:S000001634"
/translation="MLAELSHRELIKLAQKRCIPPLLPKFHKGQSGGRVCIIGGCEDY
TGAPYFSANATALMGCDLTHVICEYNAGTVIKSYTPNLMVHPYLRMSNTKLDVDMDEQ
RKKINSLLDRIHVVVIGPGLGRDPLMLKSIKDIIRYILEKHEGKIPLVIDADGLFLVT
QDSEVKEMLKSYPKGRVILTPNVVEFKRLCDAIGKKGDSHSEMGSLIAQELNCIVVEK
GQSDKIFSPDSEKDMLTNSEEGSNKRVGGQGDTLTGAISCMLAFSRAMYDFKICEQEE
KGESSNDKPLKNWVDYAMLSCYAGCTITRECSRLGFKAKGRAMQTTDLNDRVGEVFAK
LFG"
gene 166544..167452
/gene="MCR1"
/locus_tag="YKL150W"
mRNA 166544..167452
/gene="MCR1"
/locus_tag="YKL150W"
/product="cytochrome-b5 reductase"
CDS 166544..167452
/gene="MCR1"
/locus_tag="YKL150W"
/EC_number="1.6.2.2"
/experiment="EXISTENCE:direct assay:GO:0004128
cytochrome-b5 reductase activity, acting on NAD(P)H
[PMID:8001120]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005741
mitochondrial outer membrane
[PMID:16407407|PMID:16689936|PMID:8001120]"
/experiment="EXISTENCE:direct assay:GO:0005758
mitochondrial intermembrane space [PMID:8001120]"
/experiment="EXISTENCE:direct assay:GO:0006696 ergosterol
biosynthetic process [PMID:10622712]"
/experiment="EXISTENCE:mutant phenotype:GO:0034599
cellular response to oxidative stress [PMID:11420140]"
/note="Mitochondrial NADH-cytochrome b5 reductase;
involved in ergosterol biosynthesis"
/codon_start=1
/product="cytochrome-b5 reductase"
/protein_id="DAA09013.1"
/db_xref="SGD:S000001633"
/translation="MFSRLSRSHSKALPIALGTVAIAAATAFYFANRNQHSFVFNESN
KVFKGDDKWIDLPISKIEEESHDTRRFTFKLPTEDSEMGLVLASALFAKFVTPKGSNV
VRPYTPVSDLSQKGHFQLVVKHYEGGKMTSHLFGLKPNDTVSFKGPIMKWKWQPNQFK
SITLLGAGTGINPLYQLAHHIVENPNDKTKVNLLYGNKTPQDILLRKELDALKEKYPD
KFNVTYFVDDKQDDQDFDGEISFISKDFIQEHVPGPKESTHLFVCGPPPFMNAYSGEK
KSPKDQGELIGILNNLGYSKDQVFKF"
gene complement(167612..168829)
/gene="DBR1"
/locus_tag="YKL149C"
/gene_synonym="PRP26"
mRNA complement(167612..168829)
/gene="DBR1"
/locus_tag="YKL149C"
/gene_synonym="PRP26"
/product="RNA lariat debranching enzyme"
CDS complement(167612..168829)
/gene="DBR1"
/locus_tag="YKL149C"
/gene_synonym="PRP26"
/experiment="EXISTENCE:curator inference:GO:0005634
nucleus [PMID:1850323]"
/experiment="EXISTENCE:direct assay:GO:0006401 RNA
catabolic process [PMID:1850323]"
/experiment="EXISTENCE:direct assay:GO:0008419 RNA lariat
debranching enzyme activity [PMID:1850323]"
/experiment="EXISTENCE:mutant phenotype:GO:0000398 mRNA
splicing, via spliceosome [PMID:24919400]"
/experiment="EXISTENCE:mutant phenotype:GO:0006401 RNA
catabolic process [PMID:1850323]"
/experiment="EXISTENCE:mutant phenotype:GO:0007124
pseudohyphal growth [PMID:9055077]"
/experiment="EXISTENCE:mutant phenotype:GO:0008419 RNA
lariat debranching enzyme activity [PMID:1850323]"
/experiment="EXISTENCE:mutant phenotype:GO:0016074
sno(s)RNA metabolic process [PMID:9740128]"
/experiment="EXISTENCE:mutant phenotype:GO:0032197
retrotransposition [PMID:10652222]"
/note="RNA lariat debranching enzyme; catalyzes
debranching of lariat introns formed during pre-mRNA
splicing; required for efficient Ty1 transposition;
knockdown of human homolog Dbr1 rescues toxicity of
RNA-binding proteins TDP-43 and FUS which are implicated
in amyotrophic lateral sclerosis (ALS), suggests potential
therapeutic target for ALS and related TDP-43
proteinopathies; human homolog DBR1 can complement yeast
dbr1 null mutant"
/codon_start=1
/product="RNA lariat debranching enzyme"
/protein_id="DAA09014.1"
/db_xref="SGD:S000001632"
/translation="MTKLRIAVQGCCHGQLNQIYKEVSRIHAKTPIDLLIILGDFQSI
RDGQDFKSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGYVA
KNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKANIRNLYHVRI
SDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPFFEQDIKEGKLGSPVTWQL
LRDLRPQWWLSAHLHVRFMASIKHNKRSHEPPNKSTSKTKKNNNEIDLDLSSDEDERS
GIMNCQEENEYDSKYGETRFLALDKCLPRRRWLEILEIEPDTSHASWKDENHRMFWDP
EFINNLVICQKNKNLLSNKPFNSVNWIELSQSNREEGRDIDWENYAIPAYTLDIQKDE
VRQTKAFISKFMT"
gene complement(169207..171129)
/gene="SDH1"
/locus_tag="YKL148C"
mRNA complement(169207..171129)
/gene="SDH1"
/locus_tag="YKL148C"
/product="succinate dehydrogenase flavoprotein subunit
SDH1"
CDS complement(169207..171129)
/gene="SDH1"
/locus_tag="YKL148C"
/EC_number="1.3.5.1"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239|PMID:2826438]"
/experiment="EXISTENCE:direct assay:GO:0005749
mitochondrial respiratory chain complex II, succinate
dehydrogenase complex (ubiquinone) [PMID:9822678]"
/experiment="EXISTENCE:direct assay:GO:0006121
mitochondrial electron transport, succinate to ubiquinone
[PMID:2826438]"
/experiment="EXISTENCE:direct assay:GO:0008177 succinate
dehydrogenase (ubiquinone) activity [PMID:13445213]"
/experiment="EXISTENCE:direct assay:GO:0031966
mitochondrial membrane [PMID:1939170]"
/experiment="EXISTENCE:direct assay:GO:0050660 flavin
adenine dinucleotide binding [PMID:18279395]"
/experiment="EXISTENCE:genetic interaction:GO:0008177
succinate dehydrogenase (ubiquinone) activity
[PMID:16232921]"
/experiment="EXISTENCE:genetic interaction:GO:0045333
cellular respiration [PMID:16232921|PMID:9730279]"
/experiment="EXISTENCE:mutant phenotype:GO:0008177
succinate dehydrogenase (ubiquinone) activity
[PMID:16232921|PMID:197391|PMID:9730279]"
/experiment="EXISTENCE:mutant phenotype:GO:0045333
cellular respiration [PMID:16232921|PMID:9730279]"
/experiment="EXISTENCE:mutant phenotype:GO:0050660 flavin
adenine dinucleotide binding [PMID:1939170]"
/note="Flavoprotein subunit of succinate dehydrogenase;
couples the oxidation of succinate to the transfer of
electrons to ubiquinone as part of the TCA cycle and the
mitochondrial respiratory chain; FAD binding to Sdh1p is
required for the assembly of the succinate dehydrogenase
subunits; mutations in human ortholog SDHA are associated
with Leigh syndrome and predisposition to several cancers"
/codon_start=1
/product="succinate dehydrogenase flavoprotein subunit
SDH1"
/protein_id="DAA09015.1"
/db_xref="SGD:S000001631"
/translation="MLSLKKSALSKLTLLRNTRTFTSSALVRQTQGSVNGSASRSADG
KYHIIDHEYDCVVIGAGGAGLRAAFGLAEAGYKTACISKLFPTRSHTVAAQGGINAAL
GNMHKDNWKWHMYDTVKGSDWLGDQDSIHYMTREAPKSIIELEHYGVPFSRTENGKIY
QRAFGGQTKEYGKGAQAYRTCAVADRTGHALLHTLYGQALRHDTHFFIEYFALDLLTH
NGEVVGVIAYNQEDGTIHRFRAHKTIIATGGYGRAYFSCTSAHTCTGDGNAMVSRAGF
PLQDLEFVQFHPSGIYGSGCLITEGARGEGGFLVNSEGERFMERYAPTAKDLACRDVV
SRAITMEIREGRGVGKKKDHMYLQLSHLPPEVLKERLPGISETAAIFAGVDVTKEPIP
IIPTVHYNMGGIPTKWNGEALTIDEETGEDKVIPGLMACGEAACVSVHGANRLGANSL
LDLVVFGRAVAHTVADTLQPGLPHKPLPSDLGKESIANLDKLRNANGSRSTAEIRMNM
KQTMQKDVSVFRTQSSLDEGVRNITAVEKTFDDVKTTDRSMIWNSDLVETLELQNLLT
CASQTAVSAANRKESRGAHAREDYPNRDDEHWMKHTLSWQKDVAAPVTLKYRRVIDHT
LDEKECPSVPPTVRAY"
gene 171783..173861
/gene="AVT3"
/locus_tag="YKL146W"
mRNA 171783..173861
/gene="AVT3"
/locus_tag="YKL146W"
/product="Avt3p"
CDS 171783..173861
/gene="AVT3"
/locus_tag="YKL146W"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:27246536]"
/experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
vacuole membrane [PMID:26928762]"
/experiment="EXISTENCE:genetic interaction:GO:0005302
L-tyrosine transmembrane transporter activity
[PMID:11274162]"
/experiment="EXISTENCE:genetic interaction:GO:0015186
L-glutamine transmembrane transporter activity
[PMID:11274162]"
/experiment="EXISTENCE:genetic interaction:GO:0015188
L-isoleucine transmembrane transporter activity
[PMID:11274162]"
/experiment="EXISTENCE:genetic interaction:GO:0032974
amino acid transmembrane export from vacuole
[PMID:11274162]"
/experiment="EXISTENCE:mutant phenotype:GO:0000329
fungal-type vacuole membrane [PMID:11274162]"
/experiment="EXISTENCE:mutant phenotype:GO:0005302
L-tyrosine transmembrane transporter activity
[PMID:11274162]"
/experiment="EXISTENCE:mutant phenotype:GO:0015186
L-glutamine transmembrane transporter activity
[PMID:11274162]"
/experiment="EXISTENCE:mutant phenotype:GO:0015188
L-isoleucine transmembrane transporter activity
[PMID:11274162]"
/experiment="EXISTENCE:mutant phenotype:GO:0015824 proline
transport [PMID:27246536]"
/experiment="EXISTENCE:mutant phenotype:GO:0032974 amino
acid transmembrane export from vacuole [PMID:11274162]"
/note="Vacuolar transporter; exports large neutral amino
acids from vacuole; targeted to vacuole via AP-3 pathway;
member of family of seven S. cerevisiae genes (AVT1-7)
related to vesicular GABA-glycine transporters"
/codon_start=1
/product="Avt3p"
/protein_id="DAA09016.1"
/db_xref="SGD:S000001629"
/translation="MNGKEVSSGSGRTQSNNNKKNNNGGSTGISHASGSPLTDGNGGN
SNGNSRSRSRSRKSSGTTGGLLKKPPLLVNNEAVHASVPDASHTSCNNGTLEVSINNP
EPHVVDAVARHLIRNPSNSLQLQGGDITRDLYKWTNDHPSSPSQYQYPSQPALSTSIP
SQAPSFSNRKRSMSFSAASIASSSHLNNNSEANGNPLAAIGLAPAPMTHEEIRAPGGF
RRSFIIQKRRKHNVDAPIPNFFTRNFIEFLTLYGHFAGEDLSEEEEEEEETEEEPEEE
ALETESTQLVSREHGRHPHKSSTVKAVLLLLKSFVGTGVLFLPKAFHNGGWGFSALCL
LSCALISYGCFVSLITTKDKVGVDGYGDMGRILYGPKMKFAILSSIALSQIGFSAAYT
VFTATNLQVFSENFFHLKPGSISLATYIFAQVLIFVPLSLTRNIAKLSGTALIADLFI
LLGLVYVYVYSIYYIAVNGVASDTMLMFNKADWSLFIGTAIFTFEGIGLLIPIQESMK
HPKHFRPSLSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLNFPQDTSYTLTVQLLYA
LAILLSTPLQLFPAIRILENWTFPSNASGKYNPKVKWLKNYFRCAIVVLTSILAWVGA
NDLDKFVSLVGSFACIPLIYIYPPLLHYKASILSGTSRARLLLDLIVIVFGVAVMAYT
SWQTIKMWSQ"
gene 174213..175616
/gene="RPT1"
/locus_tag="YKL145W"
/gene_synonym="CIM5"
/gene_synonym="YTA3"
mRNA 174213..175616
/gene="RPT1"
/locus_tag="YKL145W"
/gene_synonym="CIM5"
/gene_synonym="YTA3"
/product="proteasome regulatory particle base subunit
RPT1"
CDS 174213..175616
/gene="RPT1"
/locus_tag="YKL145W"
/gene_synonym="CIM5"
/gene_synonym="YTA3"
/experiment="EXISTENCE:direct assay:GO:0008540 proteasome
regulatory particle, base subcomplex [PMID:9741626]"
/experiment="EXISTENCE:direct assay:GO:0045732 positive
regulation of protein catabolic process [PMID:15135049]"
/experiment="EXISTENCE:mutant phenotype:GO:0045899
positive regulation of RNA polymerase II transcription
preinitiation complex assembly [PMID:19843524]"
/experiment="EXISTENCE:mutant phenotype:GO:0070682
proteasome regulatory particle assembly [PMID:19412160]"
/experiment="EXISTENCE:physical interaction:GO:0006511
ubiquitin-dependent protein catabolic process
[PMID:15135049]"
/experiment="EXISTENCE:physical interaction:GO:0031625
ubiquitin protein ligase binding [PMID:10688918]"
/note="ATPase of the 19S regulatory particle of the 26S
proteasome; one of six ATPases of the regulatory particle;
involved in the degradation of ubiquitinated substrates;
required for optimal CDC20 transcription; interacts with
Rpn12p and Ubr1p; mutant has aneuploidy tolerance"
/codon_start=1
/product="proteasome regulatory particle base subunit
RPT1"
/protein_id="DAA09017.1"
/db_xref="SGD:S000001628"
/translation="MPPKEDWEKYKAPLEDDDKKPDDDKIVPLTEGDIQVLKSYGAAP
YAAKLKQTENDLKDIEARIKEKAGVKESDTGLAPSHLWDIMGDRQRLGEEHPLQVARC
TKIIKGNGESDETTTDNNNSGNSNSNSNQQSTDADEDDEDAKYVINLKQIAKFVVGLG
ERVSPTDIEEGMRVGVDRSKYNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQI
EKLREVVELPLLSPERFATLGIDPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIG
SELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFDDGAGGDNEVQRTML
ELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVEFSLPDLEGRANIFRIH
SKSMSVERGIRWELISRLCPNSTGAELRSVCTEAGMFAIRARRKVATEKDFLKAVDKV
ISGYKKFSSTSRYMQYN"
gene complement(175843..176481)
/gene="RPC25"
/locus_tag="YKL144C"
/gene_synonym="YKL1"
mRNA complement(175843..176481)
/gene="RPC25"
/locus_tag="YKL144C"
/gene_synonym="YKL1"
/product="DNA-directed RNA polymerase III subunit RPC25"
CDS complement(175843..176481)
/gene="RPC25"
/locus_tag="YKL144C"
/gene_synonym="YKL1"
/experiment="EXISTENCE:direct assay:GO:0001056 RNA
polymerase III activity [PMID:3905793]"
/experiment="EXISTENCE:direct assay:GO:0005666 RNA
polymerase III complex [PMID:10611227|PMID:3905793]"
/experiment="EXISTENCE:direct assay:GO:0042797 tRNA
transcription by RNA polymerase III [PMID:3905793]"
/experiment="EXISTENCE:mutant phenotype:GO:0006384
transcription initiation at RNA polymerase III promoter
[PMID:15612920]"
/experiment="EXISTENCE:mutant phenotype:GO:0042797 tRNA
transcription by RNA polymerase III
[PMID:15612920|PMID:8065349]"
/note="RNA polymerase III subunit C25; required for
transcription initiation; forms a heterodimer with Rpc17p;
paralog of Rpb7p"
/codon_start=1
/product="DNA-directed RNA polymerase III subunit RPC25"
/protein_id="DAA09018.1"
/db_xref="SGD:S000001627"
/translation="MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGL
CITIYDLLTVEEGQLKPGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLL
GIFDDIFIPQNMLFEGCYYTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVFVDVKP
KSPKERELEERAQLENEIEGKNEETPQNEKPPAYALLGSCQTDGMGLVSWWE"
gene 176781..178172
/gene="LTV1"
/locus_tag="YKL143W"
/gene_synonym="YKL2"
mRNA 176781..178172
/gene="LTV1"
/locus_tag="YKL143W"
/gene_synonym="YKL2"
/product="Ltv1p"
CDS 176781..178172
/gene="LTV1"
/locus_tag="YKL143W"
/gene_synonym="YKL2"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:16888326]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095|PMID:16888326]"
/experiment="EXISTENCE:direct assay:GO:0030688
preribosome, small subunit precursor
[PMID:16738661|PMID:15167894]"
/experiment="EXISTENCE:direct assay:GO:0031902 late
endosome membrane [PMID:16732272]"
/experiment="EXISTENCE:direct assay:GO:0071986 Ragulator
complex [PMID:16732272]"
/experiment="EXISTENCE:genetic interaction:GO:0000056
ribosomal small subunit export from nucleus
[PMID:16888326]"
/experiment="EXISTENCE:mutant phenotype:GO:0000056
ribosomal small subunit export from nucleus
[PMID:16888326]"
/experiment="EXISTENCE:mutant phenotype:GO:0006970
response to osmotic stress [PMID:15611164]"
/experiment="EXISTENCE:mutant phenotype:GO:0034599
cellular response to oxidative stress [PMID:15611164]"
/experiment="EXISTENCE:mutant phenotype:GO:0042274
ribosomal small subunit biogenesis [PMID:15611164]"
/experiment="EXISTENCE:mutant phenotype:GO:1904669 ATP
export [PMID:26585826]"
/note="Subunit of the EGO/GSE complex; the
vacuolar/endosomal membrane associated EGO/GSE complex
regulates exit from rapamycin-induced growth arrest,
stimulating microautophagy and sorting of Gap1p from the
endosome to the plasma membrane; required for ribosomal
small subunit export from nucleus; required for growth at
low temperature"
/codon_start=1
/product="Ltv1p"
/protein_id="DAA09019.1"
/db_xref="SGD:S000001626"
/translation="MSKKFSSKNSQRYVVVHRPHDDPSFYDTDASAHVLVPVSNPNKT
SPEADLRKKDVSSTKPKGRRAHVGEAALYGINFDDSEYDYTQHLKPIGLDPENSIFIA
SKGNEQKVEKKNIEDLFIEPKYRRDEIEKDDALPVFQRGMAKPEYLLHQQDTTDEIRG
FKPDMNPALREVLEALEDEAYVVNDDVVVEDISKKTQLQGDNYGEEEKEDDIFAQLLG
SGEAKDEDEFEDEFDEWDIDNVENFEDENYVKEMAQFDNIENLEDLENIDYQADVRRF
QKDNSILEKHNSDDEFSNAGLDSVNPSEEEDVLGELPSIQDKSKTGKKKRKSRQKKGA
MSDVSGFSMSSSAIARTETMTVLDDQYDQIINGYENYEEELEEDEEQNYQPFDMSAER
SDFESMLDDFLDNYELESGGRKLAKKDKEIERLKEAADEVSKGKLSQRRNRERQEKKK
LEKVTNTLSSLKF"
gene 178515..179174
/gene="MRP8"
/locus_tag="YKL142W"
/gene_synonym="YKL3"
mRNA 178515..179174
/gene="MRP8"
/locus_tag="YKL142W"
/gene_synonym="YKL3"
/product="Mrp8p"
CDS 178515..179174
/gene="MRP8"
/locus_tag="YKL142W"
/gene_synonym="YKL3"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/note="hypothetical protein; undergoes sumoylation;
transcription induced under cell wall stress; protein
levels are reduced under anaerobic conditions; protein
abundance increases in response to DNA replication stress;
originally thought to be a mitochondrial ribosomal protein
based on sequence analysis"
/codon_start=1
/product="Mrp8p"
/protein_id="DAA09020.1"
/db_xref="SGD:S000001625"
/translation="MSNEIELLQKQVSELQDLVKKQSLIISKTGERVLELQLDKQKHD
VTDFDSKFSKSISKKSGSATQFDATDFATNEDLVELVKELQGELNFIEERSIRRLVNS
LKKDDDDVIAPLPNADGDIPAISDGVFPKSLKEFKDIPDLKLVRLAKFYERLPPTLKE
QEDFENFLEGKVEAFHINETTDEEISKELEKFSKDELDDAFNDVARYLGLSLRRGTEI
W"
gene 179667..180263
/gene="SDH3"
/locus_tag="YKL141W"
/gene_synonym="CYB3"
/gene_synonym="YKL4"
mRNA 179667..180263
/gene="SDH3"
/locus_tag="YKL141W"
/gene_synonym="CYB3"
/gene_synonym="YKL4"
/product="succinate dehydrogenase cytochrome b subunit
SDH3"
CDS 179667..180263
/gene="SDH3"
/locus_tag="YKL141W"
/gene_synonym="CYB3"
/gene_synonym="YKL4"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005749
mitochondrial respiratory chain complex II, succinate
dehydrogenase complex (ubiquinone)
[PMID:22152483|PMID:9822678]"
/experiment="EXISTENCE:direct assay:GO:0042721 TIM22
mitochondrial import inner membrane insertion complex
[PMID:22152483]"
/experiment="EXISTENCE:genetic interaction:GO:0008177
succinate dehydrogenase (ubiquinone) activity
[PMID:18028869]"
/experiment="EXISTENCE:mutant phenotype:GO:0045039 protein
insertion into mitochondrial inner membrane
[PMID:22152483]"
/experiment="EXISTENCE:mutant phenotype:GO:0045333
cellular respiration [PMID:16232921]"
/note="Subunit of succinate dehydrogenase and of TIM22
translocase; functions as cytochrome b subunit of
succinate dehydrogenase, which couples oxidation of
succinate to transfer of electrons to ubiquinone as part
of the TCA cycle and the mitochondrial respiratory chain;
also required for mitochondrial inner membrane protein
import as part of the TIM22 complex; SDH3 has a paralog,
SHH3, that arose from the whole genome duplication"
/codon_start=1
/product="succinate dehydrogenase cytochrome b subunit
SDH3"
/protein_id="DAA09021.1"
/db_xref="SGD:S000001624"
/translation="MSAMMVKLGLNKSALLLKPSAFSRAAALSSSRRLLFNTARTNFL
STSPLKNVASEMNTKAAIAEEQILNKQRAKRPISPHLTIYQPQLTWYLSSLHRISLVL
MGLGFYLFTILFGVSGLLGLGLTTEKVSNWYHQKFSKITEWSIKGSFAYLFAIHYGGA
IRHLIWDTAKELTLKGVYRTGYALIGFTAVLGTYLLTL"
gene 180779..182425
/gene="TGL1"
/locus_tag="YKL140W"
/gene_synonym="YKL5"
mRNA 180779..182425
/gene="TGL1"
/locus_tag="YKL140W"
/gene_synonym="YKL5"
/product="sterol esterase"
CDS 180779..182425
/gene="TGL1"
/locus_tag="YKL140W"
/gene_synonym="YKL5"
/EC_number="3.1.1.13"
/experiment="EXISTENCE:direct assay:GO:0004771 sterol
esterase activity [PMID:15713625]"
/experiment="EXISTENCE:direct assay:GO:0005811 lipid
droplet [PMID:10515935|PMID:15713625|PMID:24868093]"
/experiment="EXISTENCE:direct assay:GO:0016020 membrane
[PMID:15713625]"
/experiment="EXISTENCE:mutant phenotype:GO:0016125 sterol
metabolic process [PMID:15713625]"
/experiment="EXISTENCE:mutant phenotype:GO:0044255
cellular lipid metabolic process [PMID:10515935]"
/note="Steryl ester hydrolase; one of three gene products
(Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester
hydrolase activity and involved in sterol homeostasis;
localized to lipid particle membranes"
/codon_start=1
/product="sterol esterase"
/protein_id="DAA09022.1"
/db_xref="SGD:S000001623"
/translation="MYFPFLGRLSITDYIIVVLVYIESIISSVLKLIPQPMINLFEWL
INFSTSSDDNTIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNR
FNNKVVYLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKP
PKSNKFWDFSIDEFAFFDIPNSIEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLN
RKVSHFIAIAPAMTPKGLHNRIVDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTLHPTL
FNLCIDIANKILFNWKSFNILPRQKIASYAKLYSTTSVKSIVHWFQILRSQKFQMFEE
SDNMLNSLTRPYQIANFPTRTNIKIPILLIYGGIDSLVDIDVMKKNLPFNSVFDVKVD
NYEHLDLIWGKDADTLVIAKVLRFIEFFNPGNVSVKTNQLLPSASLVEELPSTTWKTT
HPTHGLSYRTHSADRSPLSVQADEADEVHNADNSRFLRRVFSTSAIDEDNENEHQDDT
EDQIHKEQQRRLSAYLESSKDLRQLDANSSTTALDALNKE"
gene 182958..184544
/gene="CTK1"
/locus_tag="YKL139W"
mRNA 182958..184544
/gene="CTK1"
/locus_tag="YKL139W"
/product="cyclin-dependent serine/threonine protein kinase
CTK1"
CDS 182958..184544
/gene="CTK1"
/locus_tag="YKL139W"
/EC_number="2.7.11.23"
/experiment="EXISTENCE:direct assay:GO:0004672 protein
kinase activity [PMID:16319894]"
/experiment="EXISTENCE:direct assay:GO:0004693
cyclin-dependent protein serine/threonine kinase activity
[PMID:7565723]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:9110987]"
/experiment="EXISTENCE:direct assay:GO:0005654 nucleoplasm
[PMID:15520468]"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:15520468]"
/experiment="EXISTENCE:direct assay:GO:0032786 positive
regulation of DNA-templated transcription, elongation
[PMID:9110987]"
/experiment="EXISTENCE:direct assay:GO:0070692 CTDK-1
complex [PMID:7565723]"
/experiment="EXISTENCE:genetic interaction:GO:0031124 mRNA
3'-end processing [PMID:12504017]"
/experiment="EXISTENCE:mutant phenotype:GO:0006413
translational initiation [PMID:25416238]"
/experiment="EXISTENCE:mutant phenotype:GO:0031124 mRNA
3'-end processing [PMID:12504017]"
/experiment="EXISTENCE:mutant phenotype:GO:0045903
positive regulation of translational fidelity
[PMID:17545469]"
/experiment="EXISTENCE:mutant phenotype:GO:0045943
positive regulation of transcription by RNA polymerase I
[PMID:15520468]"
/note="Catalytic (alpha) subunit of C-terminal domain
kinase I (CTDK-I); phosphorylates both RNA pol II subunit
Rpo21p to affect transcription and pre-mRNA 3' end
processing, and ribosomal protein Rps2p to increase
translational fidelity; required for H3K36 trimethylation
but not dimethylation by Set2p; suggested stimulatory role
in 80S formation during translation initiation; similar to
the Drosophila dCDK12 and human CDK12 and probably CDK13"
/codon_start=1
/product="cyclin-dependent serine/threonine protein kinase
CTK1"
/protein_id="DAA09023.1"
/db_xref="SGD:S000001622"
/translation="MSYNNGNTYSKSYSRNNKRPLFGKRSPNPQSLARPPPPKRIRTD
SGYQSNMDNISSHRVNSNDQPGHTKSRGNNNLSRYNDTSFQTSSRYQGSRYNNNNTSY
ENRPKSIKRDETKAEFLSHLPKGPKSVEKSRYNNSSNTSNDIKNGYHASKYYNHKGQE
GRSVIAKKVPVSVLTQQRSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQG
EREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEV
QISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSR
ADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIES
IFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLL
CYDQTKRFSATEALQSDYFKEEPKPEPLVLDGLVSCHEYEVKLARKQKRPNILSTNTN
NKGNGNSNNNNNNNNDDDDK"
gene complement(184803..185012)
/gene="HSK3"
/locus_tag="YKL138C-A"
mRNA complement(184803..185012)
/gene="HSK3"
/locus_tag="YKL138C-A"
/product="Hsk3p"
CDS complement(184803..185012)
/gene="HSK3"
/locus_tag="YKL138C-A"
/experiment="EXISTENCE:direct assay:GO:0008017 microtubule
binding [PMID:15664196|PMID:16777964]"
/experiment="EXISTENCE:direct assay:GO:0008608 attachment
of spindle microtubules to kinetochore [PMID:17620411]"
/experiment="EXISTENCE:direct assay:GO:0031116 positive
regulation of microtubule polymerization [PMID:15664196]"
/experiment="EXISTENCE:direct assay:GO:0042729 DASH
complex [PMID:15640796|PMID:15664196]"
/experiment="EXISTENCE:direct assay:GO:0051010 microtubule
plus-end binding [PMID:17620411|PMID:20479465]"
/experiment="EXISTENCE:direct assay:GO:0051987 positive
regulation of attachment of spindle microtubules to
kinetochore [PMID:20479465|PMID:20479468]"
/note="Essential subunit of the Dam1 complex (aka DASH
complex); complex couples kinetochores to the force
produced by MT depolymerization thereby aiding in
chromosome segregation; is transferred to the kinetochore
prior to mitosis"
/codon_start=1
/product="Hsk3p"
/protein_id="DAA09024.1"
/db_xref="SGD:S000028421"
/translation="MNANKQRQYNQLAHELRELQTNLQETTKQLDIMSKQCNENLVGQ
LGKVHGSWLIGSYIYYMEQMLGKTQ"
gene complement(185286..185681)
/gene="MRPL31"
/locus_tag="YKL138C"
/gene_synonym="mL60"
mRNA complement(185286..185681)
/gene="MRPL31"
/locus_tag="YKL138C"
/gene_synonym="mL60"
/product="mitochondrial 54S ribosomal protein YmL31"
CDS complement(185286..185681)
/gene="MRPL31"
/locus_tag="YKL138C"
/gene_synonym="mL60"
/experiment="EXISTENCE:curator inference:GO:0032543
mitochondrial translation [PMID:12392552]"
/experiment="EXISTENCE:direct assay:GO:0003735 structural
constituent of ribosome [PMID:12392552]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005762
mitochondrial large ribosomal subunit [PMID:12392552]"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL31"
/protein_id="DAA09025.1"
/db_xref="SGD:S000001621"
/translation="MFGPFKLTSPVAGGLLWKIPWRMSTHQKTRQRERLRNVDQVIKQ
LTLGLHVQRCQDKGLTYQEAMESKKKYKPRSKSLRLLNKPSVFPKENQMSSKDKYWTF
DKKAVGYRKGIHKVPKWTKISIRKAPKFF"
gene 185957..186292
/gene="CMC1"
/locus_tag="YKL137W"
mRNA 185957..186292
/gene="CMC1"
/locus_tag="YKL137W"
/product="Cmc1p"
CDS 185957..186292
/gene="CMC1"
/locus_tag="YKL137W"
/experiment="EXISTENCE:direct assay:GO:0005507 copper ion
binding [PMID:18443040]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005758
mitochondrial intermembrane space [PMID:19703468]"
/experiment="EXISTENCE:genetic interaction:GO:0033617
mitochondrial cytochrome c oxidase assembly
[PMID:23198688]"
/experiment="EXISTENCE:mutant phenotype:GO:0033617
mitochondrial cytochrome c oxidase assembly
[PMID:18443040|PMID:23198688]"
/note="Copper-binding protein of the mitochondrial
intermembrane space; evolutionarily conserved; may be
involved in delivering copper from the matrix to the
cytochrome c oxidase complex; contains a twin CX9C motif"
/codon_start=1
/product="Cmc1p"
/protein_id="DAA09026.1"
/db_xref="SGD:S000001620"
/translation="MEQNKDPQMISKHSSRLPIWVLSPREEQQARKNLKTETYKKCAN
FVQAMADCAKANGMKVFPTCDKQRDEMKSCLLFYQTDEKYLDGERDKIVLEKINKLEK
LCQKQSSTK"
gene complement(186460..188640)
/gene="APL2"
/locus_tag="YKL135C"
mRNA complement(186460..188640)
/gene="APL2"
/locus_tag="YKL135C"
/product="Apl2p"
CDS complement(186460..188640)
/gene="APL2"
/locus_tag="YKL135C"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0030121 AP-1
adaptor complex [PMID:10564262]"
/experiment="EXISTENCE:direct assay:GO:0030276 clathrin
binding [PMID:10564262]"
/experiment="EXISTENCE:mutant phenotype:GO:0006896 Golgi
to vacuole transport [PMID:17003107]"
/note="Beta-adaptin subunit of the clathrin-associated
protein (AP-1) complex; binds clathrin; involved in
clathrin-dependent Golgi protein sorting; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Apl2p"
/protein_id="DAA09027.1"
/db_xref="SGD:S000001618"
/translation="MPPLDKRIKKFLKDSIRIAPKISGKGELSELRTGLVSQYPQTRK
DAIKKTIQQMTLGKDVSSLFPDVLKNIATIDVEQKKLVYLYVMNYAETHPELCILAVN
TFITDAQDPNPLIRCMAIRTMSMIRVDKILEYIETPLRRTLHDDNAYVRKTAVICVAK
LFQLNKDLCVELGVVEDLVNALDDSNPLVIANATAALIEIHNMDMDAVDLSSLIQSHV
SQFLLALNECTEWARIIILGTLSEYSAKDSLEAQDIIDRVTAHLQHVNPAVVLATIKV
IVRNLPQIEYSSNSLIMKRLSSAFVSLMSTPPEMQYVALKNIRIILEKYPELLTKELR
IFYVKFNDPLYVKLEKIDILVRLVDPSNLKQCTLLLTELKEYAMEYEPEFVSRAIQAL
SQLGIKYAQESFVSKVLDILLELLERQDTIKDDCCISLCDLLRHCPGNDKMAKQVCAV
FNTWSNPEVLLQSDIAKCNYVWLLGQHPNNFSDLESKINIFIENFVQEEALTQMSLLM
TIVRLHATLTGSMLQSVLELATQQTHELDVRDMAMMYWRCLSMPNNESLVNDLCQNKL
PMISNTLEKFSPEVLEKLLMELGTISSIYFKPDSNRRKGKKYVQNIVKGKHIEELESM
AKNEISSKANDDVLLDFDERDDVTNTNAGMLNTLTTLGDLDDLFDFGPSEDATQINTN
DTKAVQGLKELKLGGDSNGISSGGKNNPDVSGGNIVSQDLLDLF"
gene complement(189124..191442)
/gene="OCT1"
/locus_tag="YKL134C"
mRNA complement(189124..191442)
/gene="OCT1"
/locus_tag="YKL134C"
/product="metalloendopeptidase"
CDS complement(189124..191442)
/gene="OCT1"
/locus_tag="YKL134C"
/EC_number="3.4.24.59"
/experiment="EXISTENCE:direct assay:GO:0004222
metalloendopeptidase activity [PMID:8831696]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005759
mitochondrial matrix [PMID:8035833]"
/experiment="EXISTENCE:genetic interaction:GO:0006879
intracellular iron ion homeostasis [PMID:10332043]"
/experiment="EXISTENCE:mutant phenotype:GO:0004222
metalloendopeptidase activity [PMID:8831696]"
/experiment="EXISTENCE:mutant phenotype:GO:0006627 protein
processing involved in protein targeting to mitochondrion
[PMID:8035833]"
/experiment="EXISTENCE:mutant phenotype:GO:0006879
intracellular iron ion homeostasis [PMID:10332043]"
/experiment="EXISTENCE:mutant phenotype:GO:0050821 protein
stabilization [PMID:21525245]"
/note="Mitochondrial intermediate peptidase; cleaves
destabilizing N-terminal residues of a subset of proteins
upon import, after their cleavage by mitochondrial
processing peptidase (Mas1p-Mas2p); may contribute to
mitochondrial iron homeostasis"
/codon_start=1
/product="metalloendopeptidase"
/protein_id="DAA09028.2"
/db_xref="SGD:S000001617"
/translation="MLRTIILKAGSNASIPSPSRQNKLLRFFATAGAVSRTSPGSIKK
IFDDNSYWRNINGQDANNSKISQYLFKKNKTGLFKNPYLTSPDGLRKFSQVSLQQAQE
LLDKMRNDFSESGKLTYIMNLDRLSDTLCRVIDLCEFIRSTHPDDAFVRAAQDCHEQM
FEFMNVLNTDVSLCNILKSVLNNPEVSSKLSAEELKVGKILLDDFEKSGIYMNPDVRE
KFIQLSQEISLVGQEFINHTDYPGSNSVKIPCKDLDNSKVSTFLLKQLNKDVKGQNYK
VPTFGYAAYALLKSCENEMVRKKLWTALHSCSDKQVKRLSHLIKLRAILANLMHKTSY
AEYQLEGKMAKNPKDVQDFILTLMNNTIEKTANELKFIAELKAKDLKKPLTTNTDEIL
KLVRPWDRDYYTGKYFQLNPSNSPNAKEISYYFTLGNVIQGLSDLFQQIYGIRLEPAI
TDEGETWSPDVRRLNVISEEEGIIGIIYCDLFERNGKTSNPAHFTVCCSRQIYPSETD
FSTIQVGENPDGTYFQLPVISLVCNFSPILIASKKSLCFLQLSEVETLFHEMGHAMHS
MLGRTHMQNISGTRCATDFVELPSILMEHFAKDIRILTKIGKHYGTGETIQADMLQRF
MKSTNFLQNCETYSQAKMAMLDQSFHDEKIISDIDNFDVVENYQALERRLKVLVDDQS
NWCGRFGHLFGYGATYYSYLFDRTIASKIWYALFEDDPYSRKNGDKFKKHLLKWGGLK
DPWKCIADVLECPMLEKGGSDAMEFIAQSHKS"
gene complement(191679..193070)
/gene="RCI50"
/locus_tag="YKL133C"
mRNA complement(191679..193070)
/gene="RCI50"
/locus_tag="YKL133C"
/product="Rci50p"
CDS complement(191679..193070)
/gene="RCI50"
/locus_tag="YKL133C"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:26928762]"
/note="Mitochondrial hypothetical protein; not required
for growth of cells lacking the mitochondrial genome;
SWAT-GFP and mCherry fusion proteins localize to the
mitochondria; YKL133C has a paralog, MGR3, that arose from
the whole genome duplication"
/codon_start=1
/product="Rci50p"
/protein_id="DAA09029.2"
/db_xref="SGD:S000001616"
/translation="MWKYLHRSVKNEGTVERLTNLNLFTNHRFKFYSTLKEQSFWRIP
FKRRSKLQKWVLSTGIVSFIAFNIWWVYWPHHTFPKPVAKILRKGLHSEIKKEGANYQ
KSLEYYLEALEECKAENVDLLSDEYTGIEIKIGEMYEKLHMYNDATALYGDMLKKFYN
ELSKTTDKSTKRKFFLLKRDLQILVRFNEINKDSETNATLLIMHLLLAQREFLENSPE
FKNVLSKSELLNNQQLDWKNFKGLPFIGKSKPDYQMHLNSKRKQELKIKEPESEQCVF
MKELLTARDLYTRYCLNRSNLSGALNSKITTLEWMLLADSPLDDILLAQAELGSIFYL
NSEKFEGSLYAIDNEPYKKSEPLELIRSRLQENQNSCLQYSADCYKSIISFANENQYP
KVAMESEMDQRILKALSLAHYGIGVINLHKGRLRASKKELKKAIRISEMIRFNELIEE
AQRELKKVDGTPI"
gene complement(193574..194866)
/gene="RMA1"
/locus_tag="YKL132C"
mRNA complement(193574..194866)
/gene="RMA1"
/locus_tag="YKL132C"
/product="putative tetrahydrofolate synthase"
CDS complement(193574..194866)
/gene="RMA1"
/locus_tag="YKL132C"
/EC_number="6.3.2.17"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/note="Putative dihydrofolate synthetase; similar to E.
coli folylpolyglutamate synthetase/dihydrofolate
synthetase; the authentic, non-tagged protein is detected
in highly purified mitochondria in high-throughput
studies; RMA1 has a paralog, FOL3, that arose from the
whole genome duplication"
/codon_start=1
/product="putative tetrahydrofolate synthase"
/protein_id="DAA09030.1"
/db_xref="SGD:S000001615"
/translation="MDDISGRQTLPRINRLLEHVGNPQDSLSILHIAGTNGKETVSKF
LTSILQHPGQQRQRVLIGRYTTSSLLNAKEEDISINNEAISLIEYSRIEKELIEADSS
LKLQCNNLELLTSVALVYFAKKNCQWCIIETGLAGKQDPGSIIAGQSRVCCAITNVGI
SDEAFLCKFLSQITESSTNKAIFLLDGSNDEFVRNTITKRCHDVGCPLEITDPSLRDY
NVHTDTWGTLEVRLPYSEEEYQIFNLRVAIAVLDFLSKEKKVCISKDQLSQGLISVDW
PRSLHRLDYCYESTSGKKIALLLDNANNAKAARNLACHLRTTYGDTPLTFVIAITTGK
KVSPLLDPLIRPQDYVIVTRFGSVVGMPWIQSLEPVNLLAFIKNRYTRNVNMQPDLQS
VWTFLETSGLKTIVPVIVCGSLYICKELLRLHNCHLPV"
gene complement(195288..196028)
/gene="SHE2"
/locus_tag="YKL130C"
mRNA complement(195288..196028)
/gene="SHE2"
/locus_tag="YKL130C"
/product="She2p"
CDS complement(195288..196028)
/gene="SHE2"
/locus_tag="YKL130C"
/experiment="EXISTENCE:direct assay:GO:0003729 mRNA
binding [PMID:11101531]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:8625407]"
/experiment="EXISTENCE:direct assay:GO:0005789 endoplasmic
reticulum membrane [PMID:16890529|PMID:24056370]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005934 cellular
bud tip [PMID:11032818]"
/experiment="EXISTENCE:direct assay:GO:0008289 lipid
binding [PMID:24056370]"
/experiment="EXISTENCE:direct assay:GO:0008298
intracellular mRNA localization
[PMID:11032818|PMID:24056370]"
/experiment="EXISTENCE:direct assay:GO:1990825
sequence-specific mRNA binding [PMID:28092367]"
/experiment="EXISTENCE:mutant phenotype:GO:0007533 mating
type switching [PMID:8625407]"
/experiment="EXISTENCE:mutant phenotype:GO:0008298
intracellular mRNA localization [PMID:28092367]"
/note="RNA-binding protein that binds specific mRNAs and
interacts with She3p; part of the mRNA localization
machinery that restricts accumulation of certain proteins
to the bud; binds to ER-derived membranes and targets
mRNAs to cortical ER"
/codon_start=1
/product="She2p"
/protein_id="DAA09031.1"
/db_xref="SGD:S000001613"
/translation="MSKDKDIKVTPGTCELVEQILALLSRYLSSYIHVLNKFISHLRR
VATLRFERTTLIKFVKKLRFYNDCVLSYNASEFINEGKNELDPEADSFDKVILPIASM
FVKCVETFDLLNYYLTQSLQKEILSKTLNEDLTLTAESILAIDDTYNHFVKFSQWMIE
SLRIGSNLLDLEVVQFAIKCADEDGTNIGETDNIFLQEILPVNSEEEFQTLSAAWHSI
LDGKLSALDEEFDVVATKWHDKFGKLKN"
rep_origin 196042..196287
/note="ARS1126; Autonomously Replicating Sequence"
/db_xref="SGD:S000119036"
gene complement(196349..200167)
/gene="MYO3"
/locus_tag="YKL129C"
mRNA complement(196349..200167)
/gene="MYO3"
/locus_tag="YKL129C"
/product="myosin 3"
CDS complement(196349..200167)
/gene="MYO3"
/locus_tag="YKL129C"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:2000601 positive
regulation of Arp2/3 complex-mediated actin nucleation
[PMID:11604421]"
/experiment="EXISTENCE:genetic interaction:GO:0051666
actin cortical patch localization [PMID:18177206]"
/experiment="EXISTENCE:genetic interaction:GO:0061709
reticulophagy [PMID:35101986]"
/note="One of two type I myosins; localizes to actin
cortical patches; deletion of MYO3 has little effect on
growth, but myo3 myo5 double deletion causes severe
defects in growth and actin cytoskeleton organization;
MYO3 has a paralog, MYO5, that arose from the whole genome
duplication"
/codon_start=1
/product="myosin 3"
/protein_id="DAA09032.2"
/db_xref="SGD:S000001612"
/translation="MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLL
SKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVP
PHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKI
KDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVV
GQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGT
LEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVD
ASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVN
VSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYE
REKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLF
NSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFP
DDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLH
QVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLIL
RDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAA
IKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKG
SYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKY
TQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIM
IKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNP
GGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYN
PKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSK
GVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGD
IVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSS
QIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDD
NDDGDDDDDW"
gene complement(200884..201771)
/gene="PMU1"
/locus_tag="YKL128C"
mRNA complement(200884..201771)
/gene="PMU1"
/locus_tag="YKL128C"
/product="putative phosphomutase"
CDS complement(200884..201771)
/gene="PMU1"
/locus_tag="YKL128C"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
[PMID:36164978]"
/note="Putative phosphomutase; contains a region
homologous to the active site of phosphomutases;
overexpression suppresses the histidine auxotrophy of an
ade3 ade16 ade17 triple mutant and the temperature
sensitivity of a tps2 mutant; localizes to cytosol an
peroxisomes"
/codon_start=1
/product="putative phosphomutase"
/protein_id="DAA09033.1"
/db_xref="SGD:S000001611"
/translation="MSLRAVPGYFAAYPSEGFQGLDSTKYDHLELINHKNWKELYHAI
PRNTKNRHYKLLILARHGQGYHNAAILRYGMEKWDAYWSLLSGDEHGEWLDSKLTPLG
KDQVRRTGSNVLLPMAKQLGMLPHVFFSSPMRRCLETFIESWTPVLAETQELPAGTKI
STRIIEGLRETLGSHTCDKRVAHSMAVDEYQDFSTESGHTVHWQYVPDYPEDDELWLP
DHRETCAEMDKRTLNGLFELFNQLSSEEKFISLTCHSGVIQSVLRNLQHPPIYNLDTG
KVVAVVVEVPVNTADRGRL"
repeat_region complement(202644..202983)
/note="Ty3 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007054"
gene 202999..203071
/locus_tag="YNCK0007W"
tRNA 202999..203071
/locus_tag="YNCK0007W"
/product="tRNA-Lys"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:8915539]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:8915539]"
/experiment="EXISTENCE:mutant phenotype:GO:0030533 triplet
codon-amino acid adaptor activity [PMID:17560369]"
/experiment="EXISTENCE:mutant phenotype:GO:0032543
mitochondrial translation [PMID:17560369]"
/note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
analysis; a small portion is imported into mitochondria
via interaction with mt lysyl-tRNA synthetase Msk1p and is
necessary to decode AAG codons at high temperature, when
base modification of mt-encoded tRNA-Lys is reduced"
/db_xref="SGD:S000006626"
gene 203541..205253
/gene="PGM1"
/locus_tag="YKL127W"
mRNA 203541..205253
/gene="PGM1"
/locus_tag="YKL127W"
/product="phosphoglucomutase PGM1"
CDS 203541..205253
/gene="PGM1"
/locus_tag="YKL127W"
/EC_number="5.4.2.2"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:8385141]"
/experiment="EXISTENCE:genetic interaction:GO:0004614
phosphoglucomutase activity [PMID:8119301]"
/experiment="EXISTENCE:genetic interaction:GO:0005978
glycogen biosynthetic process [PMID:9252577]"
/experiment="EXISTENCE:genetic interaction:GO:0005992
trehalose biosynthetic process [PMID:9252577]"
/experiment="EXISTENCE:genetic interaction:GO:0006011
UDP-glucose metabolic process [PMID:9252577]"
/experiment="EXISTENCE:genetic interaction:GO:0019255
glucose 1-phosphate metabolic process [PMID:8119301]"
/experiment="EXISTENCE:genetic interaction:GO:0019388
galactose catabolic process [PMID:8119301]"
/experiment="EXISTENCE:genetic interaction:GO:0051156
glucose 6-phosphate metabolic process [PMID:8119301]"
/note="Phosphoglucomutase, minor isoform; catalyzes the
conversion from glucose-1-phosphate to
glucose-6-phosphate, which is a key step in hexose
metabolism; PGM1 has a paralog, PGM2, that arose from the
whole genome duplication"
/codon_start=1
/product="phosphoglucomutase PGM1"
/protein_id="DAA09034.1"
/db_xref="SGD:S000001610"
/translation="MSLLIDSVPTVAYKDQKPGTSGLRKKTKVFMDEPHYTENFIQAT
MQSIPNGSEGTTLVVGGDGRFYNDVIMNKIAAVGAANGVRKLVIGQGGLLSTPAASHI
IRTYEEKCTGGGIILTASHNPGGPENDLGIKYNLPNGGPAPESVTNAIWEASKKLTHY
KIIKNFPKLNLNKLGKNQKYGPLLVDIIDPAKAYVQFLKEIFDFDLIKSFLAKQRKDK
GWKLLFDSLNGITGPYGKAIFVDEFGLPAEEVLQNWHPLPDFGGLHPDPNLTYARTLV
DRVDREKIAFGAASDGDGDRNMIYGYGPAFVSPGDSVAIIAEYAPEIPYFAKQGIYGL
ARSFPTSSAIDRVAAKKGLRCYEVPTGWKFFCALFDAKKLSICGEESFGTGSNHIREK
DGLWAIIAWLNILAIYHRRNPEKEASIKTIQDEFWNEYGRTFFTRYDYEHIECEQAEK
VVALLSEFVSRPNVCGSHFPADESLTVIDCGDFSYRDLDGSISENQGLFVKFSNGTKF
VLRLSGTGSSGATIRLYVEKYTDKKENYGQTADVFLKPVINSIVKFLRFKEILGTDEP
TVRT"
gene 205707..207749
/gene="YPK1"
/locus_tag="YKL126W"
/gene_synonym="SLI2"
mRNA 205707..207749
/gene="YPK1"
/locus_tag="YKL126W"
/gene_synonym="SLI2"
/product="serine/threonine protein kinase YPK1"
CDS 205707..207749
/gene="YPK1"
/locus_tag="YKL126W"
/gene_synonym="SLI2"
/EC_number="2.7.11.1"
/experiment="EXISTENCE:direct assay:GO:0004674 protein
serine/threonine kinase activity
[PMID:19966303|PMID:22080611|PMID:29352143]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:10825204|PMID:12221112]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:10825204]"
/experiment="EXISTENCE:direct assay:GO:0005935 cellular
bud neck [PMID:10825204]"
/experiment="EXISTENCE:genetic interaction:GO:0006650
glycerophospholipid metabolic process [PMID:25258318]"
/experiment="EXISTENCE:genetic interaction:GO:0060237
regulation of fungal-type cell wall organization
[PMID:12221112]"
/experiment="EXISTENCE:genetic interaction:GO:0070941
eisosome assembly [PMID:18296441]"
/experiment="EXISTENCE:mutant phenotype:GO:0004674 protein
serine/threonine kinase activity
[PMID:10825204|PMID:26274562]"
/experiment="EXISTENCE:mutant phenotype:GO:0006650
glycerophospholipid metabolic process [PMID:25258318]"
/experiment="EXISTENCE:mutant phenotype:GO:0060237
regulation of fungal-type cell wall organization
[PMID:12221112]"
/experiment="EXISTENCE:mutant phenotype:GO:0061093
negative regulation of phospholipid translocation
[PMID:19966303]"
/experiment="EXISTENCE:mutant phenotype:GO:0071311
cellular response to acetate [PMID:27671892]"
/experiment="EXISTENCE:mutant phenotype:GO:0090155
negative regulation of sphingolipid biosynthetic process
[PMID:22080611]"
/note="S/T protein kinase; required for PM lipid and
protein homeostasis; involved in sphingolipid-mediated and
cell integrity signaling pathways and endocytosis;
phosphorylates and downregulates Fpk1p; phosphorylates and
inactivates Orm1p/2p when sphingolipid synthesis is
compromised; role in TORC1/2-dependent Rps6a/b
phosphorylation; phosphorylated and activated by TORC2 and
by Pkh1/2p in the presence of phytosphingosine; human
homolog SGK1 complements the null and inviability of a
ypk1 ypk2 mutant"
/codon_start=1
/product="serine/threonine protein kinase YPK1"
/protein_id="DAA09035.1"
/db_xref="SGD:S000001609"
/translation="MYSWKSKFKFGKSKEEKEAKHSGFFHSSKKEEQQNNQATAGEHD
ASITRSSLDRKGTINPSNSSVVPVRVSYDASSSTSTVRDSNGGNSENTNSSQNLDETA
NIGSTGTPNDATSSSGMMTIKVYNGDDFILPFPITSSEQILNKLLASGVPPPHKEISK
EVDALIAQLSRVQIKNQGPADEDLISSESAAKFIPSTIMLPGSSTLNPLLYFTIEFDN
TVATIEAEYGTIAKPGFNKISTFDVTRKLPYLKIDVFARIPSILLPSKTWQQEMGLQD
EKLQTIFDKINSNQDIHLDSFHLPINLSFDSAASIRLYNHHWITLDNGLGKINISIDY
KPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHT
LAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFY
TAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGT
PEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPD
GFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVS
NSMDTSNFDEEFTREKPIDSVVDEYLSESVQKQFGGWTYVGNEQLGSSMVQGRSIR"
gene 208247..210130
/gene="RRN3"
/locus_tag="YKL125W"
mRNA 208247..210130
/gene="RRN3"
/locus_tag="YKL125W"
/product="rDNA-binding RNA polymerase I transcriptional
factor"
CDS 208247..210130
/gene="RRN3"
/locus_tag="YKL125W"
/experiment="EXISTENCE:direct assay:GO:0000182 rDNA
binding [PMID:23393135]"
/experiment="EXISTENCE:direct assay:GO:0001042 RNA
polymerase I core binding [PMID:11032814]"
/experiment="EXISTENCE:direct assay:GO:0001179 RNA
polymerase I general transcription initiation factor
binding [PMID:11032814]"
/experiment="EXISTENCE:direct assay:GO:0001181 RNA
polymerase I general transcription initiation factor
activity [PMID:11032814]"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:19416370]"
/experiment="EXISTENCE:genetic interaction:GO:0001181 RNA
polymerase I general transcription initiation factor
activity [PMID:11032814]"
/experiment="EXISTENCE:mutant phenotype:GO:0006361
transcription initiation at RNA polymerase I promoter
[PMID:8670901]"
/experiment="EXISTENCE:physical interaction:GO:0001042 RNA
polymerase I core binding [PMID:11032814]"
/experiment="EXISTENCE:physical interaction:GO:0001179 RNA
polymerase I general transcription initiation factor
binding [PMID:11032814]"
/experiment="EXISTENCE:physical interaction:GO:0001181 RNA
polymerase I general transcription initiation factor
activity [PMID:11032814]"
/note="Protein required for transcription of rDNA by RNA
polymerase I; transcription factor independent of DNA
template; involved in recruitment of RNA polymerase I to
rDNA; structure reveals unique HEAT repeat fold and a
surface serine patch; phosphorylation of serine patch
impairs cell growth and reduces RNA polymerase I binding
in vitro and RNA polymerase I recruitment to the rDNA gene
in vivo"
/codon_start=1
/product="rDNA-binding RNA polymerase I transcriptional
factor"
/protein_id="DAA09036.1"
/db_xref="SGD:S000001608"
/translation="MMAFENTSKRPPQDFVAPIDQKKRKVQFSDSTGLVTLQPEEIKD
EVFSAAMYSRFVKSALDDLDKNDSTQIGIIANQVALPSKNPERINDKNLNILLDILSS
NINRIESSRGTFLIQSIINFEKWWELPPHTLSKYIYFIKILCSSIPKWWQDVSMILVS
CFILPIKQTVCHHDMLKYFLRMIPSSMGFIDTYLAKFFPNKNDTRRKLVNYTSNLLKL
RGYCSELGFQIWSLLIEKIISIDVELQNELDELDDDVDDDDLEEVDLEDDDDLDDDSG
DDDDENCGNSNEELRSGAADGSQSDSEDMDIIEGMDGTEEYNVELTQGIKELSTKLDS
ILTLVSTHVEEQVTPESLESGEGVGVFNTLTTLFKTHVLPTYYTRSIQYIMFHVSQQQ
LELMDSFLVTLIDISFAVNEAAEKKIKSLQYLGSYIARAKKLSRTQIIFVASYLTSWL
NRYVIEREEEVDQRGGMERFKHFYAAFQALCYIFCFRHNIFRDTDGNWECELDKFFQR
MVISKFNPLKFCNENVMLMFARIAQQESVAYCFSIIENNNNERLRGIIGKADSDKKEN
SAQANTTSSSWSLATRQQFIDLQSYFPYDPLFLKNYKILMKEYYIEWSEASGEYESDG
SDD"
gene 210593..212332
/gene="SSH4"
/locus_tag="YKL124W"
/gene_synonym="MLF4"
mRNA 210593..212332
/gene="SSH4"
/locus_tag="YKL124W"
/gene_synonym="MLF4"
/product="Ssh4p"
CDS 210593..212332
/gene="SSH4"
/locus_tag="YKL124W"
/gene_synonym="MLF4"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:17287526]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:genetic interaction:GO:0016192
vesicle-mediated transport [PMID:17287526]"
/experiment="EXISTENCE:genetic interaction:GO:0043328
protein transport to vacuole involved in
ubiquitin-dependent protein catabolic process via the
multivesicular body sorting pathway
[PMID:30361468|PMID:18367543]"
/experiment="EXISTENCE:mutant phenotype:GO:1990756
ubiquitin ligase-substrate adaptor activity
[PMID:30361468]"
/note="Specificity factor required for Rsp5p-dependent
ubiquitination; also required for sorting of cargo
proteins at the multivesicular body; identified as a
high-copy suppressor of a SHR3 deletion, increasing
steady-state levels of amino acid permeases"
/codon_start=1
/product="Ssh4p"
/protein_id="DAA09037.1"
/db_xref="SGD:S000001607"
/translation="MYVTFNEALDSSFGNLESPNHDFKVGDPNMVPTPPMDSDSAAIS
LAFLISLSITFAILMLILVVIAAYVTFCGDDESEYDEENALGTRTSGTLHSLFGKKHS
GILLDSSFASPGGFDDEIVLQERELEELPKMSAYEVELYIRAKEFQMMSPPMVKDFGT
YLDSDDQQFIKDRGIQSYFLLPSINDNIDEYGNFLPSFIVQDKLDIQFSKFNKSSSTV
MNYPLPHNRKDAVYFEVKIFRHIQKSNSIFSIGLTTVPYPYFRVPGMAKYSIAYESTG
KLRINNPFTASTLLPKLEEGDTVGFGYRYKTGTIFITHNGKKLMDVTQNIGIDLFIGI
GAFNAAYTRTYTRDGLLEDPDNVSFREALSEGKDIEVAKDLQRVHDPHDESDEMTSDE
VELHVNLGQVGFVFIEANVKKYAFGSVYGQIGIPPAYNGTEIKKDTILQKGEELPPRY
ADTDNFFGSMKVKEGSSSRITAQTSKPLWSVGTYERISSNFDRENNVYHDSLETDDNN
TDNNVNNNDENAGCNENSPLLEDDGNKRPENSNTPREVSDGAINKNPRNKSTKKRQRN
RGKSSKKKNRSRK"
gene complement(212495..212998)
/gene="SRP21"
/locus_tag="YKL122C"
mRNA complement(212495..212998)
/gene="SRP21"
/locus_tag="YKL122C"
/product="signal recognition particle subunit SRP21"
CDS complement(212495..212998)
/gene="SRP21"
/locus_tag="YKL122C"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:11914276]"
/experiment="EXISTENCE:direct assay:GO:0005786 signal
recognition particle, endoplasmic reticulum targeting
[PMID:7925282]"
/experiment="EXISTENCE:direct assay:GO:0006614
SRP-dependent cotranslational protein targeting to
membrane [PMID:10921896]"
/note="Subunit of the signal recognition particle (SRP);
SRP functions in protein targeting to the endoplasmic
reticulum membrane; not found in mammalian SRP; forms a
pre-SRP structure in the nucleolus that is translocated to
the cytoplasm"
/codon_start=1
/product="signal recognition particle subunit SRP21"
/protein_id="DAA09038.1"
/db_xref="SGD:S000001605"
/translation="MSVKPIDNYITNSVRLFEVNPSQTLFSISYKPPTQKTDTKVSFR
THNSHLSLNYKFTTNKSKDVSRLLSALGPRGVSITPGKIEKIAQSKKKNNKIKESSKK
IKGKSIQDIVGLATLIVNTDVEKSDPAAKKTATEPKQKANAVQNNNGNSAASKKKKNK
NKGKKKR"
rep_origin 213439..213743
/note="ARS1127; Autonomously Replicating Sequence"
/db_xref="SGD:S000119037"
gene 214142..216700
/gene="DGR2"
/locus_tag="YKL121W"
mRNA 214142..216700
/gene="DGR2"
/locus_tag="YKL121W"
/product="Dgr2p"
CDS 214142..216700
/gene="DGR2"
/locus_tag="YKL121W"
/note="hypothetical protein; null mutant is resistant to
2-deoxy-D-glucose and displays abnormally elongated buds;
DGR2 has a paralog, YMR102C, that arose from the whole
genome duplication"
/codon_start=1
/product="Dgr2p"
/protein_id="DAA09039.1"
/db_xref="SGD:S000001604"
/translation="MFKSKTSTLSYDETPNSNEGDRNATPVNPKEKSQTKHLNIPGDR
SRHSSIADSKRSSSRYDGGYSADIIPAQLRFIDNIDYGTRLRKTLHRNSVVSNGYNKL
SENDRWYFDLFDRKYFENYLEEPTYIKIFKKKEGLEQFDRMFLAQELKIPDVYKSTTY
QGEPAVANSELFKNSICCCTFSHDGKYMVIGCKDGSLHLWKVINSPVKRSEMGRSEKS
VSASRANSLKIQRHLASISSHNGSISSNDLKPSDQFEGPSKQLHLYAPVFYSDVFRVF
MEHALDILDANWSKNGFLITASMDKTAKLWHPERKYSLKTFVHPDFVTSAIFFPNDDR
FIITGCLDHRCRLWSILDNEVSYAFDCKDLITSLTLSPPGGEYTIIGTFNGYIYVLLT
HGLKFVSSFHVSDKSTQGTTKNSFHPSSEYGKVQHGPRITGLQCFFSKVDKNLRLIVT
TNDSKIQIFDLNEKKPLELFKGFQSGSSRHRGQFLMMKNEPVVFTGSDDHWFYTWKMQ
SFNLSAEMNCTAPHRKKRLSGSMSLKGLLRIVSNKSTNDECLTETSNQSSSHTFTNSS
KNVLQTQTVGSQAIKNNHYISFHAHNSPVTCASIAPDVAIKNLSLSNDLIFELTSQYF
KEMGQNYSESKETCDNKPNHPVTETGGFSSNLSNVVNNVGTILITTDSQGLIRVFRTD
ILPEIRKKIIEKFHEYNLFHLEAAGKINNHNNDSILENRMDERSSTEDNEFSTTPPSN
THNSRPSHDFCELHPNNSPVISGMPSRASAIFKNSIFNKSNGSFISLKSRSESTSSTV
FGPHDIPRVSTTYPKLKCDVCNGSNFECASKNPIAGGDSGFTCADCGTILNNFR"
gene 217344..218318
/gene="OAC1"
/locus_tag="YKL120W"
mRNA 217344..218318
/gene="OAC1"
/locus_tag="YKL120W"
/product="Oac1p"
CDS 217344..218318
/gene="OAC1"
/locus_tag="YKL120W"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005743
mitochondrial inner membrane [PMID:10428783]"
/experiment="EXISTENCE:direct assay:GO:0008272 sulfate
transport [PMID:10428783]"
/experiment="EXISTENCE:direct assay:GO:0015116 sulfate
transmembrane transporter activity [PMID:10428783]"
/experiment="EXISTENCE:direct assay:GO:0015131
oxaloacetate transmembrane transporter activity
[PMID:10428783]"
/experiment="EXISTENCE:direct assay:GO:0015729
oxaloacetate transport [PMID:10428783]"
/experiment="EXISTENCE:direct assay:GO:0034658
isopropylmalate transmembrane transporter activity
[PMID:18682385]"
/experiment="EXISTENCE:direct assay:GO:0034659
isopropylmalate transport [PMID:18682385]"
/experiment="EXISTENCE:direct assay:GO:1901239
malonate(1-) transmembrane transporter activity
[PMID:10428783]"
/note="Mitochondrial inner membrane transporter;
transports oxaloacetate, sulfate, thiosulfate, and
isopropylmalate; member of the mitochondrial carrier
family"
/codon_start=1
/product="Oac1p"
/protein_id="DAA09040.1"
/db_xref="SGD:S000001603"
/translation="MSSDNSKQDKQIEKTAAQKISKFGSFVAGGLAACIAVTVTNPIE
LIKIRMQLQGEMSASAAKVYKNPIQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSRL
GFYEPIRSSLNQLFFPDQEPHKVQSVGVNVFSGAASGIIGAVIGSPLFLVKTRLQSYS
EFIKIGEQTHYTGVWNGLVTIFKTEGVKGLFRGIDAAILRTGAGSSVQLPIYNTAKNI
LVKNDLMKDGPALHLTASTISGLGVAVVMNPWDVILTRIYNQKGDLYKGPIDCLVKTV
RIEGVTALYKGFAAQVFRIAPHTIMCLTFMEQTMKLVYSIESRVLGHN"
gene complement(218570..219217)
/gene="VPH2"
/locus_tag="YKL119C"
/gene_synonym="CLS10"
/gene_synonym="VMA12"
mRNA complement(218570..219217)
/gene="VPH2"
/locus_tag="YKL119C"
/gene_synonym="CLS10"
/gene_synonym="VMA12"
/product="Vph2p"
CDS complement(218570..219217)
/gene="VPH2"
/locus_tag="YKL119C"
/gene_synonym="CLS10"
/gene_synonym="VMA12"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005789 endoplasmic
reticulum membrane [PMID:9325326]"
/experiment="EXISTENCE:mutant phenotype:GO:0007035
vacuolar acidification [PMID:1628805]"
/experiment="EXISTENCE:mutant phenotype:GO:0070072
vacuolar proton-transporting V-type ATPase complex
assembly [PMID:9325326]"
/experiment="EXISTENCE:physical interaction:GO:1990871
Vma12-Vma22 assembly complex [PMID:9660861]"
/note="Integral membrane protein required for V-ATPase
function; not an actual component of the vacuolar
H+-ATPase (V-ATPase) complex; functions in the assembly of
the V-ATPase; localized to the endoplasmic reticulum (ER);
involved in methionine restriction extension of
chronological lifespan in an autophagy-dependent manner"
/codon_start=1
/product="Vph2p"
/protein_id="DAA09041.1"
/db_xref="SGD:S000001602"
/translation="MFEIKLNDRITEFLRKFKNSAKSNEGIDEDIDLFLKRHAIPMQS
LLFYVKEYRKDSDLQCSIKELLKPLEFEFKPKAVRGLHYSEDFKKKLEFLKYQEQELE
YQSMVKRSKSVFSLQEDDELTPSQINKQIKEQVTTVFNVLVSVISVVVAIWYWTGSST
NFPVHVRLLLCLFFGILVLVADVVVYNSYLKKLEEAKVKEKTKVEKKKVLSKITL"
repeat_region complement(219395..219723)
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007051"
gene 219895..219967
/locus_tag="YNCK0008W"
tRNA 219895..219967
/locus_tag="YNCK0008W"
/product="tRNA-Ala"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon AGC (converted to IGC in the mature tRNA),
decodes GCU and GCC codons into alanine, one of 16 nuclear
tRNAs for alanine"
/db_xref="SGD:S000006515"
gene 220324..220974
/gene="SBA1"
/locus_tag="YKL117W"
/gene_synonym="CST18"
mRNA 220324..220974
/gene="SBA1"
/locus_tag="YKL117W"
/gene_synonym="CST18"
/product="Hsp90 cochaperone SBA1"
CDS 220324..220974
/gene="SBA1"
/locus_tag="YKL117W"
/gene_synonym="CST18"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:10207098]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:10207098]"
/experiment="EXISTENCE:direct assay:GO:0032212 positive
regulation of telomere maintenance via telomerase
[PMID:17389357]"
/experiment="EXISTENCE:direct assay:GO:0043392 negative
regulation of DNA binding [PMID:23022381]"
/experiment="EXISTENCE:mutant phenotype:GO:0006457 protein
folding [PMID:9632755]"
/experiment="EXISTENCE:mutant phenotype:GO:0032212
positive regulation of telomere maintenance via telomerase
[PMID:17389357]"
/experiment="EXISTENCE:mutant phenotype:GO:0051087
protein-folding chaperone binding [PMID:9632755]"
/experiment="EXISTENCE:physical interaction:GO:0006457
protein folding [PMID:9632755]"
/experiment="EXISTENCE:physical interaction:GO:0051087
protein-folding chaperone binding [PMID:9632755]"
/note="Co-chaperone that binds and regulates Hsp90 family
chaperones; plays a role in determining prion variants;
important for pp60v-src activity in yeast; homologous to
the mammalian p23 proteins, and like p23 can regulate
telomerase activity; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Hsp90 cochaperone SBA1"
/protein_id="DAA09042.1"
/db_xref="SGD:S000001600"
/translation="MSDKVINPQVAWAQRSSTTDPERNYVLITVSIADCDAPELTIKP
SYIELKAQSKPHVGDENVHHYQLHIDLYKEIIPEKTMHKVANGQHYFLKLYKKDLESE
YWPRLTKEKVKYPYIKTDFDKWVDEDEQDEVEAEGNDAAQGMDFSQMMGGAGGAGGAG
GMDFSQMMGGAGGAGSPDMAQLQQLLAQSGGNLDMGDFKENDEEDEEEEIEPEVKA"
gene complement(221344..222900)
/gene="PRR1"
/locus_tag="YKL116C"
mRNA complement(221344..222900)
/gene="PRR1"
/locus_tag="YKL116C"
/product="serine/threonine protein kinase PRR1"
CDS complement(221344..222900)
/gene="PRR1"
/locus_tag="YKL116C"
/EC_number="2.7.11.1"
/experiment="EXISTENCE:direct assay:GO:0004672 protein
kinase activity [PMID:16319894]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:genetic interaction:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:11337509]"
/experiment="EXISTENCE:genetic interaction:GO:0031138
negative regulation of conjugation with cellular fusion
[PMID:11337509]"
/experiment="EXISTENCE:mutant phenotype:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:11337509]"
/experiment="EXISTENCE:mutant phenotype:GO:0031138
negative regulation of conjugation with cellular fusion
[PMID:11337509]"
/note="Serine/threonine protein kinase; inhibits pheromone
induced signaling downstream of MAPK, possibly at the
level of the Ste12p transcription factor"
/codon_start=1
/product="serine/threonine protein kinase PRR1"
/protein_id="DAA09043.1"
/db_xref="SGD:S000001599"
/translation="MDEYSSIYSQPKTPRLKQEGFPDSIGDQHEKALIDENGEEDKKM
ASTEGTTGDSRSTPLTVSIPTFENVQALPTPMTYTPLSPGNLSMSPIDQSSLNIPKRR
SHARLLDDMLSVTQPNQRVVSELIAPANLSPQRVVSLPTVTEEALVNDSVDSDNYTKE
PYFPESSSSTEKCDDDIFQGFLLDHWDRPLLWKKVRPIGSGNFSTVLLYELMDQSNPK
LKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLG
INNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRI
FTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLC
KKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFDPPPN
ASARQRSRATSHRIARFDWRWYRLSDYKTNVGKQIVENTLTRKNQRWSINEIYESPFV
KTIADTLSFS"
gene complement(223352..224455)
/gene="APN1"
/locus_tag="YKL114C"
mRNA complement(223352..224455)
/gene="APN1"
/locus_tag="YKL114C"
/product="DNA-(apurinic or apyrimidinic site) lyase APN1"
CDS complement(223352..224455)
/gene="APN1"
/locus_tag="YKL114C"
/experiment="EXISTENCE:direct assay:GO:0003906
DNA-(apurinic or apyrimidinic site) endonuclease activity
[PMID:12767225]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:7690756]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:11238901]"
/experiment="EXISTENCE:direct assay:GO:0006284
base-excision repair [PMID:9295360]"
/experiment="EXISTENCE:direct assay:GO:0008081 phosphoric
diester hydrolase activity [PMID:3056935]"
/experiment="EXISTENCE:direct assay:GO:0008311
double-stranded DNA 3'-5' DNA exonuclease activity
[PMID:16024777]"
/experiment="EXISTENCE:direct assay:GO:0017005
3'-tyrosyl-DNA phosphodiesterase activity [PMID:12397185]"
/experiment="EXISTENCE:mutant phenotype:GO:0003906
DNA-(apurinic or apyrimidinic site) endonuclease activity
[PMID:1693433]"
/note="Major apurinic/apyrimidinic endonuclease; 3'-repair
diesterase; involved in repair of DNA damage by oxidation
and alkylating agents; also functions as a 3'-5'
exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine;
genetically interacts with NTG1 to maintain mitochondrial
genome integrity"
/codon_start=1
/product="DNA-(apurinic or apyrimidinic site) lyase APN1"
/protein_id="DAA09044.1"
/db_xref="SGD:S000001597"
/translation="MPSTPSFVRSAVSKYKFGAHMSGAGGISNSVTNAFNTGCNSFAM
FLKSPRKWVSPQYTQEEIDKFKKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSY
ESFMDDLNRCEQLGIGLYNLHPGSTLKGDHQLQLKQLASYLNKAIKETKFVKIVLENM
AGTGNLVGSSLVDLKEVIGMIEDKSRIGVCIDTCHTFAAGYDISTTETFNNFWKEFND
VIGFKYLSAVHLNDSKAPLGANRDLHERLGQGYLGIDVFRMIAHSEYLQGIPIVLETP
YENDEGYGNEIKLMEWLESKSESELLEDKEYKEKNDTLQKLGAKSRKEQLDKFEVKQK
KRAGGTKRKKATAEPSDNDILSQMTKKRKTKKE"
gene complement(224727..225875)
/gene="RAD27"
/locus_tag="YKL113C"
/gene_synonym="ERC11"
/gene_synonym="FEN1"
/gene_synonym="RTH1"
mRNA complement(224727..225875)
/gene="RAD27"
/locus_tag="YKL113C"
/gene_synonym="ERC11"
/gene_synonym="FEN1"
/gene_synonym="RTH1"
/product="multifunctional nuclease RAD27"
CDS complement(224727..225875)
/gene="RAD27"
/locus_tag="YKL113C"
/gene_synonym="ERC11"
/gene_synonym="FEN1"
/gene_synonym="RTH1"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:36672839|PMID:14562095|PMID:19699691|PMID:22932476]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:19699691]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:22932476]"
/experiment="EXISTENCE:direct assay:GO:0006303
double-strand break repair via nonhomologous end joining
[PMID:15342630]"
/experiment="EXISTENCE:direct assay:GO:0008409 5'-3'
exonuclease activity [PMID:9166764]"
/experiment="EXISTENCE:direct assay:GO:0017108 5'-flap
endonuclease activity [PMID:11825897|PMID:36672839]"
/experiment="EXISTENCE:direct assay:GO:0043137 DNA
replication, removal of RNA primer
[PMID:16837458|PMID:36672839]"
/experiment="EXISTENCE:genetic interaction:GO:0035753
maintenance of DNA trinucleotide repeats [PMID:16079237]"
/experiment="EXISTENCE:mutant phenotype:GO:0007534 gene
conversion at mating-type locus [PMID:10025407]"
/experiment="EXISTENCE:mutant phenotype:GO:0035753
maintenance of DNA trinucleotide repeats [PMID:16079237]"
/note="5' to 3' exonuclease, 5' flap endonuclease;
required for Okazaki fragment processing and maturation,
for long-patch base-excision repair and large loop repair
(LLR), ribonucleotide excision repair; cleaves off RNA
flap in a RNA:DNA hybrid intermediate during processing of
DNA lagging strand; relocalizes to the cytosol in response
to hypoxia; member of the S. pombe RAD2/FEN1 family"
/codon_start=1
/product="multifunctional nuclease RAD27"
/protein_id="DAA09045.1"
/db_xref="SGD:S000001596"
/translation="MGIKGLNAIISEHVPSAIRKSDIKSFFGRKVAIDASMSLYQFLI
AVRQQDGGQLTNEAGETTSHLMGMFYRTLRMIDNGIKPCYVFDGKPPDLKSHELTKRS
SRRVETEKKLAEATTELEKMKQERRLVKVSKEHNEEAQKLLGLMGIPYIIAPTEAEAQ
CAELAKKGKVYAAASEDMDTLCYRTPFLLRHLTFSEAKKEPIHEIDTELVLRGLDLTI
EQFVDLCIMLGCDYCESIRGVGPVTALKLIKTHGSIEKIVEFIESGESNNTKWKIPED
WPYKQARMLFLDPEVIDGNEINLKWSPPKEKELIEYLCDDKKFSEERVKSGISRLKKG
LKSGIQGRLDGFFQVVPKTKEQLAAAAKRAQENKKLNKNKNKVTKGRR"
gene 226570..228765
/gene="ABF1"
/locus_tag="YKL112W"
/gene_synonym="BAF1"
/gene_synonym="EBF2"
/gene_synonym="OBF1"
/gene_synonym="REB2"
/gene_synonym="SBF1"
mRNA 226570..228765
/gene="ABF1"
/locus_tag="YKL112W"
/gene_synonym="BAF1"
/gene_synonym="EBF2"
/gene_synonym="OBF1"
/gene_synonym="REB2"
/gene_synonym="SBF1"
/product="DNA-binding protein ABF1"
CDS 226570..228765
/gene="ABF1"
/locus_tag="YKL112W"
/gene_synonym="BAF1"
/gene_synonym="EBF2"
/gene_synonym="OBF1"
/gene_synonym="REB2"
/gene_synonym="SBF1"
/experiment="EXISTENCE:direct assay:GO:0000113
nucleotide-excision repair factor 4 complex
[PMID:10601031]"
/experiment="EXISTENCE:direct assay:GO:0000978 RNA
polymerase II cis-regulatory region sequence-specific DNA
binding [PMID:7663308|PMID:27016735]"
/experiment="EXISTENCE:direct assay:GO:0001228 DNA-binding
transcription activator activity, RNA polymerase
II-specific [PMID:7663308]"
/experiment="EXISTENCE:direct assay:GO:0003688 DNA
replication origin binding [PMID:3281162|PMID:16824194]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:15522095]"
/experiment="EXISTENCE:direct assay:GO:0006261
DNA-templated DNA replication [PMID:11756546]"
/experiment="EXISTENCE:direct assay:GO:0006338 chromatin
remodeling [PMID:10684934|PMID:11713306]"
/experiment="EXISTENCE:direct assay:GO:0043565
sequence-specific DNA binding
[PMID:3275867|PMID:7663308|PMID:19111667]"
/experiment="EXISTENCE:direct assay:GO:0044374
sequence-specific DNA binding, bending [PMID:8206955]"
/experiment="EXISTENCE:direct assay:GO:0070911 global
genome nucleotide-excision repair [PMID:15177043]"
/experiment="EXISTENCE:genetic interaction:GO:0006338
chromatin remodeling [PMID:10684934|PMID:11713306]"
/experiment="EXISTENCE:mutant phenotype:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:15192094]"
/experiment="EXISTENCE:mutant phenotype:GO:0005634 nucleus
[PMID:15522095]"
/experiment="EXISTENCE:mutant phenotype:GO:0030466 silent
mating-type cassette heterochromatin formation
[PMID:16908533|PMID:8582634]"
/experiment="EXISTENCE:mutant phenotype:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:15192094]"
/experiment="EXISTENCE:mutant phenotype:GO:0070911 global
genome nucleotide-excision repair [PMID:10601031]"
/note="DNA binding protein with possible
chromatin-reorganizing activity; involved in
transcriptional activation, gene silencing, and DNA
replication and repair"
/codon_start=1
/product="DNA-binding protein ABF1"
/protein_id="DAA09046.1"
/db_xref="SGD:S000001595"
/translation="MDKLVVNYYEYKHPIINKDLAIGAHGGKKFPTLGAWYDVINEYE
FQTRCPIILKNSHRNKHFTFACHLKNCPFKVLLSYAGNAASSETSSPSANNNTNPPGT
PDHIHHHSNNMNNEDNDNNNGSNNKVSNDSKLDFVTDDLEYHLANTHPDDTNDKVESR
SNEVNGNNDDDADANNIFKQQGVTIKNDTEDDSINKASIDRGLDDESGPTHGNDSGNH
RHNEEDDVHTQMTKNYSDVVNDEDINVAIANAVANVDSQSNNKHDGKDDDATNNNDGQ
DNNTNNDHNNNSNINNNNVGSHGISSHSPSSIRDTSMNLDVFNSATDDIPGPFVVTKI
EPYHSHPLEDNLSLGKFILTKIPKILQNDLKFDQILESSYNNSNHTVSKFKVSHYVEE
SGLLDILMQRYGLTAEDFEKRLLSQIARRITTYKARFVLKKKKMGEYNDLQPSSSSNN
NNNNDGELSGTNLRSNSIDYAKHQEISSAGTSSNTTKNVNNNKNDSNDDNNGNNNNDA
SNLMESVLDKTSSHRYQPKKMPSVNKWSKPDQITHSDVSMVGLDESNDGGNENVHPTL
AEVDAQEARETAQLAIDKINSYKRSIDDKNGDGHNNSSRNVVDENLINDMDSEDAHKS
KRQHLSDITLEERNEDDKLPHEVAEQLRLLSSHLKEVENLHQNNDDDVDDVMVDVDVE
SQYNKNTTHHNNHHSQPHHDEEDVAGLIGKADDEEDLSDENIQPELRGQ"
gene complement(228939..229880)
/gene="KTI12"
/locus_tag="YKL110C"
/gene_synonym="TOT4"
mRNA complement(228939..229880)
/gene="KTI12"
/locus_tag="YKL110C"
/gene_synonym="TOT4"
/product="Kti12p"
CDS complement(228939..229880)
/gene="KTI12"
/locus_tag="YKL110C"
/gene_synonym="TOT4"
/experiment="EXISTENCE:direct assay:GO:0003682 chromatin
binding [PMID:15772087]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:12139626]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:12139626]"
/experiment="EXISTENCE:genetic interaction:GO:0006357
regulation of transcription by RNA polymerase II
[PMID:15772087]"
/experiment="EXISTENCE:mutant phenotype:GO:0002098 tRNA
wobble uridine modification [PMID:18755837]"
/note="Protein that plays a role in modification of tRNA
wobble nucleosides; protein plays role in tRNA wobble
nucleoside modification with Elongator complex; involved
in sensitivity to G1 arrest induced by zymocin; interacts
with chromatin throughout the genome; also interacts with
Cdc19p"
/codon_start=1
/product="Kti12p"
/protein_id="DAA09047.1"
/db_xref="SGD:S000001593"
/translation="MPLVLFTGYPCSGKTTLAKHLVQLLQSKIDATPSLSKYSITYHS
DESLGIKHSDYITSQDERKLRSEIISAVKRDLSKNKIVIVDSLNYIKGFRYQLHCEVK
NLSTTFCVIQTLCPPETIFEWNKTSNPNPWEPELLNQLIQRYEEPNSSNRWDSPLFAI
LTPQDNITDYIDDICKVVFQTSKSAKNSGHNDPLSKGLQKPNSATVLKPASQSNFIQV
LDIETSKIIKTIMNHIKSLTSIGGVSNGTRVIVSEGITDINDDGCFFVDLPIGNVVTL
AQLQRLKRQFINFNKLRDIDQDRIGPLFADYLNKNLN"
gene 232227..233891
/gene="HAP4"
/locus_tag="YKL109W"
mRNA 232227..233891
/gene="HAP4"
/locus_tag="YKL109W"
/product="transcription factor HAP4"
CDS 232227..233891
/gene="HAP4"
/locus_tag="YKL109W"
/experiment="EXISTENCE:direct assay:GO:0016602
CCAAT-binding factor complex [PMID:2676721]"
/experiment="EXISTENCE:direct assay:GO:0061629 RNA
polymerase II-specific DNA-binding transcription factor
binding [PMID:11423663]"
/experiment="EXISTENCE:mutant phenotype:GO:0000436 carbon
catabolite activation of transcription from RNA polymerase
II promoter [PMID:2676721]"
/experiment="EXISTENCE:mutant phenotype:GO:0003713
transcription coactivator activity [PMID:2123465]"
/experiment="EXISTENCE:mutant phenotype:GO:0043457
regulation of cellular respiration [PMID:2676721]"
/experiment="EXISTENCE:physical interaction:GO:0061629 RNA
polymerase II-specific DNA-binding transcription factor
binding [PMID:11423663]"
/note="Transcription factor; subunit of the
heme-activated, glucose-repressed Hap2p/3p/4p/5p
CCAAT-binding complex, a transcriptional activator and
global regulator of respiratory gene expression; provides
the principal activation function of the complex; involved
in diauxic shift"
/codon_start=1
/product="transcription factor HAP4"
/protein_id="DAA09048.1"
/db_xref="SGD:S000001592"
/translation="MTAKTFLLQASASRPRSNHFKNEHNNIPLAPVPIAPNTNHHNNS
SLEFENDGSKKKKKSSLVVRTSKHWVLPPRPRPGRRSSSHNTLPANNTNNILNVGPNS
RNSSNNNNNNNIISNRKQASKEKRKIPRHIQTIDEKLINDSNYLAFLKFDDLENEKFH
SSASSISSPSYSSPSFSSYRNRKKSEFMDDESCTDVETIAAHNSLLTKNHHIDSSSNV
HAPPTKKSKLNDFDLLSLSSTSSSATPVPQLTKDLNMNLNFHKIPHKASFPDSPADFS
PADSVSLIRNHSLPTNLQVKDKIEDLNEIKFFNDFEKLEFFNKYAKVNTNNDVNENND
LWNSYLQSMDDTTGKNSGNYQQVDNDDNMSLLNLPILEETVSSGQDDKVEPDEEDIWN
YLPSSSSQQEDSSRALKKNTNSEKANIQAKNDETYLFLQDQDESADSHHHDELGSEIT
LADNKFSYLPPTLEELMEEQDCNNGRSFKNFMFSNDTGIDGSAGTDDDYTKVLKSKKI
STSKSNANLYDLNDNNNDATATNELDQSSFIDDLDEDVDFLKVQVF"
gene 234426..235787
/gene="SLD2"
/locus_tag="YKL108W"
/gene_synonym="DRC1"
mRNA 234426..235787
/gene="SLD2"
/locus_tag="YKL108W"
/gene_synonym="DRC1"
/product="Sld2p"
CDS 234426..235787
/gene="SLD2"
/locus_tag="YKL108W"
/gene_synonym="DRC1"
/experiment="EXISTENCE:direct assay:GO:0003688 DNA
replication origin binding [PMID:21109535]"
/experiment="EXISTENCE:direct assay:GO:0003697
single-stranded DNA binding [PMID:21109535]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0031261 DNA
replication preinitiation complex [PMID:20231317]"
/experiment="EXISTENCE:genetic interaction:GO:0006270 DNA
replication initiation [PMID:17167415|PMID:17167417]"
/experiment="EXISTENCE:genetic interaction:GO:0031261 DNA
replication preinitiation complex [PMID:20231317]"
/experiment="EXISTENCE:mutant phenotype:GO:0000727
double-strand break repair via break-induced replication
[PMID:20516198]"
/experiment="EXISTENCE:mutant phenotype:GO:0003688 DNA
replication origin binding [PMID:21109535]"
/experiment="EXISTENCE:mutant phenotype:GO:0003697
single-stranded DNA binding [PMID:21109535]"
/experiment="EXISTENCE:mutant phenotype:GO:0031333
negative regulation of protein-containing complex assembly
[PMID:24307213]"
/experiment="EXISTENCE:mutant phenotype:GO:0033314 mitotic
DNA replication checkpoint signaling [PMID:10097122]"
/experiment="EXISTENCE:mutant phenotype:GO:0071163 DNA
replication preinitiation complex assembly
[PMID:20231317]"
/note="Single-stranded DNA origin-binding and annealing
protein; required for initiation of DNA replication;
phosphorylated in S phase by cyclin-dependent kinases
(Cdks), promoting origin binding, DNA replication and
Dpb11p complex formation; component of the preloading
complex; binds the Mcm2-7p complex to prevent
inappropriate Mcm2-7p interaction with the GINS complex in
G1; required for S phase checkpoint; relative distribution
to the nucleus increases upon DNA replication stress"
/codon_start=1
/product="Sld2p"
/protein_id="DAA09049.1"
/db_xref="SGD:S000001591"
/translation="MYSFELDKLKIELKTWEHDFIDKNKREPTRDDIKSLRTVRQMYK
QYSTLKKKQSLQRQKVDTQESVELPAHKKDHDEVVEIGPTPQVYGKAISIFDMNLSPI
KPIYMTFTNNIDVNNDNSKTISNESSPRKTILLKSSPADRTLVAEPISSVKRQLNFQM
LNASSTRTPTSSPCKNRNGKLVEIKKCSPTINPPLESGKPSGYYGPNSPLKLDEENIH
LNISLNSSTKRRLQIAYPSLQKTPSKDQADISTSFSPSPLIRRPLTKSLIELAREHTE
IVKEFGVLQEEDIEEEEEGEEGENGYDEKNHEDDFGLEDELIRPKVVKDIFQEDDDND
DSQAREDTFIRKRPKRRKVIRRLRDNDPETETAGFERDVHKELVKLKRRKVAEFLGST
SQISDTEFEHDPEASSGVVSSEQKPTAKRKGRKKYNLVSNNFRRLKLPKKNRFSNGRW
GRR"
gene 236141..237070
/locus_tag="YKL107W"
mRNA 236141..237070
/locus_tag="YKL107W"
/product="putative short-chain dehydrogenase/reductase"
CDS 236141..237070
/locus_tag="YKL107W"
/experiment="EXISTENCE:direct assay:GO:0004029 aldehyde
dehydrogenase (NAD+) activity [PMID:31115629]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:31115629]"
/experiment="EXISTENCE:mutant phenotype:GO:1901426
response to furfural [PMID:31115629]"
/note="NADH-dependent aldehyde reductase; involved in the
detoxification of acetaldehyde, glycolaldehyde, furfural,
formaldehyde and propionaldehyde; localizes to the
endoplasmic reticulum; member of the classical short-chain
dehydrogenase/reductase (SDR) family"
/codon_start=1
/product="putative short-chain dehydrogenase/reductase"
/protein_id="DAA09050.1"
/db_xref="SGD:S000001590"
/translation="MFWKKDPTVSWERKNINDIDFSRFNVAIIGGTGGLGRAISRELA
QRNARVTVVGQTFRDEDLKDKINFVKADLSLVSECKRISHSDEIPYEELTHLIFTTGI
FASRQRQATSEGLEKDMAVSYLSRYIIFHDVAKRLGISRTKKDDLPKVFIAGFPGNGQ
VGDPDDLNSDEKKYSAYATHMNTVAANESLVIDAKDRYTNIDTFGLNPGLIKTNIRNN
LLGSDTYLSRITEWIISWTCQSAETYAKTICTLIASPAIESRSGTMFSNKGDAILPSP
GLTKDVVEKFMENSELLVEKALRNQSPFTSSNE"
gene complement(237147..237266)
/locus_tag="YKL106C-A"
mRNA complement(237147..237266)
/locus_tag="YKL106C-A"
/product="hypothetical protein"
CDS complement(237147..237266)
/locus_tag="YKL106C-A"
/note="hypothetical protein; identified by homology to
uncharacterized proteins in other fungi"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09051.1"
/db_xref="SGD:S000007616"
/translation="MPFPSILHLTIGRYASYDSNNHMRRRAKLMEAIFRIRTI"
gene 237536..238891
/gene="AAT1"
/locus_tag="YKL106W"
mRNA 237536..238891
/gene="AAT1"
/locus_tag="YKL106W"
/product="aspartate transaminase AAT1"
CDS 237536..238891
/gene="AAT1"
/locus_tag="YKL106W"
/EC_number="2.6.1.1"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion
[PMID:14576278|PMID:24769239|PMID:16823961|PMID:22010850]"
/experiment="EXISTENCE:mutant phenotype:GO:1901605
alpha-amino acid metabolic process [PMID:33397945]"
/note="Mitochondrial aspartate aminotransferase; catalyzes
the conversion of oxaloacetate to aspartate in aspartate
and asparagine biosynthesis"
/codon_start=1
/product="aspartate transaminase AAT1"
/protein_id="DAA09052.1"
/db_xref="SGD:S000001589"
/translation="MLRTRLTNCSLWRPYYTSSLSRVPRAPPDKVLGLSEHFKKVKNV
NKIDLTVGIYKDGWGKVTTFPSVAKAQKLIESHLELNKNLSYLPITGSKEFQENVMKF
LFKESCPQFGPFYLAHDRISFVQTLSGTGALAVAAKFLALFISRDIWIPDPSWANHKN
IFQNNGFENIYRYSYYKDGQIDIDGWIEQLKTFAYNNQQENNKNPPCIILHACCHNPT
GLDPTKEQWEKIIDTIYELKMVPIVDMAYQGLESGNLLKDAYLLRLCLNVNKYPNWSN
GIFLCQSFAKNMGLYGERVGSLSVITPATANNGKFNPLQQKNSLQQNIDSQLKKIVRG
MYSSPPGYGSRVVNVVLSDFKLKQQWFKDVDFMVQRLHHVRQEMFDRLGWPDLVNFAQ
QHGMFYYTRFSPKQVEILRNNYFVYLTGDGRLSLSGVNDSNVDYLCESLEAVSKMDKL
A"
gene complement(239185..242583)
/gene="SEG2"
/locus_tag="YKL105C"
mRNA complement(239185..242583)
/gene="SEG2"
/locus_tag="YKL105C"
/product="Seg2p"
CDS complement(239185..242583)
/gene="SEG2"
/locus_tag="YKL105C"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/note="Eisosome component; likely plays only a minor role
in eisosome assembly; shown to interact with Seg1p by
affinity purification and mass spec; SWAT-GFP and mCherry
fusion proteins localize to the cell periphery; similar to
A. gossypii SEG gene which is important for stabilizing
eisosomes; SEG2 has a paralog, SEG1, that arose from the
whole genome duplication"
/codon_start=1
/product="Seg2p"
/protein_id="DAA09053.1"
/db_xref="SGD:S000001588"
/translation="MIQESSPDALAAAAAIGNALSYNGRTVDKSKIPQYNQSFTSRTT
SIAGINRYTMLSNSRTNSRMLLMNGNVRQYSKRTSSLPNQGHKNTSNNSAGRRQHRAH
EDAETTFREFGGKQSSKVLNISSSTGQNSKSRTTSLGNSGSTIRTIKKYIPGPRGLMA
VEVPVEVEPPRYSLSNRSNQRGGRAYSLPTRNNKTSLMHRNKTTKKAGSQEKKSESGG
KSKNDYHGKVLSKMHTTSLKQRHNNVPLIPTTMNEETEQELQEDLHDPLEFKPMIISD
DENSFIEPSVLDRSIPKKDKSGLSGREKKEEIETLLKEVHSLEEKISNIEIAKLNEEE
REQSLILELRKVKLDEERRMELLKRELNIVKENADLEAQELKLIESKRKQHFHKGQEV
ASEVKSITIRQPTLSEPKPAYVPPEDVEKEPSTLSNQTQNIENAENIDSVDAEGNLVD
PILLGSLNNSNFHMNSDNEVRCIADSNSLTGSELSDYNYIEGSATDLRATAKTSVESE
IGGNQVGLKIPQDDDSEKQEERTKGKKSGLVDTNCFLVQKEDQEEALSDNEPESSEKF
PSTSGIENVKLEDETGSVMDKNNGPNNDKDDDDDKDNDNDDDDDKDDDVNDDDKDENV
DDDENVDDDDDDDDDDDDEYHDSYDVIMRDPVQIEQDISDVPSLKHPSEYSTETEDNK
KKEQNSENAEVSQSGTNMAKYLRGANPYLTNTSSDTFSLDSENVNSKSSTDTTRVAPD
LLKSSLQPQLRSDLKQSAVPSSTSSSIYSIETSPNIDSSTGKTASNTKTNSHGPPTSI
SKQKYDQSSSHQIPVMSPKRLDDKRKITNRSCLRTLRGSSNEATLSHNIVYPASDSSS
SPPYHSKKPSNPPSSGNLASHEASKCFPKAPQASTTSRRLPDHVPLYIDKNNSALYPK
EPPARKSSFEKERPAKDNLGFRSMSLREPLITKNATATAAENLDVEEKKEKGGHVSRK
SWTFGLPSPLKRRTSHSTHTTNETEIVNPMTNFKNKTNENDMPILANKKSCNNDDSSP
YTASSMNTNDVSEAGTEGHRFSLFGNKSQLSNRNISGGTATLESSNPDLPTALPLSVP
VTIIDKNGEIHKLHNDDAAIKDKSHDRHGHSKFGRKLKKIFGRK"
gene complement(243220..245373)
/gene="GFA1"
/locus_tag="YKL104C"
mRNA complement(243220..245373)
/gene="GFA1"
/locus_tag="YKL104C"
/product="glutamine--fructose-6-phosphate transaminase
(isomerizing) GFA1"
CDS complement(243220..245373)
/gene="GFA1"
/locus_tag="YKL104C"
/EC_number="2.6.1.16"
/experiment="EXISTENCE:direct assay:GO:0004360
glutamine-fructose-6-phosphate transaminase (isomerizing)
activity [PMID:2656689]"
/experiment="EXISTENCE:genetic interaction:GO:0034221
fungal-type cell wall chitin biosynthetic process
[PMID:11895440]"
/note="Glutamine-fructose-6-phosphate amidotransferase;
catalyzes the formation of glucosamine-6-P and glutamate
from fructose-6-P and glutamine in the first step of
chitin biosynthesis; GFA1 has a paralogous region,
comprising ORFs YMR084W-YMR085W, that arose from the whole
genome duplication"
/codon_start=1
/product="glutamine--fructose-6-phosphate transaminase
(isomerizing) GFA1"
/protein_id="DAA09054.1"
/db_xref="SGD:S000001587"
/translation="MCGIFGYCNYLVERSRGEIIDTLVDGLQRLEYRGYDSTGIAIDG
DEADSTFIYKQIGKVSALKEEITKQNPNRDVTFVSHCGIAHTRWATHGRPEQVNCHPQ
RSDPEDQFVVVHNGIITNFRELKTLLINKGYKFESDTDTECIAKLYLHLYNTNLQNGH
DLDFHELTKLVLLELEGSYGLLCKSCHYPNEVIATRKGSPLLIGVKSEKKLKVDFVDV
EFPEENAGQPEIPLKSNNKSFGLGPKKAREFEAGSQNANLLPIAANEFNLRHSQSRAF
LSEDGSPTPVEFFVSSDAASVVKHTKKVLFLEDDDLAHIYDGELHIHRSRREVGASMT
RSIQTLEMELAQIMKGPYDHFMQKEIYEQPESTFNTMRGRIDYENNKVILGGLKAWLP
VVRRARRLIMIACGTSYHSCLATRAIFEELSDIPVSVELASDFLDRKCPVFRDDVCVF
VSQSGETADTMLALNYCLERGALTVGIVNSVGSSISRVTHCGVHINAGPEIGVASTKA
YTSQYIALVMFALSLSDDRVSKIDRRIEIIQGLKLIPGQIKQVLKLEPRIKKLCATEL
KDQKSLLLLGRGYQFAAALEGALKIKEISYMHSEGVLAGELKHGVLALVDENLPIIAF
GTRDSLFPKVVSSIEQVTARKGHPIIICNENDEVWAQKSKSIDLQTLEVPQTVDCLQG
LINIIPLQLMSYWLAVNKGIDVDFPRNLAKSVTVE"
gene 245032..245286
/locus_tag="YKL104W-A"
mRNA 245032..245286
/locus_tag="YKL104W-A"
/product="hypothetical protein"
CDS 245032..245286
/locus_tag="YKL104W-A"
/note="Novel ORF identified by enrichment-based
proteomics"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAD54808.1"
/db_xref="SGD:S000303811"
/translation="MNDHKLVFWVRSLRVTVNLFWSTVSSPSSMRNTTMRDKSNVSVR
ILLSNLLFQSTHFTDLLIDESRISFVTIDSNTGGIIASIF"
gene complement(246138..247682)
/gene="APE1"
/locus_tag="YKL103C"
/gene_synonym="API"
/gene_synonym="LAP4"
/gene_synonym="YSC1"
mRNA complement(246138..247682)
/gene="APE1"
/locus_tag="YKL103C"
/gene_synonym="API"
/gene_synonym="LAP4"
/gene_synonym="YSC1"
/product="metalloaminopeptidase APE1"
CDS complement(246138..247682)
/gene="APE1"
/locus_tag="YKL103C"
/gene_synonym="API"
/gene_synonym="LAP4"
/gene_synonym="YSC1"
/EC_number="3.4.11.22"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:1400574]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0034270 Cvt complex
[PMID:9151668|PMID:9412464|PMID:20659891]"
/experiment="EXISTENCE:direct assay:GO:0070006
metalloaminopeptidase activity [PMID:3882418]"
/experiment="EXISTENCE:mutant phenotype:GO:0032258
cytoplasm to vacuole transport by the Cvt pathway
[PMID:18725539]"
/note="Vacuolar aminopeptidase yscI; zinc
metalloproteinase that belongs to peptidase family M18;
often used as marker in studies of autophagy and cytosol
to vacuole targeting (CVT) pathway; protein increases in
abundance and relative distribution to cytoplasmic foci
increases upon DNA replication stress; targeted to vacuole
via Vps10p-dependent endosomal vacuolar protein sorting
pathway and via CVT pathway"
/codon_start=1
/product="metalloaminopeptidase APE1"
/protein_id="DAA09055.1"
/db_xref="SGD:S000001586"
/translation="MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCI
LEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKF
YTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPY
GGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGP
FDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQ
MDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVT
LYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNP
NFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNS
RSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVY
DEFGEL"
gene complement(248062..248367)
/locus_tag="YKL102C"
mRNA complement(248062..248367)
/locus_tag="YKL102C"
/product="hypothetical protein"
CDS complement(248062..248367)
/locus_tag="YKL102C"
/note="hypothetical protein; conserved across S.
cerevisiae strains; deletion confers sensitivity to citric
acid; predicted protein would include a thiol-disulfide
oxidoreductase active site"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA80309.1"
/db_xref="SGD:S000001585"
/translation="MCALFAEVSSTAAASCSFGVLLCSGSNCGRLVGSERRKVLYVFN
VNVCKKMSSYYFLRHDNIVIPYLLRLLVSDKEASNKNPLLPFLMDKERSHHFVRNMN"
gene 248920..253476
/gene="HSL1"
/locus_tag="YKL101W"
/gene_synonym="ELM2"
/gene_synonym="NIK1"
mRNA 248920..253476
/gene="HSL1"
/locus_tag="YKL101W"
/gene_synonym="ELM2"
/gene_synonym="NIK1"
/product="protein kinase HSL1"
CDS 248920..253476
/gene="HSL1"
/locus_tag="YKL101W"
/gene_synonym="ELM2"
/gene_synonym="NIK1"
/EC_number="2.7.11.1"
/experiment="EXISTENCE:direct assay:GO:0000144 cellular
bud neck septin ring [PMID:27053666|PMID:9925642]"
/experiment="EXISTENCE:direct assay:GO:0004672 protein
kinase activity [PMID:9925642|PMID:16319894]"
/experiment="EXISTENCE:direct assay:GO:0004674 protein
serine/threonine kinase activity [PMID:11408575]"
/experiment="EXISTENCE:direct assay:GO:0005935 cellular
bud neck [PMID:10805747|PMID:15282802]"
/experiment="EXISTENCE:mutant phenotype:GO:0000086 G2/M
transition of mitotic cell cycle [PMID:10490630]"
/experiment="EXISTENCE:mutant phenotype:GO:0004674 protein
serine/threonine kinase activity [PMID:11408575]"
/experiment="EXISTENCE:mutant phenotype:GO:0030163 protein
catabolic process [PMID:23042131]"
/experiment="EXISTENCE:mutant phenotype:GO:0044879 mitotic
morphogenesis checkpoint signaling [PMID:9925642]"
/experiment="EXISTENCE:mutant phenotype:GO:0051726
regulation of cell cycle [PMID:8647431]"
/experiment="EXISTENCE:mutant phenotype:GO:1902935 protein
localization to septin ring [PMID:27053666]"
/experiment="EXISTENCE:physical interaction:GO:0000144
cellular bud neck septin ring [PMID:9925642]"
/note="Nim1p-related protein kinase; septin-binding kinase
that localizes to the bud neck septin ring and regulates
the morphogenesis checkpoint; phosphorylates Hsl7p and
cooperates with Elm1p to recruit Hsl7p to the mother-bud
neck, as a prerequisite for the subsequent recruitment,
phosphorylation, and degradation of Swe1p;
autophosphorylation enhances interactions with Hsl7p"
/codon_start=1
/product="protein kinase HSL1"
/protein_id="DAA09056.2"
/db_xref="SGD:S000001584"
/translation="MTGHVSKTSHVPKGRPSSLAKKAAKRAMAKVNSNPKRASGHLER
VVQSVNDATKRLSQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNME
TGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYG
IEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIH
YFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCG
SPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQM
PSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARG
KSNSDLHLLNNVSPSIVTLHSKGEIDESILRSLQILWHGVSRELITAKLLQKPMSEEK
LFYSLLLQYKQRHSISLSSSSENKKSATESSVNEPRIEYASKTANNTGLRSENNDVKT
LHSLEIHSEDTSTVNQNNAITGVNTEINAPVLAQKSQFSINTLSQPESDKAEAEAVTL
PPAIPIFNASSSRIFRNSYTSISSRSRRSLRLSNSRLSLSASTSRETVHDNEMPLPQL
PKSPSRYSLSRRAIHASPSTKSIHKSLSRKNIAATVAARRTLQNSASKRSLYSLQSIS
KRSLNLNDLLVFDDPLPSKKPASENVNKSEPHSLESDSDFEILCDQILFGNALDRILE
EEEDNEKERDTQRQRQNDTKSSADTFTISGVSTNKENEGPEYPTKIEKNQFNMSYKPS
ENMSGLSSFPIFEKENTLSSSYLEEQKPKRAALSDITNSFNKMNKQEGMRIEKKIQRE
QLQKKNDRPSPLKPIQHQELRVNSLPNDQGKPSLSLDPRRNISQPVNSKVESLLQGLK
FKKEPASHWTHERGSLFMSEHVEDEKPVKASDVSIESSYVPLTTVATSSRDPSVLAES
STIQKPMLSLPSSFLNTSMTFKNLSQILADDGDDKHLSVPQNQSRSVAMSHPLRKQSA
KISLTPRSNLNANLSVKRNQGSPGSYLSNDLDGISDMTFAMEIPTNTFTAQAIQLMNN
DTDNNKINTSPKASSFTKEKVIKSAAYISKEKEPDNSDTNYIPDYTIPNTYDEKAINI
FEDAPSDEGSLNTSSSESDSRASVHRKAVSIDTMATTNVLTPATNVRVSLYWNNNSSG
IPRETTEEILSKLRLSPENPSNTHMQKRFSSTRGSRDSNALGISQSLQSMFKDLEEDQ
DGHTSQADILESSMSYSKRRPSEESVNPKQRVTMLFDEEEEESKKVGGGKIKEEHTKL
DNKISEESSQLVLPVVEKKENANNTENNYSKIPKPSTIKVTKDTAMESNTQTHTKKPI
LKSVQNVEVEEAPSSDKKNWFVKLFQNFSSHNNATKASKNHVTNISFDDAHMLTLNEF
NKNSIDYQLKNLDHKFGRKVVEYDCKFVKGNFKFKIKITSTPNASTVITVKKRSKHSN
TSSNKAFEKFNDDVERVIRNAGRS"
gene complement(253697..255460)
/gene="YPF1"
/locus_tag="YKL100C"
mRNA complement(253697..255460)
/gene="YPF1"
/locus_tag="YKL100C"
/product="aspartic endopeptidase"
CDS complement(253697..255460)
/gene="YPF1"
/locus_tag="YKL100C"
/experiment="EXISTENCE:direct assay:GO:1990578 perinuclear
endoplasmic reticulum membrane [PMID:25454947]"
/experiment="EXISTENCE:mutant phenotype:GO:0009267
cellular response to starvation [PMID:25454947]"
/experiment="EXISTENCE:mutant phenotype:GO:0042500
aspartic endopeptidase activity, intramembrane cleaving
[PMID:25454947]"
/experiment="EXISTENCE:mutant phenotype:GO:0051603
proteolysis involved in protein catabolic process
[PMID:25454947]"
/note="Intramembrane aspartyl protease of the perinuclear
ER membrane; acts in a branch of ER-associated degradation
(ERAD) that degrades functional proteins rather than
misfolded proteins; regulates abundance of high-affinity
plasma membrane transporters, such as Ctr1p and Zrt1p,
during the starvation response; has a presenilin fold;
member of the GxGD family of intramembrane proteases;
closest human homolog is signal peptide peptidase (SPP)"
/codon_start=1
/product="aspartic endopeptidase"
/protein_id="DAA09057.1"
/db_xref="SGD:S000001583"
/translation="MDKYLNSFVDHLSEWSSRAFRNNSSSANQSASNKELEQVFEQIN
AIVENHNNKLTTAFDKISYRVAHKITHLVESHSLVFNYATLVLIASALVVIGSFTSIS
SIPFTALPPTREHSLFDPTDFDVDHDCHVIYRENDEDKKKKKKSKRFFDMMDEKHAII
LPLTSGCTLLALYFVIKKLHLNWLKYVVKILNFNITLLNIPAGTFVYSYFLNSLFRNL
SHLASWNPLVVLPRYRVTIADDNEDLNKIGGFVTNLNYKDGLTNSVVHKKTLDEIEKD
HWMKHFYRRELVEPKDIKSKRQISNMYLNSALIVSFVLSIVSTVYFYLSPNDWLISNA
VSMNMAIWSIAQLKLKNLKSGALILIALFFYDICFVFGTDVMVTVATNLDIPVKLSLP
VKFNTAQNNFNFSILGLGDIALPGMFIAMCYKYDIWKWHLDHDDTEFHFLNWSYVGKY
FITAMVSYVASLVSAMVSLSIFNTAQPALLYIVPSLLISTILVACWNKDFKQFWNFQY
DTIEVDKSLKKAIEKKENSITYSTFILSEYYNDADKYALLGDDVNENFDDDEEFVQEE
DLSDSSEEELSEEDLLDDESS"
gene complement(255720..256472)
/gene="UTP11"
/locus_tag="YKL099C"
mRNA complement(255720..256472)
/gene="UTP11"
/locus_tag="YKL099C"
/product="rRNA-processing protein UTP11"
CDS complement(255720..256472)
/gene="UTP11"
/locus_tag="YKL099C"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:12068309]"
/experiment="EXISTENCE:direct assay:GO:0032040
small-subunit processome [PMID:12068309]"
/experiment="EXISTENCE:mutant phenotype:GO:0000447
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from
5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15489292]"
/experiment="EXISTENCE:mutant phenotype:GO:0000472
endonucleolytic cleavage to generate mature 5'-end of
SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
[PMID:15489292]"
/experiment="EXISTENCE:mutant phenotype:GO:0000480
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA
transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
[PMID:15489292]"
/note="Subunit of U3-containing Small Subunit (SSU)
processome complex; involved in production of 18S rRNA and
assembly of small ribosomal subunit"
/codon_start=1
/product="rRNA-processing protein UTP11"
/protein_id="DAA09058.1"
/db_xref="SGD:S000001582"
/translation="MAKLVHDVQKKQHRERSQLTSRSRYGFLEKHKDYVKRAQDFHRK
QSTLKVLREKAKERNPDEYYHAMHSRKTDAKGLLISSRHGDEEDESLSMDQVKLLKTQ
DSNYVRTLRQIELKKLEKGAKQLMFKSSGNHTIFVDSREKMNEFTPEKFFNTTSEMVN
RSENRLTKDQLAQDISNNRNASSIMPKESLDKKKLKKFKQVKQHLQRETQLKQVQQRM
DAQRELLKKGSKKKIVDSSGKISFKWKKQRKR"
gene 256770..257843
/gene="MTC2"
/locus_tag="YKL098W"
mRNA 256770..257843
/gene="MTC2"
/locus_tag="YKL098W"
/product="Mtc2p"
CDS 256770..257843
/gene="MTC2"
/locus_tag="YKL098W"
/note="hypothetical protein; mtc2 is synthetically sick
with cdc13-1"
/codon_start=1
/product="Mtc2p"
/protein_id="DAA09059.1"
/db_xref="SGD:S000001581"
/translation="MGDHNLPDFQTCLKFSVTAKKSFLCMYRDSVSKEKLASSMPSTC
DIQLKRAINDAYPGGGIKVTVLNSTTASLDSLATTHVKEFEIVIIPDINSLLQPDQAK
LVKIMRDCTVAIEKAQSTRIFIGVVHWNNPVQPSGAAKDGDEAGKPAPKTRIFLPTSF
RMGAWLKHKFWFACAPPYLDFESSTESSINTRANNSIGMAEEEKQEPESKRSIILNEE
ANLNDVFVGSTVRRYILDIMVHLRTHRLTYNAKAGGVYTNSLDDVVLLSRLIGLHSGK
MFVSPSHVKEASRWYFPMHLELVQRSSMDSSLLYGSDPNLVDEMLEKLAKIKCEEVNE
FENPLFLESLVVKNVLSKVVPPV"
gene complement(258503..258913)
/locus_tag="YKL097C"
mRNA complement(258503..258913)
/locus_tag="YKL097C"
/product="hypothetical protein"
CDS complement(258503..258913)
/locus_tag="YKL097C"
/note="hypothetical protein; conserved across S.
cerevisiae strains; not conserved in closely related
Saccharomyces species"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA80310.1"
/db_xref="SGD:S000001580"
/translation="MFLFTFTILESEKLIIWPVPAVVLGVMAPKRAYSTPFGPWPGPA
ECLWNCPSELRQFSSCCLPLPKLRPPRPTFASLWRVVAAIAALFQVPWRRKTGVGKAI
FCIGCCCLAYQWRRTRYFAYKIMTGTCFMTDLAP"
gene complement(259073..259222)
/locus_tag="YKL096C-B"
mRNA complement(259073..259222)
/locus_tag="YKL096C-B"
/product="hypothetical protein"
CDS complement(259073..259222)
/locus_tag="YKL096C-B"
/note="hypothetical protein; identified by gene-trapping,
microarray-based expression analysis, and genome-wide
homology searching"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09060.1"
/db_xref="SGD:S000028667"
/translation="MKLFILDYEKKRTKIGKGMARRELKMMNKKPDLYTIIVSYFSIF
SLFFF"
gene 259253..259531
/gene="CWP2"
/locus_tag="YKL096W-A"
/gene_synonym="LPR1"
/gene_synonym="YKL097W-A"
mRNA 259253..259531
/gene="CWP2"
/locus_tag="YKL096W-A"
/gene_synonym="LPR1"
/gene_synonym="YKL097W-A"
/product="Cwp2p"
CDS 259253..259531
/gene="CWP2"
/locus_tag="YKL096W-A"
/gene_synonym="LPR1"
/gene_synonym="YKL097W-A"
/experiment="EXISTENCE:direct assay:GO:0005199 structural
constituent of cell wall [PMID:7768807]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
cell wall [PMID:11956747]"
/experiment="EXISTENCE:direct assay:GO:0031505 fungal-type
cell wall organization [PMID:7768807]"
/experiment="EXISTENCE:mutant phenotype:GO:0031505
fungal-type cell wall organization
[PMID:7768807|PMID:31537451]"
/note="Covalently linked cell wall mannoprotein; major
constituent of the cell wall; plays a role in stabilizing
the cell wall; involved in low pH resistance; precursor is
GPI-anchored"
/codon_start=1
/product="Cwp2p"
/protein_id="DAA09061.1"
/db_xref="SGD:S000001956"
/translation="MQFSTVASVAFVALANFVAAESAAAISQITDGQIQATTTATTEA
TTTAAPSSTVETVSPSSTETISQQTENGAAKAAVGMGAGALAAAAMLL"
gene 261132..261851
/gene="CWP1"
/locus_tag="YKL096W"
/gene_synonym="YJU1"
mRNA 261132..261851
/gene="CWP1"
/locus_tag="YKL096W"
/gene_synonym="YJU1"
/product="Cwp1p"
CDS 261132..261851
/gene="CWP1"
/locus_tag="YKL096W"
/gene_synonym="YJU1"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005199 structural
constituent of cell wall [PMID:7768807]"
/experiment="EXISTENCE:direct assay:GO:0005628 prospore
membrane [PMID:18756268]"
/experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
cell wall [PMID:15781460|PMID:9335273]"
/experiment="EXISTENCE:direct assay:GO:0031505 fungal-type
cell wall organization [PMID:7768807]"
/experiment="EXISTENCE:direct assay:GO:0071597 cellular
birth scar [PMID:16672383]"
/experiment="EXISTENCE:genetic interaction:GO:0032120
ascospore-type prospore membrane formation
[PMID:18756268]"
/experiment="EXISTENCE:mutant phenotype:GO:0031505
fungal-type cell wall organization [PMID:7768807]"
/note="Cell wall mannoprotein that localizes to birth
scars of daughter cells; linked to beta-1,3- and
beta-1,6-glucan heteropolymer through phosphodiester bond;
required for propionic acid resistance; targeted to
vacuole via AP-3 pathway"
/codon_start=1
/product="Cwp1p"
/protein_id="DAA09062.1"
/db_xref="SGD:S000001579"
/translation="MKFSTALSVALFALAKMVIADSEEFGLVSIRSGSDLQYLSVYSD
NGTLKLGSGSGSFEATITDDGKLKFDDDKYAVVNEDGSFKEGSESDAATGFSIKDGHL
NYKSSSGFYAIKDGSSYIFSSKQSDDATGVAIRPTSKSGSVAADFSPSDSSSSSSASA
SSASASSSTKHSSSIESVETSTTVETSSASSPTASVISQITDGQIQAPNTVYEQTENA
GAKAAVGMGAGALAVAAAYLL"
gene 262277..263113
/gene="YJU2"
/locus_tag="YKL095W"
/gene_synonym="CWC16"
mRNA 262277..263113
/gene="YJU2"
/locus_tag="YKL095W"
/gene_synonym="CWC16"
/product="mRNA splicing protein YJU2"
CDS 262277..263113
/gene="YJU2"
/locus_tag="YKL095W"
/gene_synonym="CWC16"
/experiment="EXISTENCE:direct assay:GO:0000349 generation
of catalytic spliceosome for first transesterification
step [PMID:17515604]"
/experiment="EXISTENCE:direct assay:GO:0000384 first
spliceosomal transesterification activity [PMID:17515604]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0071006 U2-type
catalytic step 1 spliceosome [PMID:17515604]"
/note="Essential protein required for pre-mRNA splicing;
associates transiently with the spliceosomal NTC
('nineteen complex') and acts after Prp2p to promote the
first catalytic reaction of splicing"
/codon_start=1
/product="mRNA splicing protein YJU2"
/protein_id="DAA09063.1"
/db_xref="SGD:S000001578"
/translation="MSERKAINKYYPPDYNPLEAEKLSRKMAKKLKTMNKSHASIRLM
TPFSMRCLECNEYIPKSRKFNGKKELLKEKYLDSIKIYRLTISCPRCANSIAFRTDPG
NSDYVMEVGGVRNYVPQKPNDDLNAKTAVESIDETLQRLVREKEMEQNEKMGIKEQAD
DKMDLLEKRLAKIQQEQEDDEELENLRKKNLEMSQRAEMINRSKHAQQEKAVTTDDLD
NLVDQVFDNHRQRTNKPGNNNDEKRTPLFNPTSTKGKIQKKSSVRTNPLGIVIKRGKS
LK"
gene 263349..264290
/gene="YJU3"
/locus_tag="YKL094W"
mRNA 263349..264290
/gene="YJU3"
/locus_tag="YKL094W"
/product="acylglycerol lipase"
CDS 263349..264290
/gene="YJU3"
/locus_tag="YKL094W"
/EC_number="3.1.1.23"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005741
mitochondrial outer membrane [PMID:16407407]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005811 lipid
droplet [PMID:10515935|PMID:20554061|PMID:24868093]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:16622836]"
/experiment="EXISTENCE:direct assay:GO:0016020 membrane
[PMID:20554061]"
/experiment="EXISTENCE:direct assay:GO:0017171 serine
hydrolase activity [PMID:14645503]"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/experiment="EXISTENCE:mutant phenotype:GO:0006641
triglyceride metabolic process [PMID:20554061]"
/experiment="EXISTENCE:mutant phenotype:GO:0047372
acylglycerol lipase activity [PMID:20554061]"
/note="Monoglyceride lipase (MGL) that hydrolyzes fatty
acid ethyl esters; required for removal of toxic
metabolites in ethanol producing yeast cells; localizes to
lipid particles and membranes; member of the eukaryotic
serine hydrolase family; functional ortholog of mammalian
MGL"
/codon_start=1
/product="acylglycerol lipase"
/protein_id="DAA09064.1"
/db_xref="SGD:S000001577"
/translation="MAPYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVL
LIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF
VEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMY
NKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDF
MQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLY
PGARHSIFSLETDKVFNTVFNDMKQWLDKHTTTEAKP"
gene 264789..265808
/gene="MBR1"
/locus_tag="YKL093W"
mRNA 264789..265808
/gene="MBR1"
/locus_tag="YKL093W"
/product="Mbr1p"
CDS 264789..265808
/gene="MBR1"
/locus_tag="YKL093W"
/experiment="EXISTENCE:mutant phenotype:GO:0009060 aerobic
respiration [PMID:8208248]"
/note="Protein involved in mitochondrial functions and
stress response; overexpression suppresses growth defects
of hap2, hap3, and hap4 mutants; MBR1 has a paralog, ISF1,
that arose from the whole genome duplication"
/codon_start=1
/product="Mbr1p"
/protein_id="DAA09065.1"
/db_xref="SGD:S000001576"
/translation="MRMEKTTDKPLSAGDMNDEYSRGPIDDIDCLNFFERAVQDPCCE
ACDTEDADEELRAKLSSFNFQPDSSPCNAKCQQTLNPLCKIDEALPAESELAPSRNGS
VSEANSDTNSIASTVHDPVDSKYGGMPSLRKAKTTSYFTSSSSNNTTMRNPLKKCNTN
INGLLVNGRSSSSSRQSIPELFSGACTKKKNNVLLKSETPNSEFSSNSLQHCNSRSFS
LPRSRSRSSAIAIPTHLYGLEKYVSPGLDTLTADPEESIERFSNNRPREISSCCPNDT
GDTSSSLSHSNTSSSLNFPLGTNTNQFHQPRQPVQQQQSSKPNFGAGRKKSFIEMSLA
SSFAG"
gene complement(266145..269459)
/gene="BUD2"
/locus_tag="YKL092C"
/gene_synonym="CLA2"
/gene_synonym="ERC25"
mRNA complement(266145..269459)
/gene="BUD2"
/locus_tag="YKL092C"
/gene_synonym="CLA2"
/gene_synonym="ERC25"
/product="GTPase-activating protein BUD2"
CDS complement(266145..269459)
/gene="BUD2"
/locus_tag="YKL092C"
/gene_synonym="CLA2"
/gene_synonym="ERC25"
/experiment="EXISTENCE:direct assay:GO:0000131 incipient
cellular bud site [PMID:10444589]"
/experiment="EXISTENCE:direct assay:GO:0005096 GTPase
activator activity [PMID:8371782]"
/experiment="EXISTENCE:direct assay:GO:0005628 prospore
membrane [PMID:24390141]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005935 cellular
bud neck [PMID:10444589|PMID:14562095]"
/experiment="EXISTENCE:mutant phenotype:GO:0007120 axial
cellular bud site selection [PMID:2065354|PMID:22558355]"
/experiment="EXISTENCE:mutant phenotype:GO:0007121 bipolar
cellular bud site selection [PMID:2065354]"
/experiment="EXISTENCE:mutant phenotype:GO:0007163
establishment or maintenance of cell polarity
[PMID:23783029]"
/experiment="EXISTENCE:mutant phenotype:GO:0030447
filamentous growth [PMID:15645503]"
/experiment="EXISTENCE:mutant phenotype:GO:0031578 mitotic
spindle orientation checkpoint signaling [PMID:22558355]"
/experiment="EXISTENCE:mutant phenotype:GO:0036267
invasive filamentous growth [PMID:23783029]"
/note="GTPase activating factor for Rsr1p/Bud1p; plays a
role in spindle position checkpoint distinct from its role
in bud site selection; required for both axial and bipolar
budding patterns; mutants exhibit random budding in all
cell types; contains two PH-like domains"
/codon_start=1
/product="GTPase-activating protein BUD2"
/protein_id="DAA09066.1"
/db_xref="SGD:S000001575"
/translation="MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLN
DWKTHYLQITSTGALTHSIDELTADSTNIQPIIKHLQQCRIEIIKDKHSSFKDINANC
NFIIQVNTSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSK
KMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNG
MLDLLLQSDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFR
IENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKIS
NSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSNSSNPFWREEFQF
NELLRLTNSYLEIKQLFHDLNNKKRLRLIGKIKITQEIINDTRYNKETRLPIMDVDNK
NFQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQ
TSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSIL
TKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYK
RLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLR
FFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFID
KRHNDLLDYIDKMTQKKLDFNSKILNLSSTISRPKLAIEQTMLDDLPQIPYLLDKNLR
ETEFVNLIVNFSQEDMTKMEKYNHMDNGGKGELIEEEGLLSGSSLNLSVDKKDLDSPI
EVKPEIGELEFEKITENNTEIFGDDLMNLLKSDDVGSRSRDLDNGANSGIKFNSIIPK
AEEEKHAMKELEQESCLLYNRINHIRKRLSGYECASSTLFEDKKYSISLSHKIFYEEI
KEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDSYCKFLTIDVSDENPKS
SNKTSVHGTSSENGAKDDYLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNS
RKLTRWFKKKKETGGS"
gene complement(269718..270650)
/locus_tag="YKL091C"
/gene_synonym="SFH1"
mRNA complement(269718..270650)
/locus_tag="YKL091C"
/gene_synonym="SFH1"
/product="phosphatidylinositol/phosphatidylcholine-binding
protein"
CDS complement(269718..270650)
/locus_tag="YKL091C"
/gene_synonym="SFH1"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:12869188]"
/experiment="EXISTENCE:direct assay:GO:0031210
phosphatidylcholine binding [PMID:18243114]"
/experiment="EXISTENCE:direct assay:GO:0035091
phosphatidylinositol binding [PMID:18243114]"
/note="Putative phosphatidylinositol/phosphatidylcholine
transfer protein; possibly involved in lipid metabolism;
localizes to the nucleus; contains a CRAL/TRIO domain and
binds several lipids in a large-scale study; YKL091C has a
paralog, SEC14, that arose from the whole genome
duplication"
/codon_start=1
/product="phosphatidylinositol/phosphatidylcholine-binding
protein"
/protein_id="DAA09067.1"
/db_xref="SGD:S000001574"
/translation="MTTSILDTYPQICSPNALPGTPGNLTKEQEEALLQFRSILLEKN
YKERLDDSTLLRFLRARKFDINASVEMFVETERWREEYGANTIIEDYENNKEAEDKER
IKLAKMYPQYYHHVDKDGRPLYFEELGGINLKKMYKITTEKQMLRNLVKEYELFATYR
VPACSRRAGYLIETSCTVLDLKGISLSNAYHVLSYIKDVADISQNYYPERMGKFYIIH
SPFGFSTMFKMVKPFLDPVTVSKIFILGSSYKKELLKQIPIENLPVKYGGTSVLHNPN
DKFYYSDIGPWRDPRYIGPEGEIPNIFGKFTVTS"
gene 271878..273209
/gene="CUE2"
/locus_tag="YKL090W"
mRNA 271878..273209
/gene="CUE2"
/locus_tag="YKL090W"
/product="Cue2p"
CDS 271878..273209
/gene="CUE2"
/locus_tag="YKL090W"
/experiment="EXISTENCE:direct assay:GO:0004519
endonuclease activity [PMID:31219035]"
/experiment="EXISTENCE:direct assay:GO:0004521 RNA
endonuclease activity [PMID:31219035]"
/experiment="EXISTENCE:direct assay:GO:0022626 cytosolic
ribosome [PMID:31219035]"
/experiment="EXISTENCE:direct assay:GO:0043130 ubiquitin
binding [PMID:12628920|PMID:12787503]"
/experiment="EXISTENCE:direct assay:GO:0070966
nuclear-transcribed mRNA catabolic process, no-go decay
[PMID:31219035]"
/note="Ubiquitin-binding endonuclease involved in mRNA
decay; recruited to stalled ribosomes to promote breakdown
of transcript body of nuclear-transcribed mRNA with stalls
in translation elongation; cleaves mRNA within A site of
colliding ribosome; has two CUE domains that bind
ubiquitin, which may facilitate intramolecular
monoubiquitination"
/codon_start=1
/product="Cue2p"
/protein_id="DAA09068.1"
/db_xref="SGD:S000001573"
/translation="MSMDNNDDHESKLSILMDMFPAISKSKLQVHLLENNNDLDLTIG
LLLKENDDKSTVDNELHQLYDMFPQLDCSVIKDQFVINEKSVESTISDLLNYETLQKL
KDNQANSPDSVKRNEKKNNWESTNDHIESIIKFTDAPKNIAQEYLAENGFDTVKAIIK
IILDYYDKRDFKKDVDTFKVKRSPNTTVRGGRVQSSTGLAHVLKKGKESANVAQESLK
RPRSYKHSLDSPQMVELNELVADNRDLKAINHEFLQKCLQFYDGDVVKVLNISSLLIE
DDKNITKTWNFDEGFTLTSRDNCKQHLPKFSTPQISRRNEVGNTYKLPLHDKETPEGA
VPVINNLFQTYRLDFHGFLPSEAVSTLKLALNKWWSKEVAERELNSHNINSYGSKVQF
VSPLIVVTGRGIHSIGGISKVRLQVKSFLEKNHYIFWEESSYFRIEGKKKK"
gene 273394..275043
/gene="MIF2"
/locus_tag="YKL089W"
mRNA 273394..275043
/gene="MIF2"
/locus_tag="YKL089W"
/product="Mif2p"
CDS 273394..275043
/gene="MIF2"
/locus_tag="YKL089W"
/experiment="EXISTENCE:direct assay:GO:0000779 condensed
chromosome, centromeric region [PMID:9407032]"
/experiment="EXISTENCE:direct assay:GO:0019237 centromeric
DNA binding [PMID:9407032|PMID:18701705]"
/experiment="EXISTENCE:direct assay:GO:0044877
protein-containing complex binding [PMID:14581449]"
/experiment="EXISTENCE:genetic interaction:GO:0007059
chromosome segregation [PMID:22561346]"
/experiment="EXISTENCE:mutant phenotype:GO:0007052 mitotic
spindle organization [PMID:8408221]"
/experiment="EXISTENCE:mutant phenotype:GO:0007059
chromosome segregation [PMID:8408221]"
/experiment="EXISTENCE:mutant phenotype:GO:0051382
kinetochore assembly [PMID:18701705]"
/note="Centromeric CDEIII region binding protein;
nucleates kinetochore assembly; required for the
structural integrity of elongating spindles; copurifies
with subunits of the MIND complex and centromeric
nucleosome components (Cse4p and histones H2A, H2B, and
H4); phosphorylated by Ipl1p; orthologous to human
centromere constitutive-associated network (CCAN) subunit
CENP-C and fission yeast cnp3; localizes to the
kinetochore"
/codon_start=1
/product="Mif2p"
/protein_id="DAA09069.1"
/db_xref="SGD:S000001572"
/translation="MDYMKLGLKSRKTGIDVKQDIPKDEYSMENIDDFFKDDETSLIS
MRRKSRRKSSLFLPSTLNGDTKNVLPPFLQSYKSQDDEVVQSPSGKGDGSRRSSLLSH
QSNFLSPANDFEPIEEEPEQEENDIRGNDFATPITQKLSKPTYKRKYSTRYSLDTSES
PSVRLTPDRITNKNVYSDVPDLVADEDDDDRVNTSLNTSDNALLEDELEDDGFIPESE
EDGDYIESDSSLDSGSDSASDSDGDNTYQEVEEEAEVNTNDNEDDYIRRQASDVVRTD
SIIDRNGLRKSTRVKVAPLQYWRNEKIVYKRKSNKPVLDIDKIVTYDESEDEEEILAA
QRRKKQKKKPTPTRPYNYVPTGRPRGRPKKDPNAKENLIPEDPNEDIIERIESGGIEN
GEWLKHGILEANVKISDTKEETKDEIIAFAPNLSQTEQVKDTKDENFALEIMFDKHKE
YFASGILKLPAISGQKKLSNSFRTYITFHVIQGIVEVTVCKNKFLSVKGSTFQIPAFN
EYAIANRGNDEAKMFFVQVTVSEDANDDNDKELDSTFDTFG"
gene 275283..276998
/gene="CAB3"
/locus_tag="YKL088W"
mRNA 275283..276998
/gene="CAB3"
/locus_tag="YKL088W"
/product="phosphopantothenoylcysteine decarboxylase
complex subunit CAB3"
CDS 275283..276998
/gene="CAB3"
/locus_tag="YKL088W"
/experiment="EXISTENCE:direct assay:GO:0004633
phosphopantothenoylcysteine decarboxylase activity
[PMID:19915539]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095|PMID:14690591]"
/experiment="EXISTENCE:direct assay:GO:0071513
phosphopantothenoylcysteine decarboxylase complex
[PMID:19915539]"
/experiment="EXISTENCE:direct assay:GO:1990143
CoA-synthesizing protein complex [PMID:23789928]"
/experiment="EXISTENCE:genetic interaction:GO:0015937
coenzyme A biosynthetic process
[PMID:19266201|PMID:19915539]"
/experiment="EXISTENCE:mutant phenotype:GO:0004633
phosphopantothenoylcysteine decarboxylase activity
[PMID:19915539]"
/note="Subunit of PPCDC and CoA-SPC complexes involved in
CoA biosynthesis; subunits of the
phosphopantothenoylcysteine decarboxylase (PPCDC) complex
are: Cab3p, Sis2p, Vhs3p, while the subunits of the
CoA-synthesizing protein complex (CoA-SPC) are: Cab2p,
Cab3p, Cab4p, and Cab5p as well as Sis2p and Vhs3p; null
mutant lethality is complemented by E. coli coaBC"
/codon_start=1
/product="phosphopantothenoylcysteine decarboxylase
complex subunit CAB3"
/protein_id="DAA09070.1"
/db_xref="SGD:S000001571"
/translation="MTDEKVNSDQNMNGKQGVNLISSLPTTQVPVSILTNKERRKSIH
DESNFERSDSHEDQSKSNSNRRNIYKNDYSTNLRDFSFANLKQNSERNKDGHEIQINT
SMPANTNGQQKRFSPSLPSAVSFTVPEVERLPYHRYSISNKPGKQQQQQEQLQQNQQQ
EEQQKAQLQEQNQRAKQQEEVKQIQEQVQKKQTERQQLIDEKERIANAIFKENTTNDG
TDIRKHSVSSGTSNSEDEVDSPSMEKNSIVHMPGDFIYFNPKSNASKPITAKAAPLSA
NNSTHKNKEVITAPTGPRVPFTEFFQKEDDKKFHILIGATGSVATIKVPLIIDKLFKI
YGPEKISIQLIVTKPAEHFLKGLKMSTHVKIWREEDAWVFDAVNKNDTSLSLNLILHH
ELRKWADIFLIAPLSANTLAKLANGICNNLLTSVMRDWSPLTPVLIAPAMNTFMYINP
MTKKHLTSLVQDYPFIQVLKPVEKVLICGDIGMGGMREWTDIVEIVRRRINEIRKARD
EETGDKEQEQEEQEGADNEDDDDEDDEEDEEDEEEEEALNETASDESNDEEDEEDEED
VKTEV"
gene complement(277189..277863)
/gene="CYT2"
/locus_tag="YKL087C"
mRNA complement(277189..277863)
/gene="CYT2"
/locus_tag="YKL087C"
/product="cytochrome c1 heme lyase CYT2"
CDS complement(277189..277863)
/gene="CYT2"
/locus_tag="YKL087C"
/EC_number="4.4.1.17"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005758
mitochondrial intermembrane space [PMID:7559417]"
/experiment="EXISTENCE:mutant phenotype:GO:0004408
holocytochrome-c synthase activity [PMID:1499554]"
/experiment="EXISTENCE:mutant phenotype:GO:0018063
cytochrome c-heme linkage [PMID:1499554]"
/note="Cytochrome c1 heme lyase; involved in maturation of
cytochrome c1, which is a subunit of the mitochondrial
ubiquinol-cytochrome-c reductase; links heme covalently to
apocytochrome c1; human homolog HCCS can complement yeast
cyt2 null mutant"
/codon_start=1
/product="cytochrome c1 heme lyase CYT2"
/protein_id="DAA09071.1"
/db_xref="SGD:S000001570"
/translation="MMSSDQQGKCPVDEETKKLWLREHGNEAHPGATAPGNQLECSAN
PQDNDKTPEYHTTVDLSQSREVSTIPRTNSDRNWIYPSEKQFYEAMMKKNWDPNSDDM
KVVVPLHNSINERVWNYIKSWEDKQGGEACGGIKLTNFKGDSKKLTPRAWFRSRILHL
AKPFDRHDWQIDRCGKTVDYVIDFYSTDLNDANSQQQPLIYLDVRPKLNSFEGFRLRF
WKSLGF"
gene 278281..278664
/gene="SRX1"
/locus_tag="YKL086W"
mRNA 278281..278664
/gene="SRX1"
/locus_tag="YKL086W"
/product="sulfiredoxin"
CDS 278281..278664
/gene="SRX1"
/locus_tag="YKL086W"
/EC_number="1.8.98.2"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0032542
sulfiredoxin activity [PMID:14586471]"
/experiment="EXISTENCE:mutant phenotype:GO:0034599
cellular response to oxidative stress [PMID:14586471]"
/note="Sulfiredoxin; contributes to oxidative stress
resistance by reducing cysteine-sulfinic acid groups in
the peroxiredoxin Tsa1p, which is formed upon exposure to
oxidants; conserved in higher eukaryotes; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="sulfiredoxin"
/protein_id="DAA09072.1"
/db_xref="SGD:S000001569"
/translation="MSLQSNSVKPTEIPLSEIRRPLAPVLDPQKIDAMVATMKGIPTA
SKTCSLEQAEAAASAGELPPVDVLGVRVKGQTLYYAFGGCHRLQAYDRRARETQNAAF
PVRCRVLPATPRQIRMYLGSSLDIE"
gene 279123..280127
/gene="MDH1"
/locus_tag="YKL085W"
mRNA 279123..280127
/gene="MDH1"
/locus_tag="YKL085W"
/product="malate dehydrogenase MDH1"
CDS 279123..280127
/gene="MDH1"
/locus_tag="YKL085W"
/EC_number="1.1.1.37"
/experiment="EXISTENCE:direct assay:GO:0003729 mRNA
binding [PMID:21124907]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:11502169|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005759
mitochondrial matrix [PMID:9774331]"
/experiment="EXISTENCE:direct assay:GO:0030060 L-malate
dehydrogenase activity [PMID:1898005]"
/experiment="EXISTENCE:mutant phenotype:GO:0005739
mitochondrion [PMID:10777592]"
/experiment="EXISTENCE:mutant phenotype:GO:0006099
tricarboxylic acid cycle [PMID:3312168]"
/experiment="EXISTENCE:mutant phenotype:GO:0009060 aerobic
respiration [PMID:3312168]"
/experiment="EXISTENCE:mutant phenotype:GO:0030060
L-malate dehydrogenase activity [PMID:10777592]"
/experiment="EXISTENCE:physical interaction:GO:0005739
mitochondrion [PMID:16962558]"
/note="Mitochondrial malate dehydrogenase; catalyzes
interconversion of malate and oxaloacetate; involved in
the tricarboxylic acid (TCA) cycle; phosphorylated;
mutation in human homolog MDH2 causes early-onset severe
encephalopathy"
/codon_start=1
/product="malate dehydrogenase MDH1"
/protein_id="DAA09073.1"
/db_xref="SGD:S000001568"
/translation="MLSRVAKRAFSSTVANPYKVTVLGAGGGIGQPLSLLLKLNHKVT
DLRLYDLKGAKGVATDLSHIPTNSVVKGFTPEEPDGLNNALKDTDMVLIPAGVPRKPG
MTRDDLFAINASIVRDLAAATAESAPNAAILVISNPVNSTVPIVAQVLKNKGVYNPKK
LFGVTTLDSIRAARFISEVENTDPTQERVNVIGGHSGITIIPLISQTNHKLMSDDKRH
ELIHRIQFGGDEVVKAKNGAGSATLSMAHAGAKFANAVLSGFKGERDVIEPSFVDSPL
FKSEGIEFFASPVTLGPDGIEKIHPIGELSSEEEEMLQKCKETLKKNIEKGVNFVASK
"
gene 280509..280859
/gene="HOT13"
/locus_tag="YKL084W"
mRNA 280509..280859
/gene="HOT13"
/locus_tag="YKL084W"
/product="Hot13p"
CDS 280509..280859
/gene="HOT13"
/locus_tag="YKL084W"
/experiment="EXISTENCE:direct assay:GO:0005758
mitochondrial intermembrane space [PMID:15294910]"
/experiment="EXISTENCE:direct assay:GO:0008270 zinc ion
binding [PMID:18787558]"
/experiment="EXISTENCE:mutant phenotype:GO:0045041 protein
import into mitochondrial intermembrane space
[PMID:15294910]"
/note="Zinc-binding mitochondrial intermembrane space
(IMS) protein; involved in a disulfide relay system for
IMS import of cysteine-containing proteins; binds Mia40p
and stimulates its Erv1p-dependent oxidation, probably by
sequestering zinc"
/codon_start=1
/product="Hot13p"
/protein_id="DAA09074.1"
/db_xref="SGD:S000001567"
/translation="MIETAIYGKTVDDQSRCVHWHLPKDVIAIRFKCCDKYYACFECH
QELSSHPLEKYDLLDDANKHLIICGVCRHEMTFAEYYDYNSNLICPNCRSPFNPGCKL
HYHLYFQNPPPAMC"
gene complement(281025..282329)
/gene="RRP14"
/locus_tag="YKL082C"
mRNA complement(281025..282329)
/gene="RRP14"
/locus_tag="YKL082C"
/product="ribosome biosynthesis protein RRP14"
CDS complement(281025..282329)
/gene="RRP14"
/locus_tag="YKL082C"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:11489916|PMID:17804645]"
/experiment="EXISTENCE:mutant phenotype:GO:0042273
ribosomal large subunit biogenesis
[PMID:17272295|PMID:17804645]"
/experiment="EXISTENCE:mutant phenotype:GO:0042274
ribosomal small subunit biogenesis [PMID:17272295]"
/note="Essential protein, constituent of 66S pre-ribosomal
particles; interacts with proteins involved in ribosomal
biogenesis and cell polarity; member of the SURF-6 family"
/codon_start=1
/product="ribosome biosynthesis protein RRP14"
/protein_id="DAA09075.1"
/db_xref="SGD:S000001565"
/translation="MSNSLEERLRANSSAFDGLLALIPAKYYYDEKSQEQWKAKKKTK
EQSKNDKLKKLDPEQRDDETSSTLEVMKKKEKDAKPVVLPGEKFKHMKMQKQKEATSK
VEGDSDLNVEVNDPMIIAPDEDEEEEEDIKVIFDDEGNEIPLESKKDTTEPDRSVEKK
SITEEEKLQRKKNLEALRSKLQAKISDMKSKRKAPGSREAILAQRKRKEELKKRKRLE
SEQEQDQDEIASDSDMEDIDSDLENNSKKRFKKGKKDSEINADGVMFQNIIFDDGARA
TSDLQRLRKAGRTKGPAKNDVKSHLKLLEAKKNKMEAKDELEQIKQKEKEKWQKAMLQ
AEGIKIRDDEKLLRKAIKRKEAQKRKSAIEWSERKRVVEDTISERQKRREENLRIRKD
NKGKKRNKQEKMKRKYVGSAVPKKRAGFEGRLKTGKKKGGPK"
gene 282891..284455
/gene="TEF4"
/locus_tag="YKL081W"
/gene_synonym="EFC1"
mRNA join(282891..283095,283422..284455)
/gene="TEF4"
/locus_tag="YKL081W"
/gene_synonym="EFC1"
/product="translation elongation factor EF1B gamma"
CDS join(282891..283095,283422..284455)
/gene="TEF4"
/locus_tag="YKL081W"
/gene_synonym="EFC1"
/experiment="EXISTENCE:direct assay:GO:0005085
guanyl-nucleotide exchange factor activity [PMID:3528160]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0006414
translational elongation [PMID:3528160]"
/experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
stress granule [PMID:23451152|PMID:26777405]"
/note="Gamma subunit of translational elongation factor
eEF1B; stimulates the binding of aminoacyl-tRNA (AA-tRNA)
to ribosomes by releasing eEF1A (Tef1p/Tef2p) from the
ribosomal complex"
/codon_start=1
/product="translation elongation factor EF1B gamma"
/protein_id="DAA09076.1"
/db_xref="SGD:S000001564"
/translation="MSQGTLYINRSPRNYASEALISYFKLDVKIVDLEQSSEFASLFP
LKQAPAFLGPKGLKLTEALAIQFYLANQVADEKERARLLGSDVIEKSQILRWASLANS
DVMSNIARPFLSFKGLIPYNKKDVDACFVKIDNLAAVFDARLRDYTFVATENISLGDL
HAAGSWAFGLATILGPEWRAKHPHLMRWFNTVAASPIVKTPFAEVKLAEKALTYTPPK
KQKAEKPKAEKSKAEKKKDEAKPADDAAPAKKPKHPLEALGKSTFVLDDWKRKYSNDD
TRPVALPWFWEHYNPEEYSIWKVGYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGC
LVVYGENNNNGIVGAVMVRGQDFAPAFDVAPDWESYEYTKLDPTKEEDKEFVNNMWAW
DKPVVVNGEDKEIVDGKVLK"
gene 283185..283279
/gene="SNR38"
/locus_tag="YNCK0009W"
ncRNA 283185..283279
/ncRNA_class="snoRNA"
/gene="SNR38"
/locus_tag="YNCK0009W"
/product="SNR38"
/experiment="EXISTENCE:curator inference:GO:0005730
nucleolus [PMID:8674114]"
/experiment="EXISTENCE:curator inference:GO:0031428 box
C/D RNP complex [PMID:8674114]"
/note="C/D box small nucleolar RNA (snoRNA); guides
2'-O-methylation of large subunit (LSU) rRNA at position
G2815"
/db_xref="SGD:S000007301"
gene 285030..286208
/gene="VMA5"
/locus_tag="YKL080W"
/gene_synonym="CSL5"
/gene_synonym="VAT3"
mRNA 285030..286208
/gene="VMA5"
/locus_tag="YKL080W"
/gene_synonym="CSL5"
/gene_synonym="VAT3"
/product="H(+)-transporting V1 sector ATPase subunit C"
CDS 285030..286208
/gene="VMA5"
/locus_tag="YKL080W"
/gene_synonym="CSL5"
/gene_synonym="VAT3"
/experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
vacuole membrane [PMID:26928762]"
/note="Subunit C of the V1 peripheral membrane domain of
V-ATPase; part of the electrogenic proton pump found
throughout the endomembrane system; required for the V1
domain to assemble onto the vacuolar membrane; the V1
peripheral membrane domain of vacuolar H+-ATPase
(V-ATPase) has eight subunits"
/codon_start=1
/product="H(+)-transporting V1 sector ATPase subunit C"
/protein_id="DAA09077.1"
/db_xref="SGD:S000001563"
/translation="MATALYTANDFILISLPQNAQPVTAPGSKTDSWFNETLIGGRAF
VSDFKIPEFKIGSLDTLIVESEELSKVDNQIGASIGKIIEILQGLNETSTNAYRTLPI
NNMPVPEYLENFQWQTRKFKLDKSIKDLITLISNESSQLDADVRATYANYNSAKTNLA
AAERKKTGDLSVRSLHDIVKPEDFVLNSEHLTTVLVAVPKSLKSDFEKSYETLSKNVV
PASASVIAEDAEYVLFNVHLFKKNVQEFTTAAREKKFIPREFNYSEELIDQLKKEHDS
AASLEQSLRVQLVRLAKTAYVDVFINWFHIKALRVYVESVLRYGLPPHFNIKIIAVPP
KNLSKCKSELIDAFGFLGGNAFMKDKKGKINKQDTSLHQYASLVDTEYEPFVMYIINL
"
gene 286603..288573
/gene="SMY1"
/locus_tag="YKL079W"
mRNA 286603..288573
/gene="SMY1"
/locus_tag="YKL079W"
/product="Smy1p"
CDS 286603..288573
/gene="SMY1"
/locus_tag="YKL079W"
/experiment="EXISTENCE:direct assay:GO:0000131 incipient
cellular bud site [PMID:8188749]"
/experiment="EXISTENCE:direct assay:GO:0005934 cellular
bud tip [PMID:8188749|PMID:9472039]"
/experiment="EXISTENCE:direct assay:GO:0005935 cellular
bud neck [PMID:8188749]"
/experiment="EXISTENCE:direct assay:GO:0043332 mating
projection tip [PMID:19053807|PMID:8188749]"
/experiment="EXISTENCE:genetic interaction:GO:0006904
vesicle docking involved in exocytosis [PMID:27307583]"
/experiment="EXISTENCE:mutant phenotype:GO:0003774
cytoskeletal motor activity [PMID:9472039]"
/experiment="EXISTENCE:physical interaction:GO:0005515
protein binding [PMID:27307583]"
/note="Kinesin-like myosin passenger-protein; interacts
with Myo2p and enhances its interaction with Sec4p during
transport of secretory vesicles; controls actin cable
structure and dynamics"
/codon_start=1
/product="Smy1p"
/protein_id="DAA09078.1"
/db_xref="SGD:S000001562"
/translation="MHWNIISKEQSSSSVSLPTLDSSEPCHIEVILRAIPEKGLQNNE
STFKIDPYENTVLFRTNNPLHETTKETHSTFQFDKVFDANATQEDVQKFLVHPIINDV
LNGYNGTVITYGPSFSGKSYSLIGSKESEGILPNICKTLFDTLEKNEETKGDSFSVSV
LAFEIYMEKTYDLLVPLPERKPLKLHRSSSKMDLEIKDICPAHVGSYEDLRSYIQAVQ
NVGNRMACGDKTERSRSHLVFQLHVEQRNRKDDILKNSSLYLVDLHGAEKFDKRTEST
LSQDALKKLNQSIEALKNTVRSLSMKERDSAYSAKGSHSSAYRESQLTEVLKDSLGGN
RKTKVILTCFLSNVPTTLSTLEFGDSIRQINNKVTDNTTGLNLKKKMDLFIQDMKIKD
DNYVAQINILKAEIDSLKSLHNKSLPEDDEKKMLENTKKENIKLKLQLDSITQLLSSS
TNEDPNNRIDEEVSEILTKRCEQIAQLELSFDRQMNSNSKLQQELEYKKSKEEALESM
NVRLLEQIQLQEREIQELLTTNAILKGELETHTKLTETRSERIKSLESSVKELSLNKS
AIPSPRRGSMSSSSGNTMLHIEEGSEISNSPWSANTSSKPLVWGARKVSSSSIATTGS
QESFVARPFKKGLNLHSIKVTSSTPKSPSSGS"
gene 288845..291052
/gene="DHR2"
/locus_tag="YKL078W"
mRNA 288845..291052
/gene="DHR2"
/locus_tag="YKL078W"
/product="RNA helicase"
CDS 288845..291052
/gene="DHR2"
/locus_tag="YKL078W"
/EC_number="3.6.4.13"
/experiment="EXISTENCE:direct assay:GO:0003724 RNA
helicase activity [PMID:10982841]"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:10982841]"
/experiment="EXISTENCE:direct assay:GO:0042254 ribosome
biogenesis [PMID:10982841]"
/experiment="EXISTENCE:mutant phenotype:GO:0000462
maturation of SSU-rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16449634]"
/note="Predominantly nucleolar DEAH-box ATP-dependent RNA
helicase; required for 18S rRNA synthesis"
/codon_start=1
/product="RNA helicase"
/protein_id="DAA09079.1"
/db_xref="SGD:S000001561"
/translation="MAANSNSRVASNHTSKKQKVRRNIHPFTNNTRIKRASKIVKFND
SGEGDHVSDQRSNKENVLTYKSLKSRASDLLKMRETLPVYQHKREIMSYIESNPVTVL
IGETGSGKSTQIPQFVLEKLYDTKKHGSIAVTQPRRVAAINLATRVAQEHGCKLGEQV
GYSVRFDNTTTTRTRLKYLTDGMLLRELMMNSDLREYSVIVIDEAHERTVLTDLILGF
LKSLIQGPRPDLRIIVMSATLQAEKFSEFFNNAPILFVEGRKFDVKQYYLKAPTDDIV
DAVIRCCIQINQGEELGDILCFLPGQEEIDKAVTIMEKIAKYVSDEAPVPLIVPYPLY
AALPAVQQSLVFAPIKGFKRKVVFSTNIAETSVTISGVKFVVDSGLRKVKVWRHQLGL
ATLLTVPISQASAMQRSGRAGRESEGKSFRLYCESDYVKLPKQSEPEIARSDVTSPVL
MLKRYGVDDLLNWTWFENPGKEAIVMGLQELYELGALDTRGKITKRGQQMALLPLQPH
LSSVLIKASEVGCLSQVIDIVSCLSVENLLLNPSPEERDEVNERRLSLCNAGKRYGDL
IMLKELFDIYFYELGKSQDASSERNDWCKGLCISIRGFKNVIRVRDQLRVYCKRLFSS
ISEEDEESKKIGEDGELISKILKCFLTGFIKNTAIGMPDRSYRTVSTGEPISIHPSSM
LFMNKSCPGIMYTEYVFTTKGYARNVSRIELSWLQEVVTNAAAVAKQKVSDSK"
gene 291453..292631
/gene="PSG1"
/locus_tag="YKL077W"
mRNA 291453..292631
/gene="PSG1"
/locus_tag="YKL077W"
/product="Psg1p"
CDS 291453..292631
/gene="PSG1"
/locus_tag="YKL077W"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:28727280]"
/experiment="EXISTENCE:mutant phenotype:GO:0006605 protein
targeting [PMID:28727280]"
/experiment="EXISTENCE:mutant phenotype:GO:0051604 protein
maturation [PMID:28727280]"
/note="Protein that promotes the transport and maturation
of Pma1 with Exp1; cleaved specifically by Kex2p;
localizes to the Golgi apparatus and to the endoplasmic
reticulum in HTP studies"
/codon_start=1
/product="Psg1p"
/protein_id="DAA09080.1"
/db_xref="SGD:S000001560"
/translation="MRFHDSILIFFSLASLYQHVHGARQVVRPKEKMTTSEEVKPWLR
TVYGSQKELVTPTVIAGVTFSEKPEETPNPLKPWVSLEHDGRPKTIKPEINKGRTKKG
RPDYSTYFKTVSSHTYSYEELKAHNMGPNEVFVEEEYIDEDDTYVSLNPIVRCTPNLY
FNKGLAKDIRSEPFCTPYENSRWKVDKTYFVTWYTRFFTDENSGKVADKVRVHLSYVK
ENPVEKGNYKRDIPATFFSSEWIDNDNGLMPVEVRDEWLQDQFDRRIVVSVQPIYISD
EDFDPLQYGILLYITKGSKVFKPTKEQLALDDAGITNDQWYYVALSIPTVVVVFFVFM
YFFLYVNGKNRDFTDVTRKALNKKRRVLGKFSEMKKFKNMKNHKYTELPSYKKTSKQN
"
gene complement(292956..294308)
/gene="AAN1"
/locus_tag="YKL075C"
mRNA complement(292956..294308)
/gene="AAN1"
/locus_tag="YKL075C"
/product="Aan1p"
CDS complement(292956..294308)
/gene="AAN1"
/locus_tag="YKL075C"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:35577788]"
/experiment="EXISTENCE:mutant phenotype:GO:0009081
branched-chain amino acid metabolic process
[PMID:35577788]"
/experiment="EXISTENCE:mutant phenotype:GO:0009410
response to xenobiotic stimulus [PMID:16121259]"
/note="hypothetical protein; regulates actin cable
stability and branched-chain amino acid (BCAA) metabolism;
involved in mitochondrial quality control and longevity;
proposed to be involved in resistance to streptozotocin
and camptothecin; localizes to punctate cytosolic
structures"
/codon_start=1
/product="Aan1p"
/protein_id="DAA09081.1"
/db_xref="SGD:S000001558"
/translation="MAKDLLPKQAANEPSLKDCTCKRCLKLGASKEKKIRRKKKGEEK
RERHYGNRRKLTFNFLKHTNMENTNYDVITSVGYLNEKYGLKKSHYIEKFIKCIHRKI
NIDVSKITDAYVNSLNPWVKVKLFLLLVTLSEKGGPEYWLDKTDGEKNSEASSTDNSL
ENSTKGADSAGSTALRDEMVKSHKNLFPTLTEQIIQHNINQDFTESTYDEDYVFSSIW
ANFMEGLINHYLEKVIVPYSEMKVCQQLYKPMMKIISLYNEYNELMVKSEKNGFLPSL
QDSENVQGDKGEKESKDDAVSQERLERAQKLLWQAREDIPKTISKELTLLSEMYSTLS
ADEQDYELDEFVCCAEEYIELEYLPALVDVLFANCGTNNFWKIMLVLEPFFYYIEDVG
GDDDEDEDNVDNSEGDEESLLSRNVEGDDNVVERHFKPDPRVITLEKICEVAARQKWI
"
gene complement(294610..296193)
/gene="MUD2"
/locus_tag="YKL074C"
mRNA complement(294610..296193)
/gene="MUD2"
/locus_tag="YKL074C"
/product="Mud2p"
CDS complement(294610..296193)
/gene="MUD2"
/locus_tag="YKL074C"
/experiment="EXISTENCE:direct assay:GO:0000243 commitment
complex [PMID:7926772]"
/experiment="EXISTENCE:direct assay:GO:0003729 mRNA
binding [PMID:23222640]"
/experiment="EXISTENCE:direct assay:GO:0045131 pre-mRNA
branch point binding [PMID:7926772]"
/experiment="EXISTENCE:genetic interaction:GO:0000348 mRNA
branch site recognition [PMID:18375978]"
/experiment="EXISTENCE:mutant phenotype:GO:0000243
commitment complex [PMID:7926772]"
/experiment="EXISTENCE:mutant phenotype:GO:0000348 mRNA
branch site recognition [PMID:9130720]"
/note="Protein involved in early pre-mRNA splicing;
component of the pre-mRNA-U1 snRNP complex, the commitment
complex; interacts with Msl5p/BBP splicing factor and
Sub2p; similar to metazoan splicing factor U2AF65"
/codon_start=1
/product="Mud2p"
/protein_id="DAA09082.1"
/db_xref="SGD:S000001557"
/translation="MADEKRLEDLRSKIMESIGKSEKDVVPIENKRFNTDNAVIDTHF
KRQKSDGELPKAPKSRNVSHSNNRGPSSIITMSTNRTTYEQTRAGPHRQSYRDASGRS
YNRENRYSSHNTGPQWNNNPYNRQRDERRGRNERFDRRGRNGNGNYDRFNYQRKNEGS
KFNGDRDKRQLQTNKYDMNYNSQNVMYPGSSFDSPAYYNMASSKANSRLVISGLSQSS
DPSIVARLKDLLENFISGLQKTESNAEDFKISNFYIGEGRPDHIIVEFSSQICSTMVL
ACRSFFNAKLGTFDLKWRRPNDYVQQLDHLVDFCRGTVIALENLENIGEGEDYRMKEL
FSSLNVTNGTAKPLFYKCSSNTNNTGKESEFTKCILLSFEVVTQDILDKLKPYKWFKP
NDGKISQVTSWITFQSLPNLVTQSVRVESRVLLLLNCLDPLDLKDETFITEIKETLKY
SIAGADTIKICQPGVDYRLNFENLASGAGNIYIKFKTLEAAKHAMEELPGTQFNDRTV
LCTYIDEDDFDMMEATQLS"
gene 296430..299075
/gene="LHS1"
/locus_tag="YKL073W"
/gene_synonym="CER1"
/gene_synonym="SSI1"
mRNA 296430..299075
/gene="LHS1"
/locus_tag="YKL073W"
/gene_synonym="CER1"
/gene_synonym="SSI1"
/product="Hsp70 family chaperone LHS1"
CDS 296430..299075
/gene="LHS1"
/locus_tag="YKL073W"
/gene_synonym="CER1"
/gene_synonym="SSI1"
/experiment="EXISTENCE:direct assay:GO:0000774
adenyl-nucleotide exchange factor activity
[PMID:14704430]"
/experiment="EXISTENCE:direct assay:GO:0005524 ATP binding
[PMID:19759005]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005788 endoplasmic
reticulum lumen [PMID:8654361|PMID:8887673]"
/experiment="EXISTENCE:mutant phenotype:GO:0005524 ATP
binding [PMID:19759005]"
/experiment="EXISTENCE:mutant phenotype:GO:0006986
response to unfolded protein [PMID:8654361|PMID:8887673]"
/experiment="EXISTENCE:mutant phenotype:GO:0031204
post-translational protein targeting to membrane,
translocation [PMID:8654361|PMID:8887673]"
/experiment="EXISTENCE:mutant phenotype:GO:0051082
unfolded protein binding
[PMID:10409721|PMID:8654361|PMID:8887673]"
/note="Molecular chaperone of the endoplasmic reticulum
lumen; involved in polypeptide translocation and folding;
nucleotide exchange factor for the ER lumenal Hsp70
chaperone Kar2p; regulated by the unfolded protein
response pathway"
/codon_start=1
/product="Hsp70 family chaperone LHS1"
/protein_id="DAA09083.1"
/db_xref="SGD:S000001556"
/translation="MRNVLRLLFLTAFVAIGSLAAVLGVDYGQQNIKAIVVSPQAPLE
LVLTPEAKRKEISGLSIKRLPGYGKDDPNGIERIYGSAVGSLATRFPQNTLLHLKPLL
GKSLEDETTVTLYSKQHPGLEMVSTNRSTIAFLVDNVEYPLEELVAMNVQEIANRANS
LLKDRDARTEDFVNKMSFTIPDFFDQHQRKALLDASSITTGIEETYLVSEGMSVAVNF
VLKQRQFPPGEQQHYIVYDMGSGSIKASMFSILQPEDTTQPVTIEFEGYGYNPHLGGA
KFTMDIGSLIENKFLETHPAIRTDELHANPKALAKINQAAEKAKLILSANSEASINIE
SLINDIDFRTSITRQEFEEFIADSLLDIVKPINDAVTKQFGGYGTNLPEINGVILAGG
SSRIPIVQDQLIKLVSEEKVLRNVNADESAVNGVVMRGIKLSNSFKTKPLNVVDRSVN
TYSFKLSNESELYDVFTRGSAYPNKTSILTNTTDSIPNNFTIDLFENGKLFETITVNS
GAIKNSYSSDKCSSGVAYNITFDLSSDRLFSIQEVNCICQSENDIGNSKQIKNKGSRL
AFTSEDVEIKRLSPSERSRLHEHIKLLDKQDKERFQFQENLNVLESNLYDARNLLMDD
EVMQNGPKSQVEELSEMVKVYLDWLEDASFDTDPEDIVSRIREIGILKKKIELYMDSA
KEPLNSQQFKGMLEEGHKLLQAIETHKNTVEEFLSQFETEFADTIDNVREEFKKIKQP
AYVSKALSTWEETLTSFKNSISEIEKFLAKNLFGEDLREHLFEIKLQFDMYRTKLEEK
LRLIKSGDESRLNEIKKLHLRNFRLQKRKEEKLKRKLEQEKSRNNNETESTVINSADD
KTTIVNDKTTESNPSSEEDILHDEL"
gene 299582..301882
/gene="STB6"
/locus_tag="YKL072W"
mRNA 299582..301882
/gene="STB6"
/locus_tag="YKL072W"
/product="Stb6p"
CDS 299582..301882
/gene="STB6"
/locus_tag="YKL072W"
/note="Protein that binds Sin3p in a two-hybrid assay;
STB6 has a paralog, STB2, that arose from the whole genome
duplication"
/codon_start=1
/product="Stb6p"
/protein_id="DAA09084.1"
/db_xref="SGD:S000001555"
/translation="MQLEATHQKENHLSPLASFIFPDFRALFNIGFNLYSNINYKEVD
INGFEIYIVEQWAAQRKISTLITSYTGNLQDTISAVEVALPEDPEEWPCCLKKYHEEL
LKFSSPKKTAKGTLFVTNLSSFKSTLNLLHVECGNLKKIWKNFKTNYDLKRLHCGGRS
AQLLKKTPSASIAKFAQLYKFPNSAFSHEITSDFQQPSLQNDNSSISSIENIPVNHCP
VVELTTLVQISLSYFALFEYKKERDGLLCNGTKQSLEKWWEIYGKRYHGIDKPKNETI
LGPTTVASLLSLVLTCYFKLMVEDCMSAKDPFDEEEFYSGLYAFQKKYGLSKNNKQTS
LDELTIDKLFEVSSKTSNKDIFKFKKVVKSTVQDMTGKGNFMHLSNEILTTDLDTLVK
NIHGGSLGKLWKGRSASRKETCMVWERKTFLSFKFERGDPSLQLENNELFYGTSVPSE
QLTTSNKEDSDTQPTKRNSIYDIANGSKSSLSISSMFCNYDETRYKSTNNLNRAYRGE
YFRRNSIPFCNDGIHDTKKISADLNKIDGLYRCNSYSEVQNAIELWSLPFDSSVIRLA
RDLLKIQSLMSVQRQLDEIRDGYLGKNSQRSYQNDLMFRQSLNKLQEMCERCKRGSNE
FHWEYGNMQNKQQILESEKKDMKSLSSKLKYNVRILDRRVRDVEASVDHFDRKLEDVR
KKLLEQNNSKDISMALESPCDKFEFDSFMDSIVQSQQTKYEGLCFKILDKKSLRKLKK
EFWKWSTWTFDTFLYKNRPNKEKDTL"
repeat_region complement(302334..302625)
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007052"
gene 302918..303023
/locus_tag="YNCK0010W"
tRNA join(302918..302953,302988..303023)
/locus_tag="YNCK0010W"
/product="tRNA-Trp"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Tryptophan tRNA (tRNA-Trp), predicted by
tRNAscan-SE analysis"
/db_xref="SGD:S000006774"
gene 305114..305884
/gene="OSI1"
/locus_tag="YKL071W"
mRNA 305114..305884
/gene="OSI1"
/locus_tag="YKL071W"
/product="Osi1p"
CDS 305114..305884
/gene="OSI1"
/locus_tag="YKL071W"
/experiment="EXISTENCE:direct assay:GO:0004029 aldehyde
dehydrogenase (NAD+) activity [PMID:29034432]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:mutant phenotype:GO:0110095
cellular detoxification of aldehyde [PMID:19854918]"
/note="NADH-dependent short-chain aldehyde reductase;
involved in detoxification of furfural; expression is
upregulated in cells treated with the aldehydes furfural
and glycolaldehyde, the mycotoxin patulin, and also the
quinone methide triterpene celastrol; green fluorescent
protein (GFP)-fusion protein localizes to the cytoplasm"
/codon_start=1
/product="Osi1p"
/protein_id="DAA09085.1"
/db_xref="SGD:S000001554"
/translation="MNTSSRITYFIIGGSRGIGFNLVKILSASTGNTVITSIRGSPSL
PKNKQVEDLAKIRKNIHIVQLDLTKDESIGNIADEIKKTPFFLGIDIFIACSAVSDSY
YKVLETPKSVWLNHYSTNALGPILALQKVYPLLLLKKTRKIFFISSVAGSINAFVPLS
VSAYGQSKAALNYAVKTLSFELKPEGFTVVAFHPGMVSTDMGQYGLDHFKEKNIDISG
VNIITPEESASALIDVFRKILPEDNGKFFNYDGSEGVF"
gene 306211..306720
/locus_tag="YKL070W"
mRNA 306211..306720
/locus_tag="YKL070W"
/product="hypothetical protein"
CDS 306211..306720
/locus_tag="YKL070W"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/note="hypothetical protein; expression induced in cells
treated with mycotoxins patulin or citrinin; the
authentic, non-tagged protein is detected in highly
purified mitochondria in high-throughput studies"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09086.1"
/db_xref="SGD:S000001553"
/translation="MYIPKHFESMELSRYKLSKKPPLGTLFSSKASRQGFFGWRTSSN
KDDPDFGMCASHIPFVFVEFDNGEHKLIAHLARKNKHVEMLERVQKCLVVFQSVDSYI
SPAWFPMKKKTHKFVPTWDFAAVHVYGTPRIIRDDKDWLINMLSTLTDQEEEKRPEGE
NVRSKVERF"
gene 307285..307827
/locus_tag="YKL069W"
/gene_synonym="YKG9"
mRNA 307285..307827
/locus_tag="YKL069W"
/gene_synonym="YKG9"
/product="L-methionine (R)-S-oxide reductase"
CDS 307285..307827
/locus_tag="YKL069W"
/gene_synonym="YKG9"
/EC_number="1.8.4.14"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095|PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095|PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0033745
L-methionine-(R)-S-oxide reductase activity
[PMID:19049972]"
/experiment="EXISTENCE:mutant phenotype:GO:0034599
cellular response to oxidative stress [PMID:19049972]"
/note="Methionine-R-sulfoxide reductase; reduces the R
enantiomer of free Met-SO, in contrast to Ycl033Cp which
reduces Met-R-SO in a peptide linkage; has a role in
protection against oxidative stress; capable of binding
and degrading patulin, a polyketide mycotoxin, forming
E-ascladiol; relative distribution to the nucleus
increases upon DNA replication stress"
/codon_start=1
/product="L-methionine (R)-S-oxide reductase"
/protein_id="DAA09087.1"
/db_xref="SGD:S000001552"
/translation="MGSSTGFHHADHVNYSSNLNKEEILEQLLLSYEGLSDGQVNWVC
NLSNASSLIWHAYKSLAVDINWAGFYVTQASEENTLILGPFQGKVACQMIQFGKGVCG
TAASTKETQIVPDVNKYPGHIACDGETKSEIVVPIISNDGKTLGVIDIDCLDYEGFDH
VDKEFLEKLAKLINKSCVFK"
gene complement(308144..308217)
/locus_tag="YNCK0011C"
tRNA complement(308144..308217)
/locus_tag="YNCK0011C"
/product="tRNA-Val"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006760"
gene 309206..309442
/locus_tag="YKL068W-A"
mRNA 309206..309442
/locus_tag="YKL068W-A"
/product="hypothetical protein"
CDS 309206..309442
/locus_tag="YKL068W-A"
/note="hypothetical protein; identified by homology to
Ashbya gossypii"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09088.1"
/db_xref="SGD:S000028524"
/translation="MQANHSVSYLYESSTSKRSNGLFSQTQKQGSFQKALSQTQEEIE
DEDLMVDLNTGSLTPVKLKYWTQMSAMTEKFGKL"
gene 310199..313078
/gene="NUP100"
/locus_tag="YKL068W"
/gene_synonym="NSP100"
mRNA 310199..313078
/gene="NUP100"
/locus_tag="YKL068W"
/gene_synonym="NSP100"
/product="FG-nucleoporin NUP100"
CDS 310199..313078
/gene="NUP100"
/locus_tag="YKL068W"
/gene_synonym="NSP100"
/experiment="EXISTENCE:direct assay:GO:0005643 nuclear
pore [PMID:10684247|PMID:8195299]"
/experiment="EXISTENCE:direct assay:GO:0017056 structural
constituent of nuclear pore [PMID:19098896]"
/experiment="EXISTENCE:direct assay:GO:0044613 nuclear
pore central transport channel [PMID:18046406]"
/experiment="EXISTENCE:genetic interaction:GO:0006606
protein import into nucleus [PMID:20647373]"
/experiment="EXISTENCE:genetic interaction:GO:0006607
NLS-bearing protein import into nucleus [PMID:15039779]"
/experiment="EXISTENCE:genetic interaction:GO:0017056
structural constituent of nuclear pore [PMID:20647373]"
/experiment="EXISTENCE:genetic interaction:GO:0036228
protein localization to nuclear inner membrane
[PMID:21659568]"
/experiment="EXISTENCE:genetic interaction:GO:0045893
positive regulation of DNA-templated transcription
[PMID:15817685]"
/experiment="EXISTENCE:mutant phenotype:GO:0000973
post-transcriptional tethering of RNA polymerase II gene
DNA at nuclear periphery [PMID:20932479]"
/experiment="EXISTENCE:mutant phenotype:GO:0017056
structural constituent of nuclear pore [PMID:17418788]"
/experiment="EXISTENCE:mutant phenotype:GO:0031990 mRNA
export from nucleus in response to heat stress
[PMID:18258809]"
/experiment="EXISTENCE:mutant phenotype:GO:2000238
regulation of tRNA export from nucleus [PMID:27932586]"
/experiment="EXISTENCE:physical interaction:GO:0006406
mRNA export from nucleus [PMID:11104765]"
/experiment="EXISTENCE:physical interaction:GO:0017056
structural constituent of nuclear pore
[PMID:19098896|PMID:12917401|PMID:17803941|PMID:17418788]"
/note="FG-nucleoporin component of central core of the
nuclear pore complex; contributes directly to
nucleocytoplasmic transport and maintenance of the nuclear
pore complex (NPC) permeability barrier and is involved in
gene tethering at the nuclear periphery; NUP100 has a
paralog, NUP116, that arose from the whole genome
duplication"
/codon_start=1
/product="FG-nucleoporin NUP100"
/protein_id="DAA09089.1"
/db_xref="SGD:S000001551"
/translation="MFGNNRPMFGGSNLSFGSNTSSFGGQQSQQPNSLFGNSNNNNNS
TSNNAQSGFGGFTSAAGSNSNSLFGNNNTQNNGAFGQSMGATQNSPFGSLNSSNASNG
NTFGGSSSMGSFGGNTNNAFNNNSNSTNSPFGFNKPNTGGTLFGSQNNNSAGTSSLFG
GQSTSTTGTFGNTGSSFGTGLNGNGSNIFGAGNNSQSNTTGSLFGNQQSSAFGTNNQQ
GSLFGQQSQNTNNAFGNQNQLGGSSFGSKPVGSGSLFGQSNNTLGNTTNNRNGLFGQM
NSSNQGSSNSGLFGQNSMNSSTQGVFGQNNNQMQINGNNNNSLFGKANTFSNSASGGL
FGQNNQQQGSGLFGQNSQTSGSSGLFGQNNQKQPNTFTQSNTGIGLFGQNNNQQQQST
GLFGAKPAGTTGSLFGGNSSTQPNSLFGTTNVPTSNTQSQQGNSLFGATKLTNMPFGG
NPTANQSGSGNSLFGTKPASTTGSLFGNNTASTTVPSTNGLFGNNANNSTSTTNTGLF
GAKPDSQSKPALGGGLFGNSNSNSSTIGQNKPVFGGTTQNTGLFGATGTNSSAVGSTG
KLFGQNNNTLNVGTQNVPPVNNTTQNALLGTTAVPSLQQAPVTNEQLFSKISIPNSIT
NPVKATTSKVNADMKRNSSLTSAYRLAPKPLFAPSSNGDAKFQKWGKTLERSDRGSST
SNSITDPESSYLNSNDLLFDPDRRYLKHLVIKNNKNLNVINHNDDEASKVKLVTFTTE
SASKDDQASSSIAASKLTEKAHSPQTDLKDDHDESTPDPQSKSPNGSTSIPMIENEKI
SSKVPGLLSNDVTFFKNNYYISPSIETLGNKSLIELRKINNLVIGHRNYGKVEFLEPV
DLLNTPLDTLCGDLVTFGPKSCSIYENCSIKPEKGEGINVRCRVTLYSCFPIDKETRK
PIKNITHPLLKRSIAKLKENPVYKFESYDPVTGTYSYTIDHPVLT"
gene complement(313401..313472)
/locus_tag="YNCK0012C"
tRNA complement(313401..313472)
/locus_tag="YNCK0012C"
/product="tRNA-His"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/experiment="EXISTENCE:direct assay:GO:0030371 translation
repressor activity [PMID:27609601]"
/experiment="EXISTENCE:direct assay:GO:0043022 ribosome
binding [PMID:27609601]"
/experiment="EXISTENCE:direct assay:GO:0043555 regulation
of translation in response to stress [PMID:27609601]"
/note="Histidine tRNA (tRNA-His), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006598"
repeat_region complement(313602..313919)
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007053"
repeat_region 314193..314524
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007057"
gene 314812..315273
/gene="YNK1"
/locus_tag="YKL067W"
/gene_synonym="NDK1"
mRNA 314812..315273
/gene="YNK1"
/locus_tag="YKL067W"
/gene_synonym="NDK1"
/product="nucleoside diphosphate kinase"
CDS 314812..315273
/gene="YNK1"
/locus_tag="YKL067W"
/gene_synonym="NDK1"
/EC_number="2.7.4.6"
/experiment="EXISTENCE:direct assay:GO:0004550 nucleoside
diphosphate kinase activity [PMID:12472466]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0005758
mitochondrial intermembrane space [PMID:12472466]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:12472466]"
/experiment="EXISTENCE:mutant phenotype:GO:0006974 DNA
damage response [PMID:18983998]"
/note="Nucleoside diphosphate kinase; catalyzes the
transfer of gamma phosphates from nucleoside
triphosphates, usually ATP, to nucleoside diphosphates by
a mechanism that involves formation of an
autophosphorylated enzyme intermediate; protein abundance
increases in response to DNA replication stress"
/codon_start=1
/product="nucleoside diphosphate kinase"
/protein_id="DAA09090.1"
/db_xref="SGD:S000001550"
/translation="MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVKA
DDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAP
GTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE"
gene 315954..316175
/gene="DPC7"
/locus_tag="YKL065W-A"
mRNA 315954..316175
/gene="DPC7"
/locus_tag="YKL065W-A"
/product="Dpc7p"
CDS 315954..316175
/gene="DPC7"
/locus_tag="YKL065W-A"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/note="hypothetical protein; SWAT-GFP fusion protein
localizes to endoplasmic reticulum (ER) while mCherry
fusion localizes to both ER and vacuole"
/codon_start=1
/product="Dpc7p"
/protein_id="DAA09091.1"
/db_xref="SGD:S000113563"
/translation="MRSNILKLLQRTSRRYVSSKDFEPVIGSNPKKQTSRLMVGSVGV
MIPVLLYLFYKNDSKHSEIKKIYQNEKKI"
gene complement(316437..317057)
/gene="YET1"
/locus_tag="YKL065C"
mRNA complement(316437..317057)
/gene="YET1"
/locus_tag="YKL065C"
/product="Yet1p"
CDS complement(316437..317057)
/gene="YET1"
/locus_tag="YKL065C"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:14562095|PMID:20378542|PMID:26928762]"
/note="Endoplasmic reticulum transmembrane protein; may
interact with ribosomes, based on co-purification
experiments; homolog of human BAP31 protein; YET1 has a
paralog, YET2, that arose from the whole genome
duplication"
/codon_start=1
/product="Yet1p"
/protein_id="DAA09092.2"
/db_xref="SGD:S000001548"
/translation="MSLYFTTLFLLLTVEMVMLFIFVLPLPFRIRRGIFSTYNQLTAK
QQIKTIIFITGCLVGLLFIDSWKRSQIRVSLYHNDNSGSIGSSAVTPIQALASRAYNQ
RNMYISGFILYFSICIPTVMSIVKRLVKYQGLINEQEKQKLNKPSSNSKKDSNEADST
KLQEELRKKQISLEGLQKQVKNLEKYFDEKNQPGNVAAAEASKKGN"
gene 317764..320673
/gene="MNR2"
/locus_tag="YKL064W"
mRNA 317764..320673
/gene="MNR2"
/locus_tag="YKL064W"
/product="putative Mg(2+) transporter MNR2"
CDS 317764..320673
/gene="MNR2"
/locus_tag="YKL064W"
/experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
vacuole membrane
[PMID:19001347|PMID:19720860|PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:1990816
vacuole-mitochondrion membrane contact site
[PMID:25026036]"
/experiment="EXISTENCE:mutant phenotype:GO:0010961
intracellular magnesium ion homeostasis [PMID:19720860]"
/experiment="EXISTENCE:mutant phenotype:GO:0015095
magnesium ion transmembrane transporter activity
[PMID:19720860]"
/note="Vacuolar membrane protein required for magnesium
homeostasis; putative magnesium transporter; has
similarity to Alr1p and Alr2p, which mediate influx of
Mg2+ and other divalent cations; localizes to sites of
contact between the vacuole and mitochondria (vCLAMPs)"
/codon_start=1
/product="putative Mg(2+) transporter MNR2"
/protein_id="DAA09093.1"
/db_xref="SGD:S000001547"
/translation="MSTDNSQKDEGVPLLSPYSSSPQLRKKKRNQKRRKDKFVGHLKS
DSRRPTQLLHDNLQHNHGQITDFDQIDSWGMLHESDSTSNDIIKSEDPSLKGAFIDHR
PSMSQPREGPQSVSSTVQPQPIMKFSTPSYKKPAGLRPSDQNRSLVSDLSPSELESWL
KRRKSVHKSFVDENSPTDRRQSNANNDVVIDVDALMNHVNNNASTGVNDNSKRRKKKR
GSDDSSNKNSKSTSSDSNDEEDEYNSRPSSSLSSNNSSLDDVCLVLDDEGSEVPKAWP
DCTVLEEFSKEETERLRSQAIQDAEAFHFQYDEDEEDGTSNEDGILFSKPIVTNIDVP
ELGNRRVNETENLKNGRLRPKRIAPWHLIQRPMVLGSNSTKDSKSRIQSGLQDNLLVG
RNIQYPPHIISNNPEHFRFTYFRVDLDSTVHSPTISGLLQPGQKFQDLFVASIYSQDN
SAGHIKTHPNSPTPGIKAETVSQLQGLTAKNPSTLSSMSVANIEDVPPFWLDVSNPTE
EEMKILSKAFGIHPLTTEDIFLGEVREKVELFRDYYLICFRSFDIVAEKHVRRRRKEK
QESATLDHESISRRKSQAYGATMSNESNANNNNSTSNASRSKWLPSILRARRRSSANR
TTNTSSSSYKRRVKSEKKKMEENEKFKRKSGDRHKPREGELEPLNVYIIVFRTGVLTF
HFAPTPHPINVRRRARLLKDYLNVTSDWIAYALIDDITDAFAPMIELIEDEVYEIEDA
ILKMHQSDDSSDSDSSDSDSDSGASDEDAFPFDVYSKKTSYSSAKSSVSSRSMSTSEA
SFNANLIGWKRKGDMLRRIGECRKRVMSILRLLGSKADVIKGFAKRYNEQWEASPQSE
IAMYLGDIQDHIVTMVSSLNHYEKLLSRSHSNYLAQINIDMTKVNNDMNDVLGKITIL
GTIVLPMNVITGLWGMNVIVPGQYRDSLTWFIGIVLFMCMLACSAYMYTKRRFGF"
gene complement(321015..321518)
/locus_tag="YKL063C"
mRNA complement(321015..321518)
/locus_tag="YKL063C"
/product="hypothetical protein"
CDS complement(321015..321518)
/locus_tag="YKL063C"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:14562095]"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the Golgi"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09094.1"
/db_xref="SGD:S000001546"
/translation="MQGDIRRKKDLLPRYKTGSKYNSRRRGGYLTTPMKKIIVYIILL
CGVYFVIKVAYSDLNKETEIKLESHSSDVSASASDHTNIAAGGAADATNNKQPQQAKV
PKEKFNNEVAKQQEVKNLENDLKPQIDSEKQKQINKDKKEQKQQLQKEKQDLAKENLA
NNEILDN"
gene 323228..325120
/gene="MSN4"
/locus_tag="YKL062W"
mRNA 323228..325120
/gene="MSN4"
/locus_tag="YKL062W"
/product="stress-responsive transcriptional activator
MSN4"
CDS 323228..325120
/gene="MSN4"
/locus_tag="YKL062W"
/experiment="EXISTENCE:direct assay:GO:0000981 DNA-binding
transcription factor activity, RNA polymerase II-specific
[PMID:23435728|PMID:27637775]"
/experiment="EXISTENCE:direct assay:GO:0000987
cis-regulatory region sequence-specific DNA binding
[PMID:8321194|PMID:8641288]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:12732613|PMID:9472026]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:12732613|PMID:9472026]"
/experiment="EXISTENCE:genetic interaction:GO:0006338
chromatin remodeling [PMID:18070923]"
/experiment="EXISTENCE:genetic interaction:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:20398213|PMID:27637775|PMID:10652100|PMID:11102521|P
MID:11179418|PMID:15053871|PMID:15483057|PMID:15922872|PMI
D:16710843|PMID:17055490|PMID:17150183|PMID:17914901|PMID:
19073887|PMID:21749328|PMID:26947009|PMID:19702872|PMID:86
41288]"
/experiment="EXISTENCE:mutant phenotype:GO:0000981
DNA-binding transcription factor activity, RNA polymerase
II-specific [PMID:27637775|PMID:8650168]"
/experiment="EXISTENCE:mutant phenotype:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:15922872|PMID:11102521]"
/experiment="EXISTENCE:physical interaction:GO:0005515
protein binding [PMID:27637775]"
/note="Stress-responsive transcriptional activator;
activated in stochastic pulses of nuclear localization in
response to various stress conditions; binds DNA at stress
response elements of responsive genes, inducing gene
expression; involved in diauxic shift"
/codon_start=1
/product="stress-responsive transcriptional activator
MSN4"
/protein_id="DAA09095.1"
/db_xref="SGD:S000001545"
/translation="MLVFGPNSSFVRHANKKQEDSSIMNEPNGLMDPVLSTTNVSATS
SNDNSANNSISSPEYTFGQFSMDSPHRTDATNTPILTATTNTTANNSLMNLKDTASLA
TNWKWKNSNNAQFVNDGEKQSSNANGKKNGGDKIYSSVATPQALNDELKNLEQLEKVF
SPMNPINDSHFNENIELSPHQHATSPKTNLLEAEPSIYSNLFLDARLPNNANSTTGLN
DNDYNLDDTNNDNTNSMQSILEDFVSSEEALKFMPDAGRDARRYSEVVTSSFPSMTDS
RNSISHSIEFWNLNHKNSSNSKPTQQIIPEGTATTERRGSTISPTTTINNSNPNFKLL
DHDVSQALSGYSMDFSKDSGITKPKSISSSLNRISHSSSTTRQQRASLPLIHDIESFA
NDSVMANPLSDSASFLSEENEDDAFGALNYNSLDATTMSAFDNNVDPFNILKSSPAQD
QQFIKPSMMLSDNASAAAKLATSGVDNITPTPAFQRRSYDISMNSSFKILPTSQAHHA
AQHHQQQPTKQATVSPNTRRRKSSSVTLSPTISHNNNNGKVPVQPRKRKSITTIDPNN
YDKNKPFKCKDCEKAFRRSEHLKRHIRSVHSTERPFACMFCEKKFSRSDNLSQHLKTH
KKHGDF"
gene 325771..326112
/gene="BLI1"
/locus_tag="YKL061W"
mRNA 325771..326112
/gene="BLI1"
/locus_tag="YKL061W"
/product="Bli1p"
CDS 325771..326112
/gene="BLI1"
/locus_tag="YKL061W"
/experiment="EXISTENCE:direct assay:GO:0005768 endosome
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0031083 BLOC-1
complex [PMID:23547030]"
/experiment="EXISTENCE:mutant phenotype:GO:0007032
endosome organization [PMID:23547030]"
/experiment="EXISTENCE:mutant phenotype:GO:0032880
regulation of protein localization [PMID:23547030]"
/note="Subunit of the BLOC-1 complex involved in endosomal
maturation; interacts with Msb3p; green fluorescent
protein (GFP)-fusion protein localizes to the endosome"
/codon_start=1
/product="Bli1p"
/protein_id="DAA09096.1"
/db_xref="SGD:S000001544"
/translation="MGEQNKLYYDVEKLVNSLQESFDLDCAQSVSLFTSKSRSNEAWL
EELENKFKLKDDVELDDVENLRAEIDMKLNMLEDKVSYYERLYKELEEFQNEIKIKTV
VNNRRQSRTPK"
gene complement(326408..327487)
/gene="FBA1"
/locus_tag="YKL060C"
/gene_synonym="LOT1"
mRNA complement(326408..327487)
/gene="FBA1"
/locus_tag="YKL060C"
/gene_synonym="LOT1"
/product="fructose-bisphosphate aldolase FBA1"
CDS complement(326408..327487)
/gene="FBA1"
/locus_tag="YKL060C"
/gene_synonym="LOT1"
/EC_number="4.1.2.13"
/experiment="EXISTENCE:direct assay:GO:0004332
fructose-bisphosphate aldolase activity [PMID:2647491]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16806052|PMID:16962558|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:16806052]"
/experiment="EXISTENCE:direct assay:GO:1904408 melatonin
binding [PMID:31708896]"
/experiment="EXISTENCE:mutant phenotype:GO:0004332
fructose-bisphosphate aldolase activity [PMID:2647491]"
/experiment="EXISTENCE:mutant phenotype:GO:0006094
gluconeogenesis [PMID:6384192]"
/experiment="EXISTENCE:mutant phenotype:GO:0006096
glycolytic process [PMID:6384192]"
/note="Fructose 1,6-bisphosphate aldolase; required for
glycolysis and gluconeogenesis; catalyzes conversion of
fructose 1,6 bisphosphate to glyceraldehyde-3-P and
dihydroxyacetone-P; locates to mitochondrial outer surface
upon oxidative stress; N-terminally propionylated in vivo"
/codon_start=1
/product="fructose-bisphosphate aldolase FBA1"
/protein_id="DAA09097.1"
/db_xref="SGD:S000001543"
/translation="MGVEQILKRKTGVIVGEDVHNLFTYAKEHKFAIPAINVTSSSTA
VAALEAARDSKSPIILQTSNGGAAYFAGKGISNEGQNASIKGAIAAAHYIRSIAPAYG
IPVVLHSDHCAKKLLPWFDGMLEADEAYFKEHGEPLFSSHMLDLSEETDEENISTCVK
YFKRMAAMDQWLEMEIGITGGEEDGVNNENADKEDLYTKPEQVYNVYKALHPISPNFS
IAAAFGNCHGLYAGDIALRPEILAEHQKYTREQVGCKEEKPLFLVFHGGSGSTVQEFH
TGIDNGVVKVNLDTDCQYAYLTGIRDYVLNKKDYIMSPVGNPEGPEKPNKKFFDPRVW
VREGEKTMGAKITKSLETFRTTNTL"
gene complement(328118..329443)
/gene="MPE1"
/locus_tag="YKL059C"
mRNA complement(328118..329443)
/gene="MPE1"
/locus_tag="YKL059C"
/product="cleavage polyadenylation factor subunit MPE1"
CDS complement(328118..329443)
/gene="MPE1"
/locus_tag="YKL059C"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:35584695|PMID:22932476]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:22932476]"
/experiment="EXISTENCE:direct assay:GO:0005847 mRNA
cleavage and polyadenylation specificity factor complex
[PMID:12819204]"
/experiment="EXISTENCE:direct assay:GO:0006369 termination
of RNA polymerase II transcription [PMID:35584695]"
/experiment="EXISTENCE:direct assay:GO:0036002 pre-mRNA
binding [PMID:25135474|PMID:35584695]"
/experiment="EXISTENCE:genetic interaction:GO:0016567
protein ubiquitination [PMID:25135474]"
/experiment="EXISTENCE:mutant phenotype:GO:0000209 protein
polyubiquitination [PMID:32009536]"
/experiment="EXISTENCE:mutant phenotype:GO:0016567 protein
ubiquitination [PMID:25135474]"
/experiment="EXISTENCE:mutant phenotype:GO:0036002
pre-mRNA binding [PMID:25135474]"
/experiment="EXISTENCE:mutant phenotype:GO:0061630
ubiquitin protein ligase activity [PMID:32009536]"
/note="Subunit of CPF cleavage and polyadenylation factor
and E3 Ub-ligase; detects polyadenylation signal in
nascent pre-mRNA and triggers 3' end formation of mRNA via
cleavage and polyadenylation; binds pre-mRNA via zinc
knuckle and RING finger; E3 ubiquitin ligase involved in
polyubiquitination of endonuclease Ysh1p; contains a
ubiquitin-like (UBL) domain, a RNA-binding zinc knuckle
motif and a RING finger domain; relocalizes to cytosol in
response to hypoxia; homolog of human RBBP6"
/codon_start=1
/product="cleavage polyadenylation factor subunit MPE1"
/protein_id="DAA09098.1"
/db_xref="SGD:S000001542"
/translation="MSSTIFYRFKSQRNTSRILFDGTGLTVFDLKREIIQENKLGDGT
DFQLKIYNPDTEEEYDDDAFVIPRSTSVIVKRSPAIKSFSVHSRLKGNVGAAALGNAT
RYVTGRPRVLQKRQHTATTTANVSGTTEEERIASMFATQENQWEQTQEEMSAATPVFF
KSQTNKNSAQENEGPPPPGYMCYRCGGRDHWIKNCPTNSDPNFEGKRIRRTTGIPKKF
LKSIEIDPETMTPEEMAQRKIMITDEGKFVVQVEDKQSWEDYQRKRENRQIDGDETIW
RKGHFKDLPDDLKCPLTGGLLRQPVKTSKCCNIDFSKEALENALVESDFVCPNCETRD
ILLDSLVPDQDKEKEVETFLKKQEELHGSSKDGNQPETKKMKLMDPTGTAGLNNNTSL
PTSVNNGGTPVPPVPLPFGIPPFPMFPMPFMPPTATITNPHQADASPKK"
rep_origin 329682..329930
/note="ARS1109; Autonomously Replicating Sequence"
/db_xref="SGD:S000118403"
gene 330166..330534
/gene="TOA2"
/locus_tag="YKL058W"
mRNA 330166..330534
/gene="TOA2"
/locus_tag="YKL058W"
/product="transcription initiation factor IIA subunit
gamma"
CDS 330166..330534
/gene="TOA2"
/locus_tag="YKL058W"
/experiment="EXISTENCE:direct assay:GO:0005672
transcription factor TFIIA complex [PMID:7862117]"
/experiment="EXISTENCE:direct assay:GO:0006367
transcription initiation at RNA polymerase II promoter
[PMID:7862117]"
/experiment="EXISTENCE:direct assay:GO:0017025 TBP-class
protein binding [PMID:7604282]"
/experiment="EXISTENCE:direct assay:GO:0051123 RNA
polymerase II preinitiation complex assembly
[PMID:15132995]"
/experiment="EXISTENCE:mutant phenotype:GO:0051123 RNA
polymerase II preinitiation complex assembly
[PMID:15132995]"
/note="TFIIA small subunit; involved in transcriptional
activation, acts as antirepressor or as coactivator;
required, along with Toa1p, for ribosomal protein gene
transcription in vivo; homologous to smallest subunit of
human and Drosophila TFIIA; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="transcription initiation factor IIA subunit
gamma"
/protein_id="DAA09099.1"
/db_xref="SGD:S000001541"
/translation="MAVPGYYELYRRSTIGNSLVDALDTLISDGRIEASLAMRVLETF
DKVVAETLKDNTQSKLTVKGNLDTYGFCDDVWTFIVKNCQVTVEDSHRDASQNGSGDS
QSVISVDKLRIVACNSKKSE"
gene complement(330856..333969)
/gene="NUP120"
/locus_tag="YKL057C"
/gene_synonym="RAT2"
mRNA complement(330856..333969)
/gene="NUP120"
/locus_tag="YKL057C"
/gene_synonym="RAT2"
/product="Nup120p"
CDS complement(330856..333969)
/gene="NUP120"
/locus_tag="YKL057C"
/gene_synonym="RAT2"
/experiment="EXISTENCE:direct assay:GO:0005643 nuclear
pore [PMID:10684247]"
/experiment="EXISTENCE:direct assay:GO:0031080 nuclear
pore outer ring [PMID:11823431]"
/experiment="EXISTENCE:direct assay:GO:0045893 positive
regulation of DNA-templated transcription [PMID:15817685]"
/experiment="EXISTENCE:genetic interaction:GO:0006302
double-strand break repair [PMID:15725626]"
/experiment="EXISTENCE:genetic interaction:GO:0045893
positive regulation of DNA-templated transcription
[PMID:15817685]"
/experiment="EXISTENCE:mutant phenotype:GO:0000055
ribosomal large subunit export from nucleus
[PMID:11071906]"
/experiment="EXISTENCE:mutant phenotype:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:22110603]"
/experiment="EXISTENCE:mutant phenotype:GO:0000973
post-transcriptional tethering of RNA polymerase II gene
DNA at nuclear periphery [PMID:20932479]"
/experiment="EXISTENCE:mutant phenotype:GO:0006302
double-strand break repair [PMID:16418532|PMID:17538013]"
/experiment="EXISTENCE:mutant phenotype:GO:0006406 mRNA
export from nucleus
[PMID:8557736|PMID:8557737|PMID:8565072]"
/experiment="EXISTENCE:mutant phenotype:GO:0006606 protein
import into nucleus [PMID:12730220]"
/experiment="EXISTENCE:mutant phenotype:GO:0006611 protein
export from nucleus [PMID:8557736]"
/experiment="EXISTENCE:mutant phenotype:GO:0017056
structural constituent of nuclear pore [PMID:22331846]"
/experiment="EXISTENCE:mutant phenotype:GO:0031509
subtelomeric heterochromatin formation [PMID:16418532]"
/experiment="EXISTENCE:mutant phenotype:GO:0031990 mRNA
export from nucleus in response to heat stress
[PMID:18258809]"
/experiment="EXISTENCE:mutant phenotype:GO:0034398
telomere tethering at nuclear periphery [PMID:16418532]"
/experiment="EXISTENCE:mutant phenotype:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:22110603]"
/experiment="EXISTENCE:mutant phenotype:GO:0051664 nuclear
pore localization
[PMID:22331846|PMID:8557736|PMID:8557737|PMID:8565072|PMID
:9725905]"
/note="Subunit of the Nup84p subcomplex of the nuclear
pore complex (NPC); contributes to nucleocytoplasmic
transport and NPC biogenesis and is involved in
establishment of a normal nucleocytoplasmic concentration
gradient of the GTPase Gsp1p; also plays roles in several
processes that may require localization of genes or
chromosomes at the nuclear periphery, including
double-strand break repair, transcription and chromatin
silencing; homologous to human NUP160"
/codon_start=1
/product="Nup120p"
/protein_id="DAA09100.1"
/db_xref="SGD:S000001540"
/translation="MACLSRIDANLLQYYEKPEPNNTVDLYVSNNSNNNGLKEGDKSI
STPVPQPYGSEYSNCLLLSNSEYICYHFSSRSTLLTFYPLSDAYHGKTINIHLPNASM
NQRYTLTIQEVEQQLLVNVILKDGSFLTLQLPLSFLFSSANTLNGEWFHLQNPYDFTV
RVPHFLFYVSPQFSVVFLEDGGLLGLKKVDGVHYEPLLFNDNSYLKSLTRFFSRSSKS
DYDSVISCKLFHERYLIVLTQNCHLKIWDLTSFTLIQDYDMVSQSDSDPSHFRKVEAV
GEYLSLYNNTLVTLLPLENGLFQMGTLLVDSSGILTYTFQNNIPTNLSASAIWSIVDL
VLTRPLELNVEASYLNLIVLWKSGTASKLQILNVNDESFKNYEWIESVNKSLVDLQSE
HDLDIVTKTGDVERGFCNLKSRYGTQIFERAQQILSENKIIMAHNEDEEYLANLETIL
RDVKTAFNEASSITLYGDEIILVNCFQPYNHSLYKLNTTVENWFYNMHSETDGSELFK
YLRTLNGFASTLSNDVLRSISKKFLDIITGELPDSMTTVEKFTDIFKNCLENQFEITN
LKILFDELNSFDIPVVLNDLINNQMKPGIFWKKDFISAIKFDGFTSIISLESLHQLLS
IHYRITLQVLLTFVLFDLDTEIFGQHISTLLDLHYKQFLLLNLYRQDKCLLAEVLLKD
SSEFSFGVKFFNYGQLIAYIDSLNSNVYNASITENSFFMTFFRSYIIENTSHKNIRFF
LENVECPFYLRHNEVQEFMFAMTLFSCGNFDQSYEIFQLHDYPEAINDKLPTFLEDLK
SENYHGDSIWKDLLCTFTVPYRHSAFYYQLSLLFDRNNSQEFALKCISKSAEYSLKEI
QIEELQDFKEKQHIHYLNLLIHFRMFEEVLDVLRLGHECLSDTVRTNFLQLLLQEDIY
SRDFFSTLLRLCNAHSDNGELYLRTVDIKIVDSILSQNLRSGDWECFKKLYCFRMLNK
SERAAAEVLYQYILMQADLDVIRKRKCYLMVINVLSSFDSAYDQWILNGSKVVTLTDL
RDELRGL"
gene complement(334412..334915)
/gene="TMA19"
/locus_tag="YKL056C"
/gene_synonym="MMI1"
mRNA complement(334412..334915)
/gene="TMA19"
/locus_tag="YKL056C"
/gene_synonym="MMI1"
/product="Tma19p"
CDS complement(334412..334915)
/gene="TMA19"
/locus_tag="YKL056C"
/gene_synonym="MMI1"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16806052]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:16806052]"
/experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
stress granule [PMID:26777405]"
/experiment="EXISTENCE:mutant phenotype:GO:0002181
cytoplasmic translation [PMID:16702403]"
/experiment="EXISTENCE:mutant phenotype:GO:0010507
negative regulation of autophagy [PMID:31936125]"
/note="Protein that associates with ribosomes; homolog of
translationally controlled tumor protein; green
fluorescent protein (GFP)-fusion protein localizes to the
cytoplasm and relocates to the mitochondrial outer surface
upon oxidative stress; homolog of human TPT1"
/codon_start=1
/product="Tma19p"
/protein_id="DAA09101.1"
/db_xref="SGD:S000001539"
/translation="MIIYKDIFSNDELLSDAYDAKLVDDVIYEADCAMVNVGGDNIDI
GANPSAEGGDDDVEEGAEMVNNVVHSFRLQQTAFDKKSFLTYIKGYMKAVKAKLQETN
PEEVPKFEKGAQTYVKKVIGSFKDWEFFTGESMDPDAMVVMLNYREDGTTPFVAIWKH
GIVEEKI"
gene complement(335321..336157)
/gene="OAR1"
/locus_tag="YKL055C"
mRNA complement(335321..336157)
/gene="OAR1"
/locus_tag="YKL055C"
/product="3-oxoacyl-[acyl-carrier-protein] reductase
(NADPH)"
CDS complement(335321..336157)
/gene="OAR1"
/locus_tag="YKL055C"
/EC_number="1.1.1.100"
/experiment="EXISTENCE:direct assay:GO:0004316
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH)
activity [PMID:19571038]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:24769239]"
/experiment="EXISTENCE:mutant phenotype:GO:0004316
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH)
activity [PMID:9388293]"
/experiment="EXISTENCE:mutant phenotype:GO:0005739
mitochondrion [PMID:9388293]"
/experiment="EXISTENCE:mutant phenotype:GO:0006631 fatty
acid metabolic process [PMID:9388293]"
/experiment="EXISTENCE:mutant phenotype:GO:0009060 aerobic
respiration [PMID:9388293]"
/note="Mitochondrial 3-oxoacyl-[acyl-carrier-protein]
reductase; may comprise a type II mitochondrial fatty acid
synthase along with Mct1p; human homolog CBR4 complements
yeast null mutant"
/codon_start=1
/product="3-oxoacyl-[acyl-carrier-protein] reductase
(NADPH)"
/protein_id="DAA09102.1"
/db_xref="SGD:S000001538"
/translation="MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERT
AIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPC
NKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMM
KSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEP
RNIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTAL
ET"
gene complement(336537..338753)
/gene="DEF1"
/locus_tag="YKL054C"
/gene_synonym="VID31"
mRNA complement(336537..338753)
/gene="DEF1"
/locus_tag="YKL054C"
/gene_synonym="VID31"
/product="DNA damage-responsive RNA polymerase-degradation
factor DEF1"
CDS complement(336537..338753)
/gene="DEF1"
/locus_tag="YKL054C"
/gene_synonym="VID31"
/experiment="EXISTENCE:direct assay:GO:0006511
ubiquitin-dependent protein catabolic process
[PMID:11859374]"
/experiment="EXISTENCE:direct assay:GO:0062058
transcription factor TFIIH holo complex binding
[PMID:29180430]"
/experiment="EXISTENCE:genetic interaction:GO:0006283
transcription-coupled nucleotide-excision repair
[PMID:17537816]"
/experiment="EXISTENCE:mutant phenotype:GO:0000723
telomere maintenance [PMID:15863512]"
/experiment="EXISTENCE:mutant phenotype:GO:0005634 nucleus
[PMID:11859374]"
/experiment="EXISTENCE:mutant phenotype:GO:0006511
ubiquitin-dependent protein catabolic process
[PMID:11859374]"
/experiment="EXISTENCE:mutant phenotype:GO:0006974 DNA
damage response [PMID:11859374]"
/experiment="EXISTENCE:mutant phenotype:GO:0016567 protein
ubiquitination [PMID:24465179]"
/experiment="EXISTENCE:mutant phenotype:GO:0060261
positive regulation of transcription initiation by RNA
polymerase II [PMID:29180430]"
/note="RNAPII degradation factor; forms a complex with
Rad26p in chromatin, enables ubiquitination and
proteolysis of RNAPII present in an elongation complex;
interacts with general transcription factor TFIIH; mutant
is deficient in Zip1p loading onto chromosomes during
meiosis; null mutant is prone to self-diploidization; null
mutation can be functionally complemented by human UBAP2
and UBAP2"
/codon_start=1
/product="DNA damage-responsive RNA polymerase-degradation
factor DEF1"
/protein_id="DAA09103.1"
/db_xref="SGD:S000001537"
/translation="MSTQFRKSNHNSHSSKKLNPALKSKIDTLTELFPDWTSDDLIDI
VQEYDDLETIIDKITSGAVTRWDEVKKPAKKEKYEKKEQQHSYVPQQHLPNPEDDITY
KSSNNSNSFTSTKHNSSNNYTQARNKKKVQTPRAHTTGKHVNLDKGKHVPSKPVSNTT
SWAAAVSVDTKHDVPQDSNDNNNEELEAQGQQAQEKNQEKEQEEQQQQEGHNNKEEHK
QIEQPSLSSKKTTSRTSASQPKKMSWAAIATPKPKAVKKTESPLENVAELKKEISDIK
KDDQKSEASEEKVNEQETSAQEQEEETAEPSEENEDRVPEVDGEEVQEEAEKKEQVKE
EEQTAEELEQEQDNVAAPEEEVTVVEEKVEISAVISEPPEDQANTVPQPQQQSQQPQQ
PQQPQQPQQPQQPQQQQQPQQPQQPQQQLQQQQQQQQQPVQAQAQAQEEQLSQNYYTQ
QQQQQYAQQQHQLQQQYLSQQQQYAQQQQQHPQPQSQQPQSQQSPQSQKQGNNVAAQQ
YYMYQNQFPGYSYPGMFDSQGYAYGQQYQQLAQNNAQTSGNANQYNFQQGYGQAGANT
AAANLTSAAAAAAASPATAHAQPQQQQPYGGSFMPYYAHFYQQSFPYGQPQYGVAGQY
PYQLPKNNYNYYQTQNGQEQQSPNQGVAQHSEDSQQKQSQQQQQQQPQGQPQPEVQMQ
NGQPVNPQQQMQFQQYYQFQQQQQQAAAAAAAAAQQGVPYGYNGYDYNSKNSRGFY"
gene complement(339182..339442)
/gene="MDM35"
/locus_tag="YKL053C-A"
mRNA complement(339182..339442)
/gene="MDM35"
/locus_tag="YKL053C-A"
/product="Mdm35p"
CDS complement(339182..339442)
/gene="MDM35"
/locus_tag="YKL053C-A"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005758
mitochondrial intermembrane space [PMID:17095012]"
/experiment="EXISTENCE:direct assay:GO:0015914
phospholipid transport [PMID:27354379]"
/experiment="EXISTENCE:direct assay:GO:0045332
phospholipid translocation [PMID:26235513]"
/experiment="EXISTENCE:mutant phenotype:GO:0007005
mitochondrion organization [PMID:11907266]"
/experiment="EXISTENCE:mutant phenotype:GO:0033108
mitochondrial respiratory chain complex assembly
[PMID:19703468]"
/note="Mitochondrial intermembrane space protein; forms
complex with Ups2p that transfers phosphatidylserine from
outer membrane to inner membrane for
phosphatidylethanolamine synthesis; mutation affects
mitochondrial distribution and morphology; contains twin
cysteine-x9-cysteine motifs; protein abundance increases
in response to DNA replication stress"
/codon_start=1
/product="Mdm35p"
/protein_id="DAA09104.1"
/db_xref="SGD:S000007243"
/translation="MGNIMSASFAPECTDLKTKYDSCFNEWYSEKFLKGKSVENECSK
QWYAYTTCVNAALVKQGIKPALDEAREEAPFENGGKLKEVDK"
gene complement(339668..340546)
/gene="ASK1"
/locus_tag="YKL052C"
mRNA complement(339668..340546)
/gene="ASK1"
/locus_tag="YKL052C"
/product="Ask1p"
CDS complement(339668..340546)
/gene="ASK1"
/locus_tag="YKL052C"
/experiment="EXISTENCE:direct assay:GO:0008017 microtubule
binding [PMID:15664196|PMID:16777964]"
/experiment="EXISTENCE:direct assay:GO:0031116 positive
regulation of microtubule polymerization [PMID:15664196]"
/experiment="EXISTENCE:direct assay:GO:0042729 DASH
complex [PMID:15640796|PMID:15664196]"
/experiment="EXISTENCE:direct assay:GO:0051010 microtubule
plus-end binding [PMID:17620411|PMID:20479465]"
/experiment="EXISTENCE:direct assay:GO:0051987 positive
regulation of attachment of spindle microtubules to
kinetochore [PMID:20479465|PMID:20479468]"
/note="Essential subunit of the Dam1 complex (aka DASH
complex); couples kinetochores to the force produced by MT
depolymerization thereby aiding in chromosome segregation;
phosphorylated during the cell cycle by cyclin-dependent
kinases; sumoylated in an Mms21p-dependent manner; protein
abundance increases in response to DNA replication stress"
/codon_start=1
/product="Ask1p"
/protein_id="DAA09105.1"
/db_xref="SGD:S000001535"
/translation="MDSASKEETLEKLDQEITVNLQKIDSNLSFCFHKITQDIIPHVA
TYSEICERIMDSTEWLGTMFQETGLVNLQANAAAPVGNAPVKSLVSNNVGIFPTSAEE
ASRQSQTDNGPNEADSAVHVNRDVHSMFNNDSIDDFHTANITSTGQILKLPDSSDEDT
GSEAVPSREQTDLTGEGHGGADDEQDESTIQRQSRKRKISLLLQQQYGSSSSMVPSPI
VPNKMRKQLAHEEHINNDGDNDDENSNNIESSPLKQGHHHPKGQADDNNEGPDEEEST
KEVPKPGTIIHFSTNR"
gene 341312..342373
/gene="SFK1"
/locus_tag="YKL051W"
mRNA 341312..342373
/gene="SFK1"
/locus_tag="YKL051W"
/product="Sfk1p"
CDS 341312..342373
/gene="SFK1"
/locus_tag="YKL051W"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:12015967]"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/experiment="EXISTENCE:genetic interaction:GO:0007033
vacuole organization [PMID:12015967]"
/experiment="EXISTENCE:genetic interaction:GO:0030036
actin cytoskeleton organization [PMID:12015967]"
/experiment="EXISTENCE:genetic interaction:GO:0061093
negative regulation of phospholipid translocation
[PMID:29540528]"
/experiment="EXISTENCE:mutant phenotype:GO:0005886 plasma
membrane [PMID:12015967]"
/experiment="EXISTENCE:mutant phenotype:GO:0061093
negative regulation of phospholipid translocation
[PMID:29540528]"
/note="Protein that regulates phospholipid asymmetry at
plasma membrane; may act to generate normal levels of
PI4P; may act together with or upstream of Stt4p; at least
partially mediates proper localization of Stt4p to the
plasma membrane"
/codon_start=1
/product="Sfk1p"
/protein_id="DAA09106.1"
/db_xref="SGD:S000001534"
/translation="MIQFKSPGNWLFIVPWIAFIPWYGMLIAMLICWASQGHPIYWFM
HSEQFPVYISDIGATNLRPLFISCAGWQGLGYVITVALEFFQRSGYLPFQLKKKDPSI
SDSTSYAEKLHSGKYLMPPYYTKDERNLIFAAFVLGSIGELALLFSSIFSTALYHRVH
IAMVSVFVVFMFLSTCCLIAEYFLMGRHYASVHPLASPHFNPQSSEKSFNQDYNTVDE
LPWYKWKGHVWNKFTISATLKVIWLTLAVVWAICFGAINDRSKSACFEWLLAFWFGII
FMILSADFYLGGRYRQSRYFNHVESFSGYYKYDKALGLYHSEDVLPSDDNAGVIATET
ASSNIYNNSSSNESIQVVV"
gene complement(342852..345620)
/gene="LPX2"
/locus_tag="YKL050C"
mRNA complement(342852..345620)
/gene="LPX2"
/locus_tag="YKL050C"
/product="Lpx2p"
CDS complement(342852..345620)
/gene="LPX2"
/locus_tag="YKL050C"
/experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
[PMID:36164978]"
/note="Peroxisomal matrix-localized lipase; target of
SCFCdc4 ubiquitin ligase complex; peroxisomal, nuclear and
cytosolic localization is dependent on the presence of
oleate; transcription is regulated by Azf1p; LPX2 has a
paralog, EIS1, that arose from the whole genome
duplication"
/codon_start=1
/product="Lpx2p"
/protein_id="DAA09107.1"
/db_xref="SGD:S000001533"
/translation="MSLISALQTTDVESVQTSPEQITERKAVRVSTLQESLHSSEMHR
AAPETPRSISNSVHKLKTIYSTYQQSGQPLSKEAIFRAKQKYGILNTPANYKTLGLGD
SKSESVDLAARLASKRTKVSPDDCVETAIEQKARGEAFKVTFSKIPLTPPEDVPITVN
LGLKGRRDFLTRLAAQKALAFSPSLDNSMKGTSDSSSVKKKRFSGAPIGNEFDANLVN
PQHPAGFKSLDLSKVLDGAERRAISRVNDRLYPQKVNFKNGLQSSDQSGVSKANKEVF
KKGTLEKLEHSAEQFLESHAGNERQRLSDQQYMCAKGAADAVKDLDPKTLEDPDFAAR
EAQKKLYIKQVASPVVLNEAQKLANRKLQDIDSRDTYMLLFGNQAYNKLAVNIALQHY
SVKQEEKKKIYLGGGLWMTPEEVNAVAKKLISPVVNEIDERASRQRDVDKDIERRSRV
LDQEYEDGNSMERAKEQNDGQLLLAMASKQQQEKEAKKAEEGQRYDQFVQKMNIKLQQ
KEKELENARENRENLRNELQERLSKNLSGENDELNDWNDACERDLKNSSIEHYYAVRS
HFDNLGNSERGYDELLEERSKIQVEIERLVASIAEHKTAIHGFGETADAGGAIPAVQK
QKIPTRKDLLDATVNDPLVISAEMAKEEAEMATEECMLKELQVDEMIIIRNIMLRECE
KKLEEEKETAKRSRRGTEESKNNSNFSRDVIMSTPDNNEKVTPIGKSASPKDVVKSRF
LSTYNTGKDIDSSASARSITGVSGVLDDGPKTPTSNKENELIDDEVKSYKVHQAVDGT
GEDSIANKRDKSSRPAANSGGSITIEQFLFNKNADKQGLSKTESVTMKREPVVDQMDS
KKGHDFTHCNDNGRRSFSGFSQGSIENDYSNEVTDDQDDQEGSEIRVRDSNDSNTSPK
ESFFKEVI"
gene complement(346075..346764)
/gene="CSE4"
/locus_tag="YKL049C"
/gene_synonym="CSL2"
mRNA complement(346075..346764)
/gene="CSE4"
/locus_tag="YKL049C"
/gene_synonym="CSL2"
/product="centromeric DNA-binding histone H3-like protein
CSE4"
CDS complement(346075..346764)
/gene="CSE4"
/locus_tag="YKL049C"
/gene_synonym="CSL2"
/experiment="EXISTENCE:direct assay:GO:0000779 condensed
chromosome, centromeric region
[PMID:16207811|PMID:23623551]"
/experiment="EXISTENCE:direct assay:GO:0005729
2-micrometer circle DNA [PMID:16966420]"
/experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
[PMID:36164978]"
/experiment="EXISTENCE:direct assay:GO:0019237 centromeric
DNA binding [PMID:11063678|PMID:23623551]"
/experiment="EXISTENCE:direct assay:GO:0043505 CENP-A
containing nucleosome [PMID:11063678|PMID:19782029]"
/experiment="EXISTENCE:direct assay:GO:0043565
sequence-specific DNA binding [PMID:16966420]"
/experiment="EXISTENCE:genetic interaction:GO:0000779
condensed chromosome, centromeric region [PMID:11063678]"
/experiment="EXISTENCE:mutant phenotype:GO:0000070 mitotic
sister chromatid segregation [PMID:7698647]"
/experiment="EXISTENCE:mutant phenotype:GO:0030543
2-micrometer plasmid partitioning [PMID:16966420]"
/experiment="EXISTENCE:mutant phenotype:GO:0051382
kinetochore assembly [PMID:16207811]"
/experiment="EXISTENCE:mutant phenotype:GO:0061644 protein
localization to CENP-A containing chromatin
[PMID:28980861]"
/note="Centromeric histone H3-like protein; associates
with promoters, accessible chromatin, and RNAPII-bound
regions; Cse4p associates with centromeres, promoting
kinetochore assembly and Sgo1p association with
centromeric chromatin; Ipl1p-dependent phosphorylation
destabilizes defective kinetochores promoting
bi-orientation; phosphorylation by Cdc7p maintains Cse4p
at kinetochores and promotes faithful chromosome
segregation; regulated by multiple E3 ligases; complements
human homolog CENPA mutations"
/codon_start=1
/product="centromeric DNA-binding histone H3-like protein
CSE4"
/protein_id="DAA09108.1"
/db_xref="SGD:S000001532"
/translation="MSSKQQWVSSAIQSDSSGRSLSNVNRLAGDQQSINDRALSLLQR
TRATKNLFPRREERRRYESSKSDLDIETDYEDQAGNLEIETENEEEAEMETEVPAPVR
THSYALDRYVRQKRREKQRKQSLKRVEKKYTPSELALYEIRKYQRSTDLLISKIPFAR
LVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDM
QLARRIRGQFI"
gene complement(347214..349136)
/gene="ELM1"
/locus_tag="YKL048C"
/gene_synonym="LDB9"
mRNA complement(347214..349136)
/gene="ELM1"
/locus_tag="YKL048C"
/gene_synonym="LDB9"
/product="serine/threonine protein kinase ELM1"
CDS complement(347214..349136)
/gene="ELM1"
/locus_tag="YKL048C"
/gene_synonym="LDB9"
/EC_number="2.7.11.1"
/experiment="EXISTENCE:direct assay:GO:0000144 cellular
bud neck septin ring [PMID:27053666]"
/experiment="EXISTENCE:direct assay:GO:0004672 protein
kinase activity [PMID:16319894]"
/experiment="EXISTENCE:direct assay:GO:0004674 protein
serine/threonine kinase activity
[PMID:12847291|PMID:16201971|PMID:9180279]"
/experiment="EXISTENCE:direct assay:GO:0005935 cellular
bud neck [PMID:14562095]"
/experiment="EXISTENCE:mutant phenotype:GO:0000023 maltose
metabolic process [PMID:34140941]"
/experiment="EXISTENCE:mutant phenotype:GO:0000144
cellular bud neck septin ring [PMID:27053666]"
/experiment="EXISTENCE:mutant phenotype:GO:0000281 mitotic
cytokinesis [PMID:10725226]"
/experiment="EXISTENCE:mutant phenotype:GO:0000902 cell
morphogenesis [PMID:16607009|PMID:9427410]"
/experiment="EXISTENCE:mutant phenotype:GO:0000921 septin
ring assembly [PMID:10725226]"
/experiment="EXISTENCE:mutant phenotype:GO:0007117 budding
cell bud growth [PMID:10234786]"
/experiment="EXISTENCE:mutant phenotype:GO:0007124
pseudohyphal growth [PMID:9891070]"
/experiment="EXISTENCE:mutant phenotype:GO:0042149
cellular response to glucose starvation [PMID:15340085]"
/experiment="EXISTENCE:mutant phenotype:GO:1902935 protein
localization to septin ring [PMID:27053666]"
/note="Serine/threonine protein kinase; regulates the
orientation checkpoint, the morphogenesis checkpoint and
the metabolic switch from fermentative to oxidative
metabolism by phosphorylating the activation loop of
Kin4p, Hsl1p and Snf1p respectively; cooperates with Hsl7p
in recruiting Hsl1p to the septin ring, a prerequisite for
subsequent recruitment, phosphorylation, and degradation
of Swe1p; forms part of the bud neck ring; regulates
cytokinesis"
/codon_start=1
/product="serine/threonine protein kinase ELM1"
/protein_id="DAA09109.1"
/db_xref="SGD:S000001531"
/translation="MSPRQLIPTLIPEWAPLSQQSCIREDELDSPPITPTSQTSSFGS
SFSQQKPTYSTIIGENIHTILDEIRPYVKKITVSDQDKKTINQYTLGVSAGSGQFGYV
RKAYSSTLGKVVAVKIIPKKPWNAQQYSVNQVMRQIQLWKSKGKITTNMSGNEAMRLM
NIEKCRWEIFAASRLRNNVHIVRLIECLDSPFSESIWIVTNWCSLGELQWKRDDDEDI
LPQWKKIVISNCSVSTFAKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKL
SDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFK
LDIWSLGVTLYCLLYNELPFFGENEFETYHKIIEVSLSSKINGNTLNDLVIKRLLEKD
VTLRISIQDLVKVLSRDQPIDSRNHSQISSSSVNPVRNEGPVRRFFGRLLTKKGKKKT
SGKGKDKVLVSATSKVTPSIHIDEEPDKECFSTTVLRSSPDSSDYCSSLGEEAIQVTD
FLDTFCRSNESLPNLTVNNDKQNSDMKTDRSESSSHSSLKIPTPIKAMIRLKSSPKEN
GNRTHINCSQDKPSSPLMDRTVGKRTVNNSGARKLAHSSNILNFKAYINSEDSDIRET
VEDVKTYLNFADNGQI"
gene 349463..351013
/gene="ANR2"
/locus_tag="YKL047W"
mRNA 349463..351013
/gene="ANR2"
/locus_tag="YKL047W"
/product="Anr2p"
CDS 349463..351013
/gene="ANR2"
/locus_tag="YKL047W"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005811 lipid
droplet [PMID:24868093]"
/note="hypothetical protein; may have a role in lipid
metabolism, based on localization to lipid droplets;
predicted to be palmitoylated"
/codon_start=1
/product="Anr2p"
/protein_id="DAA09110.1"
/db_xref="SGD:S000001530"
/translation="MNSGGEEPTIKPNVFNITQLLNSNGEKPGIACIFLSKFDMKKGN
IIIWSKSINGAAIDLSNIEFKSLPAGIHEQTDDVVNFVVPKELDVCQTAKTTTYDYGI
AYFKQNSFDIIENDNRIDRSKVQMFSLGVIIDVQNASSDSKKHFYKEIYHAYAANRYS
SYLESLLGQWIRQRDLDKFDIFEKFFDENNQGHMAENSVEVFEHSPKERRHLVEYLPY
WTRKLGPLIFPLWKASLLQSRILILVPQGESFELCNSLAYCVFLISMLPKNLIGNHVS
DEYIKPIFTVSTSDIPFLESFKKGNGYVATTSEEILLYKPEIYDIVVKLTSSSTIEES
PEKEVEILTASGEQNKATPLDLEVYEKLILGELQEDASTNATCRHHEVTEPISWLQFL
IDGFFLLTTAGYLVAPYHLANNFKIPRHVSGPEPNNSEIQIAENLVRYFHRRTSNLYN
DLKDVIQKSENIDSEQPITIAASFLTKLNLDCFSKQDHQFVKDIALKWFQRSIDISNL
PECLGNLC"
gene complement(351275..352624)
/gene="DCW1"
/locus_tag="YKL046C"
mRNA complement(351275..352624)
/gene="DCW1"
/locus_tag="YKL046C"
/product="putative mannan endo-1,6-alpha-mannosidase"
CDS complement(351275..352624)
/gene="DCW1"
/locus_tag="YKL046C"
/EC_number="3.2.1.101"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:14562095|PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:12421307]"
/experiment="EXISTENCE:direct assay:GO:0005933 cellular
bud [PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0009272 fungal-type
cell wall biogenesis [PMID:12421307]"
/experiment="EXISTENCE:genetic interaction:GO:0007117
budding cell bud growth [PMID:15470258]"
/note="Putative mannosidase; GPI-anchored membrane protein
required for cell wall biosynthesis in bud
formation;homologous to Dfg5p"
/codon_start=1
/product="putative mannan endo-1,6-alpha-mannosidase"
/protein_id="DAA09111.1"
/db_xref="SGD:S000001529"
/translation="MLVNKVIGLLGVLFATRFTNAVELDLDNYESLQNATSLIAYGLM
DYYTGNQYGKTVGMFSDPYYWWEAGGAWGCMLDYWFFMDNDTYNDEIIAAMIHQAGDD
NDYIPLNQSTTEGNDDQAFWGIAAMTAAERNFTNPPENEPQWLYLAQAVFNTMALRWD
ADSCGGGLRWQIFVWNSGYDYKNTVSNGALFHIAARLARYTGNQTYVDWAEKVYEWMV
GVNLISNGTYKYVYDGVSIDDNCTKVTSYQWTYNQGLLLAGSAYLYNFTGSDLWHTRT
KEFLNASQVFFHDGIVYEAACQGPNSCNTDQRSFKAYFARFLGVTAQLVPETRNQIMS
WLNTSAIAAAKSCSGGTDGHTCGLNWFNGTWDGMYGLGEQMSALEVMVNTRALDKPAP
YTAENGGSSVGDGAAGTQAQPTNLAPLNITKGSKAGAGIITAVIGISIVACALWLVF"
gene 353493..355079
/gene="PRI2"
/locus_tag="YKL045W"
mRNA 353493..355079
/gene="PRI2"
/locus_tag="YKL045W"
/product="DNA primase subunit PRI2"
CDS 353493..355079
/gene="PRI2"
/locus_tag="YKL045W"
/experiment="EXISTENCE:direct assay:GO:0003697
single-stranded DNA binding [PMID:20404922]"
/experiment="EXISTENCE:direct assay:GO:0003896 DNA primase
activity [PMID:3061469|PMID:3888995]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:15282802]"
/experiment="EXISTENCE:direct assay:GO:0005635 nuclear
envelope [PMID:15282802]"
/experiment="EXISTENCE:direct assay:GO:0005658 alpha DNA
polymerase:primase complex [PMID:3888995|PMID:22593576]"
/experiment="EXISTENCE:direct assay:GO:0006269 DNA
replication, synthesis of RNA primer [PMID:2644256]"
/experiment="EXISTENCE:genetic interaction:GO:0003896 DNA
primase activity [PMID:8436268]"
/experiment="EXISTENCE:mutant phenotype:GO:0003896 DNA
primase activity [PMID:8436268]"
/experiment="EXISTENCE:mutant phenotype:GO:0006260 DNA
replication [PMID:2023935]"
/experiment="EXISTENCE:mutant phenotype:GO:0006302
double-strand break repair [PMID:10025407]"
/note="Subunit of DNA primase; DNA primase is required for
DNA synthesis and double-strand break repair"
/codon_start=1
/product="DNA primase subunit PRI2"
/protein_id="DAA09112.1"
/db_xref="SGD:S000001528"
/translation="MFRQSKRRIASRKNFSSYDDIVKSELDVGNTNAANQIILSSSSS
EEEKKLYARLYESKLSFYDLPPQGEITLEQFEIWAIDRLKILLEIESCLSRNKSIKEI
ETIIKPQFQKLLPFNTESLEDRKKDYYSHFILRLCFCRSKELREKFVRAETFLFKIRF
NMLTSTDQTKFVQSLDLPLLQFISNEEKAELSHQLYQTVSASLQFQLNLNEEHQRKQY
FQQEKFIKLPFENVIELVGNRLVFLKDGYAYLPQFQQLNLLSNEFASKLNQELIKTYQ
YLPRLNEDDRLLPILNHLSSGYTIADFNQQKANQFSENVDDEINAQSVWSEEISSNYP
LCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFN
KEYRYSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRS
MKLTQAQIISVLDSCQKGEYTIACTKVFEMTHNSASADLEIGEQTHIAHPNLYFERSR
QLQKKQQKLEKEKLFNNGNH"
gene 356322..356642
/gene="MMO1"
/locus_tag="YKL044W"
mRNA 356322..356642
/gene="MMO1"
/locus_tag="YKL044W"
/product="Mmo1p"
CDS 356322..356642
/gene="MMO1"
/locus_tag="YKL044W"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:26928762]"
/note="hypothetical protein; SWAT-GFP, seamless-GFP and
mCherry fusion proteins localize to the mitochondria; mRNA
identified as translated by ribosome profiling data; MMO1
is a non-essential gene"
/codon_start=1
/product="Mmo1p"
/protein_id="DAA35123.1"
/db_xref="SGD:S000001527"
/translation="MGYVIMTFSSARMSERRARIIYIWMHLSAYKINFPFVQFPTFFS
LFRLQKKAAILIKNPSPFFLFFLFPYRKNSTARTIHQINQAVALVLLCVSHHLTYLPS
VPSL"
gene 356748..357848
/gene="PHD1"
/locus_tag="YKL043W"
mRNA 356748..357848
/gene="PHD1"
/locus_tag="YKL043W"
/product="Phd1p"
CDS 356748..357848
/gene="PHD1"
/locus_tag="YKL043W"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:8114741]"
/experiment="EXISTENCE:direct assay:GO:0043565
sequence-specific DNA binding
[PMID:19111667|PMID:19158363]"
/experiment="EXISTENCE:mutant phenotype:GO:0003700
DNA-binding transcription factor activity [PMID:16449570]"
/experiment="EXISTENCE:mutant phenotype:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:8114741]"
/experiment="EXISTENCE:mutant phenotype:GO:2000222
positive regulation of pseudohyphal growth [PMID:8114741]"
/note="Transcriptional activator that enhances
pseudohyphal growth; physically interacts with the
Tup1-Cyc8 complex and recruits Tup1p to its targets;
regulates expression of FLO11, an adhesin required for
pseudohyphal filament formation; similar to StuA, an A.
nidulans developmental regulator; potential Cdc28p
substrate; PHD1 has a paralog, SOK2, that arose from the
whole genome duplication"
/codon_start=1
/product="Phd1p"
/protein_id="DAA09113.1"
/db_xref="SGD:S000001526"
/translation="MYHVPEMRLHYPLVNTQSNAAITPTRSYDNTLPSFNELSHQSTI
NLPFVQRETPNAYANVAQLATSPTQAKSGYYCRYYAVPFPTYPQQPQSPYQQAVLPYA
TIPNSNFQPSSFPVMAVMPPEVQFDGSFLNTLHPHTELPPIIQNTNDTSVARPNNLKS
IAAASPTVTATTRTPGVSSTSVLKPRVITTMWEDENTICYQVEANGISVVRRADNNMI
NGTKLLNVTKMTRGRRDGILRSEKVREVVKIGSMHLKGVWIPFERAYILAQREQILDH
LYPLFVKDIESIVDARKPSNKASLTPKSSPAPIKQEPSDNKHEIATEIKPKSIDALSN
GASTQGAGELPHLKINHIDTEAQTSRAKNELS"
gene 358475..359566
/gene="SPC42"
/locus_tag="YKL042W"
mRNA 358475..359566
/gene="SPC42"
/locus_tag="YKL042W"
/product="Spc42p"
CDS 358475..359566
/gene="SPC42"
/locus_tag="YKL042W"
/experiment="EXISTENCE:direct assay:GO:0005821
intermediate layer of spindle pole body [PMID:9215630]"
/experiment="EXISTENCE:direct assay:GO:0005823 central
plaque of spindle pole body [PMID:9215630]"
/experiment="EXISTENCE:mutant phenotype:GO:0005200
structural constituent of cytoskeleton [PMID:9215630]"
/experiment="EXISTENCE:mutant phenotype:GO:0030474 spindle
pole body duplication [PMID:9153752]"
/note="Central plaque component of spindle pole body
(SPB); involved in SPB duplication, may facilitate
attachment of the SPB to the nuclear membrane"
/codon_start=1
/product="Spc42p"
/protein_id="DAA09114.1"
/db_xref="SGD:S000001525"
/translation="MNGSPTPKRYSSKSSRLYDDYYNIPYQYSNPTPMNRDYNDVGSR
INADKLVPEEYKRNTEFINKAVQQNKELNFKLREKQNEIFELKKIAETLRSKLEKYVD
ITKKLEDQNLNLQIKISDLEKKLSDANSTFKEMRFPKVKDPMVDDDPVSENYDQINVP
KHRAPDATGNPRTTNKVSNTSDQDSRLKAIERTLSVLTNYVMRSEDGNNDRMSPLPSP
LNTILPINNRLNFQEPKRYNPTVKVNPSDDDIMMYESAELKRVEEEIEELKRKILVRK
KHDLRKLSLNNQLQELQSMMDGDDNIKLDNVSKHNHATHRHSSQSSRDYSPSSDACLE
CSNDLYEKNRVKPENNMSETFATPTPNNR"
gene 360143..360817
/gene="VPS24"
/locus_tag="YKL041W"
/gene_synonym="DID3"
/gene_synonym="VPL26"
mRNA 360143..360817
/gene="VPS24"
/locus_tag="YKL041W"
/gene_synonym="DID3"
/gene_synonym="VPL26"
/product="ESCRT-III subunit protein VPS24"
CDS 360143..360817
/gene="VPS24"
/locus_tag="YKL041W"
/gene_synonym="DID3"
/gene_synonym="VPL26"
/experiment="EXISTENCE:direct assay:GO:0000815 ESCRT III
complex [PMID:12194857]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:9606181]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:mutant phenotype:GO:0045324 late
endosome to vacuole transport [PMID:9606181]"
/experiment="EXISTENCE:mutant phenotype:GO:0070676
intralumenal vesicle formation [PMID:19234443]"
/experiment="EXISTENCE:mutant phenotype:GO:1904669 ATP
export [PMID:26585826]"
/note="One of four subunits of the ESCRT-III complex;
forms an endosomal sorting complex required for transport
III (ESCRT-III) subcomplex with Did4p; involved in the
sorting of transmembrane proteins into the multivesicular
body (MVB) pathway"
/codon_start=1
/product="ESCRT-III subunit protein VPS24"
/protein_id="DAA09115.1"
/db_xref="SGD:S000001524"
/translation="MDYIKKAIWGPDPKEQQRRIRSVLRKNGRNIEKSLRELTVLQNK
TQQLIKKSAKKNDVRTVRLYAKELYQINKQYDRMYTSRAQLDSVRMKIDEAIRMNTLS
NQMADSAGLMREVNSLVRLPQLRNTMIELEKELMKSGIISEMVDDTMESVGDVGEEMD
EAVDEEVNKIVEQYTNEKFKNVDQVPTVELAANEEEQEIPDEKVDEEADRMVNEMRER
LRALQN"
gene complement(361058..361828)
/gene="NFU1"
/locus_tag="YKL040C"
/gene_synonym="NUB1"
mRNA complement(361058..361828)
/gene="NFU1"
/locus_tag="YKL040C"
/gene_synonym="NUB1"
/product="Nfu1p"
CDS complement(361058..361828)
/gene="NFU1"
/locus_tag="YKL040C"
/gene_synonym="NUB1"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005759
mitochondrial matrix [PMID:10468587]"
/experiment="EXISTENCE:genetic interaction:GO:0106035
protein maturation by [4Fe-4S] cluster transfer
[PMID:27532773]"
/experiment="EXISTENCE:mutant phenotype:GO:0016226
iron-sulfur cluster assembly
[PMID:10468587|PMID:10588895]"
/experiment="EXISTENCE:mutant phenotype:GO:0097428 protein
maturation by iron-sulfur cluster transfer
[PMID:12065597]"
/experiment="EXISTENCE:mutant phenotype:GO:0106035 protein
maturation by [4Fe-4S] cluster transfer [PMID:27532773]"
/experiment="EXISTENCE:physical interaction:GO:0106035
protein maturation by [4Fe-4S] cluster transfer
[PMID:27532773]"
/note="Protein involved in Fe-S cluster transfer to
mitochondrial clients; protects [4Fe-4S] clusters from
damage due to oxidative stress; acts along with Bol3 at a
late step in the transfer of [4Fe-4S] clusters from the
ISA complex to client proteins; Fe-S loaded homodimer at
steady state; similar to NifU, a bacterial protein
required for Fe/S cluster maturation; ortholog of the
human NFU1, mutations of which are associated with
Multiple Mitochondria Dysfunctions Syndrome (MMDS1)"
/codon_start=1
/product="Nfu1p"
/protein_id="DAA09116.1"
/db_xref="SGD:S000001523"
/translation="MFKSVAKLGKSPIFYLNSQRLIHIKTLTTPNENALKFLSTDGEM
LQTRGSKSIVIKNTDENLINHSKLAQQIFLQCPGVESLMIGDDFLTINKDRMVHWNSI
KPEIIDLLTKQLAYGEDVISKEFHAVQEEEGEGGYKINMPKFELTEEDEEVSELIEEL
IDTRIRPAILEDGGDIDYRGWDPKTGTVYLRLQGACTSCSSSEVTLKYGIESMLKHYV
DEVKEVIQIMDPEQEIALKEFDKLEKKLESSKNTSHEK"
gene 362622..364193
/gene="PTM1"
/locus_tag="YKL039W"
mRNA 362622..364193
/gene="PTM1"
/locus_tag="YKL039W"
/product="Ptm1p"
CDS 362622..364193
/gene="PTM1"
/locus_tag="YKL039W"
/note="hypothetical protein; copurifies with late Golgi
vesicles containing the v-SNARE Tlg2p; PTM1 has a paralog,
YHL017W, that arose from the whole genome duplication"
/codon_start=1
/product="Ptm1p"
/protein_id="DAA09117.1"
/db_xref="SGD:S000001522"
/translation="MRVYQFCRPFQLFTCFLCYLLVFVKANKEKISQKNYQVCAGMYS
KEDWKGKIDPFISFNLKKISGLSDESDPGLVVAIYDFQDFEHLGVQLPDEEMYYICDD
YAIDIGICEEENRDEFIVQDVVYDPYTSTNRSLANPIMTFSQNEVGLHDTRYPIKETG
FYCVTAFRSSTSTKFNAVVNFRNAYGQLAGTEINKLPLYGLLAVAYVVAMALYSFAFW
KHKHELLPLQKYLLAFFVFLTAETIFVWAYYDLKNEKGDTAGIKVYMVFLSILTAGKV
TFSFFLLLIIALGYGIVYPKLNKTLMRRCQMYGALTYAICIGFLIQSYLTDMEAPSPL
ILITLIPMALALIIFYYMIIRSMTKTVIYLKEQRQIVKLNMYKKLLYIIYASFLSVLA
GSIVSSFIYVGMNTIDMIEKNWRSRFFVTDFWPTLVYFIVFVTIAFLWRPTDTSYMLA
ASQQLPTDPENVADFDLGDLQSFDDQDDASIITGERGIDEDDLNLNFTDDEEGHDNVN
NHSQGHGPVSPSPTK"
gene 364776..364876
/gene="SNR69"
/locus_tag="YNCK0013W"
ncRNA 364776..364876
/ncRNA_class="snoRNA"
/gene="SNR69"
/locus_tag="YNCK0013W"
/product="SNR69"
/experiment="EXISTENCE:curator inference:GO:0005730
nucleolus [PMID:10024243]"
/experiment="EXISTENCE:curator inference:GO:0031428 box
C/D RNP complex [PMID:10024243]"
/experiment="EXISTENCE:mutant phenotype:GO:0030562 rRNA
2'-O-ribose methylation guide activity [PMID:10024243]"
/experiment="EXISTENCE:mutant phenotype:GO:0031167 rRNA
methylation [PMID:10024243]"
/note="C/D box small nucleolar RNA (snoRNA); guides
2'-O-methylation of large subunit (LSU) rRNA at position
C2948"
/db_xref="SGD:S000006460"
gene 365605..369117
/gene="RGT1"
/locus_tag="YKL038W"
mRNA 365605..369117
/gene="RGT1"
/locus_tag="YKL038W"
/product="Rgt1p"
CDS 365605..369117
/gene="RGT1"
/locus_tag="YKL038W"
/experiment="EXISTENCE:direct assay:GO:0000122 negative
regulation of transcription by RNA polymerase II
[PMID:12861007]"
/experiment="EXISTENCE:direct assay:GO:0000978 RNA
polymerase II cis-regulatory region sequence-specific DNA
binding [PMID:12861007|PMID:8887670|PMID:12239282]"
/experiment="EXISTENCE:direct assay:GO:0001228 DNA-binding
transcription activator activity, RNA polymerase
II-specific [PMID:8887670]"
/experiment="EXISTENCE:direct assay:GO:0003677 DNA binding
[PMID:12861007]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:12861007]"
/experiment="EXISTENCE:direct assay:GO:0045944 positive
regulation of transcription by RNA polymerase II
[PMID:8887670]"
/experiment="EXISTENCE:genetic interaction:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:8887670]"
/experiment="EXISTENCE:genetic interaction:GO:0006006
glucose metabolic process [PMID:8013905]"
/note="Glucose-responsive transcription factor; regulates
expression of several glucose transporter (HXT) genes in
response to glucose; binds to promoters and acts both as a
transcriptional activator and repressor; recruits
Tup1p/Cyc8p to target gene promoters; RGT1 has a paralog,
EDS1, that arose from the whole genome duplication"
/codon_start=1
/product="Rgt1p"
/protein_id="DAA09118.1"
/db_xref="SGD:S000001521"
/translation="MNELNTVSTNSSDSTKNGGTSNSPDDMDSAAAASHAIKKRTKAS
RACDQCRKKKIKCDYKDEKGVCSNCQRNGDRCSFDRVPLKRGPSKGYTRSTSHPRTNE
IQDHNNSRSYNTFDNSNNTLNNNTGNSGDNGINSNTVPSTPSRSNSVLLPPLTQYIPQ
AGGIPPSFQNPAIQSTMPAGNIGQQQFWKVPYHEFQHQRKGSIDSLQSDISVRTLNPN
EQLSYNTVQQSPITNKHTNDSGNANGSVTGSGSASGSGGYWSFIRTSGLLAPTDDHNG
EQTRRSSSIPSLLRNTSNSLLLGGQPQLPPPQQQSQPQAHQQKLQQGQNLYSYSQFSQ
QQPYNPSISSFGQFAANGFHSRQGSVASEAMSPSAPAMFTSTSTNPVNVAQQTQRPQG
QQVPQFSSELDGNKRRQSAPVSVTLSTDRLNGNENNNGEINNNNGSNNSGSSKDTSQH
SQESVTTPAALEASSPGSTPQRSTKKRRKSYVSKKTKPKRDSSISITSKDSAHPMTTS
STIAYGQISDVDLIDTYYEFIHVGFPIIPLNKTTLTSDLLLVNTQPISNIHEVNSYVI
LWFRNSLELLVRVALKQKPGGKFFDNIVGVALSPSNDNNKAGFTTATARDDAEKTRRD
SHNEVQDTLEVQSVFIAALNECFQKIVDIHPKFRENNDQISPKIKVIYLSTFILLNYI
LAFVGYDNSFVLGMSVTIFNEFKLYKLLLFPEPDINDVKPPVDEEVSTGNGNTKTSEF
EIGSESAGHMNPSNSPNSMDENISHYSVLFKRLYVLLSVFDSLQSCAFGGPKLLNISI
QGSTERFFSNDLGSKWCLEQSQLRLKSVLQSLKLGELMSELTRNRISMNGNRKPGFDI
TNSSSLLSEYVETQPLSVAQLFCKLLIGKHNFINCLLSLYDSEAGVYSDLTLDLSSKI
ADSLCSLISIILQVLTLILRLNPTNSIDFNYRPPNPPANNPTVQEGPSAMGSSPVAGN
LSAAPPSEGNPDFYKKLLGLKQDTGTILSDLCRGIISPFAIAILHEVYNITELVKQMP
TSLISIMMTATTTQNTQDTKKSQDLVMKLSNSMNEVVQITSVLTMIKPFKIFEHELNK
PIMSLTGGLSSTTRNDVMWPKSGQGLRESSVMKTLLDERRTSGTQPTTAPVAAEEPRL
ENVALENFVSIGWKLLDDSELGWY"
gene 369365..369721
/gene="AIM26"
/locus_tag="YKL037W"
mRNA 369365..369721
/gene="AIM26"
/locus_tag="YKL037W"
/product="Aim26p"
CDS 369365..369721
/gene="AIM26"
/locus_tag="YKL037W"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:19793921]"
/experiment="EXISTENCE:mutant phenotype:GO:0000422
autophagy of mitochondrion [PMID:19793921]"
/experiment="EXISTENCE:mutant phenotype:GO:0016236
macroautophagy [PMID:19793921]"
/note="hypothetical protein; null mutant is viable and
displays elevated frequency of mitochondrial genome loss;
null mutation confers sensitivity to tunicamycin and DTT"
/codon_start=1
/product="Aim26p"
/protein_id="DAA09119.1"
/db_xref="SGD:S000001520"
/translation="MQTMGGEHLLLSQLKGSFFLLLLAYFFRGRSPYYARCYRRLAVT
PGAITIAIAIATDSIPALAKSKVLVSVCSHTDPCTASCNLIPFPRPFSNSLTRFLFCL
GSARFCISFPCFGLSI"
gene 369891..371390
/gene="UGP1"
/locus_tag="YKL035W"
mRNA 369891..371390
/gene="UGP1"
/locus_tag="YKL035W"
/product="UTP glucose-1-phosphate uridylyltransferase"
CDS 369891..371390
/gene="UGP1"
/locus_tag="YKL035W"
/EC_number="2.7.7.9"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:16622836]"
/experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
stress granule [PMID:26777405]"
/experiment="EXISTENCE:direct assay:GO:0070569
uridylyltransferase activity [PMID:22580055]"
/experiment="EXISTENCE:genetic interaction:GO:0005978
glycogen biosynthetic process [PMID:9252577]"
/experiment="EXISTENCE:genetic interaction:GO:0005992
trehalose biosynthetic process [PMID:9252577]"
/experiment="EXISTENCE:genetic interaction:GO:0006011
UDP-glucose metabolic process [PMID:9252577]"
/experiment="EXISTENCE:mutant phenotype:GO:0003983
UTP:glucose-1-phosphate uridylyltransferase activity
[PMID:7588797]"
/experiment="EXISTENCE:mutant phenotype:GO:0005978
glycogen biosynthetic process [PMID:9252577]"
/experiment="EXISTENCE:mutant phenotype:GO:0006011
UDP-glucose metabolic process [PMID:7588797|PMID:9252577]"
/experiment="EXISTENCE:mutant phenotype:GO:0006078
(1->6)-beta-D-glucan biosynthetic process [PMID:17531808]"
/note="UDP-glucose pyrophosphorylase (UGPase); catalyses
the reversible formation of UDP-Glc from glucose
1-phosphate and UTP, involved in a wide variety of
metabolic pathways, expression modulated by Pho85p through
Pho4p; involved in PKA-mediated oxidative stress
resistance and long-term survival in stationary phase;
UGP1 has a paralog, YHL012W, that arose from the whole
genome duplication"
/codon_start=1
/product="UTP glucose-1-phosphate uridylyltransferase"
/protein_id="DAA09120.1"
/db_xref="SGD:S000001518"
/translation="MSTKKHTKTHSTYAFESNTNSVAASQMRNALNKLADSSKLDDAA
RAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKYEIISQQPENVSNLS
KLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDVPLLLMNS
FNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSPLDAWYPPGHGD
LFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGAEYIMELTDKTR
ADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINLKAVKRLIES
SNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHFDGAHGVVVPRSRFLPVKTCSD
LLLVKSDLFRLEHGSLKLDPSRFGPNPLIKLGSHFKKVSGFNARIPHIPKIVELDHLT
ITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVTGNLQILEH"
gene 371829..374105
/gene="TUL1"
/locus_tag="YKL034W"
mRNA 371829..374105
/gene="TUL1"
/locus_tag="YKL034W"
/product="ubiquitin-protein ligase TUL1"
CDS 371829..374105
/gene="TUL1"
/locus_tag="YKL034W"
/EC_number="2.3.2.27"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:11788821]"
/experiment="EXISTENCE:direct assay:GO:0044695 Dsc E3
ubiquitin ligase complex [PMID:22681890]"
/experiment="EXISTENCE:mutant phenotype:GO:0004842
ubiquitin-protein transferase activity [PMID:11788821]"
/experiment="EXISTENCE:mutant phenotype:GO:0016567 protein
ubiquitination [PMID:11788821]"
/experiment="EXISTENCE:mutant phenotype:GO:0043162
ubiquitin-dependent protein catabolic process via the
multivesicular body sorting pathway [PMID:11788821]"
/note="Subunit of the DSC ubiquitin ligase complex;
golgi-localized RING-finger ubiquitin ligase (E3) involved
in sorting polar transmembrane domain containing membrane
proteins to multivesicular bodies for delivery to the
vacuole; proposed involvement in the quality control of
misfolded TMD containing proteins; ortholog of fission
yeast dsc1"
/codon_start=1
/product="ubiquitin-protein ligase TUL1"
/protein_id="DAA09121.1"
/db_xref="SGD:S000001517"
/translation="MEIDGNTLVFIIVILFLFFSSPGGDGVSSQYEFNQLQRLKQQFR
TEHNTFVNMTYTDSFRNITGLKLSYQDMLNNPLQNATYPLPGKDYDRWFPNQNYMVLP
NDVIEAINTEVWNTSNDDASNLFPPNITSTLLGKIDLVSNNKYEKIRMPVPRFYEPAT
DFSEDIPPEGETYWSEWPSYGELHNVSFQHGEIAIQISHMSNLQDNNNYLRRNFINKK
NDRWKLLNLQIDFSDKAEKEKHSIYSKAVYDIQRGRILSISQSSKFHSLFALPHYMSF
QNDYNEKIFNDVKELVDEFWNFTDYTDVMTMKDVQDAYNNANFKCEYLIFLQLEPWNQ
YTRDQIKLIDDELNWPLGRPANLSSLPPINVVSGLLYSPDCGVRLGLHNVKGTRYELK
IMSIRKHLLFGIALFAAQIYLLLTQMHHTNTPSMVNKISFYCFSMINLVDGSLATLYF
VAASVVPELYLPLVISAFSCFILASIFEIRYLISIYASQVNEQNVGIINLLRGNTGTY
DENRPRPAFIPDEGSIGGSLYGRFFFMLIIFTFLILSSTSWPRQLRMVFEYILIFILN
SYWIPQIFRNAVKGIPSRRERARSSIGGNRSQNKMPLLWSFVIGTTIIRSLPVVYVFT
YSSNVFRHHKDVHFVVFLSLWLLFQISILYSQDVLGSRWFLPKHTIPDGYSYFKPLSN
EYISEHGGGTAEHTVDCAICMSDVPIYIEEIPETHKVDQHSYMVTPCNHVFHTSCLEN
WMNYKLQCPVCRSPLPPL"
gene 374505..375215
/locus_tag="YKL033W-A"
mRNA 374505..375215
/locus_tag="YKL033W-A"
/product="putative hydrolase"
CDS 374505..375215
/locus_tag="YKL033W-A"
/EC_number="3.1.3.96"
/experiment="EXISTENCE:direct assay:GO:0008253
5'-nucleotidase activity [PMID:26071590]"
/experiment="EXISTENCE:direct assay:GO:1990738
pseudouridine 5'-phosphatase activity [PMID:26071590]"
/note="hypothetical protein; similar to uncharacterized
proteins from other fungi"
/codon_start=1
/product="putative hydrolase"
/protein_id="DAA09122.1"
/db_xref="SGD:S000007242"
/translation="MTHPVAVKACLFDMDGLLINTEDIYTETLNETLAEFGKGPLTWD
VKIKLQGLPGPEAGKRVIEHYKLPITLDEYDERNVALQSLKWGTCEFLPGALNLLKYL
KLKNIPIALCTSSNKTKFRGKTSHLEEGFDLFDTIVTGDDPRIAKGRGKPFPDIWQLG
LKELNEKFHTDIKPDECIVFEDGIPGVKSAKAFGAHVIWVPHPEAHAVLGDTEALLAG
KGELLSSLEKLEMSKYGL"
gene 375456..378572
/gene="TTI1"
/locus_tag="YKL033W"
mRNA 375456..378572
/gene="TTI1"
/locus_tag="YKL033W"
/product="Tti1p"
CDS 375456..378572
/gene="TTI1"
/locus_tag="YKL033W"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961]"
/note="Subunit of the ASTRA complex, involved in chromatin
remodeling; telomere length regulator involved in the
stability or biogenesis of PIKKs such as TORC1; similar to
S. pombe Tti1p; detected in highly purified mitochondria
in high-throughput studies"
/codon_start=1
/product="Tti1p"
/protein_id="DAA09123.1"
/db_xref="SGD:S000001516"
/translation="MNSDTNAFKDIRISCVELSRIAFLPTESFDPNSLTLLACLKKVE
EKLSAYEDDSLSPKFADYVFVPIASLLKQPALGESQTEYVLLIIFHLLRTCWSSNGKF
SEQLGQQLFPLITFLVSSDKDNQKLITRSDEFKYAGCLVLHQFFKSVRSQRYHKEFFS
NSKPNLLPALGHSVTILLKILEQSPQNNELQFKALASLEVLFQDIISDGEMLSFILPG
NVSVFAKILTKPGRQIHYKVCVRTLEVLAKLLVLVYDDFSLDIKVNKLTDIRELSDTK
LKHEINQSFMFNGPIVLLRTDGKTHRDTSWLTATSGQINIALEAFIPKLLKRNNESID
EALATFVSILLTRCENSLNNCEKVLVSTLVHLERDPMSKLPSHLVKLKEVVNEDLHKL
SDIIRFENADRLSSLSFAITILEKNNERDTMINEVVRCLFESLNESIEPPSLINHKER
IIEQSSQLTTTVNFENLESTNALIALPRLSEDMSLKLKKFTYHMGSLLLERHILNDVV
TELISEQVDSPRTQKIVALWLSTNFIKAMEKQPKEEEVYLQFESDANYSSSMVEEVCL
IVLEFCNELSQDISMEIEGKGIKKSDEFAVCTVLFSIETICAVMREEFQPELIDYIYT
VVDALASPSEAIRYVSQSCALRIADTLYHGSIPNMILSNVDYLVESISSRLNSGMTER
VSQILMVICQLAGYETIENFKDVIETIFKLLDYYHGYSDLCLQFFQLFKIIILEMKKK
YINDDEMILKIANQHISQSTFSPWGMTDFQQVLNILDKETQVKDDITDENDVDFLKDD
NEPSNFQEYFDSKLREPDSDDDEEEREEEVEGSSKEYTDQWTSPIPSDSYKILLQILG
YGERLLTHPSKRLRVQILIVMRLIFPLLSTQHNLLIREVASTWDSIIQCVLCSDYSIV
QPACSCVEQMIKYSGDFVAKRFIELWQKLCQDSFILKELRIDPTVHNHEKKSISKHVK
FPPVTENALVSMVHMVLEGVKITEYLISEAVLEQIIYCCIQVVPVEKISSMSLIVGDI
VWKIRNIN"
gene 379680..379753
/locus_tag="YNCK0014W"
tRNA 379680..379753
/locus_tag="YNCK0014W"
/product="tRNA-Val"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006761"
gene complement(380065..381858)
/gene="IXR1"
/locus_tag="YKL032C"
/gene_synonym="ORD1"
mRNA complement(380065..381858)
/gene="IXR1"
/locus_tag="YKL032C"
/gene_synonym="ORD1"
/product="DNA-binding transcription repressor IXR1"
CDS complement(380065..381858)
/gene="IXR1"
/locus_tag="YKL032C"
/gene_synonym="ORD1"
/experiment="EXISTENCE:direct assay:GO:0000785 chromatin
[PMID:19807692]"
/experiment="EXISTENCE:direct assay:GO:0001046 core
promoter sequence-specific DNA binding [PMID:29449612]"
/experiment="EXISTENCE:direct assay:GO:0003684 damaged DNA
binding [PMID:8634251]"
/experiment="EXISTENCE:direct assay:GO:0043565
sequence-specific DNA binding
[PMID:11115121|PMID:19807692]"
/experiment="EXISTENCE:genetic interaction:GO:0071456
cellular response to hypoxia [PMID:19807692]"
/experiment="EXISTENCE:genetic interaction:GO:2000819
regulation of nucleotide-excision repair [PMID:8538651]"
/experiment="EXISTENCE:mutant phenotype:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:11115121]"
/experiment="EXISTENCE:mutant phenotype:GO:0071456
cellular response to hypoxia [PMID:19807692]"
/experiment="EXISTENCE:mutant phenotype:GO:0090069
regulation of ribosome biogenesis [PMID:29449612]"
/note="Transcriptional repressor that regulates hypoxic
genes during normoxia; involved in the aerobic repression
of genes such as COX5b, TIR1, and HEM13; binds DNA
intrastrand cross-links formed by cisplatin; HMG (high
mobility group box) domain containing protein which binds
and bends cisplatin-modified DNA, blocking excision
repair; IXR1 has a paralog, ABF2, that arose from the
whole genome duplication"
/codon_start=1
/product="DNA-binding transcription repressor IXR1"
/protein_id="DAA09124.1"
/db_xref="SGD:S000001515"
/translation="MNTGISPKQDDASNSNLLNIGQDHSLQYQGLEHNDSQYRDASHQ
TPHQYLNQFQAQPQQQQQQQQQQQQQQQQAPYQGHFQQSPQQQQQNVYYPLPPQSLTQ
PTSQSQQQQQQQQQQQYANSNSNSNNNVNVNALPQDFGYMQQTGSGQNYPTINQQQFS
EFYNSFLSHLTQKQTNPSVTGTGASSNNNSNNNNVSSGNNSTSSNPAQLAASQLNPAT
AAAAAANNAAGPASYLSQLPQVQRYYPNNMNALSSLLDPSSAGNAAGNANTATHPGLL
PPNLQPQLTHHQQQMQQQLQLQQQQQLQQQQQLQQQHQLQQQQQLQQQHHHLQQQQQQ
QQHPVVKKLSSTQSRIERRKQLKKQGPKRPSSAYFLFSMSIRNELLQQFPEAKVPELS
KLASARWKELTDDQKKPFYEEFRTNWEKYRVVRDAYEKTLPPKRPSGPFIQFTQEIRP
TVVKENPDKGLIEITKIIGERWRELDPAKKAEYTETYKKRLKEWESCYPDENDPNGNP
TGHSHKAMNMNLNMDTKIMENQDSIEHITANAIDSVTGSNSNSTNPNTPVSPPISLQQ
QPLQQQQQQQQQQQHMLLADPTTNGSIIKNE"
gene complement(382716..384725)
/gene="MAE1"
/locus_tag="YKL029C"
mRNA complement(382716..384725)
/gene="MAE1"
/locus_tag="YKL029C"
/product="malate dehydrogenase
(oxaloacetate-decarboxylating)"
CDS complement(382716..384725)
/gene="MAE1"
/locus_tag="YKL029C"
/EC_number="1.1.1.38"
/experiment="EXISTENCE:direct assay:GO:0004470 malic
enzyme activity [PMID:9603875]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion
[PMID:14576278|PMID:16823961|PMID:24769239|PMID:9603875]"
/experiment="EXISTENCE:mutant phenotype:GO:0006090
pyruvate metabolic process [PMID:9603875]"
/experiment="EXISTENCE:mutant phenotype:GO:0006520 amino
acid metabolic process [PMID:9603875]"
/note="Mitochondrial malic enzyme; catalyzes the oxidative
decarboxylation of malate to pyruvate, which is a key
intermediate in sugar metabolism and a precursor for
synthesis of several amino acids"
/codon_start=1
/product="malate dehydrogenase
(oxaloacetate-decarboxylating)"
/protein_id="DAA09125.1"
/db_xref="SGD:S000001512"
/translation="MLRTRLSVSVAARSQLTRSLTASRTAPLRRWPIQQSRLYSSNTR
SHKATTTRENTFQKPYSDEEVTKTPVGSRARKIFEAPHPHATRLTVEGAIECPLESFQ
LLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFM
TSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSI
ECRLATYGGDKDVDYIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLP
VCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKKVYPSAVLHFEDFGV
KNARRLLEKYRYELPSFNDDIQGTGAVVMASLIAALKHTNRDLKDTRVLIYGAGSAGL
GIADQIVNHMVTHGVDKEEARKKIFLMDRRGLILQSYEANSTPAQHVYAKSDAEWAGI
NTRSLHDVVENVKPTCLVGCSTQAGAFTQDVVEEMHKHNPRPIIFPLSNPTRLHEAVP
ADLMKWTNNNALVATGSPFPPVDGYRISENNNCYSFPGIGLGAVLSRATTITDKMISA
AVDQLAELSPLREGDSRPGLLPGLDTITNTSARLATAVILQALEEGTARIEQEQVPGG
APGETVKVPRDFDECLQWVKAQMWEPVYRPMIKVQHDPSVHTNQL"
gene 385758..387206
/gene="TFA1"
/locus_tag="YKL028W"
mRNA 385758..387206
/gene="TFA1"
/locus_tag="YKL028W"
/product="transcription factor TFIIE subunit TFA1"
CDS 385758..387206
/gene="TFA1"
/locus_tag="YKL028W"
/experiment="EXISTENCE:direct assay:GO:0000993 RNA
polymerase II complex binding [PMID:8702741]"
/experiment="EXISTENCE:direct assay:GO:0001097 TFIIH-class
transcription factor complex binding [PMID:8702741]"
/experiment="EXISTENCE:direct assay:GO:0001113
transcription open complex formation at RNA polymerase II
promoter [PMID:10973956]"
/experiment="EXISTENCE:direct assay:GO:0003697
single-stranded DNA binding [PMID:9271406]"
/experiment="EXISTENCE:direct assay:GO:0005673
transcription factor TFIIE complex
[PMID:1429681|PMID:7961670]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0006366
transcription by RNA polymerase II
[PMID:1331084|PMID:1429681|PMID:7961670]"
/experiment="EXISTENCE:direct assay:GO:0097550
transcription preinitiation complex [PMID:22751016]"
/experiment="EXISTENCE:genetic interaction:GO:0001113
transcription open complex formation at RNA polymerase II
promoter [PMID:10973956]"
/experiment="EXISTENCE:mutant phenotype:GO:0006366
transcription by RNA polymerase II
[PMID:9188494|PMID:9271406]"
/experiment="EXISTENCE:physical interaction:GO:0000993 RNA
polymerase II complex binding [PMID:11779853]"
/note="TFIIE large subunit; involved in recruitment of RNA
polymerase II to the promoter, activation of TFIIH, and
promoter opening"
/codon_start=1
/product="transcription factor TFIIE subunit TFA1"
/protein_id="DAA09126.1"
/db_xref="SGD:S000001511"
/translation="MDRPIDDIVKNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLK
QLLSINKTELGPLIARLRSDRLISIHKQREYPPNSKSVERVYYYVKYPHAIDAIKWKV
HQVVQRLKDDLDKNSEPNGYMCPICLTKYTQLEAVQLLNFDRTEFLCSLCDEPLVEDD
SGKKNKEKQDKLNRLMDQIQPIIDSLKKIDDSRIEENTFEIALARLIPPQNQSHAAYT
YNPKKGSTMFRPGDSAPLPNLMGTALGNDSSRRAGANSQATLHINITTASDEVAQREL
QERQAEEKRKQNAVPEWHKQSTIGKTALGRLDNEEEFDPVVTASAMDSINPDNEPAQE
TSYQNNRTLTEQEMEERENEKTLNDYYAALAKKQAKLNKEEEEEEEEEEDEEEEEEEE
MEDVMDDNDETARENALEDEFEDVTDTAGTAKTESNTSNDVKQESINDKTEDAVNATA
TASGPSANAKPNDGDDDDDDDDDEMDIEFEDV"
gene 387562..388905
/gene="TCD2"
/locus_tag="YKL027W"
mRNA 387562..388905
/gene="TCD2"
/locus_tag="YKL027W"
/product="tRNA threonylcarbamoyladenosine dehydratase"
CDS 387562..388905
/gene="TCD2"
/locus_tag="YKL027W"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion
[PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005741
mitochondrial outer membrane [PMID:16407407]"
/experiment="EXISTENCE:mutant phenotype:GO:0061503 tRNA
threonylcarbamoyladenosine dehydratase [PMID:23242255]"
/experiment="EXISTENCE:mutant phenotype:GO:0061504 cyclic
threonylcarbamoyladenosine biosynthetic process
[PMID:23242255]"
/note="tRNA threonylcarbamoyladenosine dehydratase;
required for the ct6A tRNA base modification, where an
adenosine at position 37 is modified to form a cyclized
active ester with an oxazolone ring; localized to the
mitochondrial outer membrane; TCD2 has a paralog, TCD1,
that arose from the whole genome duplication"
/codon_start=1
/product="tRNA threonylcarbamoyladenosine dehydratase"
/protein_id="DAA09127.1"
/db_xref="SGD:S000001510"
/translation="MVEKDTWKLITATALFTVAVTTITDYAWTSWQAQKQVIAQQKNK
NKGGQTKSDTDKYHQYDEQFIRQSLKNNVEFLGEDTIEKLSNQYVVVVGAGGVGSWVV
NSLVRSGCRKIRVVDFDQVSLSSLNRHSCAILNDVGTPKVECLRRHMREIAPWCEIDP
INELWTLQNGERLTLGNGTPDFIVDCIDNIDTKVDLLEFAYNHGIKVISSMGASAKSD
PTKLNVGDLATTEEDPLARVVRRKLKKRGILSGIPVVFSAEKPDPKKAKLLPLPDEEY
ERGKVDELSALKDFRVRILPVLGTMPSLFGLTITTWILSNISDKPLEPVEGKNRIKVY
DGIYQSLAGQMSRVGIPSQRIPLALKDVSYLVEEVFKGKSPISGISTRLTLTKWDPSK
PISLQNVVVLTKNEQKVHEDRVLKGKESLQDVYDAKVLKLVSQRFREEAYYSQFR"
rep_origin 388970..389264
/note="ARS1112; Autonomously Replicating Sequence"
/db_xref="SGD:S000118404"
gene complement(389380..389883)
/gene="GPX1"
/locus_tag="YKL026C"
mRNA complement(389380..389883)
/gene="GPX1"
/locus_tag="YKL026C"
/product="glutathione peroxidase GPX1"
CDS complement(389380..389883)
/gene="GPX1"
/locus_tag="YKL026C"
/EC_number="1.11.1.9"
/EC_number="1.11.1.24"
/experiment="EXISTENCE:direct assay:GO:0005782 peroxisomal
matrix [PMID:22659048]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0047066
phospholipid-hydroperoxide glutathione peroxidase activity
[PMID:11445588]"
/experiment="EXISTENCE:mutant phenotype:GO:0004602
glutathione peroxidase activity [PMID:10480913]"
/experiment="EXISTENCE:mutant phenotype:GO:0007031
peroxisome organization [PMID:22659048]"
/experiment="EXISTENCE:mutant phenotype:GO:0047066
phospholipid-hydroperoxide glutathione peroxidase activity
[PMID:11445588]"
/note="Phospholipid hydroperoxide glutathione peroxidase;
induced by glucose starvation that protects cells from
phospholipid hydroperoxides and nonphospholipid peroxides
during oxidative stress; glutathione peroxidase activity
is neuroprotective in models of Huntington's disease; GPX1
has a paralog, HYR1, that arose from the whole genome
duplication"
/codon_start=1
/product="glutathione peroxidase GPX1"
/protein_id="DAA09128.1"
/db_xref="SGD:S000001509"
/translation="MQEFYSFSPIDENGNPFPFNSLRNKVVLIVNVASHCAFTPQYKE
LEYLYEKYKSHGLVIVAFPCGQFGNQEFEKDKEINKFCQDKYGVTFPILHKIRCNGQK
QDPVYKFLKNSVSGKSGIKMIKWNFEKFVVDRNGKVVKRFSCMTRPLELCPIIEELLN
QPPEEQI"
gene complement(390240..392279)
/gene="PAN3"
/locus_tag="YKL025C"
/gene_synonym="ECM35"
mRNA complement(390240..392279)
/gene="PAN3"
/locus_tag="YKL025C"
/gene_synonym="ECM35"
/product="Pan3p"
CDS complement(390240..392279)
/gene="PAN3"
/locus_tag="YKL025C"
/gene_synonym="ECM35"
/experiment="EXISTENCE:direct assay:GO:0000289
nuclear-transcribed mRNA poly(A) tail shortening
[PMID:8816488]"
/experiment="EXISTENCE:direct assay:GO:0003723 RNA binding
[PMID:24872509]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0006281 DNA repair
[PMID:11953437]"
/experiment="EXISTENCE:direct assay:GO:0008143 poly(A)
binding [PMID:24872509]"
/experiment="EXISTENCE:direct assay:GO:0031251 PAN complex
[PMID:8816488]"
/experiment="EXISTENCE:genetic interaction:GO:0006301
postreplication repair [PMID:11953437]"
/experiment="EXISTENCE:mutant phenotype:GO:0000289
nuclear-transcribed mRNA poly(A) tail shortening
[PMID:8816488]"
/experiment="EXISTENCE:mutant phenotype:GO:0003723 RNA
binding [PMID:24872509]"
/experiment="EXISTENCE:mutant phenotype:GO:0008143 poly(A)
binding [PMID:24872509]"
/experiment="EXISTENCE:physical interaction:GO:0006301
postreplication repair [PMID:11953437]"
/note="Essential subunit of the Pan2p-Pan3p
poly(A)-ribonuclease complex; poly (A) mRNA binding
subunit which recruits mRNA to the complex; the
Pan2p-Pan3p complex controls poly(A) tail length and
regulates the stoichiometry and activity of
postreplication repair complexes"
/codon_start=1
/product="Pan3p"
/protein_id="DAA09129.1"
/db_xref="SGD:S000001508"
/translation="MDKINPDWAKDIPCRNITIYGYCKKEKEGCPFKHSDNTTATTIN
DVPPPIDVGEATTPTMTSVPKFNAKVSASFTPMTVGSDSLTTVTNTTSAATNATGNIA
MAATSATASTVNPMINPIVNSSLVNNNNNNSNISISIPTTASSSNYDPFNAPIFTPSS
TSSIHTNANAHSFPFPSIANSGGININATDDNSNNMSMANNVPPPMQPPPIESSNLKY
PRIYPPPHSLLQYHLYAPEQPSSLKSLLKPNERSADQLFIPNNIREDLTKKNLSILQV
FPSSGKVIPSIVQDYFNLVPLNFNNNDFLNKTTLFKVFSNYDGKAYVLKRLPNIDKSM
NPNKISKIYQIWSKINCTNLIKFRDIFQTTKFGDLSICLVFDYYPNSLSLYDYHFVNF
PKFPITNNYLWIYLVQLTNVINSIHSQNLSIGNTLNWRKVLITGDPGRIKLSHCNFMD
LLFNDDTDTVVSSGGSTIEGQQQLDYKYLGELLFNLSINIENSNNNTAPKEYRLEEIT
PQSIDDMRQIDDKFKDVLKYLISDNGDSKKSIHDLTSHFYDKMFMVLESSQTYTEYME
SVLSRELENGRLFRLVNKLNCIFGRIESRIDINWSESGTKFPIILFYDYVFHQVDSNG
KPIMDLTHVLRCLNKLDAGIQEKLMLVTPDELNCIIISYKELKDLIESTFRSITQ"
gene complement(392526..393140)
/gene="URA6"
/locus_tag="YKL024C"
/gene_synonym="SOC8"
mRNA complement(392526..393140)
/gene="URA6"
/locus_tag="YKL024C"
/gene_synonym="SOC8"
/product="bifunctional uridylate/adenylate kinase"
CDS complement(392526..393140)
/gene="URA6"
/locus_tag="YKL024C"
/gene_synonym="SOC8"
/EC_number="2.7.4.14"
/experiment="EXISTENCE:direct assay:GO:0004017 adenylate
kinase activity [PMID:1333436]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:8391780]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:8391780]"
/experiment="EXISTENCE:direct assay:GO:0006139
nucleobase-containing compound metabolic process
[PMID:2549068]"
/experiment="EXISTENCE:direct assay:GO:0006207 'de novo'
pyrimidine nucleobase biosynthetic process [PMID:8391780]"
/experiment="EXISTENCE:direct assay:GO:0009041 UMP/dUMP
kinase activity [PMID:1655742|PMID:2549068]"
/experiment="EXISTENCE:genetic interaction:GO:0004017
adenylate kinase activity [PMID:1333436]"
/experiment="EXISTENCE:mutant phenotype:GO:0009041
UMP/dUMP kinase activity [PMID:1655742]"
/note="Uridylate kinase; catalyzes the seventh enzymatic
step in the de novo biosynthesis of pyrimidines,
converting uridine monophosphate (UMP) into
uridine-5'-diphosphate (UDP)"
/codon_start=1
/product="bifunctional uridylate/adenylate kinase"
/protein_id="DAA09130.1"
/db_xref="SGD:S000001507"
/translation="MTAATTSQPAFSPDQVSVIFVLGGPGAGKGTQCEKLVKDYSFVH
LSAGDLLRAEQGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLI
DGFPRKMDQAISFERDIVESKFILFFDCPEDIMLERLLERGKTSGRSDDNIESIKKRF
NTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDVQDAIRDSL"
gene complement(393146..393373)
/gene="MIN9"
/locus_tag="YKL023C-A"
mRNA complement(393146..393373)
/gene="MIN9"
/locus_tag="YKL023C-A"
/product="Min9p"
CDS complement(393146..393373)
/gene="MIN9"
/locus_tag="YKL023C-A"
/note="Mitochondrial hypothetical protein"
/codon_start=1
/product="Min9p"
/protein_id="DAA09131.1"
/db_xref="SGD:S000113559"
/translation="MNPRYRFILRFYSSKKPTFHNTAPSKTNVNVPRANKSQSKGKHK
GKLLVLVGTLALVTSVISVNYQKNEPVEFLE"
gene 393721..394554
/gene="SKA1"
/locus_tag="YKL023W"
mRNA 393721..394554
/gene="SKA1"
/locus_tag="YKL023W"
/product="Ska1p"
CDS 393721..394554
/gene="SKA1"
/locus_tag="YKL023W"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:mutant phenotype:GO:0034427
nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5' [PMID:31304628]"
/note="SKI complex-associated protein; involved in 3'-5'
degradation of long 3'UTR-containing mRNA, poorly
translated mRNA, and other RNA regions devoid of
ribosomes; proposed to assist the cytoplasmic exosome in a
Ska1-SKI complex when a direct interaction between the
ribosome and the SKI complex is absent"
/codon_start=1
/product="Ska1p"
/protein_id="DAA09132.2"
/db_xref="SGD:S000001506"
/translation="MNKEELLGFLLDDSIDSQKRCVTDQQAYSNWLKNDNDERTAHEE
SSSQSTIAALNKKKQTEAAQEDIEELLNGLEGIIGGADPRNLKSKSKRKTKKGGSKPR
EENVNTEKHIVMLEVEDFSDMSTHEDVNGASPSPNLDRSKKNEKRRKNAKELSYDELK
DKLEVTTRKSRLECKDLKKKVHGLERRNLELEQRLEELKIENQTLIEINNKLLKNTNE
DEINKSQRNKEKDRKRRERRTARRKDERKQEKKQEKKQDNKTSQSFPSSTDMNGQPIE
F"
gene complement(394726..397248)
/gene="CDC16"
/locus_tag="YKL022C"
mRNA complement(394726..397248)
/gene="CDC16"
/locus_tag="YKL022C"
/product="anaphase promoting complex subunit CDC16"
CDS complement(394726..397248)
/gene="CDC16"
/locus_tag="YKL022C"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:22932476]"
/experiment="EXISTENCE:direct assay:GO:0005680
anaphase-promoting complex [PMID:9469814]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:22932476]"
/experiment="EXISTENCE:direct assay:GO:0016567 protein
ubiquitination [PMID:16481473]"
/experiment="EXISTENCE:direct assay:GO:0031145
anaphase-promoting complex-dependent catabolic process
[PMID:8895471]"
/experiment="EXISTENCE:mutant phenotype:GO:0016567 protein
ubiquitination [PMID:16481473]"
/experiment="EXISTENCE:mutant phenotype:GO:0031145
anaphase-promoting complex-dependent catabolic process
[PMID:16481473]"
/experiment="EXISTENCE:mutant phenotype:GO:0032297
negative regulation of DNA-templated DNA replication
initiation [PMID:9660930]"
/experiment="EXISTENCE:mutant phenotype:GO:0061630
ubiquitin protein ligase activity [PMID:16481473]"
/experiment="EXISTENCE:physical interaction:GO:0005515
protein binding [PMID:29883473]"
/note="Subunit of the anaphase-promoting complex/cyclosome
(APC/C); which is a ubiquitin-protein ligase required for
degradation of anaphase inhibitors, including mitotic
cyclins, during the metaphase/anaphase transition;
required for sporulation; relocalizes to the cytosol in
response to hypoxia"
/codon_start=1
/product="anaphase promoting complex subunit CDC16"
/protein_id="DAA09133.1"
/db_xref="SGD:S000001505"
/translation="MKFCLYCCHCYIVICGKATHYYKSSKATSNLKSSNRVLMRNPMS
PSEQHSQHNSTLAASPFVSNVSAARTQQSLPTDAQNDRLQQPWNRTNTATSPYQSLAN
SPLIQKLQANIMTPHQPSANSNSNSNSITGNVVNDNNLLASMSKNSMFGSTIPSTLRK
VSLQREYKDSVDGVVRDEDNDEDVHNNGDAAANANNDRESKLGHNGPLTTTTLTTTTT
ATQLDVSELSAIERLRLWRFDALMQHMYRTAEYIADKVYNISNDPDDAFWLGQVYYNN
NQYVRAVELITRNNLDGVNILCRYLLGLSFVKLQRFDDALDVIGEYNPFSEDPSTTAA
NTMSNNGNNSNTSQPVTDGGIKMESSLCFLRGKIYFAQNNFNKARDAFREAILVDIKN
FEAFEMLLSKNLLTPQEEWDLFDSLDFKEFGEDKEIMKNLYKINLSKYINTEDITKSN
EILAKDYKLADNVDVVRSKVDICYTQCKFNECLELCETVLENDEFNTNILPAYIGCLY
ELSNKNKLFLLSHRLAETFPKSAITWFSVATYYMSLDRISEAQKYYSKSSILDPSFAA
AWLGFAHTYALEGEQDQALTAYSTASRFFPGMHLPKLFLGMQFMAMNSLNLAESYFVL
AYDICPNDPLVLNEMGVMYFKKNEFVKAKKYLKKALEVVKDLDPSSRTTISIQLNLGH
TYRKLNENEIAIKCFRCVLEKNDKNSEIHCSLGYLYLKTKKLQKAIDHLHKSLYLKPN
NSSATALLKNALELNVTLSLDASHPLIDKSNLMSQASKDKASLNKKRSSLTYDPVNMA
KRLRTQKEIFDQNNKALRKGGHDSKTGSNNADDDFDADMELE"
gene complement(397344..398750)
/gene="MAK11"
/locus_tag="YKL021C"
mRNA complement(397344..398750)
/gene="MAK11"
/locus_tag="YKL021C"
/product="Mak11p"
CDS complement(397344..398750)
/gene="MAK11"
/locus_tag="YKL021C"
/experiment="EXISTENCE:direct assay:GO:0016020 membrane
[PMID:2826479]"
/experiment="EXISTENCE:genetic interaction:GO:0000027
ribosomal large subunit assembly [PMID:17308036]"
/experiment="EXISTENCE:mutant phenotype:GO:0000027
ribosomal large subunit assembly [PMID:17308036]"
/experiment="EXISTENCE:mutant phenotype:GO:0000463
maturation of LSU-rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17308036]"
/experiment="EXISTENCE:mutant phenotype:GO:0000466
maturation of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17308036]"
/experiment="EXISTENCE:mutant phenotype:GO:0042273
ribosomal large subunit biogenesis [PMID:7739558]"
/experiment="EXISTENCE:physical interaction:GO:0000027
ribosomal large subunit assembly [PMID:17308036]"
/note="Protein involved in an early step of 60S ribosomal
subunit biogenesis; essential for cell growth and
replication of killer M1 dsRNA virus; contains four
beta-transducin repeats"
/codon_start=1
/product="Mak11p"
/protein_id="DAA09134.1"
/db_xref="SGD:S000001504"
/translation="MLLNTTYTVFIFFLLRIIKFKIKAENFLEHEKLKTHGTSSRKDP
KGQVKNSCRKMSAIGDKNQFRIIVGSYEHNILCLSLDIPNQKENDAAKTPHFMPIFHF
QAHSLSIKCLAVSRRYLVSGSNDEHIRIYDLQKRKELGTLLSHQGSITALQFSHPASS
SEDAAVSKGSKNSKWLLSASEDHKIMVWRVKDWETVGTLKGHTARVNDVDIHPTNRIA
ISVSDDHSIRLWNLMTLRNAAVLKLRKYNTNGTCVRWLGAKGDYFAVGLRDRVLIYET
GSAKVFKEIVFQRKTLMHIETHILPFDNKEYLSVGISDGNVHFYPCEELFEKVEENEK
QEDDDDKEDISPAFSLLGHTNRIKDFKFYTNEFGTYLVTIGSDGKIVVWDMSTKEQVA
VYDCGERLNCLTLCDESIEKYNTMKKRDAETADIGDQSEVESDTEELKKIMFGEKKKL
NKKKRKQLKKSKVSVELE"
gene complement(398832..402080)
/gene="SPT23"
/locus_tag="YKL020C"
mRNA complement(398832..402080)
/gene="SPT23"
/locus_tag="YKL020C"
/product="Spt23p"
CDS complement(398832..402080)
/gene="SPT23"
/locus_tag="YKL020C"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:11007476]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005789 endoplasmic
reticulum membrane [PMID:11007476]"
/experiment="EXISTENCE:genetic interaction:GO:0030466
silent mating-type cassette heterochromatin formation
[PMID:11063674]"
/experiment="EXISTENCE:genetic interaction:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:9927444]"
/experiment="EXISTENCE:genetic interaction:GO:0070417
cellular response to cold [PMID:11855848]"
/experiment="EXISTENCE:mutant phenotype:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:11557770]"
/note="ER membrane protein involved in regulation of OLE1
transcription; inactive ER form dimerizes and one subunit
is then activated by ubiquitin/proteasome-dependent
processing followed by nuclear targeting; SPT23 has a
paralog, MGA2, that arose from the whole genome
duplication"
/codon_start=1
/product="Spt23p"
/protein_id="DAA09135.1"
/db_xref="SGD:S000001503"
/translation="MMSGTGNVSSMLHSYSANIQHNDGSPDLDLLESELLDIALLNSG
SSLQDPGLLSLNQEKMITAGTTTPGKEDEGELRDDIASLQGLLDRHVQFGRKLPLRTP
YANPLDFININPQSLPLSLEIIGLPKVSRVETQMKLSFRIRNAHARKNFFIHLPSDCI
AKDKFFTSSDDPTNLTIPNRDINERTLFLDAFLLCASNNNSNNFKQTYVCNRCINREK
RRASRRKSGLNDNSIWQNNENKRAIIFNSKQLFIISNNGLSGNSNCINFDLPTRIVCY
CRHHKATNGFVVLFLLRDHNGDILAKTITDPIMIMDKKNASNTTTPTSTSNAQVSPMT
NDTRSFSSPQSDLNFPSEFPLPSNSKNFVISTNCMLDSNCNNNNNDNDNKNNIKTNTA
MMNNNRHFPSPNSSSEDSNHSFSDIHFSNNNDNNLHRSLDSWSSTGFNSSSNPALTTL
TSDFSAASARHTGKRQRSVNEPFMSTPNTFSRLPQKFIDSSKDISNHNSVPVALNNKP
SIQRVIPAQGSINGGIEVTLLGSKFKQGLIIKFGENIALSSQCWNESTMVTYLPPSSK
PGPVLVTIVDPSETSMRNNSNSSVSTSNSTNDILHLNKYTGEKAIFTYVDDTDRQLIE
LALQIVGLKMNGKLEDARNIAKRIVGSDSSPSNNNAGLHSQNSSLNSYTNMMRNINDE
QLITEVIKSFKRNNNLSTVNLSMCDVRGRTLLHLAAFNNWYSLVSLLIKYGSHLNDQD
LFGFTPLHMACINGDLRIIRLLLECNVNIMKKTRNGFIAKQFFLMNYTVNKTRYSNYE
TSLFDDILTRLTKNTTGSSDTQPFERNVSQSSFNSSLFDDDDADHDYVQERKYLLADS
AALAPEQSNCNDNTSFSILDSDSGYDISDCESSSDEIALEFFNTHKIKDFSSKPNEIP
KTTKTSIEPDGSLWNRMLTRLNDELPKYEDLFPKKPKNWELGSKSVEIGPDNSAQMTV
DDSQTSSEDDELEALQVGFNTIFSKKQNFQNDKMLLFFWIPLTLVLLLCFTLSNLGKD
DDMFHNLSKIVQEYLRIGLAKVLLGNERMKTSFKMQLSKFQNNNILNDMRVN"
gene 402568..403518
/gene="RAM2"
/locus_tag="YKL019W"
mRNA 402568..403518
/gene="RAM2"
/locus_tag="YKL019W"
/product="bifunctional protein farnesyltransferase/protein
geranylgeranyltransferase"
CDS 402568..403518
/gene="RAM2"
/locus_tag="YKL019W"
/EC_number="2.5.1.58"
/EC_number="2.5.1.59"
/experiment="EXISTENCE:direct assay:GO:0004660 protein
farnesyltransferase activity [PMID:1763050]"
/experiment="EXISTENCE:direct assay:GO:0004661 protein
geranylgeranyltransferase activity [PMID:2034682]"
/experiment="EXISTENCE:direct assay:GO:0004662
CAAX-protein geranylgeranyltransferase activity
[PMID:1400380]"
/experiment="EXISTENCE:direct assay:GO:0005953
CAAX-protein geranylgeranyltransferase complex
[PMID:1400380]"
/experiment="EXISTENCE:direct assay:GO:0005965 protein
farnesyltransferase complex [PMID:1763050]"
/experiment="EXISTENCE:direct assay:GO:0007323 peptide
pheromone maturation [PMID:1763050]"
/experiment="EXISTENCE:direct assay:GO:0018343 protein
farnesylation [PMID:1763050]"
/experiment="EXISTENCE:direct assay:GO:0018344 protein
geranylgeranylation [PMID:1400380]"
/note="Alpha subunit of farnesyltransferase and
geranylgeranyltransferase-I; farnesyltransferase
(Ram2p-Ram1p heterodimer) catalyzes the addition of
15-carbon isoprenoid farnesyl to substrate proteins
containing a CAAX consensus motif; type I
geranylgeranyltransferase (Ram2p-Cdc43p heterodimer)
catalyzes the addition of the 20-carbon isoprenoid
geranylgeranyl to substrate proteins containing a CaaL
consensus motif; required for membrane localization of Ras
proteins and a-factor"
/codon_start=1
/product="bifunctional protein farnesyltransferase/protein
geranylgeranyltransferase"
/protein_id="DAA09136.1"
/db_xref="SGD:S000001502"
/translation="MEEYDYSDVKPLPIETDLQDELCRIMYTEDYKRLMGLARALISL
NELSPRALQLTAEIIDVAPAFYTIWNYRFNIVRHMMSESEDTVLYLNKELDWLDEVTL
NNPKNYQIWSYRQSLLKLHPSPSFKRELPILKLMIDDDSKNYHVWSYRKWCCLFFSDF
QHELAYASDLIETDIYNNSAWTHRMFYWVNAKDVISKVELADELQFIMDKIQLVPQNI
SPWTYLRGFQELFHDRLQWDSKVVDFATTFIGDVLSLPIGSPEDLPEIESSYALEFLA
YHWGADPCTRDNAVKAYSLLAIKYDPIRKNLWHHKINNLN"
gene complement(403580..403879)
/gene="MCO12"
/locus_tag="YKL018C-A"
mRNA complement(403580..403879)
/gene="MCO12"
/locus_tag="YKL018C-A"
/product="Mco12p"
CDS complement(403580..403879)
/gene="MCO12"
/locus_tag="YKL018C-A"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/note="Putative mitochondrial hypothetical protein;
identified by homology; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm"
/codon_start=1
/product="Mco12p"
/protein_id="DAA09137.1"
/db_xref="SGD:S000007615"
/translation="MLGMIRWVVEGTLVAMLLSAIRRETGMIFFYNQYQLGGWIHRYL
SWGEMCYTRTLKMVKRSKFFRKQLNEDGFGRINDSGPKRRGRDQSQYSSRFVELD"
gene 404102..405091
/gene="SWD2"
/locus_tag="YKL018W"
/gene_synonym="CPS35"
/gene_synonym="SAF37"
mRNA 404102..405091
/gene="SWD2"
/locus_tag="YKL018W"
/gene_synonym="CPS35"
/gene_synonym="SAF37"
/product="WD-repeat containing protein SWD2"
CDS 404102..405091
/gene="SWD2"
/locus_tag="YKL018W"
/gene_synonym="CPS35"
/gene_synonym="SAF37"
/experiment="EXISTENCE:direct assay:GO:0005847 mRNA
cleavage and polyadenylation specificity factor complex
[PMID:12819204]"
/experiment="EXISTENCE:direct assay:GO:0042800 histone
H3K4 methyltransferase activity
[PMID:11742990|PMID:11805083]"
/experiment="EXISTENCE:mutant phenotype:GO:0000723
telomere maintenance [PMID:15146080]"
/experiment="EXISTENCE:mutant phenotype:GO:0031124 mRNA
3'-end processing [PMID:15146080]"
/experiment="EXISTENCE:mutant phenotype:GO:0031126
sno(s)RNA 3'-end processing [PMID:15146080]"
/experiment="EXISTENCE:physical interaction:GO:0048188
Set1C/COMPASS complex
[PMID:11687631|PMID:11742990|PMID:11752412]"
/note="Subunit of the COMPASS (Set1C) histone H3K4
methyltransferase complex; required for Set1C stability
and optimal activity; COMPASS methylates histone H3 on lys
4 and is involved in telomeric silencing; subunit of CPF
(cleavage and polyadenylation factor), a complex involved
in RNAP II transcription termination"
/codon_start=1
/product="WD-repeat containing protein SWD2"
/protein_id="DAA09138.1"
/db_xref="SGD:S000001501"
/translation="MTTVSINKPNLLKFKHVKSFQPQEKDCGPVTSLNFDDNGQFLLT
SSSNDTMQLYSATNCKFLDTIASKKYGCHSAIFTHAQNECIYSSTMKNFDIKYLNLET
NQYLRYFSGHGALVNDLKMNPVNDTFLSSSYDESVRLWDLKISKPQVIIPSLVPNCIA
YDPSGLVFALGNPENFEIGLYNLKKIQEGPFLIIKINDATFSQWNKLEFSNNGKYLLV
GSSIGKHLIFDAFTGQQLFELIGTRAFPMREFLDSGSACFTPDGEFVLGTDYDGRIAI
WNHSDSISNKVLRPQGFIPCVSHETCPRSIAFNPKYSMFVTADETVDFYVYDE"
gene complement(405190..407241)
/gene="HCS1"
/locus_tag="YKL017C"
/gene_synonym="DIP1"
mRNA complement(405190..407241)
/gene="HCS1"
/locus_tag="YKL017C"
/gene_synonym="DIP1"
/product="ATP-dependent 5'-3' DNA helicase HCS1"
CDS complement(405190..407241)
/gene="HCS1"
/locus_tag="YKL017C"
/gene_synonym="DIP1"
/EC_number="3.6.4.12"
/experiment="EXISTENCE:direct assay:GO:0033203 DNA
helicase A complex [PMID:9341218]"
/experiment="EXISTENCE:direct assay:GO:0043139 5'-3' DNA
helicase activity [PMID:9341218|PMID:8257676]"
/experiment="EXISTENCE:direct assay:GO:0043601 nuclear
replisome [PMID:8257676]"
/experiment="EXISTENCE:genetic interaction:GO:0006301
postreplication repair [PMID:20463880]"
/experiment="EXISTENCE:mutant phenotype:GO:0006301
postreplication repair [PMID:20463880]"
/note="Hexameric DNA polymerase alpha-associated DNA
helicase A; involved in lagging strand DNA synthesis;
contains single-stranded DNA stimulated ATPase and dATPase
activities; replication protein A stimulates helicase and
ATPase activities"
/codon_start=1
/product="ATP-dependent 5'-3' DNA helicase HCS1"
/protein_id="DAA09139.1"
/db_xref="SGD:S000001500"
/translation="MNKELASKFLSSIKHEREQDIQTTSRLLTTLSIQQLVQNGLAIN
NIHLENIRSGLIGKLYMELGPNLAVNDKIQRGDIKVGDIVLVRPAKTKVNTKTKPKVK
KVSEDSNGEQAECSGVVYKMSDTQITIALEESQDVIATTFYSYSKLYILKTTNVVTYN
RMESTMRKLSEISSPIQDKIIQYLVNERPFIPNTNSFQNIKSFLNPNLNDSQKTAINF
AINNDLTIIHGPPGTGKTFTLIELIQQLLIKNPEERILICGPSNISVDTILERLTPLV
PNNLLLRIGHPARLLDSNKRHSLDILSKKNTIVKDISQEIDKLIQENKKLKNYKQRKE
NWNEIKLLRKDLKKREFKTIKDLIIQSRIVVTTLHGSSSRELCSLYRDDPNFQLFDTL
IIDEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDKNVIHNLETTLFD
RIIKIFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLIDLPTVDAT
PSEDDDDTKIPLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENLRSFNVPE
NSIGVISPYNAQVSHLKKLIHDELKLTDIEISTVDGFQGREKDVIILSLVRSNEKFEV
GFLKEERRLNVAMTRPRRQLVVVGNIEVLQRCGNKYLKSWSEWCEENADVRYPNIDDY
L"
gene complement(407465..407989)
/gene="ATP7"
/locus_tag="YKL016C"
mRNA complement(407465..407989)
/gene="ATP7"
/locus_tag="YKL016C"
/product="F1F0 ATP synthase subunit d"
CDS complement(407465..407989)
/gene="ATP7"
/locus_tag="YKL016C"
/experiment="EXISTENCE:direct assay:GO:0000274
mitochondrial proton-transporting ATP synthase, stator
stalk [PMID:18937496]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0015986 proton
motive force-driven ATP synthesis [PMID:20691145]"
/experiment="EXISTENCE:direct assay:GO:0046933
proton-transporting ATP synthase activity, rotational
mechanism [PMID:20691145]"
/experiment="EXISTENCE:mutant phenotype:GO:0000274
mitochondrial proton-transporting ATP synthase, stator
stalk [PMID:1832157]"
/experiment="EXISTENCE:mutant phenotype:GO:0015986 proton
motive force-driven ATP synthesis [PMID:1832157]"
/experiment="EXISTENCE:mutant phenotype:GO:0046933
proton-transporting ATP synthase activity, rotational
mechanism [PMID:1832157]"
/note="Subunit d of the stator stalk of mitochondrial F1F0
ATP synthase; F1F0 ATP synthase is a large, evolutionarily
conserved enzyme complex required for ATP synthesis"
/codon_start=1
/product="F1F0 ATP synthase subunit d"
/protein_id="DAA09140.1"
/db_xref="SGD:S000001499"
/translation="MSLAKSAANKLDWAKVISSLRITGSTATQLSSFKKRNDEARRQL
LELQSQPTEVDFSHYRSVLKNTSVIDKIESYVKQYKPVKIDASKQLQVIESFEKHAMT
NAKETESLVSKELKDLQSTLDNIQSARPFDELTVDDLTKIKPEIDAKVEEMVKKGKWD
VPGYKDRFGNLNVM"
gene 408544..411483
/gene="PUT3"
/locus_tag="YKL015W"
mRNA 408544..411483
/gene="PUT3"
/locus_tag="YKL015W"
/product="Put3p"
CDS 408544..411483
/gene="PUT3"
/locus_tag="YKL015W"
/experiment="EXISTENCE:direct assay:GO:0000978 RNA
polymerase II cis-regulatory region sequence-specific DNA
binding [PMID:1986247|PMID:8846888]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0043565
sequence-specific DNA binding
[PMID:19111667|PMID:19158363]"
/experiment="EXISTENCE:mutant phenotype:GO:0000972
transcription-dependent tethering of RNA polymerase II
gene DNA at nuclear periphery [PMID:22579222]"
/experiment="EXISTENCE:mutant phenotype:GO:0001228
DNA-binding transcription activator activity, RNA
polymerase II-specific [PMID:8846888]"
/experiment="EXISTENCE:mutant phenotype:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:2689862|PMID:8846888]"
/experiment="EXISTENCE:mutant phenotype:GO:2001158
positive regulation of proline catabolic process to
glutamate [PMID:2689862]"
/note="Transcriptional activator; binds specific gene
recruitment sequences and is required for DNA zip
code-mediated targeting of genes to nuclear periphery;
regulates proline utilization genes, constitutively binds
PUT1 and PUT2 promoters as a dimer, undergoes
conformational change to form active state; binds other
promoters only under activating conditions; differentially
phosphorylated in presence of different nitrogen sources;
has a Zn(2)-Cys(6) binuclear cluster domain"
/codon_start=1
/product="Put3p"
/protein_id="DAA09141.1"
/db_xref="SGD:S000001498"
/translation="MVTDQGSRHSIQSKQPAYVNKQPQKRQQRSSVACLSCRKRHIKC
PGGNPCQKCVTSNAICEYLEPSKKIVVSTKYLQQLQKDLNDKTEENNRLKALLLERPV
SVRGKDNSDDDERHINNAPSSDTLEVSSAPAAPIFDLMSNSNTASDNDNDDDNSNRIT
NNRSYDHSLEKYYKKAISIFKQPANANGENGNGANGHEDDDEDDEEISTNFAQRSGRL
IESHNGFHYFVGSSSMTLFGLEIQSLVTKYISVKNFRPLPINTKNKILNSNLNPAISS
FINSNNYLFSSYNFLNPISTIVNLNSINDNLSPLMFKIILKSDTDGSSGQEEVIQFQL
PSYNYTKLLIDCFINYNDGCFYFFNEGLVKCGINKLYLENKWLYYDNTKKALDNENDP
ILQAVWFCKILLILAVGEMYLGSINNEMLKNYSNQPKLPGSKFFQMGSKIFNCLFSSE
RLENVTKKGGIEVLLLYAFFLQVADYTLASYFYFGQALRTCLILGLHVDSQSDTLSRY
EIEHHRRLWWTVYMFERMLSSKAGLPLSFTDYTISTALPADIDDETIEEKNSHYVFRK
AELISNCVTIVKINAQILSKLYQRQPETNIIITLKVVIKQLLEWRNNLSDSLQVDFTQ
KDEDFKISRLSTNMFTEYFQGINLAVRPLLFHFASIQLKRFKTSNTFVNLQNYSATIS
SLLTCSLHASVNTIRSLWSLLQNSMLAMFSYMDREYLFTSSCTLLLFNTAFGIHEQTL
YHLDHSLEIFTQMRNLGNIPAGLRRAQLLTLMANLDFHGIMNDLITKYNDILKFDSMN
CENDNIVEDSNEPKRETEKCKPHKDGDRIDPSIIDCDKSNTNTNMIKNESISNIVSIL
PEGAKPTLTDYSNGNNDVNDINVNNSEPSTFFDIITASLENSYQTTLTEKGSQVMEKN
MDQLDSVHNLNDDDLQQLLEDLGNIDHSDEKLWKEITDQAMWLGNTMDPTAAAGSEID
FTDYLGP"
gene complement(411619..416913)
/gene="URB1"
/locus_tag="YKL014C"
/gene_synonym="NPA1"
mRNA complement(411619..416913)
/gene="URB1"
/locus_tag="YKL014C"
/gene_synonym="NPA1"
/product="Urb1p"
CDS complement(411619..416913)
/gene="URB1"
/locus_tag="YKL014C"
/gene_synonym="NPA1"
/experiment="EXISTENCE:direct assay:GO:0003729 mRNA
binding [PMID:23222640]"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:14562095|PMID:15208443|PMID:22842922]"
/experiment="EXISTENCE:mutant phenotype:GO:0000463
maturation of LSU-rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15208443]"
/experiment="EXISTENCE:mutant phenotype:GO:0000466
maturation of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15208443]"
/note="Protein required for the normal accumulation of 25S
and 5.8S rRNAs; nucleolar protein; associated with the
27SA2 pre-ribosomal particle; proposed to be involved in
the biogenesis of the 60S ribosomal subunit"
/codon_start=1
/product="Urb1p"
/protein_id="DAA09142.1"
/db_xref="SGD:S000001497"
/translation="MSNHSEAYGSRDQRREKYTQGKEFEDGTLETLESIISAVEDETL
SKDYQPLIVFFQRGFGAQLVQTWSYYAQVNNHGKFSKTTSLLTKTLRVLSSDTSTVTI
GSGLIRLILTDYTKVLYRGLNNMRAQLTNPILRLLKQIVNFNNGQHIEELVSYFDFSL
PILPRLLVPSKSELANGNSSADSSKHDSLRFTFIKFWLTLISNASPFVRKELLTENFK
IMSNLFKFMNKADSDKLSEHILSVFINDILKEKSFKRTTKTKILNELAASKIHHFYYS
SNKNLVKKANEFFLTFGASRDFSVAFPDNCVWFKNSVADGASHGAPITVNQVEFQIHN
KLLFNTLRLFKPWEDTLQLGTLIKILENVPELVAPYSIFLTTNGNYDPKMTSYWFGIT
LLINKIINLKIPQFMEKVDSNIPPATSLVIENILPSLLTKSSLVKSLQFETPIIRQLA
CQSIVLALKKLEKVSTFYDQKGWRNEKTILLNEFHTRIPDLPIFVSTLSNSLASNKDN
RILPLSISIIFNYYSKMFPNLFSINLPSSNIYTDIMQKSKISGIEFAILDNYLQFQEF
NSTQTRWWNPSSGGNSLFTLLLKLASSKNASNVITTRISNLLDELTRTNVIFNISLIS
PVMALVNSLQGLSLQVSEIDNMEQVWKWFDETISRVVKTPYKYVDMAKEYNYISPFIM
CLSEQWKYVDKSGNPEFLIKWLILFLRNMIFIGEDHIGIDKLVKNVFPEVSDHDVNIY
LKLDSFEENIKKTNSSNSLISSMKSSSFFQYISALPSKNLMNISRLPVNKLDAAGILF
RVQLLVEDDSVVYDNWFEATACELTGKIASYMVTDTEFPIIKVLERYINFALPKLAIE
KRNALLMKKSRFMCNLIGAVCFETGHQLVEFREIIQKVVFSGENVEEYANYNELYQKE
DVNAFLTSVSEYLSTSALTSLLMCSTKLESTRNILQKLFNEGKTIKISLVKNILNKAA
NEDPASIKEVNISLAKFFEENKVCVDASSDPMGKLSLSETTSLINSFVSSDLNYLVLK
AFYRWEHFSFPSFIPSIWRIKDSPLLSIVTTAALFKHMQDKDFSAFAHETISKYGNEI
AKSTYTTSKSEIFDEILNMITTYIDFYDETKRNEILKCVLSQSDHKYHAATVRYIAAH
NNFTYPGVETWLHKTLLYLTKYLSERKVISNSFFELLRAMAELLKLEEVPNKLNVKII
NSQLEAILGSEWIKQIKVLEYVIVLIFCVSKKSIQSQRMVQLLLSNDSYSSIMIKDND
EDSSYRKFLSTMILFSLFSIDPVVNSTPIVQEKLLTFYSGTISSNDKLILKILETIES
HTATSWTNMIFSWEFIKDEEEEILEAIGDTRLITKEREGLILTLQKNMIKKSIDRYVL
ERPQVPELYTDSNTNNYDATTRCDLVKKYYDDTERSGVDMYDPLFLLLLIIHNKELVK
MVKDDEGNVTYRYEFENFLDCKIFQFIICSLSDCHTVANISYEHLSNLASSLEKKTAQ
MNLEKQITSKDNERKESDSDLIKYNSIYQVLIKRILYQRQQNQDPINPLIWFSISRIV
DLLGSPTAPLHEKAYRWVLSNSTIRSWDIPMVSDVMMSYNKRQQDDNKKEIDMEIYYG
ELSWVLTTICKGIKTDEDYKMLEKKGVFEWLLNLINMPYLKERLRELIYFIFYKVQRV
ADDGGLNLISRNGIVSFFEVLNNNIKSRLPQDDILNNIGTLRNENRGTLNTTLRLAQE
QNGIEKLLLGYNELVKSQKRLILWTEGDSDNVVKRLRK"
rep_origin 417185..417417
/note="ARS1113; Autonomously Replicating Sequence"
/db_xref="SGD:S000118405"
gene complement(417508..418023)
/gene="ARC19"
/locus_tag="YKL013C"
mRNA complement(417508..418023)
/gene="ARC19"
/locus_tag="YKL013C"
/product="Arc19p"
CDS complement(417508..418023)
/gene="ARC19"
/locus_tag="YKL013C"
/experiment="EXISTENCE:direct assay:GO:0005885 Arp2/3
protein complex [PMID:10377407|PMID:9210376]"
/experiment="EXISTENCE:mutant phenotype:GO:0044396 actin
cortical patch organization [PMID:10377407]"
/experiment="EXISTENCE:mutant phenotype:GO:0060090
molecular adaptor activity [PMID:10377407]"
/note="Subunit of the ARP2/3 complex; ARP2/3 is required
for the motility and integrity of cortical actin patches;
mutation is functionally complemented by human ARPC4"
/codon_start=1
/product="Arc19p"
/protein_id="DAA09143.1"
/db_xref="SGD:S000001496"
/translation="MSQSLRPYLTAVRYSLEAALTLSNFSSQEVERHNRPEVEVPNTS
AELLLQPMHISRNENEQVLIEPSVNSVRMSLMVKQADEIEQILVHKFTRFLEQRAEAF
YILRRVPIPGYSISFLITNKHTESMKTGKLVDFIIEFMEDVDKEISEIKLFLNARARF
VAEAYLDEFVY"
gene 418310..420061
/gene="PRP40"
/locus_tag="YKL012W"
mRNA 418310..420061
/gene="PRP40"
/locus_tag="YKL012W"
/product="Prp40p"
CDS 418310..420061
/gene="PRP40"
/locus_tag="YKL012W"
/experiment="EXISTENCE:direct assay:GO:0000398 mRNA
splicing, via spliceosome [PMID:8622699]"
/experiment="EXISTENCE:direct assay:GO:0003723 RNA binding
[PMID:8622699]"
/experiment="EXISTENCE:direct assay:GO:0005685 U1 snRNP
[PMID:9630245]"
/experiment="EXISTENCE:direct assay:GO:0071004 U2-type
prespliceosome [PMID:16618970]"
/experiment="EXISTENCE:mutant phenotype:GO:0005634 nucleus
[PMID:15020406]"
/note="U1 snRNP protein involved in splicing; interacts
with the branchpoint-binding protein during the formation
of the second commitment complex"
/codon_start=1
/product="Prp40p"
/protein_id="DAA09144.1"
/db_xref="SGD:S000001495"
/translation="MSIWKEAKDASGRIYYYNTLTKKSTWEKPKELISQEELLLRENG
WKAAKTADGKVYYYNPTTRETSWTIPAFEKKVEPIAEQKHDTVSHAQVNGNRIALTAG
EKQEPGRTINEEESQYANNSKLLNVRRRTKEEAEKEFITMLKENQVDSTWSFSRIISE
LGTRDPRYWMVDDDPLWKKEMFEKYLSNRSADQLLKEHNETSKFKEAFQKMLQNNSHI
KYYTRWPTAKRLIADEPIYKHSVVNEKTKRQTFQDYIDTLIDTQKESKKKLKTQALKE
LREYLNGIITTSSSETFITWQQLLNHYVFDKSKRYMANRHFKVLTHEDVLNEYLKIVN
TIENDLQNKLNELRLRNYTRDRIARDNFKSLLREVPIKIKANTRWSDIYPHIKSDPRF
LHMLGRNGSSCLDLFLDFVDEQRMYIFAQRSIAQQTLIDQNFEWNDADSDEITKQNIE
KVLENDRKFDKVDKEDISLIVDGLIKQRNEKIQQKLQNERRILEQKKHYFWLLLQRTY
TKTGKPKPSTWDLASKELGESLEYKALGDEDNIRRQIFEDFKPESSAPTAESATANLT
LTASKKRHLTPAVELDY"
gene complement(420155..421216)
/gene="CCE1"
/locus_tag="YKL011C"
/gene_synonym="MGT1"
mRNA complement(420155..421216)
/gene="CCE1"
/locus_tag="YKL011C"
/gene_synonym="MGT1"
/product="cruciform cutting endonuclease"
CDS complement(420155..421216)
/gene="CCE1"
/locus_tag="YKL011C"
/gene_synonym="MGT1"
/EC_number="3.1.21.10"
/experiment="EXISTENCE:direct assay:GO:0004520 DNA
endonuclease activity [PMID:8413191]"
/experiment="EXISTENCE:direct assay:GO:0005743
mitochondrial inner membrane [PMID:8413191]"
/experiment="EXISTENCE:genetic interaction:GO:0000002
mitochondrial genome maintenance [PMID:12198175]"
/note="Mitochondrial cruciform cutting endonuclease;
cleaves Holliday junctions formed during recombination of
mitochondrial DNA; CCE1 has a paralog, MRS1, that arose
from the whole genome duplication"
/codon_start=1
/product="cruciform cutting endonuclease"
/protein_id="DAA09145.1"
/db_xref="SGD:S000001494"
/translation="MSTAQKAKILQLIDSCCQNAKSTQLKSLSFVIGAVNGTTKEAKR
TYIQEQCEFLEKLRQQKIREGRINILSMDAGVSNFAFSKMQLLNNDPLPKVLDWQKIN
LEEKFFQNLKKLSLNPAETSELVFNLTEYLFESMPIPDMFTIERQRTRTMSSRHILDP
ILKVNILEQILFSNLENKMKYTNKIPNTSKLRYMVCSSDPHRMTSYWCIPREETPTSS
KKLKSNKHSKDSRIKLVKKILSTSILEGNSTSSTKLVEFIGVWNNRIRNALTKKKSFK
LCDILEIQDNSGVRKDDDLADSFLHCLSWMEWLKNYESITELLNSKTLVKTQFGQVFE
FCENKVQKLKFLQNTYNND"
gene complement(421424..425875)
/gene="UFD4"
/locus_tag="YKL010C"
mRNA complement(421424..425875)
/gene="UFD4"
/locus_tag="YKL010C"
/product="putative ubiquitin-protein ligase UFD4"
CDS complement(421424..425875)
/gene="UFD4"
/locus_tag="YKL010C"
/EC_number="2.3.2.26"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0035519 protein
K29-linked ubiquitination [PMID:28165462]"
/experiment="EXISTENCE:direct assay:GO:0061630 ubiquitin
protein ligase activity [PMID:10089879]"
/experiment="EXISTENCE:mutant phenotype:GO:0006511
ubiquitin-dependent protein catabolic process
[PMID:10089879]"
/experiment="EXISTENCE:mutant phenotype:GO:0010994 free
ubiquitin chain polymerization [PMID:22497224]"
/experiment="EXISTENCE:physical interaction:GO:1904855
proteasome regulatory particle binding
[PMID:10688918|PMID:12447385]"
/note="Ubiquitin-protein ligase (E3); interacts with Rpt4p
and Rpt6p, two subunits of the 19S particle of the 26S
proteasome; involved in K29-linked ubiquitin-dependent
protein catabolism, including ubiquitin fusion proteins;
relative distribution to the nucleus increases upon DNA
replication stress"
/codon_start=1
/product="putative ubiquitin-protein ligase UFD4"
/protein_id="DAA09146.1"
/db_xref="SGD:S000001493"
/translation="MSENNSHNLDEHESHSENSDYMMDTQVEDDYDEDGHVQGEYSYY
PDEDEDEHMLSSVGSFEADDGEDDDNDYHHEDDSGLLYGYHRTQNGSDEDRNEEEDGL
ERSHDNNEFGSNPLHLPDILETFAQRLEQRRQTSEGLGQHPVGRTLPEILSMIGGRME
RSAESSARNERISKLIENTGNASEDPYIAMESLKELSENILMMNQMVVDRIIPMETLI
GNIAAILSDKILREELELQMQACRCMYNLFEVCPESISIAVDEHVIPILQGKLVEISY
IDLAEQVLETVEYISRVHGRDILKTGQLSIYVQFFDFLTIHAQRKAIAIVSNACSSIR
TDDFKTIVEVLPTLKPIFSNATDQPILTRLVNAMYGICGALHGVDKFETLFSLDLIER
IVQLVSIQDTPLENKLKCLDILTVLAMSSDVLSRELREKTDIVDMATRSFQHYSKSPN
AGLHETLIYVPNSLLISISRFIVVLFPPEDERILSADKYTGNSDRGVISNQEKFDSLV
QCLIPILVEIYTNAADFDVRRYVLIALLRVVSCINNSTAKAINDQLIKLIGSILAQKE
TASNANGTYSSEAGTLLVGGLSLLDLICKKFSELFFPSIKREGIFDLVKDLSVDFNNI
DLKEDGNENISLSDEEGDLHSSIEECDEGDEEYDYEFTDMEIPDSVKPKKISIHIFRT
LSLAYIKNKGVNLVNRVLSQMNVEQEAITEELHQIEGVVSILENPSTPDKTEEDWKGI
WSVLKKCIFHEDFDVSGFEFTSTGLASSITKRITSSTVSHFILAKSFLEVFEDCIDRF
LEILQSALTRLENFSIVDCGLHDGGGVSSLAKEIKIKLVYDGDASKDNIGTDLSSTIV
SVHCIASFTSLNEFLRHRMVRMRFLNSLIPNLTSSSTEADREEEENCLDHMRKKNFDF
FYDNEKVDMESTVFGVIFNTFVRRNRDLKTLWDDTHTIKFCKSLEGNNRESEAAEEAN
EGKKLRDFYKKREFAQVDTGSSADILTLLDFLHSCGVKSDSFINSKLSAKLARQLDEP
LVVASGALPDWSLFLTRRFPFLFPFDTRMLFLQCTSFGYGRLIQLWKNKSKGSKDLRN
DEALQQLGRITRRKLRISRKTIFATGLKILSKYGSSPDVLEIEYQEEAGTGLGPTLEF
YSVVSKYFARKSLNMWRCNSYSYRSEMDVDTTDDYITTLLFPEPLNPFSNNEKVIELF
GYLGTFVARSLLDNRILDFRFSKVFFELLHRMSTPNVTTVPSDVETCLLMIELVDPLL
AKSLKYIVANKDDNMTLESLSLTFTVPGNDDIELIPGGCNKSLNSSNVEEYIHGVIDQ
ILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVDIFGRVEEDWSMATLYTNLNAEH
GYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLNPKFTVVLKHAED
GLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAGAFLLS"
gene 426242..426952
/gene="MRT4"
/locus_tag="YKL009W"
mRNA 426242..426952
/gene="MRT4"
/locus_tag="YKL009W"
/product="Mrt4p"
CDS 426242..426952
/gene="MRT4"
/locus_tag="YKL009W"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005654 nucleoplasm
[PMID:19797079]"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:14562095|PMID:19797078|PMID:19797079]"
/experiment="EXISTENCE:direct assay:GO:0030687
preribosome, large subunit precursor
[PMID:11583614|PMID:17443350|PMID:23212245]"
/experiment="EXISTENCE:genetic interaction:GO:0000055
ribosomal large subunit export from nucleus
[PMID:19797079]"
/experiment="EXISTENCE:mutant phenotype:GO:0000055
ribosomal large subunit export from nucleus
[PMID:19797079]"
/experiment="EXISTENCE:mutant phenotype:GO:0000956
nuclear-transcribed mRNA catabolic process
[PMID:10471698]"
/experiment="EXISTENCE:mutant phenotype:GO:0006364 rRNA
processing [PMID:12837249]"
/experiment="EXISTENCE:mutant phenotype:GO:0042273
ribosomal large subunit biogenesis [PMID:11583614]"
/note="Protein involved in mRNA turnover and ribosome
assembly; required at post-transcriptional step for
efficient retrotransposition; localizes to the nucleolus"
/codon_start=1
/product="Mrt4p"
/protein_id="DAA09147.1"
/db_xref="SGD:S000001492"
/translation="MPRSKRSKLVTLAQTDKKGRENKERIFDEVREALDTYRYVWVLH
LDDVRTPVLQEIRTSWAGSKLIMGKRKVLQKALGEKREEEYKENLYQLSKLCSGVTGL
LFTDEDVNTVKEYFKSYVRSDYSRPNTKAPLTFTIPEGIVYSRGGQIPAEEDVPMIHS
LEPTMRNKFEIPTKIKAGKITIDSPYLVCTEGEKLDVRQALILKQFGIAASEFKVKVS
AYYDNDSSTVESTNINME"
gene complement(427295..428551)
/gene="LAC1"
/locus_tag="YKL008C"
/gene_synonym="DGT1"
mRNA complement(427295..428551)
/gene="LAC1"
/locus_tag="YKL008C"
/gene_synonym="DGT1"
/product="sphingosine N-acyltransferase LAC1"
CDS complement(427295..428551)
/gene="LAC1"
/locus_tag="YKL008C"
/gene_synonym="DGT1"
/EC_number="2.3.1.297"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:10198056]"
/experiment="EXISTENCE:direct assay:GO:0034399 nuclear
periphery [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0046513 ceramide
biosynthetic process [PMID:15692566]"
/experiment="EXISTENCE:direct assay:GO:0050291 sphingosine
N-acyltransferase activity [PMID:15692566]"
/experiment="EXISTENCE:direct assay:GO:0061576 acyl-CoA
ceramide synthase complex [PMID:15692566]"
/experiment="EXISTENCE:mutant phenotype:GO:0046513
ceramide biosynthetic process [PMID:11694577]"
/experiment="EXISTENCE:mutant phenotype:GO:0050291
sphingosine N-acyltransferase activity
[PMID:11387200|PMID:11694577]"
/note="Ceramide synthase component; involved in synthesis
of ceramide from C26(acyl)-coenzyme A and
dihydrosphingosine or phytosphingosine, functionally
equivalent to Lag1p; LAC1 has a paralog, LAG1, that arose
from the whole genome duplication"
/codon_start=1
/product="sphingosine N-acyltransferase LAC1"
/protein_id="DAA09148.1"
/db_xref="SGD:S000001491"
/translation="MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETK
ESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSG
NTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAI
RLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPF
LFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGL
PIYITMDVSDFLLSFSKTLNYLDSGLAFFSFAIFVVAWIYLRHYINLKILWSVLTQFR
TEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRGILKDDR
SDSESDEESDESSTTPTDSTPTKKDI"
gene 429302..430108
/gene="CAP1"
/locus_tag="YKL007W"
mRNA 429302..430108
/gene="CAP1"
/locus_tag="YKL007W"
/product="Cap1p"
CDS 429302..430108
/gene="CAP1"
/locus_tag="YKL007W"
/experiment="EXISTENCE:direct assay:GO:0000131 incipient
cellular bud site [PMID:1315784]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005934 cellular
bud tip [PMID:1315784|PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005935 cellular
bud neck [PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0008290 F-actin
capping protein complex [PMID:14769858]"
/experiment="EXISTENCE:direct assay:GO:0030479 actin
cortical patch [PMID:38088874|PMID:14769858]"
/experiment="EXISTENCE:direct assay:GO:0043332 mating
projection tip [PMID:19053807]"
/experiment="EXISTENCE:direct assay:GO:0051016 barbed-end
actin filament capping [PMID:14769858|PMID:1315784]"
/experiment="EXISTENCE:direct assay:GO:0110085 mitotic
actomyosin contractile ring [PMID:38088874]"
/experiment="EXISTENCE:mutant phenotype:GO:0008290 F-actin
capping protein complex [PMID:14769858]"
/experiment="EXISTENCE:mutant phenotype:GO:0051015 actin
filament binding [PMID:14769858]"
/note="Alpha subunit of the capping protein heterodimer
(Cap1p and Cap2p); capping protein (CP) binds to the
barbed ends of actin filaments preventing further
polymerization; localized predominantly to cortical actin
patches; protein increases in abundance and relocalizes
from bud neck to plasma membrane upon DNA replication
stress"
/codon_start=1
/product="Cap1p"
/protein_id="DAA09149.1"
/db_xref="SGD:S000001490"
/translation="MSSSKFEEVINKIINDSPPGELREVYDDLIKITSENSKNTILDA
IENYNVQNCIPIEVNGNSVIISKYNKEGAKFFDPVNSVIFSVNHLERKGLDIEPYEFT
HAKIEKGQLKELHDKLHEYLLQSFPGDVSFAVYPVPEEISKISIIIVSTKYNPNNFWN
GHWRSSYIYDLETRELSGQISTQVHYYEDGNVSFQSGKDINQSNVDDVVCTIRDIETN
FENDLDLSFFDLNEKQFKALRRRLPVTRSKINWGSAIGSYRLGKNAAEGK"
gene complement(430198..430632)
/gene="SFT1"
/locus_tag="YKL006C-A"
mRNA complement(join(430198..430455,430597..430632))
/gene="SFT1"
/locus_tag="YKL006C-A"
/product="Sft1p"
CDS complement(join(430198..430455,430597..430632))
/gene="SFT1"
/locus_tag="YKL006C-A"
/experiment="EXISTENCE:direct assay:GO:0000138 Golgi trans
cisterna [PMID:7596416]"
/experiment="EXISTENCE:direct assay:GO:0005484 SNAP
receptor activity [PMID:11959998]"
/experiment="EXISTENCE:direct assay:GO:0006906 vesicle
fusion [PMID:11959998]"
/experiment="EXISTENCE:direct assay:GO:0031201 SNARE
complex [PMID:11959998]"
/experiment="EXISTENCE:mutant phenotype:GO:0006891
intra-Golgi vesicle-mediated transport
[PMID:10591633|PMID:7596416]"
/note="Intra-Golgi v-SNARE; required for transport of
proteins between an early and a later Golgi compartment"
/codon_start=1
/product="Sft1p"
/protein_id="DAA09150.1"
/db_xref="SGD:S000002101"
/translation="MSNSRYSQTESNNDRKLEGLANKLATFRNINQEIGDRAVSDSSV
INQMTDSLGSMFTDIKNSSSRLTRSLKAGNSIWRMVGLALLIFFILYTLFKLF"
gene complement(431030..431138)
/gene="SNR87"
/locus_tag="YNCK0015C"
ncRNA complement(431030..431138)
/ncRNA_class="snoRNA"
/gene="SNR87"
/locus_tag="YNCK0015C"
/product="SNR87"
/experiment="EXISTENCE:curator inference:GO:0005730
nucleolus [PMID:16484372]"
/experiment="EXISTENCE:curator inference:GO:0031428 box
C/D RNP complex [PMID:16484372]"
/experiment="EXISTENCE:mutant phenotype:GO:0030562 rRNA
2'-O-ribose methylation guide activity [PMID:16484372]"
/experiment="EXISTENCE:mutant phenotype:GO:0031167 rRNA
methylation [PMID:16484372]"
/note="C/D box small nucleolar RNA (snoRNA); guides
2'-O-methylation of small subunit (SSU) rRNA at position
A436"
/db_xref="SGD:S000114301"
gene 431906..432720
/gene="RPL14A"
/locus_tag="YKL006W"
mRNA join(431906..432034,432433..432720)
/gene="RPL14A"
/locus_tag="YKL006W"
/product="ribosomal 60S subunit protein L14A"
CDS join(431906..432034,432433..432720)
/gene="RPL14A"
/locus_tag="YKL006W"
/experiment="EXISTENCE:curator inference:GO:0002181
cytoplasmic translation [PMID:11983894]"
/experiment="EXISTENCE:curator inference:GO:0003735
structural constituent of ribosome [PMID:11983894]"
/experiment="EXISTENCE:direct assay:GO:0003723 RNA binding
[PMID:6337137]"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:29788267]"
/experiment="EXISTENCE:direct assay:GO:0022625 cytosolic
large ribosomal subunit [PMID:11983894]"
/experiment="EXISTENCE:mutant phenotype:GO:0000027
ribosomal large subunit assembly [PMID:29788267]"
/experiment="EXISTENCE:mutant phenotype:GO:0000470
maturation of LSU-rRNA [PMID:29788267]"
/experiment="EXISTENCE:mutant phenotype:GO:0016236
macroautophagy [PMID:19793921]"
/note="Ribosomal 60S subunit protein L14A; N-terminally
acetylated; homologous to mammalian ribosomal protein L14,
no bacterial homolog; RPL14A has a paralog, RPL14B, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 60S subunit protein L14A"
/protein_id="DAA09151.1"
/db_xref="SGD:S000001489"
/translation="MSTDSIVKASNWRLVEVGRVVLIKKGQSAGKLAAIVEIIDQKKV
LIDGPKAGVPRQAINLGQVVLTPLTFALPRGARTATVSKKWAAAAVCEKWAASSWAKK
IAQRERRAALTDFERFQVMVLRKQKRYTVKKALAKA"
gene complement(433093..434877)
/gene="BYE1"
/locus_tag="YKL005C"
mRNA complement(433093..434877)
/gene="BYE1"
/locus_tag="YKL005C"
/product="Bye1p"
CDS complement(433093..434877)
/gene="BYE1"
/locus_tag="YKL005C"
/experiment="EXISTENCE:curator inference:GO:0005634
nucleus [PMID:14704159]"
/experiment="EXISTENCE:direct assay:GO:0003682 chromatin
binding [PMID:24003114]"
/experiment="EXISTENCE:direct assay:GO:0035064 methylated
histone binding [PMID:17142463]"
/experiment="EXISTENCE:genetic interaction:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:14704159]"
/experiment="EXISTENCE:mutant phenotype:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:14704159]"
/note="Negative regulator of transcription elongation;
contains a TFIIS-like domain that associates with
chromatin and a PHD domain that interacts with H3K4me3;
multicopy suppressor of temperature-sensitive ess1
mutations, binds RNA polymerase II large subunit"
/codon_start=1
/product="Bye1p"
/protein_id="DAA09152.1"
/db_xref="SGD:S000001488"
/translation="MSVRTSSRSNKGQNKYIEYLLQEETEAPKKKRTKKKVDSAIEKN
KKSDSSQEPRKDTENVRTDEVDEADEGYVRCLCGANNENYDAAEYSHGDMVQCDGCDT
WQHIKCMTDGKDTIDGLMSEDSKYYCELCDPSLYAHLETSKEAEVSEDEDYHDDVYKP
VNDHDDNDADVFLDEESPRKRKRSPDSAKGIHIKSKQVKKSNGSKKRNKSIDAAKSDT
AENEMPTRKDFESEKEHKLRYNAEKMFSTLFSKFIVPETIEAKLYELPDGKDVISISQ
EFAHNLEEELYKACLNVEFGTLDKIYTEKVRSLYSNLKDKKNLELKAHVVEGKLPLNK
LVNMNASELANPDLQEFKEKRDKIILENFIVEVPDKPMYVKTHKGDELIEDIAEPQED
ILYSKDSIRLHNIDSIDSDKSKIEQTHAISKEPSPSTIINEESLNCAFLYPGLGLEFT
GYLNYIGASQKLRRDIFKEAIGDGKLYVEGRLPTTTAAPYLKEISCSRAILVYQLFPS
NDSESKTTFADVVDSLENKGRIAGIKPKTRYEKDFYIVPSKGGEIPEILKDILGSHND
ERSERFSRMKSDERTLFAFVVVKQEFIH"
gene 435580..436785
/gene="AUR1"
/locus_tag="YKL004W"
mRNA 435580..436785
/gene="AUR1"
/locus_tag="YKL004W"
/product="inositol phosphorylceramide synthase"
CDS 435580..436785
/gene="AUR1"
/locus_tag="YKL004W"
/EC_number="2.7.1.227"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:10888667]"
/experiment="EXISTENCE:direct assay:GO:0006673 inositol
phosphoceramide metabolic process [PMID:19726565]"
/experiment="EXISTENCE:direct assay:GO:0045140 inositol
phosphoceramide synthase activity [PMID:19047657]"
/experiment="EXISTENCE:mutant phenotype:GO:0030148
sphingolipid biosynthetic process [PMID:9092515]"
/experiment="EXISTENCE:mutant phenotype:GO:0045140
inositol phosphoceramide synthase activity [PMID:9092515]"
/experiment="EXISTENCE:physical interaction:GO:0070916
inositol phosphoceramide synthase complex [PMID:19726565]"
/note="Phosphatidylinositol:ceramide phosphoinositol
transferase; required for sphingolipid synthesis; can
mutate to confer aureobasidin A resistance; also known as
IPC synthase"
/codon_start=1
/product="inositol phosphorylceramide synthase"
/protein_id="DAA09153.1"
/db_xref="SGD:S000001487"
/translation="MANPFSRWFLSERPPNCHVADLETSLDPHQTLLKVQKYKPALSD
WVHYIFLGSIMLFVFITNPAPWIFKILFYCFLGTLFIIPATSQFFFNALPILTWVALY
FTSSYFPDDRRPPITVKVLPAVETILYGDNLSDILATSTNSFLDILAWLPYGLFHFGA
PFVVAAILFVFGPPTVLQGYAFAFGYMNLFGVIMQNVFPAAPPWYKILYGLQSANYDM
HGSPGGLARIDKLLGINMYTTAFSNSSVIFGAFPSLHSGCATMEALFFCYCFPKLKPL
FIAYVCWLWWSTMYLTHHYFVDLMAGSVLSYVIFQYTKYTHLPIVDTSLFCRWSYTSI
EKYDISKSDPLAADSNDIESVPLSNLELDFDLNMTDEPSVSPSLFDGSTSVSRSSATS
ITSLGVKRA"
gene complement(437097..437492)
/gene="MRP17"
/locus_tag="YKL003C"
/gene_synonym="bS6m"
mRNA complement(437097..437492)
/gene="MRP17"
/locus_tag="YKL003C"
/gene_synonym="bS6m"
/product="mitochondrial 37S ribosomal protein YmS16"
CDS complement(437097..437492)
/gene="MRP17"
/locus_tag="YKL003C"
/gene_synonym="bS6m"
/experiment="EXISTENCE:curator inference:GO:0032543
mitochondrial translation [PMID:12392552|PMID:9151978]"
/experiment="EXISTENCE:direct assay:GO:0003735 structural
constituent of ribosome [PMID:12392552|PMID:9151978]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005763
mitochondrial small ribosomal subunit
[PMID:12392552|PMID:9151978]"
/note="Mitochondrial ribosomal protein of the small
subunit; MRP17 exhibits genetic interactions with PET122,
encoding a COX3-specific translational activator"
/codon_start=1
/product="mitochondrial 37S ribosomal protein YmS16"
/protein_id="DAA09154.1"
/db_xref="SGD:S000001486"
/translation="MLYELIGLVRITNSNAPKLEAKELSSTIGKLIIQNRGVVRDIVP
MGIRYLPKIMKKDQEKHFRAYHFLMLFDSSAAVQSEILRTLKKDPRVIRSSIVKVDLD
KQLDRASSLHRSLGKKSILELVNEDYQSI"
gene 437778..438544
/gene="DID4"
/locus_tag="YKL002W"
/gene_synonym="CHM2"
/gene_synonym="GRD7"
/gene_synonym="REN1"
/gene_synonym="VPL2"
/gene_synonym="VPS14"
/gene_synonym="VPS2"
/gene_synonym="VPT14"
mRNA join(437778..437837,437906..438544)
/gene="DID4"
/locus_tag="YKL002W"
/gene_synonym="CHM2"
/gene_synonym="GRD7"
/gene_synonym="REN1"
/gene_synonym="VPL2"
/gene_synonym="VPS14"
/gene_synonym="VPS2"
/gene_synonym="VPT14"
/product="ESCRT-III subunit protein DID4"
CDS join(437778..437837,437906..438544)
/gene="DID4"
/locus_tag="YKL002W"
/gene_synonym="CHM2"
/gene_synonym="GRD7"
/gene_synonym="REN1"
/gene_synonym="VPL2"
/gene_synonym="VPS14"
/gene_synonym="VPS2"
/gene_synonym="VPT14"
/experiment="EXISTENCE:direct assay:GO:0000815 ESCRT III
complex [PMID:12194857]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:12194857]"
/experiment="EXISTENCE:direct assay:GO:0045324 late
endosome to vacuole transport [PMID:12194857]"
/experiment="EXISTENCE:mutant phenotype:GO:0045053 protein
retention in Golgi apparatus [PMID:8649377]"
/experiment="EXISTENCE:mutant phenotype:GO:0070676
intralumenal vesicle formation [PMID:19234443]"
/experiment="EXISTENCE:mutant phenotype:GO:1904669 ATP
export [PMID:26585826]"
/note="Class E Vps protein of the ESCRT-III complex;
required for sorting of integral membrane proteins into
lumenal vesicles of multivesicular bodies, and for
delivery of newly synthesized vacuolar enzymes to the
vacuole, involved in endocytosis"
/codon_start=1
/product="ESCRT-III subunit protein DID4"
/protein_id="DAA09155.1"
/db_xref="SGD:S000001485"
/translation="MSLFEWVFGKNVTPQERLKKNQRALERTQRELEREKRKLELQDK
KLVSEIKKSAKNGQVAAAKVQAKDLVRTRNYIQKFDNMKAQLQAISLRIQAVRSSDQM
TRSMSEATGLLAGMNRTMNLPQLQRISMEFEKQSDLMGQRQEFMDEAIDNVMGDEVDE
DEEADEIVNKVLDEIGVDLNSQLQSTPQNLVSNAPIAETAMGIPEPIGAGSEFHGNPD
DDLQARLNTLKKQT"
gene complement(438777..439385)
/gene="MET14"
/locus_tag="YKL001C"
mRNA complement(438777..439385)
/gene="MET14"
/locus_tag="YKL001C"
/product="adenylyl-sulfate kinase"
CDS complement(438777..439385)
/gene="MET14"
/locus_tag="YKL001C"
/EC_number="2.7.1.25"
/experiment="EXISTENCE:direct assay:GO:0004020
adenylylsulfate kinase activity [PMID:3019265]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:mutant phenotype:GO:0000096 sulfur
amino acid metabolic process [PMID:1101032]"
/experiment="EXISTENCE:mutant phenotype:GO:0004020
adenylylsulfate kinase activity [PMID:197388]"
/experiment="EXISTENCE:mutant phenotype:GO:0019379 sulfate
assimilation, phosphoadenylyl sulfate reduction by
phosphoadenylyl-sulfate reductase (thioredoxin)
[PMID:197388]"
/note="Adenylylsulfate kinase; required for sulfate
assimilation and involved in methionine metabolism; human
homolog PAPSS2 complements yeast null mutant"
/codon_start=1
/product="adenylyl-sulfate kinase"
/protein_id="DAA09156.1"
/db_xref="SGD:S000001484"
/translation="MATNITWHPNLTYDERKALRKQDGCTIWLTGLSASGKSTIACAL
EQLLLQKNLSAYRLDGDNIRFGLNKDLGFSEKDRNENIRRISEVSKLFADSCAISITS
FISPYRVDRDRARELHKEAGLKFIEIFVDVPLEVAEQRDPKGLYKKAREGVIKEFTGI
SAPYEAPKAPELHLRTDQKTVEECATIIYEYLISEKIIRKHL"
centromere complement(440129..440246)
/note="CEN11; Chromosome XI centromere"
/db_xref="SGD:S000006472"
centromere complement(440129..440153)
/note="CEN11_CDEIII of CEN11"
centromere complement(440154..440236)
/note="CEN11_CDEII of CEN11"
centromere complement(440237..440246)
/note="CEN11_CDEI of CEN11"
gene complement(440608..442722)
/gene="VPS1"
/locus_tag="YKR001C"
/gene_synonym="GRD1"
/gene_synonym="LAM1"
/gene_synonym="SPO15"
/gene_synonym="VPL1"
/gene_synonym="VPT26"
mRNA complement(440608..442722)
/gene="VPS1"
/locus_tag="YKR001C"
/gene_synonym="GRD1"
/gene_synonym="LAM1"
/gene_synonym="SPO15"
/gene_synonym="VPL1"
/gene_synonym="VPT26"
/product="dynamin-like GTPase VPS1"
CDS complement(440608..442722)
/gene="VPS1"
/locus_tag="YKR001C"
/gene_synonym="GRD1"
/gene_synonym="LAM1"
/gene_synonym="SPO15"
/gene_synonym="VPL1"
/gene_synonym="VPT26"
/experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
vacuole membrane [PMID:15550248]"
/experiment="EXISTENCE:direct assay:GO:0003924 GTPase
activity [PMID:8299420]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005741
mitochondrial outer membrane [PMID:16407407]"
/experiment="EXISTENCE:direct assay:GO:0005770 late
endosome [PMID:23385815]"
/experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
[PMID:16520372]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0007031 peroxisome
organization [PMID:12707309]"
/experiment="EXISTENCE:direct assay:GO:0030479 actin
cortical patch [PMID:20841380]"
/experiment="EXISTENCE:direct assay:GO:0051015 actin
filament binding [PMID:25772449]"
/experiment="EXISTENCE:direct assay:GO:0060988 lipid tube
assembly [PMID:20841380]"
/experiment="EXISTENCE:genetic interaction:GO:0006897
endocytosis [PMID:20841380]"
/experiment="EXISTENCE:mutant phenotype:GO:0000045
autophagosome assembly [PMID:37060997]"
/experiment="EXISTENCE:mutant phenotype:GO:0000407
phagophore assembly site [PMID:37060997]"
/experiment="EXISTENCE:mutant phenotype:GO:0006623 protein
targeting to vacuole [PMID:8299420]"
/experiment="EXISTENCE:mutant phenotype:GO:0006897
endocytosis [PMID:20841380|PMID:26478779]"
/experiment="EXISTENCE:mutant phenotype:GO:0006914
autophagy [PMID:37060997]"
/experiment="EXISTENCE:mutant phenotype:GO:0007031
peroxisome organization [PMID:12707309]"
/experiment="EXISTENCE:mutant phenotype:GO:0007034
vacuolar transport [PMID:8299420]"
/experiment="EXISTENCE:mutant phenotype:GO:0016559
peroxisome fission [PMID:18445678]"
/experiment="EXISTENCE:mutant phenotype:GO:0030036 actin
cytoskeleton organization [PMID:15265985]"
/experiment="EXISTENCE:mutant phenotype:GO:0034497 protein
localization to phagophore assembly site [PMID:37060997]"
/experiment="EXISTENCE:mutant phenotype:GO:0045053 protein
retention in Golgi apparatus [PMID:8649377]"
/experiment="EXISTENCE:mutant phenotype:GO:0051017 actin
filament bundle assembly [PMID:25772449|PMID:26478779]"
/note="Dynamin-like GTPase required for vacuolar sorting;
promotes fission of retrograde transport carriers from
endosome; also involved in actin cytoskeleton
organization, endocytosis, late Golgi-retention of some
proteins, regulation of peroxisome biogenesis"
/codon_start=1
/product="dynamin-like GTPase VPS1"
/protein_id="DAA09157.1"
/db_xref="SGD:S000001709"
/translation="MDEHLISTINKLQDALAPLGGGSQSPIDLPQITVVGSQSSGKSS
VLENIVGRDFLPRGTGIVTRRPLVLQLINRRPKKSEHAKVNQTANELIDLNINDDDKK
KDESGKHQNEGQSEDNKEEWGEFLHLPGKKFYNFDEIRKEIVKETDKVTGANSGISSV
PINLRIYSPHVLTLTLVDLPGLTKVPVGDQPPDIERQIKDMLLKYISKPNAIILSVNA
ANTDLANSDGLKLAREVDPEGTRTIGVLTKVDLMDQGTDVIDILAGRVIPLRYGYIPV
INRGQKDIEHKKTIREALENERKFFENHPSYSSKAHYCGTPYLAKKLNSILLHHIRQT
LPEIKAKIEATLKKYQNELINLGPETMDSASSVVLSMITDFSNEYAGILDGEAKELSS
QELSGGARISYVFHETFKNGVDSLDPFDQIKDSDIRTIMYNSSGSAPSLFVGTEAFEV
LVKQQIRRFEEPSLRLVTLVFDELVRMLKQIISQPKYSRYPALREAISNQFIQFLKDA
TIPTNEFVVDIIKAEQTYINTAHPDLLKGSQAMVMVEEKLHPRQVAVDPKTGKPLPTQ
PSSSKAPVMEEKSGFFGGFFSTKNKKKLAALESPPPVLKATGQMTERETMETEVIKLL
ISSYFSIVKRTIADIIPKALMLKLIVKSKTDIQKVLLEKLYGKQDIEELTKENDITIQ
RRKECKKMVEILRNASQIVSSV"
gene 443232..444938
/gene="PAP1"
/locus_tag="YKR002W"
mRNA 443232..444938
/gene="PAP1"
/locus_tag="YKR002W"
/product="polynucleotide adenylyltransferase PAP1"
CDS 443232..444938
/gene="PAP1"
/locus_tag="YKR002W"
/EC_number="2.7.7.19"
/experiment="EXISTENCE:direct assay:GO:0005847 mRNA
cleavage and polyadenylation specificity factor complex
[PMID:12819204]"
/experiment="EXISTENCE:direct assay:GO:0031124 mRNA 3'-end
processing [PMID:1840648]"
/experiment="EXISTENCE:direct assay:GO:1990817 poly(A) RNA
polymerase activity [PMID:1840648]"
/experiment="EXISTENCE:genetic interaction:GO:0031126
sno(s)RNA 3'-end processing [PMID:18951092]"
/experiment="EXISTENCE:mutant phenotype:GO:0031124 mRNA
3'-end processing [PMID:8524265]"
/note="Poly(A) polymerase; one of three factors required
for mRNA 3'-end polyadenylation, forms multiprotein
complex with polyadenylation factor I (PF I), also
required for mRNA nuclear export; may also polyadenylate
rRNAs; required for gene looping"
/codon_start=1
/product="polynucleotide adenylyltransferase PAP1"
/protein_id="DAA09158.1"
/db_xref="SGD:S000001710"
/translation="MSSQKVFGITGPVSTVGATAAENKLNDSLIQELKKEGSFETEQE
TANRVQVLKILQELAQRFVYEVSKKKNMSDGMARDAGGKIFTYGSYRLGVHGPGSDID
TLVVVPKHVTREDFFTVFDSLLRERKELDEIAPVPDAFVPIIKIKFSGISIDLICARL
DQPQVPLSLTLSDKNLLRNLDEKDLRALNGTRVTDEILELVPKPNVFRIALRAIKLWA
QRRAVYANIFGFPGGVAWAMLVARICQLYPNACSAVILNRFFIILSEWNWPQPVILKP
IEDGPLQVRVWNPKIYAQDRSHRMPVITPAYPSMCATHNITESTKKVILQEFVRGVQI
TNDIFSNKKSWANLFEKNDFFFRYKFYLEITAYTRGSDEQHLKWSGLVESKVRLLVMK
LEVLAGIKIAHPFTKPFESSYCCPTEDDYEMIQDKYGSHKTETALNALKLVTDENKEE
ESIKDAPKAYLSTMYIGLDFNIENKKEKVDIHIPCTEFVNLCRSFNEDYGDHKVFNLA
LRFVKGYDLPDEVFDENEKRPSKKSKRKNLDARHETVKRSKSDAASGDNINGTTAAVD
VN"
gene 445381..446727
/gene="OSH6"
/locus_tag="YKR003W"
mRNA 445381..446727
/gene="OSH6"
/locus_tag="YKR003W"
/product="oxysterol-binding protein OSH6"
CDS 445381..446727
/gene="OSH6"
/locus_tag="YKR003W"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:16096648]"
/experiment="EXISTENCE:direct assay:GO:0008289 lipid
binding [PMID:20008566]"
/experiment="EXISTENCE:direct assay:GO:0010314
phosphatidylinositol-5-phosphate binding [PMID:16156791]"
/experiment="EXISTENCE:direct assay:GO:0032541 cortical
endoplasmic reticulum [PMID:20008566]"
/experiment="EXISTENCE:direct assay:GO:0043325
phosphatidylinositol-3,4-bisphosphate binding
[PMID:16156791]"
/experiment="EXISTENCE:direct assay:GO:0070273
phosphatidylinositol-4-phosphate binding [PMID:16156791]"
/experiment="EXISTENCE:direct assay:GO:0070300
phosphatidic acid binding [PMID:16156791]"
/experiment="EXISTENCE:direct assay:GO:0080025
phosphatidylinositol-3,5-bisphosphate binding
[PMID:16156791]"
/experiment="EXISTENCE:direct assay:GO:0120015 sterol
transfer activity [PMID:29487131]"
/experiment="EXISTENCE:genetic interaction:GO:0006887
exocytosis [PMID:17004323]"
/experiment="EXISTENCE:genetic interaction:GO:0006897
endocytosis [PMID:15173322]"
/experiment="EXISTENCE:genetic interaction:GO:0015918
sterol transport [PMID:16585271]"
/experiment="EXISTENCE:genetic interaction:GO:0016125
sterol metabolic process [PMID:16096648]"
/experiment="EXISTENCE:genetic interaction:GO:0030011
maintenance of cell polarity [PMID:17004323]"
/experiment="EXISTENCE:genetic interaction:GO:0034727
piecemeal microautophagy of the nucleus [PMID:15367582]"
/experiment="EXISTENCE:mutant phenotype:GO:0055092 sterol
homeostasis [PMID:16156791]"
/note="Oxysterol-binding phosphatidylserine transferase;
family members have overlapping, redundant functions in
sterol metabolism and collectively perform a function
essential for viability; GFP-fusion protein localizes to
the cell periphery; overexpression extends lifespan by
promoting vacuolar fusion; OSH6 has a paralog, OSH7, that
arose from the whole genome duplication"
/codon_start=1
/product="oxysterol-binding protein OSH6"
/protein_id="DAA09159.1"
/db_xref="SGD:S000001711"
/translation="MGSKKLTVGSDSHRLSKSSFSSNKSSHSATKDQPIDTDDIDEDD
ESGHNIILNIISQLRPGCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDP
LKRFLYVMKWYLAGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAYYISEQTSHHPP
ECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLT
QPNVYVRGILFGKMRIELGDHMIIKSPNFQADIEFKTKGYVFGTYDAIEGTVKDYDGN
AYYEISGKWNDVMYLKDLKQPRSSPKVFLDTHKESPLRPKVRPLSEQGEYESRKLWKK
VTDALAVRNHPVATEEKFQIEDHQRQLAKKRIEDGVEFHPKLFRRSKPGEDLDYCIYK
NIPVDEDPEKQIRSILQIAPILPGQQFTDKFFIPAFEKIKSQKKMIENEKQNPAKQ"
gene complement(446799..448036)
/gene="ECM9"
/locus_tag="YKR004C"
/gene_synonym="YKR004C-A"
mRNA complement(join(446799..447706,447811..448036))
/gene="ECM9"
/locus_tag="YKR004C"
/gene_synonym="YKR004C-A"
/product="Ecm9p"
CDS complement(join(446799..447706,447811..448036))
/gene="ECM9"
/locus_tag="YKR004C"
/gene_synonym="YKR004C-A"
/note="Non-essential hypothetical protein"
/codon_start=1
/product="Ecm9p"
/protein_id="DAA09160.1"
/db_xref="SGD:S000001712"
/translation="MQSSLPLCREFFEKITAYLDYHDFRLTITANQPSITLPYYVDEK
AHSIELIIFKTTFLSLFQEAHTYFNKTFSDQSGISNENIYYMTVGFLLTTPENKTVYN
VHEDLLKRYFQDNSVLVIPDLLVKEVRLIQRLLCSSNNRINKSSSLWILYRKLFVLSL
DANTLVLPDILFVFHSSGSQHFSNYYCWNTARWFYDNLPYNKRIELFNLTKRFCFQNV
KDCSSWSALAYMVCQQEEKKTDNIRDFQRLTSSFNVPFKINKVDLNFQVQPADAFTQE
LVKWIDRTYAADWPPYLCLLQITKFNITLRIEMDSVLLTWRNEILNFEENSGHIKMIN
NTPIVPEKFSNDLLTSVNFAHFGYKKLFLNKFLDKNKKEQSDS"
rep_origin 448020..448254
/note="ARS1114; Autonomously Replicating Sequence"
/db_xref="SGD:S000118406"
gene complement(448521..450167)
/locus_tag="YKR005C"
mRNA complement(join(448521..449951,450021..450167))
/locus_tag="YKR005C"
/product="hypothetical protein"
CDS complement(join(448521..449951,450021..450167))
/locus_tag="YKR005C"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:24390141]"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09161.1"
/db_xref="SGD:S000001713"
/translation="MLECLSALLVLFAGGGGSVLAAVQSKTVADPNLCPGYNSQLISP
FLSSCKRNLSECVSRYFDEQYAFCRSCVTVNNETMEDLDNCKCLQCALSSLNNSCFHD
YCTSKDEYDKLQIVVEQFQLTNGVLDDGEILKPRGNKFSSRKLSYFVGQNNTLFRNPL
QFEKNQLISALLTSLTNNQKTISSVDMFEVVDANNEVQYLRERTISGKTLSPATGYEE
ENDGDCSVKDKKWEGKIEYHENKKVSSENCSKDTDDKSGSKKERNTKAPLFHTATEIH
MTRWSSWRPKKIFTRYLVNEYQSPKIITTVNRFYRTKTDTETGTTLITSTKAKRRWFP
RTKIVTSTATSTFLSITTTTTTNAIATKSLVAVLNPDGLNKKAGINFGLFSANGELAS
PDEGGTPTVVRRDKISDPGAANEQATLFSTTFSQVPHLPELDSGEFISAASQLDKRIF
IFTAITVSITTLMMLGFSYRSRVSFRDHSIDDSDDDNDWSDDEVEFDEEYFYSLPVSI
PEKGISLDKMAQQLGVE"
gene complement(450423..451217)
/gene="MRPL13"
/locus_tag="YKR006C"
/gene_synonym="mL50"
/gene_synonym="YK105"
mRNA complement(450423..451217)
/gene="MRPL13"
/locus_tag="YKR006C"
/gene_synonym="mL50"
/gene_synonym="YK105"
/product="mitochondrial 54S ribosomal protein YmL13"
CDS complement(450423..451217)
/gene="MRPL13"
/locus_tag="YKR006C"
/gene_synonym="mL50"
/gene_synonym="YK105"
/experiment="EXISTENCE:curator inference:GO:0032543
mitochondrial translation [PMID:2060626]"
/experiment="EXISTENCE:direct assay:GO:0003735 structural
constituent of ribosome [PMID:2060626]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005762
mitochondrial large ribosomal subunit [PMID:2060626]"
/note="Mitochondrial ribosomal protein of the large
subunit; not essential for mitochondrial translation"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL13"
/protein_id="DAA09162.1"
/db_xref="SGD:S000001714"
/translation="MSSLLKLHCIRPLPQRSVWLSGYKQKARCIHSSAANGDFMSWFK
RKKQEEHQEPVKDTKQLIKDIEEGTNEASSQSSSNNKNRLELIPENFIGEGSRRCKRQ
KELKLAVSSAPFNQWLSRDKITSDNQLDDMILQATEKTLGKVDQDVQFSDLVAKFQFT
KFLQSKSGYLIPDYELTTLSTPLQFKRYIKEKILPSANDPKLAYKEAEPNAIHPFSDN
YASPNIYVVNDVTSKEQKSKYDTIMKEIQKLEDDATRKALETARSA"
gene 451434..451988
/gene="MEH1"
/locus_tag="YKR007W"
/gene_synonym="EGO1"
/gene_synonym="GSE2"
mRNA 451434..451988
/gene="MEH1"
/locus_tag="YKR007W"
/gene_synonym="EGO1"
/gene_synonym="GSE2"
/product="Meh1p"
CDS 451434..451988
/gene="MEH1"
/locus_tag="YKR007W"
/gene_synonym="EGO1"
/gene_synonym="GSE2"
/experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
vacuole membrane
[PMID:14562095|PMID:15885099|PMID:15989961|PMID:16301533|P
MID:19748353]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0031902 late
endosome membrane [PMID:16732272]"
/experiment="EXISTENCE:direct assay:GO:0071986 Ragulator
complex [PMID:16732272]"
/experiment="EXISTENCE:mutant phenotype:GO:0007035
vacuolar acidification [PMID:15885099]"
/experiment="EXISTENCE:mutant phenotype:GO:0016237
microautophagy [PMID:15989961]"
/experiment="EXISTENCE:mutant phenotype:GO:0072665 protein
localization to vacuole [PMID:26206314]"
/experiment="EXISTENCE:physical interaction:GO:0071986
Ragulator complex [PMID:15989961]"
/note="Subunit of EGO/GSE complex; vacuolar/endosomal
membrane-associated EGO/GSE complex regulates exit from
rapamycin-induced growth arrest, stimulating
microautophagy and sorting of Gap1p from endosome to
plasma membrane; targeted to vacuole via AP-3 pathway;
loss results in defect in vacuolar acidification"
/codon_start=1
/product="Meh1p"
/protein_id="DAA09163.1"
/db_xref="SGD:S000001715"
/translation="MGAVLSCCRNHSGEENEALLREQQAGYGSQGNANDEYDAEQMRL
KEHEHEQKLLAREQELRDIVANTNDKLIDISMINNSGIVIQGTDLQEALDKRQQEEGG
DSREDERSAGDDNLSGHSVPSSGSAQATTHQTAPRTNTFTLLTSPDSAKISKEQLKKL
HSNILNEIFSQSQVNKPGPLTVPF"
gene 452201..454078
/gene="RSC4"
/locus_tag="YKR008W"
mRNA 452201..454078
/gene="RSC4"
/locus_tag="YKR008W"
/product="Rsc4p"
CDS 452201..454078
/gene="RSC4"
/locus_tag="YKR008W"
/experiment="EXISTENCE:direct assay:GO:0006337 nucleosome
disassembly [PMID:16492771]"
/experiment="EXISTENCE:direct assay:GO:0006338 chromatin
remodeling [PMID:12183366]"
/experiment="EXISTENCE:direct assay:GO:0006368
transcription elongation by RNA polymerase II
[PMID:17081996]"
/experiment="EXISTENCE:direct assay:GO:0016586 RSC-type
complex [PMID:12183366|PMID:10619019]"
/experiment="EXISTENCE:direct assay:GO:0070577
lysine-acetylated histone binding [PMID:20126658]"
/note="Component of the RSC chromatin remodeling complex;
found in close proximity to nucleosomal DNA; displaced
from the surface of nucleosomal DNA after chromatin
remodeling; acetylated (K25) by Gcn5p, altering
replication stress tolerance; contains tandem bromodomains
that recognize histone H3 acetylated on K14 (H3K14ac) by
Gcn5p"
/codon_start=1
/product="Rsc4p"
/protein_id="DAA09164.2"
/db_xref="SGD:S000001716"
/translation="MVVKKRKLATEAGGSDERPKYLPGKHPKNQEKTPHVDYNAPLNP
KSELFLDDWHIPKFNRFISFTLDVLIDKYKDIFKDFIKLPSRKFHPQYYYKIQQPMSI
NEIKSRDYEYEDGPSNFLLDVELLTKNCQAYNEYDSLIVKNSMQVVMLIEFEVLKAKN
LKRNYLINSEVKAKLLHYLNKLVDATEKKINQALLGASSPKNLDDKVKLSEPFMELVD
KDELPEYYEIVHSPMALSIVKQNLEIGQYSKIYDFIIDMLLVFQNAHIFNDPSALIYK
DATTLTNYFNYLIQKEFFPELQDLNERGEINLEFDKFEFENYLAIGGGGPAAAGALAI
SALDNDIEPESNREDLIDQADYDFNHFEGLGNGYNRSLLTEDYLLNPNNFKKLIAKPE
TVQSEVKNERSTTSDIEKTNSLESEHLKIPKYNVIKSMQKEMQSLSEQHTMEYKPYKL
IQQIYIFSSKNLYSQATKPLLGSRPSCNQNWVEYIFNGNELSQNENAFSFMLQPMQTF
LTLQSHLTSSLKDTETLLTINKEPVKSRTSNVNSNLSQPQQQENDVIGNDTKQDIENL
TIGGGNNNDIVGNDNDKRNNITEIFDIRLSEGLNHLMFRCEDKISHETEFMNFWINVL
P"
gene complement(454352..457054)
/gene="FOX2"
/locus_tag="YKR009C"
/gene_synonym="POX2"
mRNA complement(454352..457054)
/gene="FOX2"
/locus_tag="YKR009C"
/gene_synonym="POX2"
/product="bifunctional hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase FOX2"
CDS complement(454352..457054)
/gene="FOX2"
/locus_tag="YKR009C"
/gene_synonym="POX2"
/EC_number="1.1.1.n12"
/EC_number="4.2.1.119"
/experiment="EXISTENCE:direct assay:GO:0003857
3-hydroxyacyl-CoA dehydrogenase activity [PMID:1551874]"
/experiment="EXISTENCE:direct assay:GO:0004300 enoyl-CoA
hydratase activity [PMID:1551874]"
/experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
[PMID:30131444]"
/experiment="EXISTENCE:mutant phenotype:GO:0006635 fatty
acid beta-oxidation [PMID:10497229|PMID:1551874]"
/note="3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase; multifunctional enzyme of the peroxisomal fatty
acid beta-oxidation pathway; mutation is functionally
complemented by human HSD17B4"
/codon_start=1
/product="bifunctional hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase FOX2"
/protein_id="DAA09165.1"
/db_xref="SGD:S000001717"
/translation="MPGNLSFKDRVVVITGAGGGLGKVYALAYASRGAKVVVNDLGGT
LGGSGHNSKAADLVVDEIKKAGGIAVANYDSVNENGEKIIETAIKEFGRVDVLINNAG
ILRDVSFAKMTEREFASVVDVHLTGGYKLSRAAWPYMRSQKFGRIINTASPAGLFGNF
GQANYSAAKMGLVGLAETLAKEGAKYNINVNSIAPLARSRMTENVLPPHILKQLGPEK
IVPLVLYLTHESTKVSNSIFELAAGFFGQLRWERSSGQIFNPDPKTYTPEAILNKWKE
ITDYRDKPFNKTQHPYQLSDYNDLITKAKKLPPNEQGSVKIKSLCNKVVVVTGAGGGL
GKSHAIWFARYGAKVVVNDIKDPFSVVEEINKLYGEGTAIPDSHDVVTEAPLIIQTAI
SKFQRVDILVNNAGILRDKSFLKMKDEEWFAVLKVHLFSTFSLSKAVWPIFTKQKSGF
IINTTSTSGIYGNFGQANYAAAKAAILGFSKTIALEGAKRGIIVNVIAPHAETAMTKT
IFSEKELSNHFDASQVSPLVVLLASEELQKYSGRRVIGQLFEVGGGWCGQTRWQRSSG
YVSIKETIEPEEIKENWNHITDFSRNTINPSSTEESSMATLQAVQKAHSSKELDDGLF
KYTTKDCILYNLGLGCTSKELKYTYENDPDFQVLPTFAVIPFMQATATLAMDNLVDNF
NYAMLLHGEQYFKLCTPTMPSNGTLKTLAKPLQVLDKNGKAALVVGGFETYDIKTKKL
IAYNEGSFFIRGAHVPPEKEVRDGKRAKFAVQNFEVPHGKVPDFEAEISTNKDQAALY
RLSGDFNPLHIDPTLAKAVKFPTPILHGLCTLGISAKALFEHYGPYEELKVRFTNVVF
PGDTLKVKAWKQGSVVVFQTIDTTRNVIVLDNAAVKLSQAKSKL"
repeat_region complement(458140..458471)
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007058"
gene 458557..458670
/locus_tag="YNCK0016W"
tRNA join(458557..458594,458627..458670)
/locus_tag="YNCK0016W"
/product="tRNA-Leu"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006642"
gene complement(458924..461239)
/gene="TOF2"
/locus_tag="YKR010C"
mRNA complement(458924..461239)
/gene="TOF2"
/locus_tag="YKR010C"
/product="Tof2p"
CDS complement(458924..461239)
/gene="TOF2"
/locus_tag="YKR010C"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:18595708]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0019211 phosphatase
activator activity [PMID:18595708]"
/experiment="EXISTENCE:genetic interaction:GO:0007000
nucleolus organization [PMID:18595708]"
/experiment="EXISTENCE:mutant phenotype:GO:0000183 rDNA
heterochromatin formation [PMID:17043313]"
/experiment="EXISTENCE:mutant phenotype:GO:0007000
nucleolus organization [PMID:18595708]"
/experiment="EXISTENCE:mutant phenotype:GO:0034503 protein
localization to nucleolar rDNA repeats
[PMID:18595708|PMID:19362534]"
/experiment="EXISTENCE:mutant phenotype:GO:0070550 rDNA
chromatin condensation [PMID:18923139]"
/note="Protein required for rDNA silencing and mitotic
rDNA condensation; stimulates Cdc14p phosphatase activity
and biphasic release to promote rDNA repeat segregation;
required for condensin recruitment to the replication fork
barrier site; TOF2 has a paralog, NET1, that arose from
the whole genome duplication"
/codon_start=1
/product="Tof2p"
/protein_id="DAA09166.1"
/db_xref="SGD:S000001718"
/translation="MIKMWRLQIVLVPPSAQDIITFLEARLNTPQSVSPMVQYNEDII
THNNSINNCSDPSPTSPSSQNSIQSNRSSDFINYLPNCKKFLHFTDGDNTLLQLSNEI
LTKFDRLYPNFKESIEIVSLQDRHGCDLDSEFIIKDVFENDGVVLVILKDELDWSRNQ
HISLLQLARQRRRQDNKPSTKSIVTEKRKKISKEDLSSISNKDTMHLIAKSSLKNNFI
NKSRVSTPLMNEILPLASKYDALNKEKCPMPLTSTVVASNVHKDVKDHARAKEGVVTQ
GSDNNKENIPSSTQQQKNDGAKRAESKDLDLLRNSSEDADYEPADENSPQISFDSIDT
DFQLSTTSHTNSDMHIQYSNPSSGAHSPRKSSLEIKVQNKKGDDLPLNDKDIGENCRR
IEAFSDEEDFNETDNDRADSFINNSKKASMGFRDINSDLDSVSFNSDIENAVQSTQST
KNVVSPPFFPEKELNNRLHQSQGKEALFRLVEKEFPDKSLGAASSTSHAKDVKIQETI
RKLNRFKPTGETKVQKRNSITEPYYGKFGIMKKDKPKSITSKGVSLETKHFDDPNTII
SGEKFAKFGKIKVKRKTDDVGSKVIEFKRKRNMGNRSLKDIFANAGKPPNAASTIKVV
KLMRDPVDNSKDKVEATSNSTAQEQEQVSPKLPVMNSTPGKRKNGQAIPSSLERTPQL
KKVKVTRSHSSPSSSSSMSLESSLDSSSSDDSDDDSDSRNVQVKKINFKTSHGPAGNS
NGKPMLDVDDNEINTKKYQTPKYVESDEDDQ"
gene complement(461635..462696)
/gene="FPT1"
/locus_tag="YKR011C"
mRNA complement(461635..462696)
/gene="FPT1"
/locus_tag="YKR011C"
/product="chromatin-associated RNAPIII regulator FPT1"
CDS complement(461635..462696)
/gene="FPT1"
/locus_tag="YKR011C"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0031669 cellular
response to nutrient levels [PMID:37995691]"
/experiment="EXISTENCE:direct assay:GO:0071443 tDNA
binding [PMID:37995691]"
/experiment="EXISTENCE:mutant phenotype:GO:1903623
negative regulation of RNA polymerase III activity
[PMID:37995691]"
/note="Chromatin-associated negative regulator of RNA
polymerase III assembly; differentially and dynamically
occupies RNA polymerase III-transcribed genes; promotes
eviction of RNAPIII; occupancy depends on TFIIIB and
TFIIIC, not RNAPIII; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="chromatin-associated RNAPIII regulator FPT1"
/protein_id="DAA09167.1"
/db_xref="SGD:S000001719"
/translation="MSKLETVYLYAGEEQPRVKLTCIKEGLTLTQVIKFVHSIQELYG
IELQTSETITENLKIDCAPAYLKPNCIPHFYILEYEEISDTFFIWKSDGRWQLNKLSA
LLYVDNDANVVKNTSWKEVFQNDQRFKNYDKRAWLQNCLEKMNRDLSKLNVEQFWSQY
DKICQSIAKQKKKQEQFNMEVFDNFKNIVSIAIIKTKVLSNKRLLTTTLKNYHNSMKK
KYNIQEQNLKENSLASCSNNEPSASLESESRHFSPVNSLSPSSLSTDDEAVSTDYIYK
GPESKPNVNFMHSSATNDLIKSNFESYFKLMAEDYETFDLRAWSRQRPRKFQLVEKKK
ITKNPPNSHHPHKNGKISF"
rep_origin 462699..463742
/note="ARS1115; Putative replication origin; identified in
multiple array studies, not yet confirmed by plasmid-based
assay"
/db_xref="SGD:S000130139"
gene 463959..464948
/gene="PRY2"
/locus_tag="YKR013W"
/gene_synonym="YFW12"
mRNA 463959..464948
/gene="PRY2"
/locus_tag="YKR013W"
/gene_synonym="YFW12"
/product="sterol-binding protein"
CDS 463959..464948
/gene="PRY2"
/locus_tag="YKR013W"
/gene_synonym="YFW12"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005576
extracellular region [PMID:11935221]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0032934 sterol
binding [PMID:23027975]"
/experiment="EXISTENCE:genetic interaction:GO:0015908
fatty acid transport [PMID:28365570]"
/experiment="EXISTENCE:genetic interaction:GO:0015918
sterol transport [PMID:23027975]"
/experiment="EXISTENCE:mutant phenotype:GO:0015918 sterol
transport [PMID:23027975]"
/note="Sterol binding protein involved in the export of
acetylated sterols; role in sterol export is redundant
with that of PRY1; redundant role with PRY1 and PRY3 in
the export of free fatty acids; may be involved in
detoxification of hydrophobic compounds; secreted
glycoprotein and member of the CAP protein superfamily
(cysteine-rich secretory proteins (CRISP), antigen 5, and
pathogenesis related 1 proteins)"
/codon_start=1
/product="sterol-binding protein"
/protein_id="DAA09168.1"
/db_xref="SGD:S000001721"
/translation="MKFSKVSLLAASASVALSAPVAVTVTQHVHQAATVVVQGIVRVE
NGQTLTTFITKGTQTASASPVATTSAPIVVANAQVDSIATSVIQESAVVAESATFEES
STETSEAFSTATATIQAVQTSASATQDDVTTTLTSSTQPTSTTTPTTTTTSPTTTTSP
TTTASPTTTASPTTATTTQSTASSTQSSSSDFSTSMVNEHNTKRALHKDTGSLTWSDT
LATYAQNYADSYDCSGNLVHSGGPYGENLALGYGTTGSVDAWYNEITSYDYSNPGFSE
SAGHFTQVVWKGTSEVGCGLKSCGGEWGDYIICSYKAAGNVIGEFADNVMPLA"
gene complement(465367..466071)
/gene="YPT52"
/locus_tag="YKR014C"
mRNA complement(465367..466071)
/gene="YPT52"
/locus_tag="YKR014C"
/product="Rab family GTPase YPT52"
CDS complement(465367..466071)
/gene="YPT52"
/locus_tag="YKR014C"
/experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
vacuole membrane [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0003924 GTPase
activity [PMID:11210571]"
/experiment="EXISTENCE:genetic interaction:GO:0006895
Golgi to endosome transport [PMID:22748138|PMID:23612966]"
/experiment="EXISTENCE:genetic interaction:GO:0032511 late
endosome to vacuole transport via multivesicular body
sorting pathway [PMID:22748138]"
/experiment="EXISTENCE:genetic interaction:GO:0036010
protein localization to endosome [PMID:23264632]"
/experiment="EXISTENCE:genetic interaction:GO:0036258
multivesicular body assembly [PMID:22748138]"
/experiment="EXISTENCE:mutant phenotype:GO:0003924 GTPase
activity [PMID:8163546]"
/experiment="EXISTENCE:mutant phenotype:GO:0005770 late
endosome [PMID:11872141]"
/experiment="EXISTENCE:mutant phenotype:GO:0006623 protein
targeting to vacuole [PMID:8163546]"
/experiment="EXISTENCE:mutant phenotype:GO:0006895 Golgi
to endosome transport [PMID:22748138]"
/experiment="EXISTENCE:mutant phenotype:GO:0006897
endocytosis [PMID:8163546]"
/note="Endosomal Rab family GTPase; required for vacuolar
protein sorting, endocytosis and multivesicular body (MVB)
biogenesis and sorting; required for localization of the
CORVET complex to endosomes; involved in autophagy and
ionic stress tolerance; similar to Vps21p and Ypt53p;
mammalian Rab5 homolog; protein abundance increases in
response to DNA replication stress"
/codon_start=1
/product="Rab family GTPase YPT52"
/protein_id="DAA09169.1"
/db_xref="SGD:S000001722"
/translation="MLQFKLVLLGDSSVGKSSIVHRFVKDTFDELRESTIGAAFLSQS
ITIHPNDGNETKDVVIKFEIWDTAGQERYKSLAPMYYRNANAALVVYDITQEDSLQKA
RNWVDELKNKVGDDDLVIYLLGNKVDLCQETPSTETSPDSNEGGDEEQKVRAISTEEA
KQYAQEQGLLFREVSAKTGEGVKEIFQDIGEKLYDLKKDEILSKQNRQIGGGNNGQVD
INLQRPSTNDPTSCCS"
gene complement(466961..468667)
/locus_tag="YKR015C"
mRNA complement(466961..468667)
/locus_tag="YKR015C"
/product="hypothetical protein"
CDS complement(466961..468667)
/locus_tag="YKR015C"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09170.1"
/db_xref="SGD:S000001723"
/translation="MFLDYSGYEALTEINSSFGKYVLLLQQFEGCRSLKDRLQMLKDL
GREFMIFENLNVEDFRESKNMIHRFYTMVISLRQIMEIGPLVRRSPAVLVVEFDCPVE
DCLDELDPLHPLNRAFIFIHKQWTYYHQYYIVEKVKKVILDMAPVKEDDWSILHKVVY
SEGFVERRYKKKKYLGDIYIPQPLMKSNKITTISNFSQLTKISNVRVYRFNATAACDP
QNLNKKNLSIKELKDKDLPNLIWTLEPEKFYVDMRPYKEHEERKKRREEEAKVRMQGE
EQENIMIERKKMDSIEVEASSGLKNIIKTPLANRVVNTFNNCAAVVIGYVTEVDKVKD
DNEEKNNDRPKIANDGIAQKSRSESEDNAGTPMENAYFQPEPQDNDQNNISWNTTMKD
IDPIYMSERCARVWRKEQQMLGLEKAQTFEKKYCKDQMVMDENQVEEPGKHSERHTKN
QVVRPRTKIASSASKNDNSNNKNSKSCKNCHKEEAHGLVREYLKIKLNISPHGERNQR
TKDKRKCIMKYNASSNNINKMPGESEVLGSTILTDIHFKDVVTVKFRDFKAKFRKVKI
NA"
gene 469717..471339
/gene="MIC60"
/locus_tag="YKR016W"
/gene_synonym="AIM28"
/gene_synonym="FCJ1"
/gene_synonym="FMP13"
mRNA 469717..471339
/gene="MIC60"
/locus_tag="YKR016W"
/gene_synonym="AIM28"
/gene_synonym="FCJ1"
/gene_synonym="FMP13"
/product="Mic60p"
CDS 469717..471339
/gene="MIC60"
/locus_tag="YKR016W"
/gene_synonym="AIM28"
/gene_synonym="FCJ1"
/gene_synonym="FMP13"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion
[PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005743
mitochondrial inner membrane [PMID:19528297]"
/experiment="EXISTENCE:direct assay:GO:0030061
mitochondrial crista [PMID:19528297]"
/experiment="EXISTENCE:direct assay:GO:0044284
mitochondrial crista junction [PMID:22009199]"
/experiment="EXISTENCE:direct assay:GO:0061617 MICOS
complex [PMID:21944719|PMID:21987634|PMID:22009199]"
/experiment="EXISTENCE:mutant phenotype:GO:0042407 cristae
formation
[PMID:19528297|PMID:21944719|PMID:21987634|PMID:22009199]"
/experiment="EXISTENCE:mutant phenotype:GO:0045041 protein
import into mitochondrial intermembrane space
[PMID:21944719]"
/experiment="EXISTENCE:physical interaction:GO:0045041
protein import into mitochondrial intermembrane space
[PMID:21944719]"
/note="Component of the MICOS complex; MICOS (formerly
MINOS or MitOS) is a mitochondrial inner membrane complex
that extends into the intermembrane space and has a role
in the maintenance of crista junctions, inner membrane
architecture, and formation of contact sites to the outer
membrane; Mic60p is also involved in import of
intermembrane space (IMS) proteins, probably by
positioning Mia40p relative to the TOM complex to receive
incoming proteins; ortholog of mammalian mitofilin"
/codon_start=1
/product="Mic60p"
/protein_id="DAA09171.1"
/db_xref="SGD:S000001724"
/translation="MMLRTTASRKIVLRRGLASINTGTTVASKKASHKFRNTLWTIAL
SATAFYAGGIIYSQKNDKFGDFFSNNVPFAEDLLETYEHYHDRPTLFLEDSWDGLKAK
SNDLLSGLTGSSQTRRSNRENIEVKKILSLEPLNIETENSDPQLKEIIGSLNDLINSL
NDSNLSIPESEFNSIKKSNQNMLTNLSQLNETLKEALSNYMIQRTSEVITELNTQYEN
SKREFEKNLQKNLLQEVDEFKENLTKQKDKELEEKLKANEELLQAKHANEVGLLSITQ
VKEFNKIIKDKIEKERNGRLAHLEEINSEVNDLSKSIDRSSKILSKNEALVQLTFQVD
EIKSRINNNNLPDVNIDKELSRLKLLSNLLSTFNKKSCCDDGDCCSCKKGNKNEGKEG
KISCKCKPKTNPPSLLSVALDELESTCSGKKILSNEQIYNRWNLLADDFKTASLLPPN
SGILGQLTAKVFSLFLFTKTGNPSNATDFDSVYARVGDNLRVSNLNDAVEEVVSLKGW
PHKVCESWIEDARRKLEVQRLVEILDCEIRTL"
gene complement(471694..473349)
/gene="HEL1"
/locus_tag="YKR017C"
mRNA complement(471694..473349)
/gene="HEL1"
/locus_tag="YKR017C"
/product="E3 ubiquitin-protein ligase HEL1"
CDS complement(471694..473349)
/gene="HEL1"
/locus_tag="YKR017C"
/EC_number="2.3.2.31"
/experiment="EXISTENCE:direct assay:GO:0061630 ubiquitin
protein ligase activity [PMID:22570702]"
/experiment="EXISTENCE:mutant phenotype:GO:0036205 histone
catabolic process [PMID:22570702]"
/note="RING finger ubiquitin ligase (E3); involved in
ubiquitination and degradation of excess histones;
interacts with Ubc4p and Rad53p; null mutant sensitive to
hydroxyurea (HU)"
/codon_start=1
/product="E3 ubiquitin-protein ligase HEL1"
/protein_id="DAA09172.1"
/db_xref="SGD:S000001725"
/translation="MSSGTENDQFYSFDESDSSSIELYESHNTSEFTIHGLVFPKLIS
VTSQDSEFDINEDEDGVDTIYEGMLDAPLTKNNKRILCEGSVPNLSYECLTTKGIFER
MLQRVDHLQPIFAIPSADILILLQHYDWNEERLLEVWTEKMDELLVELGLSTTANIKK
DNDYNSHFREVEFKNDFTCIICCDKKDTETFALECGHEYCINCYRHYIKDKLHEGNII
TCMDCSLALKNEDIDKVMGHPSSSKLMDSSIKSFVQKHNRNYKWCPFADCKSIVHLRD
TSSLPEYTRLHYSPFVKCNSFHRFCFNCGFEVHSPADCKITTAWVKKARKESEILNWV
LSHTKECPKCSVNIEKNGGCNHMVCSSCKYEFCWICEGPWAPHGKNFFQCTMYKNNED
NKSKNPQDANKTLKKYTFYYRLFNEHEVSAKLDWNLGQTLGTKVHALQERIGISWIDG
QFLSESLKVLNEGRTVLKWSFAVAYYSDASHNLTKIFVDNQMLLANAVESLSELLQIK
TPEVIMKRRPEFYNKAGYVENRTTALMECGRELLCKGICKAAE"
gene complement(473723..475900)
/locus_tag="YKR018C"
mRNA complement(473723..475900)
/locus_tag="YKR018C"
/product="hypothetical protein"
CDS complement(473723..475900)
/locus_tag="YKR018C"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/note="hypothetical protein; green fluorescent protein
(GFP)-fusion protein localizes to the cytoplasm and
nucleus; protein abundance increases in response to DNA
replication stress; YKR018C has a paralog, IML2, that
arose from the whole genome duplication"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09173.1"
/db_xref="SGD:S000001726"
/translation="MFKVFGFGAKEEIPELSQEEKTKAILKQAHDFEQALRAMDYVLD
DNADEGLALLDESDAKEASDQTINALARGVIEFLEATLGFEAEEMKKASATLAKAEAL
SLKSRERAQKIGLKSSSLYPPGTVYAVTYTESCLLHALLMIFSESMMEAAKAILKLRK
SYYMLQEILETIKAANKAKKLKITSGSEDKESTPATFITGGDAFNSVDIPYELTPEEQ
KDKDLLQFAEQIHSMRTERLSGAHIGNSPAINRLRGELGLQAMEDLPEEEITDHKVLS
DDIDLSQATIDEFVHSGVNLCFGILQVVISLLPPAIGAVLSVVGFRGSREEGLRLVWK
ATKQRNVHGCIGLLALMFYYDGPFQFTDDDFDIPAAVKDSSNSEDSEDEEMDGPTLLH
PGKILEDALLQSRALFPNSALWLLNEARMLSGKGRLEEAVALMDSIDVSKIRMRQVKS
LMIFDRAITLIHLHQYDRAAEDILSLLDISDWSHAFYTYFAGCCYLENWRMCEMGLMK
SDKKDEYQKKAEELIFTSVNLLGKKTFKSKNLPLDRFILRKVEQFKAKKEELGVENPL
DGIATSPVHEIAYFYNGYNRMSEEHLELTKKMLTEYRNPAIEALDSDQELIKDLLVSL
TLRRLGHIQEGCDILDEKVLPKFFSIQNGKVKYIKKTEDPWAYPTALYERALFTWKLE
GMDGLPESKEWLLRAQGYADDYELSTRVGMKIKAAIDRVDHSL"
gene complement(476216..478063)
/gene="IRS4"
/locus_tag="YKR019C"
mRNA complement(476216..478063)
/gene="IRS4"
/locus_tag="YKR019C"
/product="Irs4p"
CDS complement(476216..478063)
/gene="IRS4"
/locus_tag="YKR019C"
/experiment="EXISTENCE:direct assay:GO:0000407 phagophore
assembly site [PMID:18298591]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:genetic interaction:GO:0006914
autophagy [PMID:18298591]"
/experiment="EXISTENCE:genetic interaction:GO:0031505
fungal-type cell wall organization [PMID:15265867]"
/experiment="EXISTENCE:mutant phenotype:GO:0000183 rDNA
heterochromatin formation [PMID:10082585]"
/note="EH domain-containing protein; involved in
regulating phosphatidylinositol 4,5-bisphosphate levels
and autophagy; Irs4p and Tax4p bind and activate the
PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in
localizing Atg17p to the PAS; IRS4 has a paralog, TAX4,
that arose from the whole genome duplication"
/codon_start=1
/product="Irs4p"
/protein_id="DAA09174.1"
/db_xref="SGD:S000001727"
/translation="MRLSFGKQRYHGGTTVTLTEQGASDSLRAAQAIFQNHSNEVSSP
CPPVTVSRNPQTRLSEPSLQKSGRKQEQKKARIRTKQVPKIKTTAPNDVELSKKHRSS
PAGKDNVSSTAQMAAALAHSQSKLSSDNNSSHSSALDTLKVLETPNLNGLLGIHSRSS
SRNGSNESLTPGQRTPDNRSQENLLTSFSSGRRLSSSSMEPATNKDSNKALPKRRPSP
PLQSSLVGSGQLHENENLSSISIDSRHSLNPDTSDVISNRSQTSLSQTINQLSLCESE
PSIASSNTTTTTSNQGSGLPNLVPNYSSDMRKKKLVNKFKRKVFGSKPKHLSSQYEMD
ASSEELGQHEQQPSMRFKTTLRKTSVSTNAENDHASSLHEGNLRYKYNPSNDTYDVYD
DTDSDSESDQNQDALTKPRKRDRIKRKIRNSANKTAHHRPIHRTRDRKFNEDKPWKSH
TDITFVTDNERKRYESMWVSNRHRHLNLLSWWPSITGDSGAINTLPEDGLILGIIVRD
IWKRSNLPNSLLAEIYTKVDTRKDGTLDRKSFIVGMWLVDQCLYGRKLPNVVEQCVWD
SVDRYASTTVVPVSTLKAMAKQKRKQMKEEIKNIKKENRVVLVDHNSSS"
gene 478338..478832
/gene="VPS51"
/locus_tag="YKR020W"
/gene_synonym="API3"
/gene_synonym="VPS67"
/gene_synonym="WHI6"
mRNA 478338..478832
/gene="VPS51"
/locus_tag="YKR020W"
/gene_synonym="API3"
/gene_synonym="VPS67"
/gene_synonym="WHI6"
/product="Vps51p"
CDS 478338..478832
/gene="VPS51"
/locus_tag="YKR020W"
/gene_synonym="API3"
/gene_synonym="VPS67"
/gene_synonym="WHI6"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:12377769]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0007118 budding
cell apical bud growth [PMID:11957109]"
/experiment="EXISTENCE:direct assay:GO:0042147 retrograde
transport, endosome to Golgi [PMID:12686613]"
/experiment="EXISTENCE:mutant phenotype:GO:0006623 protein
targeting to vacuole [PMID:12134085]"
/experiment="EXISTENCE:mutant phenotype:GO:0008361
regulation of cell size [PMID:12089449]"
/experiment="EXISTENCE:mutant phenotype:GO:0016050 vesicle
organization [PMID:12446664]"
/experiment="EXISTENCE:mutant phenotype:GO:0016239
positive regulation of macroautophagy [PMID:12446664]"
/experiment="EXISTENCE:mutant phenotype:GO:0090156
intracellular sphingolipid homeostasis [PMID:26357016]"
/experiment="EXISTENCE:physical interaction:GO:0000938
GARP complex [PMID:12377769|PMID:12446664]"
/experiment="EXISTENCE:physical interaction:GO:0005515
protein binding [PMID:12377769]"
/note="Component of the GARP (Golgi-associated retrograde
protein) complex; GARP is required for the recycling of
proteins from endosomes to the late Golgi, and for mitosis
after DNA damage induced checkpoint arrest; links the
(VFT/GARP) complex to the SNARE Tlg1p; members of the GARP
complex are Vps51p-Vps52p-Vps53p-Vps54p"
/codon_start=1
/product="Vps51p"
/protein_id="DAA09175.1"
/db_xref="SGD:S000001728"
/translation="MAEQISHKKSLRVSSLNKDRRLLLREFYNLENEPNKGRQEARIG
EKASEAHSGEEQVTDVNIDTEANTEKPVKDDELSATEEDLKEGSEDAEEEIKNLPFKR
LVQIHNKLLGKETETNNSIKNTIYENYYDLIKVNDLLKEITNANEDQINKLKQTVESL
IKEL"
gene 479234..481981
/gene="ALY1"
/locus_tag="YKR021W"
/gene_synonym="ART6"
mRNA 479234..481981
/gene="ALY1"
/locus_tag="YKR021W"
/gene_synonym="ART6"
/product="Aly1p"
CDS 479234..481981
/gene="ALY1"
/locus_tag="YKR021W"
/gene_synonym="ART6"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005769 early
endosome [PMID:20739461]"
/experiment="EXISTENCE:direct assay:GO:0005770 late
endosome [PMID:20739461]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:genetic interaction:GO:2000397
positive regulation of ubiquitin-dependent endocytosis
[PMID:20956561]"
/experiment="EXISTENCE:mutant phenotype:GO:0006897
endocytosis [PMID:23824189]"
/experiment="EXISTENCE:mutant phenotype:GO:0032386
regulation of intracellular transport [PMID:20739461]"
/experiment="EXISTENCE:physical interaction:GO:0031625
ubiquitin protein ligase binding [PMID:18976803]"
/note="Alpha arrestin, substrate of calcineurin; controls
nutrient-mediated intracellular sorting of permease Gap1p;
interacts with AP-1 subunit Apl4p; dephosphorylation of
Aly1p required for the endocytosis of Dip5p; may regulate
endocytosis of plasma membrane proteins by recruiting
ubiquitin ligase Rsp5p to plasma membrane targets;
regulates intracellular pH; ALY1 has a paralog, ALY2, that
arose from the whole genome duplication"
/codon_start=1
/product="Aly1p"
/protein_id="DAA09176.1"
/db_xref="SGD:S000001729"
/translation="MLQFNTENDTVAPVFPMEQDINAAPDAVPLVQTTTLQVFVKLAE
PIVFLKGFETNGLSEIAPSILRGSLIVRVLKPNKLKSISITFKGISRTEWPEGIPPKR
EEFSDVETVVNHTWPFYQADDGMNSFTLEHHSSNNSSNRPSMSDEDYLLEKSGASVYI
PPTAEPPKDNSNLSLDAYERNSLSSDNLSNKPVSSDVSHDDSKLLAIQKTPLPSSSRR
GSVPANFHGNSLSPHTFISDLFTKTFSNSGATPSPEQEDNYLTPSKDSKEVFIFRPGD
YIYTFEQPISQSYPESIKANFGSVEYKLSIDIERFGAFKSTIHTQLPIKVVRLPSDGS
VEETEAIAISKDWKDLLHYDVVIFSKEIVLNAFLPIDFHFAPLDKVTLHRIRIYLTES
MEYTCNSNGNHEKARRLEPTKKFLLAEHNGPKLPHIPAGSNPLKAKNRGNILLDEKSG
DLVNKDFQFEVFVPSKFTNSIRLHPDTNYDKIKAHHWIKICLRLSKKYGDNRKHFEIS
IDSPIHILNQLCSHANTLLPSYESHFQYCDEDGNFAPAADQQNYASHHDSNIFFPKEV
LSSPVLSPNVQKMNIRIPSDLPVVRNRAESVKKSKSDNTSKKNDQSSNVFASKQLVAN
IYKPNQIPRELTSPQALPLSPITSPILNYQPLSNSPPPDFDFDLAKRGAADSHAIPVD
PPSYFDVLKADGIELPYYDTSSSKIPELKLNKSRETLASIEEDSFNGWSQIDDLSDED
DNDGDIASGFNFKLSTSAPSENVNSHTPILQSLNMSLDGRKKNRASLHATSVLPSTIR
QNNQHFNDINQMLGSSDEDAFPKSQSLNFNKKLPILKINDNVIQSNSNSNNRVDNPED
TVDSSVDITAFYDPRMSSDSKFDWEVSKNHVDPAAYSVNVASENRVLDDFKKAFREKR
K"
gene complement(482171..483139)
/gene="NTR2"
/locus_tag="YKR022C"
mRNA complement(482171..483139)
/gene="NTR2"
/locus_tag="YKR022C"
/product="Ntr2p"
CDS complement(482171..483139)
/gene="NTR2"
/locus_tag="YKR022C"
/experiment="EXISTENCE:direct assay:GO:0000390
spliceosomal complex disassembly
[PMID:16357217|PMID:16880513]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095|PMID:14690591]"
/experiment="EXISTENCE:direct assay:GO:0005681
spliceosomal complex [PMID:16880513]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0071008 U2-type
post-mRNA release spliceosomal complex [PMID:16357217]"
/experiment="EXISTENCE:mutant phenotype:GO:0000390
spliceosomal complex disassembly [PMID:16880513]"
/note="Essential protein that forms a dimer with Ntr1p;
also forms a trimer, with Ntr2p and the DExD/H-box RNA
helicase Prp43p, that is involved in spliceosome
disassembly"
/codon_start=1
/product="Ntr2p"
/protein_id="DAA09177.1"
/db_xref="SGD:S000001730"
/translation="MAIKKRNKIRLPSGSPEEVGIDGSAHKPMQQIKPLVSNDSEDDD
NDICVLQPIKFKKVPKRDITFDGEQAIKEDNSHYEDLYHSKKNTNASTRNKDDLLILN
MEDLMEGNHHLLSDSSEAGSSSEGEHISSIPTRGEIAKLKAQKSLSRRKISESDVTTE
RDYVKLLDSEDKREIMETIRLNGGLKRNNEKEITNFSDDEMQGFQDEMLALTDNQIAI
QKDSKRKIIEKAINEVPYRTNEEWETQLLSKGNINKSNEKIITPLPVLFPDDDESGNS
IERINEMVSKICLQRKKVEMRLQALEKTKIDLEKSKASLINKLIGN"
gene 483419..485011
/gene="RQT4"
/locus_tag="YKR023W"
mRNA 483419..485011
/gene="RQT4"
/locus_tag="YKR023W"
/product="Rqt4p"
CDS 483419..485011
/gene="RQT4"
/locus_tag="YKR023W"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0022626 cytosolic
ribosome [PMID:36627279]"
/experiment="EXISTENCE:direct assay:GO:0070530 K63-linked
polyubiquitin modification-dependent protein binding
[PMID:36627279]"
/experiment="EXISTENCE:direct assay:GO:0072344 rescue of
stalled ribosome [PMID:36627279]"
/experiment="EXISTENCE:mutant phenotype:GO:1990116
ribosome-associated ubiquitin-dependent protein catabolic
process [PMID:28757607]"
/note="Subunit of ribosome-associated quality control
trigger complex (RQT); the authentic, non-tagged protein
is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="Rqt4p"
/protein_id="DAA09178.1"
/db_xref="SGD:S000001731"
/translation="MTRKQAIDYAIKQVPQILPLEESDVKALCEQVLSTSSDDPEQIA
SKFLEFLGHEDLSFEFVMKFNELLNQNDKKEEKKTKNVHLEHTAPTSWKNESKQPTNN
YINKKGDEKPKKLKDEKKSSTTRPTVQPSNQSTQSNPIKEKKEHRSKGKLQSLQEIDE
AIKMLELRDSGSSKNCNCQGTRHPVFDIAPNCLHCGKVVCVIEGLNKGKCGHCHEQLI
SDNERTQMVEILNQEKNELNGSSSSLSNASNGANVPKKKTKTYKITSGMGKNLFAEQD
KLFDFIERKRERERKRNEVLKLQEEKEESEAKERQASEHDHKAEENPELLAAQERLDR
LLYFQDTSAERTKIIDNASDFDMNQEVGLWGSARERALALKKQQRNLRKWEKVEKERN
GRREKYVVSMNIGSNGKVTMTEVPKDTENVIAGSDDDISDISDEEDISDLKHIHALKS
EINTTKSLENLHLQSKAWDYERDKKQFDRPTYVKKNSDTAQQNRKTEEKAHDMQAYDL
KSRVQVDQNADASVEQNILAVL"
gene complement(485144..487372)
/gene="DBP7"
/locus_tag="YKR024C"
mRNA complement(485144..487372)
/gene="DBP7"
/locus_tag="YKR024C"
/product="putative ATP-dependent RNA helicase"
CDS complement(485144..487372)
/gene="DBP7"
/locus_tag="YKR024C"
/EC_number="3.6.4.13"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:9582098]"
/experiment="EXISTENCE:mutant phenotype:GO:0000463
maturation of LSU-rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:9582098]"
/experiment="EXISTENCE:mutant phenotype:GO:0000464
endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA
from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA) [PMID:34686661]"
/note="Putative ATP-dependent RNA helicase of the DEAD-box
family; involved in ribosomal biogenesis; required at
post-transcriptional step for efficient
retrotransposition; essential for growth under anaerobic
conditions"
/codon_start=1
/product="putative ATP-dependent RNA helicase"
/protein_id="DAA09179.1"
/db_xref="SGD:S000001732"
/translation="MSDEDSMLLNFTTNEDTAGSSYKQAAKVTGGRWKDRRRMKMKLE
GKTVSRKRKANTTGDEGIIPGRGENSIKKLHKESSYSSEEQEKYKGRNAHNTQGRTLP
ADSQFVSSLFTSNREITTAVNTNIHDENVAINPSNAPLKGDQFASLGVSSLLVSHLEQ
KMRIKKPTSIQKQAIPQIIGNAGKNDFFIHAQTGSGKTLSYLLPIISTILNMDTHVDR
TSGAFALVIAPTRELASQIYHVCSTLVSCCHYLVPCLLIGGERKKSEKARLRKGCNFI
IGTPGRVLDHLQNTKVIKEQLSQSLRYIVLDEGDKLMELGFDETISEIIKIVHDIPIN
SEKFPKLPHKLVHMLCSATLTDGVNRLRNVALKDYKLISNGTKKDSDIVTVAPDQLLQ
RITIVPPKLRLVTLAATLNNITKDFIASGQQSKTLRTIVFVSCSDSVEFHYDAFSGSD
GHHKNLTGDSVRLLTKGNTMFPCFSDSRDPDVVIYKLHGSLSQQMRTSTLQHFARDNE
ATKGKHLIMFCTDVASRGLDLPHVGSVIELDPPFAVEDHLHRVGRTARAGEKGESLLF
LLPGEEEKYMDYIQPYHPMGWELLKFDKEILMPAFKDVNVNRNDKFIRKDEKSSKNKD
VGDKEYEWDTNATTWHLNIERRVVGDSAFKNLAVKGFISHVRAYATHISQEKKFFNVK
FLHLGHLAKSFGLRERPKAMGLQSSKDGNSEKKPTKENSKNKMFRMARMAEKQIASEF
NY"
gene 487770..488618
/gene="RPC37"
/locus_tag="YKR025W"
mRNA 487770..488618
/gene="RPC37"
/locus_tag="YKR025W"
/product="DNA-directed RNA polymerase III subunit C37"
CDS 487770..488618
/gene="RPC37"
/locus_tag="YKR025W"
/experiment="EXISTENCE:direct assay:GO:0001056 RNA
polymerase III activity [PMID:3905793]"
/experiment="EXISTENCE:direct assay:GO:0005666 RNA
polymerase III complex [PMID:10611227|PMID:3905793]"
/experiment="EXISTENCE:direct assay:GO:0042797 tRNA
transcription by RNA polymerase III [PMID:3905793]"
/note="RNA polymerase III subunit C37"
/codon_start=1
/product="DNA-directed RNA polymerase III subunit C37"
/protein_id="DAA09180.1"
/db_xref="SGD:S000001733"
/translation="MSIDNKLFVTEEDEEDRTQDRADVEDESNDIDMIADENGTNSAI
ANEQEEKSEEVKAEDDTGEEEEDDPVIEEFPLKISGEEESLHVFQYANRPRLVGRKPA
EHPFISAARYKPKSHLWEIDIPLDEQAFYNKDKAESEWNGVNVQTLKGVGVENNGQYA
AFVKDMQVYLVPIERVAQLKPFFKYIDDANVTRKQEDARRNPNPSSQRAQVVTMSVKS
VNDPSQNRLTGSLLAHKVADEEANIELTWAEGTFEQFKDTIVKEAEDKTLVALEKQED
YIDNLV"
gene complement(488738..489655)
/gene="GCN3"
/locus_tag="YKR026C"
/gene_synonym="AAS2"
mRNA complement(488738..489655)
/gene="GCN3"
/locus_tag="YKR026C"
/gene_synonym="AAS2"
/product="translation initiation factor eIF2B subunit
alpha"
CDS complement(488738..489655)
/gene="GCN3"
/locus_tag="YKR026C"
/gene_synonym="AAS2"
/experiment="EXISTENCE:direct assay:GO:0003743 translation
initiation factor activity [PMID:8336705]"
/experiment="EXISTENCE:direct assay:GO:0005085
guanyl-nucleotide exchange factor activity [PMID:8506384]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005851 eukaryotic
translation initiation factor 2B complex
[PMID:8506384|PMID:8336705]"
/experiment="EXISTENCE:direct assay:GO:0006446 regulation
of translational initiation [PMID:8506384]"
/experiment="EXISTENCE:direct assay:GO:0032045
guanyl-nucleotide exchange factor complex [PMID:8506384]"
/experiment="EXISTENCE:genetic interaction:GO:0006446
regulation of translational initiation [PMID:8887689]"
/experiment="EXISTENCE:genetic interaction:GO:0030234
enzyme regulator activity [PMID:8887689]"
/experiment="EXISTENCE:genetic interaction:GO:1903833
positive regulation of cellular response to amino acid
starvation [PMID:6351059]"
/experiment="EXISTENCE:mutant phenotype:GO:0003743
translation initiation factor activity
[PMID:8099443|PMID:34223816]"
/experiment="EXISTENCE:mutant phenotype:GO:0005851
eukaryotic translation initiation factor 2B complex
[PMID:8099443]"
/experiment="EXISTENCE:mutant phenotype:GO:0006446
regulation of translational initiation
[PMID:8099443|PMID:9032257]"
/experiment="EXISTENCE:mutant phenotype:GO:0030234 enzyme
regulator activity
[PMID:8099443|PMID:8887689|PMID:9032257]"
/experiment="EXISTENCE:mutant phenotype:GO:0045948
positive regulation of translational initiation
[PMID:34223816]"
/experiment="EXISTENCE:mutant phenotype:GO:1900036
positive regulation of cellular response to heat
[PMID:34223816]"
/experiment="EXISTENCE:mutant phenotype:GO:1903833
positive regulation of cellular response to amino acid
starvation [PMID:6351059]"
/experiment="EXISTENCE:physical interaction:GO:0005851
eukaryotic translation initiation factor 2B complex
[PMID:8506384]"
/experiment="EXISTENCE:physical interaction:GO:0006446
regulation of translational initiation [PMID:8887689]"
/note="Alpha subunit of translation initiation factor
eIF2B (eIF2Balpha); guanine-nucleotide exchange factor for
eIF2; mutations in eIF2Balpha alter localization of eIF2B;
activity regulated by phosphorylated eIF2; positive
regulator of GCN4 expression; mutations in human ortholog
EIF2B2 cause fatal brain disease childhood ataxia with
central nervous system hypomyelination (CACH); human
ortholog EIF2B1 can complement yeast null mutant"
/codon_start=1
/product="translation initiation factor eIF2B subunit
alpha"
/protein_id="DAA09181.1"
/db_xref="SGD:S000001734"
/translation="MSEFNITETYLRFLEEDTEMTMPIAAIEALVTLLRIKTPETAAE
MINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLRNLHLYGDWENCKQHLIENGQLFV
SRAKKSRNKIAEIGVDFIADDDIILVHGYSRAVFSLLNHAANKFIRFRCVVTESRPSK
QGNQLYTLLEQKGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGGIINLVGTYSVGV
LAHNARKPFYVVTESHKFVRMFPLSSDDLPMAGPPLDFTRRTDDLEDALRGPTIDYTA
QEYITALITDLGVLTPSAVSEELIKMWYD"
repeat_region complement(490286..490416)
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007059"
repeat_region 490464..490787
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007062"
gene 490968..491040
/locus_tag="YNCK0017W"
tRNA 490968..491040
/locus_tag="YNCK0017W"
/product="tRNA-Arg"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
analysis; one of 6 nuclear tRNA genes containing the
tDNA-anticodon ACG (converted to ICG in the mature tRNA),
decodes CGU, CGC, and probably CGA codons into arginine,
one of 19 nuclear tRNAs for arginine"
/db_xref="SGD:S000006703"
gene 491364..493661
/gene="BCH2"
/locus_tag="YKR027W"
/gene_synonym="FMP50"
mRNA 491364..493661
/gene="BCH2"
/locus_tag="YKR027W"
/gene_synonym="FMP50"
/product="Bch2p"
CDS 491364..493661
/gene="BCH2"
/locus_tag="YKR027W"
/gene_synonym="FMP50"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0030136
clathrin-coated vesicle [PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0030140 trans-Golgi
network transport vesicle [PMID:16498409]"
/experiment="EXISTENCE:direct assay:GO:0034044 exomer
complex [PMID:17000877]"
/experiment="EXISTENCE:genetic interaction:GO:0006893
Golgi to plasma membrane transport [PMID:16498409]"
/experiment="EXISTENCE:physical interaction:GO:0034221
fungal-type cell wall chitin biosynthetic process
[PMID:16498409]"
/note="Member of the ChAPs (Chs5p-Arf1p-binding proteins)
family; part of the exomer complex with Chs5p to mediate
export of specific cargo proteins, including Chs3p, from
the Golgi to the plasma membrane; BCH2 has a paralog,
CHS6, that arose from the whole genome duplication"
/codon_start=1
/product="Bch2p"
/protein_id="DAA09182.1"
/db_xref="SGD:S000001735"
/translation="MSFLWGSTKSKKGKNKKAAGSLPSGVVPQQRVKPTRKNVPIDYP
RTLEKVHGESLIFRTSLLSELVSTGKSGIGPPDLIHCTELDKFHDEKIGEFFYITGID
ASSVSMPIAFLKLIKWNDGKKLKSASLKNDDITTYCTFNIFQKLDIRLRYESEDVYQV
NIVDCLNGNNEIPLSDLIWEETFVSCCIRSVIINSDFERKIPGLVELPFVFENRCASD
YKRVIDSLCKFLPRFLECGWDSTKSVYATILNNYLTESLLVFLSITPEFITDYAIQVL
DNLMTNDPSNSRYYAIVIISIMERSNDRDVEMIKRIHEILDLLLPVLYGLPSDEPYIS
DLINCITDVLSIQARFLLNNNDYELSLSISTLATNLSSDNFESWYLLSKGYIFSQQYD
KALLSINSMPCLAEYDIVKQAQINAFKFYMNYYKAPLCHSREHCTMTSHELNHLMNIM
HYENELELKTIIFGRTVMPNESKYGCIEEIWNKSCLELGPICGPQSDNLINFVSQQEV
NTVGDMLLLKRSKETRQESWFIKQVRLLLMELVARIGWNALLQLRSDVFVMESKFKMI
ESSDKLSTELRQKRLCQRWFDAMFLDVYEDLSISTSSQENKATAKYSGLEWELLGLTL
LRVSDLPDAVACLRTSILARFDPISCHHLLNFYLTMDFNDEFMRRFDVDIILDLLVKL
ISFRIRFYDRFQIFSLQVLRKLEGQLGSEIIKNKIINSPYGQAGITSVIDYMLECLSK
NRNEACLAYERPLPDLPSTIKPLAD"
gene 494257..497358
/gene="SAP190"
/locus_tag="YKR028W"
mRNA 494257..497358
/gene="SAP190"
/locus_tag="YKR028W"
/product="Sap190p"
CDS 494257..497358
/gene="SAP190"
/locus_tag="YKR028W"
/experiment="EXISTENCE:genetic interaction:GO:0002098 tRNA
wobble uridine modification [PMID:18755837]"
/experiment="EXISTENCE:mutant phenotype:GO:0000082 G1/S
transition of mitotic cell cycle [PMID:8649382]"
/experiment="EXISTENCE:mutant phenotype:GO:0031929 TOR
signaling [PMID:15367655]"
/note="Protein that forms a complex with the Sit4p protein
phosphatase; required for Sit4p function; member of a
family of similar proteins including Sap4p, Sap155p, and
Sap185p; SAP190 has a paralog, SAP185, that arose from the
whole genome duplication"
/codon_start=1
/product="Sap190p"
/protein_id="DAA09183.2"
/db_xref="SGD:S000001736"
/translation="MSGSFWKFGQDYSIESPVSKILNSAFIKINKDQDDDVPTGTCEE
NIADDEDNSSHDYAASEDNVVNENEEKEEENTLPTTESEYENYRPNLDVLDDLLDDDE
LYTELMCSNFKLLIFLKYPDVLSKLIEYVTNEKILDEETDSAKKPEIIEGVNDHPILI
ERDRKDKKEDAEEGGDSEETTNDSDHDSGDERSVDSEETSITLPPESEEQVETRRARI
AAEILSADVWPISAAIMQNKDLLGRLWSILDHPAPLPIPASTYFMKINERLLDMDITG
MLEFILSRDSLVARFLTHVDNPSLMDFLLKVISTDKPDSPTGVIKILKSQELIPKLLD
HLNPEYGISTQSAAGDFIKAFVTLSTNSSNELASGIGPNELTRQLVSEEMIEKLIKIM
LKGGTSLSNGVGIIIELIRKNNSDYDFIQLVYTTLESHPPTDRDPIHLIHLVKLFAKH
MPDFADMLDKTKLPLMEMPFGNIEPLGFERFKICELIAELLHCSNMTLLNEPNGEMIA
QERDIERAKELETSTEKENITAIVDNKSSYYDKDCVEKDITENLGALQINNQGSEEDE
LNDTGVSSVKLDVKSDAKVVEGLENDASGVELYDETLSDTESVRECLREKPLVGDRLK
IALEDTKILISILDMFTEFPWNNFLHNVIFDIAQQIFNGPLKTGYNRFLLKDYLVDAY
LTKKIVDADKACQDYEKKTGLRYGYMGHLTLVAEEISKFKEYIDEMKLTFCNTAVSDR
LEEPFWKEYSETILADTREKYNTVLGDFGNDQESDDDVIRNSDSEDIIGDTEGNENYG
NGENDELLSNGHDSGNMDLYYNFNNNENEENEEDYAEYSDVDNKNYYNNVETNDDDYD
SDDGKSKSAESEFTDKISEHRDGNSLYNEDNDENGSDKWTSGTSLFPPDHFPSRSQPS
DPKLQDQNIFHHQFDFEGVGDDDDYMDPNDDGQSYARPGNPLYTTPKTPPRPKTILFN
SLSALDNNGEDEEVALGTSVDDRMDNEISSDEEDSEDEDEENDMGNEEGYSLYRSRSK
EAF"
gene complement(497578..499833)
/gene="SET3"
/locus_tag="YKR029C"
mRNA complement(497578..499833)
/gene="SET3"
/locus_tag="YKR029C"
/product="histone-binding protein SET3"
CDS complement(497578..499833)
/gene="SET3"
/locus_tag="YKR029C"
/experiment="EXISTENCE:direct assay:GO:0034967 Set3
complex [PMID:11711434]"
/experiment="EXISTENCE:direct assay:GO:0035064 methylated
histone binding [PMID:17142463]"
/experiment="EXISTENCE:direct assay:GO:0070210
Rpd3L-Expanded complex [PMID:19040720]"
/experiment="EXISTENCE:mutant phenotype:GO:0006355
regulation of DNA-templated transcription [PMID:19379692]"
/experiment="EXISTENCE:mutant phenotype:GO:0006479 protein
methylation [PMID:31960028]"
/experiment="EXISTENCE:mutant phenotype:GO:0045835
negative regulation of meiotic nuclear division
[PMID:11711434]"
/note="Defining member of the SET3 histone deacetylase
complex; which is a meiosis-specific repressor of
sporulation genes; necessary for efficient transcription
by RNAPII; one of two yeast proteins that contains both
SET and PHD domains; SET3 has a paralog, SET4, that arose
from the whole genome duplication"
/codon_start=1
/product="histone-binding protein SET3"
/protein_id="DAA09184.1"
/db_xref="SGD:S000001737"
/translation="MSVPNSKEQSLLDDASTLLLFSKGKKRAEEASKIGSKTDTIEHD
ESHEREKKGAIEMAAAALATASTVSLPLKKATEQSAAEAATSTAAKEETENQPQKQPQ
WPVPDSYIVDPDAGIITCICDLNDDDGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLC
NSCDPREVDINLARKIQQERINVKTVEPSSSNNSASNKNNGRDRASSTTISDVGDSFS
TDQDNTNHRDKRRKRNPSNNSIDSKNESASVNSSDGLTSMPKKKEHFLSAKDAYGAIY
LPLKDNVFKSDLIEPFLNKHMDDNWVIQYPHKTFKSVSIEVKPYADIAYSRTYPGFTK
LGVYLKKDCIKGDFIQEILGELDFYKNYLTDPRNHYRIWGTAKRRVIFHSHWPIYIDA
RLSGNSTRYLRRSCQPNVELVTIKLQDTDNRNDKSSGRKSSRIKFVLRALRDISEDEE
LYIKWQWDSKHPILKLIKGMTIDSLDDLERYGLINSVETILSNGECGCGNNSKDCYLL
KVKRYAQSLYKSVKSRGKMNNRYKLNEILNQYNCKKRREPPILHRLEEKAQNTIERAP
ILLNNFYRQKFLNRNNGPKIPQKNTIDSTNNPDDIAKPFKFALFAQHSSNISVPKKNE
TSEKPLIITKSTDYDESHITNIEELPIPVLLPINKTSRQTANDVEESQSKNEHKLSRT
PSLSNFNKELSKEAQHSQAKTKEIMTEASVNSRRESTPESIMHLSDFSSSQLHSKKKL
SFADYRKKLLK"
gene 500282..501103
/gene="GMH1"
/locus_tag="YKR030W"
/gene_synonym="MSG1"
mRNA 500282..501103
/gene="GMH1"
/locus_tag="YKR030W"
/gene_synonym="MSG1"
/product="Gmh1p"
CDS 500282..501103
/gene="GMH1"
/locus_tag="YKR030W"
/gene_synonym="MSG1"
/experiment="EXISTENCE:direct assay:GO:0000139 Golgi
membrane [PMID:12808035]"
/experiment="EXISTENCE:physical interaction:GO:0016192
vesicle-mediated transport [PMID:12808035]"
/note="Golgi membrane hypothetical protein; interacts with
Gea1p and Gea2p; required for localization of Gea2p;
computational analysis suggests a possible role in either
cell wall synthesis or protein-vacuolar targeting;
conserved from yeast to human"
/codon_start=1
/product="Gmh1p"
/protein_id="DAA09185.1"
/db_xref="SGD:S000001738"
/translation="MSYLPTYSNDLPAGPQGQRRRNNGNENDARQGYGQQSVPMVIRR
LFKTPKNLDLETASWEMFHLIFHPRKAYRSIYYQRQTKNQWARDDPSFFIFQIALISL
SSIIWSIYNSGFNNDSDMGALSIIGHFFKSLVMMVILDFFIFGFIMATIFYLLLNRSH
FKFKSSQNSVVEWAYCFDVHCNSFLIILLCLYFIQFLLLPIINLQNWISLLIGNSLYC
FAIGHYFILTFYGYNQLPFLKNLNFILLPTLGLSIIYLISLFGIDLSKKLSFYNY"
gene complement(501344..506395)
/gene="SPO14"
/locus_tag="YKR031C"
/gene_synonym="PLD1"
mRNA complement(501344..506395)
/gene="SPO14"
/locus_tag="YKR031C"
/gene_synonym="PLD1"
/product="phospholipase D"
CDS complement(501344..506395)
/gene="SPO14"
/locus_tag="YKR031C"
/gene_synonym="PLD1"
/EC_number="3.1.4.4"
/experiment="EXISTENCE:direct assay:GO:0004630
phospholipase D activity [PMID:11514437]"
/experiment="EXISTENCE:direct assay:GO:0005628 prospore
membrane [PMID:9693364]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:21954159]"
/experiment="EXISTENCE:direct assay:GO:0005768 endosome
[PMID:10848624]"
/experiment="EXISTENCE:direct assay:GO:0006644
phospholipid metabolic process [PMID:8576189]"
/experiment="EXISTENCE:direct assay:GO:0032266
phosphatidylinositol-3-phosphate binding [PMID:11557775]"
/experiment="EXISTENCE:genetic interaction:GO:0000753 cell
morphogenesis involved in conjugation with cellular fusion
[PMID:18036176]"
/experiment="EXISTENCE:mutant phenotype:GO:0000753 cell
morphogenesis involved in conjugation with cellular fusion
[PMID:12702348]"
/experiment="EXISTENCE:mutant phenotype:GO:0006644
phospholipid metabolic process [PMID:8576189]"
/experiment="EXISTENCE:mutant phenotype:GO:0031321
ascospore-type prospore assembly [PMID:16554438]"
/note="Phospholipase D; catalyzes the hydrolysis of
phosphatidylcholine, producing choline and phosphatidic
acid; involved in Sec14p-independent secretion; required
for meiosis and spore formation; differently regulated in
secretion and meiosis; participates in transcription
initiation and/or early elongation of specific genes;
interacts with 'foot domain' of RNA polymerase II;
deletion results in abnormal CTD-Ser5 phosphorylation of
RNA polymerase II at specific promoter regions"
/codon_start=1
/product="phospholipase D"
/protein_id="DAA09186.1"
/db_xref="SGD:S000001739"
/translation="MSNVSTASGTHFAPPQADRSVTEEVDRVNSRPDELENQEVLRQL
PENGNLTSSLQREKRRTPNGKEAERKHALPKSFVDRNLSDVSPNHSLDHIMHSNEHDP
RRGSDEENMHRLYNNLHSSNNNVHSKRNSKREEERAPQRRSSSVAYTQQQFNGWKKEF
GHAFKKISAIGRLKSSVNSPTPAGSGHRHNQHQHQQVNEEDLYTQRLASDLLDSLLAG
CPASLFASTQFLRDEHGKRRAPLLLAKLDVRVSPLKNDNNILDITNSNHNHRGNNNNN
TGENSDRRPSIPRSSSIISISSNVAEFMYSRNENSLFRIHLEYGIDEDRLKWSIIRSY
KDIKSLHHKLKIVAFQQLTISKLYSDNNRYHSLQLPHFPHYKEMVKERNVMEKKAENK
PSSAASAPHTSENNNNDNGSNITSLETLSSSEISEFNIDNVKMKHLQDLIDEPDDFSQ
PIHLRLERYLRLLNIALCLRPHANRLFEFYELSPLGNLLSRESGFQGKQGYLVIRSTA
KAQGWRVSHFGKHAFKDMIDRHTTKWFLVRNSYLTYVSDLSSTTPLDVFLIDWKFKVR
FSGNKNNILDNENEINWIIHDPNLEINDELEEFGIENDANNILDKNGKSKTHQKKSNI
SSKLLLLTLENSERKLKIICKSESSLKQWMSSIIKMSTSTPWSKPNRFGSFAPVRTNS
FCKFLVDGRDYFWSLSEALLMAKDVIYIHDWWLSPELYLRRPVKGNQGFRIDRMLKSC
AEKGIKIFIVIYRNVGNIVGTDSLWTKHSMLNLHPNIHIIRSPNQWLQNTYFWAHHEK
FVVIDETFAFIGGTDLCYGRYDTFEHVLRDDAESLLDQNFPGKDYSNARIADFHDLDK
PFESMYDRKVIPRMPWHDVQMMTLGEPARDLARHFVQRWNYLLRAKRPSRLTPLLTPP
SDLTAEELKSLPMFEILREKSTCETQILRSAGNWSLGLKETECSIQNAYLKLIEQSEH
FIYIENQFFITSTVWNGTCVLNKIGDALVDRIVKANQEKKPWKAFILIPLMPGFDSPV
DTAEASSLRLIMQFQYQSISRGEHSTFSKLKKLNIDPAQYIQFFSLRKWSTFAPNERL
ITEQLYVHAKILIADDRRCIIGSANINERSQLGNRDSEVAILIRDTDLIKTKMNGDDY
YAGKFPWELRQRLMREHLGCDVDLVEFVEKKFERFEKFAAKNYEKLHTLSKEGDSGNN
WSDREMIDSAMIELGYREIFGCKFSPQWKSGHGNSVDDGSTQCGINEKEVGREDENVY
EKFFNSVDYGKSSRKRTPLPKHNFASLGLTFNHRAGIENVGIRDHKVLSTDPRLRKND
EHKKEVDGYGPDCWKKESNKKFKADATEQLKEWALNSLASKVLDDKEMIKSEIPEGFS
NYLPNEKDLEMYLTDKTVTNRNKWSMLKRICYLQYLSHKLDERKTQRLKKIKDMRRHL
SSSTESTRNGSNSLPLNEKSNEGESTNVDQDIEGDEYHRLHEDILKNQELDDGSLDDL
LSQIIPKITNFNSGEIDDAKKEELLKLNFIDPYSFEDPLISSFSEGLWFTIALRNTLL
YKLVFHCQPDNAVQNWKEYGEFTELEQEFQINQEKLIDLEAENINSTTTNVVDKDREK
EKMRKAAELRMKLSGSLLYGFNQKVFDKHTAQRILERIHGHLVIFPTEWLAKEVESRN
WIFNSDRLSPMEIYN"
gene 506517..506831
/locus_tag="YKR032W"
mRNA 506517..506831
/locus_tag="YKR032W"
/product="hypothetical protein"
CDS 506517..506831
/locus_tag="YKR032W"
/note="hypothetical protein; conserved among S. cerevisiae
strains"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA80311.1"
/db_xref="SGD:S000001740"
/translation="MAYSSLCLCLLFNPKGCSNLHPFVVDNEFPPYHLSLVLIKQQRM
LDRNRSWAYLAALWRHPWTVISKCCLVYIYIQRQLEFGYSYCFFDFLLVILSETVVIL
YY"
gene 506898..507707
/gene="DAL80"
/locus_tag="YKR034W"
/gene_synonym="UGA43"
mRNA 506898..507707
/gene="DAL80"
/locus_tag="YKR034W"
/gene_synonym="UGA43"
/product="Dal80p"
CDS 506898..507707
/gene="DAL80"
/locus_tag="YKR034W"
/gene_synonym="UGA43"
/experiment="EXISTENCE:direct assay:GO:0000981 DNA-binding
transcription factor activity, RNA polymerase II-specific
[PMID:8045902]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:11443099]"
/experiment="EXISTENCE:direct assay:GO:0043565
sequence-specific DNA binding [PMID:8376332]"
/experiment="EXISTENCE:mutant phenotype:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:7899075|PMID:8045902|PMID:8416910]"
/experiment="EXISTENCE:mutant phenotype:GO:0090295
nitrogen catabolite repression of transcription
[PMID:1944286|PMID:6757722|PMID:7899075]"
/note="Negative regulator of genes in multiple nitrogen
degradation pathways; expression is regulated by nitrogen
levels and by Gln3p; member of the GATA-binding family,
forms homodimers and heterodimers with Gzf3p; DAL80 has a
paralog, GZF3, that arose from the whole genome
duplication"
/codon_start=1
/product="Dal80p"
/protein_id="DAA09187.1"
/db_xref="SGD:S000001742"
/translation="MVLSDSLKLPSPTLSAAAGVDDCDGEDHPTCQNCFTVKTPLWRR
DEHGTVLCNACGLFLKLHGEPRPISLKTDTIKSRNRKKLNNNNVNTNANTHSNDPNKI
FKRKKRLLTTGGGSLPTNNPKVSILEKFMVSGSIKPLLKPKETVPNTKECSTQRGKFS
LDPCEPSGKNYLYQINGSDIYTSNIELTRLPNLSTLLEPSPFSDSAVPEIELTWKLHN
EEEVIKLKTKISELELVTDLYKKHIFQLNEKCKQLEVELHSRASVQSHPQH"
gene 507939..508553
/gene="DID2"
/locus_tag="YKR035W-A"
/gene_synonym="CHM1"
/gene_synonym="FTI1"
/gene_synonym="VPL30"
/gene_synonym="VPS46"
mRNA 507939..508553
/gene="DID2"
/locus_tag="YKR035W-A"
/gene_synonym="CHM1"
/gene_synonym="FTI1"
/gene_synonym="VPL30"
/gene_synonym="VPS46"
/product="Did2p"
CDS 507939..508553
/gene="DID2"
/locus_tag="YKR035W-A"
/gene_synonym="CHM1"
/gene_synonym="FTI1"
/gene_synonym="VPL30"
/gene_synonym="VPS46"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11029042]"
/experiment="EXISTENCE:direct assay:GO:0005770 late
endosome [PMID:11029042]"
/experiment="EXISTENCE:direct assay:GO:1904902 ESCRT III
complex assembly [PMID:31273031]"
/experiment="EXISTENCE:mutant phenotype:GO:0006623 protein
targeting to vacuole [PMID:11029042]"
/experiment="EXISTENCE:mutant phenotype:GO:0032511 late
endosome to vacuole transport via multivesicular body
sorting pathway [PMID:17130288]"
/experiment="EXISTENCE:mutant phenotype:GO:0045324 late
endosome to vacuole transport [PMID:12194857]"
/note="Class E protein of the vacuolar protein-sorting
(Vps) pathway; binds Vps4p and directs it to dissociate
ESCRT-III complexes; forms a functional and physical
complex with Ist1p; human ortholog may be altered in
breast tumors"
/codon_start=1
/product="Did2p"
/protein_id="DAA09188.1"
/db_xref="SGD:S000006435"
/translation="MSRNSAAGLENTLFQLKFTSKQLQKQANKASKEEKQETNKLKRA
LNENEDISRIYASNAIRKKNERLQLLKLASRVDSVASRVQTAVTMRQVSASMGQVCKG
MDKALQNMNLQQITMIMDKFEQQFEDLDTSVNVYEDMGVNSDAMLVDNDKVDELMSKV
ADENGMELKQSAKLDNVPEIKAKEVNVDDEKEDKLAQRLRALRG"
gene complement(508702..510633)
/gene="CAF4"
/locus_tag="YKR036C"
mRNA complement(508702..510633)
/gene="CAF4"
/locus_tag="YKR036C"
/product="Caf4p"
CDS complement(508702..510633)
/gene="CAF4"
/locus_tag="YKR036C"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion
[PMID:14576278|PMID:16009724|PMID:16823961|PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0030014 CCR4-NOT
complex [PMID:11113136]"
/experiment="EXISTENCE:genetic interaction:GO:0016559
peroxisome fission [PMID:18445678]"
/experiment="EXISTENCE:mutant phenotype:GO:0000266
mitochondrial fission [PMID:16009724]"
/experiment="EXISTENCE:mutant phenotype:GO:0006357
regulation of transcription by RNA polymerase II
[PMID:11113136]"
/experiment="EXISTENCE:physical interaction:GO:0000266
mitochondrial fission [PMID:16009724]"
/experiment="EXISTENCE:physical interaction:GO:0006357
regulation of transcription by RNA polymerase II
[PMID:11113136]"
/note="WD40 repeat-containing protein associated with the
CCR4-NOT complex; interacts in a Ccr4p-dependent manner
with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and
plays a role in mitochondrial fission; CAF4 has a paralog,
MDV1, that arose from the whole genome duplication"
/codon_start=1
/product="Caf4p"
/protein_id="DAA09189.2"
/db_xref="SGD:S000001744"
/translation="MGSGDTRGESSLVAKPIEIILNKLPHAILAQQQFQKYITSPIYR
YLSKLLLFREVAWPESTKDTQKGQVGIFSFQNNYADSATTFRILAHLDEQRYPLPNGA
AEKNLPSLFEGFKATVSIIQQRLLLDNVDGATNSDKEKYVQLPDINTGFVNKTYSRID
LTHLLEDVETNVENLSINKTLEMDELTRLDSMINELESRKLKILERVKHIDSKSTNLE
NDVTLIKDRINFIEEYNLEADREQSLRKQMEEERSSEASSFTQNEEAISSLCDVESKD
TRLKDFYKMPHEKSHDKNRQIISETYSRNTTAFRMTIPHGEHGNSITALDFDTPWGTL
CSSSYQDRIVKVWDLNHGIQVGELPGHLATVNCMQIDKKNYNMLITGSKDATLKLWDL
NLSREIYLDHSPLKEKTEEIVTPCIHNFELHKDEITALSFDSEALVSGSRDKKIFHWD
LTTGKCIQQLDLIFTPTHSDIKMPARSLNNGACLLGTEAPMIGALQCYNSALATGTKD
GIVRLWDLRVGKPVRLLEGHTDGITSLKFDSEKLVTGSMDNSVRIWDLRTSSILDVIA
YDLPVSSLDFDGKLITVGANEGGVNVFNMERDEHWMTPEPPHSLDGDELSRRIAIVKY
KDGFLINGHNDGDINVWTL"
gene complement(510910..511797)
/gene="SPC34"
/locus_tag="YKR037C"
mRNA complement(510910..511797)
/gene="SPC34"
/locus_tag="YKR037C"
/product="Spc34p"
CDS complement(510910..511797)
/gene="SPC34"
/locus_tag="YKR037C"
/experiment="EXISTENCE:direct assay:GO:0008017 microtubule
binding [PMID:15664196|PMID:16777964]"
/experiment="EXISTENCE:direct assay:GO:0008608 attachment
of spindle microtubules to kinetochore [PMID:17620411]"
/experiment="EXISTENCE:direct assay:GO:0031116 positive
regulation of microtubule polymerization [PMID:15664196]"
/experiment="EXISTENCE:direct assay:GO:0042729 DASH
complex [PMID:15640796|PMID:15664196]"
/experiment="EXISTENCE:direct assay:GO:0051010 microtubule
plus-end binding [PMID:17620411|PMID:20479465]"
/experiment="EXISTENCE:direct assay:GO:0051987 positive
regulation of attachment of spindle microtubules to
kinetochore [PMID:20479465|PMID:20479468]"
/note="Essential subunit of the Dam1 complex (aka DASH
complex); complex couples kinetochores to the force
produced by MT depolymerization thereby aiding in
chromosome segregation; also localized to nuclear side of
spindle pole body"
/codon_start=1
/product="Spc34p"
/protein_id="DAA09190.1"
/db_xref="SGD:S000001745"
/translation="MGESLDRCIDDINRAVDSMSTLYFKPPGIFHNAILQGASNKASI
RKDITRLIKDCNHDEAYLLFKVNPEKQSVSRRDGKEGVFDYVIKRDTDMKRNRRLGRP
GEKPIIHVPKEVYLNKDRLDLNNKRRRTATTSGGGLNGFIFDTDLIGSSVISNSSSGT
FKALSAVFKDDPQIQRLLYALENGSVLMEEESNNQRRKTIFVEDFPTDLILKVMAEVT
DLWPLTEFKQDYDQLYHNYEQLSSKLRFIKKEVLLQDDRLKTMSQYHPSSSHDVAKII
RKEKDEIRRLEMEIANLQE"
gene complement(511999..513159)
/gene="KAE1"
/locus_tag="YKR038C"
mRNA complement(511999..513159)
/gene="KAE1"
/locus_tag="YKR038C"
/product="tRNA N6-adenosine threonylcarbamoyltransferase"
CDS complement(511999..513159)
/gene="KAE1"
/locus_tag="YKR038C"
/EC_number="2.3.1.234"
/experiment="EXISTENCE:direct assay:GO:0000408 EKC/KEOPS
complex [PMID:16564010|PMID:16874308]"
/experiment="EXISTENCE:direct assay:GO:0000785 chromatin
[PMID:16874308]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0006400 tRNA
modification [PMID:23620299]"
/experiment="EXISTENCE:direct assay:GO:0008252
nucleotidase activity [PMID:36416748]"
/experiment="EXISTENCE:direct assay:GO:0031490 chromatin
DNA binding [PMID:16874308]"
/experiment="EXISTENCE:genetic interaction:GO:0000722
telomere maintenance via recombination [PMID:23390378]"
/experiment="EXISTENCE:mutant phenotype:GO:0000722
telomere maintenance via recombination [PMID:23390378]"
/experiment="EXISTENCE:mutant phenotype:GO:0000723
telomere maintenance [PMID:36416748]"
/experiment="EXISTENCE:mutant phenotype:GO:0008252
nucleotidase activity [PMID:36416748]"
/experiment="EXISTENCE:mutant phenotype:GO:0051276
chromosome organization [PMID:18439903]"
/experiment="EXISTENCE:mutant phenotype:GO:0070525 tRNA
threonylcarbamoyladenosine metabolic process
[PMID:21459853|PMID:21183954]"
/experiment="EXISTENCE:physical interaction:GO:0000723
telomere maintenance [PMID:16564010]"
/experiment="EXISTENCE:physical interaction:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:16874308]"
/note="ADP/GDP nucleotidase, essential functional
component of KEOPS complex, with Bud32p, Cgi121p, Pcc1p,
and Gon7p; EKC/KEOPS complex is required for t6A tRNA
modification and telomeric TG1-3 recombination; may have
role in transcription; homolog of human OSGEP"
/codon_start=1
/product="tRNA N6-adenosine threonylcarbamoyltransferase"
/protein_id="DAA09191.1"
/db_xref="SGD:S000001746"
/translation="MVNLNTIPPKNGRDYYIALGLEGSANKLGVGIVKHPLLPKHANS
DLSYDCEAEMLSNIRDTYVTPPGEGFLPRDTARHHRNWCIRLIKQALAEADIKSPTLD
IDVICFTKGPGMGAPLHSVVIAARTCSLLWDVPLVGVNHCIGHIEMGREITKAQNPVV
LYVSGGNTQVIAYSEKRYRIFGETLDIAIGNCLDRFARTLKIPNEPSPGYNIEQLAKK
APHKENLVELPYTVKGMDLSMSGILASIDLLAKDLFKGNKKNKILFDKTTGEQKVTVE
DLCYSLQENLFAMLVEITERAMAHVNSNQVLIVGGVGCNVRLQEMMAQMCKDRANGQV
HATDNRFCIDNGVMIAQAGLLEYRMGGIVKDFSETVVTQKFRTDEVYAAWRD"
gene complement(513332..513403)
/locus_tag="YNCK0018C"
tRNA complement(513332..513403)
/locus_tag="YNCK0018C"
/product="tRNA-Asp"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE
analysis"
/db_xref="SGD:S000006540"
repeat_region complement(513532..513846)
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007060"
gene 515063..516871
/gene="GAP1"
/locus_tag="YKR039W"
mRNA 515063..516871
/gene="GAP1"
/locus_tag="YKR039W"
/product="amino acid permease GAP1"
CDS 515063..516871
/gene="GAP1"
/locus_tag="YKR039W"
/experiment="EXISTENCE:direct assay:GO:0000328 fungal-type
vacuole lumen [PMID:15039776]"
/experiment="EXISTENCE:direct assay:GO:0005768 endosome
[PMID:15039776]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:15623581|PMID:15707981|PMID:9199164]"
/experiment="EXISTENCE:direct assay:GO:0030134
COPII-coated ER to Golgi transport vesicle
[PMID:12499351]"
/experiment="EXISTENCE:genetic interaction:GO:0015193
L-proline transmembrane transporter activity
[PMID:14968425]"
/experiment="EXISTENCE:mutant phenotype:GO:0001761
beta-alanine transmembrane transporter activity
[PMID:29570051]"
/experiment="EXISTENCE:mutant phenotype:GO:0005771
multivesicular body [PMID:14523026]"
/experiment="EXISTENCE:mutant phenotype:GO:0006865 amino
acid transport [PMID:6759873]"
/experiment="EXISTENCE:mutant phenotype:GO:0015171 amino
acid transmembrane transporter activity [PMID:6759873]"
/experiment="EXISTENCE:mutant phenotype:GO:0015203
polyamine transmembrane transporter activity
[PMID:15707981]"
/experiment="EXISTENCE:mutant phenotype:GO:0015846
polyamine transport [PMID:15707981]"
/note="General amino acid permease; involved in uptake of
all L-amino acids, some D-amino acids, related compounds,
toxic analogs and polyamines; regulated by nitrogen
source; targeted to vacuole via Vps10p-dependent endosomal
vacuolar protein sorting pathway; essential for invasive
growth"
/codon_start=1
/product="amino acid permease GAP1"
/protein_id="DAA09192.1"
/db_xref="SGD:S000001747"
/translation="MSNTSSYEKNNPDNLKHNGITIDSEFLTQEPITIPSNGSAVSID
ETGSGSKWQDFKDSFKRVKPIEVDPNLSEAEKVAIITAQTPLKHHLKNRHLQMIAIGG
AIGTGLLVGSGTALRTGGPASLLIGWGSTGTMIYAMVMALGELAVIFPISGGFTTYAT
RFIDESFGYANNFNYMLQWLVVLPLEIVSASITVNFWGTDPKYRDGFVALFWLAIVII
NMFGVKGYGEAEFVFSFIKVITVVGFIILGIILNCGGGPTGGYIGGKYWHDPGAFAGD
TPGAKFKGVCSVFVTAAFSFAGSELVGLAASESVEPRKSVPKAAKQVFWRITLFYILS
LLMIGLLVPYNDKSLIGASSVDAAASPFVIAIKTHGIKGLPSVVNVVILIAVLSVGNS
AIYACSRTMVALAEQRFLPEIFSYVDRKGRPLVGIAVTSAFGLIAFVAASKKEGEVFN
WLLALSGLSSLFTWGGICICHIRFRKALAAQGRGLDELSFKSPTGVWGSYWGLFMVII
MFIAQFYVAVFPVGDSPSAEGFFEAYLSFPLVMVMYIGHKIYKRNWKLFIPAEKMDID
TGRREVDLDLLKQEIAEEKAIMATKPRWYRIWNFWC"
rep_origin 517017..517265
/note="ARS1116; Autonomously Replicating Sequence"
/db_xref="SGD:S000118407"
repeat_region complement(517453..517784)
/note="Ty1 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007061"
gene 517988..518060
/locus_tag="YNCK0019W"
tRNA 517988..518060
/locus_tag="YNCK0019W"
/product="tRNA-Ala"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
analysis; one of 11 nuclear tRNA genes containing the
tDNA-anticodon AGC (converted to IGC in the mature tRNA),
decodes GCU and GCC codons into alanine, one of 16 nuclear
tRNAs for alanine"
/db_xref="SGD:S000006516"
gene 518198..518950
/locus_tag="YKR041W"
mRNA 518198..518950
/locus_tag="YKR041W"
/product="hypothetical protein"
CDS 518198..518950
/locus_tag="YKR041W"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095|PMID:21777356]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0072686 mitotic
spindle [PMID:21777356]"
/note="hypothetical protein; localizes to the mitotic
spindle; overexpression of YKR041W affects endocytic
protein trafficking"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09193.1"
/db_xref="SGD:S000001749"
/translation="MSDDDYMNSDDDNDAEKRYVRPIFVRKRRREEDYVATSKDNIHH
HPCDWSAKPSQRQNENEQKSTIRLVPVAMNTPKCQEKKKKRKGVGTTSHEATLFEYGE
SIAGYKCVTTESERDRLKRSHESESSSESEVDVFAFDQAKGISSKVEAEERYARAVRQ
YWRMTKDEPATLPLPGTPTLAAVSLDMIDDKSVEQFYTMSSALMDANRLDLIRRDRIR
WHPDKHRYHKSKVTKLFQAINGLWEQEKTEKR"
gene 519527..520624
/gene="UTH1"
/locus_tag="YKR042W"
mRNA 519527..520624
/gene="UTH1"
/locus_tag="YKR042W"
/product="SUN family protein UTH1"
CDS 519527..520624
/gene="UTH1"
/locus_tag="YKR042W"
/experiment="EXISTENCE:direct assay:GO:0005743
mitochondrial inner membrane [PMID:23910823]"
/experiment="EXISTENCE:mutant phenotype:GO:0000422
autophagy of mitochondrion [PMID:15247238]"
/experiment="EXISTENCE:mutant phenotype:GO:0009272
fungal-type cell wall biogenesis [PMID:20070376]"
/note="Mitochondrial inner membrane protein; role in
mitophagy is disputed; implicated in cell wall biogenesis,
the oxidative stress response, life span during
starvation, and cell death; SUN family member; UTH1 has a
paralog, NCA3, that arose from the whole genome
duplication"
/codon_start=1
/product="SUN family protein UTH1"
/protein_id="DAA09194.1"
/db_xref="SGD:S000001750"
/translation="MKLSALLALSASTAVLAAPAVHHSDNHHHNDKRAVVTVTQYVNA
DGAVVIPAATTATSAAADGKVESVAAATTTLSSTAAAATTSAAASSSSSSSSSSSSSS
SVGSGDFEDGTISCSDFPSGQGAVSLDWLGLGGWASIMDMNGNTATSCQDGYYCSYAC
SPGYAKTQWPSEQPSDGRSVGGLYCKNGKLYRSNTDTNSLCVEGQGSAQAVNKVSGSI
AICGTDYPGSENMVVPTVVGAGSSQPINVIKEDSYYQWQGKKTSAQYYVNNAGVSVED
GCIWGTEGSGVGNWAPVVLGAGYTDGITYLSIIPNPNNKEAPNFNIKIVATDGSTVNG
ACSYENGVYSGSGSDGCTVSVTSGSANFVFY"
gene complement(520897..521712)
/gene="SHB17"
/locus_tag="YKR043C"
mRNA complement(520897..521712)
/gene="SHB17"
/locus_tag="YKR043C"
/product="sedoheptulose-bisphosphatase"
CDS complement(520897..521712)
/gene="SHB17"
/locus_tag="YKR043C"
/EC_number="3.1.3.37"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0046390 ribose
phosphate biosynthetic process [PMID:21663798]"
/experiment="EXISTENCE:direct assay:GO:0050278
sedoheptulose-bisphosphatase activity [PMID:21663798]"
/experiment="EXISTENCE:mutant phenotype:GO:0046390 ribose
phosphate biosynthetic process [PMID:21663798]"
/experiment="EXISTENCE:mutant phenotype:GO:0050278
sedoheptulose-bisphosphatase activity [PMID:21663798]"
/note="Sedoheptulose bisphosphatase involved in
riboneogenesis; dephosphorylates sedoheptulose
1,7-bisphosphate, which is converted via the nonoxidative
pentose phosphate pathway to ribose-5-phosphate;
facilitates the conversion of glycolytic intermediates to
pentose phosphate units; also has fructose
1,6-bisphosphatase activity but this is probably not
biologically relevant, since deletion does not affect FBP
levels; GFP-fusion protein localizes to the cytoplasm and
nucleus"
/codon_start=1
/product="sedoheptulose-bisphosphatase"
/protein_id="DAA09195.1"
/db_xref="SGD:S000001751"
/translation="MPSLTPRCIIVRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTG
ESVFRNNQFLNPDNITYIFTSPRLRARQTVDLVLKPLSDEQRAKIRVVVDDDLREWEY
GDYEGMLTREIIELRKSRGLDKERPWNIWRDGCENGETTQQIGLRLSRAIARIQNLHR
KHQSEGRASDIMVFAHGHALRYFAAIWFGLGVQKKCETIEEIQNVKSYDDDTVPYVKL
ESYRHLVDNPCFLLDAGGIGVLSYAHHNIDEPALELAGPFVSPPEEESQHGDV"
gene 522015..523346
/gene="UIP5"
/locus_tag="YKR044W"
mRNA 522015..523346
/gene="UIP5"
/locus_tag="YKR044W"
/product="Uip5p"
CDS 522015..523346
/gene="UIP5"
/locus_tag="YKR044W"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005635 nuclear
envelope [PMID:11056382]"
/note="hypothetical protein that interacts with Ulp1p; a
Ubl (ubiquitin-like protein)-specific protease for Smt3p
protein conjugates"
/codon_start=1
/product="Uip5p"
/protein_id="DAA09196.1"
/db_xref="SGD:S000001752"
/translation="MSRDVRAEKLAISLLILSLFLIFQLVAEIYLNNGDQYHTETSPF
TRGRSHVTRVPNHDASLSIPFLDKINQFWHVGGATQIRNIQSIKLTQDRDQDKHGLVL
SNGIGDNTINDFEIVFTFRISHDPTTQLTGDGMCFAITPENGFLTQNLQSSYAKKQYM
MNSQGVIADNTDLMGFPKNLPGLFIVLDTYRNQGHDHKEVPFMDVFINVAPESDWYDI
NSDGELSTSLRLNSRGHIKLKKNALWNRVTKLRIIYLESISFLKIDVQYAKEGNYWIE
LFQTTENLYLPKNMHTGQRYIGCSALNGQLTETVELLDVSTSEFHWNDMDASIEDTYD
YAKEAELFLEQEFGEVLDREPDEFTKWKMIKAQPNIKTGSQSAEQKTSNNPHSRLFKV
VLTIWHYSEILLLIMGIYLFSACIRVFQRRFKKIRSRRKRAGSHSVGLLPM"
gene complement(523418..523969)
/locus_tag="YKR045C"
mRNA complement(523418..523969)
/locus_tag="YKR045C"
/product="hypothetical protein"
CDS complement(523418..523969)
/locus_tag="YKR045C"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276]"
/note="hypothetical protein; epitope-tagged protein
localizes to the cytoplasm"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09197.1"
/db_xref="SGD:S000001753"
/translation="MSNSHHTSQGRRNKLSVWVKKIINTTTTTNASVSSSKPRRGTRA
GPTRVKRAELDPDGTTISSSLRPLVDRNSLHSSESDDEGDRRVAWDEPPTGKVRQQQQ
QQQQQQNDNASVIPLVSFCSSSVKSSTFSDIHSIQSTRPTIFSNRTFETNSSVLAIPP
QSILDRSRTLPPSNASNTTTRRP"
gene complement(524223..525074)
/gene="PLN1"
/locus_tag="YKR046C"
/gene_synonym="PET10"
mRNA complement(524223..525074)
/gene="PLN1"
/locus_tag="YKR046C"
/gene_synonym="PET10"
/product="Pln1p"
CDS complement(524223..525074)
/gene="PLN1"
/locus_tag="YKR046C"
/gene_synonym="PET10"
/experiment="EXISTENCE:direct assay:GO:0005811 lipid
droplet [PMID:10515935|PMID:24868093]"
/experiment="EXISTENCE:expression pattern:GO:0009060
aerobic respiration [PMID:10618406]"
/note="Perilipin, involved in formation and stability of
lipid droplets; expression pattern suggests a role in
respiratory growth; computational analysis of large-scale
protein-protein interaction data suggests a role in
ATP/ADP exchange"
/codon_start=1
/product="Pln1p"
/protein_id="DAA09198.1"
/db_xref="SGD:S000001754"
/translation="MSESSISSSKPSVELPQATWSHLQRYPALSKFIKYAESLPPVER
LISFNLVVLGSVNQWVSESSSSPRLVKQVVAAGKEGAFKLDELVNLLVFKEGVDGLLY
NWKSHSNTPGIWLVWFFVDYVANISNTLLREFLIKPLHLQGSTASKEIGSSGEENKVT
DASSLPHVAELSSTTRGMSQEIQSKVKSNYIDPTKDLAKEKYDAIVKPTTDKLQSVYI
DPTKTKLNETYQRFTTVYENNLSKSESVPKAIVSTGLDLGNATIEKLKASREDQTNSK
PAAVSTN"
gene complement(525387..526640)
/gene="NAP1"
/locus_tag="YKR048C"
mRNA complement(525387..526640)
/gene="NAP1"
/locus_tag="YKR048C"
/product="histone chaperone NAP1"
CDS complement(525387..526640)
/gene="NAP1"
/locus_tag="YKR048C"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:30341817|PMID:7622566]"
/experiment="EXISTENCE:direct assay:GO:0006334 nucleosome
assembly [PMID:1400414|PMID:2016313]"
/experiment="EXISTENCE:direct assay:GO:0006337 nucleosome
disassembly [PMID:16492771]"
/experiment="EXISTENCE:direct assay:GO:0008047 enzyme
activator activity [PMID:22308335]"
/experiment="EXISTENCE:direct assay:GO:0032153 cell
division site [PMID:25416945]"
/experiment="EXISTENCE:direct assay:GO:0032174 cellular
bud neck septin collar [PMID:30341817]"
/experiment="EXISTENCE:direct assay:GO:0032968 positive
regulation of transcription elongation by RNA polymerase
II [PMID:22308335]"
/experiment="EXISTENCE:direct assay:GO:0042393 histone
binding [PMID:17289584|PMID:21348863]"
/experiment="EXISTENCE:direct assay:GO:0051082 unfolded
protein binding [PMID:31062022]"
/experiment="EXISTENCE:genetic interaction:GO:0042274
ribosomal small subunit biogenesis [PMID:31062022]"
/experiment="EXISTENCE:mutant phenotype:GO:0006607
NLS-bearing protein import into nucleus [PMID:12456659]"
/experiment="EXISTENCE:mutant phenotype:GO:0007117 budding
cell bud growth [PMID:13680156]"
/experiment="EXISTENCE:mutant phenotype:GO:0031116
positive regulation of microtubule polymerization
[PMID:7622567]"
/experiment="EXISTENCE:mutant phenotype:GO:0098841 protein
localization to cell division site after cytokinesis
[PMID:25416945]"
/experiment="EXISTENCE:physical interaction:GO:0030332
cyclin binding [PMID:7622566]"
/note="Histone chaperone and assembly chaperone for
Rps6a/b; involved in histone exchange, replacing histone
H2A-H2B dimers or histone variant dimers from assembled
nucleosomes; promotes solubility of Rps6a, and 40S
ribosomal subunit biogenesis; role in transport of H2A and
H2B histones to the nucleus; regulates microtubule
dynamics during mitosis; interacts with mitotic cyclin
Clb2p; controls bud morphogenesis; phosphorylated by CK2;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="histone chaperone NAP1"
/protein_id="DAA09199.1"
/db_xref="SGD:S000001756"
/translation="MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNGNPVRAQA
QEQDDKIGTINEEDILANQPLLLQSIQDRLGSLVGQDSGYVGGLPKNVKEKLLSLKTL
QSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQEIVESL
NETELLVDEEEKAQNDSEEEQVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIG
LEYLTDGRPGFKLLFRFDSSANPFFTNDILCKTYFYQKELGYSGDFIYDHAEGCEISW
KDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPKIQNEDQDEELEEDL
EERLALDYSIGEQLKDKLIPRAVDWFTGAALEFEFEEDEEEADEDEDEEEDDDHGLED
DDGESAEEQDDFAGRPEQAPECKQS"
gene complement(526830..527231)
/gene="FMP46"
/locus_tag="YKR049C"
mRNA complement(526830..527231)
/gene="FMP46"
/locus_tag="YKR049C"
/product="putative redox protein"
CDS complement(526830..527231)
/gene="FMP46"
/locus_tag="YKR049C"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion
[PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:mutant phenotype:GO:0051051
negative regulation of transport [PMID:21912684]"
/note="Putative redox protein containing a thioredoxin
fold; the authentic, non-tagged protein is detected in
highly purified mitochondria in high-throughput studies"
/codon_start=1
/product="putative redox protein"
/protein_id="DAA09200.1"
/db_xref="SGD:S000001757"
/translation="MSFWKTLQRQPRTISLFTNDIASNIKSQKCLQLLKGDVSHRFDV
EIANRFPTWDQLQYMRTSCPQGPVSLQRQIPKLDSVLKYKHTDPTFGMDLQKCVQRGL
WNPKEALWVDWENKLVGNEPADIDKYIIQRK"
gene 527815..530484
/gene="TRK2"
/locus_tag="YKR050W"
/gene_synonym="RPD2"
mRNA 527815..530484
/gene="TRK2"
/locus_tag="YKR050W"
/gene_synonym="RPD2"
/product="Trk2p"
CDS 527815..530484
/gene="TRK2"
/locus_tag="YKR050W"
/gene_synonym="RPD2"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:14570869]"
/experiment="EXISTENCE:direct assay:GO:0015079 potassium
ion transmembrane transporter activity [PMID:2072919]"
/experiment="EXISTENCE:direct assay:GO:0030007
intracellular potassium ion homeostasis [PMID:2072919]"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/experiment="EXISTENCE:mutant phenotype:GO:0006874
intracellular calcium ion homeostasis [PMID:33640956]"
/experiment="EXISTENCE:mutant phenotype:GO:0042391
regulation of membrane potential [PMID:21424545]"
/note="Component of the Trk1p-Trk2p potassium transport
system; contributes to K(+) supply and maintenance of
plasma-membrane potential; TRK2 has a paralog, TRK1, that
arose from the whole genome duplication"
/codon_start=1
/product="Trk2p"
/protein_id="DAA09201.1"
/db_xref="SGD:S000001758"
/translation="MPTAKRTSSRASLALPFQLRLVHKKSWGHRLRDFISGFLKSCRP
IAKYVFPNFIVVHYIYLITLSIIGSILLYPCKNTAFIDVLFLAAGASTQGGLATKSTN
DFNLYQQIVVYVITLLSTPILIHGFLAFVRLYWFERYFDNIRDISKQNFKLRRTMTLQ
QRELSGSSGNAARSRSFKDNLFRGKFVSREDPRQSASDVPMDSPDTSALSSISPLNVS
SSKEESSDTQSSPPNFSSKRQPSDVDPRDIYKSIMMLQKQQEKSNANSTDSFSSETNG
PAFIVQERHERRAPHCSLKRHSVLPSSQELNKLAQTKSFQKLLGLRRDEGDHDYFDGA
PHKYMVTKKKKISRTQSCNIPTYTASPSPKTSGQVVENHRNLAKSAPSSFVDEEMSFS
PQESLNLQFQAHPPKPKRREGDIGHPFTRTMSTNYLSWQPTFGRNSVFIGLTKQQKEE
LGGVEYRALRLLCCILMVYYIGFNILAFVTIVPWACTRHHYSEIIRRNGVSPTWWGFF
TAMSAFSNLGLSLTADSMVSFDTAPYPLIFMMFFIIIGNTGFPIMLRFIIWIMFKTSR
DLSQFKESLGFLLDHPRRCFTLLFPSGPTWWLFTTLVVLNATDWILFIILDFNSAVVR
QVAKGYRALMGLFQSVCTRTAGFNVVDLSKLHPSIQVSYMLMMYVSVLPLAISIRRTN
VYEEQSLGLYDSGQDDENITHEDDIKETDHDGESEERDTVSTKSKPKKQSPKSFVGAH
LRRQLSFDLWYLFLGLFIICICEGRKIEDVNKPDFNVFAILFEVVSAYGTVGLSLGYP
NTNTSLSAQFTVLSKLVIIAMLIRGRNRGLPYTLDRAIMLPSDKLEQIDRLQDMKAKG
KLLAKVGEDPMTTYVKKRSHKLKKIATKFWGKH"
gene 530946..532202
/gene="HFL1"
/locus_tag="YKR051W"
mRNA 530946..532202
/gene="HFL1"
/locus_tag="YKR051W"
/product="Hfl1p"
CDS 530946..532202
/gene="HFL1"
/locus_tag="YKR051W"
/experiment="EXISTENCE:direct assay:GO:0005774 vacuolar
membrane [PMID:34088313]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:mutant phenotype:GO:0044395 protein
targeting to vacuolar membrane [PMID:34088313]"
/note="Vacuole membrane protein that interacts with Atg8p;
functions in the vacuolar membrane recruitment of Atg8p to
facilitate the degradation of vacuolar integral membrane
proteins during early-stationary vacuole turnover (EVT), a
general degradation process for vacuolar integral membrane
proteins when cells enter stationary phase; null mutant is
defective in stationary phase-induced vacuolar microdomain
formation; homolog of S. pombe hfl1; homolog of human
TMEM184"
/codon_start=1
/product="Hfl1p"
/protein_id="DAA09202.1"
/db_xref="SGD:S000001759"
/translation="MENKLLCWWLYWPCVYSSIIATIISFYTITRHLLNYRKPYEQRL
SIRILLLVPIFSVSCASGIIKPEAAQFYVDPIREFYEAFVIYTFFTFLTLLLGGERNI
ITVLSLNHAPTRHPIPLIGKICKPIDLSDPFDFLFVKKGILQYVWFKPFYCFGTLICS
AWKLPKFEIFLNVFYNISVTWSLYSLALFWKCLYPELTPYKPWLKFLCVKLIIFASYW
QSIIIQGLVVTGKLGTGNQDRTSGYVYKNGLLCIEMVPFAILHAVAFPWNKYTAFSIP
YGARMKFIYALKDFLGCGDLIWDFKQTLFAGPLYYNYRNFDPEAMDLLSTRQQSGATM
ERLKHGLRFTDNGRNSYWVAYGSIDNNLVPESIEESWEDDIAGQRTFPEDPNYPVVHD
YTMGHRYSRSMNDLRRDVQSRSSMAC"
gene complement(532550..533464)
/gene="MRS4"
/locus_tag="YKR052C"
mRNA complement(532550..533464)
/gene="MRS4"
/locus_tag="YKR052C"
/product="Fe(2+) transporter"
CDS complement(532550..533464)
/gene="MRS4"
/locus_tag="YKR052C"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005743
mitochondrial inner membrane [PMID:1703236]"
/experiment="EXISTENCE:direct assay:GO:0048250 iron import
into the mitochondrion [PMID:12902335]"
/experiment="EXISTENCE:mutant phenotype:GO:0005381 iron
ion transmembrane transporter activity [PMID:12902335]"
/note="Iron transporter of the mitochondrial carrier
family; mediates Fe2+ transport across the inner
mitochondrial membrane; active under low-iron conditions;
may transport other cations; protein abundance increases
in response to DNA replication stress; MRS4 has a paralog,
MRS3, that arose from the whole genome duplication"
/codon_start=1
/product="Fe(2+) transporter"
/protein_id="DAA09203.1"
/db_xref="SGD:S000001760"
/translation="MNTSELSIAEEIDYEALPSHAPLHSQLLAGAFAGIMEHSLMFPI
DALKTRVQAAGLNKAASTGMISQISKISTMEGSMALWKGVQSVILGAGPAHAVYFGTY
EFCKARLISPEDMQTHQPMKTALSGTIATIAADALMNPFDTVKQRLQLDTNLRVWNVT
KQIYQNEGFAAFYYSYPTTLAMNIPFAAFNFMIYESASKFFNPQNSYNPLIHCLCGGI
SGATCAALTTPLDCIKTVLQVRGSETVSIEIMKDANTFGRASRAILEVHGWKGFWRGL
KPRIVANIPATAISWTAYECAKHFLMKN"
gene complement(534067..535281)
/gene="YSR3"
/locus_tag="YKR053C"
/gene_synonym="LBP2"
mRNA complement(534067..535281)
/gene="YSR3"
/locus_tag="YKR053C"
/gene_synonym="LBP2"
/product="sphinganine kinase YSR3"
CDS complement(534067..535281)
/gene="YSR3"
/locus_tag="YKR053C"
/gene_synonym="LBP2"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:10477278|PMID:10531356]"
/experiment="EXISTENCE:direct assay:GO:0042392
sphingosine-1-phosphate phosphatase activity
[PMID:10856228]"
/experiment="EXISTENCE:direct assay:GO:0046839
phospholipid dephosphorylation [PMID:10856228]"
/experiment="EXISTENCE:mutant phenotype:GO:0030148
sphingolipid biosynthetic process [PMID:9353337]"
/note="Dihydrosphingosine 1-phosphate phosphatase;
membrane protein involved in sphingolipid metabolism; YSR3
has a paralog, LCB3, that arose from the whole genome
duplication"
/codon_start=1
/product="sphinganine kinase YSR3"
/protein_id="DAA09204.1"
/db_xref="SGD:S000001761"
/translation="MTIIQTVTELGVTEDTIKVQMAPSGGKHLLADPGNHPAEHFESQ
MSWLRFQTRQYLTRFTDNQSDFVHSLQKKHRTPFRDVYFKYTSLMGSHMFYVIVLPMP
VWLGYRDLTRDMIYVLGYSIYLSGYLKDYWCLPRPKSPPVDRITLSEYTTKEYGAPSS
HSANATAVSLLFFWRICLSDTLVWPTKLLLLSLVIFYYLTLVFGRVYCGMHGMLDLFS
GAAVGAICFFIRIWVVHALRNFQIGEHLWFPLLSVAWGLFILFNHVRPIDECPCFEDS
VAFIGVVSGLDCSDWLTERYGWNLVCSRYASCGSKVFLRPLVGVASVIVWKDVISKTA
VYTLLIKLLRFHDDRSEKVHFHNETSEEEECLLYSGVSKVEIVGRFLIYAGIPTTVFL
LCPVFFTWTNLR"
gene complement(535647..547925)
/gene="DYN1"
/locus_tag="YKR054C"
/gene_synonym="DHC1"
/gene_synonym="PAC6"
mRNA complement(535647..547925)
/gene="DYN1"
/locus_tag="YKR054C"
/gene_synonym="DHC1"
/gene_synonym="PAC6"
/product="dynein heavy chain"
CDS complement(535647..547925)
/gene="DYN1"
/locus_tag="YKR054C"
/gene_synonym="DHC1"
/gene_synonym="PAC6"
/experiment="EXISTENCE:direct assay:GO:0000235 astral
microtubule [PMID:16580990]"
/experiment="EXISTENCE:direct assay:GO:0005524 ATP binding
[PMID:25941405]"
/experiment="EXISTENCE:direct assay:GO:0005816 spindle
pole body [PMID:16580990]"
/experiment="EXISTENCE:direct assay:GO:0005881 cytoplasmic
microtubule [PMID:12566428|PMID:15965467]"
/experiment="EXISTENCE:direct assay:GO:0005938 cell cortex
[PMID:15642746]"
/experiment="EXISTENCE:direct assay:GO:0008569
minus-end-directed microtubule motor activity
[PMID:25941405|PMID:16873064]"
/experiment="EXISTENCE:genetic interaction:GO:0000070
mitotic sister chromatid segregation [PMID:7860634]"
/experiment="EXISTENCE:genetic interaction:GO:0030473
nuclear migration along microtubule [PMID:9201714]"
/experiment="EXISTENCE:mutant phenotype:GO:0000132
establishment of mitotic spindle orientation
[PMID:9281582]"
/experiment="EXISTENCE:mutant phenotype:GO:0008569
minus-end-directed microtubule motor activity
[PMID:25941405]"
/experiment="EXISTENCE:mutant phenotype:GO:0030473 nuclear
migration along microtubule [PMID:9201714]"
/experiment="EXISTENCE:mutant phenotype:GO:0040001
establishment of mitotic spindle localization
[PMID:21633107]"
/experiment="EXISTENCE:physical interaction:GO:0005868
cytoplasmic dynein complex [PMID:9658168]"
/note="Cytoplasmic heavy chain dynein; microtubule motor
protein; member of the AAA+ protein family, required for
anaphase spindle elongation; involved in spindle assembly,
chromosome movement, and spindle orientation during cell
division, targeted to microtubule tips by Pac1p; motility
along microtubules inhibited by She1p"
/codon_start=1
/product="dynein heavy chain"
/protein_id="DAA09205.1"
/db_xref="SGD:S000001762"
/translation="MCKNEARLANELIEFVAATVTGIKNSPKENEQAFIDYLHCQYLE
RFQFFLGLLDGREFDTLFVFLFEELDRTIVTIDIGEEAIYDANLANKKYSTLLIIKSR
SVIVDAEPIATQISAIYLPGPVNAGNLASIITHGVSSVFGQLIKSDTKTYSVETIDKT
RRKLDDISKQFQQLHTSIETPDLLAMVPSIIKLAVSKGATSHDYANYLPSNDLESMRF
LNILQSIANKWFLVLKQTLAIDRDIKNGSFLDEVEFWSNFYEVLKSLIEQTQSQEFQV
CLSVLTNAKRFHNLTNLLNEGSLSDKFKLADKYNQFLSSIPIDEVRQASNLEDLQELF
PVLASSLKKFRYSGYPVQRFVVLMDKISQEVMDAILSNLSDLFQLEYGSFLGLYEKSA
GMIEEWDDIVQDVNLLIREDLRKRAPQELLIQKLTFTSASVKATLDEILSTRKRFFSL
AETIKSISPSTYHEEIQRLYHPFEQIHDISVNFRLKLEQAESEFSKNMLDLEKKLQNT
LASFMDSDHCPTEKLSYLVKFKPLMELCPRIKVKVLENQQILLLEIKKDIRQLETGLE
LLPKILHVEALNNIPPISARISYFLNVQSRIDNIVQYLEALFGSNWNDTLEGRSISTS
IVQLRKETNPHDVFLHWLGNFPEKATANLLTTPILKLIRNNEDDYELKVNFDFALAAA
YSELRSLTYMAFQVPSHIVRIARTYMYLYPRAINLVELIQTFFSLSKSLSYTFYTNIF
LKRNVQTVWLLLQQILITPWESLQEESSEMSCSVHSLARLEKSIDGILSDYQILKNSE
PQFAKEFSGLKSFDGTADDLHEVEEIISNIQAIFENLFTKGLTNVSDHISTFNNLIIS
IILEKVRLNLKKMHFPKHVLKLSFNEGRITSSPSLAAMKRSLLKDIEALLNKVVLINF
LHDPDHPLSTTLTFNSLVIKLKDDIQNCIEQVQNLHCKINSYVKEWQKMEFLWQITEE
AFLEVVDNSTQRCFGILKGLLDSQSKFDLIISRNNFSKNLVLHTEDAQRHIRSKMDSW
ILYVSKHLLTIYERDARKLHEDMNRDREAVEDMDINFTSLKNITVIIEAVNVNKRHLT
ERDIQIKLLGSVMRALTKLKVRFPSHFVYIDQLDNDFSSLRQSLSYVEQELQKHRVVI
AKSLEEGVENINNLSQSLNESWSVRKPISPTLTPPEALKILEFFNESITKLKKKMHSV
AAAAKMLLIPVVLNDQLTHVVEEVKTYDLVWRSIKNLWEDVQRTFETPWCRVDVLLLQ
SDLANFLRRADELPRAVKQFEMYKSLFSQVNMLTSVNKILVELKDGALKPRHWNMIFR
DIGKRQIQKNLLDKLEFSLKDVMVLNLTLNEILLTKIIERAQKEFVIEKSLNRIKKFW
KEAQYEVIEHSSGLKLVREWDVLEQACKEDLEELVSMKASNYYKIFEQDCLDLESKLT
KLSEIQVNWVEVQFYWLDLYGILGENLDIQNFLPLETSKFKSLTSEYKMITTRAFQLD
TTIEVIHIPNFDTTLKLTIDSLKMIKSSLSTFLERQRRQFPRFYFLGNDDLLKIIGSG
KHHDQVSKFMKKMFGSIESIIFLEDFITGVRSVEGEVLNLNEKIELKDSIQAQEWLNI
LDTEIKLSVFTQFRDCLGQLKDGTDIEVVVSKYIFQAILLSAQVMWTELVEKCLQTNQ
FSKYWKEVDMKIKGLLDKLNKSSDNVKKKIEALLVEYLHFNNVIGQLKNCSTKEEARL
LWAKVQKFYQKNDTLDDLNSVFISQSGYLLQYKFEYIGIPERLIYTPLLLIGFATLTD
SLHQKYGGCFFGPAGTGKTETVKAFGQNLGRVVVVFNCDDSFDYQVLSRLLVGITQIG
AWGCFDEFNRLDEKVLSAVSANIQQIQNGLQVGKSHITLLEEETPLSPHTAVFITLNP
GYNGRSELPENLKKSFREFSMKSPQSGTIAEMILQIMGFEDSKSLASKIVHFLELLSS
KCSSMNHYHFGLRTLKGVLRNCSPLISEFGEGEKTVVESLKRVILPSLGDTDELVFKD
ELSKIFDSAGTPLNSKAIVQCLKDAGQRSGFSMSEEFLKKCMQFYYMQKTQQALILVG
KAGCGKTATWKTVIDAMAIFDGHANVVYVIDTKVLTKESLYGSMLKATLEWRDGLFTS
ILRRVNDDITGTFKNSRIWVVFDSDLDPEYVEAMNSVLDDNKILTLPNGERLPIPPNF
RILFETDNLDHTTPATITRCGLLWFSTDVCSISSKIDHLLNKSYEALDNKLSMFELDK
LKDLISDSFDMASLTNIFTCSNDLVHILGVRTFNKLETAVQLAVHLISSYRQWFQNLD
DKSLKDVITLLIKRSLLYALAGDSTGESQRAFIQTINTYFGHDSQELSDYSTIVIAND
KLSFSSFCSEIPSVSLEAHEVMRPDIVIPTIDTIKHEKIFYDLLNSKRGIILCGPPGS
GKTMIMNNALRNSSLYDVVGINFSKDTTTEHILSALHRHTNYVTTSKGLTLLPKSDIK
NLVLFCDEINLPKLDKYGSQNVVLFLRQLMEKQGFWKTPENKWVTIERIHIVGACNPP
TDPGRIPMSERFTRHAAILYLGYPSGKSLSQIYEIYYKAIFKLVPEFRSYTEPFARAS
VHLYNECKARYSTGLQSHYLFSPRELTRLVRGVYTAINTGPRQTLRSLIRLWAYEAWR
IFADRLVGVKEKNSFEQLLYETVDKYLPNQDLGNISSTSLLFSGLLSLDFKEVNKTDL
VNFIEERFKTFCDEELEVPMVIHESMVDHILRIDRALKQVQGHMMLIGASRTGKTILT
RFVAWLNGLKIVQPKIHRHSNLSDFDMILKKAISDCSLKESRTCLIIDESNILETAFL
ERMNTLLANADIPDLFQGEEYDKLLNNLRNKTRSLGLLLDTEQELYDWFVGEIAKNLH
VVFTICDPTNNKSSAMISSPALFNRCIINWMGDWDTKTMSQVANNMVDVIPMEFTDFI
VPEVNKELVFTEPIQTIRDAVVNILIHFDRNFYQKMKVGVNPRSPGYFIDGLRALVKL
VTAKYQDLQENQRFVNVGLEKLNESVLKVNELNKTLSKKSTELTEKEKEARSTLDKML
MEQNESERKQEATEEIKKILKVQEEDIRKRKEVVMKSIQDIEPTILEAQRGVKNIKKQ
QLTEIRSMVNPPSGVKIVMEAVCAILGYQFSNWRDIQQFIRKDDFIHNIVHYDTTLHM
KPQIRKYMEEEFLSDPNFTYETINRASKACGPLYQWVNAQINFSKVLENVDPLRQEMK
RIEFESLKTKANLLAAEEMTQDLEASIEVSKRKYSLLIRDVEAIKTEMSNVQANLDRS
ISLVKSLTFEKERWLNTTKQFSKTSQELIGNCIISSIYETYFGHLNERERADMLVILK
RLLGKFAVKYDVNYRFIDYLVTLDEKMKWLECGLDKNDYFLENMSIVMNSQDAVPFLL
DPSSHMITVISNYYGNKTVLLSFLEEGFVKRLENAIRFGSVVIIQDGEFFDPIISRLI
SREFNHAGNRVTVEIGDHEVDVSGDFKLFIHSCDPSGDIPIFLRSRVRLVHFVTNKES
IETRIFDITLTEENAEMQRKREDLIKLNTEYKLKLKNLEKRLLEELNNSQGNMLENDE
LMVTLNNLKKEAMNIEKKLSESEEFFPQFDNLVEEYSIIGKHSVKIFSMLEKFGQFHW
FYGISIGQFLSCFKRVFIKKSRETRAARTRVDEILWLLYQEVYCQFSTALDKKFKMIM
AMTMFCLYKFDIESEQYKEAVLTMIGVLSESSDGVPKLTVDTNNDLRYLWDYVTTKSY
ISALNWFKNEFFVDEWNIADVVANSENNYFTMASERDVDGTFKLIELAKASKESLKII
PLGSIENLNYAQEEISKSKIEGGWILLQNIQMSLSWVKTYLHKHVEETKAAEEHEKFK
MFMTCHLTGDKLPAPLLQRTDRFVYEDIPGILDTVKDLWGSQFFTGKISGVWSVYCTF
LLSWFHALITARTRLVPHGFSKKYYFNDCDFQFASVYLENVLATNSTNNIPWAQVRDH
IATIVYGGKIDEEKDLEVVAKLCAHVFCGSDNLQIVPGVRIPQPLLQQSEEEERARLT
AILSNTIEPADSLSSWLQLPRESILNYERLQAKEVASSTEQLLQEM"
gene 548216..549091
/gene="RHO4"
/locus_tag="YKR055W"
mRNA 548216..549091
/gene="RHO4"
/locus_tag="YKR055W"
/product="Rho family GTPase RHO4"
CDS 548216..549091
/gene="RHO4"
/locus_tag="YKR055W"
/EC_number="3.6.5.2"
/experiment="EXISTENCE:direct assay:GO:0000131 incipient
cellular bud site [PMID:18417612]"
/experiment="EXISTENCE:direct assay:GO:0003924 GTPase
activity [PMID:10526184]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:18417612]"
/experiment="EXISTENCE:direct assay:GO:0005935 cellular
bud neck [PMID:18417612|PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/experiment="EXISTENCE:genetic interaction:GO:0030011
maintenance of cell polarity [PMID:1448099]"
/experiment="EXISTENCE:genetic interaction:GO:0090338
positive regulation of formin-nucleated actin cable
assembly [PMID:12810699]"
/experiment="EXISTENCE:physical interaction:GO:0090337
regulation of formin-nucleated actin cable assembly
[PMID:9184220]"
/note="Non-essential small GTPase; member of the Rho/Rac
subfamily of Ras-like proteins; likely to be involved in
the establishment of cell polarity; has long N-terminal
extension that plays an important role in Rho4p function
and is shared with Rho4 homologs in other yeasts and
filamentous fungi"
/codon_start=1
/product="Rho family GTPase RHO4"
/protein_id="DAA09206.1"
/db_xref="SGD:S000001763"
/translation="MNTLLFKRKGGNCGNESNIVSQGSPSSSNLPESPGTLDEKNLPR
LPTPFARSLSTIPSYEQMKRTNKLPDYHLKIVVVGDGAVGKTCLLISYVQGTFPTDYI
PTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLRPLSYTNADVLMVCYSVGSKTSL
KNVEDLWFPEVKHFCPSTPIMLVGLKSDLYEADNLSDLVEPSSAESLAKRLGAFAHIQ
CSARLKENIDEVFETAIHTLLSDSLYAPREPTHTIKNPFKRNTTRSDIDSSTGDTSVS
ISGTKRLRKNKCIIM"
gene 549448..551367
/gene="TRM2"
/locus_tag="YKR056W"
/gene_synonym="NUC2"
/gene_synonym="NUD1"
/gene_synonym="RNC1"
mRNA 549448..551367
/gene="TRM2"
/locus_tag="YKR056W"
/gene_synonym="NUC2"
/gene_synonym="NUD1"
/gene_synonym="RNC1"
/product="tRNA (uracil(54)-C(5))-methyltransferase"
CDS 549448..551367
/gene="TRM2"
/locus_tag="YKR056W"
/gene_synonym="NUC2"
/gene_synonym="NUD1"
/gene_synonym="RNC1"
/EC_number="2.1.1.35"
/experiment="EXISTENCE:direct assay:GO:0000014
single-stranded DNA endodeoxyribonuclease activity
[PMID:17205207]"
/experiment="EXISTENCE:direct assay:GO:0006400 tRNA
modification [PMID:10864043]"
/experiment="EXISTENCE:direct assay:GO:0030697 tRNA
(uracil(54)-C5)-methyltransferase activity, S-adenosyl
methionine-dependent [PMID:10864043]"
/experiment="EXISTENCE:direct assay:GO:0051908
double-stranded DNA 5'-3' exodeoxyribonuclease activity
[PMID:17205207]"
/experiment="EXISTENCE:mutant phenotype:GO:0030697 tRNA
(uracil(54)-C5)-methyltransferase activity, S-adenosyl
methionine-dependent [PMID:10864043]"
/experiment="EXISTENCE:mutant phenotype:GO:0080009 mRNA
methylation [PMID:37181630]"
/note="tRNA methyltransferase; 5-methylates the uridine
residue at position 54 of tRNAs and may also have a role
in tRNA stabilization or maturation; involved in the
methylation of guanosine and uridine ribonucleosides in
mRNA; endo-exonuclease with a role in DNA repair"
/codon_start=1
/product="tRNA (uracil(54)-C(5))-methyltransferase"
/protein_id="DAA09207.1"
/db_xref="SGD:S000001764"
/translation="MYEQFEFSFFFFENSDNKVKYKAHLISSIKRWSIITCMRCFWTV
QKSIFKARFFACRNFVKKHNYKLISTMTGSTEMVPPTMKHTVDNKRLSSPLTDSGNRR
TKKPKLRKYKAKKVETTSPMGVLEFEVNDLLKSQNLSREQVLNDVTSILNDKSSTDGP
IVLQYHREVKNVKVLEITSNGNGLALIDNPVETEKKQVVIIPFGLPGDVVNIKVFKTH
PYYVESDLLDVVEKSPMRRDDLIRDKYFGKSSGSQLEFLTYDDQLELKRKTIMNAYKF
FAPRLVAEKLLPPFDTTVASPLQFGYRTKITPHFDMPKRKQKELSVRPPLGFGQKGRP
QWRKDTLDIGGHGSILDIDECVLATEVLNKGLTNERRKFEQEFKNYKKGATILLRENT
TILDPSKPTLEQLTEEASRDENGDISYVEVEDKKNNVRLAKTCVTNPRQIVTEYVDGY
TFNFSAGEFFQNNNSILPIVTKYVRDNLQAPAKGDDNKTKFLVDAYCGSGLFSICSSK
GVDKVIGVEISADSVSFAEKNAKANGVENCRFIVGKAEKLFESIDTPSENTSVILDPP
RKGCDELFLKQLAAYNPAKIIYISCNVHSQARDVEYFLKETENGSAHQIESIRGFDFF
PQTHHVESVCIMKRI"
gene 551657..552242
/gene="RPS21A"
/locus_tag="YKR057W"
/gene_synonym="RPS25"
mRNA join(551657..551680,552003..552242)
/gene="RPS21A"
/locus_tag="YKR057W"
/gene_synonym="RPS25"
/product="ribosomal 40S subunit protein S21A"
CDS join(551657..551680,552003..552242)
/gene="RPS21A"
/locus_tag="YKR057W"
/gene_synonym="RPS25"
/experiment="EXISTENCE:direct assay:GO:0003735 structural
constituent of ribosome [PMID:3533916]"
/experiment="EXISTENCE:direct assay:GO:0022627 cytosolic
small ribosomal subunit [PMID:3533916]"
/experiment="EXISTENCE:mutant phenotype:GO:0000447
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from
5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:14627813]"
/experiment="EXISTENCE:mutant phenotype:GO:0000461
endonucleolytic cleavage to generate mature 3'-end of
SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
[PMID:14627813]"
/note="Protein component of the small (40S) ribosomal
subunit; homologous to mammalian ribosomal protein S21, no
bacterial homolog; RPS21A has a paralog, RPS21B, that
arose from the whole genome duplication"
/codon_start=1
/product="ribosomal 40S subunit protein S21A"
/protein_id="DAA09208.1"
/db_xref="SGD:S000001765"
/translation="MENDKGQLVELYVPRKCSATNRIIKADDHASVQINVAKVDEEGR
AIPGEYVTYALSGYVRSRGESDDSLNRLAQNDGLLKNVWSYSR"
gene 552770..554620
/gene="GLG1"
/locus_tag="YKR058W"
mRNA 552770..554620
/gene="GLG1"
/locus_tag="YKR058W"
/product="glycogenin glucosyltransferase GLG1"
CDS 552770..554620
/gene="GLG1"
/locus_tag="YKR058W"
/EC_number="2.4.1.186"
/experiment="EXISTENCE:genetic interaction:GO:0005978
glycogen biosynthetic process [PMID:8524228]"
/experiment="EXISTENCE:genetic interaction:GO:0008466
glycogenin glucosyltransferase activity [PMID:8524228]"
/note="Glycogenin glucosyltransferase; self-glucosylating
initiator of glycogen synthesis, also glucosylates
n-dodecyl-beta-D-maltoside; SWAT-GFP and mCherry fusion
proteins localize to the cell periphery and vacuole
respectively; similar to mammalian glycogenin; GLG1 has a
paralog, GLG2, that arose from the whole genome
duplication"
/codon_start=1
/product="glycogenin glucosyltransferase GLG1"
/protein_id="DAA09209.1"
/db_xref="SGD:S000001766"
/translation="MYKKLAIATLLYSADYLPGVFALGHQVNKLLEEAGKKGDIETCL
IVTTSLFNGTLSELAKNILQSIYTKIVLVEPLNCQEESIQKNSENLALLERPELSFAL
IKARLWELTQFEQVLYLDSDTLPLNKEFLKLFDIMSKQTTSQVGAIADIGWPDMFNSG
VMMLIPDADTASVLQNYIFENTSIDGSDQGILNQFFNQNCCTDELVKDSFSREWVQLS
FTYNVTIPNLGYQSSPAMNYFKPSIKLIHFIGKHKPWSLWSQKNFIKNEYHDQWNEVY
EEFKEEHQLNNEVSKPKISDSDKTETPETITPVDAPPSNEPTTNQEIDTISTVEENVD
NQNAEPVPNSDHSPAPNPVPLDFTKWLTTFINKDHLTNQPVNESREYSKENDNNIINS
SSNRDQESPPNSTQELNSSYSVVSTQADSDEHQNAEEEDSTTDNASNSGEESHLDDIS
TAASSNNNVSNQPDGKNFSNSKENNISVESSPSNPEQKRSTDNIQKPSVSTNDLPDDV
EPHTSVDDNIQYLEKDKEGYEEFLPDVYESNAIDNEEEFFDDDARDATEGETKTSAVA
DKQEDMKLTAEETNQPQQEMPNFKFDWEDSDYLSKVERCFPDDIFEYAVE"
gene 554987..556174
/gene="TIF1"
/locus_tag="YKR059W"
mRNA 554987..556174
/gene="TIF1"
/locus_tag="YKR059W"
/product="translation initiation factor eIF4A"
CDS 554987..556174
/gene="TIF1"
/locus_tag="YKR059W"
/experiment="EXISTENCE:direct assay:GO:0003724 RNA
helicase activity [PMID:1502180]"
/experiment="EXISTENCE:direct assay:GO:0003743 translation
initiation factor activity [PMID:1502180]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:16622836]"
/experiment="EXISTENCE:direct assay:GO:0006413
translational initiation [PMID:1502180]"
/experiment="EXISTENCE:direct assay:GO:0008186
ATP-dependent activity, acting on RNA [PMID:24471916]"
/experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
stress granule [PMID:26777405]"
/experiment="EXISTENCE:direct assay:GO:1901195 positive
regulation of formation of translation preinitiation
complex [PMID:30281017|PMID:29192585]"
/experiment="EXISTENCE:mutant phenotype:GO:0003724 RNA
helicase activity [PMID:1502180]"
/experiment="EXISTENCE:mutant phenotype:GO:0003743
translation initiation factor activity [PMID:1502180]"
/experiment="EXISTENCE:mutant phenotype:GO:0006413
translational initiation [PMID:1502180]"
/experiment="EXISTENCE:mutant phenotype:GO:0016281
eukaryotic translation initiation factor 4F complex
[PMID:2648398|PMID:10409745]"
/note="Translation initiation factor eIF4A; DEAD-box RNA
helicase that couples ATPase activity to mRNA binding and
unwinding; ATP hydrolysis accelerates the recruitment of
mRNA during 48S preinitiation complex (PIC) assembly;
ATPase activity stimulated by either eIF4G1 or by the PIC
in an eIF3g and eIFGi subunit-dependent manner,
independent of eIF4E and eIF4G; subunit of the mRNA
cap-binding protein complex (eIF4F) with eIF4E and eIF4G;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="translation initiation factor eIF4A"
/protein_id="DAA09210.1"
/db_xref="SGD:S000001767"
/translation="MSEGITDIEESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEE
PSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTREL
ALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQIVVGTPGRVFDNIQRRRFR
TDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRN
PVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEEL
TTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVIN
YDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIAT
LLN"
gene 556518..557342
/gene="UTP30"
/locus_tag="YKR060W"
mRNA 556518..557342
/gene="UTP30"
/locus_tag="YKR060W"
/product="Utp30p"
CDS 556518..557342
/gene="UTP30"
/locus_tag="YKR060W"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:14562095|PMID:22588997]"
/experiment="EXISTENCE:direct assay:GO:0030686 90S
preribosome [PMID:12150911|PMID:22588997]"
/experiment="EXISTENCE:genetic interaction:GO:0000462
maturation of SSU-rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:22588997]"
/experiment="EXISTENCE:physical interaction:GO:0042274
ribosomal small subunit biogenesis [PMID:21724601]"
/note="Subunit of U3-containing 90S preribosome complex;
complex is involved in production of 18S rRNA and assembly
of small ribosomal subunit; Utp30p is peripherally
associated with 90S preribosome and appears partially
redundant with its paralog Cic1p"
/codon_start=1
/product="Utp30p"
/protein_id="DAA09211.1"
/db_xref="SGD:S000001768"
/translation="MVESNDIIKSGLAEKALKALILQCEENPSLKNDKDIHIIINTGK
KMGINRDNIPRIIPLTKYKLFKPRDLNILLITKDPSALYRETLTKDEHTSELFKEIIS
VKNLRRRFKGSKLTQLYKDFDLVVADYRVHHLLPEVLGSRFYHGSKKLPYMIRMSKEV
KLKRQQMVEKCDPIYVRAQLRSICKNTSYIPNNDNCLSVRVGYIQKHSIPEILQNIQD
TINFLTDKSKRPQGGVIKGGIISIFVKTSNSTSLPIYQFSEARENQKNEDLSDIKL"
gene 557677..558954
/gene="KTR2"
/locus_tag="YKR061W"
mRNA 557677..558954
/gene="KTR2"
/locus_tag="YKR061W"
/product="mannosyltransferase KTR2"
CDS 557677..558954
/gene="KTR2"
/locus_tag="YKR061W"
/experiment="EXISTENCE:direct assay:GO:0000030
mannosyltransferase activity [PMID:8631921]"
/experiment="EXISTENCE:direct assay:GO:0005794 Golgi
apparatus [PMID:8631921]"
/experiment="EXISTENCE:mutant phenotype:GO:0000032 cell
wall mannoprotein biosynthetic process [PMID:8631921]"
/experiment="EXISTENCE:mutant phenotype:GO:0006487 protein
N-linked glycosylation [PMID:8631921]"
/note="Mannosyltransferase involved in N-linked protein
glycosylation; member of the KRE2/MNT1 mannosyltransferase
family; KTR2 has a paralog, YUR1, that arose from the
whole genome duplication"
/codon_start=1
/product="mannosyltransferase KTR2"
/protein_id="DAA09212.1"
/db_xref="SGD:S000001769"
/translation="MQICKVFLTQVKKLLFVSLLFCLIAQTCWLALVPYQRQLSLDSY
FFRRSREVSSRYDFTRRRHMNQTLKLSSNTYNDEPLNKTKGIKNQRENATLLMLVRNW
ELSGALRSMRSLEDRFNKNYQYDWTFLNDVPFDQEFIEATTAMASGRTQYALIPAEDW
NRPSWINETLFEEALQLMEEKNILYGGSKSYRNMCRFNSGFFFRQKILDPYDFYFRVE
PDVEYFCDFPYDPFKVMRQNNKKYGFVITMYEYEDTIPSLWEAVEEYLEETESADIDM
ESNAFGFVSNFDFIGKSFGVIDSNSGYNLCHFWTNFEIGDLNFFRSEKYIRFFEYLDS
KGGFYYERWGDAPVHSIAASLLLKKDEIIHFDELGYKHMPFGTCPSAYYLRLQQRCLC
DSNHPDNIDLNVISCLRRWWKDGSGKYFLKHDS"
gene complement(559016..559366)
/gene="SNR42"
/locus_tag="YNCK0020C"
ncRNA complement(559016..559366)
/ncRNA_class="snoRNA"
/gene="SNR42"
/locus_tag="YNCK0020C"
/product="SNR42"
/experiment="EXISTENCE:curator inference:GO:0005730
nucleolus [PMID:9160748]"
/experiment="EXISTENCE:mutant phenotype:GO:0030559 rRNA
pseudouridylation guide activity [PMID:9160748]"
/experiment="EXISTENCE:mutant phenotype:GO:0031118 rRNA
pseudouridine synthesis [PMID:9160748]"
/experiment="EXISTENCE:physical interaction:GO:0031429 box
H/ACA snoRNP complex [PMID:15923376|PMID:9472021]"
/note="H/ACA box small nucleolar RNA (snoRNA); guides
pseudouridylation of large subunit (LSU) rRNA at position
U2975"
/db_xref="SGD:S000006502"
gene 559666..560652
/gene="TFA2"
/locus_tag="YKR062W"
mRNA 559666..560652
/gene="TFA2"
/locus_tag="YKR062W"
/product="transcription factor TFIIE subunit TFA2"
CDS 559666..560652
/gene="TFA2"
/locus_tag="YKR062W"
/experiment="EXISTENCE:direct assay:GO:0000993 RNA
polymerase II complex binding [PMID:8702741]"
/experiment="EXISTENCE:direct assay:GO:0001097 TFIIH-class
transcription factor complex binding [PMID:8702741]"
/experiment="EXISTENCE:direct assay:GO:0003697
single-stranded DNA binding [PMID:9271406]"
/experiment="EXISTENCE:direct assay:GO:0005673
transcription factor TFIIE complex
[PMID:1429681|PMID:7961670]"
/experiment="EXISTENCE:direct assay:GO:0006366
transcription by RNA polymerase II
[PMID:1331084|PMID:1429681|PMID:7961670]"
/experiment="EXISTENCE:direct assay:GO:0097550
transcription preinitiation complex [PMID:22751016]"
/experiment="EXISTENCE:genetic interaction:GO:0006366
transcription by RNA polymerase II [PMID:9405484]"
/experiment="EXISTENCE:physical interaction:GO:0005673
transcription factor TFIIE complex [PMID:9188494]"
/note="TFIIE small subunit; involved in RNA polymerase II
transcription initiation"
/codon_start=1
/product="transcription factor TFIIE subunit TFA2"
/protein_id="DAA09213.1"
/db_xref="SGD:S000001770"
/translation="MSKNRDPLLANLNAFKSKVKSAPVIAPAKVGQKKTNDTVITIDG
NTRKRTASERAQENTLNSAKNPVLVDIKKEAGSNSSNAISLDDDDDDEDFGSSPSKKV
RPGSIAAAALQANQTDISKSHDSSKLLWATEYIQKKGKPVLVNELLDYLSMKKDDKVI
ELLKKLDRIEFDPKKGTFKYLSTYDVHSPSELLKLLRSQVTFKGISCKDLKDGWPQCD
ETINQLEEDSKILVLRTKKDKTPRYVWYNSGGNLKCIDEEFVKMWENVQLPQFAELPR
KLQDLGLKPASVDPATIKRQTKRVEVKKKRQRKGKITNTHMTGILKDYSHRV"
gene complement(560789..562297)
/gene="LAS1"
/locus_tag="YKR063C"
mRNA complement(560789..562297)
/gene="LAS1"
/locus_tag="YKR063C"
/product="rRNA-processing protein LAS1"
CDS complement(560789..562297)
/gene="LAS1"
/locus_tag="YKR063C"
/experiment="EXISTENCE:direct assay:GO:0000448 cleavage in
ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA
transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
[PMID:26638174]"
/experiment="EXISTENCE:direct assay:GO:0004519
endonuclease activity [PMID:26638174]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:22083961|PMID:8582632]"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:23175604]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:22083961]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:mutant phenotype:GO:0000448
cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of
tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA,
LSU-rRNA) [PMID:23175604]"
/experiment="EXISTENCE:mutant phenotype:GO:0000460
maturation of 5.8S rRNA [PMID:22083961]"
/experiment="EXISTENCE:mutant phenotype:GO:0000470
maturation of LSU-rRNA [PMID:22083961]"
/experiment="EXISTENCE:physical interaction:GO:0030687
preribosome, large subunit precursor [PMID:23175604]"
/note="Endonuclease involved in pre-rRNA processing at
both ends of ITS2; functions with Grc3p in a conserved
mechanism to cleave pre-rRNA at a specific site during
rRNA processing and ribosome biogenesis; may coordinate
the action of the Rat1p-Rai1p exoRNAse; required for the
G1/S cell cycle transition; human ortholog is Las1L;
mutants require the SSD1-v allele for viability"
/codon_start=1
/product="rRNA-processing protein LAS1"
/protein_id="DAA09214.1"
/db_xref="SGD:S000001771"
/translation="MIPPRIVPWRDFAELEELKLWFYPKSKGTIEDKRQRAVQRVQSY
RLKGSQYLPHVVDSTAQITCAVLLDEKEACLGVHQDSIPIRLSYVMALIRFVNGLLDP
TQQSQFAIPLHTLAAKIGLPSWFVDLRHWGTHERDLPGLEMLRWAANEALSWLYDHYW
NDEELEDDRDDDDDDDDTGYGYRRNDKLEKYMESLTKTLDKWKRLRNEFLEYKWVWEN
ANDSLITSSNFSGDNLVNYDAEKRKSSHASSSETMIRENLRQWQELWKLSIYHNVVLE
KFFNNYDPLLLKVLMLNLNNFDWKVIEWVARNYRTQQDDSNITTILKRKFNAWKELQK
RLLDVIINNLNNKNFKNKWQNWEKLIDENASYLILYFCQSMLAKLETEKITGNSWRNK
KRRKQIDSTVEIEAKLKENIDNLSLRFNEGEIKLYDFIPAEKDSVPLKKEVSPALKAD
TNDILGDLASLKQRMSSFGTVGKKNKQEENRATPVKNWSRVQNWKPKPFGVL"
gene 562547..565138
/gene="OAF3"
/locus_tag="YKR064W"
mRNA 562547..565138
/gene="OAF3"
/locus_tag="YKR064W"
/product="Oaf3p"
CDS 562547..565138
/gene="OAF3"
/locus_tag="YKR064W"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095|PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095|PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:mutant phenotype:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:17551510]"
/note="Putative transcriptional repressor with
Zn(2)-Cys(6) finger; negatively regulates transcription in
response to oleate levels, based on mutant phenotype and
localization to oleate-responsive promoters; the
authentic, non-tagged protein is detected in highly
purified mitochondria in high-throughput studies; forms
nuclear foci upon DNA replication stress"
/codon_start=1
/product="Oaf3p"
/protein_id="DAA09215.1"
/db_xref="SGD:S000001772"
/translation="MGYDSQVRTKKRHRITVVCTNCKKRKSKCDRTKPCGTCVRLGDV
DSCVYLTDSSGQPESSPSLNDADPLRKQSTPAERISPGFIKKRRSSQTRQDEDHWQRV
RELENQSSLYYLPIHEETPFFIDLIPNGFYLETKRSADNLFGLFTDRAIENRDPYLQA
MVTFRSIAIKKMMDKLGSNGNNVKNGSLPKSFEALSTFDADDERHISDDVVGKGNNFR
MHQTIHKSLFNKFAQYRENNAKKFSSETILAKDYLPPLKILESEVLALFEEKIYNMIP
IFDMKVLRHEITIFYQNIVEKGNPISIKHYDHMVFCIILLIIKICRLSVQFSKLTPYI
YPVLQEIDTSKFLALVKHYLFETKVLRKCNLLQLQCLILLRFLHWCAPEDGDGPETQY
CQILMGTIISSCKEMGINWYCFSHPEKYSFKINRHTRPSYDIMKPSDYISVFRKIWSY
VLFWDRKMCFISGEECQIGKTLQCHFKEEADTPTWYIRMLTLDNLMKKINDTLNDDPG
KVDLNLLHRLINDLKRNFHILKSLSKNEKETMRHFDFEMEWIIDLFSLSLLHGEMIFY
EYDCNITKFYKSFQDLWDMVIHISEKCYNYFFNSDALEVDSLTKFYTNRIVEIVANKV
LVIVPAFILRGDRFKTIQYADKKKMIEFLYGVSSVYFNEFGFEYYRCFRKMFTAKIAY
KILNRSCEKDAWRIILKFLLNELKLEDNGDSYIDYNDMRLNDICPIILEFQETVQKYD
GYRPDILSIWNNEFYPIGKYNDDMTGFKFQMRIKEMQEFLDMEKYSDRFNIFSSFYDH
ASSQLAKHTEVDTNISITNEQVAEIPQKELLQQPLAPALPVNDLIVSEFDVIEDIFDP
VDFVSFF"
gene complement(565299..565892)
/gene="PAM17"
/locus_tag="YKR065C"
/gene_synonym="FMP18"
mRNA complement(565299..565892)
/gene="PAM17"
/locus_tag="YKR065C"
/gene_synonym="FMP18"
/product="Pam17p"
CDS complement(565299..565892)
/gene="PAM17"
/locus_tag="YKR065C"
/gene_synonym="FMP18"
/experiment="EXISTENCE:direct assay:GO:0001405 PAM
complex, Tim23 associated import motor [PMID:16107694]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:mutant phenotype:GO:0030150 protein
import into mitochondrial matrix [PMID:16107694]"
/note="Constituent of the TIM23 complex; proposed
alternatively to be a component of the import motor (PAM
complex) or to interact with and modulate the core TIM23
(Translocase of the Inner mitochondrial Membrane) complex;
protein abundance increases in response to DNA replication
stress"
/codon_start=1
/product="Pam17p"
/protein_id="DAA09216.1"
/db_xref="SGD:S000001773"
/translation="MFTSAIRLSSQRLFASQPSVTAAALRSTATTLPLRSYSQPASLQ
DSSILTWSDFFKLRKQQRRINVGSSLFTALLGCNVSWAYLSTMEIDPTQMLFGFDPLT
VISAGIIASGALGYLLGPIVGSQVFKLSHNQQLAQFNNKNKEFLKHIINNRVDASSQS
FSNPVPDYYGEKIGSLKEYKQWLRDCHAYAKKAKEFL"
gene complement(566113..567198)
/gene="CCP1"
/locus_tag="YKR066C"
mRNA complement(566113..567198)
/gene="CCP1"
/locus_tag="YKR066C"
/product="cytochrome-c peroxidase"
CDS complement(566113..567198)
/gene="CCP1"
/locus_tag="YKR066C"
/EC_number="1.11.1.5"
/experiment="EXISTENCE:direct assay:GO:0004130
cytochrome-c peroxidase activity
[PMID:21334283|PMID:17580971]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion
[PMID:11914276|PMID:14576278|PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005758
mitochondrial intermembrane space [PMID:6290489]"
/experiment="EXISTENCE:mutant phenotype:GO:0004130
cytochrome-c peroxidase activity
[PMID:10589830|PMID:21334283]"
/experiment="EXISTENCE:mutant phenotype:GO:0034599
cellular response to oxidative stress [PMID:10589830]"
/note="Mitochondrial cytochrome-c peroxidase; degrades
reactive oxygen species in mitochondria; acts as hydrogen
peroxide sensor in mitochondria, involved in the response
to oxidative stress"
/codon_start=1
/product="cytochrome-c peroxidase"
/protein_id="DAA09217.1"
/db_xref="SGD:S000001774"
/translation="MTTAVRLLPSLGRTAHKRSLYLFSAAAAAAAAATFAYSQSQKRS
SSSPGGGSNHGWNNWGKAAALASTTPLVHVASVEKGRSYEDFQKVYNAIALKLREDDE
YDNYIGYGPVLVRLAWHTSGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLE
PIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDA
DYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGPWGAANNVFTNEFYLNLLNE
DWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFE
KLLENGITFPKDAPSPFIFKTLEEQGL"
gene 567918..570149
/gene="GPT2"
/locus_tag="YKR067W"
/gene_synonym="GAT1"
mRNA 567918..570149
/gene="GPT2"
/locus_tag="YKR067W"
/gene_synonym="GAT1"
/product="bifunctional
glycerol-3-phosphate/glycerone-phosphate O-acyltransferase
GPT2"
CDS 567918..570149
/gene="GPT2"
/locus_tag="YKR067W"
/gene_synonym="GAT1"
/EC_number="2.3.1.15"
/EC_number="2.3.1.42"
/experiment="EXISTENCE:direct assay:GO:0004366
glycerol-3-phosphate O-acyltransferase activity
[PMID:11544256]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276]"
/experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
reticulum
[PMID:11914276|PMID:14562095|PMID:19525420|PMID:22267742|P
MID:26928762|PMID:9401016]"
/experiment="EXISTENCE:direct assay:GO:0005811 lipid
droplet [PMID:22267742|PMID:9401016]"
/experiment="EXISTENCE:direct assay:GO:0008654
phospholipid biosynthetic process [PMID:11544256]"
/experiment="EXISTENCE:direct assay:GO:0016287
glycerone-phosphate O-acyltransferase activity
[PMID:11544256]"
/experiment="EXISTENCE:mutant phenotype:GO:0004366
glycerol-3-phosphate O-acyltransferase activity
[PMID:11544256]"
/experiment="EXISTENCE:mutant phenotype:GO:0008654
phospholipid biosynthetic process [PMID:11544256]"
/experiment="EXISTENCE:mutant phenotype:GO:0090207
regulation of triglyceride metabolic process
[PMID:31421179]"
/note="Glycerol-3-phosphate/dihydroxyacetone phosphate
sn-1 acyltransferase; located in lipid particles and the
ER; involved in the stepwise acylation of
glycerol-3-phosphate and dihydroxyacetone in lipid
biosynthesis; the most conserved motifs and functionally
relevant residues are oriented towards the ER lumen"
/codon_start=1
/product="bifunctional
glycerol-3-phosphate/glycerone-phosphate O-acyltransferase
GPT2"
/protein_id="DAA09218.1"
/db_xref="SGD:S000001775"
/translation="MSAPAADHNAAKPIPHVPQASRRYKNSYNGFVYNIHTWLYDVSV
FLFNILFTIFFREIKVRGAYNVPEVGVPTILVCAPHANQFIDPALVMSQTRLLKTSAG
KSRSRMPCFVTAESSFKKRFISFFGHAMGGIPVPRIQDNLKPVDENLEIYAPDLKNHP
EIIKGRSKNPQTTPVNFTKRFSAKSLLGLPDYLSNAQIKEIPDDETIILSSPFRTSKS
KVVELLTNGTNFKYAEKIDNTETFQSVFDHLHTKGCVGIFPEGGSHDRPSLLPIKAGV
AIMALGAVAADPTMKVAVVPCGLHYFHRNKFRSRAVLEYGEPIVVDGKYGEMYKDSPR
ETVSKLLKKITNSLFSVTENAPDYDTLMVIQAARRLYQPVKVRLPLPAIVEINRRLLF
GYSKFKDDPRIIHLKKLVYDYNRKLDSVGLKDHQVMQLKTTKLEALRCFVTLIVRLIK
FSVFAILSLPGSILFTPIFIICRVYSEKKAKEGLKKSLVKIKGTDLLATWKLIVALIL
APILYVTYSILLIILARKQHYCRIWVPSNNAFIQFVYFYALLVFTTYSSLKTGEIGVD
LFKSLRPLFVSIVYPGKKIEEIQTTRKNLSLELTAVCNDLGPLVFPDYDKLATEIFSK
RDGYDVSSDAESSISRMSVQSRSRSSSIHSIGSLASNALSRVNSRGSLTDIPIFSDAK
QGQWKSEGETSEDEDEFDEKNPAIVQTARSSDLNKENSRNTNISSKIASLVRQKREHE
KKE"
gene complement(570328..570909)
/gene="BET3"
/locus_tag="YKR068C"
mRNA complement(570328..570909)
/gene="BET3"
/locus_tag="YKR068C"
/product="TRAPP complex core subunit BET3"
CDS complement(570328..570909)
/gene="BET3"
/locus_tag="YKR068C"
/experiment="EXISTENCE:direct assay:GO:0005085
guanyl-nucleotide exchange factor activity
[PMID:17110339]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0033106 cis-Golgi
network membrane [PMID:9564032]"
/experiment="EXISTENCE:direct assay:GO:1990070 TRAPPI
protein complex [PMID:11239471]"
/experiment="EXISTENCE:direct assay:GO:1990071 TRAPPII
protein complex [PMID:11239471]"
/experiment="EXISTENCE:direct assay:GO:1990072 TRAPPIII
protein complex [PMID:20375281]"
/experiment="EXISTENCE:genetic interaction:GO:0005085
guanyl-nucleotide exchange factor activity
[PMID:11102533|PMID:17041589|PMID:8590804]"
/experiment="EXISTENCE:genetic interaction:GO:0006888
endoplasmic reticulum to Golgi vesicle-mediated transport
[PMID:8590804]"
/experiment="EXISTENCE:genetic interaction:GO:0016236
macroautophagy [PMID:25581738]"
/experiment="EXISTENCE:mutant phenotype:GO:0005085
guanyl-nucleotide exchange factor activity
[PMID:17287728]"
/experiment="EXISTENCE:mutant phenotype:GO:0006888
endoplasmic reticulum to Golgi vesicle-mediated transport
[PMID:11239471|PMID:8590804]"
/experiment="EXISTENCE:mutant phenotype:GO:0006891
intra-Golgi vesicle-mediated transport [PMID:11239471]"
/experiment="EXISTENCE:mutant phenotype:GO:0016236
macroautophagy [PMID:25581738]"
/experiment="EXISTENCE:mutant phenotype:GO:0032258
cytoplasm to vacuole transport by the Cvt pathway
[PMID:25581738]"
/note="Core component of transport protein particle
(TRAPP) complexes I-III; TRAPP complexes are related
multimeric guanine nucleotide-exchange factors for the
GTPase Ypt1, regulating ER-Golgi traffic (TRAPPI),
intra-Golgi traffic (TRAPPII), endosome-Golgi traffic
(TRAPPII and III) and autophagy (TRAPPIII); hydrophilic
homodimeric protein that acts in conjunction with SNARE
proteins in targeting and fusion of ER to Golgi transport
vesicles"
/codon_start=1
/product="TRAPP complex core subunit BET3"
/protein_id="DAA09219.1"
/db_xref="SGD:S000001776"
/translation="MVSTTQSRSLKAMGEEIWKNKTEKINTELFTLTYGSIVAQLCQD
YERDFNKVNDHLYSMGYNIGCRLIEDFLARTALPRCENLVKTSEVLSKCAFKIFLNIT
PNITNWSHNKDTFSLILDENPLADFVELPMDAMKSLWYSNILCGVLKGSLEMVQLDCD
VWFVSDILRGDSQTEIKVKLNRILKDEIPIGED"
gene 571612..573393
/gene="MET1"
/locus_tag="YKR069W"
/gene_synonym="MET20"
mRNA 571612..573393
/gene="MET1"
/locus_tag="YKR069W"
/gene_synonym="MET20"
/product="uroporphyrinogen-III C-methyltransferase"
CDS 571612..573393
/gene="MET1"
/locus_tag="YKR069W"
/gene_synonym="MET20"
/EC_number="2.1.1.107"
/experiment="EXISTENCE:direct assay:GO:0004851
uroporphyrin-III C-methyltransferase activity
[PMID:10051442]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:26928762]"
/experiment="EXISTENCE:mutant phenotype:GO:0019354
siroheme biosynthetic process [PMID:9003798]"
/note="S-adenosyl-L-methionine uroporphyrinogen III
transmethylase; involved in the biosynthesis of siroheme,
a prosthetic group used by sulfite reductase; required for
sulfate assimilation and methionine biosynthesis"
/codon_start=1
/product="uroporphyrinogen-III C-methyltransferase"
/protein_id="DAA09220.1"
/db_xref="SGD:S000001777"
/translation="MVRDLVTLPSSLPLITAGFATDQVHLLIGTGSTDSVSVCKNRIH
SILNAGGNPIVVNPSSPSHTKQLQLEFGKFAKFEIVEREFRLSDLTTLGRVLVCKVVD
RVFVDLPITQSRLCEEIFWQCQKLRIPINTFHKPEFSTFNMIPTWVDPKGSGLQISVT
TNGNGYILANRIKRDIISHLPPNISEVVINMGYLKDRIINEDHKALLEEKYYQTDMSL
PGFGYGLDEDGWESHKFNKLIREFEMTSREQRLKRTRWLSQIMEYYPMNKLSDIKLED
FETSSSPNKKTKQETVTEGVVPPTDENIENGTKQLQLSEVKKEEGPKKLGKISLVGSG
PGSVSMLTIGALQEIKSADIILADKLVPQAILDLIPPKTETFIAKKFPGNAERAQQEL
LAKGLESLDNGLKVVRLKQGDPYIFGRGGEEFNFFKDHGYIPVVLPGISSSLACTVLA
QIPATQRDIADQVLICTGTGRKGALPIIPEFVESRTTVFLMALHRANVLITGLLKHGW
DGDVPAAIVERGSCPDQRVTRTLLKWVPEVVEEIGSRPPGVLVVGKAVNALVEKDLIN
FDESRKFVIDEGFREFEVDVDSLFKLY"
gene 573574..574632
/locus_tag="YKR070W"
mRNA 573574..574632
/locus_tag="YKR070W"
/product="hypothetical protein"
CDS 573574..574632
/locus_tag="YKR070W"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14562095|PMID:16823961|PMID:24769239]"
/note="hypothetical protein; the authentic, non-tagged
protein is detected in highly purified mitochondria in
high-throughput studies"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09221.1"
/db_xref="SGD:S000001778"
/translation="MIGKRFFQTTSKKIAFAFDIDGVLFRGKKPIAGASDALKLLNRN
KIPYILLTNGGGFSERARTEFISSKLDVDVSPLQIIQSHTPYKSLVNKYSRILAVGTP
SVRGVAEGYGFQDVVHQTDIVRYNRDIAPFSGLSDEQVMEYSRDIPDLTTKKFDAVLV
FNDPHDWAADIQIISDAINSENGMLNTLRNEKSGKPSIPIYFSNQDLLWANPYKLNRF
GQGAFRLLVRRLYLELNGEPLQDYTLGKPTKLTYDFAHHVLIDWEKRLSGKIGQSVKQ
KLPLLGTKPSTSPFHAVFMVGDNPASDIIGAQNYGWNSCLVKTGVYNEGDDLKECKPT
LIVNDVFDAVTKTLEKYA"
gene complement(574934..575980)
/gene="DRE2"
/locus_tag="YKR071C"
mRNA complement(574934..575980)
/gene="DRE2"
/locus_tag="YKR071C"
/product="electron carrier DRE2"
CDS complement(574934..575980)
/gene="DRE2"
/locus_tag="YKR071C"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005758
mitochondrial intermembrane space [PMID:18625724]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:18625724]"
/experiment="EXISTENCE:direct assay:GO:0051537 2 iron, 2
sulfur cluster binding [PMID:27166425]"
/experiment="EXISTENCE:direct assay:GO:0051539 4 iron, 4
sulfur cluster binding [PMID:27166425]"
/experiment="EXISTENCE:mutant phenotype:GO:0009055
electron transfer activity [PMID:20802492]"
/experiment="EXISTENCE:mutant phenotype:GO:0016226
iron-sulfur cluster assembly
[PMID:20802492|PMID:18625724]"
/experiment="EXISTENCE:mutant phenotype:GO:0045019
negative regulation of nitric oxide biosynthetic process
[PMID:27178802]"
/experiment="EXISTENCE:mutant phenotype:GO:1901299
negative regulation of hydrogen peroxide-mediated
programmed cell death [PMID:27178802]"
/experiment="EXISTENCE:physical interaction:GO:0005515
protein binding [PMID:27178802]"
/note="Component of the cytosolic Fe-S protein assembly
(CIA) machinery; contains an Fe-S cluster that receives
electrons from NADPH via the action of Tah18p in an early
step in the CIA pathway; ortholog of human Ciapin1;
protein abundance increases in response to DNA replication
stress; inviability of the null mutant is functionally
complemented by human CIAPIN1"
/codon_start=1
/product="electron carrier DRE2"
/protein_id="DAA09222.1"
/db_xref="SGD:S000001779"
/translation="MSQYKTGLLLIHPAVTTTPELVENTKAQAASKKVKFVDQFLINK
LNDGSITLENAKYETVHYLTPEAQTDIKFPKKLISVLADSLKPNGSLIGLSDIYKVDA
LINGFEIINEPDYCWIKMDSSKLNQTVSIPLKKKKTNNTKLQSGSKLPTFKKASSSTS
NLPSFKKADHSRQPIVKETDSFKPPSFKMTTEPKVYRVVDDLIEDSDDDDFSSDSSKA
QYFDQVDTSDDSIEEEELIDEDGSGKSMITMITCGKSKTKKKKACKDCTCGMKEQEEN
EINDIRSQQDKVVKFTEDELTEIDFTIDGKKVGGCGSCSLGDAFRCSGCPYLGLPAFK
PGQPINLDSISDDL"
gene complement(576435..578123)
/gene="SIS2"
/locus_tag="YKR072C"
/gene_synonym="HAL3"
mRNA complement(576435..578123)
/gene="SIS2"
/locus_tag="YKR072C"
/gene_synonym="HAL3"
/product="phosphopantothenoylcysteine decarboxylase
complex subunit SIS2"
CDS complement(576435..578123)
/gene="SIS2"
/locus_tag="YKR072C"
/gene_synonym="HAL3"
/experiment="EXISTENCE:direct assay:GO:0000785 chromatin
[PMID:7705654]"
/experiment="EXISTENCE:direct assay:GO:0004633
phosphopantothenoylcysteine decarboxylase activity
[PMID:19915539]"
/experiment="EXISTENCE:direct assay:GO:0004865 protein
serine/threonine phosphatase inhibitor activity
[PMID:9636153]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:7705654]"
/experiment="EXISTENCE:direct assay:GO:0071513
phosphopantothenoylcysteine decarboxylase complex
[PMID:19915539]"
/experiment="EXISTENCE:direct assay:GO:1990143
CoA-synthesizing protein complex [PMID:23789928]"
/experiment="EXISTENCE:genetic interaction:GO:0007346
regulation of mitotic cell cycle [PMID:10022927]"
/experiment="EXISTENCE:genetic interaction:GO:0015937
coenzyme A biosynthetic process [PMID:19915539]"
/experiment="EXISTENCE:mutant phenotype:GO:0004633
phosphopantothenoylcysteine decarboxylase activity
[PMID:19915539]"
/experiment="EXISTENCE:mutant phenotype:GO:0009651
response to salt stress [PMID:9636153]"
/note="Negative regulatory subunit of protein phosphatase
1 (Ppz1p); involved in coenzyme A biosynthesis; subunit of
the phosphopantothenoylcysteine decarboxylase (PPCDC:
Cab3p, Sis2p, Vhs3p) complex and the CoA-Synthesizing
Protein Complex (CoA-SPC: Cab2p, Cab3p, Cab4p, Cab5p,
Sis2p and Vhs3p); dose-dependent regulator of replicative
lifespan; SIS2 has a paralog, VHS3, that arose from the
whole genome duplication"
/codon_start=1
/product="phosphopantothenoylcysteine decarboxylase
complex subunit SIS2"
/protein_id="DAA09223.1"
/db_xref="SGD:S000001780"
/translation="MTAVASTSGKQDADHNQSIECPRFSRGQKEILLDHEDAKGKDSI
INSPVSGRQSISPTLSNATTTTTKSIMNATGTSGAVVSNTPEPGLKRVPAVTFSDLKQ
QQKQDSLTQLKNDSERTKSPNSNPAPVSNSIPGNHAVIPNHTNTSRTTQLSGSPLVNE
MKDYDPKKKDSALKIVDTMKPDKIMATSTPISRENNKVTAKAPTSITLRKEDAQDQAN
NVSGQINVRSTPEETPVKQSVIPSIIPKRENSKNLDPRLPQDDGKLHVLFGATGSLSV
FKIKPMIKKLEEIYGRDRISIQVILTQSATQFFEQRYTKKIIKSSEKLNKMSQYESTP
ATPVTPTPGQCNMAQVVELPPHIQLWTDQDEWDAWKQRTDPVLHIELRRWADILVVAP
LTANTLSKIALGLCDNLLTSVIRAWNPSYPILLAPSMVSSTFNSMMTKKQLQTIKEEM
SWVTVFKPSEKVMDINGDIGLGGMMDWNEIVNKIVMKLGGYPKNNEEEDDDEDEEEDD
DEEEDTEDKNENNNDDDDDDDDDDDDDDDDDDDDDDDDEDEDEAETPGIIDKHQ"
gene complement(578187..578507)
/locus_tag="YKR073C"
mRNA complement(578187..578507)
/locus_tag="YKR073C"
/product="hypothetical protein"
CDS complement(578187..578507)
/locus_tag="YKR073C"
/note="hypothetical protein; conserved across S.
cerevisiae strains"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA80312.1"
/db_xref="SGD:S000001781"
/translation="MIVFDVSLMIIIIFSFAFNMSQSNILMLYNSPHVLVGSDARNFF
SCKKWHRCFSGEVILEEKKSQSALGSRSLTCTCPLISAVQLHLERSFFSLAFFAVILL
YIPG"
gene 578965..579060
/locus_tag="YNCK0021W"
tRNA join(578965..579001,579025..579060)
/locus_tag="YNCK0021W"
/product="tRNA-Lys"
/experiment="EXISTENCE:curator inference:GO:0005829
cytosol [PMID:9023104]"
/experiment="EXISTENCE:curator inference:GO:0006414
translational elongation [PMID:9023104]"
/note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
analysis; thiolation of uridine at wobble position (34)
requires Ncs6p"
/db_xref="SGD:S000006632"
gene 579209..579676
/gene="AIM29"
/locus_tag="YKR074W"
mRNA 579209..579676
/gene="AIM29"
/locus_tag="YKR074W"
/product="Aim29p"
CDS 579209..579676
/gene="AIM29"
/locus_tag="YKR074W"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276]"
/note="Zpr1p co-chaperone; recognizes eEF1A in GTP-bound,
pre-hydrolysis conformation, dampens folding complex
GTPase activity to drive client release from Zpr1p"
/codon_start=1
/product="Aim29p"
/protein_id="DAA09224.1"
/db_xref="SGD:S000001782"
/translation="MNSTKRLKMSTTFHDYDLEEPLTSNARPLKNSVITIRVIKSFPY
RNVKNIVLHDYDLADKTAKDLFNDVLNKIQNEGSFRPFRNVKFDTLKIYTHAHGSKTV
NLVINFDHDDDWTLDIENDKKKLFEYGIENETEISLFNKEDYLRFKENPEEKW"
gene complement(579827..580750)
/locus_tag="YKR075C"
mRNA complement(579827..580750)
/locus_tag="YKR075C"
/product="hypothetical protein"
CDS complement(579827..580750)
/locus_tag="YKR075C"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276|PMID:14562095]"
/note="hypothetical protein; similar to Reg1p; expression
regulated by glucose and Rgt1p; GFP-fusion protein is
induced in response to the DNA-damaging agent MMS; YKR075C
has a paralog, YOR062C, that arose from the whole genome
duplication"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09225.1"
/db_xref="SGD:S000001783"
/translation="MTSLDDTIISYQNIMLLDNMTNYNKPAIDYFHHEFNDASLEISA
SWTLLLKMRKHKLLRLPSCSSEDVLDYNMYLVRLHHCLWRRWSINHYGLQNSKSNPLS
INWNKETDVTVLYGPDLTNIDSNENEISPVQNQIDQKQTKNLKSALKKNTECWVTEEV
DEINASIESNDNALVKLEDISCPSSVDSHTSSIFDQHSTCTKISSIDEDSEDLMNEKK
EQFPRKLKFNQAVMKREIDSKGTIRESLININDIQHSRHHRRHHRRHHHHHHQNSSHS
DETIKEAHYEFSNYTFGTMEEDIFYRNQVVF"
rep_origin 581833..582070
/note="ARS1118; Autonomously Replicating Sequence"
/db_xref="SGD:S000118408"
gene 582283..583395
/gene="ECM4"
/locus_tag="YKR076W"
/gene_synonym="GTO2"
mRNA 582283..583395
/gene="ECM4"
/locus_tag="YKR076W"
/gene_synonym="GTO2"
/product="S-glutathionyl-(chloro)hydroquinone reductase"
CDS 582283..583395
/gene="ECM4"
/locus_tag="YKR076W"
/gene_synonym="GTO2"
/EC_number="1.8.5.1"
/EC_number="2.5.1.18"
/experiment="EXISTENCE:direct assay:GO:0004364 glutathione
transferase activity
[PMID:16709151|PMID:20388120|PMID:22686328]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095|PMID:16936141]"
/experiment="EXISTENCE:direct assay:GO:0006749 glutathione
metabolic process [PMID:20388120|PMID:22686328]"
/note="S-glutathionyl-(chloro)hydroquinone reductase
(GS-HQR); glutathione transferase involved in cell-surface
biosynthesis and architecture; catalyzes glutathione
(GSH)-dependent reduction of GS-trichloro-p-hydroquinone
to trichloro-p-hydroquinone; expression upregulated upon
exposure to genotoxic agents, such as methyl
methanesulfonate, cisplatin and bleomycin; not an
essential gene; similar to YGR154C; green fluorescent
protein (GFP)-fusion protein localizes to cytoplasm"
/codon_start=1
/product="S-glutathionyl-(chloro)hydroquinone reductase"
/protein_id="DAA09226.1"
/db_xref="SGD:S000001784"
/translation="MSKQWASGTNGAFKRQVSSFRETISKQHPIYKPAKGRYWLYVSL
ACPWAHRTLITRALKGLTSVIGCSVVHWHLDEKGWRFLDMEKQLEDSEDFLEHWHDVA
GGIRTAKEDSSKSFAEIKNDSQRFMVDATNEPHYGYKRISDLYYKSDPQYSARFTVPV
LWDLETQTIVNNESSEIIRILNSSAFDEFVDDDHKKTDLVPAQLKTQIDDFNSWVYDS
INNGVYKTGFAEKAEVYESEVNNVFEHLDKVEKILSDKYSKLKAKYGEEDRQKILGEF
FTVGDQLTEADIRLYTTVIRFDPVYVQHFKCNFTSIRAGYPFIHLWVRNLYWNYDAFR
YTTDFDHIKLHYTRSHTRINPLGITPLGPKPDIRPL"
gene 583653..584744
/gene="MSA2"
/locus_tag="YKR077W"
mRNA 583653..584744
/gene="MSA2"
/locus_tag="YKR077W"
/product="Msa2p"
CDS 583653..584744
/gene="MSA2"
/locus_tag="YKR077W"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:physical interaction:GO:0006357
regulation of transcription by RNA polymerase II
[PMID:18160399]"
/note="Putative transcriptional activator; interacts with
G1-specific transcription factor MBF and G1-specific
promoters; MSA2 has a paralog, MSA1, that arose from the
whole genome duplication"
/codon_start=1
/product="Msa2p"
/protein_id="DAA09227.1"
/db_xref="SGD:S000001785"
/translation="MVYTTPQQQQRFSSTPQSSHTLIFSPIRAPSMQTPSSLDYQSPS
IVVSSSSMKVHGRSSSFGKFSLSIGQNGKATILGPINVLPTDTSKMEKPVPKKKPVTS
DRVEKTRILSLLKKMRNKSSTVNKKYSKVPLKSTTSLQPAATAPSPLVSNIIKPSPKK
LASPRTPNANSNLNLNFTSFQIKTGFTPNLDGILLENFTSPNTTADSQGNSASNIINN
NHGSANNTNQFLFNLPLQSSPRQFRSPARLIDPLPISDWNTSLLMSPPRTTNFESANN
HFNSNFAQASMLRRPSLPHIDEVIPQDSNPANYSDRSDYLSVDQNANNHNGALSEQTY
NNIMKSSMISLPIEKDDATMALRKLVSRE"
gene 584952..586709
/gene="VPS501"
/locus_tag="YKR078W"
/gene_synonym="VIN1"
mRNA 584952..586709
/gene="VPS501"
/locus_tag="YKR078W"
/gene_synonym="VIN1"
/product="sorting nexin family protein"
CDS 584952..586709
/gene="VPS501"
/locus_tag="YKR078W"
/gene_synonym="VIN1"
/experiment="EXISTENCE:direct assay:GO:0001786
phosphatidylserine binding [PMID:35098628]"
/experiment="EXISTENCE:direct assay:GO:0005515 protein
binding [PMID:35098628]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005774 vacuolar
membrane [PMID:35098628]"
/experiment="EXISTENCE:direct assay:GO:0032266
phosphatidylinositol-3-phosphate binding
[PMID:35098628|PMID:11557775]"
/experiment="EXISTENCE:mutant phenotype:GO:1903432
regulation of TORC1 signaling [PMID:35098628]"
/note="Vacuolar SNX-BAR protein, regulates TORC1 signaling
during autophagy induction; binds
phosphatidylinositol-3-phosphate; vacuolar localization of
Vps501p is dependent upon direct interaction with Iml1p
and a unique lipid binding specificity that is also
required for its function; VPS501 has paralog VPS5 that
arose from the whole genome duplication"
/codon_start=1
/product="sorting nexin family protein"
/protein_id="DAA09228.1"
/db_xref="SGD:S000001786"
/translation="MENDKASHASPSIGVNEFVVQGEISIDDSERSVKSVSVSISDDE
DSKTDVQDNMATPSTRSKFQTDLAIDNRLLEKDPKYKKLFTEKRRRRRPESCINLMTK
GKGTGQKDNINDQIFSLRILPGSDLNSLKDSLWIIKISTQPDVEKTIARAFSDFYWLY
HQLQNNHWGKTIPPPTRSNILVEKDEFAINHLFMIRNNEKYDPIFNFKPEYIISLQLM
AMIKHIFNDKVLRLDSNFIDFISWDDDLPESLQIVVDDSTFTGDKILMTSSQFRELKE
FHKQSKKVESITNSHASLIPVTELTEIYISPTKLFSRKDYQRLFQPQSTDNTFNNNDP
LIQEWIPKSKTLFTSLSFGSSAPTYQEASTEIQACHDWVSISKEQWKQLLYHVLQYIV
DEAVKVNSVINEFTECLKQISLDEVIRANSELFLKFSKLNESFLKKFKGASRQDILKL
IILFDENVRFCESFESILNQRLKLGKILSIIEVDLDKKKNFLDKLSPGNNNSNNEDLK
IRTAEDEYRIVLKRYNRVKQSWEKIMEDILNERKEFEKREAAEVNSCLKSIRDLNMDE
KKHYLQLWQDFVPDEHISQ"
gene complement(586789..589305)
/gene="TRZ1"
/locus_tag="YKR079C"
mRNA complement(586789..589305)
/gene="TRZ1"
/locus_tag="YKR079C"
/product="tRNase Z"
CDS complement(586789..589305)
/gene="TRZ1"
/locus_tag="YKR079C"
/EC_number="3.1.26.11"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095|PMID:24249226]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14690591|PMID:24249226|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0042780 tRNA 3'-end
processing [PMID:24249226|PMID:12711671]"
/experiment="EXISTENCE:direct assay:GO:0042781 3'-tRNA
processing endoribonuclease activity
[PMID:12711671|PMID:24249226]"
/experiment="EXISTENCE:direct assay:GO:1990180
mitochondrial tRNA 3'-end processing [PMID:24249226]"
/experiment="EXISTENCE:mutant phenotype:GO:0042780 tRNA
3'-end processing [PMID:24249226]"
/experiment="EXISTENCE:mutant phenotype:GO:1990180
mitochondrial tRNA 3'-end processing [PMID:24249226]"
/note="tRNA 3'-end processing endonuclease tRNase Z; also
localized to mitochondria and interacts genetically with
Rex2 exonuclease; homolog of the human candidate prostate
cancer susceptibility gene ELAC2"
/codon_start=1
/product="tRNase Z"
/protein_id="DAA09229.1"
/db_xref="SGD:S000001787"
/translation="MFTFIPITHPTSDTKHPLLLVQSAHGEKYFFGKIGEGSQRSLTE
NKIRISKLKDIFLTGELNWSDIGGLPGMILTIADQGKSNLVLHYGNDILNYIVSTWRY
FVFRFGIDLNDHIMKDKEVYKDKIIAVKSFNVLKNGGEDRLGVFDSFQKGVLRSIVAK
MFPKHAPTDRYDPSSDPHLNVELPDLDAKVEVSTNYEISFSPVRGKFKVEEAIKLGVP
KGPLFAKLTKGQTITLDNGIVVTPEQVLENERHFAKVLILDIPDDLYLNAFVEKFKDY
DCAELGMVYYFLGDEVTINDNLFAFIDIFEKNNYGKVNHMISHNKISPNTISFFGSAL
TTLKLKALQVNNYNLPKTDRVFSKDFYDRFDTPLSRGTSMCKSQEEPLNTIIEKDNIH
IFSQNKTVTFEPFRMNEEPMKCNINGEVADFSWQEIFEEHVKPLEFPLADVDTVINNQ
LHVDNFNNSAEKKKHVEIITLGTGSALPSKYRNVVSTLVKVPFTDADGNTINRNIMLD
AGENTLGTIHRMFSQLAVKSIFQDLKMIYLSHLHADHHLGIISVLNEWYKYNKDDETS
YIYVVTPWQYHKFVNEWLVLENKEILKRIKYISCEHFINDSFVRMQTQSVPLAEFNEI
LKENSNQESNRKLELDRDSSYRDVDLIRQMYEDLSIEYFQTCRAIHCDWAYSNSITFR
MDENNEHNTFKVSYSGDTRPNIEKFSLEIGYNSDLLIHEATLENQLLEDAVKKKHCTI
NEAIGVSNKMNARKLILTHFSQRYPKLPQLDNNIDVMAREFCFAFDSMIVDYEKIGEQ
QRIFPLLNKAFVEEKEEEEDVDDVESVQDLEVKLKKHKKN"
gene 590395..591357
/gene="MTD1"
/locus_tag="YKR080W"
mRNA 590395..591357
/gene="MTD1"
/locus_tag="YKR080W"
/product="methylenetetrahydrofolate dehydrogenase
(NAD(+))"
CDS 590395..591357
/gene="MTD1"
/locus_tag="YKR080W"
/EC_number="1.5.1.15"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:8608153]"
/experiment="EXISTENCE:direct assay:GO:0006730 one-carbon
metabolic process [PMID:8608153]"
/experiment="EXISTENCE:direct assay:GO:0009113 purine
nucleobase biosynthetic process [PMID:8608153]"
/experiment="EXISTENCE:mutant phenotype:GO:0004487
methylenetetrahydrofolate dehydrogenase (NAD+) activity
[PMID:8416923]"
/experiment="EXISTENCE:mutant phenotype:GO:0006730
one-carbon metabolic process [PMID:8608153]"
/experiment="EXISTENCE:mutant phenotype:GO:0009113 purine
nucleobase biosynthetic process [PMID:8608153]"
/experiment="EXISTENCE:mutant phenotype:GO:0009396 folic
acid-containing compound biosynthetic process
[PMID:8608153]"
/note="NAD-dependent 5,10-methylenetetrahydrafolate
dehydrogenase; plays a catalytic role in oxidation of
cytoplasmic one-carbon units; expression is regulated by
Bas1p and Bas2p, repressed by adenine, and may be induced
by inositol and choline"
/codon_start=1
/product="methylenetetrahydrofolate dehydrogenase
(NAD(+))"
/protein_id="DAA09230.1"
/db_xref="SGD:S000001788"
/translation="MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLA
NNDPAAKMYATWTQKTSESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVF
GNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILE
FLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRG
ESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFAC
TKNFSDDVKEKASLYVPMTGKVTIAMLLRNMLRLVRNVELSKEK"
gene complement(591506..592540)
/gene="RPF2"
/locus_tag="YKR081C"
mRNA complement(591506..592540)
/gene="RPF2"
/locus_tag="YKR081C"
/product="rRNA-binding ribosome biosynthesis protein RPF2"
CDS complement(591506..592540)
/gene="RPF2"
/locus_tag="YKR081C"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:11864606]"
/experiment="EXISTENCE:direct assay:GO:0008097 5S rRNA
binding [PMID:25855814|PMID:11864606]"
/experiment="EXISTENCE:direct assay:GO:0008312 7S RNA
binding [PMID:11864606]"
/experiment="EXISTENCE:direct assay:GO:0019843 rRNA
binding [PMID:11864606]"
/experiment="EXISTENCE:direct assay:GO:0030687
preribosome, large subunit precursor [PMID:17443350]"
/experiment="EXISTENCE:mutant phenotype:GO:0000027
ribosomal large subunit assembly [PMID:11864606]"
/experiment="EXISTENCE:mutant phenotype:GO:0000463
maturation of LSU-rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:11864606]"
/experiment="EXISTENCE:mutant phenotype:GO:0000466
maturation of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:11864606]"
/experiment="EXISTENCE:mutant phenotype:GO:0008097 5S rRNA
binding [PMID:25855814]"
/experiment="EXISTENCE:mutant phenotype:GO:1902626
assembly of large subunit precursor of preribosome
[PMID:22735702]"
/note="Essential protein involved in rRNA maturation and
ribosomal assembly; involved in the processing of pre-rRNA
and the assembly of the 60S ribosomal subunit; interacts
with ribosomal protein L11; localizes predominantly to the
nucleolus; constituent of 66S pre-ribosomal particles"
/codon_start=1
/product="rRNA-binding ribosome biosynthesis protein RPF2"
/protein_id="DAA09231.1"
/db_xref="SGD:S000001789"
/translation="MIRTVKPKNARAKRALVKREAKLVENVKQALFIPGQSCNKNLHD
IMVDLSALKKPDMKRFNRKNDIHPFEDMSPLEFFSEKNDCSLMVLMTSSKKRKNNMTF
IRTFGYKIYDMIELMVADNFKLLSDFKKLTFTVGLKPMFTFQGAAFDTHPVYKQIKSL
FLDFFRGESTDLQDVAGLQHVISMTIQGDFQDGEPLPNVLFRVYKLKSYKSDQGGKRL
PRIELVEIGPRLDFKIGRIHTPSPDMVTEAHKKPKQLEMKTKKNVELDIMGDKLGRIH
MGKQDLGKLQTRKMKGLKSKFDQGTEEGDGEVDEDYEDEASYSDDGQEYEEEFVSATD
IEPSAKRQKK"
gene 592825..596298
/gene="NUP133"
/locus_tag="YKR082W"
/gene_synonym="RAT3"
mRNA 592825..596298
/gene="NUP133"
/locus_tag="YKR082W"
/gene_synonym="RAT3"
/product="Nup133p"
CDS 592825..596298
/gene="NUP133"
/locus_tag="YKR082W"
/gene_synonym="RAT3"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:22932476]"
/experiment="EXISTENCE:direct assay:GO:0005643 nuclear
pore [PMID:10684247]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:22932476]"
/experiment="EXISTENCE:direct assay:GO:0030466 silent
mating-type cassette heterochromatin formation
[PMID:21818277]"
/experiment="EXISTENCE:direct assay:GO:0031080 nuclear
pore outer ring [PMID:18046406|PMID:11823431]"
/experiment="EXISTENCE:direct assay:GO:0045893 positive
regulation of DNA-templated transcription [PMID:15817685]"
/experiment="EXISTENCE:genetic interaction:GO:0006302
double-strand break repair [PMID:15725626]"
/experiment="EXISTENCE:genetic interaction:GO:0045893
positive regulation of DNA-templated transcription
[PMID:15817685]"
/experiment="EXISTENCE:mutant phenotype:GO:0000122
negative regulation of transcription by RNA polymerase II
[PMID:22110603]"
/experiment="EXISTENCE:mutant phenotype:GO:0000973
post-transcriptional tethering of RNA polymerase II gene
DNA at nuclear periphery [PMID:20932479]"
/experiment="EXISTENCE:mutant phenotype:GO:0006302
double-strand break repair [PMID:16418532|PMID:17538013]"
/experiment="EXISTENCE:mutant phenotype:GO:0006409 tRNA
export from nucleus [PMID:8524308]"
/experiment="EXISTENCE:mutant phenotype:GO:0006606 protein
import into nucleus [PMID:12730220]"
/experiment="EXISTENCE:mutant phenotype:GO:0016973
poly(A)+ mRNA export from nucleus
[PMID:7813444|PMID:21036941]"
/experiment="EXISTENCE:mutant phenotype:GO:0017056
structural constituent of nuclear pore [PMID:22331846]"
/experiment="EXISTENCE:mutant phenotype:GO:0031509
subtelomeric heterochromatin formation [PMID:16418532]"
/experiment="EXISTENCE:mutant phenotype:GO:0031990 mRNA
export from nucleus in response to heat stress
[PMID:18258809]"
/experiment="EXISTENCE:mutant phenotype:GO:0034398
telomere tethering at nuclear periphery [PMID:16418532]"
/experiment="EXISTENCE:mutant phenotype:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:22110603]"
/experiment="EXISTENCE:mutant phenotype:GO:0051664 nuclear
pore localization
[PMID:22331846|PMID:7813444|PMID:7862658|PMID:9725905]"
/note="Subunit of Nup84p subcomplex of nuclear pore
complex (NPC); contributes to nucleocytoplasmic transport,
NPC biogenesis; is involved in establishment of a normal
nucleocytoplasmic concentration gradient of GTPase Gsp1p;
also plays roles in several processes that may require
localization of genes or chromosomes at nuclear periphery,
including double-strand break repair, transcription and
chromatin silencing; relocalizes to cytosol in response to
hypoxia; homolog of human NUP133"
/codon_start=1
/product="Nup133p"
/protein_id="DAA09232.1"
/db_xref="SGD:S000001790"
/translation="MSEKKVHLRLRKELSVPIAVVENESLAQLSYEEESQASLMDISM
EQQQLRLHSHFDNSKVFTENNRYIVKTLQTDYSSGFSNDDELNGYIDMQIGYGLVNDH
KKVYIWNIHSTQKDTPYITVPFRSDDNDEIAVAPRCILTFPATMDESPLALNPNDQDE
TGGLIIIKGSKAIYYEDINSINNLNFKLSEKFSHELELPINSSGGEKCDLMLNCEPAG
IVLSTNMGRIFFITIRNSMGKPQLKLGKLLNKPFKLGIWSKIFNTNSSVVSLRNGPIL
GKGTRLVYITTNKGIFQTWQLSATNSHPTKLIDVNIYEAILESLQDLYPFAHGTLKIW
DSHPLQDESSQLFLSSIYDSSCNETYYILSTIIFDSSSNSFTIFSTYRLNTFMESITD
TKFKPKIFIPQMENANDTNEVTSILVMFPNAVVITQVNSKLDSSYSMRRKWEDIVSLR
NDIDIIGSGYDSKSLYVLTKQMGVLQFFVKENEETNSKPEVGFVKSHVDQAVYFSKIN
ANPIDFNLPPEISLDQESIEHDLKLTSEEIFHSNGKYIPPMLNTLGQHLSVRKEFFQN
FLTFVAKNFNYKISPELKLDLIEKFEILNCCIKFNSIIRQSDVLNDIWEKTLSNYNLT
QNEHLTTKTVVINSPDVFPVIFKQFLNHVVFVLFPSQNQNFKLNVTNLINLCFYDGIL
EEGEKTIRYELLELDPMEVDTSKLPWFINFDYLNCINQCFFDFTFACEEEGSLDSYKE
GLLKIVKILYYQFNQFKIWINTQPVKSVNANDNFININNLYDDNHLDWNHVLCKVNLK
EQCIQIAEFYKDLSGLVQTLQTLDQNDSTTVSLYETFFNEFPKEFSFTLFEYLIKHKK
LNDLIFRFPQQHDVLIQFFQESAPKYGHVAWIQQILDGSYADAMNTLKNITVDDSKKG
ESLSECELHLNVAKLSSLLVEKDNLDINTLRKIQYNLDTIDAEKNISNKLKKGEVQIC
KRFKNGSIREVFNILVEELKSTTVVNLSDLVELYSMLDDEESLFIPLRLLSVDGNLLN
FEVKKFLNALVWRRIVLLNASNEGDKLLQHIVKRVFDEELPKNNDFPLPSVDLLCDKS
LLTPEYISETYGRFPIDQNAIREEIYEEISQVETLNSDNSLEIKLHSTIGSVAKEKNY
TINYETNTVEY"
gene complement(596421..596822)
/gene="DAD2"
/locus_tag="YKR083C"
/gene_synonym="HSK1"
mRNA complement(596421..596822)
/gene="DAD2"
/locus_tag="YKR083C"
/gene_synonym="HSK1"
/product="Dad2p"
CDS complement(596421..596822)
/gene="DAD2"
/locus_tag="YKR083C"
/gene_synonym="HSK1"
/experiment="EXISTENCE:direct assay:GO:0008017 microtubule
binding [PMID:15664196|PMID:16777964]"
/experiment="EXISTENCE:direct assay:GO:0008608 attachment
of spindle microtubules to kinetochore [PMID:17620411]"
/experiment="EXISTENCE:direct assay:GO:0031116 positive
regulation of microtubule polymerization [PMID:15664196]"
/experiment="EXISTENCE:direct assay:GO:0042729 DASH
complex [PMID:15640796|PMID:15664196]"
/experiment="EXISTENCE:direct assay:GO:0051010 microtubule
plus-end binding [PMID:17620411|PMID:20479465]"
/experiment="EXISTENCE:direct assay:GO:0051987 positive
regulation of attachment of spindle microtubules to
kinetochore [PMID:20479465|PMID:20479468]"
/note="Essential subunit of the Dam1 complex (aka DASH
complex); complex couples kinetochores to the force
produced by MT depolymerization thereby aiding in
chromosome segregation; is transferred to the kinetochore
prior to mitosis"
/codon_start=1
/product="Dad2p"
/protein_id="DAA09233.1"
/db_xref="SGD:S000001791"
/translation="MDSIDEQIAIKRKELQSLQKITSLTDGLKIQLTELNEQIKEMGM
NADSVAQLMNNWDSIINNISQASLGLLQYAEGDYEIGPWKDSKKKESEQSNETGLEAQ
ENDKNDEDNDEDEDLVPLPETMVRIRVDGNE"
gene complement(597055..598890)
/gene="HBS1"
/locus_tag="YKR084C"
mRNA complement(597055..598890)
/gene="HBS1"
/locus_tag="YKR084C"
/product="ribosome dissociation factor GTPase HBS1"
CDS complement(597055..598890)
/gene="HBS1"
/locus_tag="YKR084C"
/experiment="EXISTENCE:direct assay:GO:0003924 GTPase
activity [PMID:20947765]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0032790 ribosome
disassembly [PMID:20947765]"
/experiment="EXISTENCE:direct assay:GO:0043022 ribosome
binding [PMID:21623367]"
/experiment="EXISTENCE:direct assay:GO:1990533 Dom34-Hbs1
complex [PMID:21623367]"
/experiment="EXISTENCE:genetic interaction:GO:0070966
nuclear-transcribed mRNA catabolic process, no-go decay
[PMID:16554824]"
/experiment="EXISTENCE:mutant phenotype:GO:0045727
positive regulation of translation [PMID:24424461]"
/experiment="EXISTENCE:mutant phenotype:GO:0070651
nonfunctional rRNA decay [PMID:19481524]"
/note="GTPase with similarity to translation release
factors; together with binding partner Dom34p, facilitates
ribosomal subunit dissociation and peptidyl-tRNA release
when translation is stalled, particularly in 3' UTRs;
genetically implicated in mRNA no-go decay; HBS1 has a
paralog, SKI7, that arose from the whole genome
duplication"
/codon_start=1
/product="ribosome dissociation factor GTPase HBS1"
/protein_id="DAA09234.1"
/db_xref="SGD:S000001792"
/translation="MAYSDYSDGADDMPDFHDEGEFDDYLNDDEYDLMNEVFPTLKAQ
LQDYQGWDNLSLKLALFDNNFDLESTLAELKKTLKKKKTPKKPIAAANGSANVTQKLA
NISISQQRPNDRLPDWLDEEESEGERNGEEANDEKTVQRYYKTTVPTKPKKPHDISAF
VKSALPHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAW
IMDQTNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCV
DCSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLP
YLVDIGFFEDNINWVPISGFSGEGVYKIEYTDEVRQWYNGPNLMSTLENAAFKISKEN
EGINKDDPFLFSVLEIIPSKKTSNDLALVSGKLESGSIQPGESLTIYPSEQSCIVDKI
QVGSQQGQSTNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVL
ELTTFDMNRPLLPGTPFILFIGVKEQPARIKRLISFIDKGNTASKKKIRHLGSKQRAF
VEIELIEVKRWIPLLTAHENDRLGRVVLRKDGRTIAAGKISEITQ"
gene complement(599094..599681)
/gene="MRPL20"
/locus_tag="YKR085C"
/gene_synonym="mL58"
mRNA complement(599094..599681)
/gene="MRPL20"
/locus_tag="YKR085C"
/gene_synonym="mL58"
/product="mitochondrial 54S ribosomal protein YmL20"
CDS complement(599094..599681)
/gene="MRPL20"
/locus_tag="YKR085C"
/gene_synonym="mL58"
/experiment="EXISTENCE:curator inference:GO:0032543
mitochondrial translation [PMID:12392552]"
/experiment="EXISTENCE:direct assay:GO:0003735 structural
constituent of ribosome [PMID:12392552]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005762
mitochondrial large ribosomal subunit [PMID:12392552]"
/note="Mitochondrial ribosomal protein of the large
subunit"
/codon_start=1
/product="mitochondrial 54S ribosomal protein YmL20"
/protein_id="DAA09235.1"
/db_xref="SGD:S000001793"
/translation="MIGRGVCCRSFHTAGSAWKQFGFPKTQVTTIYNKTKSASNYKGY
LKHRDAPGMYYQPSESIATGSVNSETIPRSFMAASDPRRGLDMPVQSTKAKQCPNVLV
GKSTVNGKTYHLGPQEIDEIRKLRLDNPQKYTRKFLAAKYGISPLFVSMVSKPSEQHV
QIMESRLQEIQSRWKEKRRIAREDRKRRKLLWYQA"
gene 599857..603072
/gene="PRP16"
/locus_tag="YKR086W"
/gene_synonym="PRP23"
/gene_synonym="RNA16"
mRNA 599857..603072
/gene="PRP16"
/locus_tag="YKR086W"
/gene_synonym="PRP23"
/gene_synonym="RNA16"
/product="DEAH-box RNA helicase PRP16"
CDS 599857..603072
/gene="PRP16"
/locus_tag="YKR086W"
/gene_synonym="PRP23"
/gene_synonym="RNA16"
/EC_number="3.6.4.13"
/experiment="EXISTENCE:direct assay:GO:0000378 RNA exon
ligation [PMID:23685439]"
/experiment="EXISTENCE:direct assay:GO:0008186
ATP-dependent activity, acting on RNA [PMID:1825134]"
/experiment="EXISTENCE:direct assay:GO:0071007 U2-type
catalytic step 2 spliceosome [PMID:1825134]"
/experiment="EXISTENCE:mutant phenotype:GO:0000350
generation of catalytic spliceosome for second
transesterification step [PMID:16103217|PMID:1825134]"
/experiment="EXISTENCE:mutant phenotype:GO:0000386 second
spliceosomal transesterification activity [PMID:1825134]"
/experiment="EXISTENCE:mutant phenotype:GO:0016073 snRNA
metabolic process [PMID:19458033]"
/experiment="EXISTENCE:mutant phenotype:GO:0040031 snRNA
modification [PMID:19458033]"
/note="DEAH-box RNA helicase; involved in the second
catalytic step of splicing and in exon ligation; exhibits
ATP-dependent RNA unwinding activity; mediates the release
of Yju2p and Cwc25p in the second step; in the absence of
ATP, stabilizes the binding of Cwc25p to the spliceosome
in the first catalytic step; missense mutation in human
ortholog DHX38 associated with early-onset retinitis
pigmentosa"
/codon_start=1
/product="DEAH-box RNA helicase PRP16"
/protein_id="DAA09236.1"
/db_xref="SGD:S000001794"
/translation="MGHSGREERIKDIFKELTSKELTPGLLLTLQKLAQKPNTNLEQF
IASCKALTKLSSNNPIIFNELLELLKNKSEEDSTGPKKIAPSINKRKKFKIQLDLDDN
EDELDSPVQKKPAPTRTLFKRIDKLKAKQLRQYSPTVKDPSPNSEQQTQNGHAETKDY
EPTRSEVVEEDREWYDNDDDYGNLVPEPLSELPEEAKLLPVIRNIDNDDALRNTVQLY
PIPLKQRMEWIPPFLSKFALENKVPTSIIIGSISETSSQVSALSMVNPFRNPDSEFSA
NAKRGSKLVALRRINMEHIQQSRDNTTVLNTAMGEVLGLENNNKAKDKSNQKICDDTA
LFTPSKDDIKHTKEQLPVFRCRSQLLSLIRENQVVVIIGETGSGKTTQLAQYLYEEGY
ANDRGKSIVVTQPRRVAAISVAKRVAMEMQVPLGKEVGYSIRFEDVTDSECTKLKFVT
DGILLRETLLDDTLDKYSCVIIDEAHERSLNTDILLGFFKILLARRRDLKLIITSATM
NAKKFSAFFGNAPQFTIPGRTFPVQTIYTSNPVQDYVEAAVSQAVKIHLANDCSSGDI
LIFMTGQEDIETTFDTLQEKFLQVYSKKFGTANFEEINDIEILPIYSALPADLQFKIF
QDLHGTKRKIIIATNIAETSLTIKGIRYVIDCGYSKLKVYNPKIGLDSLVITPISKAN
ADQRSGRAGRTAPGTAYRLYTEDTFKEDMYLQTIPEIQRTNLSNTLLLLKSLDVTDEL
SKFPFIDKPPLQTFLSSLYELWFIGAIDTSGQLTPLGLQMAKFPLQPSLSKILLIAVR
NGCSDEMLTIVSMLSVPQVFYRPKERQKEADIARNKFFIAKSDHLTLLNVFEQWRANN
FSSHWCNKHFVQYKSLVRARDIRDQLLTILKSQKIPVISSGKDWDIIKKCICSGFAHQ
AAKITGLRNYVHLKTGVSVQLHPTSALHGLGDLPPYVVYHELLMTSKEYICCVTSVDP
FWLMEYGGLLYDIKRIKNDQEATTTGLFGEHYEHTLDKVEDDIDINIRRCKDMRDSVI
QELKMTDNSNKEDKKQKTKKQNILNGKENSMKPFKRRKPFF"
gene complement(603195..604232)
/gene="OMA1"
/locus_tag="YKR087C"
mRNA complement(603195..604232)
/gene="OMA1"
/locus_tag="YKR087C"
/product="metalloendopeptidase"
CDS complement(603195..604232)
/gene="OMA1"
/locus_tag="YKR087C"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14562095|PMID:24769239]"
/experiment="EXISTENCE:direct assay:GO:0005743
mitochondrial inner membrane [PMID:12963738]"
/experiment="EXISTENCE:mutant phenotype:GO:0004222
metalloendopeptidase activity [PMID:12963738]"
/experiment="EXISTENCE:mutant phenotype:GO:0006515 protein
quality control for misfolded or incompletely synthesized
proteins [PMID:12963738]"
/experiment="EXISTENCE:mutant phenotype:GO:0031929 TOR
signaling [PMID:27325672]"
/experiment="EXISTENCE:mutant phenotype:GO:0035694
mitochondrial protein catabolic process [PMID:27325672]"
/note="Metalloendopeptidase of the mitochondrial inner
membrane; important for adaptive responses to various
homeostatic insults, preservation of normal mitochondrial
function under damage-eliciting conditions, and stability
of respiratory supercomplexes; involved in turnover of
membrane-embedded proteins; mediates degradation of Cox1p
in coa2 mutant cells; zebrafish ortholog has a role in
organ development and mouse ortholog is also required for
respiratory supercomplex stability"
/codon_start=1
/product="metalloendopeptidase"
/protein_id="DAA09237.1"
/db_xref="SGD:S000001795"
/translation="MLRNIIRFKGFGKGTSGGFLKPVSFRVQLTRCYRYDNGPSYRRF
NNGEYSQKSSFKSILLDKSSRKYLALLFGGCSLFYYTHLDKAPVSDRSRFIWVSRPLE
LTIGNYTYKSIWRQTQQEILPPQHPLSIKIENIFMKIVEAAYKDPSVDNSLLDGIKWE
IHVVNDPTASPNAFVLPGGKVFIFSSILPICANDDGIATVLAHEFAHQLARHTAENLS
KAPIYSLLGLVLYTVTGAHAINNILLDGFLRMPASRQMETEADYIGLMIMSRACFQPQ
ESIKVWERMANFEKQMNRGGVVNMEFLSTHPASTRRIENMSKWLPKANEIYEQSDCSS
MGNYYKSFFSM"
gene complement(604405..605418)
/gene="TVP38"
/locus_tag="YKR088C"
mRNA complement(604405..605418)
/gene="TVP38"
/locus_tag="YKR088C"
/product="Tvp38p"
CDS complement(604405..605418)
/gene="TVP38"
/locus_tag="YKR088C"
/experiment="EXISTENCE:direct assay:GO:0000139 Golgi
membrane [PMID:16107716]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:genetic interaction:GO:0016192
vesicle-mediated transport [PMID:17178117]"
/experiment="EXISTENCE:mutant phenotype:GO:0000022 mitotic
spindle elongation [PMID:18194531]"
/note="Integral membrane protein; localized to late Golgi
vesicles along with the v-SNARE Tlg2p; required for
asymmetric localization of Kar9p during mitosis;
GFP-fusion protein localizes to the cytoplasm in a
punctate pattern"
/codon_start=1
/product="Tvp38p"
/protein_id="DAA09238.1"
/db_xref="SGD:S000001796"
/translation="MSQSYEAGNANMGQGEDDEFDGYFEDFDNDIMPNSNNGQRVGTN
AGLSFNDEVNVNDDDFLDIYNMSPRERLMHNIRKNVQKLQFYFYSLRLWQQIIIVLLG
IMLMIMGILLLVFHNAILHKVVVTSNDLREKMSTHFILMVLIFFVAFPPMIGYSLLST
TTGLIYGVSFEGWVTLALGSVTGSIASFVVFKTILHSRAEKLVHLNRRFEALASILQE
NNSYWILALLRLCPFPYSLTNGAIAGVYGISVRNFSIANIITTPKLFIYLFIGSRVKS
LAESESTGSRVFDLVSIIITLLILSLTAWLLYFKTKKRYLELQNRDRQVSTDQLPELS
FEV"
gene complement(605633..608365)
/gene="TGL4"
/locus_tag="YKR089C"
/gene_synonym="STC1"
mRNA complement(605633..608365)
/gene="TGL4"
/locus_tag="YKR089C"
/gene_synonym="STC1"
/product="triacylglycerol lipase"
CDS complement(605633..608365)
/gene="TGL4"
/locus_tag="YKR089C"
/gene_synonym="STC1"
/EC_number="3.1.1.3"
/experiment="EXISTENCE:direct assay:GO:0004771 sterol
esterase activity [PMID:20332534]"
/experiment="EXISTENCE:direct assay:GO:0004806
triglyceride lipase activity
[PMID:16135509|PMID:20332534]"
/experiment="EXISTENCE:direct assay:GO:0005811 lipid
droplet
[PMID:14562095|PMID:16135509|PMID:16267052|PMID:24390141|P
MID:24868093]"
/experiment="EXISTENCE:direct assay:GO:0006642
triglyceride mobilization [PMID:16135509]"
/experiment="EXISTENCE:direct assay:GO:0042171
lysophosphatidic acid acyltransferase activity
[PMID:20332534]"
/experiment="EXISTENCE:direct assay:GO:0047499
calcium-independent phospholipase A2 activity
[PMID:20332534]"
/experiment="EXISTENCE:genetic interaction:GO:0007114 cell
budding [PMID:19150427]"
/experiment="EXISTENCE:genetic interaction:GO:0019433
triglyceride catabolic process [PMID:16267052]"
/experiment="EXISTENCE:mutant phenotype:GO:0004771 sterol
esterase activity [PMID:20332534]"
/experiment="EXISTENCE:mutant phenotype:GO:0004806
triglyceride lipase activity
[PMID:16135509|PMID:20332534]"
/experiment="EXISTENCE:mutant phenotype:GO:0006642
triglyceride mobilization [PMID:16135509]"
/experiment="EXISTENCE:mutant phenotype:GO:0006644
phospholipid metabolic process [PMID:20332534]"
/experiment="EXISTENCE:mutant phenotype:GO:0007114 cell
budding [PMID:19150427]"
/experiment="EXISTENCE:mutant phenotype:GO:0019433
triglyceride catabolic process [PMID:16267052]"
/experiment="EXISTENCE:mutant phenotype:GO:0047499
calcium-independent phospholipase A2 activity
[PMID:20332534]"
/note="Multifunctional lipase/hydrolase/phospholipase;
triacylglycerol lipase, steryl ester hydrolase, and
Ca2+-independent phospholipase A2; catalyzes acyl-CoA
dependent acylation of LPA to PA; required with Tgl3p for
timely bud formation; phosphorylated and activated by
Cdc28p; TGL4 has a paralog, TGL5, that arose from the
whole genome duplication"
/codon_start=1
/product="triacylglycerol lipase"
/protein_id="DAA09239.1"
/db_xref="SGD:S000001797"
/translation="MSSKISDLTSTQNKPLLVTQQLIEKYYEQILGTSQNIIPILNPK
NKFIRPSKDNSDVERVEEDAGKRLQTGKNKTTNKVNFNLDTGNEDKLDDDQETVTENE
NNDIEMVETDEGEDERQGSSLASKCKSFLYNVFVGNYERDILIDKVCSQKQHAMSFEE
WCSAGARLDDLTGKTEWKQKLESPLYDYKLIKDLTSRMREERLNRNYAQLLYIIRTNW
VRNLGNMGNVNLYRHSHVGTKYLIDEYMMESRLALESLMESDLDDSYLLGILQQTRRN
IGRTALVLSGGGTFGLFHIGVLGTLFELDLLPRVISGSSAGAIVASILSVHHKEEIPV
LLNHILDKEFNIFKDDKQKSESENLLIKISRFFKNGTWFDNKHLVNTMIEFLGDLTFR
EAYNRTGKILNITVSPASLFEQPRLLNNLTAPNVLIWSAVCASCSLPGIFPSSPLYEK
DPKTGERKPWTGSSSVKFVDGSVDNDLPISRLSEMFNVDHIIACQVNIHVFPFLKLSL
SCVGGEIEDEFSARLKQNLSSIYNFMANEAIHILEIGSEMGIAKNALTKLRSVLSQQY
SGDITILPDMCMLFRIKELLSNPTKEFLLREITNGAKATWPKVSIIQNHCGQEFALDK
AISYIKGRMIVTSSLKTPFQFADSVIGLIKAPEQTSDESKNPENSTLLTRTPTKGDNH
ISNVLDDNLLESESTNSLLLLRENASTYGRSPSGFRPRYSITSASLNPRHQRRKSDTI
STSRRPAKSFSFSVASPTSRMLRQSSKINGHPPPILQKKTSMGRLMFPMDAKTYDPES
HELIPHSASIETPAMVDKKLHFGRKSRYLRHMNKKWVSSSNILYTDSDKEDHPTLRLI
SNFDSDAMIHSDLAGNFRRHSIDGRPPSQATKSSPFRSRPSSSTQHKSTTSFTQ"
gene 608946..611066
/gene="PXL1"
/locus_tag="YKR090W"
mRNA 608946..611066
/gene="PXL1"
/locus_tag="YKR090W"
/product="Pxl1p"
CDS 608946..611066
/gene="PXL1"
/locus_tag="YKR090W"
/experiment="EXISTENCE:direct assay:GO:0000131 incipient
cellular bud site [PMID:14767053]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095|PMID:23613772]"
/experiment="EXISTENCE:direct assay:GO:0005933 cellular
bud [PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005934 cellular
bud tip [PMID:14767053|PMID:15282802|PMID:22842922]"
/experiment="EXISTENCE:direct assay:GO:0005935 cellular
bud neck [PMID:14562095|PMID:14767053|PMID:15282802]"
/experiment="EXISTENCE:direct assay:GO:0030427 site of
polarized growth [PMID:23613772]"
/experiment="EXISTENCE:direct assay:GO:0043332 mating
projection tip [PMID:14767053]"
/experiment="EXISTENCE:genetic interaction:GO:0005094 Rho
GDP-dissociation inhibitor activity [PMID:15215315]"
/experiment="EXISTENCE:genetic interaction:GO:0035023
regulation of Rho protein signal transduction
[PMID:15215315]"
/experiment="EXISTENCE:mutant phenotype:GO:0030011
maintenance of cell polarity [PMID:14767053]"
/experiment="EXISTENCE:physical interaction:GO:0035023
regulation of Rho protein signal transduction
[PMID:15215315]"
/note="Protein that localizes to sites of polarized
growth; required for selection and/or maintenance of
polarized growth sites, may modulate signaling by the
GTPases Cdc42p and Rho1p; contains LIM domains and has
similarity to metazoan paxillin; relocalizes from bud neck
to cytoplasm upon DNA replication stress"
/codon_start=1
/product="Pxl1p"
/protein_id="DAA09240.2"
/db_xref="SGD:S000001798"
/translation="MYNSIYGSPFPKINPKVRYKTALERAGFDTKPRNPFSSQRNAST
GSLQASVKSPPITRQRNVSAAPSVPVTMKSAYTASSKSAYSSVKGESDIYPPPVLENS
ERRSVTPPKNSNFTSSRPSDISRSISRPSERASQEDPFRFERDLDRQAEQYAASRHTC
KSPANKEFQAADNFPFNFEQEDAGNTEREQDLSPIERSFMMLTQNDTASVVNSMNQTD
NRGVLDQKLGKEQQKEESSIEYESEGQQEDENDIESLNFEPDPKLQMNLENEPLQDDF
PEAKQEEKNTEPKIPEINVTRESNTPSLTMNALDSKIYPDDNFSGLESSKEQKSPGVS
SSSTKVEDLSLDGLNEKRLSITSSENVETPYTATNLQVEQLIAQLDDVSLSRNAKLDM
NGNCLNAVDRKASRFKKSSAYLSGYPSMDIPVTQQTSIVQNSNTNLSRQTILVDKGDV
DEDAPSESTTNGGTPIFYKFKQSNVEYSNNEGMGSQETFRTKLPTIEALQLQHKRNIT
DLREEIDNSKSNDSHVLPNGGTTRYSSDADYKETEPIEFKYPPGEGPCRACGLEVTGK
RMFSKKENELSGQWHRECFKCIECGIKFNKHVPCYILGDEPYCQKHYHEENHSICKVC
SNFIEGECLENDKVERFHVDCLNCFLCKTAITNDYYIFNGEIPLCGNHDMEALLKEGI
DNATSSNDKNNTLSKRRTRLINFN"
gene 611525..612265
/gene="SRL3"
/locus_tag="YKR091W"
/gene_synonym="WHI7"
mRNA 611525..612265
/gene="SRL3"
/locus_tag="YKR091W"
/gene_synonym="WHI7"
/product="DNA-binding protein SRL3"
CDS 611525..612265
/gene="SRL3"
/locus_tag="YKR091W"
/gene_synonym="WHI7"
/experiment="EXISTENCE:direct assay:GO:0000978 RNA
polymerase II cis-regulatory region sequence-specific DNA
binding [PMID:23382076]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:11914276]"
/experiment="EXISTENCE:mutant phenotype:GO:0006139
nucleobase-containing compound metabolic process
[PMID:9744871]"
/note="Transcriptional repressor at START; binds to SBF
(Swi4p-Swi6p) at SCB promoter elements in G1 to repress
transcription; START inhibitor that retains Cdc28-Cln3 at
the ER; acts with Ydj1p to promote release of the complex
in a growth-mediated positive feedback loop to trigger
START; unstable and degraded by SCF-Grr1 after
phosphorylation; contains a G1/S transcription factor
binding (GTB) motif; binds SBF-regulated promoters in
HU-treated cells; substrate of Cdc28p and Pho85p;
hyperphosphorylated"
/codon_start=1
/product="DNA-binding protein SRL3"
/protein_id="DAA09241.1"
/db_xref="SGD:S000001799"
/translation="MFLKTPNWETVNETPKSRVLTINELISPNLDTESNSLLATPARK
YFKTSISEAQDSPTSAPSPDGNEDPTYQYNVQFHFPGPITPTTPRSKNAEMFPSPTPP
LVSPTAVIEEENDDSVREFSRTLKSRLNCAMVKLSKEHEQVALIPPPPTEKIRKGSYS
NKFAAKHRRCHSLDESKKFLSSLEDSSAHAAFLKAISSKHAKSNRVDNVNVSPLRWSS
HRRTQSTQENSLQEVVAIDTLLKMSSSD"
rep_origin 612378..612463
/note="ARS1120; Autonomously Replicating Sequence"
/db_xref="SGD:S000118409"
gene complement(612665..613885)
/gene="SRP40"
/locus_tag="YKR092C"
mRNA complement(612665..613885)
/gene="SRP40"
/locus_tag="YKR092C"
/product="Srp40p"
CDS complement(612665..613885)
/gene="SRP40"
/locus_tag="YKR092C"
/experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
[PMID:8702624]"
/note="Nucleolar serine-rich protein; role in preribosome
assembly or transport; may function as a chaperone of
small nucleolar ribonucleoprotein particles (snoRNPs);
immunologically and structurally to rat Nopp140"
/codon_start=1
/product="Srp40p"
/protein_id="DAA09242.1"
/db_xref="SGD:S000001800"
/translation="MASKKIKVDEVPKLSVKEKEIEEKSSSSSSSSSSSSSSSSSSSS
SSSSSGESSSSSSSSSSSSSSDSSDSSDSESSSSSSSSSSSSSSSSDSESSSESDSSS
SGSSSSSSSSSDESSSESESEDETKKRARESDNEDAKETKKAKTEPESSSSSESSSSG
SSSSSESESGSESDSDSSSSSSSSSDSESDSESDSQSSSSSSSSDSSSDSDSSSSDSS
SDSDSSSSSSSSSSDSDSDSDSSSDSDSSGSSDSSSSSDSSSDESTSSDSSDSDSDSD
SGSSSELETKEATADESKAEETPASSNESTPSASSSSSANKLNIPAGTDEIKEGQRKH
FSRVDRSKINFEAWELTDNTYKGAAGTWGEKANEKLGRVRGKDFTKNKNKMKRGSYRG
GSITLESGSYKFQD"
gene 615730..617535
/gene="PTR2"
/locus_tag="YKR093W"
mRNA 615730..617535
/gene="PTR2"
/locus_tag="YKR093W"
/product="Ptr2p"
CDS 615730..617535
/gene="PTR2"
/locus_tag="YKR093W"
/experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
vacuole [PMID:26928762]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:12469340|PMID:17507646]"
/experiment="EXISTENCE:direct assay:GO:0042937 tripeptide
transmembrane transporter activity [PMID:16096264]"
/experiment="EXISTENCE:direct assay:GO:0042938 dipeptide
transport [PMID:16096264]"
/experiment="EXISTENCE:direct assay:GO:0042939 tripeptide
transport [PMID:16096264]"
/experiment="EXISTENCE:direct assay:GO:0071916 dipeptide
transmembrane transporter activity [PMID:16096264]"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/experiment="EXISTENCE:mutant phenotype:GO:0015833 peptide
transport [PMID:8264579]"
/experiment="EXISTENCE:mutant phenotype:GO:1904680 peptide
transmembrane transporter activity [PMID:8264579]"
/note="Integral membrane peptide transporter; mediates
transport of di- and tri-peptides; conserved protein that
contains 12 transmembrane domains; PTR2 expression is
regulated by N-end rule pathway via repression by Cup9p;
targeted to vacuole via AP-3 pathway"
/codon_start=1
/product="Ptr2p"
/protein_id="DAA09243.1"
/db_xref="SGD:S000001801"
/translation="MLNHPSQGSDDAQDEKQGDFPVIEEEKTQAVTLKDSYVSDDVAN
STERYNLSPSPEDEDFEGPTEEEMQTLRHVGGKIPMRCWLIAIVELSERFSYYGLSAP
FQNYMEYGPNDSPKGVLSLNSQGATGLSYFFQFWCYVTPVFGGYVADTFWGKYNTICC
GTAIYIAGIFILFITSIPSVGNRDSAIGGFIAAIILIGIATGMIKANLSVLIADQLPK
RKPSIKVLKSGERVIVDSNITLQNVFMFFYFMINVGSLSLMATTELEYHKGFWAAYLL
PFCFFWIAVVTLIFGKKQYIQRPIGDKVIAKSFKVCWILTKNKFDFNAAKPSVHPEKN
YPWNDKFVDEIKRALAACKVFIFYPIYWTQYGTMISSFITQASMMELHGIPNDFLQAF
DSIALIIFIPIFEKFVYPFIRRYTPLKPITKIFFGFMFGSFAMTWAAVLQSFVYKAGP
WYNEPLGHNTPNHVHVCWQIPAYVLISFSEIFASITGLEYAYSKAPASMKSFIMSIFL
LTNAFGSAIGCALSPVTVDPKFTWLFTGLAVACFISGCLFWLCFRKYNDTEEEMNAMD
YEEEDEFDLNPISAPKANDIEILEPMESLRSTTKY"
gene complement(617996..618750)
/gene="RPL40B"
/locus_tag="YKR094C"
/gene_synonym="CEP52B"
/gene_synonym="UB12"
/gene_synonym="UBI2"
mRNA complement(join(617996..618374,618743..618750))
/gene="RPL40B"
/locus_tag="YKR094C"
/gene_synonym="CEP52B"
/gene_synonym="UB12"
/gene_synonym="UBI2"
/product="ubiquitin-ribosomal 60S subunit protein L40B
fusion protein"
CDS complement(join(617996..618374,618743..618750))
/gene="RPL40B"
/locus_tag="YKR094C"
/gene_synonym="CEP52B"
/gene_synonym="UB12"
/gene_synonym="UBI2"
/experiment="EXISTENCE:curator inference:GO:0002181
cytoplasmic translation [PMID:22096102]"
/experiment="EXISTENCE:curator inference:GO:0003735
structural constituent of ribosome [PMID:22096102]"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:14576278|PMID:16823961]"
/experiment="EXISTENCE:direct assay:GO:0022625 cytosolic
large ribosomal subunit [PMID:22096102]"
/experiment="EXISTENCE:direct assay:GO:0042254 ribosome
biogenesis [PMID:2538753]"
/experiment="EXISTENCE:mutant phenotype:GO:0000027
ribosomal large subunit assembly [PMID:22995916]"
/experiment="EXISTENCE:mutant phenotype:GO:0000055
ribosomal large subunit export from nucleus
[PMID:22995916]"
/experiment="EXISTENCE:mutant phenotype:GO:0016567 protein
ubiquitination [PMID:8035826]"
/note="Ubiquitin-ribosomal 60S subunit protein L40B fusion
protein; cleaved to yield ubiquitin and ribosomal protein
L40B; ubiquitin may facilitate assembly of the ribosomal
protein into ribosomes; homologous to mammalian ribosomal
protein L40, no bacterial homolog; RPL40B has a paralog,
RPL40A, that arose from the whole genome duplication"
/codon_start=1
/product="ubiquitin-ribosomal 60S subunit protein L40B
fusion protein"
/protein_id="DAA09244.1"
/db_xref="SGD:S000001802"
/translation="MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLI
FAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYAR
LPPRATNCRKRKCGHTNQLRPKKKLK"
gene 619805..625432
/gene="MLP1"
/locus_tag="YKR095W"
/gene_synonym="MPL1"
mRNA 619805..625432
/gene="MLP1"
/locus_tag="YKR095W"
/gene_synonym="MPL1"
/product="Mlp1p"
CDS 619805..625432
/gene="MLP1"
/locus_tag="YKR095W"
/gene_synonym="MPL1"
/experiment="EXISTENCE:direct assay:GO:0003729 mRNA
binding [PMID:23222640]"
/experiment="EXISTENCE:direct assay:GO:0005635 nuclear
envelope [PMID:10085285]"
/experiment="EXISTENCE:direct assay:GO:0005654 nucleoplasm
[PMID:10085285]"
/experiment="EXISTENCE:direct assay:GO:0005816 spindle
pole body [PMID:16027220]"
/experiment="EXISTENCE:direct assay:GO:0044615 nuclear
pore nuclear basket [PMID:24152732]"
/experiment="EXISTENCE:genetic interaction:GO:0006606
protein import into nucleus [PMID:10085285]"
/experiment="EXISTENCE:genetic interaction:GO:0034398
telomere tethering at nuclear periphery [PMID:10638763]"
/experiment="EXISTENCE:genetic interaction:GO:0043021
ribonucleoprotein complex binding [PMID:15692572]"
/experiment="EXISTENCE:genetic interaction:GO:0071028
nuclear mRNA surveillance [PMID:14718167]"
/experiment="EXISTENCE:genetic interaction:GO:1901925
negative regulation of protein import into nucleus during
spindle assembly checkpoint [PMID:23177738]"
/experiment="EXISTENCE:mutant phenotype:GO:0016973
poly(A)+ mRNA export from nucleus [PMID:21036941]"
/experiment="EXISTENCE:mutant phenotype:GO:0071028 nuclear
mRNA surveillance [PMID:14718167]"
/experiment="EXISTENCE:mutant phenotype:GO:0090204 protein
localization to nuclear pore [PMID:19933151]"
/experiment="EXISTENCE:mutant phenotype:GO:0140586
promoter-terminator loop anchoring activity
[PMID:19933151]"
/experiment="EXISTENCE:physical interaction:GO:0043021
ribonucleoprotein complex binding [PMID:15692572]"
/note="Myosin-like protein associated with the nuclear
envelope; nuclear basket protein that connects the nuclear
pore complex with the nuclear interior; involved with
Tel1p in telomere length control; involved with Pml1p and
Pml39p in nuclear retention of unspliced mRNAs; MLP1 has a
paralog, MLP2, that arose from the whole genome
duplication"
/codon_start=1
/product="Mlp1p"
/protein_id="DAA09245.1"
/db_xref="SGD:S000001803"
/translation="MSDHDTPMESIQNGENSDERLNAIASFFGCSLEQVKSFDGDVVK
HLNDKLLQFNELKSENLKVTVSFDELKASSLKKIDGLKTEMENVIRENDKIRKERNDT
FVKFESVENEKMKLSSELEFVKRKLDDLTEEKKETQSNQQRTLKILDERLKEIELVRV
ENNRSNSECKKLRSTIMDLETKQQGYITNDLNSRTELERKTQELTLLQSNNDWLEKEL
RSKNEQYLSYRQKTDKVILDIRNELNRLRNDFQMERTNNDVLKQKNNELSKSLQEKLL
EIKGLSDSLNSEKQEFSAEMSLKQRLVDLLESQLNAVKEELNSIRELNTAKVIADDSK
KQTPENEDLLKELQLTKEKLAQCEKECLRLSSITDEADEDNENLSAKSSSDFIFLKKQ
LIKERRTKEHLQNQIETFIVELEHKVPIINSFKERTDMLENELNNAALLLEHTSNEKN
AKVKELNAKNQKLVECENDLQTLTKQRLDLCRQIQYLLITNSVSNDSKGPLRKEEIQF
IQNIMQEDDSTITESDSQKVVTERLVEFKNIIQLQEKNAELLKVVRNLADKLESKEKK
SKQSLQKIESETVNEAKEAIITLKSEKMDLESRIEELQKELEELKTSVPNEDASYSNV
TIKQLTETKRDLESQVQDLQTRISQITRESTENMSLLNKEIQDLYDSKSDISIKLGKE
KSSRILAEERFKLLSNTLDLTKAENDQLRKRFDYLQNTILKQDSKTHETLNEYVSCKS
KLSIVETELLNLKEEQKLRVHLEKNLKQELNKLSPEKDSLRIMVTQLQTLQKEREDLL
EETRKSCQKKIDELEDALSELKKETSQKDHHIKQLEEDNNSNIEWYQNKIEALKKDYE
SVITSVDSKQTDIEKLQYKVKSLEKEIEEDKIRLHTYNVMDETINDDSLRKELEKSKI
NLTDAYSQIKEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKNLTDEKTSLEDKISLL
KEQMFNLNNELDLQKKGMEKEKADFKKRISILQNNNKEVEAVKSEYESKLSKIQNDLD
QQTIYANTAQNNYEQELQKHADVSKTISELREQLHTYKGQVKTLNLSRDQLENALKEN
EKSWSSQKESLLEQLDLSNSRIEDLSSQNKLLYDQIQIYTAADKEVNNSTNGPGLNNI
LITLRRERDILDTKVTVAERDAKMLRQKISLMDVELQDARTKLDNSRVEKENHSSIIQ
QHDDIMEKLNQLNLLRESNITLRNELENNNNKKKELQSELDKLKQNVAPIESELTALK
YSMQEKEQELKLAKEEVHRWKKRSQDILEKHEQLSSSDYEKLESEIENLKEELENKER
QGAEAEEKFNRLRRQAQERLKTSKLSQDSLTEQVNSLRDAKNVLENSLSEANARIEEL
QNAKVAQGNNQLEAIRKLQEDAEKASRELQAKLEESTTSYESTINGLNEEITTLKEEI
EKQRQIQQQLQATSANEQNDLSNIVESMKKSFEEDKIKFIKEKTQEVNEKILEAQERL
NQPSNINMEEIKKKWESEHEQEVSQKIREAEEALKKRIRLPTEEKINKIIERKKEELE
KEFEEKVEERIKSMEQSGEIDVVLRKQLEAKVQEKQKELENEYNKKLQEELKDVPHSS
HISDDERDKLRAEIESRLREEFNNELQAIKKKSFDEGKQQAMMKTTLLERKLAKMESQ
LSETKQSAESPPKSVNNVQNPLLGLPRKIEENSNSPFNPLLSGEKLLKLNSKSSSGGF
NPFTSPSPNKHLQNDNDKRESLANKTDPPTHLEPSFNIPASRGLISSSSTLSTDTNDE
ELTSNNPAQKDSSNRNVQSEEDTEKKKEGEPVKRGEAIEEQTKSNKRPIDEVGELKND
EDDTTENINESKKIKTEDEEEKETDKVNDENSI"
gene 625864..626205
/gene="PCC1"
/locus_tag="YKR095W-A"
mRNA join(625864..625901,625977..626205)
/gene="PCC1"
/locus_tag="YKR095W-A"
/product="chromatin DNA-binding EKC/KEOPS complex subunit
PCC1"
CDS join(625864..625901,625977..626205)
/gene="PCC1"
/locus_tag="YKR095W-A"
/experiment="EXISTENCE:direct assay:GO:0000408 EKC/KEOPS
complex [PMID:16874308]"
/experiment="EXISTENCE:direct assay:GO:0000785 chromatin
[PMID:16874308]"
/experiment="EXISTENCE:direct assay:GO:0031490 chromatin
DNA binding [PMID:16874308]"
/experiment="EXISTENCE:genetic interaction:GO:0000722
telomere maintenance via recombination [PMID:23390378]"
/experiment="EXISTENCE:mutant phenotype:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:16874308]"
/experiment="EXISTENCE:mutant phenotype:GO:0070525 tRNA
threonylcarbamoyladenosine metabolic process
[PMID:21183954|PMID:21459853]"
/note="Component of the EKC/KEOPS protein complex;
EKC/KEOPS complex is required for t6A tRNA modification
and telomeric TG1-3 recombination; may have role in
transcription; other complex members are Kae1p, Gon7p,
Bud32p, and Cgi121p; ortholog of human LAGE3"
/codon_start=1
/product="chromatin DNA-binding EKC/KEOPS complex subunit
PCC1"
/protein_id="DAA09246.1"
/db_xref="SGD:S000028512"
/translation="MTSKREKSLDHTLELKIPFETERQATIATKVLSPDPILKPQDFQ
VDYSSEKNVMLVQFRSIDDRVLRVGVSSIIDSIKTIVEAMDVLS"
gene 626793..630380
/gene="ESL2"
/locus_tag="YKR096W"
mRNA 626793..630380
/gene="ESL2"
/locus_tag="YKR096W"
/product="Esl2p"
CDS 626793..630380
/gene="ESL2"
/locus_tag="YKR096W"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
[PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
[PMID:22375831]"
/note="hEST1A/B (SMG5/6)-like protein; contributes to
environment-sensing adaptive gene expression responses;
Esl2p and Esl1p contain a 14-3-3-like domain and a
putative PilT N-terminus ribonuclease domain; interacts
with Pex14p; may interact with ribosomes, based on
co-purification experiments; green fluorescent protein
(GFP)-fusion protein localizes to the nucleus and
cytoplasm; ESL2 has a paralog, ESL1, that arose from the
whole genome duplication"
/codon_start=1
/product="Esl2p"
/protein_id="DAA09247.1"
/db_xref="SGD:S000001804"
/translation="MPETSVQNPLRLSENENTRSMFLSASQQQRPSATPSFPRLVRNT
TANLSLSDFQVLNPSSKRQNSNSVYDDINSSKRRISRPRFSDIEGKNNDHTYPERTTV
KESEKNPSPRYVSSSKRALKRENSVGITQSSALISKSFSENGGSIAHEKWSPENMIKP
LNVSQNSLAFVDAGSDEQSKSEIVGGFQRKSNNSQEINDKDNSARDQDFNNSGNNNNN
NNHSSNNNDNNNNNNDDNNNNNNSNSRDNNNNSDDSNEREENDSCKPASNKRSGIALI
QKLQELYKVIVKQEIELQERCSQLTNSQTTELKSLWTIYKINTDLVNNYVTFITTALL
PSQPPHDLVIGQEIVEIYRIERRLWVYGTITFLDVLKNFSNFMDPEVCCQFITHVFVS
LSTMISDIPSKYSITWLQRLGDLSRMAIALYPSSFIDWKLSAEHWYTEAMKYIYNHGK
LYYHMSTVQQNTLEAFVNLGKSVFCQETFTPSPQYMQLVIDNIYQRAFVERNNGNLRN
SLLIEYLKHSEAMLLPSFLESPDLQNVVLSYFIEKFGIDANGCNIFNAEDMFVQNPDF
FKYFFRHGPSFAQSHILQIVGFGEPKNPFAILFELPKYLKERKDKKERKKSSNNDSSV
TESSTGNSRNDNEDDDEIMSSTTSISDHDLLAEFFNDIDTLRRPILPSMLTNEAWLET
LKFLNMTSLKCGIIVLRKFLHGPLGIALPHILPWIYFIISICLKSSQLSDPVSKEFWM
IIVKRAFPWDTMVTFMNVLIVYLLDNQTSNSIIGDLCDDYDKLSLSELLELFNEGEEL
PEILGCWGTLWFDTICEKNTHSISSEDNFQEIGIKDYMALDSPTDGIIFDEKDENGEK
FWKRACRTIFLFRELSRSFPIGVIIRNDPLIYRSSFQNTNILGSLVFKLEPLCNIHNN
IPVLGALESIIDISEARSENNTDLHAVPELSVNEGDNIFHYVGYKKLRADYTCFDKNG
EFLSASLYTTWYVPNSNNTNIEDNINYNSEKENEGLFLECIKSDYPEIDFKTTYFVFD
ATSWLRHSARIFKLAQNRLLRFAICLTTFQELRFLRKSKDENVMEAATRGIITIRQLY
YENKVLPLRFTGNVATHIEENLEFEEQITWRTHVDEFVIESVMKAQEKLESASEPRLS
PRRFNYVVLISDDDAMKKKAEEKEIKTLSTRFVFSLCTKLGEQRHLCTD"
gene 631152..632801
/gene="PCK1"
/locus_tag="YKR097W"
/gene_synonym="JPM2"
/gene_synonym="PPC1"
mRNA 631152..632801
/gene="PCK1"
/locus_tag="YKR097W"
/gene_synonym="JPM2"
/gene_synonym="PPC1"
/product="phosphoenolpyruvate carboxykinase PCK1"
CDS 631152..632801
/gene="PCK1"
/locus_tag="YKR097W"
/gene_synonym="JPM2"
/gene_synonym="PPC1"
/EC_number="4.1.1.49"
/experiment="EXISTENCE:direct assay:GO:0004612
phosphoenolpyruvate carboxykinase (ATP) activity
[PMID:16330239]"
/experiment="EXISTENCE:direct assay:GO:0005829 cytosol
[PMID:196563]"
/experiment="EXISTENCE:expression pattern:GO:0006094
gluconeogenesis [PMID:2689220]"
/experiment="EXISTENCE:mutant phenotype:GO:0004612
phosphoenolpyruvate carboxykinase (ATP) activity
[PMID:2689220]"
/note="Phosphoenolpyruvate carboxykinase; key enzyme in
gluconeogenesis, catalyzes early reaction in carbohydrate
biosynthesis, glucose represses transcription and
accelerates mRNA degradation, regulated by Mcm1p and
Cat8p, located in the cytosol"
/codon_start=1
/product="phosphoenolpyruvate carboxykinase PCK1"
/protein_id="DAA09248.1"
/db_xref="SGD:S000001805"
/translation="MSPSKMNATVGSTSEVEQKIRQELALSDEVTTIRRNAPAAVLYE
DGLKENKTVISSSGALIAYSGVKTGRSPKDKRIVEEPTSKDEIWWGPVNKPCSERTWS
INRERAADYLRTRDHIYIVDAFAGWDPKYRIKVRVVCARAYHALFMTNMLIRPTEEEL
AHFGEPDFTVWNAGQFPANLHTQDMSSKSTIEINFKAMEMIILGTEYAGEMKKGIFTV
MFYLMPVHHNVLTLHSSANQGIQNGDVTLFFGLSGTGKTTLSADPHRLLIGDDEHCWS
DHGVFNIEGGCYAKCINLSAEKEPEIFDAIKFGSVLENVIYDEKSHVVDYDDSSITEN
TRCAYPIDYIPSAKIPCLADSHPKNIILLTCDASGVLPPVSKLTPEQVMYHFISGYTS
KMAGTEQGVTEPEPTFSSCFGQPFLALHPIRYATMLATKMSQHKANAYLINTGWTGSS
YVSGGKRCPLKYTRAILDSIHDGSLANETYETLPIFNLQVPTKVNGVPAELLNPAKNW
SQGESKYRGAVTNLANLFVQNFKIYQDRATPDVLAAGPQFE"
gene complement(633026..635179)
/gene="UBP11"
/locus_tag="YKR098C"
mRNA complement(633026..635179)
/gene="UBP11"
/locus_tag="YKR098C"
/product="ubiquitin-specific protease UBP11"
CDS complement(633026..635179)
/gene="UBP11"
/locus_tag="YKR098C"
/EC_number="3.4.19.12"
/experiment="EXISTENCE:direct assay:GO:0004843
cysteine-type deubiquitinase activity [PMID:10527495]"
/note="Ubiquitin-specific protease; cleaves ubiquitin from
ubiquitinated proteins; UBP11 has a paralog, UBP7, that
arose from the whole genome duplication"
/codon_start=1
/product="ubiquitin-specific protease UBP11"
/protein_id="DAA09249.1"
/db_xref="SGD:S000001806"
/translation="MLLNPDQILNLVRKVYEVDIKQFYSQLRLKNLRGLLDHAAHLFN
VYLRDLEINQEMEALTAFIIGCYYLYLIIPQSLQFQTRNNLYSSYAKLKNDYQDEHVM
GYVLKVVRDESTVIVDRYLAESNGICRTIKRKRAYSLPLRPLPVHMASLSIHNKFDGS
LHEIPNELTKPTNDNSKEDIVRESNQIASSNKLEAGSEVAYYTSKEALSKPSYLKLST
GKDALFKTLSSPATAPPVHSLEVSSQIRDSSQDSSSSLSKVEKPKEEEGKIEAIESSA
PKAYNLPVIEDSNDLLSELSITGLQNPCNTCYINSIIQCLFGTTLFRDLFLTKKYRLF
LNTNKYPKEVQLSRSIYVLFKKMYLNGGRAIIPNRFLKMCKKLRPDLNIPDDQQDTQE
FLLIVLARIHEELSNENVVKYYPDLVSYDANALQVNPSKYEKWYERNVITDGLSPIDH
IYRGQLENILKCQRCGNSSYSYSTFYVLSLAIPKLSLYSFTSKSRKIKLEDCINLFTG
DEELSGDNAWDCPNCRITDSKSKKEEITSQKKKSTIFGFHSRSRSKSPHHHHHHHHSS
DDSTKNAKKRNSKKLTTIKSLDFIVLPPILVIHLSRFYYDLTKKNSTVITYPLILNII
LKNGKVIRYKLYGTVNHSGNLINGHYTSVVNKEKSHEIGLNRQVWVTFDDDYIQQHRK
DRNNFEAGKTEMSSDEVYVLFYERMDEENYEEEFC"
gene 635851..638286
/gene="BAS1"
/locus_tag="YKR099W"
mRNA 635851..638286
/gene="BAS1"
/locus_tag="YKR099W"
/product="Bas1p"
CDS 635851..638286
/gene="BAS1"
/locus_tag="YKR099W"
/experiment="EXISTENCE:direct assay:GO:0000978 RNA
polymerase II cis-regulatory region sequence-specific DNA
binding [PMID:1495962|PMID:2683089]"
/experiment="EXISTENCE:direct assay:GO:0000981 DNA-binding
transcription factor activity, RNA polymerase II-specific
[PMID:1495962]"
/experiment="EXISTENCE:direct assay:GO:0005634 nucleus
[PMID:9705508]"
/experiment="EXISTENCE:direct assay:GO:0045944 positive
regulation of transcription by RNA polymerase II
[PMID:1495962]"
/experiment="EXISTENCE:genetic interaction:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:3303332]"
/experiment="EXISTENCE:mutant phenotype:GO:0000981
DNA-binding transcription factor activity, RNA polymerase
II-specific [PMID:1495962]"
/experiment="EXISTENCE:mutant phenotype:GO:0045944
positive regulation of transcription by RNA polymerase II
[PMID:1495962|PMID:3303332]"
/note="Myb-related transcription factor; involved in
regulating basal and induced expression of genes of the
purine and histidine biosynthesis pathways; controls
cellular ATP levels; also involved in regulation of
meiotic recombination at specific genes"
/codon_start=1
/product="Bas1p"
/protein_id="DAA09250.1"
/db_xref="SGD:S000001807"
/translation="MSNISTKDIRKSKPKRGSGFDLLEVTESLGYQTHRKNGRNSWSK
DDDNMLRSLVNESAKELGYENGLEDVKTIQQSNHLSKCIAWDVLATRFKHTVRTSKDV
RKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQCAKRYIEV
LGPGSKGRLREWTLEEDLNLISKVKAYGTKWRKISSEMEFRPSLTCRNRWRKIITMVV
RGQASEVITKAIKENKNIDMTDGKLRQHPIADSDIRSDSTPNKEEQLQLSQQNNPSLI
KQDILNVKENESSKLPRLKDNDGPILNDSKPQALPPLKEISAPPPIRMTQVGQTHTSG
SIRSKVSLPIEGLSQMNKQSPGGISDSPQTSLPPAFNPASLDEHMMNSNSISDSPKHA
YSTVKTREPNSSSTQWKFTLKDGQGLSISNGTIDSTKLVKELVDQAKKYSLKISIHQH
IHNHYVTSTDHPVSSNTGLSNIGNINGNPLLMDSFPHMGRQLGNGLPGLNSNSDTFNP
EYRTSLDNMDSDFLSRTPNYNAFSLEATSHNPADNANELGSQSNRETNSPSVFYPQAN
TLIPTNSTATNNEIIQGNVSANSMSPNFNGTNGKAPSSTASYTTSGSEMPPDVGPNRI
AHFNYLPPTIRPHLGSSDATRGADLNKLLNPSPNSVRSNGSKTKKKEKRKSESSQHHS
SSSVTTNKFNHIDQSEISRTTSRSDTPLRDEDGLDFWETLRSLATTNPNPPVEKSAEN
DGAKPQVVHQGIGSHTEDSSLGSHSGGYDFFNELLDKKADTLHNEAKKTSEHDMTSGG
STDNGSVLPLNPS"
gene complement(638901..639968)
/gene="SKG1"
/locus_tag="YKR100C"
/gene_synonym="YKR099C-A"
mRNA complement(638901..639968)
/gene="SKG1"
/locus_tag="YKR100C"
/gene_synonym="YKR099C-A"
/product="Skg1p"
CDS complement(638901..639968)
/gene="SKG1"
/locus_tag="YKR100C"
/gene_synonym="YKR099C-A"
/experiment="EXISTENCE:direct assay:GO:0000131 incipient
cellular bud site [PMID:15645486]"
/experiment="EXISTENCE:direct assay:GO:0005933 cellular
bud [PMID:14562095]"
/experiment="EXISTENCE:direct assay:GO:0005934 cellular
bud tip [PMID:15645486]"
/experiment="EXISTENCE:mutant phenotype:GO:0031505
fungal-type cell wall organization [PMID:15645486]"
/note="Transmembrane protein with a role in cell wall
polymer composition; localizes on inner surface of plasma
membrane at bud and in daughter cell; SKG1 has a paralog,
AIM20, that arose from the whole genome duplication"
/codon_start=1
/product="Skg1p"
/protein_id="DAA09251.1"
/db_xref="SGD:S000001808"
/translation="MTASTSVAVGCAVGIPVGVGIIIAVCFWFNLQKRYKREEQDDRE
LERAIYDESGFVSFDNFGPLRDSKDEAALASSELKNPDHTSGSSEGSAHPEEKDGKSR
DQEKPLGKKNSKYYVPAYRRKINLLQVRNNNYGNNARQKSVVDLPSINNSSNVSLSSS
QRHITKRQISVYDQMVPVISDEGPNFFADPSSDTNTSNDQNKASMIELKHNTRQSSNE
NLIRNLQNQDFGSYYPRRASSSFLNGNISNASFHTRNSSITSVNKRDALEDVFATPKS
AAQSQLPNTFDKDNEGMDADHSVKDSRSAITDKDKDLYKLQNNYDVGNIGEIAEEDQY
ENEFTNYSQSKREFIESLRPK"
gene 640540..642504
/gene="SIR1"
/locus_tag="YKR101W"
mRNA 640540..642504
/gene="SIR1"
/locus_tag="YKR101W"
/product="Sir1p"
CDS 640540..642504
/gene="SIR1"
/locus_tag="YKR101W"
/experiment="EXISTENCE:direct assay:GO:0003682 chromatin
binding [PMID:12897051|PMID:12975325|PMID:12198162]"
/experiment="EXISTENCE:direct assay:GO:0005677 chromatin
silencing complex [PMID:8622770]"
/experiment="EXISTENCE:direct assay:GO:0030466 silent
mating-type cassette heterochromatin formation
[PMID:12897051]"
/experiment="EXISTENCE:mutant phenotype:GO:0030466 silent
mating-type cassette heterochromatin formation
[PMID:3297920]"
/experiment="EXISTENCE:mutant phenotype:GO:0031507
heterochromatin formation [PMID:2684414]"
/note="Protein involved in silencing at mating-type loci
HML and HMR; recruitment to silent chromatin requires
interactions with Orc1p and with Sir4p, through a common
Sir1p domain; binds to centromeric chromatin"
/codon_start=1
/product="Sir1p"
/protein_id="DAA09252.1"
/db_xref="SGD:S000001809"
/translation="MLQINSRLAVIDGWLVDTVKRKPINFRSPEVRLLLPNDDDYKKL
SQQNLVDWTRLKKDSNSVLVGVKSMELFKHIKLVLREFFLLEDGRIILKRIRSKLRYK
VVKKLTCKCCRLYLPKWGTVYIHPMLKDKEKPLAGVCEFSLDVNPDREYPLIEINVSH
QYIIIEGFLLYLNERRLYRWNDNNLRSQVGLTKWAHLRKTYNPVSLDILYSLNSNFYF
VKDDLLFQLLGKRVFVKFCKVMENGKCGKAPLWYRVKRTTTAKATHIAYAISNSTAPD
SFKSKNNDYRFIVREKPIVENTISNLDYSDIKKQQFTEAEVVKRKISADISQIENVHT
QFNSQKEKNNIRVNKVSSEVLDQISKFPVSRVTLLLMSAGQDKNYIELVEELARRLEK
ICIEKTTQSLEEIRDTFQANPEMQASFDKEYYQSIEEYKITLELIKEDLLITLIKQME
NMWAAEKKFSTEEEYVSPRFLVADGFLIDLAEEKPINPKDPRLLTLLKDHQRAMIDQM
NLVKWNDFKKYQDPIPLKAKTLFKFCKQIKKKFLRGADFKLHTLPTEANLKYEPERMT
VLCSCVPILLDDQTVQYLYDDSIIPEFEATSSYATKQSKCGRKMSLQMEPDLLFQEAI
RRMRHLTAYDVLRRNYIAAFEELYMGNCND"
rep_origin 642727..642973
/note="ARS1123; Autonomously Replicating Sequence"
/db_xref="SGD:S000118410"
gene 646356..649865
/gene="FLO10"
/locus_tag="YKR102W"
mRNA 646356..649865
/gene="FLO10"
/locus_tag="YKR102W"
/product="Flo10p"
CDS 646356..649865
/gene="FLO10"
/locus_tag="YKR102W"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/experiment="EXISTENCE:mutant phenotype:GO:0000128
flocculation [PMID:19420680|PMID:11027318|PMID:19087208]"
/experiment="EXISTENCE:mutant phenotype:GO:0001403
invasive growth in response to glucose limitation
[PMID:11027318|PMID:19087208]"
/experiment="EXISTENCE:mutant phenotype:GO:0044182
filamentous growth of a population of unicellular
organisms [PMID:11027318]"
/note="Member of the FLO family of cell wall flocculation
proteins; not expressed in most lab strains;
overproduction induces flocculation that can be inhibited
by mannose, sucrose, or glucose; overproduction also
promotes haploid invasive growth and diploid filamentous
growth"
/codon_start=1
/product="Flo10p"
/protein_id="DAA09253.1"
/db_xref="SGD:S000001810"
/translation="MPVAARYIFLTGLFLLSVANVALGTTEACLPAGEKKNGMTINFY
QYSLKDSSTYSNPSYMAYGYADAEKLGSVSGQTKLSIDYSIPCNGASDTCACSDDDAT
EYSASQVVPVKRGVKLCSDNTTLSSKTEKRENDDCDQGAAYWSSDLFGFYTTPTNVTV
EMTGYFLPPKTGTYTFGFATVDDSAILSVGGNVAFECCKQEQPPITSTDFTINGIKPW
NADAPTDIKGSTYMYAGYYYPIKIVYSNAVSWGTLPVSVVLPDGTEVNDDFEGYVFSF
DDNATQAHCSVPNPAEHARTCVSSATSSWSSSEVCTECTETESTSYVTPYVTSSSWSS
SEVCTECTETESTSTSTPYVTSSSSSSSEVCTECTETESTSYVTPYVSSSTAAANYTS
SFSSSSEVCTECTETESTSTSTPYVTSSSWSSSEVCTECTETESTSYVTPYVSSSTAA
ANYTSSFSSSSEVCTECTETESTSTSTPYVTSSSSSSSEVCTECTETESTSYVTPYVS
SSTAAANYTSSFSSSSEVCTECTETESTSTSTPYVTSSSWSSSEVCTECTETESTSYV
TPYVSSSTAAANYTSSFSSSSEVCTECTETESTSTSTPYATSSTGTATSFTASTSNTM
TSLVQTDTTVSFSLSSTVSEHTNAPTSSVESNASTFISSNKGSVKSYVTSSIHSITPM
YPSNQTVTSSSVVSTPITSESSESSASVTILPSTITSEFKPSTMKTKVVSISSSPTNL
ITSYDTTSKDSTVGSSTSSVSLISSISLPSSYSASSEQIFHSSIVSSNGQALTSFSST
KVSSSESSESHRTSPTTSSESGIKSSGVEIESTSTSSFSFHETSTASTSVQISSQFVT
PSSPISTVAPRSTGLNSQTESTNSSKETMSSENSASVMPSSSATSPKTGKVTSDETSS
GFSRDRTTVYRMTSETPSTNEQTTLITVSSCESNSCSNTVSSAVVSTATTTINGITTE
YTTWCPLSATELTTVSKLESEEKTTLITVTSCESGVCSETASPAIVSTATATVNDVVT
VYSTWSPQATNKLAVSSDIENSASKASFVSEAAETKSISRNNNFVPTSGTTSIETHTT
TTSNASENSDNVSASEAVSSKSVTNPVLISVSQQPRGTPASSMIGSSTASLEMSSYLG
IANHLLTNSGISIFIASLLLAIV"
gene 653080..656736
/gene="NFT1"
/locus_tag="YKR103W"
mRNA 653080..656736
/gene="NFT1"
/locus_tag="YKR103W"
/product="putative multidrug transporter NFT1"
CDS 653080..656736
/gene="NFT1"
/locus_tag="YKR103W"
/experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
vacuole membrane [PMID:23658021]"
/experiment="EXISTENCE:mutant phenotype:GO:0016236
macroautophagy [PMID:19793921]"
/note="Putative transporter of the MRP subfamily; adjacent
ORFs YKR103W and YKR104W are merged in different strain
backgrounds; MRP stands for multidrug
resistance-associated protein"
/codon_start=1
/product="putative multidrug transporter NFT1"
/protein_id="DAA09254.1"
/db_xref="SGD:S000001811"
/translation="MIKNGTCPYWERDDLSECARREYIEFKFPLFILLTGMIYAFCKV
FRAFYLRGKNHTNEAPEFEEQGNGNHEYARFSVLRLKSAWESRSFCNVNNRSTFDKFK
KFIEGAFIVLQLTIHLYILSSMPMDNKKFFHQGFLVQMFLWILLLVVITLRLISASQS
FRWVLACKRDLWAVSFYSYASLFTLSILPLRSVFIGKIKDKIMVKYIISETFIDLALL
LLLSTSSIEGTRYSFLVENENKKLPPAPTVFGLLTFSRIDRLIWKAYKHCLGNADIWD
LDINNKSIAILANFEMSSKKGRLLPNIICYFKAVFISQLFLAFVSSFLNFVPSLLMPR
ILSYVNDPKSKSWNLVSLYVSSMLVSKIIATTCRGQGLFLGEKGTMQLRTVLISNIYS
KTLRRTILKDSTTSLQKNASTSFEENPDSSEAEPRKKSSRKDNSVNNVMSIDAFKVSE
AMNTFYLACEAVFMTVTALMILYSLLGWSAFAGTFALLAMIPLNFWCATFYGNYQADQ
LILTDKRTSGISEALNSIRVIKLLAWENLFYQKIINVRDGEIRLLKKKATIFFLNHLI
WFFGPTLVSAITFSVFIKFQNQTLTPTIAFTALSLFAILRTPMDQIASTVSLLIQSFI
SLERIQDYLNESETRKYEILEQSNTKFGFEDASMEWEAAETSFKLKNISIDFKLNSLN
AIIGPTGSGKSSLLLGLLGELNLLSGKIYVPTVESRDDLEIGKDGMTNSMAYCSQTPW
LISGTIKDNVVFGEIFNKQKFDDVMKSCCLDKDIKAMTAGIRTDVGDGGFSLSGGQQQ
RIALARAIYSSSRYLILDDCLSAVDPETALYIYEECLCGPMMKGRTCIITSHNISLVT
KRADWLVILDRGEVKSQGKPSDLIKSNEFLRESINNDSKNTTHNQIDLKRSTTSKKTK
NGDPEGGNSQDEVCAEVENFEETKMEGSVKFSAYKWLADYFGGLGVVFVFTSSSILIH
GITLSQGFWLRYWLDTGSSGSKSTWLYRIVEGHSNIYFLLTYIIIGLVSSFLTSGKVW
IAIISGTNVTKKIFAKLLSSILYAKLRFHNVTPTGRIMNRFSKDMDIIDQQLIPNFEG
LSYSVVVCLWIILLIGYVTPQFLLFAIPLCALYYTVCTLYLRASRELKRIDNINISPI
HQLFAEAIKGVTTIRALADERRFITQSLVAIDRSNAPFFYLNMATEWITYRVDIIGTL
VLFSSSVMIIMKAS"
gene 656836..657756
/locus_tag="YKR104W"
/gene_synonym="NFT1"
mRNA 656836..657756
/locus_tag="YKR104W"
/gene_synonym="NFT1"
/product="hypothetical protein"
CDS 656836..657756
/locus_tag="YKR104W"
/gene_synonym="NFT1"
/note="Putative transporter of the MRP subfamily; contains
a stop codon in S288C; adjacent ORFs YKR103W and YKR104W
are merged in different strain backgrounds; MRP stands for
multidrug resistance-associated protein"
/codon_start=1
/product="hypothetical protein"
/protein_id="DAA09255.1"
/db_xref="SGD:S000001812"
/translation="MSSVERIKEYTDIPSESNGYISPPANWPQTGDVELKNLSLRYSP
HSSKALDNVSFKVKAGTKVGIVGRTGAGKSSIIAAIYRLSDWENGTITIDNKDIKHIP
LERLRNSISCIPQDPTLFDGTVRSNLDPFDRYSDVQIYGVLSKVGLIEECDELCLIFE
QEQPNFSSHKLRNRFIDLNTVVKSGGSNLSQGQRQLLCLARSMLGARNIMLIDEATAS
IDYISDAKIQKTIRETMKNTTILTIAHRLRSVIDYDKILVMEMGRVKEYDHPYTLISD
RNTIFYRLCRQSGEFENLFELAKVSFDNKR"
gene complement(658716..660464)
/gene="VBA5"
/locus_tag="YKR105C"
mRNA complement(658716..660464)
/gene="VBA5"
/locus_tag="YKR105C"
/product="basic amino acid transporter"
CDS complement(658716..660464)
/gene="VBA5"
/locus_tag="YKR105C"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:23047103]"
/experiment="EXISTENCE:genetic interaction:GO:1903826
L-arginine transmembrane transport [PMID:23047103]"
/experiment="EXISTENCE:mutant phenotype:GO:1903826
L-arginine transmembrane transport [PMID:23047103]"
/note="Plasma membrane protein of the Major Facilitator
Superfamily (MFS); involved in amino acid uptake and drug
sensitivity; VBA5 has a paralog, VBA3, that arose from a
segmental duplication"
/codon_start=1
/product="basic amino acid transporter"
/protein_id="DAA09256.1"
/db_xref="SGD:S000001813"
/translation="MEETKYSSQQEIEGACGSDASLNARGSNDSPMGLSLYLCLASLT
LVLFITALDILIVGTIIDVVAEQFGNYSKTGWLVTGYSLPNAILSLIWGRFASIIGFQ
HSLILAILIFEAGSLIAALASSMNMLIFGRVVAGVGGSGLQTLCFVIGCTMVGERSRP
LVISILSCAFAVAAIVGPIIGGAFTTHVTWRWCFYINLPIGGLAIIMFLLTYKAENKG
ILQQIKDAIGTISSFTFSKFRHQVNFKRLMNGIIFKFDFFGFALCSAGLVLFLLGLTF
GGNKYSWNSGQVITYLVLGVLLFIFSLVYDFFLFDKFNPEPDNISYRPLLLRRLVAKP
AIIIVNMVTFLLCTGYNGQMIYSVQFFQLIFASSAWKAGLHLIPIVITNVIAAIASGV
ITKKLGLVKPLLIFGGVLGVIGAGLMTLMTNTSTKSTQIGVLLLPGFSLGFALQASLM
SAQLQITKDRPEAAMDFIEVTAFNTFMKSLGTTLGGVLSTTVFSASFHNKVSRAHLEP
YEGKTVDDMILYRLQNYDGSHSTIGNILSDSIKNVFWMDLGFYALGFLFCSFSSNKKL
IIPKKDDTPEDNLEDK"
gene 661442..663289
/gene="GEX2"
/locus_tag="YKR106W"
mRNA 661442..663289
/gene="GEX2"
/locus_tag="YKR106W"
/product="glutathione exchanger"
CDS 661442..663289
/gene="GEX2"
/locus_tag="YKR106W"
/experiment="EXISTENCE:direct assay:GO:0005774 vacuolar
membrane [PMID:21490148]"
/experiment="EXISTENCE:direct assay:GO:0005886 plasma
membrane [PMID:21490148]"
/experiment="EXISTENCE:direct assay:GO:0071944 cell
periphery [PMID:26928762]"
/note="Proton:glutathione antiporter; localized to the
vacuolar and plasma membranes; expressed at a very low
level; potential role in resistance to oxidative stress
and modulation of the PKA pathway; GEX2 has a paralog,
GEX1, that arose from a segmental duplication"
/codon_start=1
/product="glutathione exchanger"
/protein_id="DAA09257.1"
/db_xref="SGD:S000001814"
/translation="MSSSVVGASSNKKSGIRQSCEIIERERHSNDDTYSMTSTFFKLK
ENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQV
INAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNC
GYVGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIA
MWAFIYPLSTLPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDI
VGILLITVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPL
LPFKLLSDRGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVA
ATASPFYSLLVAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLS
GLLCSNSVIVILQAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKN
LGNDTLAEIAYASPYTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFTFTM
FMRNPELIDKATHEEFTEDGLVVLPDEENIFSQIKALFRHNRSNKKSGC"
repeat_region 665430..665668
/note="Ty5 LTR"
/rpt_type=long_terminal_repeat
/db_xref="SGD:S000007063"
telomere 665904..666816
/note="TEL11R; Telomeric region on the right arm of
Chromosome XI; composed of an X element core sequence, X
element combinatorial repeats, and a terminal stretch of
telomeric repeats"
/db_xref="SGD:S000028978"
BASE COUNT 206161 a 127768 c 126085 g 206802 t
ORIGIN
1 caccacaccc acacaccaca cccacacaca caccacaccc acacaccaca cccacacacc
61 acacccacta ctctaaccct attctaatcc aaccctgatc aacctgtctc caaacctacc
121 ctcacattac cctacctctc cactcgttac cctgccccac tcaaccatac cactcccacc
181 caccatccat ctctctactg tcaccagccc accgtccacc ataaccgtta ccctcccatt
241 actcatattt aaccccacta ccacttaccc tgccattacc ctaccatcca ccatgtccta
301 ctcactgtac tgttgttcta ccctccatat tgaaacgtta acaaataatc gtaaataata
361 cacatatact taccctacca ctctaatccc accacacatc acatgccata ctcaccttca
421 cttgtatact gatatggtat acgcacacgg atgctacgta tataccactc tcaacttacc
481 ctactctcac attccactcc atggcccagt ctcactaaat cagtacgatg cactcacatc
541 attattcacg gcacttgcct cagcggttta taccctgtgc aatttaccca taaaacccac
601 gattatccac attttaatat ctatatctca ttcagcggct ccaaatattg tataactgct
661 cttaatgcat acattatacc acttttactc catatactaa ccattcaatt tatacacact
721 tatttcaata tacccacaaa atcaccacta aaattaccta aacataaaaa tattctactc
781 ttcaacaata atacataaac acactcaatt gcgtatctat accaccatga cgtcattaac
841 gtaaaagttc cttaatatta ccattgcttg aacggatgcc atttcaaaat atttcgtact
901 tacacagacc atacattaga ataatatgca cctcactatt gtaacactct ttattcacta
961 agttataata tagtagtggc tcacactcat gcgggtgcta tgatacaatg gcatcctatt
1021 tccattccca tatgctaacc gcaatatcct aaaaggataa ctgatgtatc tttaatcttg
1081 tatgtgacac tactcatacg aagagactat atctgaacaa gacgatactg tgataggtac
1141 gttatttaat aggatctata acgaaatgtc aaataatttt acggtaatat aacttatcag
1201 cggcgtatac tgaaacggac gttacgatat tgtctcactt catcttacca ccctctatct
1261 tattgttgat agaacactaa cccttcagct ttatttctgg ttacggttac acaaaaacta
1321 tcgcaaccca gaaattttga tattttcagt gtcaaaaaat gagggtctct aaatgagagt
1381 ttgataccat gactccgtaa ctcgcactgc cctgatctgc aatcttgttc ttagaagtga
1441 cgcatattct atacggcccg acgcgacgcg ccaaaaaatg aaaaaagaag cagcgactca
1501 tttttatgga aggacaaagt gctgcgaagt catacgcttc caatttcatt gttgtttatt
1561 ggacatactc tgttagcttt attaccgtcc acgctttttc tacaatagtg taaaatttct
1621 ttctatgttt atcatattca taaaatgctt cacgaacacc gtcattgatc aaataggttt
1681 ataatattaa tatacattta tataatctac ggtatttata tcatcaaaaa aaaagtagtt
1741 tttttatttt attttgttcg ttaattttca atgtctatgg aaacccgttc gtaaaattgg
1801 cgtttgtctc taatttgcga tagtgtagat accgtccttg gatagagcac tggagatagc
1861 tggtctcaat ctggtagagt accatgggac accagtgata actctggtga cttgttcagc
1921 tggaatacca gtcaacatgg tggtgaagtc accatagttg aaaacagctt cagcaatttc
1981 aactgggtag gtctcacttg gatgagctgc ttgaaacaag tagtattggg ccaaatgagc
2041 tctgatatcg gagacgtaaa cacccaattc gaccaagtta actctttcgt cagatggaga
2101 tagagtggta gtggctgggg cagcggcaac accagcagcg atggcggcga caccagcagc
2161 gattgaagtt aatttgacca ttatatttgt tttgtttctt agtgctgata taagcttaac
2221 aggaaagaaa ggaataaaaa catattctca aagacataca gttgaagcag ctctatttat
2281 acccatgcct tcatcagtca tcactactta aacgattcgt taacaagtgc tcatttagca
2341 cctcacatat cctctatatc tcatctttca cacaatctca ttatcactat ggagatgctc
2401 ttgtttctga acgaatcata catctttcat agacttcgta tgtggagtac tgttttatgg
2461 cactcatgtg tattcgtatg cgtagaatgt gagaatgcca attatagggt gccgaggtgc
2521 cttataaaac ccttttctgt gcctgtgaca tttccttttt cggtcaaaaa gaatatccga
2581 attttagatt tggaccctcg tacagaagct tattgtctaa gcccatattc agtctgctct
2641 aaacggcttc catgcaagaa atatttctat ctcttgaatt cgtacaacat taaacgtgtg
2701 ttgggagtcg tatactgtta gcgtctgcaa attcgtgaat tctccgcgaa tgccttggtg
2761 caattacgta attgtagccg ctgaaggcgg atggtattga gagaagttga tgttcaaaga
2821 atcgtgtatg ataaaaataa aattgtaaca gtttataaat actaaacttt acttgaaaag
2881 tcttttagtc cgaaaatgaa tgtgggaata ctaattacaa gcctcccatg gcacttcttc
2941 atttcttttt gactacgaac atggcacttt ttcaattaat tatatttaat aaatatttct
3001 ttttacttaa attttacaaa acccaaggtc attatggtga ttaaaccaca gtatatatat
3061 gtatatgttg aagaggtttc aattcggcca aaacgacagt actatatctg agtctgcact
3121 agacaatatt gaatttactt accaattagc attaatatac cagaaaaata tcgaatttct
3181 ttttccggaa taaaatactt ctctttcaaa atattcattt gcaaattaga atacatagga
3241 tattatgatg tgcacctaaa atatagagaa acatacttag aacttacata tcaaacgtta
3301 tcttagttat taaaaatgaa aaatagctgg gcagtgacac ctgaaatacc ccaaaaaaaa
3361 gagcaactat ctagaaaagt atgtagaagt ccgaaaggaa cagagggtgc caccaatagc
3421 tttcacaaag agttcctttc gtgttggcaa aaaaaatgag tcacttacta caggttcaat
3481 ttttataatt caattgttgt acctatctgg aaaagaagtc ctcaaaatta ctccacccgg
3541 aaatagctgt atcaaagaag gcacttggag aacctaatat atcatcgatg aaattttccg
3601 agaaatcttc taaaggtccc tctaaatcat ttagtatagt tgttaaactg ttttcagttg
3661 catcattttc ggtttcaggc ccttcatcga tatttttcat tcctttgtta aaagctcttc
3721 ttcctatttt ttccattgat ataataatag aaaagtaata ggagttttgc caaatttgag
3781 taagaggttt caacttttct tggtgaatat gatcaaatat gttttccatt tctttaaatg
3841 caattttcag tgaaatacac ttattgtgtg gaccctcaaa gtctccagga catatagaat
3901 aagttagtgc ggacgaattt ctctgaatga ataattggat atctttattt tccatatact
3961 gtagaaaaat ggtataaatt tgaattaatg ctctgaaagc gttcacataa ataagaaaca
4021 acgcattgtt taaatggggc cattttttgg agaggcataa tgacttagaa gataatttgc
4081 tgttgtctaa ttcaaaatag gtctcaagga cattaaagca caaatgtaat gaatttagtg
4141 gagccaggac gctaaaattg aatattctcg catcaaaatc ttgatgtgtt aaggtataaa
4201 gattggataa acttcctatc atatggagag ttgcatgcca taattgaagt tcggtgaact
4261 cattaccatt taaattagat gcatttaagt aaaaatccaa cggcttaaac attttaatgg
4321 tgaacttttt taagtcctcg atgatgagtg gaatgtcagg cggtttctca cgagcatgaa
4381 tttgtttcat aatatttctc agtcttaatg ttgttttata cagaaggatg tcccctgatg
4441 aagaatagtt ttctagacgt accttgttta caaaatcgtc gttgattcgg accggaattc
4501 ctgtagagag tgaaatttta acgtccgtga ataggatcca taaccacaat ctctccaagt
4561 aaggtatttc ctctattgga tgatttttac tcagatataa acgacgaaga tcttcattaa
4621 ggcccatatg gatagctgtg tcaattgtca gaccatgaat aaatatgcaa tgtgactgat
4681 cgcccccgtc aagacccgcc acatttatgt acaggtaacg taaaaataaa aattgcacac
4741 gctcagtata aaaaacttta gccgaaacaa aagacgttaa aactttatgg aagacttcaa
4801 tagcctctgg cacttctttt ggatgggatg ctaagcacat aatggctgtc ataacaccca
4861 ctttataata atttttttta ctgtccagat taagggaaat tattgtgtgc tgaccagttt
4921 tatgacttct tgggccttta acaaaacaat cttgcagatc ccttaatact ttttctttat
4981 gaacaatttg gtaactatcg taaaaatcgc tagcaaaaaa atcagttaaa tactcacaca
5041 aaacttcata atttggaagc gattcacata agtattcaat aacacttggt gagcctgagt
5101 gcggtggggc agtctcaatg gaactaatct ccgagagtgt tgagtaatga tgctctcttt
5161 tccagttgtt acggctgagt tttaggactt gccatatctc ctctctgtat ttggcaaaag
5221 tatctgtttg agttgctaat attgctcgat acgacgttgg tccataaaga atgtgcctat
5281 tgtgctttga agataaatat ctcatgttgg aaagagggtt ttgtccttcg tgaatgttag
5341 gctgggattg ttttgttagc tgagattcaa gctcttcaat acgacgagcc atctctaatt
5401 ttgaacatct cctgtatttt ttcctgagtt ggtcctccat ggcggaagtg ttttctttat
5461 attcacattg ctttcgattt cgagaagagc aacttccaca gaacggtctt actcgatcgc
5521 acttgagctt tcttactcta caaaagtggc acgactttgc aggctttctt ctactctgcc
5581 tatctaattt ttttttttga ctaagttccg tattcttcat tttctattga ttatggaaag
5641 tatattgcta cagattcatt atttccaaag caaccgttat tggttactag tgctggacaa
5701 ttgatatgta atcagttgct atacatctag atcaagttgc tctcttcttt tgacgtttcg
5761 aatatttttt gacttcaaac ttgaagtgca cactcatctt ttcaaggttt tttatgattc
5821 tccgttttat ggctattccc gcttttaaca tagaggcgat gcatggaaga caataattat
5881 tttaaggtgc ttttgagatc aagatatttt taagagtact cactatgggt atgagataat
5941 aaaatatatt ccgttttctt attatttcca ttcttcagat ttttacaggc taaacacaca
6001 tatataaaaa tgccatcgga tattcaattc agtatcctgc tattgatata gaactatata
6061 actgatacta gaatatacta attcgtgcac tattaaccgt ttggcgatgt ccgaagaacg
6121 gcatgaagat catcataggg atgttgaaaa taaattgaat ttaaatggta aagacgatat
6181 taacgggaat acctcaatct cgatcgaggt gcctgatgga ggatatgggt ggtttattct
6241 tcttgctttt attctgtaca acttttctac ttggggggca aattctggtt atgctattta
6301 tttagcgcat tatttagaga ataatacttt tgctggtggg agtaaattag actatgcttc
6361 tataggtggg ttagcattca gttgtggact tttttttgcc ccagttataa catggcttta
6421 tcatatattt tcaattcaat tcattatagg cttagggata ctgtttcaag gggcagcgct
6481 actgcttgca gctttttctg tcacactctg ggaaatttat ctcacgcaag gcgttttaat
6541 tggattcggt ttagcattta ttttcatacc cagtgtcaca ctcatcccac tatggttcag
6601 aaataaaaga tctttagcct ctggtatagg aactgctgga agcgggttag gtggtattgt
6661 ctttaacttg ggaatgcaaa gtattctaca aaagaggggc gttaaatggg cgctcattgc
6721 tcagtgcata atatgcacat cacttagcac cattgcgctt atgttgacca gaacaacaca
6781 tcaaggccta cgtcaacata agagatctta caaatttgaa ttgctagatt atgatgtgct
6841 ttcaaatttc gcggtctggt tactttttgg atttgtatca tttgctatgt taggatatgt
6901 tgtccttttg tattccttgt ctgattttac cgttagttta ggttatacta gtaagcaagg
6961 ctcatacgta tcgtgcatgg tgagtgtcgg ctctctgctg ggacgaccaa ttgtgggtca
7021 cattgctgat aaatatggat cactaacagt tggcatgata ttgcaccttg tcatggccat
7081 cctttgttgg gccatgtgga taccttgtaa aaatttggcc actgcgatag cttttggatt
7141 attggttggt tctattatgg gaacaatttg gccaacaatt gcttcaattg ttacacgcat
7201 tgttggtctt caaaagcttc ctggtacctt tggtagtacc tggattttta tggcggcttt
7261 tgccttagtt gcccccataa tcggtctgga acttcgttca actgatacga atggaaacga
7321 ttattatcgt acagcaatat tcgtgggttt tgcgtacttt ggtgttagtt tatgccaatg
7381 gctattgaga gggtttataa tagctcgaga tgagattgct gtgcgtgaag cctattcagc
7441 tgaccaaaat gaattgcatt taaacgttaa gttatcacat atgagtaaat gtctttttcg
7501 ttataaacaa ttacctagga gagtctaaag gtcactttta tttcacactg tagataagaa
7561 ggggatagag ttgccagaaa attttttgct ttatcagctt tttagatttg tcttctcgtt
7621 ttataaataa tgataattta gtacaataat agataataaa aacatttttt tttgcaaatt
7681 gaaagcttaa ctggtttttt aaaagaaaat attagtgacc ttctaccgac taaaatcttc
7741 cactaaatcc ccagtagaaa cataagataa ggttgaaact tttttagggc gattatattt
7801 ttagtcctat acatgtttga tggcatactt tttaaggaag atttatgaag ctatgttcca
7861 cataggttta tgtgctattg atatatacta taaataaaac gctctaccca agaaatgaaa
7921 cattttttaa acttttgtca tcagcacaaa aatatgcgga tttacgcgtt tgtcattcct
7981 ataaacctta accttaacgc gaaaccatat ttcgctacct aatgttggtt cggtgcattt
8041 tgagaaaagg aactaggttc agatatcatg catcgaatct attatcttcc aaccgaactt
8101 ttacaaacgt ttagaccgag cgttattgac tgaattaaga gcaagttttt acacgtgtga
8161 ctctggcaca ttagagctgt ttgagaatct aaagtcttgc tgtctaagga ccaaaaataa
8221 tgtatttcga ggtcatagct aagaatctca ttgttcttca gcacttgcta atcacatatc
8281 tatttctaag tacaagatga tagttaacaa ctaataatga ataaaccagg taaaaaaaaa
8341 aaaagaaaaa gctgtaaaag acgacaacgt tggcgtcgcg aaaatattaa tagaaccata
8401 tgttggataa tgtagcctct attatacact tatcccgatt acattgtttt agcgacggta
8461 atcatctttt tatccggcac tctgaatcaa actctatctt taagtatcct atatgcatga
8521 gttatgtcga ttatatcgaa gactcggtgt gtgatattac tccacagtac aaaaacagga
8581 atacagagaa aattgaaaag atatatgaac ggatggtatg gtaaataaaa taacagccat
8641 tataaagctt gtggtaaatt ttccaggacg gaagttagct tatgcagttt tgtttatctt
8701 ccttgcatct gtgtataata ctgaaacacg caattaacgt ttcataaaat ttgcctgagg
8761 gccgtataaa aattcagtga ccattgttca cactttaaat atagccaaat tgccaagaaa
8821 gggtttcatt gcaggtttat cgaaatatta actctttaaa tacagggact atacagagct
8881 aacttcttaa gaaaaaaaac catgcgacac actacgactt tcacaaattc cataaaagag
8941 atatttaaga tttagataaa atatcaaagg actgctgtac tctgcttcaa ttacctcctt
9001 accataaagt tataggcagc tttctccatc gacatactaa aatttggata ggtattatta
9061 atgaaatgac tagttttaag taaaaaatga tcaccagcat tgatactctt caaagtactc
9121 aatggctttt gcagacttat ctaaaactat ttttgcggtt tcattcctca ctttgtcaac
9181 aaaaatagga ggtccacagc aaaccacaga taatgagcca ctcaattcag ccgcttcatg
9241 tagaagttcc ttaacatttg gtcgcccgca atggaaaaca acaccatcaa aaccaagtgg
9301 attggcagac ttttctaaag tagttgccac aacagtgcct ttttcatcag ccttctcatc
9361 ctgttgagaa atatctaaac tatcactagg ggttaatgat gggacttcca ttgtgttgta
9421 gatgtgaagc tgtacattca gattttctaa acacatcaac tccggcttat aagcctcgag
9481 tacgtcgaat cctctaactg caatcactaa ttttacagat tgttttccag cagccgctga
9541 cgtctttcca agtttaattg catgtgcaat aggtccaggc aaaccggtac ctccagtgag
9601 taacaataca ttattgtaat tattgaccgg agatgaagaa ccatatggac cttctatagc
9661 tagtctcata gatgtcttac ctccattgcg acacacatac tttttgacaa gtcttgttac
9721 tccctttttt tctttcagga taataaccag ttcaccattc ttgcttactg aatccaaaac
9781 agtaaatgga tgtgactgcc agaagtacag tggatgtaaa aacgaaacga aaacatattg
9841 cccaggtttg gccctccatg gccttgccgg ttttttaact gttaaacgaa tgagatcatc
9901 cccgattagt tgtagggaag ctttggggaa accaaaataa gaagctttga taattctaat
9961 aatccggtca acgatccaaa tcgcaatagc agtgtatatc cactcaatgc cacttaaact
10021 aacaacatgc tcccaacatg cataaaagaa cattgcacca aggacgatat gaagaaaaag
10081 aaaggcttca taaaaatact tcctgaatac tgcaaaggaa aagaaaacca ttgtgccagc
10141 taaacaaagt gctgccaccc cgaattgcca atataatcgg tttttacttg ttgcccaagt
10201 tttattcgct accgtataac tagtatatgc agagccatga atcatagcat ccaaaaacat
10261 cattcttccc aaccatttgt gaaacataat gaaggaagta tatttaaccc cagaaatata
10321 ctcgagaaag ttgtttcttc ccgcgaaaag aactattaat ggaaagtgtg cgaatgcgag
10381 tacaccactt ctgtctgcca catatcgagc aacttgaact ctacgagact tgaatattat
10441 attttcagga tcgtattcat aaccgtatgc caaaaaaacg gtatgaagca cgagatatcc
10501 aagaataatg ataccctcta atcttgtagg taaatatcct gtgaatattc taaaataaga
10561 gaaatctgac gcatgtttgc ttccaatggt aggtagagtg aggtatcccc ttacatatcc
10621 cacaagcttt tgcttcaata gaacagtttt aaagggagtg taattcatgc aatgaagaac
10681 gcctgcaaaa gccatgatag cgacaaaata agcacatata atgccaccat atatgtttcc
10741 gacatctaag ttagcataga aaccatgcaa tgcatgatag taggcttttc ttaactgtgt
10801 atccatttca actggatatg ttaggtttgc actgcctttg acatagggcg tcatatgcct
10861 cgttccgttg tttagaacgt cataaaactc agaattagtc atgttctgaa gagcatcact
10921 ataacttgca cagttttttt tgatggtact aaatgttttt tctaaggttt tattcgaata
10981 acctttttca tccaacgttt catagataca atacagcatt gattgaaacg ctggttcgta
11041 agaacatact ggtgatgaac gcttagactt gctggtatac tcccaagtaa ctttttgaaa
11101 aatcctcgtg caggcattag tgacaagcaa gggcaccttg ttacgaataa ctgtctttgc
11161 aggtgatgct cttgctcctg acaggcagaa aagcaaaata gcgctcaaga tggacgtcca
11221 atgcattata ttcgttgggt ttcataagct ttggataaaa aagactttat tacaactgta
11281 gcaaaaaatc atgttcattt tttgcgactt atatatttag tggcaaatta atgatacctt
11341 gcaataaccg aatttagagt atgttgtcca agaaaggagg gattttgttc atcagaaaag
11401 aattcagaaa agcaaggaaa cagtactatc gtttagaatg tagaatgata ggttgcttgc
11461 taattctatt atggcacgaa tgatacaccc atattttcaa caaaatcaat acccactagc
11521 atcattgagc caactatttg tcaatgcaac cattaccggt acttcatcct gatttaacga
11581 gtctactttt ttatcacgtc aaaatttact tgttttcctg taaacccgaa ataaaggcaa
11641 aaaagacctg ggtgcaatta cgaataaatg tacaataatc atcctgtttg catagtaaac
11701 ttccagttag agtcacacaa cgcaatgaat tttgacagtt ttctgtgcga tattctttgg
11761 taaacgtaaa gaacaggcaa cttttggtac aatggattct agcccatatg gttcatttct
11821 ggtgcattcg caaagtcagt atttgtctag ctgtgttttc tggctgagag acattatgat
11881 gttattcatt gttatggata tctctgtagc tcatgctgct tatttctccc taaaaaagtt
11941 ttttctctcg aatacattct tgaccatttc atagtgaaat tcttgtactt atttaaaacc
12001 aaaaatggaa gtattcatac atccccctat caaaaacact caataagttt cgaattattc
12061 gttcgtctaa acagtgtcca atactcaaag gggtattcaa gacggcacaa aatcagcatc
12121 ttcccttatc cgtgttccag aaataccacg ctaaggtttt tcctcctaca atccataaaa
12181 tcattaagga ggcagcttga aaaatcttga aattcaaaag agttatcttg ggctaatcga
12241 aattaacgat aaccagagta gaatattcaa gatcacagct ccaccttagt ttcgaggttg
12301 ctctcaatgg tctagcttag tcatgctttt tgttaaacaa atcttgcctt ttctgatatt
12361 ctatagtgtg gtccaatcca gatattggcg catcctaaac caattatagt tcacttatga
12421 agggcaaatg aacactctta ccagtttcac aaataattag tactagctag gcggtcaaac
12481 tgactagctt attataatat tatcgatgta acatttttcc atagtgaggg aggaaaataa
12541 accttaaaaa aatatgcaag gattctagat ttcaggctag tcttcaacca ctttgcactt
12601 ccggattaaa ggcttttata gaaaacatct tggtttggga ctatattgct aggtgaaaat
12661 ttcaaaattg tacaaaagat cattcttgtt tttttgcctc attagctgat acaatgcgga
12721 actacatggc gctcttttat aagcatctac tatggtacat tctaagtatg tggatcttgg
12781 ttaacacata gacatttttt aacttcttga tatcggttcc gctaaatttg ctgattatat
12841 ttgttcacta ggccagatca taatgcctgt aatattgagt acttaatatc gatacttgat
12901 atccgaacag taaacgtttg tccgtagtca tcgtgactgt tgacgtatta actgcaagaa
12961 atgatggaaa aaatttaggt atatttgcag atgaaaactc tagaacactg ccgttgaaga
13021 aagaatggct tcagccgtca tgctgtctat ctgtttgtaa acttttggaa gttttacata
13081 ttttgcacta ttttctttag cacgaggtat atgtttcttt ttcaataaaa atcgtccttt
13141 tgaagagcca agaacacttt tgatttgagt gtataggata ataatattgc ttctagcgct
13201 taatgaccat gtttgtactt acctctctcc caccttgtat aggcggattg gctataataa
13261 cgcgttatat gcatcaaaat atgtagttct ctttcatttt agcaaattcg taatacgact
13321 ccagataata ataccaagtc atttttgggt accagtgaga attgggtctc ataactgatt
13381 gtgaatctca atattacagt gatgtgaggg aaaatactta attaaaaagg aaaaaagaaa
13441 tgttactttt ctattttaaa tgaagattca gtttgttaaa catggatttt ccatagcatt
13501 aggtttttat atttccaaat ccattttatt taaacttttg aatcatggga tataaagtta
13561 catgcaatag gaaaagttgt catgaactcc atttgaaact aaggaagaac agtaacagaa
13621 gttttttgtt atgaattatt catgaactta gagctgctaa tttggagtgg gtccaagtca
13681 tcattttttt gcggggctat gattacacaa tctgcgcaca taatataatc ggctttgtat
13741 ctttaacatc aagtaagacc ttgaaaattt attctatctt tagacaatga acggagttac
13801 agaacgattt tcgtcttccc catttgatca aaaactaact gaaaattgca gtgttgtaat
13861 ttttgaaacg ccgaacgaag ttttcaccaa cttaacagaa gcagaagacc gttcttgaac
13921 taggctgcac tgtagaacgc tgagcacttt accattcacc acgctatttt caacggaaaa
13981 atcaataaat ccttgaattg ccttcattta aatgccaatt acacctcgta tatctaaaat
14041 tgctgacata tattatttct ttttgatact tcgctgggaa tctcacagaa aggtggctct
14101 agaatacaga agaacaaagt acatagtccg taattgatgt atgaagttaa tgggaaagta
14161 cgaatggtac tgtccactca agtaatactt tgagattgaa atttgaagct ttttcaagta
14221 aataccataa tgataccaac aatgatacct acaattttaa atatcgtaat tgttaacttg
14281 atttttcata atctcattta ccgacttgca atactaaacg ggtaccagca gacaatagaa
14341 aaccttctca tttgaaatga attctaattg tgaaggcgga aatgcgtact ttgaggaacg
14401 tctattgtcg tataaaagtt ttacaattaa ctaagccaat gtatgatacg cccgcttggc
14461 ggctttttct ttccgactat ataaatgcaa atagtcagaa gttgtaactc caataacaaa
14521 cccctcatac cgtcctcaaa ttggcatatc gctatcagaa tgagaggcga tggggttaaa
14581 gataggagta tagatgtgtt atccctcaaa catttcgaat cccagaaagt tgttctgcct
14641 caagaccttt tcatggataa cttcacctgg atgttttatg agttcttcaa gtgcttcacg
14701 tttcgtacct ggttgctatt attactgcta atgtggttgc caggttttct ttcgcagata
14761 aagtccatca atcggatttt tccgtttaaa ctttgtattt tagtctcatg cctagtgggg
14821 atatttttac ccaatattta ttcattctct cataaaagtg tgttaacgaa tcaacttact
14881 cagttctcca aagaaattgt tgaacatgca ccaggtactg atactcatga ttgggaaaca
14941 gttgcggcaa atctaaattc ttacttctat gaaaataaag cttggaatac tgagtacttc
15001 tttttcaatg ctgcagagtg tcaaaaagca ttcagaaaag ttcttctcga accattctct
15061 gtgaagaaag atgaatcttc gaaaataaaa tcatttgggg attctgtccc ctacatcgaa
15121 gaggccttgc aagtctattc cacagaattt gacaaaaagt ggaagttgtt caatactgag
15181 aaagtgtgga gccctgataa cttggaacat gttcagctcc ccaagaaaac ttatcgttat
15241 aagtttacct gggttctcaa gaggattttc aatctctggc tttttccagc atttattctg
15301 tttctggctt gtatctatgt gtcatgggat aagggccatc tatttcgtat cttgtgttgt
15361 gggggaggtt ttctccttat ggtaagagtt tttcaaaata tgaggccctt ttccatgcac
15421 atggaagaca aaatgcagtt cttgtcaacg attataaatg agcaagaaag tggtgcgaat
15481 ggatgggacg aaattgcaaa gaaaatgaac aggtacttgt ttgagaaaaa agtctggact
15541 agtgaagagt ttttctttga tgggattgac tgtgaatggt tttttaacca cttcttttac
15601 cgccttctat ctacaaagaa acctatgttt gatagacctc taaacgtgga actatggcca
15661 tacattaaag aagcgcaatt gacccgcaaa caggcgcctc ccgtgtagga acaagcatgc
15721 cttttcaatt tatagatcgt gtagtttatt agatgcgaat agcctaaaca aggtcgctta
15781 ttattattat tacaactatt ctttttccta ttcccctctg gttaacaaaa accagtatat
15841 taacagaaat aaataataat aacaaaaaaa tatgaatata agaataaatt gcaataaata
15901 gtaatattta taaaatataa aaagaagaaa tttttattct ttttatattt tattataaaa
15961 tagttcaatt atttatatta tttaaatgtt gtaatttatt attaataatt atattttatc
16021 aatatttata cgatataaaa atttaaaaaa attataatat agaaataata aataataata
16081 atatgataat aaaataatat ataaataaaa atgataagat tatattaatt tatttaattt
16141 tcaaattatt aaataaataa taacctaata cttacttttc ctaatattat taaaaatggt
16201 tattgtcaaa cccattaact gattatatta taatatttca atatttaatt cacttaattt
16261 gttgttataa taattaatga aatagagaaa ctataatcca attgattgtg caacagtttg
16321 atcttccaaa tcataaaaga atattgagtg ttagttggta ctggtcataa ctatccattt
16381 tgaacataac catgtaactc ttttcccgtc tactgttaat caagggaaca tgttgaaagt
16441 tatatcaata catgtgttga gtatttcacg cgaatttatt gctacaaaag agcactaagt
16501 aatacatcgt taatttctgc ggtagaactg acctggtgac cttgcttgat gctttattgt
16561 ttgtgggatc tgtcacgtat atcgccatat ttttttccta cggatataat gtaaaacact
16621 aatttatcct tcagggttgc tctttaaaac tcaattgttg aataacttgg tattcatata
16681 tgtggctgct gcgaatatct tgacacatat tatgattatc aaaaaaaagt gaagaactaa
16741 atttaggagg atttctacag ttttggtctt ggttaggtaa taattcctta aaatagaggc
16801 ttatcctttc ctgtggacca taaatatctt catgcaagat ctcgattgat tagtaataag
16861 agcagacgat attgtgtgtg gaaaagagaa ttttttctgc gtataaaata ggacattatg
16921 acagttacct ttaattgaag tagagatatg ttttttcaac ttagaagcta tgtctttact
16981 gggtgtaagc ctaggaacgc tcttctgttt tagttcaaaa tatgcaaaag aaactaatat
17041 accagtaatg ctcatagtca cagtcagaag ttatattatt agtttgacat aagcagtatt
17101 cttccctctc acacactatc attctgccaa aaaattttcc cacataaggg tgtcagttca
17161 gtgaaatata atactagtag aaaaatatgt agagttatca gagtataaat cagctagagg
17221 ctttttttgc tgaactcact tcaaaatctc aaccatgtta ttaatgttaa gtcaaatgat
17281 atatgccgtg tgaaagtaga caactaaagc tttccaattc ttcactataa aactgaactc
17341 aaaattcaaa agtatacact aaatcgttgg gccatcttcc ttcccagaga ttaaagtagc
17401 atatctcttc atgtctacat tacctccact tagtattatg cctactttct tcccaactag
17461 ctcttccttt tttagaagtg cacctgcaaa tcccaaacaa gctgtgggct caacaaccac
17521 cttcatgcgt tccgcaagaa agtgcatgca ttttactagc tcttggtcgc taaccgttaa
17581 aatatcatcg acattttcgc gaataatggc aaatgtgtac tcaccgaggt gttgtgtttg
17641 agcgccatct gcgatagttt ttggcgtatt gatatgaaca atggaacccg atctgaagga
17701 ttgttgtcca tcgttaccag cttcaggttc aaccccaaaa attttgcagc ctggagaaag
17761 gcttctagcg gcaagtgcag atcctgaaag gagcccacca ccgcccaaag gaacaaataa
17821 tgcatcaagt tgtccaacct cttctaatag ctcttttgcc gacgtacctt gccctgcaat
17881 aacatcagga tgatcgtagg gcggaatcaa tgcaaaacca tgttcggctg ctagttgacg
17941 cccaatctgc tcgcgatctt cagtatacct gttatacctt atgatatgtg ctccgtaacc
18001 ggctgtagca gcaactttaa gggcgggcgc atcctcgggc ataacaattg ttgcaggtac
18061 atttaatagt tttgcactaa gagcaatagc ctgtgcatgg tttcctgatg agaaggcaat
18121 tactccctta cttctttttt catcacttaa ttttgaaaca gcattcattg ctccacgaaa
18181 cttgaacgct cccactcgtt ggaaattctc acctttaaag tatatttgtg ctccaagtcg
18241 atcattaagc attcgtgaag tgagaaccgg tgttttattt acatattctt taattctgtt
18301 gctggcatcc aaaacgtctc cataagtggg aacaatcatt tttccaactc aatgaaaact
18361 aaatatctcg aactatatta attatttgta ctttttaagt tttttttcaa tactccttta
18421 tttgaatttt tgcagaatga aaatgtaact ctttatattc caaagcttat ctttttctca
18481 cgtaccgtcc tatagaccct gattttatga taagaggctg aatttactaa ttagtcattt
18541 ttttcagttt ttttgtcata gaagccacat ttaaaagaag tcagccaagt tacctgtaaa
18601 tattaaaaca acctgcttag aatgactgtt aatttacaga atttacgata aaaatataac
18661 ttggctctag ggcgtgatga tagtgacaaa aaactcgtca agtaaatgtt gggagcttac
18721 ttgccgtcgt tttctaacgc caaaatacac gaatcatgtt tgggaaatat aagtgattag
18781 aacttgtcca aggatattgt caaacaataa catactacaa taatcctaga tcgtgtatta
18841 tttgcgtatg gataaatata cctcaagctt tatgaggcat agaaaattca ttagagtcac
18901 tacttacgtc gcactctcga ggattggaat gacgaaatct tcttcagcat ttcaccattc
18961 accttttgaa gcttcctatc tcgttgctta agtagaatga aagcatagca gcccaaaaga
19021 aaagcctccc tcagcaagaa tattaacaaa gaacaattca tggaccgttt ctactactta
19081 atatctctat cacaactgtc agtctcaatc agtacttaaa tgacgctgca gaaaaagata
19141 tcattatttt tatcatcccc ctaataaaat aagtaatgaa tcaatgccat taattcggga
19201 actagtcata tacctaagga atcaggcttt gatagctctt taataataat attagggcat
19261 ttttgatatg gtaaaagatt agattaggaa accccttttg tagagcatct cactacaata
19321 tctgcaaaaa cggtcacctt gcataggcag aacacgctac ctttgagtta attcacaggg
19381 gagagccctt tttttttctt agcaaaagtg cttaacaatc ttaatttctg gaatgttttc
19441 ggcggattgt tgtatattgt ttgaatttgt tcgttctaaa aagtgagaca cctgcacttt
19501 ccacgccaag aacactaata cctttaaaca tgccagcgta ctttaaaatg ccacgagtcg
19561 ccccgtacca aacatgctgg cgattgtaat ttttcgcctt ttattggaat cgagaattcg
19621 ggcactgtcc ttttcttcgt catttcaatg ttataatcat ttttatcgcc aaattttctt
19681 caataaaagg tctcttttaa aatatgttac tatgtttttt atttttctat tatttttcta
19741 tgtgattttt cagacgattt attctttgtt cgaaggagaa cagatgcaac ggtcaagttt
19801 ttactatcca catgaggagc cgtaatattc taaaggcaaa agcatgtgtg cttgtaaaaa
19861 aaaatcaaaa aaagttactg ctccaagcca gcaagctttc tcttttgcga aatctttaac
19921 acggttaaaa tcaaagacaa ttacttcatt gacaaggtca atgctaatat ttacggtctc
19981 cgcacgaaag actctgaaaa atgttaaaat ttatagtggc taatgctaat tcaagaatag
20041 tctcgggttg tttgatcaca ttattttaat ttttattgag cactgaatag gacccgtatg
20101 ttccaatcag tctatttctt gcaacttaat ctggtttgtt tttaggggag tggcattttt
20161 tttagggtta ttcaaatatt caattctgta atttgcttac gacaaaaaga aaaggagaga
20221 tgaaaaaagg gcgacgggta taatctattc agccgccaat gtcccgacgt atgccaaaat
20281 gtggtgccgc ggtaacagta gcatcacaca gagcatgaga aaagcaagaa aagtggaagt
20341 ctgtatgtca catttttatt gaaaatgcta tttgctataa ggttcgctat tcaactgatt
20401 gaaccgagat agacaaaatg ttaaactttt catagagacg ttattgtgat agggtttacg
20461 ctgagaatgg ttgaaacata cttgctaata aaccacgtca cgtcaaaata tcagtttttc
20521 ttttttagtt attcccttct cacttttgac ttgagatgag atcgttacac ttttattgaa
20581 tacgaacgga tcacgataca tccacatata cgaatgttcg gccagacagg gcatcagagt
20641 atataccctt tttcctaaaa tggaagggcc ctagatcgtt ggcatcagcg gttacctaac
20701 cgaagtggat caaatcagcg cctatttttc cgtttagaac gattagatgc cgtcaatatg
20761 tatgtgctta ctgtatcatc cacgtagtaa agctggggcg tagcatccct aggttacttt
20821 ctcaatactg gggtccctga ccaaagataa aacataacct attatggcgt acgagtcaaa
20881 gttaaacgct atttgactcg ggcagcatgc atgacccggg ggaatggaaa acttctcatg
20941 gctaccccaa cgaagccaga caagatctag gagatgtctc caccttccga gctacactct
21001 cacatctctt acatagacac tgtgaagtaa gtgattgcac acaatccaaa gaagcacatc
21061 aaataatatg taaatattac ccgtacaaat ggcaaatcat gtccactttc ccgttagtca
21121 tcgggtgggc cggtcctcgc actttccttt tgtttcggat gttaattaat atataaatgg
21181 atctataatt ttcaaaaggt ataaacgcac agtatgaaaa atattgcaag aataatgtgt
21241 ttataaatta ttttttttgc tggtagcaaa atcaactcat tgtcttccat tcagagtcta
21301 atcgaacgtt atcgcaatgc ttgcacactt ttaaacaata cgatttagtt taagtggatg
21361 gacccccacg cttagtgttc cacaggtttg tccccactgt ttttacattc cactgtacat
21421 ttttgcaata gaaggtcatt gtatgctacc ttgggcggct aagaatacct gtaaaaattt
21481 ggagaaatta gattcgtaaa gaatgactcg caacgactcc aatgatttct tcttttcacc
21541 ctttgaacgg ccgatatccg cgcgggatcc tgaccccgca atttactcca ctagaccggc
21601 gtgtttctct ttttcctttt cctggggtta gagcccaaga gctaatagcc gacaaacgga
21661 ctccaaaaaa aaaaggaggc acaggacaaa cgcagcacct gcgtcattca cgctgaagcg
21721 gcagcaagca ttttcgatca gctccaatta aatgaagact attcgccgta ccgttcccag
21781 atgggtgcga aagtcagtga tcgaggaagt tattgagcgc gcggcttgaa actatttctc
21841 catctcagag ccgccaagcc taccattatt ctccaccagg aagttagttt gtaagcttct
21901 gcacaccatc cggacgtcca taattcttca cttaacggtc ttttgccccc ccttctacta
21961 taatgcatta gaacgttacc tggtcatttg gatggagatc taagtaacac ttactatctc
22021 ctatggtact atcctttacc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa atcagcaaag
22081 tgaagtaccc tcttgatgta taaatacatt gcacatcatt gttgagaaat agttttggaa
22141 gttgtctagt ccttctccct tagatctaaa aggaagaaga gtaacagttt caaaagtttt
22201 tcctcaaaga gattaaatac tgctactgaa aatatgtcgt cgtcaattac agatgagaaa
22261 atatctggtg aacagcaaca acctgctggc agaaaactat actataacac aagtacattt
22321 gcagagcctc ctctagtgga cggagaaggt aaccctataa attatgagcc ggaagtttac
22381 aacccggatc acgaaaagct ataccataac ccatcactgc ctgcacaatc aattcaggat
22441 acaagagatg atgaattgct ggaaagagtt tatagccagg atcaaggtgt agagtatgag
22501 gaagatgaag aggataagcc aaacctaagc gctgcgtcca ttaaaagtta tgctttaacg
22561 agatttacgt ccttactgca catccacgag ttttcttggg agaatgtcaa tcccataccc
22621 gaactgcgca aaatgacatg gcagaattgg aactattttt ttatgggtta ttttgcgtgg
22681 ttgtctgcgg cttgggcctt cttttgcgtt tcagtatcag tcgctccatt ggctgaacta
22741 tatgacagac caaccaagga catcacctgg gggttgggat tggtgttatt tgttcgttca
22801 gcaggtgctg tcatatttgg tttatggaca gataagtctt ccagaaagtg gccgtacatt
22861 acatgtttgt tcttatttgt cattgcacaa ctctgtactc catggtgtga cacatacgag
22921 aaatttctgg gcgtaaggtg gataaccggt attgctatgg gaggaattta cggatgtgct
22981 tctgcaacag cgattgaaga tgcacctgtg aaagcacgtt cgttcctatc aggtctattt
23041 ttttctgctt acgctatggg gttcatattt gctatcattt tttacagagc ctttggctac
23101 tttagggatg atggctggaa aatattgttt tggtttagta tttttctacc aattctacta
23161 attttctgga gattgttatg gcctgaaacg aaatacttca ccaaggtttt gaaagcccgt
23221 aaattaatat tgagtgacgc agtgaaagct aatggtggcg agcctctacc aaaagccaac
23281 tttaaacaaa agatggtatc catgaagaga acagttcaaa agtactggtt gttgttcgca
23341 tatttggttg ttttattggt gggtccaaat tacttgactc atgcttctca agacttgttg
23401 ccaaccatgc tgcgtgccca attaggccta tccaaggatg ctgtcactgt cattgtagtg
23461 gttaccaaca tcggtgctat ttgtgggggt atgatatttg gacagttcat ggaagttact
23521 ggaagaagat taggcctatt gattgcatgc acaatgggtg gttgcttcac ctaccctgca
23581 tttatgttga gaagcgaaaa ggctatatta ggtgccggtt tcatgttata tttttgtgtc
23641 tttggtgtct ggggtatcct gcccattcac cttgcagagt tggcccctgc tgatgcaagg
23701 gctttggttg ccggtttatc ttaccagcta ggtaatctag cttctgcagc ggcttccacg
23761 attgagacac agttagctga tagataccca ttagaaagag atgcctctgg tgctgtgatt
23821 aaagaagatt atgccaaagt tatggctatc ttgactggtt ctgttttcat cttcacattt
23881 gcttgtgttt ttgttggcca tgagaaattc catcgtgatt tgtcctctcc tgttatgaag
23941 aaatatataa accaagtgga agaatacgaa gccgatggtc tttcgattag tgacattgtt
24001 gaacaaaaga cggaatgtgc ttcagtgaag atgattgatt cgaacgtctc aaagacatat
24061 gaggagcata ttgagaccgt ttaatcactt ttcattgctc tctagggcgt gttcgcttct
24121 ctatgtaact gcatttcaca tatattcata ttatagcctt tataacatta cataaaagac
24181 atgatatacg acatacttta aagttagaat ttttgttgta ttaattttct cgaagggatt
24241 agaatgtaag tacatttaaa tagcgccgca agaaacataa cagccgttaa cactagcaag
24301 atggtagatt actgtgtcta agaatttaaa ttgttttgct tgcttttgcc actataagac
24361 aataatagta atagaaaaga aatgttagtc gaacagcaaa ttggtaaaag tggaaaaaat
24421 tatttcgtta ttcattttag gccgttcaga aatatagcat tttggttctt gcactgaatg
24481 ggccctgagg acagtgtgcg gctggatagc catatacttc gacattactt ttcacctttg
24541 aagggggatg tatgcttata cacaatcaaa gctcggcctg tgcaggtttc actacataag
24601 cttttttacc atagaaatct tgcagaagga agtaagtatc aagatattac gtatcgcatc
24661 catagaacga tagcagaaaa atgcagtata tgataacgat atgcttcaca gctgcggccc
24721 atttggggaa aaaaggaaaa ggagcatcct cgatcttaca gatgtcgctt tttcctcttg
24781 aggtcattcc ctaaccttgg atccaagtca atctggtatc ttcccaccct aaatagtgta
24841 ttccccatgt aataagatcg gacgataaac ttcgaaacaa ttctagcctt ttttattaga
24901 tatttactct actttagatt tggtgatttt actaaatgtt atccttcagc cactacagcc
24961 tactttttct cactaatatg ttcttgaagc cattttcttc accgggcttt gccgaaggtt
25021 atttcacgat cttcggcatt cgccgaaaat ttttcaagat gcccatcacc aaaaaataaa
25081 aaaagcttta tatatggcat ggcatacgca tcgggaaccg gtattcttct cttggattac
25141 acagtttgga ctactagacg tttcaaatag atatacacaa ttactcaaaa aaaaattgaa
25201 cttccgtacc aaacatgaca gccagtttaa ctaccaagtt cttgaacaat acctatgaaa
25261 acccatttat gaatgcatcc ggtgttcatt gcatgactac acaagaatta gatgaattag
25321 caaactctaa agctggcgca ttcattacaa agagtgctac aaccttagaa agagaaggta
25381 accctgaacc acgttacatt tctgtccctc taggcagtat caactccatg ggtttaccaa
25441 acgaaggtat cgactactat ttgtcctatg tattaaaccg tcaaaagaat tatcctgatg
25501 cacctgctat tttcttctca gttgctggta tgagcattga tgaaaattta aatttgttga
25561 ggaaaatcca agatagcgaa ttcaacggta ttaccgagtt aaacttgtct tgtcctaatg
25621 tgcctgggaa accacaagtt gcttatgact ttgacttgac aaaggaaacc ttggaaaagg
25681 tttttgcctt tttcaaaaaa cctcttggtg tcaagttgcc tccttatttt gattttgccc
25741 attttgatat catggcaaaa atattgaacg agttcccatt agcttatgtc aactctatca
25801 atagtatagg aaatggtctt ttcattgatg tggagaagga gagtgtagta gtgaagccaa
25861 agaatggttt cgggggtatt ggaggtgaat atgttaagcc aaccgcgctc gccaatgttc
25921 gtgcatttta cactcgtttg agacctgaaa tcaaagttat cggtacaggt ggaattaagt
25981 ccggtaagga tgcatttgaa catcttctat gtggtgcctc tatgctacag attggtacag
26041 aattacaaaa agagggcgtc aagatttttg aacgtatcga aaaagaatta aaagacataa
26101 tggaagctaa gggttataca tccatagatc agttccgtgg gaagttgaac agcatttaat
26161 tatcggaatt tgaagaacta tgatgggaca agttatggaa gagtgttaag attcgtatga
26221 atattttatt attttgaaat tgcataaatc aaggatagtt ggtaaatgct aattccttaa
26281 tttttcggtg agtgcattcg caattggcat catacattag ggttcaatgt gctttaatag
26341 atgatgatac taaatactta tactttgaaa taacttaatc aatgtaaatt attgtcttga
26401 ttcatttata cttaaatttt tatatctcaa catatgatat atccttacat taagacttat
26461 tcaagaaaca tttttcaacg ataattatta gtaggctaaa aatggcatag gaaccagaaa
26521 ataatgttga agaaatgaag ccatctgttt aatatttggg gaaaaaagtg aagaaattaa
26581 cgaatatgtg catatatata tatatatata tatatatata tattgcacag gtgattttga
26641 tgtagaatgt agccttttcg aaagagtaat ttggttttat ctacagagtt ccgaaacatt
26701 gttaagtgcc tgttcttata taattaaact gtactttctg taaaagtcaa tttgtggctg
26761 gcgcatccac ggtataccaa tggttccgtg taattcgata ttgactaaga accaaaaaga
26821 aatgctttaa tccttgtatt gtccaaatcc cccaccacca ggggttttaa tgatgaatcg
26881 atcaccgggt tgagcgtaaa tcgtattttt accgccgaca ttgattaatg cgcctgtgct
26941 atgtcttacc cataaattct cacctctact accgtcttgt cctcccttta taccatgagg
27001 gccaatgaca cgacgttctg ataatataga tgctgttaca gccttccgaa attgaacatc
27061 ccttactacg ccatttccgc cagtatattt acctttgcct cctgaacctc ttctgatcga
27121 gaactctttc aacagaacgg ggtatctcct ttcaaatacc tcagtatctg tcattcttgt
27181 attggtcata ttcgtgtgta cagcgtctga gccattccaa ccacttcctc tccatgaatc
27241 tgcaccagcc cccgagccgc cacatatggt ttcataatat ccaaagcctt tgatctgctt
27301 atcggttttg ttaccagaat ttcctccagt tccaaatgta aagttgttac agtcaccttg
27361 agaatctgcc atgacgttaa atgtttttaa gattacatct gtcactcttt gggaagttaa
27421 tacattgcct ccgacaacag cagcaccgga tcgggggctc aagagggaac cagcaggaat
27481 ttttattgtt aagggtttta aacaaccttg atttaaagga atatcttcgc ctactagaca
27541 ccgtagacaa taaagaatcg cagaattagt aatagcctct ggtgcattta aattaccata
27601 aacttgggga gaagtgccat cgaaattaaa aatatactcc tctttttcag gtcttatgat
27661 aacttgtagt ttaattaagc ttccatcatc taagcgatct tcgccagaaa acttcgttgt
27721 gccaaaatgt tcaaccattt ttgcaagcat tttttttatg gattcagatg catttgtctg
27781 aattgcagcc atgtatttca atattgtagc cagatcatat tccttagtta atgacccaat
27841 taactgtatc ccttttgtgt tagctgcgac ttgcgctttt aaatcgctta tgttatcact
27901 aaatcttctt gaacctgagc agcctgggta tttgcctgga tcttctacga aaagcttgta
27961 aattaattct tcctggaaaa ttccctcttt gacaaccaat tcggaataaa ttgcggttcc
28021 ttcttcgtac aattctttgg aatttggagg cactgaaccg ggtagaatac ctccaatatc
28081 tgcatgatgg gctcttgaag ccacataaaa tatcaattcg ccagttgaag agaaagaagg
28141 agttattact gttatgtctg gtaaatgagt accaccaata tccggatggt ttgtgattaa
28201 aacatcacca ggctttaatt tgccttccca taacttcgcc tgtgctgata tgcaggttga
28261 cattgatcct aagtgaacag gtacatgagg agcgttagcg actaagtttc ctttagagtc
28321 gaatagtgca catgaaaaat ctaatctctc tttgacgtta gttgaaacag aagttttcct
28381 caattgagta cccatctgga gggcgatatc cataaaccta tgactgaaaa tagacaataa
28441 gattggatct atatcaagtt catatccgct tttagataat gtcttcgcag ccttttggtt
28501 gatcttgata aatatatgag agtttaaaat tgttgcttgg ctgtttggta aaataatatt
28561 tgtttgggta ccgtcagcca atatggctgg gccctcgata attgttccgg caggaagatc
28621 atcaattttg aagaccgcag tgtcgaccca tttgttgtca aaatatgctt tctgggtaaa
28681 actagcatcc tttgacacgt cggctttctt gaaatgggaa atttcaatca attgctcatc
28741 aaccgttttt tcttttctaa cgcctgattt cccaattgct cttatcctta tatcatcaat
28801 tataattcgt ttgtcatcga atgagaatcc gaactctttt ttatgagctt cagagaacca
28861 ttccctaaaa ttccattggt catcatattt ttgtaatatc atcaaactgg tttcagtacc
28921 ttcatatctg agatttaaat atctttccaa gactatgtcc tcccgagaaa acgactgaga
28981 taaaaggttt ttgattgaat ttttagaaag ttctaagaat ctttttttca ctttcaagat
29041 ggtctctggc tcacccaaga taaaagagca aggctcttgg ttttcttcaa taacatctgc
29101 taagaaaatg ccataagcgg acaagataga agaatatcta tgaattaaaa cagtgtcaat
29161 gcccaatgaa tctgcaaccg ctatggcgtg ttgcccgcca gccccgccaa aggaaactaa
29221 ccgatgctga gatactacat gtccttttgc ttctgtaatg gccctcacag gtcttgccat
29281 gcattcgtta gctactttga taaatccata ggcaacctct tccatggtta gatttgaatt
29341 cagatcctta ttgatgacat ctgttaattc tctgaatttc aaagtagtgg tttctaagtc
29401 aagtgattca tcctcattgg gcccaaaaat tttggggaag aactcaggaa ccaaacgtcc
29461 taaaaagagg ttggcgtctg taatggtcaa aggcccgccc tttctgtagg ctgcagggcc
29521 tggatcagca gctgctgaat cagggcctac tctgaataac ccgtttttcc atgacaaaat
29581 agaacttcct ccagcagcaa cagtatggat gtcaagttga ggagattgta tgatgatccc
29641 tgcggtaaca gtttcaaaaa catgttctaa cctcccatcg ccgtacctac tgacatcagt
29701 agatgttcct cccatgtcaa agcctattaa gggtatgtta ttatttttat catagcatgt
29761 actagaataa cctattacgc cacctgcagg accagataaa atagatttca aaccggaaaa
29821 ttttccccca tccactaaac caccatcaga ctgcatgaat tgaatgtggg tatcttctgc
29881 gtggctcaaa cctgcagaaa tgctattcaa gtacttttta attaccggag taaggtaggc
29941 atctgcgaca gaactgtgag ccctcggtaa aaattttatc attggagaga cttcagatga
30001 taatgaaaca tgagaaaacc caatctccct ggcaatatta ccaacaattc gctcatggtc
30061 tggaaaagtg tatgagtgta aaaatgctat cgcaatagac ttgattccgc tagcataaag
30121 cactttcaga atagatctta cgcttgattc atctggcttc tttatgaccc ttaccatttc
30181 gccactatta ccttccagga taccttcttg ttcattagga gacgatttgg taaaataagg
30241 gtcttccgag aaatcttcta aagtaactct ctcatctatt tcaactacag tgtcatataa
30301 tggcactacc ttttttatat ttaagttgaa gatatctggc ctggtttggt ctccaatcag
30361 caatgaatcc ttaaagcctt tcgtagtaat gaaggcacaa cgttcaccat ttctttctag
30421 agcgcagttt gtagctaggg ttgtccccat tcttaaactt ctcacattag agatgtctag
30481 aggaataccg cgaggaattg tcttgtgttc aagcacctcc aagagacgtc ttatgccttc
30541 aaggggagca tctggatagt ttttgggatc caccgacaag agcttgatga cagtatcatg
30601 ttcttgttta cctgtaccaa tattccccac acaatcagtg aaagttccac ccttatcgat
30661 ggcaattctt atgtttcctt tctgcattgt ataccaagaa gttatattta ggttttcaat
30721 gctcaaaatt attactgttt aagttcagtt cttagttttt ggcattcttt cttcaacacc
30781 acgtaacatt tgatcttatc tttcttttca gtggtaatgt tatggcgatc gtgctcaatc
30841 ggaaaagcac ctgaggcaaa caaaacaatt gttgaagtat tcatgcaaat aatactgaat
30901 agagcggagt acgcttgttc ttaattccag agattggtaa agtgtttatc attgctaccc
30961 tctagaaata aaaattaatt atttaggtaa aaagtagtac tgaggtttca tatctgtaga
31021 ctgatggagt aaaaaaacat tgaaaagact ataaagaaat tataagtaga tacacaattg
31081 cttaaccttt catgtaagca tctaattcag cgtcaagagc ttcgacagaa gtaggagtgt
31141 tattcttctc acggcccttg ttctttttgg agactctgtt aggcttttgg cgataatggc
31201 tccctggcct gcctcttccg tgttcttgag ccgtctgttt gcgacggttg tgggcattca
31261 ttctagaatg ctttctctgt ggttggtaaa tctccacttc aatttttgca ttatgtaact
31321 catgtccatt ataacgctcg acaatctttt ccaaaacttc tgggtcttca aattcgtaaa
31381 tacatgtacg atcctcttta ttgtcaaaaa ttttcgaaaa tattggcgag ccaaactctt
31441 taatcatatc atcgagggtg tagtcagaaa cgtctagtgg gattttggat attctaattc
31501 tcttaggcaa aggaggctct tccctctctc tataaaggcg atctttcgac cttgatgcag
31561 catccgaagg cgcaaatccc agtctaggtc ctaattcatt tcttaaatcc cttctgcggt
31621 atctcgttac cttatgatta gatgagctgt ctgtgtgact atttccaata atttcgtcaa
31681 atgctttgtc cattgcaaaa tgcagtattg aatcgtctaa tggaaaaggt actagacgct
31741 tatcgtttca gttttttagt cttttccatc tatttatcag tctgtactca aaataacctt
31801 attgtatgta acctttttca tttcacgatg ataatttctt gccgagttag acagaaaatg
31861 accgtgatag tttgtcataa ttttcaatag ggcagaaaga attttaaaga ttatttgcta
31921 tctagacatt atgtgtttta tatgattgct gtaaaagtat taggagagat cgtcgaaaat
31981 atccttaaac cttggcacgt tcccatagct ccttttgatg tttgcaagcc aagttacgga
32041 gttggcaaat tgtcttaatg taggttcaac agtagccaaa tttccgtaag ctacggttag
32101 cctatatgcg gcttcttcgc attcttgata ctcttccaat ggcccatact tggtgttgat
32161 ggcgtcagct acgataggca aaagttctaa atcagagttc cctttcgtga cgagagctga
32221 atagttgaaa attagtgtgg aaactgcaat agccaaattc tgtgactgtt tagcagatgc
32281 ctgagaaaat tcagtatcta tagtctcaaa aattgattta taaacttgat ttgattccag
32341 taatttcaca ccccagtttt cattattgaa gcaatttacc aaaatacgca cagttaacat
32401 ggttagagtg atattcttat tgcccaagcc ttcttcgatg taatctttta tatctgaaga
32461 ataaggtaat ttttttacaa tcaatcgtac tatgtcgtat gcaggagtct taatttccca
32521 gttagatctt atagtgttag caaatgaaag tagcaactcc cagctttcat ctatgtcatg
32581 tagtgcgcca ccaatttgcg ccagaatttc atcatcaaag gtcttctcat ttgaatttat
32641 ttttactatt ccattgaaaa tagtatctgg gttataattt tccatgataa gatactgctt
32701 gacaggaaga accttcatta cgctcgtttt tgaaggtgat actgcagaag atgatgcatt
32761 atcgttgggc tggtctagcg atatgccatt agtgttcttc agtatgaact gtactacttg
32821 atccctataa ctcattggca gttcataacg agccaaaaaa ttgtcggctg ctgtatatgg
32881 gttgtcgctg acattaatcg gcaatttcaa gggaggtttt ccatcttcaa tatccacatc
32941 aaatacgtag tcatacgttt taccctcgaa ttctattttt ttgtcgtttc cagtagcacc
33001 tgcaccgaca acatcaccaa cctttttcca tgaagaattt gaaaattgat gagcttctat
33061 agtaccttga ggtgatttga ctaccacaat ttgaccctct ttgcgccccg gcgattgtaa
33121 aatttcataa ggtgatagtt tagactcatc aaattctatt gtcttggaac ttatagtgga
33181 tttttccact tgcgtagata gttcatttat ttcatcctcg gaagcccatc ttgacttctc
33241 ttgcgaaaat attctcacaa gattatcact acttcccaca ataatatcac cattagacat
33301 acaatcaacg gaccaaatag agatggcagg aagtgtaatt acctgcttta acgaaccatt
33361 ttcctttgac catatacgga ctgttcggtc ttcgccgcag cttacaatat ctccattggg
33421 cagcagttta atgcaataaa caaagctttc atggccttca tatgttctta gtacgtcacc
33481 tgtatgcata tcaaccaact tgatgaggcc atcgtttgaa caactgataa aatggccatc
33541 atccaccaca gctaaatgtc ttactacatc attgtgaatc ccactgaaag ttttgatcac
33601 tttatcgttt tgccacagtt taatcgtctt atcggcggaa gctgtcaaga atttattttc
33661 tgagaaggat acgactttgg catcccatac agaggcattg tgtgcttgca aattgtaaac
33721 caacgatcct tctttccaaa cctttgcggt tttgtcccaa ctaccgctta tcacaacacc
33781 atcttggaag gataaactac aaacgttccc ttggtggcca atcaaggtat acaagggatc
33841 ctctcctgag gtggcaaaca agggcacacc gttgatcata gtatccttac ctccaaaaag
33901 caacaactcc ttctcggaat cataacacac actatttaaa aatccttgtc ctgtataaac
33961 taccgtaccg agccattggt catctttaga ccacaagcga actgttccat ccctcgaaac
34021 actagcaacc tttgaatcat ccacagctac cacatccctg acgtcctgat cgtgcccttt
34081 aagtgttgca ctcaattgat atcccatact ccaaatctgc tgctctacac cttactatca
34141 cacatgaata tatatatata aaataagcca agacagtggc cttcccttat tatcagcgta
34201 ctaaaatctc atatgattta tttttcgtgg tcctgaacga gtgtgaaaaa ttttgaaaaa
34261 ctcgcaaagg aaatgccaag gtcagcaact ttctcgacgt ccaagcctcg ctcctattgt
34321 tttagtaacc tgtagacctt caatattcaa gagcttgcac acgcacgcat tgctgcacta
34381 ctgcttaccc acactacaaa tttaattcca gcttattgaa gttgaaaagg caagggaaaa
34441 ataccacagg tttagataag gaaataggag aaaggattag aaaccatatc cctataacag
34501 taacgataat atttatatac acgtatattt tctcgtctag atatgacagg tccaatagtg
34561 tacgttcaaa atgcggacgg tatcttcttc aagcttgctg agggcaaagg aactaacgat
34621 gctgttattc acttggccaa tcaagatcaa ggtgttcggg tccttggagc agaggaattt
34681 cctgtgcaag gtgaagtagt aaagattgcg tccttgatgg ggttcattaa gctaaagttg
34741 aacaggtatg ccattatcgc aaatactgtg gaagagaccg gtagattcaa tggccacgtt
34801 ttctatagag tgttgcaaca ttctatcgta tctaccaagt ttaactcgag aatcgattct
34861 gaagaagccg aatatatcaa gctactggag ttgcatttga aaaattccac cttttatttt
34921 tcatacacat atgatttaac aaattcctta caaagaaatg aaaaggttgg tcctgcagcc
34981 tcctggaaaa ccgctgatga acgattcttt tggaaccatt acttaactga agatttgaga
35041 aactttgctc atcaagatcc tagaattgac tcctttatac aacctgttat ctatgggtat
35101 gccaagacag tggacgccgt tttgaatgcc acccctatcg ttcttggttt gattaccaga
35161 cgtagtatat ttagggcggg cacaagatac ttccgtcgtg gtgttgacaa agacggtaac
35221 gttggcaatt tcaatgaaac tgagcaaatt ttactcgctg agaatccaga gagtgaaaaa
35281 atacacgttt tctccttctt acagacaaga ggatctgtgc caatatactg ggctgaaatc
35341 aacaacttga agtacaagcc aaatcttgtt cttggagaaa actcattaga tgcgacaaaa
35401 aagcattttg accagcaaaa ggagttatat ggcgacaact acttggttaa cctagtcaac
35461 caaaagggcc acgaactacc cgtgaaagag ggctatgaat cagtcgtgca cgcgctaaac
35521 gatccgaaga ttcactacgt gtattttgac ttccaccatg aatgtcgtaa gatgcaatgg
35581 catagagtga aattgttaat tgatcacctg gagaaattag gtttatctaa cgaagatttc
35641 ttccacaagg tcatagactc taatggtaac accgttgaaa ttgttaatga gcaacattcc
35701 gttgtaagaa caaactgtat ggattgtttg gacagaacaa atgtcgttca atctgtttta
35761 gcccagtggg ttttgcaaaa ggagtttgaa agtgccgatg tcgttgctac tggaagcact
35821 tgggaagaca acgctccatt gttaacttct taccaaaact tatgggctga taatgcagat
35881 gcagttagtg tggcatattc gggcactgga gctttgaaga ccgatttcac aagaaccggt
35941 aagcgtacac gtctaggtgc attcaacgat tttttgaatt cagcatcacg ttattaccag
36001 aacaattgga ctgatggtcc aagacaggat tcatacgatt tattccttgg tggatttaga
36061 ccacataccg cttctatcaa gtcgccattc cccgacagaa gaccagtgta tattcagctg
36121 atcccaatga tcatttgcgc agccttgacc gttttaggtg ctacgatatt ttttcctaaa
36181 gatagattta ccagcagtaa gaatttgctg tattttgcag gtgcgtcgat tgtcttggcg
36241 ctttcaacca aattcatgtt taagaacggt attcagtttg tcaactggcc taagttagta
36301 gacgttgggt tcttggtcgt tcatcaaacg catgataaag aacaacaatt caaaggtttg
36361 aaatatgcac agagtcctaa attttccaag ccggatcctt taaaaagaga ttaatgagtt
36421 ctatatgtga taaaatgatg attattgtaa atccaaaacg taaaaccgaa aatatgataa
36481 aaacgagaaa aaaagtaagt taaaaaataa aaaaataaaa aaatgaacgc cggccccaga
36541 gggaagaaca agctatttat tttctttttt actttatctt tcatggtcat atatatatat
36601 atatatatat atatatatct tctataggct actatacatg aaggcgttcg cccttacaac
36661 gttaagtttt tttccctatt gtaccgtgta agtttcaatt attcgcataa ttcatgaatg
36721 aacttcttca catcggttga tttcattagg gcttcaccca ctaaaaatcc atggacacct
36781 tcttttttgt atttttcagc atcgtccctg gtggtaattc ccgatagagc aattagaaga
36841 acatcctttg gaatagattc taccaagtta ctggtggtat ttaggtctac gttgaatgaa
36901 tgcaggtccc tattattgac acctacaact ttagcaccaa tttctagagc cctttgtaat
36961 tcctctttgg agttcacctc aacgagaggt tccatgttca aatctttact gtagctgtac
37021 agttccttca ataagggttg agatagcatc ttgactataa gaaggacagt gtcagctcca
37081 gctaatcttg cttctagtat ttgatacttg ctgaaaataa attcttttct caaaacacaa
37141 ggcctctcct tgggaggaaa tttcaaatct aggattttcc tcacatttac taaatcctgt
37201 aacgaaccgt gaaaccaatg aggttcggtc aatacggaaa ttgcggatgc accagcctct
37261 gcgtatttga gagcctgttc agcagcaaca gcttttaaac aaatgggtcc cttcgatgga
37321 gaggcacgct tgacttcagc aagaacaacg gctcttttat gggatgatga caacaccgtg
37381 tagaaatcct gtaacggtgg ggcaagacct aaatcatagt tagattgtaa gtcttgaaag
37441 gtgaaacctg ggattttaga ctgctcattg acgtctattt tacgccgagc atagatacgg
37501 tccaaaatag aatttgaagg agatgatttg ttttcctccc aagtgcctcc actgacgttt
37561 aaaatgttcc tgatcatcag atgaccttcc tcggtcaaga tggattccgg atgaaattgc
37621 acaccttcta cagtgtactt cttgtgtctt acacccatga taattccatt ttcggtactc
37681 gcagtaacct tcaagcagga tggtagggac gattctgtcc cggccaatga atggtatctt
37741 gtcacagcaa taccttgcgg cacgttcttg aaaattccac agttgtcgtg agagattggg
37801 gacgttttac cgtggacaat ctcaccagcg taggcaactt caccaccaaa tacgtcaaac
37861 atgcattgct ggcccataca gattccaaat acaggaattt tcccagtaaa gtaccggata
37921 cagtctcttg aaatgccaga atctgtcttt gggtggcctg gtccaggcga gataagcaat
37981 gtgtcgggat tcaaggcggc aatttctgga actgtaattg catcgttacg gtagacgctc
38041 actttggcgc cctcctggca caagtactcg taaacgttcc aggtaaagga atcgtagttg
38101 tcaattagaa ccacatgctt attgattggg tttgttgcag cgtgcacaga catttttttc
38161 ttacttttat ggcgttctat gtagaaccaa acagatttgg taatgtgtta atactgacca
38221 gctccttgtc gaactttttg cgtaccttaa tatctgctat agattagaat gagtcaacga
38281 gccattgatg atcattcaat gattactaca agaggcattt tccgtcgtca gtgatatgaa
38341 tagcacggtg aggtccagaa gagatagtag gaagtttaat actggctcaa aggcatactt
38401 atatcgacaa gctaagcgca aatactactt tgtggtacat catcagcatt gctttcgaga
38461 aaacagcatt taaaatcagc catttgctgc gctttcttta agccctaaca gaaaatagtt
38521 caaaaaggcc tataagaagc aaaaaaagtg aaaaatacga aaaaatactc cagcggagga
38581 gtataaaagg gaggaaaata caaaatgtag ttgtgttgtt acgcatctca aagaagaaag
38641 aagaagaaga agaagaggac gtcgcacttg caagcaaaaa cagcgactgg cgcgagaaca
38701 acaaacacta atgcatgtct ctgtccagca ggaaaagcga gccttagtgt ttcttatttt
38761 ctcgttcgcc tcactagttt gtagtagggt gggagaaacg atggagtgga ttgtatgatg
38821 aggaaccaga tagggacaac agattctcaa gtgacgagga acatctttta aagcccagtt
38881 tttagtagag cttagggcgc ctttactgac tatccactcc ttgttaagct atgatcttgt
38941 attcatgtga ttgtaaataa tattagagct ctttcttgaa ttgccattac gcttccatgc
39001 ggcatattct cgtgtagtgt gacaaaaggt gcgggtggca aataaaggta aaagaaaatg
39061 atcaaaaagg gcctttaagt aggatgagca accgccaatc gctggatata agcaaacaaa
39121 aagtaagatt agtagcaaag caaagaacat ataactatag ctatgagcag caataatagt
39181 ggtctctctg ccgccggaga aatcgatgaa agtctttatt ctcgtcaact ttatgtgttg
39241 ggtaaggaag caatgttgaa aatgcaaacc tccaacgtat taattctcgg cttgaagggg
39301 ctaggtgttg agatagcgaa gaacgttgtg ttggcaggtg tcaaatctat gaccgttttt
39361 gaccctgagc cggttcaatt ggcagactta tcaacccaat tctttttgac cgaaaaggat
39421 attggtcaaa agagaggaga tgtgaccaga gccaaattgg cagagttgaa cgcatatgtc
39481 ccggttaatg tgctggattc cttagacgat gttacccaat tgagtcaatt ccaggtcgtt
39541 gtcgctacgg acactgtttc tttggaagat aaggtgaaaa tcaacgaatt ttgccattcc
39601 tccggtatta gattcatttc ctcggagaca agagggctgt ttggtaacac cttcgtagac
39661 ctaggtgacg agttcacagt gttggaccca acgggtgaag aacctcgcac tggtatggtt
39721 tcagacatcg agcccgatgg aacagtgacc atgctagatg ataacagaca cgggttggaa
39781 gacggaaatt ttgtcaggtt ctccgaagta gaaggtcttg ataagttgaa tgatgggacc
39841 ctttttaaag ttgaggtttt ggggcccttt gcattcagaa ttggttcagt caaagaatat
39901 ggcgagtata agaagggcgg tatcttcacc gaagtcaaag taccccgtaa aatctcattc
39961 aagtctttga aacaacaact gtccaatcct gagtttgttt tttcggattt tgctaaattt
40021 gacagagctg ctcaattgca tttgggattt caggctttac atcagtttgc cgttagacat
40081 aatggtgaac tgccaagaac aatgaatgac gaagacgcca atgaattaat caagttggtc
40141 accgatttgt ccgttcagca accggaggtt ctgggtgaag gtgtagatgt taatgaagat
40201 ttaatcaaag agctttccta tcaggcaaga ggtgacatac cgggtgtcgt agcatttttc
40261 ggtggccttg tggcacaaga agtgttaaaa gcatgttctg gtaaatttac tccgctaaag
40321 caatttatgt actttgattc cttggaatca ttgccagatc ctaaaaactt cccaagaaat
40381 gagaagacta ctcagccagt aaactctcgt tacgataatc aaatcgcggt tttcggtttg
40441 gattttcaga aaaagattgc caattcaaag gtctttcttg tcggatctgg tgccattggt
40501 tgtgagatgt tgaaaaattg ggcacttttg gggcttggtt ctggctccga cggttacatc
40561 gttgttacgg ataacgattc gatcgaaaag tccaacttaa accgtcagtt cttgtttaga
40621 ccaaaggatg tcggaaagaa caaatctgaa gtagcggcag aggccgtttg tgctatgaac
40681 cccgatttga agggcaagat aaatgctaaa attgataaag tggggccaga aactgaggaa
40741 atatttaatg actccttttg ggaaagcctg gattttgtca ccaacgctct agacaatgtc
40801 gacgcaagaa catacgtaga tcgccgttgt gtgttttata gaaaaccact gttagaatct
40861 ggtaccctag gtactaaagg taatactcaa gtcatcattc caagattgac tgaatcatac
40921 tcttcttcta gagacccacc agaaaagtct atcccattgt gtaccctacg ttctttccca
40981 aacaagattg atcacaccat tgcctgggcc aaatctcttt tccaaggtta cttcactgat
41041 tccgccgaaa acgttaatat gtacttgaca caaccgaatt tcgttgagca aacactaaag
41101 caaagcgggg atgtcaaggg agttctagaa tccatctcag attctctatc tagtaaacca
41161 cacaattttg aagattgtat caaatgggca aggttagaat ttgaaaaaaa attcaaccat
41221 gatatcaagc agttactgtt caacttcccc aaggatgcca agacttccaa cggtgaacca
41281 ttttggtccg gtgctaagcg tgctccaaca ccattagagt ttgatattta caataacgat
41341 cacttccatt ttgtcgtagc aggtgctagt ttacgcgctt ataattatgg tattaaaagt
41401 gatgactcta attctaaacc caacgtggac gagtataagt ccgtcatcga tcatatgata
41461 attccagaat ttactccaaa tgccaatttg aaaattcaag ttaatgacga tgatccggat
41521 ccaaatgcca acgcggctaa tggctcagat gaaattgatc agctggtatc atccctacca
41581 gatccttcta ctttggctgg ctttaaactg gagcctgtag atttcgagaa agacgatgac
41641 actaatcatc atattgaatt tataacggct tgttctaact gtagagctca aaactacttc
41701 atcgaaactg ctgatcgcca aaagaccaaa ttcatagctg gccgtattat tcctgccatc
41761 gcaacaacca cttctttggt tactggtttg gtcaatttgg aattatataa actgattgac
41821 aacaagacag atattgagca atataagaat ggctttgtta atttagcttt gccatttttc
41881 ggtttttcgg aaccaattgc ttcaccaaag ggagaatata acaacaagaa atatgataaa
41941 atttgggata gatttgatat caagggagat attaaattaa gtgatttaat tgaacatttt
42001 gaaaaagatg aagggttaga aataacaatg ctttcttatg gcgtttctct tctttatgcc
42061 tcatttttcc ctccaaagaa attgaaagaa agactaaatc taccaataac tcaattggtt
42121 aaattagtga ctaagaaaga tattccggca catgtatcta caatgattct cgaaatttgc
42181 gcagatgaca aggaaggaga ggatgttgaa gttcctttca ttaccattca tctatgagta
42241 actaattaac caaaataaaa aaataaatta aatatataca ttaaatatgt atatatatat
42301 gtatgacttt tgacaacttt ttctttggta aaaacttatt attattatta ttattattat
42361 tattaatgta gtctcgaata tttgagtatg ttttagtttt ttgttttata ttttctttgg
42421 gtttaactgc tttggttgga aacaatttgg aataattccc cgcgattatt atataaagtg
42481 tcgaagttac ctcgctcaac cactttacca tctttaagaa ctgcaatcga gttacaagac
42541 ctcatcattt gttcactatg cgttataacc attgttagta gagcaggtgg accttttttg
42601 acgatctcat tgatgataga ggagctgaca gaatccaagg ctgaagtaca ctcatctaaa
42661 atcagaattt ttgattttct cagaagtgct ctggctatgc aaagcctttg cgcttgtcca
42721 cctgacagta aagttgtatc aatacgtgta tccaagccct gaggtgatga aattacaaag
42781 tcatggattc ctacgtattt taatgcatca tacatttcaa tttcaagtat ttcatcttgt
42841 aaaccataag ttaggttatc tctgatggtt ccattgaata ataaaggttt ttgctcaacc
42901 actgaaattt cttttcttaa acttgtcaaa ttccagtcat ttacgtccgt accgtctatt
42961 ttaattttgc ctacttcaca attataaagt tttgttaata aaagcacaag tgtagacttt
43021 cctgtgcctg attcaccaat gatacctaac gtctgtccgc aaaacatgtc aaaattcatg
43081 tttttgtaaa caaaggcggt aggtgcagat ggataggcaa atgtcaaatt ttgaattgaa
43141 acgattggtt ttttttcttt gccatggtag gtgtgaccag ctattcccac tgttctagca
43201 ttattgtttt caacctctag ggtattatgc ttttcatcaa gaatcctata gatccaactg
43261 gcagcacgtt ggcctctact tatatcgggt atctgactta ctaggctagt gcatgacata
43321 atagtgaata ataacaaagt gaaagtcgta aacatttcct ttgaggtgta ctcgtgaatc
43381 ataaccagct ttaggccata gtagtaaata atagcttgga tacacatgac aatcatgttt
43441 gtcatagata taccaaatcc tgtggcaatg gcgcgtttgg aggcaatttg ttgcattttt
43501 atcttcaagt catggtaggt caattgaaaa tgaaattcag cttgtaagca cttaatggtt
43561 ttaatgttag tgacaatctg gtacaggcag ttttctaact gagcaacaga tgtcttataa
43621 tctgtttcgc atttttgtaa aatgcctcca tatattgctg aaaatataat tatgagtgga
43681 aacatcgaaa tacaaaccaa acttaacttc cagcccgata ctaacgccca aattagtcca
43741 atcgttgata cggtaacgaa actagtcatt gcactcaaaa attcagagac caaagacctc
43801 aaatctcgca aatcattcaa gactagagca gaaatttcag aagccttgtt gttttcacca
43861 gaaaaccagt ccatattctt tctcgtcagt ttttccataa cttcatttct aagatccata
43921 acccagtatt cactgcagca atctaatagg aatcctttag caaaattgaa aataccatct
43981 gccgcagcca caccaagaac aagaagcgac catttcgcca aataatgtga agagccagtt
44041 tttccatccg tggatgggac aattccttct agtaagaaac tgaatgtgta tgaaaagacg
44101 ggatttgtgg cgcctgcgat aagagaacat agcagtccca agattagaat ttttttgtat
44161 cttatgcttt taatcattct tttgataatc tgaataatgc tcagaagttg tggccctgtt
44221 gaactttcgg tgttcttttg ttgttttagt gcatacccaa tattttcctc ttcaacttta
44281 acccttcttg ttctaacgtt cgatcttttt tgatagattg cttcgtaaaa ggacaactga
44341 tctgtctcat catatcccag attacttaag catgatccaa gttttggtgt ttccaattga
44401 gagttaaaac tttccacagt gtgtatagat ttttcttcag tctctgtatc tacaatagtt
44461 ttcgcatcag agtagtcatt ctgtaggtga taccatgtgc taaatgtagt ggtcggatcg
44521 gctagaagtt cagactgggt gccgctttca acaacttcac cttccttcat taaatataaa
44581 tagtcatcag attcaatttg gctcaactca tgcgtcaata tgattgtagt ctttcctttc
44641 ctccaatgcc taattgcctt catcaacagg ttgcgatgaa caatatctag agccgataca
44701 gcttcgtcta agaataatat tggagtatct ctgatgaatg cacgtgctat agcaactctt
44761 tgttgttgcc cgccacttag tgtgacaccc ccagtcccaa ttaatgtttc cagtccatcg
44821 ggaaggtcta gaataaatct atccagaaga gccatttgac aggcatcttt gattaaatgt
44881 ctattttcat tggtgctgca atcggcattt cttaccgaat ctgttgaacc taaaagaata
44941 ttttttctaa gagtatcatt aaatagggta caacgctgtt ctacgacggt gatattttca
45001 attagcaatt tttggtcgat tgtttggata ttgtggccat tgatagatat cgatccatta
45061 tagccatcgt agaaccttaa taataagttg gataatgtag atttacctga gcctgatttt
45121 cctactatga aagtaaattg tcctgcagag aaatttaaac taacgttctt taaaactgct
45181 tccgaaggtc tgcttggata agaaaacgaa acattagcaa atgttagatc actggtggca
45241 taatctagtg gaaattggtg ggctacagtt ttatttaaag gatttcgctt ggatccatct
45301 tttaatagag tcatgatttt ttccatagcc actccgcctt tttgaagaac aactatttgg
45361 tgtaatgtat tatttaaagt cgagcccagc ataatgcatg aatggaagca agtgattaca
45421 tcgttaatgt tcagcttgcc ctttttgatc attgcggaac caaaccagaa tccctgtaca
45481 aacatagtca acgtcaaaaa tctcaagatc ccagcgtttg cagcaacaaa aaagcaactc
45541 ttgatgaaga aagtgttaca atttagtatg atttccttga attttttcct ttctagacgt
45601 tgtgtacaat ataatctcac taattgagcg gcattcatcg accatgtaag taattgggct
45661 gctttactcg tttcagaatt ctccttctct gaatatacat gaatcattct ggaaaacacc
45721 actgcaaaaa atgtgattat tggagagctg caaagaataa ttaaagttaa tgaccaagaa
45781 tagtagaatg acgtccccag aagcgcacat attgcaacta aattctggaa agttatggct
45841 gatgcctctg cggagcttga tcttagctct tccacacatc tgttgatttg agtaaaatct
45901 cctaacaatt tttcattatt gtcgtaccat tccattggct tttcctccaa atatgcctcc
45961 aatatctgtg accgtattct aaagccttgt ctctcgccga tgtgcatcca acttgttaga
46021 gaaagccaca ttactggcac agaagccgca ccaagtgcca ttactgccat tgacctctgt
46081 actagttggg aatacaaacc ttgatgtgac ccattagcca cgaaaactga tagtagatcg
46141 aacactctgc ccgtcaggat agaagtaatt gccggcacta ggcctgttgc cacggtacct
46201 attatcatta tcattaacag cctgtagtca ttccgtatgt tcacgtacct gaaaatgtga
46261 tagtgttttg tagtcttaaa acttaaaaag ttcatgacgt agcttgttct ttgtttccta
46321 gtggaatttt cagcggcact tgaaagctct ctgtgtgaac gtaacaacgg gagatagttc
46381 agccatatcc aggtttataa gctctggtat ttaaatgatg aacggcaata atgcaacagt
46441 tttcatatct gaaacaattg tatatgtgcg aagcagcgtg taaatttccc tattaggtaa
46501 ttacatggca aaaaaaataa gaaactattt tcttaaagta cctttaccct ttgtggaaaa
46561 caataaattg tatagtggca gaatagagaa aagaaaaagg aaaggaacat atttgtcagt
46621 gcaaggacca tcattgtttg aaaaaagaga ggatattact agtaggtaat aacagctatg
46681 tcgcgttata tatattatat ataaaaatta aaaaatagaa aataaaattt caaatgccct
46741 ctgtgggaat tgaacccacg atccccgcat tacgagtgcg atgccttacc acttggccaa
46801 aagggctgag taatttttat acctgctaaa tttgtggctc cgctatactt tacagattta
46861 tctattttga agatgataca tttagcaaaa atgaccttaa aaatgaagca ggtgccattt
46921 gcctatagct tggaaaagta gtaatggtta ttcaaaaagt tagcagcgag atcttttttc
46981 tatcgcgcgt taaaacgttt gaacagatat atattattca gccacaacta tctatatata
47041 atatttcttc gatttttcgt tttctcaagt ttcgtcttat tgattgatca gaagtttact
47101 gcgcttttgg gtaaagaagc attaaacaaa ggagagagaa atattgcaag gaaaaaatgg
47161 tgagctatgg aagtcatagt agtgaggttt cgaaagttct taaaacgccg aagtttgtgc
47221 ttaggtatgg aaatgtatcc agcaaacaac gttttgccct aaagcggaag ataaattaca
47281 aactacgtga aagcaaatat caagaatact tgaatgaata caacaccttc gtgctttacg
47341 actgggaaaa cagtggcgct ggtagtcttg tcgattcttc ctacaatctc ccctctttat
47401 ggaaggaatt cataacagag ggcatatcta aaggagcaat aaacgacaaa ctaccgacag
47461 tctttatgaa gaggaagttg acaaactcag cgttgggtca ctgtttggga cttgatttcc
47521 tgactgatcc gagcgagtca gaacatgaat acaggtgcat gtttcagaca gttcaggaca
47581 tcccatctct ctcgcaactg atcttattca acagcatgcc aaacgttcca gtaagattga
47641 aattgcatac cattggtata aatataaatt tcggctgcaa acgttccctg ataagcaacg
47701 gtggtgatca agacactgaa atgagcgaag cagtctctta tatccagcct ttattggaag
47761 aatcctcgag aatgtaccgc aatttaaact actggaagct gttaaaaata gcacgaaata
47821 acaagaagga tgaaccgttg gatcagagca cgcgtatcaa gtcgcaagtt aagcttttac
47881 tgagtcaatt ggcgacgaac cgaattacct caccttccgt cacggatcat gggggtcaca
47941 actggctcat attcaccaga agacggttgt aaacgataaa tatgccataa agatctgcga
48001 actgtacata tccatatata atgcgtatta tttggtgact atagcactgg cttccgccat
48061 ctcactaaga acgaagaggt ataataaagc attgtgatgt taaagaatga cgattaacca
48121 gcatttacaa caacttctct tcaacagaat agacaaaaca acaagcagta ttcaacaagc
48181 tagggcgccg cagatgttat tagatgacca gctgaagtat tgggtcctgt tacctatttc
48241 gattgtcatg gttttgacgg gtgtactcaa acagtacatc atgacactta taacgggaag
48301 cagtgcaaat gaagcacaac caagggtaaa gttaactgaa tggcaatatc tacaatgggc
48361 acaattattg attggaaacg gtgggaacct gtcttccgat gcatttgctg cgaagaagga
48421 atttctagtt aaggatctca ctgaggaaag gcacctagcc aaggccaagc agcaggatgg
48481 ttcgcaagct ggagaggttc ctaatccctt caacgatcca agtatgtcta atgctatgat
48541 gaacatggct aagggtaata tggccagttt catccctcaa actattatta tgtggtgggt
48601 gaaccatttt tttgctggat ttattcttat gcaactacct ttccctttga ctgccaaatt
48661 caaagagatg ttacagaccg gtattatctg tcaggacctg gatgtgagat gggttagctc
48721 catttcatgg tattttattt ctgtgctcgg gctaaatcca gtctacaacc tgattgggtt
48781 aaacgatcag gacatgggta ttcaggccgg gataggtggc cctcagggcc cccaaggccc
48841 tccacaatca caggttgaca aagcaatgca tgcgatggct aacgatttga ctatcattca
48901 gcatgagact tgtcttgata acgttgagca aagggttttg aaacagtata tgtaagttcg
48961 tggctatata tgcacttgta tagaaaacag atatacttct cggtttcaat tgtataaatc
49021 tacaaattta tctcttgcat ccgccattcc gtatgcacct tgccatgata taggcctgac
49081 aaactttaca attggtggcg cgtttttgat aactttttga gagattatcc attgtaagaa
49141 ctgttgagaa tctaatgagt tgtccccctc attggccaaa caactacagt acttaatgct
49201 gcggagggct ttaggcctct gcgacgcatt cagtatttgg aaaagtattt tgaagatcgg
49261 ctgatcaacg gatatcttgt cttggaaact ggtaggagta aaatgtaacc agttattgac
49321 catcgactct tgatcgttta gatggaggtt cgataaaagc tcagcttcat cgtcgaaata
49381 aaactctccg agcgaatata cctcctgtgg acgtacaatc acaccatttt catcctccat
49441 tgcatataga gagtcccaaa tgcatatttc cgatatatta tacttgctca agaacggcaa
49501 gatgatctct acgatgaaat tattcagata gttaacggac acgagtggtg ttcgttgctg
49561 tatggcaaaa agtcctcgct tcttattgta gaaaacttcc aaagcgctgc tatacttcat
49621 atcagcgtct ttatatagcg agtcgctacc atcctctggt ctgtctaatg gtcccacaaa
49681 ttccactagg tatttcgaat ctaacgcctc caaatattcc cattcatttg cttgtgaatt
49741 cagcagccag tcaatactca attgtggtat attccctacg cttactaatg gcaacaccag
49801 gcagctcatc gtatgttcct ttgggttttg tgctattctt tcctgaagtt ttaatttaat
49861 ttccttattt tagtgtaggt ggcttttttt ttagcaggtt actcattgtg ggatcatttt
49921 caggctcaaa gcgaaaaatt gaaaaattag ctaacaaaaa aaaactaaaa ttttttcaaa
49981 ttccatcagt tagtttgaga agttgtcggt aagcaaccta tagaacaagt gtttccagtc
50041 aaatcgagga atgctagaac ggattcagca gctggtaaat gcagtgaacg atccacgctc
50101 agatgtggcc actaagagac aagccatcga gctgctaaat gggattaaat catcagagaa
50161 tgcattggaa atctttatat cattggtcat caacgagaat tcaaatgatt tgttgaagtt
50221 ttacggactg tccacattga tagaattgat gacggagggc gtgaacgcta atccaaatgg
50281 tttgaatctg gtaaagtttg aaataaccaa atggctcaaa tttcaagttt tgggcaataa
50341 gcaaactaag ctgcctgact ttttaatgaa taagatttct gaagtgctga ctactttgtt
50401 tatgttaatg tacagtgatt gtaatggaaa ccagtggaac agtttttttg acgatctgat
50461 gagtctattc caagtggatt cggctatttc caatacgagc ccgtctaccg atggtaacat
50521 tcttctaggt cttgaatttt ttaacaagct ctgtttgatg attaattcgg agattgctga
50581 ccaaagcttt attaggtcta aggaatctca gttaaaaaat aacaatataa aagattggat
50641 gcgtgataac gatatcatga aattgagtaa tgtgtggttt cagtgtttaa aactggacga
50701 acaaattgtg tcacaatgtc ccggattgat caattctacc ttggattgta ttgggagttt
50761 tatctcatgg atcgatatta atttaattat tgatgcaaat aattattatc tgcaattaat
50821 ctataaattt ttaaatctta aagaaaccaa aatttcatgt tataattgca tactggccat
50881 catctctaaa aaaatgaaac caatggacaa actggctttt ctgaatatga tcaatttgac
50941 caacgaattg acttactatc atcaagccat atcaatgaat ccccaaatta ttacatttga
51001 taatttagaa gtctgggaaa gtttgaccaa gttgattact tcctttggca tagaatttac
51061 tatcattatt gaacaagtca acgatgatca aaaattggat acattataca aacaatcggt
51121 catttcaaat gttgattcca tattattgga gaaaataata ccaatacttt tggaatttat
51181 gaataatgag tttgattcaa taacagcaaa aaccttccca ttctggtcaa attatctggc
51241 tttcttgaaa aaatataaag catcttcacc aaattttgta ccattgcata aggattttct
51301 agataatttc caacaaattt gctttaaaag aatgaagttt tcagacgacg aggtcacaca
51361 ggatgatttt gaggaattca acgaaaccgt aagatttaaa ttaaaaaatt tccaggagat
51421 catcgtggta attgacccaa gtctgttttt aaataacatt tctcaagaaa tttcagcaaa
51481 cctaatgaat tgtaaaaacg aaagctggca aattttcgag ctaactattt atcaaatctt
51541 caatttaagt gaatgtacca agaacaacta tttcggtttg aacaagaatg aaattatgac
51601 ctcacaacct tcgctaactt tagtacgatt tttaaatgaa ttgttaatga tgaaggattt
51661 cttattagcc attgataacg aacaaatcca aatactattc atggaattaa ttgtgaaaaa
51721 ctacaatttc atattttcaa ctagtgctaa cacagcaaat gctactgatg atgatgaaaa
51781 gtatctatta atattgaata ttttcatgag ctcatttgct atgttcaata aaagagaaaa
51841 cgtcagacta aggtcatggt atttatttac aagattcttg aagttgacaa gaatcaattt
51901 gaaaaaaatc ctctttgcca acaaaaattt ggttaatgaa ataactaata agataagtcc
51961 tctacttcac ataaaagtaa catctatcaa cgcccaaggg acggatgaca atgatacaat
52021 ttttgataat cagttgtaca tatttgaggg tattgggttt ataatcacat tgaataatag
52081 cagtcaggag ctcactgctg ccactgccaa cacccccatc gattacgata tattggacca
52141 gatattaact ccgctattta cacaattaga gggttgtatt acccaaggag cttcgccagt
52201 tgtgattctg gaatgtcatc acattcttat ggctattggt actttagcga gaggtttgca
52261 cattggtctc gtccctgaga atcaggtcaa caatatggtt gtcaacaaaa aattaatcaa
52321 tgactcttta atccataaat tctctaatat agctgaggtt atattagtaa cattctcttt
52381 tttcaataag ttcgaaaata tccgcgatgc atctaggttt acctttgcca ggttaattcc
52441 aattttaagt aataaaattt taccatttat caataaattg attgaattga tcttatcgtc
52501 cacagattta aaatcatggg agatgattga ttttcttggg ttcttatctc aactgattca
52561 tatgtttcac acggacacag actgttatca gctgtttaac cagttactta ctccgcttat
52621 caacaaagtc cattctatta tcgaagagat tgatgaacaa cacgaccaac aatcaagcag
52681 taacaaacct atagacactg cagtcacagc cacctccgta aataagaata tcgtggtcac
52741 cgattcgtat agagataaaa tactattgaa aaaggcttac tgcacatttt tacagtcatt
52801 tactaataat tccgtcactt cgatactatt gtcagatata aacagagcaa tcctgccggt
52861 catattaaac gatttggtca cctatacgcc gcaagagatc caggaaacat caatgatgaa
52921 agtgtcactc aatgtattgt gcaattttat caaatgtttt gggaatggga cctgcttgga
52981 taatgacgac atcaataaag atcccaacct taaaatagat ggtctcaacg aatacttcat
53041 catgaaatgt gtcccaataa tctttgaaat tccgttcaat ccaatataca agttcaatat
53101 caaagaaggg aatttcaaaa caatggcata tgatttggca agattactga gggagctatt
53161 tatcgtcagc agcaacccca ccacaaatga gaatgaatgt gtaaaatatt taactcagat
53221 ctaccttcca caaatccaat taccacagga attgacgatt cagttggtta atatgttaac
53281 cacaatgggt caaaagcaat tcgaaaaatg gtttgtagat aatttcattt ctgttttaaa
53341 gcaaggtcaa tagctttcag gcgcagaaaa cctgaaaata aaaaaaaaat gcaaaacgag
53401 agtaaaagtt gtaattatat ttatactaat atttaaattg gtaatatgta attagactta
53461 tcattcactt tggtttagca gctagtcatg taatggcact aaaagtgctt ctttatctat
53521 tatttatacg tgacatacca ttacttctat gtattacgta aagaatgaca aacgtttagt
53581 ttttttaatt tcaaagaaat cgttggaagg ttcaaaaagg atcaggtgag atattagagt
53641 atatgaatgt ttcagtctct aagctacaca aagaactagc atagtaggac tttaacccat
53701 acaatggaac tcaacgaccc ttcaattata tcaagcagcc agttttcagg tgaattgtct
53761 gacagcgata ctgcagccgc tactcacaaa tcgcaacaag ccatctcaaa tttattccaa
53821 aaattagcca aaaagggcag agaagagaag ccaatcggta gcgtagaatc ttcaactgat
53881 agctctaaca tttctgttgc tacgagcggt aacaataaag aaagcaataa aaaaaaaaat
53941 aagaaaacgg ccatgctaaa tttcagcagt ttgacggacc ctataacgaa ctacaaacca
54001 atggatctgc aatacaagac atatgcatac tccatgaatg aactttatca tttgaaacca
54061 tctttggcaa gtgcttcgta cgaagaagac ccacttattt cggaacttgt gaggagttta
54121 cccaaaagaa agttttggcg attgcgcatg ggacctccag atcaaaagca tgctaataac
54181 catcatttta atgggaacaa tggtggaggc agttggaagg ctggttacaa gaatgggaaa
54241 aacgatgaga gaagaatgag tagaaccaaa aacatgcagg gaggcaaacg aagatctcaa
54301 caagatgatg aagaaaaaaa gattgaccaa gaaatgctgg agatggacaa gaatcttcaa
54361 ttaggaggtg acgtcggcca ttcaattgca gattttgaag attggaaggc aaagatgaaa
54421 gaattagaat tgaaaaaact ttcaaaatct aaaggaatca gtaactctac cgcaattgct
54481 cccagggaaa gcgcctctca tgaaacaccc accgatttaa gaccggtcat tccaaggggc
54541 cctagttcaa taacagattt tttgaattta aagaggcaag ataagaagga agaatcttca
54601 caacaaacac ctggtattcc tgttggacag ccaagcctat ccaaaaccag tatagaacaa
54661 gttaacgaat tagaaactaa ttcagatttg ggtaaaagtt catcatctcg gttttcatca
54721 tttttcaata aatctgccac ttcgttgcct tcattagata ataataatca agtgccatcg
54781 tcaaacgtgt ctgtagtaaa caacgatggc aacagtacac ctcatcaaag tggttcaaga
54841 ctgatgtcgt ttttcaaaga atctagatcg agcactccaa atgcagaatc gcagttgtta
54901 tcagcctcag acaaagataa tggaaagatg cagactcttc cgcaattcca gcagcaaccg
54961 caacaaatgc aaccaatggc atttacccag catcctccta ataacaacgc atttttcaat
55021 gggctattga ataaaggtaa aagtgaaact agtactcctc ctcctccacc cccaggacta
55081 attgctcatc agggtccaca atttcctgtg atgggtgtac caccaaattt tccacaacgc
55141 atgatgccac cgccaccagg tctcgttcaa ttccagaaag attctaaaga tgtaaataag
55201 aaggaagaca ggcaattaag gcaaaataaa aatccaaacg gaacaagaaa tagcaaggga
55261 aaacaagagg aaacagcaac gccagatctg cctcaacagc aatacatgcc accaccccca
55321 cctccagggt tttttccaat gcatcctaac tttcctaacg gcccaatgcc accattacca
55381 caggggttcc caatcccacc aaatggtatg ttaccggtaa caggacaaca gccacagcca
55441 ccttatccaa atatgatgct acaaggaaat ttccccccta atttccagca aggttttggt
55501 agtaactccc ctatgccaat tccatctatt attaatgcca atggcaaaaa tgttacaaac
55561 cagttaccac caggattaaa ctctaaaaag aatataaaat gagatgcgta acgagcgagt
55621 acttgacagg aaacgacaaa aacacagtga acatactatc taaaagcatg ttcttttcct
55681 tttcattttt catctttatt atctagagtt tgtatataac atgtatccta tattatctta
55741 tcctatcatc atcacttaac ttgttataat tctcccatat acttatgttt tcgcctttga
55801 tatttactag tcgaaggaac ttttttcgca gttagtaacg tcacgctcgg aactaaacat
55861 taatgaatga gatgcatttt tatacaacac ttttacaggc tatatacaac taagtgattt
55921 tcaatacatt aaaactacca gaatggacac caaccgatat aatgttggca taggttttcc
55981 actgatgtgg cttgttggat tagtttatcc acttgttctg gaacgtccaa gtcattaaac
56041 cttcttatat cgttccccgt taatttgtca gtaatgcgct tcaataccaa catggccctt
56101 gcatttcgaa tggcattctt gtgctcgttt tccacccttt gaacttcttc ttcggtaata
56161 gccccattac tcaatagctc attggcattc atcacgggaa gttgaatgcc cgtttcttcc
56221 tcaattttct ttgttggtaa gtcaaaaccc caattgatca aaggatcgaa agcaaaagct
56281 tcaaggattg ccattaatga acccttgtta tctctaagta ccttcataac attctcacaa
56341 gtaatacgga agctaccttc aattccactc acttccattg catatgttaa cattctagtt
56401 aatctaaaag gtactttttc ggggaatttt tctcttaata tagcagcctc gaaacaatca
56461 ccaaaatcaa tatgaatgac tttcccagtg attctatcca acatcaaatt actagggtgg
56521 cggtcaccta accccaatat ataaccggtc atggacatca cggctagcga tcgagtgtaa
56581 gtagttctac gctccaacca cgtttccgat gacctactct tcagccataa caccttataa
56641 agatcttgtc cctccgtatt atttagggcg taagtgaaga cttctacttt ctgcaacaac
56701 gttaaattgt cataatcagg tgccatttgt aacatgaccc aatgctcaat gtttaaagga
56761 atttttttgg cttctctatg ctccctaatt aatacatgga acgtgtcact attcggtacc
56821 caacccagta acccagactt cggagataat gggattgctg gatattgctg gatatctaga
56881 tgccttctaa agcactcagc gtcattttgc aaaagcgtgt taactagtcc gaataattgc
56941 atgaccaagc tatcctgtct aatgtcttca tgtcctttca acacatactt ataatcttta
57001 ccatcactac ccttgataca aaactttctc ggtctttgtt tggatgagat tactgaaaat
57061 actggctcga atttagatat tttaacaatt ggttttccac cacttgcacg ggtcccgggg
57121 acagccaatt ccaaatcatg cgcagatagt agttttggcg acacatgttg tagttcaaga
57181 gtttgtaatt gtggcaactg tttaccaatt ttcctgaaaa cattatagta aatgtcccac
57241 gcttggttta aattactaac atctttagat tttttgtaat tcatcagcca ttcgtaagcg
57301 tcattcaagt ccctaccaaa agaattttgg aacgatattt ccctcaaagt ttccggtcct
57361 ctcttcagca tttcgtacag aggctctaaa gcagcaaaca ttttttcggt attatgttct
57421 ccaaaaaact gcctactggc gtcatccaga ccctcatacc attgctcatg ccaaagcacc
57481 gccatacgta tcaattcgtg gctgacaagt tcagcctggt cgaccaaaac tggactatgt
57541 attctcatct tttctatgat ggacaaagct gctttctgtc gtgagagaga ttcggattta
57601 atcgcaacca ttaaggggta cactaatgcc tgcggatgag ccttacctag atcagataat
57661 agggagagta atgacctact aacaatttga ttgggttgat gaattctaga aattaactgt
57721 ggcaacactt ctaaccatgt gcctatttgg attaggttga aaccctcgtg catagcttgg
57781 gttgcttctg gaataccacc aaaagtaaac cataaagtta ataaccttaa tgcatcttga
57841 agagagcttg attctgataa agaaatggaa tgaaaaaaac ccttaattgc tggaattacg
57901 tgcctgtgta ttaaattaga agagtaatga acttccttag catcaaatgt attgacgccg
57961 atcatgccat tatcaaactc attaatatca gttaccgagg aagcatcact tccttcctgt
58021 ttctttttag agacagatgt tagcatagaa atgacttcaa aattggccag tgcccagtta
58081 tgccacgctt tgtaccatgt gttgtcaaaa tgtgtagcga gcaaatagga gcctaggatc
58141 gaatctggat tgctcaatct ccatttaggc tgtaagcaaa ctctccattc tccttgcttc
58201 aagaaacaac gagctaaaag cttagtataa tcttcaacgt gacgagggac tcttttgctt
58261 tgttgaggaa cgctttgagc tatcatatta tttggatcca aacctaaatc atgagccatt
58321 ctagatgtga aattaattaa ttgcttcaaa gcctcatctt gcaaccccgt agcccacaag
58381 tacttcagtt gtgcataaac aactggaggg gatgccttag cagtattagg atgatctggg
58441 tcatctgttt cttcaagcaa tgtatttaag acttttttag ctagcgccat cctacccgat
58501 tttctgcata agttggcaaa cttaatcctc acttgagcat cctcctttgg ctttatcacc
58561 aatgatctga cacgcagaat tctttgccac acatcaatat ttttttgaca gcccagtaat
58621 ctggtattcc aagtttctct catagttaga cgtttatctg aattttgtgg caacttctta
58681 tatttgatga tttcctccaa ctctgctata atctgcgctc taacaacaac attatatgct
58741 ctattgtagc tttcattaac aagagctgac aattcagtaa ctagaagatc ccttgcatta
58801 aagatgtgaa cttccgcctt cttaaaatta ttcctatgca aacataaaat tgcatcatag
58861 aattctttat ctggagactg cgatttcatg acgctagtat actgggctat ttcatcccat
58921 tgctccaaac cccaggcagc gccggcagcc aaaggcgcca ttgccttctt cacttcgggt
58981 tttgccgtgc cccacttttc agatgccaat ttagaaagct cttcccactc tccaagggca
59041 tataacgatc ttaattttcc catcatcact tcaaccgaat cttctcctgc tgcctccttc
59101 tcattatatg ctgcaagagc atcctcccaa cgttgaagtt tttcatacca agtttccttc
59161 agctgcaatt cattgtgttg ttgcgcatgc ttcaaaatac caatagcaga atcagtttgg
59221 tgaagttgat tattaatgct aatcaatgcc tcgattgttg aatttttcgg ctcttctaag
59281 aattctacct ctttgtaatg tagtgccttc gcaaaagcat gacatttttg ggcatactta
59341 cctaatgtat ggattgggat aggcaatggt ttgtcatcgt gctccataaa ttccactaaa
59401 tttaacaaca tttgataaat ctcgggtggg ttttcagagg atgataaagc cttgcataat
59461 gcttgaatca aatcctcttg gtatgacgtt tgaagctcaa cccagcaact tgagaatgaa
59521 gcattaaaca attctctcgc caacggataa taaacgctga ctaaactcga acaggatcgt
59581 agacaagctg aaggtgattc ctttagaagc tgaatagata gccttcttat ccattcttgc
59641 caatcttctt tggtcttctg ttgagaacaa taccatgcat tctttaggat attttggttt
59701 accggtaatt tcgttacttg catttcgtct tcataatttt tcctttcagg tacttcgttc
59761 tccttgtcaa atatgatatt tgttggcaag cattcattgt tcagtaattt attaaccagt
59821 tgatcgtaca ctgaatgctg aatcctattc ctcaataacg ccttgttaat cactggcaca
59881 aagaccacaa agtcggtacc tagttgtaaa aggagcaaac ttagcgtatt catggttgct
59941 tttgttagtt ctctatcccc attattcaaa attcttacca acgcctgaac aattcttgat
60001 gacatttcag agaggttgat attctttgct aatctaccca aagttataat ggagattttc
60061 tttagacttc cagcagaata ctcagtcatt ctaacaacga taggcataat caaatgggaa
60121 tagtcttcta gattcggccc aaaagtaacc aaagatttta atatacgaat cggaacgatc
60181 cttttattag actggtcgtt ctcaagaata tcaaggaaaa aggttagagt ctcgggaaca
60241 aatcttttaa actcaccttc cagagcctta gatatcgatt ctatgacaga aataattgtg
60301 atttgtagtt taatgatcgg gaaaaactcc ctgatcacac cataaatttt ctcgacatgg
60361 ggcctaatat gttgcttgac aattgagatg agagatccca gttgctgaaa ataaaagtca
60421 agttgggacg gcgggcatga acgcatgact aaaatgatac ctggaataat ttgatccaaa
60481 aaggagacac atcgtaaacc aaggttttga aaaatatgca taatagcttg aatagcagcc
60541 gtgtgatgga ttgacaacga tggatcattc aatatcttca tcagattgtg gataactaca
60601 gtggggtaat attcatcgtt ggatggagat accccttgca ttagcaatgc gatgtcgatt
60661 gaaggagcat tttgctctac tgaactcttt gagtttgatg tgacttctat ttctctgtgc
60721 ttatatggat caagagcgcc taatatacca atcaaacgaa cagttccacg cctgatatga
60781 gggttgtttt cagtcttaag aatatttatc aaaatgccaa gtaactctgg gtagtctagt
60841 aaagggccaa caacataacc agaggaagca gccagctgtc ctaatgttgt taaggcggca
60901 tctcttttaa aagagtttga ttggtcctga aatgtgttaa tgatcaatgg catcaattcc
60961 tttaagtaac gcgtcatttc ttttcctcca acaacagata gttcacccaa aacctttaaa
61021 gcggtggatg ctacggcaga tgaagcatcc tggcatttag gaagaatgac gtctagaata
61081 ggatcaatat aaggtttcgc tacttcatcg ctggaattta tcagcgtaca taatagagtt
61141 gcactttcct cctttttttt tggcatattt gagaacttca attgcgttaa tagttccagt
61201 aaagttttcc tcaaagaagg aactacataa gcggggttga cagaactcaa tctgcctatt
61261 attttgatag cttccaattg aataccaaaa atctcatcgt tcagcgccat gaaaagtagg
61321 cgtaaattgt ctggttgggc caattgagga tcaaaatttg accccaaatg ctgaagaatt
61381 tccaatctaa tttctgcaac cggatcagtt attgcgatca ttaatagctt acttagcact
61441 tcagaaaccg agtgtaaagc atgaactgat gtttgtttac atatatcgtc tttgataaat
61501 aaatcacacg acgttaatgc tgccaatttt ctgacagacg aatcctcatg ctcaatgtaa
61561 gaaatggtta taagcctaac aaactccgtc aaggaatatt gatgatgaat tagttgcagc
61621 attttaaaac actgaatcaa aatttgggca tctgtaatat cgtcattaga ttcaccagtt
61681 tttttcatga aactttggtt tcttgattta cgagcctttt caatggaaaa ttgattatta
61741 aaatcgtatt ggtttgattg aataaatttt tcaccagata aggatatcga cagtaaattt
61801 agtatcctcg aattaacggt agattccaaa gagggtattt tctcgttaag gatcattaaa
61861 gtctcctgca tatggtcgga cattggacag tttaacatca aattaagaag atctttgttc
61921 aagtgcttag caaaagctgg gcccaaagca caagctaatt taccaatgca ataaaataaa
61981 tccttctcga attgttttct aactttgaat ttcgttctta agccttccct aatattatcc
62041 agaataagtg tcatataggg tgaaatgctc gaaccaactt caaatgcaat atcacctata
62101 gaaactaata taaaaggttt atccgaatta tttgcagcat tcatatcgat gttcttcaaa
62161 tatcttaaat aatgaaccat tatcctatcg agatatttct ttgtgaaaat ggcagggtca
62221 aaagcagcta aaagaggtaa aatagcataa acttctctcc ttataacatc aaatttatat
62281 tccttgtact tcatagtaga tttgtaaata tcatcatatt tatccctgag ataaggtgct
62341 ttcaagctga gtaattctcg aaataccaac agagtagcat gcactgaatc attcgtattg
62401 agacttaagc catgtgtaca accttgaaat aatctttgaa accactgttt tcccaaagca
62461 gggtctctat cctgaataat agtaagacat ttacccaatg ccactgcggc atctaatcgt
62521 ataattaact ttgcatccct taatggcacc caaatattgt ctaagataga gttaacgtaa
62581 gggtataaaa gatagggtga attgtctgct aatgccttta tgattaatag cgcagcatgt
62641 ctcctgtatt ccaacttaga gctcgatgag ttattatctg ctgtcagagt aagccaatca
62701 atgcaagttc tgacctcaaa ttcgacgaaa tctgatgtta atgtaccacc tggcacggtc
62761 aatctaccta aggtgttagc cgctaatctc ataacttcaa tgtcactgga tggaattaaa
62821 acacgtaaat agttcgccag tcttgaagtt tggtttggca gctcctctgt actcaggtag
62881 aatgagatca gagtatcaac agcaagaata ccacctatct tctcacttga agtaaacccg
62941 tgaataagtt caaatatctt attgtttaaa ctgttgctaa acctttgaaa ttgctcagca
63001 gatacttccc ttgctaatga ggtcaaagta gtgcttaatt cattagcgcc agaggctcgt
63061 tcttgtggca catcgctttt aagtttatca aaaatcaaat ttaaagtaga aaatgttgta
63121 tctagttctg aatctacaaa ggatatttta ccaatatgac cagcagaacc agtgatcact
63181 ctaccagagt cattgggccc attgtgattg gaatctgtgt ttgaagtagt tgacatctca
63241 tcatcgtggg agtgcgattt gtgtgtaagt ttctttcttg ttctgtgttt gccttcggcc
63301 ctttgtcgta aagacaataa gttaggtggc gtggtgtatt tgttaatgta tttattcatt
63361 tttcatatgg ggaaagtaaa gatcagaaat ctctttgaga aagataacta tttgatctta
63421 atgactatgc tctttatgca cccggtatat tttccctttc tactgctcct aatctacctg
63481 taaataaata caagtaaagc tcagttaagg aagtgattgg tgtcacgatg ataaaaattg
63541 gtctttccta ctgtcattac atttcttcca attttaattg ctgccatata tgtcagtctc
63601 tattcaaaca tattcagtgc ttaaaaagga atatccgggt aaatattctg acatcgccca
63661 agaaatatac gatataactt aaagaaaaga gttgtagtaa gctaatagca ttaagattaa
63721 atgtatgttt gattaattgc aatatcatga tgttatagag taacgtggta taattaccac
63781 gattccgtcg aattgtttgc cacttatcac tggcgccaaa atgcagcagt atgtaaaaaa
63841 tgacggtaat aaatatataa tacaaatgca tagaggaaag gctatagaaa tgaagagatt
63901 catgaatttt cagtcaggtt ctccgacttt taattgctgt gcccctcctc ctgcttcttt
63961 ttttcctctt cttcgttctt cttcttttct tcctcttcct gcttcttctt ttcttcatct
64021 tcattcttct tgtttttctc ttcctgcttc tttttttcct cttcttcgtt cttcttcttt
64081 tcttcatctt cattcttctt attttcttca tcttcattct tcatcttttc tccttcttcc
64141 tgcttcttct tctcttcttc ttccttcttc tttttctcct cttcctcctg cttcttcttt
64201 tcttcttctt ccttcttttt cttctcttct tcttccttct ttttcttctc ttcctcttcc
64261 ttctttttct tttcttcttc ttccttcttc ttcttttcct cttcttcctt cttcttcttc
64321 tcctcttcct ccttcttctt cttctccctc cgctttcttt cttcaagtaa cttggcataa
64381 gcatagtcct cgtatacaat aatagggtcc ttatcaaaca tttgaatacc ctttctgtta
64441 acgtcggata aagttggcgc aaaaaggtct aaaccatatg aatttaaatc caaaaaggag
64501 ttgctactaa agtttaaatt tgatttaaaa tccacaggat ttacttcaac agtattagca
64561 ggagtataat cttctgtgtt atcatctaga gttgttccag tttcatcaaa agtaatgttg
64621 aaaagtgaaa aattcctgta tttcaaactt tcggacagat caataatttt tccgacatat
64681 tcttcatgaa caatcttggt aacttgatct aatgtagtct ggttcataga ttttgataaa
64741 tccttccaca tagctttttc ataaccaaaa agaaatgggt cctttgcagg ggagcttaac
64801 ttaggagcaa cattaatgcg caattgatgt aataatttct ttttttcaat aaatgtcagg
64861 ttttggcagt attgaatttc caattccttt tgcctatatg cagtgacatt gaaggaattg
64921 tacaagttag taaatacctc gataaagcca gcttttggaa tatttttata aattaagcga
64981 acatcatcca tggataggtt tttgaaagag tattcagaga ctttgttgga atcaaaaagt
65041 ttcgactcaa atttcgtaga cgatatttct ttcaagaggt tcggattcca tgaattaata
65101 ctggggatgt ttggatacca tgaattaata ttactgcatt tctttaaccc gtcatagtcg
65161 aaccaaaatc taaattcggg caaataagca gtatttttgt aagcatcaaa tgcatatcta
65221 tcaggtacat gatattcatt gtgcaagcag taggtatgtc tgtgaggaat caacgctggc
65281 acaccatgga aaacagtatt gattaaggga gatagttcct cgaacgagtt aaaatggttg
65341 tttctacaat tgtaaagttt aagtttttcg ttgagaaaat atctttgttt aggattcaac
65401 ttgttttcaa tggtcttaga ctttggtaac tcttccagtt cctttttcaa aagatctttc
65461 aaatcagtat cagtggggac tcttttatga tttttatttt cgtcgctggt aatgtaatca
65521 cgtagctcag tgatgtttag tgtagccata ttgactaacc catcatctac tttgtcgggc
65581 aaagtagcgg tctcaccgtt cgattcaggg atattattga tatccaaatg ttcctcttgc
65641 aaccgctctt caatataaga attcaagtaa tccctactag gggcagaagt gctagctaga
65701 ccggtaatat caatgtaaag gccggtgtcg acgtcaatga atcttgcatc gatattgttt
65761 ttaccgttac cgttaattct tactgtcaag gagtcgctga cgtctaggaa ataacgtcca
65821 ttaccctgtc ttgggtcttc caatataaga gattggttga agtattgact gagcaattgt
65881 aaatgcttaa tgggcatttg caagtcgaaa tcgttatccc aagggaaagc cattccattg
65941 taaagatagc cgtacagcgt tccgtgagac aaccaagata tgatgccgtt ggctttagta
66001 aacttttgga atgttctgat cattgagttc aatctagcct ggtattcttg tttatcattg
66061 attaatgtat caacattgaa gaacctcttg tcacgatgga accccatacc tttatattgc
66121 ttcacggcac cagcctcata gaagaacttt ctttgcaatg cagggcttgt ctttacggaa
66181 ttcttcaaac tgttcagata attctcatta tgagcggaaa atttgtccgg atagagtttc
66241 ttctgttcct ctaactcttc aatttttttg gaggcatcga acttgaaatc cgaaggggat
66301 aaataaacca aatctttatc aaaagtgaat ttatcagttt cttcaatttc cagtttgtat
66361 agggagttaa cttggtcgtt attgacgaat tcctggaaaa gcctgttatg gttgaattct
66421 acgtcctgtt tatttttctt tctcttgttc gtagaattaa tgttatcatt aatatattcc
66481 tgcaacaggc cggattgcac caagtttttt gatttttcag tttgcaaggg gacttgatac
66541 gtggaattat ctgattcgat gatggaaatg gatagtggat gcgactgtgt agtcaaaatg
66601 tagtttcttg cctgcaattg gtaaacttcg ggtctaactt tatcatacag ctcctttatt
66661 tgaaattgcg tattaaatct taaaccctta ggagagccat gcccgtctgg agtgaatagc
66721 ttggaacaat gcttttttag ttcctttgag tctttgattc tgtcctggtt tctagcggcc
66781 ttgtaccaca gtttctgcgc gtactttggt ctttcgtata ggaacaaagg ttcgccgagc
66841 tctgtctcaa tggcctctaa agactctttg tcgaaagcgg actggaaaag aaaattgcag
66901 ggcagaacag ttttatctat ggaaatcagc ttattcagct cgtggaaggt tgtccagtcg
66961 taccatgaaa agggtaactt ttctggctga tctgcgtcat tattttgcaa atggttcagc
67021 acaacggacc acgtgagacg agggtcgaag tcgtaaaact tcaactcatc cacggattcg
67081 agcttactgc cctttcgagg gcccattttg accgagagca ggtcattttg cagagtatat
67141 tcattgaccc atttagggtt ggtgccgaat tttaaatttt cgtataatgt cttagcgaac
67201 tggatcttgc gatcgttttt gaaagacgaa gtcaggatgc tataccagga atcatcatca
67261 ctgtcaagtt cgttgtaatt tggtagaagg taatcagcgt cccgcccaag tccgttacgc
67321 tgcggtgaat ttgaccagat aaacgttata atgatgatct gcagtagaat cagtggaagg
67381 agaatgcgcc ttaatgggta gtgcttgaca cgcagcaggc cagataagaa ccgcctgtga
67441 agtttagatg atattcgctg aagcataact aattagttta tttgtgtgaa ggaatagtga
67501 cgttgtgatg cggtgagttc ggcggttagg ggaatggtat atgataaaaa acggaaacgt
67561 gcttctttaa tttaattgtt taatattgtt gcagatatat aaaaaggggg aaagaaccaa
67621 agatgtaatt atttctttat tgcctcaacc taaagcaagc aataaggtat agagatcagg
67681 acgtctcgag agctgatatc aaatttgaag ccacgcaagt aactacgtag gtcagagggc
67741 acaaggaata acacgtgaca tttttctttt ttcttttttt tttttttttt tttttttgtt
67801 agtcttggct tctgtgccgt agtctgtata cggttttaga tgcggtatgt ttatcatcgc
67861 ccagaaattt gcggggtgca aagaaataaa atccgtgctg aaacccgtgc tgaaatccgt
67921 gcaccgcatc aaattttctc ggaggattct ttgcgccggt tttcattttc ttccacggaa
67981 taccaagccc attgcatcgc gatgttagtt tagcggagtt tcttggcatt ggcaaatctc
68041 tgctaaatgc tgcgtacaga cggaaactca caccgccgcg aagactggtc agtggcaaaa
68101 aaaaaataaa aatatagaaa ataactatta cgtatgttac tgtttctggt agttgatatg
68161 aagttggagt tgtatattgt acgctttagg aacagggaag tgaatattat ttactctgct
68221 gcacattctg gctaggtcga agccggaact tgagaagacg ccgcgctaga actatggacc
68281 aagctgttga caatgttcag atggtgatgc actaccctgt gcggggagtg gccacggacg
68341 cgagcggaag gtgcggaagg tgcggaaggt gcgggagttg cgggaggttc ttcgctaagc
68401 gtgagggttg ctagctgggg cggcggggtt tccctaagtg taaataaggc ctcggctggc
68461 acatgagtcg ccggaggagg cggcggaggc gacgacgcta aaaccgtggc cgttggggaa
68521 ggatgggcgg ctatatctac cattgacctg atggggactc ggttcttaag gaatgggttt
68581 gaggtgggtg tggttgcagc aacatctgta gcgatatgga aaccccgcgg attctcgtac
68641 gtagtggttt tgataatagg tttcttacac acatatttgt cgttggcatc aacacaagtc
68701 tcaattcctt ggaaccatgg gtcttcgaag aggtcgtcga tggtgtagcg ggtggcggct
68761 tctgggtcag cgagccgcca tgccacgcga gatgcatgtc cgttcttgaa atttctagcc
68821 aagtgatact ccattcccgg ccccgggcgg taattgccgc gattgcggaa tgcgcgatcg
68881 tgaagacgga taaagttttc ataagcgtca cagtaatcgc ggaaaccagt gtcgaagctg
68941 caggattcca aaaatggaat gacgttgttg acgagggtca tgaggataat acccaggcca
69001 taacagtcta gagcgcgtgg gtcatacggc tgttgcaatt ccgtatcgta gtgcttcttg
69061 gagtcgtaga acatgacctc cgggggagca tacggcggcg agccgatcat ccctgcgcac
69121 ttcttgacag ggctggacag gtcgtgtgga tccgtgtggt accagtctga gataccaaaa
69181 tctgtcagct tgcacacgcc gtccggggat agcagtacat tttccggttt caaatcacgg
69241 tgggcgatgc cctgatcgtg gcaaaacttg acaccacacg ccacctgttt gaatatacaa
69301 aacttttctg ctagggccac gctgcgccag cccgattttt gtatcatcgc gaacaaatct
69361 cgtagaccta gctccatgac gaacccccac ccgcgagtgg tgtagacggt ggtgggcacc
69421 ttgactagaa ggaaagtatt tgtgatgtga acatgatgac ttagctgctt tgcgatgata
69481 aactcctttg agcagcgctt gtagaatttc tcgggcgttt cattatagat catattgagc
69541 ttctttagag caaatacgtc cttcttgcgg tacttggagc ggatcttgcg cacttcgcac
69601 gaaccgcccc atccgatggt cttattctca tcatcaaaga cgaagttatc gctcaactgg
69661 atgcttgcct ccttcatctc gtcgggcaga tactcgtttg ggtccacaat tgggatcggc
69721 agcatgcgga ttttggaatc cccatcgtga aggtagaagc ccagatcagg gtctttcttc
69781 atggaggtag agacggacga gagtgacgtg cttggggttg agacgccgta tggattgtac
69841 actaatcgtt cgctactgaa cttggagttt gagagattac gcgaagtgga cgaatgtctg
69901 tttcctcttg agatggacgt gctggagccg gccggaggta ggatcttggt tgaggcggaa
69961 gataaagatc tcttgctgtt ggttgtgtga gcgaaagagt ttgcacggcg agaggttttc
70021 aacgaattcg gcagttttgg gctggaggat tcgctgtcat tagtacttgt agagtggaag
70081 tctggaggta gagacgcctt tttcttcaac ttgttcccat ggcttgaact taacagcttc
70141 tttccgaaga acttaaatgc tgataccgag gagattggtt gttgggatat cttcgtagaa
70201 tgattgtgtg agactgtcat tggttggtgg tgcgatttaa tgcgtatgct tgcctgtggc
70261 gttaaaatgg tctatacgtt tatgctaata tttcttgatg taatgcaggg cctatgaata
70321 catggaggtt tgttgccggt ggtatacggt tgaaaaaaaa aagaaataga tatatatata
70381 tttcttcttt gtatagactt ctgcgagaaa aagaaaagat aaggaaaaat gaaaaaaaaa
70441 gcgtataggt gctaagaaga attaagtatc aaaaggtagc aggcatttat gttatatatg
70501 caacttcgga tttcgttcaa tacatcttga ccggtctcca ctgttactgg catatttctc
70561 gggtttttcc ttttcaccac aagggaaaaa aaatgcgtta tgtaatttca ccaatatttt
70621 tcccgtcctg cgtgctcgca caatacaata gggtcatgtc acgtaataag caacgtgcgc
70681 cgcatttttt gccctttaaa gggaaacgcg ctttgttctt ttcttcttcc ttttcacata
70741 agggagagtc ggctaccaat gtcgatggaa ttctcaccat tgggcatctc accgttccta
70801 tccttctgga acctatcgta aatccccctt aatttgacca actcacttgt tgaaatacta
70861 ggttttgtct cttgacaggc ttccaataaa tcgtttattg tgaccacagc tgtcagctca
70921 gaagcagctg aagtgcttgt ctttgtctcg tgcaccacat cttgctgcaa tagagtcttt
70981 agccgtagtc tattttcttc tctacgcccg tgctcattga tactgaagta ttctatatta
71041 tcattgccgg gtaccacttc cgattggtct gcagcagaca gccacctatg tacagatttc
71101 aaataagcat tgtagcagag cccctgtaaa tcagcacccg aaaaaccagc tgtcttttca
71161 gcgatcaact tcaagtctgc atttttctcc aatgcaaatt ttttttgtcc cgtatccttg
71221 tcttttgaat tgacgatagc ttgcaagata tctaacctct ctgattcagt cggtatatta
71281 cagatcacac ttttgtctaa tcttcccggt cttaacaatg cgctatcaat caaatcaggt
71341 ctacttgtag ctgctagtat atatacacca tcaaggccct cggcaccatc catttgggtc
71401 aataattgat tgactacacg gtctgtgaca ccagtggagt catgccctct ctttggcgca
71461 atagaatcga actcgtcaaa aaatagaata cagggtttga cggactgtgc cctttcaaac
71521 aattctctta tgttttgttc gctggcacct ataaacttgt ttaaaatctc tggtccctta
71581 acggagataa agtttaaccc acattgttgt gccacggcgc tcgccagaag cgttttacca
71641 caaccaggat aaccgtaaag caagattcct gatctcaatc ttaggggaca attaacgaaa
71701 ataggctcat attttgtggg ccactctaag gtttctagaa ggacatcttt ggcatttgct
71761 aaagcaccaa tatcccccca tttgatgttc gtttcttttg ttagctttac tccacgcaac
71821 gcagatggtg taaacgcact aagcgacttc gaaaaaagtt cccttgttac aacattatca
71881 caatctcttt ccaactgcaa gtcgtagaaa atcttttctg tgaatatttc caaatctagt
71941 ggcgaaaatc cttctgtctc caacgacaaa tcactgaatt gcaaatctcg atttagtttc
72001 atgatctggt ttttcgagaa aaaatactcc agtaacttcg ctcttgcatg tttgtcaggt
72061 gctctcaaag accacgtctc tgaaacaaaa tgcttatcaa acaatagcgg attaatttga
72121 gttttctgct tgcctgaaaa taaaactctg attcgtttat tatccttgtt aaatatcttt
72181 gtcacctgat tgatgaaaaa attcaaaagt ttgcttgcat tatcccattg gccattatta
72241 gaaggatctc cgtcattggc ttgaggtttt ccaaatagag cctcaacgtt atccaacaca
72301 atcaaagaag gaccatacca ataacaaaaa gaacaccatt ccataattaa tttttgggtt
72361 ttatctaaat ttgatgtctc gtgcaatgtt tcacaatccg catatttaac gaagatgtga
72421 tgatcttttt ccacttcatt tataagctct tttaataacc ttgttttacc gatcccttgc
72481 ttaccatcta atataatagc tggtgtggca ataataggcg atgtcaaata attgaccatt
72541 tctttcttga tactatttac cgtaatgaaa tcatcttcat ctttactagt gcgcgaaact
72601 tcgccagttt ctttgacgtg gtaatgttta ggcaaatgcc tttcgataat atctttaact
72661 tcttctttac ccatttgggt tactttccat tgaacggatt cattggaaat ttcattcaaa
72721 ttacacaact gctgctcgga ttcacctttt tttatttcga ttataatttg ctctgttgga
72781 agtattaagt tattggtcaa taagctcccg cccaacaact tagaatactg atccccactc
72841 ttggtaggaa cgtccttgcc aaaatatttg atattgactg ttgcatttct tccggatatt
72901 atatttgctt gattcatttg tagaaactct agtttgattt ttgctccgtt cattgggtgc
72961 gtaaagaatg catcccaaag atgagagctt aatgcaatgt gattttcggg tatctgacta
73021 tcacatttta taaaaacccc aatcttcttc gaagggatac caactgattt attatctgaa
73081 tcgcttttct tggactgcct taagctacat tttacgatag aagcgtagcc cttctgagaa
73141 ggcaattgtg ccccgtcact gatatatacg acaaaaaggt tatctttagg gaagtccatt
73201 ttgcacacag tactcctcaa tattaccttc tttaaaagtt ggatagcccc attttttagt
73261 attgtcttat tactatgacc atactcagcc ttcaccaaac gtgttttatt gacttttggt
73321 gccacaacaa ccaaggaacc atctgtgatc ctcgcagact tcattgatgg ctccaccctg
73381 tcaattttga actttgtaac aattccttcc aaataacaaa tcaaagtctc acctggggta
73441 actatacggg tttggtgcaa aatctcacca ttttggaacc tcatcgcatt ggcatcgata
73501 atttcccaat catcactcgt ttctggcgtg acatacacct ccgtagccag gtgtgtgtgg
73561 tcatatcgct ggatgtataa gtccaccaat ggagactttt gatttaaatc atatactgtg
73621 gccaaaacag gattgataag aacaacattc tcactcgatc cagaatcatg gccatcccat
73681 ccaagatgaa caataggtat atctgaatta tgagaatgga ctgctatacc gaattcctgg
73741 atagcgtagt tggttgactc taacacgttt ataattgaat gcggtaacct taaaaagttt
73801 cctactatgg cattggagaa ttggattctc agattctcaa acttcaacct cttggtcgtc
73861 gtcatttgaa agagcagttc ctcaggtgtt tcttgttact gccgtccctt ccagaagaaa
73921 ttcgacgatg acaatagtcg gagagatatt ccggaccttt ataattgcgg ctacgcacaa
73981 gaataaatcg cgatagtaat cggatataag acaataaagt ccagctaact tggttggaga
74041 attcgacaga ttaccatgaa tatagaaatc gatgtttttt tttgtccacg ccgattgatc
74101 agccattttt ttttatcagg gtcgcaactg ccctgtgcaa ataagaaagc ctgaaatggt
74161 tgcacaaaga ccacaaacaa gggcatacgc cagtacagta ttatggactc atgccatcga
74221 ggttacatag aattagttta aacaaaaacc aactatcctc taatatccat ggtacgagta
74281 tatataattg tatgaagtgt aagaatatga tataaataat gagagcactc atagagagta
74341 acggcgctga attgtaagaa ctgtcacgta gtaacacaat cactgaaagc atataaagtg
74401 aaatgagaaa cggtagtaat atcatatgca ttaccaattc cttttagtga atttccatgt
74461 gcccgagggg ggacttccag tatattctgt tacatttaag taaatacttc atcaacaaat
74521 agggcccagc ggtttcttac actaattata catttacaac gtaaatgctc cagctcaagc
74581 attatttata tatcttgttt tcaaaagaaa aatatagcaa ttagactcca tggccaagtt
74641 ggttaaggcg tgcgactgtt aatcgcaaga tcgtgagttc aaccctcact ggggtcgctt
74701 atttttaact tttttacact gaagaaacaa atcaattcta atacaatgcc aatggcttca
74761 aatcaacctt tggttataat agttaggaga atcgatgctt acatagtata ttatttaaac
74821 aattaatttg atttaaaaga tttttgtttc ccttgctgct gtcattggct ttctaaatta
74881 cataaagcag atgaaaagcc acactatgct gaaaatagtg tgtggatgca tctacatgat
74941 gatgcaacac gaattggatt ttttagcttg cttataaaac attttggaac ttgccgttaa
75001 tgactccgat ttgtccacca aattatccaa cttttcacct ctttgtaaaa cattctcaat
75061 cgttttgtgc aaaacgattt tcgtctcatc cagttcttgt tgaactttca tgatagcgtc
75121 agcctgtgaa ggatcttgat atttgctaat gtaagtgtcc agttgcttca ttttcaatgc
75181 atcattggtc tcagtcacat ctgcccactc ttccttagga tgtgcgacta aatattcatc
75241 caatattttg tttaatagtg tgtatgctgg tctgacagga tattctttgt cggtgatcaa
75301 aacaccacat atgccctcac tcctggcata aacgtggcca atatagttgc cttcttctat
75361 actttgtctt tgtcctgcac cagttctaga agcgaccgtt tcagcaaaaa aagtcataaa
75421 ctggccaaca ctagaccttt caaagaaacc aaattgtgac aagtctttaa cttcactcaa
75481 ctctagagcc ttttctcctc cagagcgaaa tacaccgatg tagtagattc tcattgccaa
75541 aataacttct ctagtgatac gtaaagcttc agaaatgccc tagcctggtc taacgcagtc
75601 aaactgtgcc agagactttt gtatattgtt catgttgata tctattgtgc ttgctcttga
75661 tttcacacca agccaatcgt tctgtacggc acgccaccca ataagaaaaa aagggaaaag
75721 gagccgaatt ttggtttaaa aacatataat gctgaaattg tggaacacca attaccaact
75781 ggaagtaggc tcgatccaaa gagtgtatat tatcagtaaa atgcttcgca acttagtcgt
75841 caggaatgcg tgcagaaaca ggccgtcaat tcaagtggca agggggttat gccgacacca
75901 aacaagacgt ctcatggcgt cctcccctca gttcggtagg aactccaatc aggaaaaaac
75961 agcgggcttt ataatgggga ttctttctat ggctggtgct ttatatttta ttgctcctaa
76021 taggaagcct cttttcgcct caaggaaggt agaatccgat aaaaccgcag aggaagagct
76081 ttccagtggt ggtgagcaat caccagaaaa tgaagatgac aacaacagca aaagcgatga
76141 aaatggagat gacaacgaca gcaaaaacga tgaaactgaa gctggccctc aattaggggg
76201 tgataaaatt ggtgcttcaa aagtagctga agatggtgaa ttggttgttc tagcagaaga
76261 agacaacaag tcttccgaag ataaagatac tgatgaatca aaggtatcaa ccaaagatga
76321 tgagcaatcc aatgaagaca atgccaccgc taacaatcaa aaggatgaaa acataagttc
76381 tgagaactcg gaagaaaata ctagtgacaa aacactagac aacaatgctg gatcttctga
76441 aaaaaaagat ccagaacatt cagatgatga aaaatcgcaa cagggacaat ctgatgacaa
76501 gacaactact gaagataata atggagaaga agaatcctca aaaaaaactg taagtgactc
76561 ggaaaattca gctaagcaat ctgaatctag cgatgaagag aaagaagaac taagaaaaca
76621 agaggaaaag caaatgggtc ctactgaaga agaggttcaa cacgaaggtg cttataaccc
76681 agacactggt gagataaatt gggactgtcc ttgcttggga ggtatggccc atggaccctg
76741 tggtgaagag ttcaaatctg cattttcttg cttcgtctat tctgaagctg aaccaaaagg
76801 tatcgactgt gttgaaaagt ttcaacatat gcaagactgt ttcagaaaat accccgagca
76861 ttatgcagaa caactaaagg aaacatctga tgatgaggaa cctcaagaca aagtaaaggt
76921 caacacaata gaatcagcgc caaatgtttc aagcgcaaag gaaaatgctg cgaaaaaagc
76981 agagcaatca gatgtgaaaa aagaaccatt gaatgaggaa tccaaacctt aaaatctcct
77041 gaaaatctcc cgaacgtaaa aagtataaaa gtataaagga tgatacatgt aaatacagta
77101 atattatctt agtttaatga ctacatatgg tataatatgt gaaatataca tgaattaatg
77161 catctgtggg gcggatgagt ctagtctctg tatgaatcca gctatacatc aaatcgtatc
77221 cttttattta cagggcaagt ttgtcatata ttttaagtta cttgtagttt ttttccagct
77281 caataaattt ttcccaaatt tgagacattg taagtttctc gaaactcttt ctattatcac
77341 gttctcgaat gttgtatttc tgtaactgta cttcctcatc acccacgata attaaatagg
77401 aatagttttt caaaatggcc gacttgatcc tataccctac gggttcgttt cttatgtcga
77461 gatcaacatt gaaatgccaa tcatttaaag gaactggttc catgtcgtcg gcttccagtt
77521 cattacgtag ttttttctgc aaggcagtgc acatgtctag ctgttgcaca tttttcgtat
77581 tgacgggaat aattacagct tggtaaggat tcaaccaaaa cggccaacgg ccctcattag
77641 aatctatcag taaagccata aatctttcga tagaaccaaa agtagctcta tgaatcataa
77701 ttggcctctt gtacgagttg tcttgatcct tgaatttcaa atcgaacctc tcaggtagct
77761 gaaagtccaa ctgaatagta gcgacttgat gagttttgcg taaatggtcc gtaaccatta
77821 tatccaactt tggaccatag aacgcaccat caccagggtt cagtttccac ggtttgcctg
77881 attcttccaa gatttccttg agtacttgct cagcatgatt ccaaactttg aggtctccaa
77941 tgaagtgatc cggtcttgta gaaaagttta taaaataatt gctctctgct ccagaacctc
78001 ctttaacaaa ggggaaaatt ttgttgtaaa ctatgtcgat taattttaaa gagttgaaaa
78061 tttctgattt cacttgggaa ggagtgcaaa agatatgacc atcgtcttga tggaacttcc
78121 ttagtctagt caatcccgac agtgcaccag aagcttcatt tctatgtagt ggtgaaaaat
78181 cagagaagcg taggggaagt tcgttatacg atctatcctt tttaccgaag atcagacaat
78241 ggcctgggca attcatcggt tttaaaccgt attcctcctt ttcttcatcc gtagtttcca
78301 ccttaaacat gtcatcagca taattttccc agtgaccaga cttttcccaa agagtctttt
78361 tgtaaatcaa aggcgtcaca acttcattaa aaccaaattt gaacttttgt tgtaacttca
78421 taaactctat caatttgttg aaaatcttag caccatttgg aagaaagaac atggatccag
78481 gagatagtgg atctgtcatg aaaagatctt gcctctgaga taccatggat gtcatagtag
78541 ctggagtcgc cgacgaagcg ttcttagtgg cctttctcgt agagtagaaa gcacgattcc
78601 aaagagcatt gcgagaacaa tgccatctta caagttgtat tttcatattg cgagacagaa
78661 ggacgtgccc ttagctattg catatgtttt tctttatgta gttcagcagc tcttcttttt
78721 ttcatgctcg aggtttttaa gggcgaactt taactagatg gattattcag ttttttttaa
78781 aaggatcaaa atcctacatt atatatatat atatatatat atgtttgtgt gtgtatataa
78841 aaaaaaaatc atttcttgat caagatcagc ctcttatata tgtcgcatca atcttctgta
78901 gggatggagg taagttcata gtcagttttc ttctatacga agtcttattt tccagttgaa
78961 tagggtttcc ctccagataa atggtctcca agcgtgatag ggcggacagg ttttcaccca
79021 agctctcaaa ggattgatct atcttgttaa aggaggccca tatgtcagtt aaatttgaca
79081 ggtggttcaa gttttccagg gaggtaattt tgttggaggt cacgtccaaa gtagttagtt
79141 ttaggttttt ctctagacct tcaatcttgg tgatgaaatt atgtgacaga tagagctctt
79201 caagattggt caactcttct agattttcaa ttttttttaa tttattagat tggatggaca
79261 atatcttcaa attctttaaa ggatgtaagt taataagtct tggtatggaa tttttaccca
79321 accaaatttc ttccaagttt gacagacctt cgaaggaatc gggttcaata gaatgaacct
79381 tattaccacc taattctaag tttttcagtg atttcaaagt ggacagattt tcaattttgg
79441 aaatgctgtt ctgcacgaag tataaattct ccagatcagt caaattttct agatttttga
79501 tgtgcttgat cttgttaaac gacaggtcta gagacgttaa tttggtgagc ttattaacat
79561 tagaggagat atgtttaatt ttgttatcgt aaaaatcaag gtcaacaatc ttgtcatggg
79621 gtaaaacttc cacttcgctt atgctttcga tcaggttctg tctgagacat aattgtttca
79681 aattcttgaa cctataaagg ttcaaatctt ctaacgattt gatttttaga tggaccaagt
79741 caataacctc tacatcatca ggcagatctt gtgtcagttc cgaatctgca gtgatgaagt
79801 caggatttgt atcgtctaca acctcaatct tgtgtctttc gtctttttct tcactatctt
79861 tgttaactga attcttatcc ataatgatgg ctatgtggtg ctagatttct tccgacttct
79921 tgctattttc attcaaaagg ttatacatgt tttatttttc aacagtacct taatatataa
79981 taattcgggg ccaaaataac aaacaacgag aaaaagggag gagagagtaa agtatagtat
80041 taacagggct ggttatatag atatatatat atacgggtca atcgatctat ttatatacat
80101 acgaatataa tatgacatgg gggtgacacg atacaatata atagagcggg gacggacact
80161 tagtttgcgt cgggattgga agcgatataa tcgaccgttt caccaacact tctcaactca
80221 tcagccactt tgtcagggat ttcaatatca aattcttctt caatagctac gagcagctcg
80281 acagtgtcca aggagtccaa ccccaaatcc ttgtgaaatt gggtatcgct ggagatttgc
80341 ttgttggcaa tgttgggaga gttcttatca aacgccttga taacatcaat gaccctttga
80401 gaaacctgat ctttgctcaa gtttgcagaa taaaatcttt gtgcgagtat ggtgttggac
80461 ataacggaac ggcccattat agtgcggtac gcagaaggtg ccacgcggga agaaatgcgg
80521 caaacggatc taaacatggc aaggaaggtg ctgtattgag ttagttgtgt tgtttgtact
80581 aattacactg caagtgtgac tattcttcct tttgcttcgt catcaccacc tttctctttt
80641 actcagaacc cgttcgaagg ggcgaagaaa gaagcaattg acaaataatc tgtattccgt
80701 caacagtgat atatgtcacg tgactctgat aaaactccat ggagtctctt cggagtgtat
80761 gtgtgaaaag aataatacat ataagacatc tacaggatca gtctgatagt tttaatgcta
80821 tggtagactt cagaatgtct ttttaagtat gccatttggt taaatctgtc cttttatatg
80881 tacttggtgc ttcttttttc tttacttttt tttttttcag tgagaagctc atcgcaacaa
80941 gaagaaaaaa gactagttca aaggtaaaag agttaagatg attagtgatg gatttctaag
81001 tggcagcgtt gaaagatcgt gcaaaggttg aaaaatggaa gttgcaccgg ccttatcgac
81061 tactcagtcg gacgtggcgt ttcagaaggt ggagacacat gaaattgaca ggtcttcata
81121 cttggggcca tgttataata gcgatgagct tatgcaactt atctcggctt attacaatgt
81181 cgagcctctc gtgggttatc tggaacagca cccggagtac caaaacgtga ccttgcagtt
81241 tcctgacgat ttaatcaagg actcctcgtt gatagtaagg ctgctgcaat cgaaatttcc
81301 ccatgggaag ataaagtttt gggttttagc tgacacagcg tacagtgcat gctgtgtaga
81361 cgaggtcgct gctgaacacg tacatgcaga agtcgtggta cattttggtg acgcatgttt
81421 gaacgccatc caaaacttgc ccgtggttta ctcattcgga actccatttt tggatttggc
81481 actggtggtg gagaactttc agagggcatt cccagactta tcctccaaaa tttgtttgat
81541 ggcaaacgca cccttctcta agcatttgtc acagctgtac aatattttga agggcgacct
81601 gcactacaca aatatcatat attcccaagt gaacacctct gcggtagaag aaaaattcgt
81661 aaccatactt gacacctttc acgttcccga agacgtagac caggtgggtg tgttcgaaaa
81721 aaatagcgtg ctgtttggtc agcacgacaa agcagacaac atctcgcccg aggactatca
81781 tcttttccat ttgaccaccc cacaggatcc gagattactg tatttgtcta ctgtgtttca
81841 atctgttcat attttcgatc cggctttacc tggcatggta acggggccat ttccctctct
81901 aatgaggcgt tacaagtaca tgcatgtggc aagaacagcg ggatgtatag gtattctggt
81961 caacacgctg tcgctacgta atacaagaga aactatcaac gagctggtca agcttatcaa
82021 aactcgtgag aaaaaacact atttatttgt tgtcggaaag ccaaatgtgg ccaagctagc
82081 aaactttgaa gatattgata tttggtgcat tctcggttgt agccaaagcg gtatcatcgt
82141 tgatcaattc aacgagtttt acaagcccat tattacacct tatgaattaa acttggcctt
82201 gagcgaagag gtcacatgga ccgggaaatg ggttgtggac ttcagagacg ccattgatga
82261 aatcgagcag aatttgggcg gacaagatac catctctgcc agcacaactt ccgatgaacc
82321 ggagtttgat gtagttaggg gaagatatac tagcacatca agaccactgc gagcgctaac
82381 gcacctggag ttagaggcgg ccgacgacga cgattccaaa caactgacta caagacatac
82441 cgcctcaggt gccgtcatta aaggtactgt atccacttca gcatcagcac tgcagaatcg
82501 ttcgtggaaa ggtctaggaa gcgatttcga ctctactgag gttgataata ctggagcgga
82561 tatcgaagaa ggtatttccg gtgtcgcacg tggttatgga tttgatcgcg aagacgctat
82621 gaaaaaggaa aacaaatgac tcttataatt tgtttccctc gacttctcta tttaaatcca
82681 agattttaac taataaacta tttaataata aaacaattaa ctctttatat ggaagccttg
82741 gaaattagcc gccaaaatgg gatatacatt ccgtgcgaag tgaccgcgtg gaaggccggg
82801 tatcatctta aaaatcacta gtttcttttt tagcggaatg caataaaggt gctttgtgct
82861 ggtgtggttt acacggaaca tctagtagct aaaacttggt aactcaatgg tgatcagaat
82921 ccatagaagc atttttattt cttaaaatgg gtgctgctcc ttccaaaatt gtggatggtc
82981 ttttagaaga tacaaattgt atgtacactt cggagtgagg aaaagaaaga aaggggaaat
83041 taaccgattt tactaacact gacactttga acagttgata gagatgaaat tgaaaggtta
83101 aggaagagat tcatgaaatt agatagagat agctcagggt ctattgataa aaatgaattt
83161 atgagcattc ctggcgtttc gtcaaaccct cttgctggac gtataatgga ggttttcgat
83221 gctgataata gtggggacgt ggattttcaa gagttcatca caggattatc cattttcagt
83281 gggcgtgggt ccaaggacga aaagttaaga ttcgccttca aaatctacga cattgacaag
83341 gacggtttca tatccaatgg tgagttgttc atcgtgttga agattatggt aggttctaat
83401 ctggacgatg aacagctgca acagatagta gataggacga tagtggaaaa cgatagcgac
83461 ggcgacggac gtttaagttt cgaggagttt aagaatgcta tcgaaaccac agaagtggcc
83521 aagagtctga cattgcaata cgatgtgtaa gactagggga cacttcattc atttatggta
83581 tgccaatatt tttaagaaaa gaagaataat acgcgatatt gttttttaag gaaggaacgc
83641 acactcgccc agttagagtg ctgatgatat atacatatat atatgtatat gtaacaaaca
83701 ataagaaagc aatgatacaa catagagatg agagagagca tatatgtcag cgacgagata
83761 taccaagatg gaagctgatc tcatgtaata actgcggggt gtactttgat aatttttggg
83821 attccattgt tattaatagc tttgatatca gacatacaga ataccagaga ttttcctcaa
83881 aaatatggca atgcacaaag ggggatcaat agttatataa attaagatta ttacttcttc
83941 tttgttttat gtgttgttat tcactatccc actgcattat caatccttac atatcagctt
84001 ccgttaaacc cgatgactat ctctcaatca tcatactatc ttcttacacc gtatatgata
84061 attaccagca atactaatgc taggagacag accatctttg attcctattc caataaagtt
84121 aaactgtgat attggtttat tggataagtt catatcctaa aacgtgttga caacacttcg
84181 ggagtttcca gtaagtaaaa tttgtatgga gggttggccg agtggtctaa ggcggcagac
84241 ttaagatctg ttggacggtt gtccgcgcga gttcgaacct cgcatccttc agtaattttt
84301 ttttttaatt tatttttgtg ttgcaagcgt tgatcctttc cattatgcag ccataagagg
84361 aggctggata tgaattattt attaccaata taaggagcat gtaccgttga ttttgaagag
84421 ccaattgctc caaattttgg attttgtgtt cgaaaaaggg aagattgctc caaacgcaaa
84481 taaggaggaa acccgctgat tgcactcttg gaaaaataaa aataaaaagt ggtctcagaa
84541 ttgtttcaaa agtggcactg acacaatatt tacaggcgtt gatagcttct tgttttaaca
84601 atacgattta atctcggagt agttaagcca aagaatacgt gttatccgta agaggcttat
84661 tgcacgtaat ccccagtata aattatccgc aaatcgaaga caaatgttta agaaatacaa
84721 aaatcaagac ttggacatgg cattttggtg gaagaaaaac cccaagaccc cttccgatta
84781 tgccaggttg atcatcgaac aactaaataa attcagctca ccctcgctga ctcaggataa
84841 caaacgaaag gtacaagaag agtgcacaaa atatctaatt ggcactaaac attttattgt
84901 cggtgatacg gatcctcacc caactccgga agccattgac gagctttata ctgccatgca
84961 tcgtgccgac gtgttctatg aactgctact tcattttgtg gatttggaat tcgaagcaag
85021 gagagaatgc atgcttatat tctctatatg ccttggatac tctaaggata ataaattcgt
85081 cacagtagat tatttagtct cgcaaccaaa gaccatatct ttaatgttga ggactgcgga
85141 agttgctcta caacaaaagg gttgccaaga tatcttttta acggtaggga atatgattat
85201 tgaatgtatc aaatacgaac aactttgtag gattatatta aaggaccctc aactatggaa
85261 attctttgag tttgcgaaac tgggtaattt cgaaatcagt acggaatctt tacaaatatt
85321 aagtgccgca tttactgcac atcctaaatt agtgtctaag gaattcttca gtaatgagat
85381 taatatcata agattcatta aatgtattaa caagttaatg gctcatggaa gctacgtaac
85441 gaaaaggcag agcactaaac tgttggcctc attaattgtg ataagatcta acaacgcgtt
85501 gatgaatata tatatcaact ccccagaaaa cttaaagctc ataatgactt taatgactga
85561 caaatctaaa aacttacaac ttgaagcttt caacgtattc aaggtgatgg tagcaaaccc
85621 aaggaagtca aaacctgttt ttgacattct tgttaaaaac agagataaac tattgacgta
85681 ttttaaaact ttcggtttag attctcagga ttctactttt cttgatgaaa gagaattcat
85741 cgttcaagaa attgattcct tgccgcgtat aatttcgtcc acaacagaag tttctaataa
85801 taatgcatcc tcaagtaacg tcgccagtat aacttctcca tcatcagtaa tgaacaatca
85861 atcatccatc ttaacacatt caacttcacc tgattcaaga taactataaa acttggttca
85921 ctttataaaa aatggaaagt tctcaggcag tgggtcgtga catgaatatt caaaagtaaa
85981 attatatata ggaaagtgtt tatttgcata aaaagggaaa aatagttcag acttttgtat
86041 ttttacgtat ttatacaaaa aaaggttggt accggaggct gaggaagcca gtacagttgg
86101 atccggtaca tggaattgag caatcaaccg taaatatgag cgctttctca agatattaaa
86161 ttattataaa acaatttatt tatccaattt atacatgatt tggatcctcc tttggctatg
86221 tatgttacct ctcctttcct tcttcctttt ttgttttaac ttttttgttc aagcttttat
86281 tgtttcttag taaatttgat gatgctgaac tagatggttg ggaaaatagt ggtaatctct
86341 tactagtctc ctgccctgta ggtgatgtga ttcgctgccc tttatttgca ttaaacaatg
86401 cattagattt ggacgttttt ggatcttcga tcttttcaaa aagattcagg ttagtttctg
86461 atttacgaat gatgttggat tctttagcaa ttgtcagatc tttcaacttc cgctcccaaa
86521 gtggcacctg ttgatccaag atggcattta gttcaagaag tttttcttca ttacataacc
86581 tttccttcgg gttaaacggt ccaaattggt atccgccttt accatcaaat tttaacagat
86641 agttatgaaa atgccataaa cttgtcctgt ggcaaactga tattaacgag ataccaaaat
86701 tttgcgcatt ttcgtacatc ctttgttcca tttctggggc tactgcagat gtacattcgt
86761 cgagcacagc aaacttgggt ttatgatagt acatccttgc catagctaac ctttgttgga
86821 caccaattgt taattcttcg gaccaatttc ttactatact gaatgcatca cgaactttaa
86881 tggcgcatgg tgactgattg tcttccgtcg acaactgctg tgaatcattt ttggaagtcc
86941 tttgcgccag cagaagtgac atattttcag tgactaaatc ctccaaatct aataattgca
87001 gaatttttat taaatctgca tcgcctagat cataatcatt gtgatatctt tctttgaatt
87061 gttcaatact gtctggataa ataatctgtt ccctgaatgt cgacctattg cccatatacg
87121 gcctttgggg taaataaaat attgcgcaat ctctatccac agttctacgc ggcattatta
87181 acttggattg atgattttta ttgggagtcg cccttatcgg ccaaagcccg cctagaatac
87241 gaaataatga agatttaccg caaccgttgg gcccaataat tagtagatga tttccatgct
87301 tcagatcaaa acttagctcc ggtactagaa cttgattggc aggtgttatt aaaggaatat
87361 tttcaaactt tatccttgaa tcatcatatt ccactataca cctttcatct cttggttctt
87421 tttcgtcatc acctttatta gcatccaaca aatcattgaa cttgttcaat ctcaatctga
87481 taccgcgtaa ttgttgtata tttctcttca gttccacaaa tcttccgata gagctagatg
87541 cagtgactaa taatcttcta tttgtgatga aatcagccgt catatcattc ccgggttcct
87601 taagctgtaa ggtgtcttca ctaggtttgt ttttgaaaaa tattggaatc gagcatagta
87661 ccaagccagc tgcgccccaa gtatatttaa tgacaaatgc agtagcaaca tcataaatag
87721 ctcttgcctt tatttctctg tttaaaaata gcaccaaacg gtaaaatgaa taatcaacgt
87781 tttctagttc cctcttttgc cctcttagca gtgcaatttc ttcattgctt gaatgtagat
87841 tcgagtgtaa agatctgaac caactttcca aagatgcgct tgccatagtt aacctagtga
87901 aattcggttg aatcaatttt agtaatgaat tggaggcgta gacaattaag cccagtgcca
87961 aagttccttc acccataaca ctagtgtttg aggttaataa tttgaatgaa cagaggatca
88021 aatccagcat tggctttaat agctgattca gtaataatga cgagttcatt gaaaatgtgt
88081 aaatatcttt tgtcaaatta tcctgaattt ctgaaacaga ttcagcagaa gctacggaat
88141 agaaagtatg gtgattagat agatactttg agagtagaaa gtctgaaact ttcctattaa
88201 tagtgacagc acaaagtttt gtcgtgtaac tgatcagtga attaataaaa ctggcgggaa
88261 ttccaaggat catccatttc cccaacaata tctttgtgaa gtttgcgtat tgagctctta
88321 ctagtgtgga cactaattga ccatctaaag tagccacacg aagagacagc aatgttctga
88381 tgttcagaag aatagcctgt gtaataaata aaatgaggca cttcttatca tgaagcaaaa
88441 gtttgaacaa aaaatctacc tttccttttc gctctccccc cttatgatta gtcttgcttt
88501 ctttatcaat tattattgca ccatcttctg aatctgtgct atgtttggag actatcgtta
88561 actcttcttt gctactttca tcttcctctc tatctactgc ggtttctttt ccctcttcaa
88621 ttttcttatt ttctaaaacc gttgactcag aatccttctt atcagttttg ttgttactag
88681 aactggaatt tgaattgtaa agcgtggcta gcaacaatat tatgtatgaa gaacgcagta
88741 aatttactct atgcttctga taaaatgcag aagctgttga gatcattata aaatctttct
88801 tcggtaactt ttaattgtat tattatccct tttgagtctt ttccatattc aagacgaaca
88861 aaatacagat aacaatgttg aagacgtttg ttttgtaccg gattgaggac aagatgatac
88921 ttaaatataa tattatcttt gatcgagcaa agccatcaat atcatcatct aacattcact
88981 ttactccaca tttcattgcc gcccttaatc tttcggaggg tggtaaaaac tttacggtga
89041 tagttgtaat taacgccgaa ggaatataca tcaaagacga aagaacatta attgcatata
89101 ttccaaaaat atgaataatt accaaattat tattaatttt tgttttgaaa tttaaataaa
89161 gctattaaat aaggatgatg gtgtggtatg tactataatt caatataaga gattaagata
89221 acgctgtaaa tggtttggta caattgaaaa aaagtgatag agcatttacg aaaaagaaaa
89281 aaattatgct accaaatgtg cattattgtt aacaggtcca tttgaatctt ttggtgtcac
89341 gtcggggtga cttagctctg ttctattact cgtactacct gtgacatctg tattattggc
89401 agaactactg ttgtcgatag cggttatttc attacgattc acctgttttt cgaaatcagc
89461 atcatcatca tcacccaagt tatggtcgcc gaaacggtct gcagaaatgg cagaaccatc
89521 cccatacgtg taaatttcgc ctttcctatt cgtcacagat ccggacatgt aacgaccact
89581 ccgtctgttc ctccaccacg tataaattat caatcctgtg gcgataaaag acaacgcaaa
89641 tgctgtccat atcagccctg tataggcggg accggcttta aacacaacac catatttatc
89701 atctgccgta ccgctcttta taatggcaat cataacggat atgataatgg ctgccaatac
89761 agtggctaca ccaacgcaaa cgtgtagagc tagggcaatg agccataatg gttgtttgaa
89821 catatatctg ttaaagtaca gtaatataat aaaaatcatg gtaaagaagg aaaagatgat
89881 cgctaagagg ttcaaagcca aaacagacct cactgctggc acatattggt gctctctgtg
89941 taaaagtttc ccttctaggt aaagatcgtt ggcgctaata ttcagggcgt tcagatatgg
90001 ttggaagtct gatgtgacta atgcgtcata aataatcgat ctaaaatcca agttttgtac
90061 agcatgtggg gagttacaat ctaggatctt gttttccagg ttagcatggc atagcgtgaa
90121 aatggataag cgatagtaaa tcggaatttt cagatactct agtatattcg gcgtcatggc
90181 gttcaattct tctgcggaaa tcggttggac ggatttggca tccgctaata tatctaaaat
90241 gggcaagaag gtctgagggt tttcttgagc ccaggaagtc agcgtcacta aagatgaaaa
90301 tgttgtttta ggatcagtgg atgcccctaa aagactgaag agatatggaa tgtactgtac
90361 ggagcttgaa ttaccggata ggcccgattg taattcggac aagatggaca aagtttcgtt
90421 ggtgttactc gaggagctta tcacatcatc taatccaatt agctgttgag tagattgagt
90481 tgtatttgtc accgcagcta gagattggac cgaagtgaca accattgtcg agttgtccga
90541 attttccatc aattgggtta aggcagcaaa cgcctttttt gcagatgatg actgagtgag
90601 gttttgttcc agcaaatcag atagagtgct caatgtctga tttgtagagg tggtctggtt
90661 tagcagcaat tccactgcat caaatgcggg ggcgcttgcc tgcggcacta gtggttgcaa
90721 agtactaaac gtgttattta gggaacctcc gtttgaaatt gtgttttgta actgagttaa
90781 tagtgtttgg gctaaagaag atgaaatagt agtgttcatc aaggtcgcca gagccgtcat
90841 tgtagctgtt tggttcgtgg agaaagcgaa tagcctgaat accggtaaca attgcgcctt
90901 ttctgacatt gtcagattat tcagagttag caatgcatct gtggaattct gtgggttatc
90961 ggagtctttt aataagtcca gaaccaaagt agttgagtca ctggaagagt tagagcttgc
91021 ggaagacagc gaagcagaaa ctaaccttga gaggccatct agtgtttcag ttgcgttgtc
91081 tgaatacttc agcagcccat taatctctgt caactgcctc gtgctagaag caggattgcc
91141 gctgatcgct aagggagcca attcggtcaa tgattcgatg gttactgtgg tgttgtcagc
91201 attagacaaa agcgtcaata gcggcgtcag cgcgggagta tcagcaatat ttttcatggc
91261 gccaaaaata tcatccaagg agctgttcgg agccgtcaaa gcggacccta atattgtcaa
91321 aatagggcct atctgcggga tcaccttgct tacattgatg tgtttgatat cggcttcacc
91381 gatgtatata ttcgttaagg gtttgtagtt ggcggtggag ccagcagtgg ctacaataac
91441 caatatcagt gtggtgaaca tgaataaaag gcacacagac aatatcgtcc aaataattcc
91501 cttcgacagg ggggtacggt gcttttcgat cctcatgttt ttgttgtttt ctttgctttc
91561 ctaactcttc gtatgaggat tttcgatgga gcaggatgag gagaaatagt accacatgta
91621 tatatccatt acaaaaaggt ttatatacaa ttacaataga cccttgttgg ggtttctgaa
91681 aaaagaagta gtcgatgcca tcggcaataa tacggaatta cgagaaacac aatcccgatc
91741 cttttttggg taattacttc accgattcta ccgatttatc atgccaaaaa aaattcaccg
91801 tgggttctag aagtgccctt tgaggattgt agccactcta acccacacgg cctccttact
91861 agctgactaa ggtgacaaaa ccgcaaggac tggaaagtcg ccactcatct gaaaattctc
91921 aagtttttca ctactgagtt tatgctttcg aatttttttg ttcggtaata gcacggcggt
91981 tcgattcaat tccgccgctc cgagcgatgc tccgcaaaac tcagtaataa gctttctgat
92041 ggttcacccc ttttttagca cgcggggtgt aactcaacag aaaaatgtgc catagaacaa
92101 gactaggcaa aagccaagga gcgtttgcca tgaacttcca caagtaaagc tcgttgacca
92161 gttgatcagt tgaggggggt acacacgact agcgctttca gatattaaaa agtttagatg
92221 taggttttag cggtaacagt tatataaatc gtgtttcttc tcttgatgaa acaaaaaaat
92281 gctagaaaaa ctttgtcgtt tcttactttt ggtgcgcttt gcagttttcg tggctagact
92341 tagaatcatt tctcctcaga tttcttgatt aaagtttggt gcgaagccct actctaacat
92401 tggtgttctt cttttcattc acgcaagtta agtccaggaa ggtgagcaaa tgctcatcct
92461 tctgttcatg cgtgacggct gaattatcct tatctggcgt acccgtgcag ccgtttccgt
92521 gcctcggttc ctccgagata tccttaggga ccgccaggga ccatgattgc gtcaactgtt
92581 gtcaccgctc cagaggatcc tctgtaacct tttcaaccat aaaaatagaa agggcacagg
92641 gttggggtat ttgaattttt tttttgggtt ttttcgtatt acttattact taccttcttt
92701 tctatataat tttgtttttc cctggtagag cggaatcttc ccactaaatt tttagcagag
92761 aatcctcggg tttgtaaacc atgttatagt taaaccccga tattacacca ttaaaatcat
92821 ttctaaatat gcggtcgtcg atgatcagct gcagggaaat gccaaaatat ggaccccata
92881 gaggtcttgg cttgttcata tcgttgggtc gatttctgtt cccagtgtta tttggttgaa
92941 tgggaacagt cgcgtcttgc cccatcttgt ctctgccgct ttcgtcgaat ctgactttgc
93001 aattgacgtt gcatatcaac gtgccggatc ccggaatagc gtgatagtct actcctgtta
93061 gggcatgttg tgtttgtacg acctggtttt gccacatttg cagaaaaact gttgcttgcg
93121 cgaagggggt agcattaaat attattctgc agttgtttgg attaaaaagc tgtacgaatt
93181 gggccaattt gttggagtcc ggatcatcca aatgcgctaa tatcttcttc gtaaatgtgg
93241 ccgttatttg tgcttgattt gcgtcattca ttaccatagt attactattg gtgttcatat
93301 ttctgttatt actgttatta gtttggcgtt ttgcctgacg atcagcctgg tggggccaag
93361 tatatactat aaaaacaggt tagttacttg ctctatgcgt ttgcgcatcc tctttttact
93421 tttttttttt cagtaaagcc taagcataaa tcgttttata cgtacgacac gttcaacttt
93481 tcttggttag tagtggcaat ctctgcaata catacaggga gtcatggtct atcatcttgt
93541 ccaatcaaag aagcatcggt tcagatcgag caaactgtag ggagaaagga aagtagaaat
93601 gcagagtgtg ctatatgtcc aatctcggtt ttgtagtttg gatgtcatta gagatctacc
93661 acccaaccgg ctgctttcat gtggaacaga aaagaaatcg gggcgcttcc tcttctgtat
93721 tcctttaatt aacgttttta ttcagccatc taaccatcat acccccatac ggtaacaaaa
93781 cctcttctaa gaaaagaagt ctctgctcct ccgccatctt atttttattc gctgcgcgcg
93841 tttattgtcg catcgctagc cagcaaaaag ttggttgcct ttttttacct aaaaaagaca
93901 catctaactg attagttttc cgttttagga tattgacgcc aagcgtgcgt ctgatttcta
93961 cgatatgtct ctaattttgg aagggccatt ttatttttga ggattgggct gatcattttc
94021 cttacgtgga ttgagccagc aatacagatc attattaaac tgttttgtac atgatgttag
94081 tatataatcg taaagctttt ctaatatgta taccttatac atggaactcc acagaacttg
94141 caaacatacc aaaaatcctt tattcttgtt cactcatttt acatcaaaaa ataatatttc
94201 agttattaag gaaaataaaa aaatagatta gagaagcatt ttgaagaaat agtatattct
94261 tttattgaac ctaagagcgt gatattttta ctcgaaataa aatacgaaaa atctatacac
94321 tcatctttcc gactactatt ggctcctgct caaaaaaaga gggaaaaaaa gctccaaaat
94381 tctatctttt cctatcgctc ctgtcctatc cttattacgt tcattactat tttaatacta
94441 tccattcttt tattttcagt ctaaaaaaaa catttctcat aacgggaaaa gcaaaaaaat
94501 gtcaagctta tacatcaaaa caccactgca tgcattatct gctggtccgg attctcatgc
94561 aaatagctcc tattatgaca atcttttatt gccttcattt tccaatttat ccagtaatat
94621 cagcaggaac aatatcacaa ccgataacaa tataaattca gcaagtccta ggaagtattc
94681 gtttcattcg ctcaatgtgt cgccaattct ttccccaata tctttggcta acgaaatact
94741 tggaaaaaaa tcaaatactg caccagcatc gccacatcat atggattaca atccaatttc
94801 ctcattaaca ccaggcaatt caccagaatt caacaaggca agcttatctc agattagttt
94861 tacaaatcca ttgaactatg ggtctggctt aggtttttcc tctaattcac aacctcgact
94921 accattgtta gacaggctat cgtccgtctc tttatctaag agaccggagc gcccacaaca
94981 aagcctacca tcactaaggc atctgcaatt attacccagt cctcttttac aagaaaacgc
95041 agcacgcttc cctgatacat caaaacgtac atctaattgg aaaactgatc ttacccattg
95101 gtgtaaggat acaaactatc aagactatgt taaaatacgc gaagaagtgg ctcatttcaa
95161 gccattaagt atacccaact taactaataa tcaaaataat gatagtttca attacggcaa
95221 ggaattggaa tcgactaggt cgtccaagtt ccattccccg tctaaggaat catttgatcg
95281 taccaaacta attccttcga ttctagaagc taaagatcaa tttaaagatc tttccaacaa
95341 tgcatggagt attactcctc ccgtcacacc gccgatgagt ccaccaacca atagaaccat
95401 ggagcgcacg acgcttagag gagtagaggc ctcttttttt gaggggaaat ccagcaataa
95461 cgattcaata ttcaatccaa ttattagtga aaaattggtt caagaagtta aacatcaaag
95521 acaattacgt ggaaattcat ttcccatgcc aaatgccagt cacaaaaaga cgaacagttt
95581 caaagctttg caaataaaaa aattgcttgc gaatagagac attctatcga acaattccaa
95641 atctaatgta aggaaaccat ctaagaacaa aatctcaaag caagcatcaa atgttttcgg
95701 taacactgca agacaattgg tgatgaaact cgacaacgct agttacagtt ctgtctctgc
95761 atcttcatct ccatctccct ccacaccgac gaaaagtggc aagatgagat caagatcatc
95821 ctcacctgtg cgtcccaagg catacactcc aagcccaagg tcacccaatt atcatagatt
95881 tgctctcgac tctccccctc aaagccctcg aagatcatca aattcaagca taacgaaaaa
95941 gggaagtaga aggtccagtg gctcatcacc cactcgtcac accacaagag tgtgcgtgtc
96001 gtgtcattcg agtgattcgc cctgttggag gccatcgtgg tcgccaagaa agcaagatca
96061 gctatgtaac tcttgtggtc ttcgatataa aaaaacacat acaagatgtt tgaacgattt
96121 atgtcgtaag atccccacaa agggtgaaat aaacattatg aaatccaatg gaatagacaa
96181 agaattcgtc cccgaacgca actgcgaaat tgaagggtac cgttgcttat tttgtaatta
96241 cataactgag acagtagaga attgatacat ggataactga atctctttca actaataaga
96301 gacattatca cgaaacaatt gtacatttct ctccttgtct gtgctaaata aactacaaat
96361 aaaaattcat tttctttcat tttcattcga cacgccgcgg catcttcgtt ttcttcaccg
96421 attaatttta atctgcgccg tgcagatatt ttcgcccatt tcgaagtgaa atcattctaa
96481 taacttctcc tgcgcaatag attggtcatc ctgattttta ttctgaaatc gaaaatgaaa
96541 agcatttatt gcactgaaat agcggaacct gcttctaata agcttaaaat tcaatcataa
96601 tagtgtagtt aatagaaagg acagaagaac ttttcgttcc ttggtttatc atccaggttt
96661 cagcacggct tttgtttcaa gtttaagtag gtaagatttt ttgattgttc tacaactttt
96721 tcatagtaat caaaaccttt gaatttcaaa cttactatgt ctagtactca agtaggaaat
96781 gctctatcta gttccactac tactttagtg gacttgtcta attctacggt tacccaaaag
96841 aagcaatatt ataaagatgg cgagacgctg cacaatcttt tgcttgaact aaagaataac
96901 caagatttgg aacttttacc gcatgaacaa gcgcatccta aaatatttca agcgctcaag
96961 gctcgtattg gtagaattaa taatgaaacg tgcgaccccg gtgaggagaa ctcgtttttc
97021 atatgcgatt tgggagaagt caagagatta ttcaacaact gggtgaagga gcttcctaga
97081 attaagccat tttatgccgt caaatgtaat cctgatacca aggttttgtc attattagca
97141 gagttgggcg ttaatttcga ttgcgcttcc aaagtggaaa ttgacagagt attatcgatg
97201 aacatctcgc cggatagaat tgtttacgct aatccttgta aagtagcatc tttcattaga
97261 tatgcagctt caaaaaatgt aatgaagtct acttttgaca atgtagaaga attgcataaa
97321 atcaaaaagt ttcatcctga gtctcagttg ttattaagaa tcgctaccga tgactctacc
97381 gctcaatgtc gactttccac caaatatggc tgtgaaatgg aaaacgtaga cgttttatta
97441 aaggctataa aggaactagg tttaaacctg gctggtgttt ctttccacgt cggttcaggc
97501 gcttctgatt ttacaagctt atacaaagcc gttagagatg caagaacggt atttgacaaa
97561 gctgctaacg aatacgggtt gccccctttg aagattttgg atgtaggtgg tggatttcaa
97621 tttgaatcct tcaaagaatc aactgctgtt ttgcgtctag cgctagagga atttttccct
97681 gtaggttgtg gtgttgatat aattgcagag cctggcagat actttgtagc tacagcgttc
97741 actttggcat ctcatgtgat tgcgaagaga aaactgtctg agaatgaagc aatgatttac
97801 actaacgatg gtgtatacgg gaacatgaat tgtattttat tcgatcatca agagccccat
97861 ccaagaaccc tttatcataa tttggaattt cattacgacg attttgaatc cactactgcg
97921 gtcctcgact ctatcaacaa aacaagatct gagtatccat ataaagtttc catctgggga
97981 cccacatgtg atggtttgga ttgtattgcc aaagagtatt acatgaagca tgatgttata
98041 gtcggtgatt ggttttattt tcctgccctg ggtgcctaca catcatcggc ggctactcaa
98101 ttcaacggct ttgagcagac tgcggatata gtatacatag actctgaact cgattgaagg
98161 atatatttaa ccacgacttt cgcaagagag acggaggggg tgggaaaagg ctgaatgcaa
98221 ccattgtcac taagaatttg agtgttcatg aacgagttat acacgctatt taagagtcag
98281 agaatgatga ttcaagaaaa ttctggcatt tttcctgtcc accactgtac gccattgtac
98341 acaaaagtat ttttttatat tttttttaca attttttata attttttttt atgtttagtg
98401 tatatttgct agaaagaaac aagatctttt ttggtagtgt aaatgcttaa actttgtctc
98461 tttttccttt ttactttgga aaaatgccga cgcaagaaca tagacatctg cgaaaaccaa
98521 aaataaagta ccaattgtac atacaaaaac agagaaaaag ttcatgaaca gaacgttact
98581 acggtatagc aagatctttg aatacatcca ttacttcgga ttgttcacca tacttcaaca
98641 caggccaaga tagaccatag ctacagtgat agacgaatat ttatttcaaa agaagcatca
98701 accataaaat aaaaagaaaa atgatgaaaa aaaaaccaaa gtgccaaatt gcaaggacca
98761 aaccatcggt cgaaaacgtc ataccatata accaattcaa gaagacgcag ccgcgattca
98821 acggcaactt ttctgcactg aataatgaag aatacataat actctttggc ggaggtcggg
98881 acctgatact aggctccctg acaccttgtt cgagctctca tttgtccaat caagccaacc
98941 cacaagacac cagtgagtat ggcacagacc tgtttatact caacagctgc attatcattt
99001 ggttcaatgg cttgggatat gggctggaaa ttccctacag cagcgttttg taccatgcat
99061 caagacggct accagatggt agggaagggc ttcaattaga aattttgctg actttggaaa
99121 gagacgaagt gttggacatg ctctaccaaa gcctcgcgcc acaggcctgc gaattcgacg
99181 gcgaagaagc acatgccttc accgtgcgca gcgtggaatt gactatcagg cccaaatatt
99241 caatatacga tcgccattat aacaacgaaa tcgaaaccct tttcaccttc gaaaacttcg
99301 gcgtgaacag gggcgatgac ctggtaaaca attgtaacga agcactagcc gtatgcatgg
99361 acctgcacgg tgaggacgta caagatcaag accaggaaca ataccaagat ccaagcatgg
99421 cgtttgaggg tgcgcaagat ctcaacgcca cgtattctgg gcttggagac acccttcacg
99481 ggccgcccgt gtatcagaac gacgggctgg cagacgatct ggatggcgac ctcgttatgg
99541 acaacgtggt ctctaggggt ggtccagaag caagtatgtc tatggagttc tacgcaaatc
99601 aaaatcttgc tggcagaaag aactccagag acaatgaatg aacaacatct attatgggaa
99661 catcccgctg tactatgcgg tctcgtcctc tacgaatatg gctatttgcc ttcgtatata
99721 cctttctata ccaagtaatg aatgtcttga gggcccgtat ggccgcgcga aggcttagtt
99781 aagatgtttc agcaaacggc agcatgtgaa aaaacccgta gaaggtccgc atcagccttc
99841 catgcccgtg cacccacggc tcctcggagg ccgggttata gcagcgtctg ctccgcatca
99901 cgatacacga ggtgcaggca cggttcacta ctcccctggc ctccaacaaa cgacggccaa
99961 aaacttcaca tgccgcccag ccaagcataa ttacgcaaca gcgatctttc cgtcgcacaa
100021 gttaaaagaa attgttgaaa aatacaaata atcgcgaaca atacgttgtt gctatttaac
100081 gcttttggtc tgacagtaag tgtgcctttc ccaatcaccg aaaagtgttg aacgattcac
100141 tgcgacaata atcagagatt acagtcggca ttttggcatt tttggcatac tttttatcga
100201 ttgaaccatc ttctccaaac acttttcctt tttccttcta ttctgcagga ccaactaaaa
100261 ctgggtatat atatcattat ctatatatat aaacggcttt caacaaagtt ataggggaaa
100321 actaaaaata taagaaaaaa aaaggtattg attgataagg aaaaagaacc aagggaaaaa
100381 tataaaaaag tacattgggc cttttcatac ttgttatcac ttacattaca aagaagaaca
100441 aacaactttt ttaaacgaat tttctttctt cctttttcaa tttattaatt ctttttttcc
100501 atacaattca aggtcaaata tattcttata tgctctttga atatttctga aaaatatata
100561 aagaaaagaa actacaagaa catcatccgg aaaatcagat tatagactag gattccgctc
100621 tttttagtat atttattcgc cacacctaac tgctctatta ttcgctcatt atggacgctt
100681 actccacaag accattaacc ctatctcacg gttctttaga gcacgtgctt ctggtaccaa
100741 ccgcttcatt tttcattgct tcgcaattac aagaacaatt taataaaatt ttgcccgaac
100801 ccactgaagg gtttgctgca gatgacgagc ctaccacacc tgctgaacta gtggggaaat
100861 tccttggcta cgtatcttct ctagtcgaac cttccaaggt cggtcaattc gatcaggtct
100921 tgaacctttg cttaacagaa tttgaaaact gttatttaga aggcaatgac attcacgcct
100981 tggctgctaa actattacag gaaaacgaca caactttagt gaagactaaa gaactaatta
101041 aaaattatat taccgccaga ataatggcta agagaccatt tgacaaaaaa tccaactctg
101101 ctctttttag ggccgtcggc gagggtaacg cacaattggt agccattttc ggtggtcaag
101161 gtaacaccga cgactacttt gaagaattgc gtgatctata tcaaacttat catgtcttag
101221 tgggagattt aatcaagttc tccgctgaaa ctttaagtga actgattaga actactttag
101281 atgctgaaaa agtctttact caaggtttaa acatattgga atggttggag aacccttcaa
101341 ataccccaga caaggactat ttactttcca ttccaatttc atgcccctta attggtgtca
101401 ttcaattggc tcactacgta gttactgcca agcttttggg tttcactcca ggtgagttaa
101461 gatcttactt aaaaggtgct acaggtcact ctcaaggttt ggttactgct gtcgccatag
101521 ctgagacgga ttcctgggaa tccttcttcg tctccgtaag aaaagcaatt actgtattat
101581 tcttcatcgg tgttcgttgt tacgaagcat acccaaacac ttccctacca ccatccatct
101641 tggaagattc cttggaaaac aatgaaggtg ttccatctcc aatgttgtcc atttccaatc
101701 taactcaaga acaagttcaa gactatgtaa ataagactaa ctctcatttg ccagctggta
101761 aacaagttga aatttctcta gtcaatggtg cgaagaatct agtcgtatcg ggcccaccac
101821 aatcattata tggtttaaac ttgactttaa gaaaggccaa ggccccatct ggactggatc
101881 aatcaagaat cccattcagc gaaagaaaat tgaagttctc caataggttc ttacctgttg
101941 catcaccatt ccattcccat ctattggttc cagcttcaga tttgattaac aaagacttag
102001 tcaaaaacaa tgtcagcttt aacgctaaag atattcaaat ccccgtttac gacacttttg
102061 atggttcaga tctaagagtc ctttcaggtt ccatttccga gagaatcgtc gactgcatca
102121 ttagattacc tgtcaaatgg gaaactacta cacaattcaa agccacccac atattagact
102181 ttggtccagg tggagcttcc ggtttaggtg ttttaaccca tcgtaataaa gatggtactg
102241 gtgttcgtgt tatcgttgcc ggtactctcg acattaaccc agatgatgat tacggattca
102301 agcaagaaat ctttgatgtt actagtaatg gtttgaagaa aaatccaaac tggttggaag
102361 aataccatcc aaaattaatt aagaacaaat caggcaaaat ttttgtcgaa acaaaatttt
102421 ctaaattaat cggtagacca cctttattgg ttcctggtat gacaccatgt actgtttctc
102481 cagatttcgt agctgctacc acaaatgctg gttataccat tgagttggcc ggtggtggtt
102541 acttttccgc agcaggtatg accgccgcta ttgattctgt ggtttctcag atagaaaagg
102601 gtagtacctt cggtatcaac ttgatctacg tcaatccatt tatgttacaa tggggtattc
102661 cattaatcaa ggaactaaga agcaaaggtt atccaattca attcttgacc attggtgctg
102721 gtgtcccatc attggaagtt gctagtgaat acatagagac attaggtttg aagtacttgg
102781 gtttgaaacc aggttccatt gatgctattt cgcaagttat aaacattgct aaagcacatc
102841 caaacttccc aatagcttta caatggaccg gtggtagagg tggtggtcat cattctttcg
102901 aagatgccca cactccaatg ttacaaatgt actccaagat tagaagacat ccaaacatta
102961 tgttgatatt cggttctggt ttcggttctg ctgatgacac ttacccatac ttaaccggtg
103021 aatggtccac aaaattcgat tatccaccaa tgccattcga tggtttccta tttggttcga
103081 gggtcatgat tgctaaggaa gttaaaactt ctcctgatgc taagaagtgt attgctgctt
103141 gtactggtgt tcctgatgat aaatgggaac aaacctacaa gaagccaact ggtggtattg
103201 tcactgttcg ctctgaaatg ggtgaaccaa ttcacaaaat tgccactcgt ggtgttatgc
103261 tatggaagga attcgacgaa accatcttca acttaccaaa gaataagttg gtaccaactt
103321 tggaagcaaa gagagattac attatctcaa gattgaacgc cgatttccaa aaaccatggt
103381 ttgctaccgt caacggtcaa gcccgtgacc tagccacaat gacatacgaa gaagttgcaa
103441 agagattggt ggaattaatg ttcatcagat ctaccaactc ttggtttgat gtcacatgga
103501 gaacctttac tggtgatttc ctacgtcgtg tcgaagaacg tttcactaaa agtaagacat
103561 tgtctttaat ccaatcctat tctctactag acaagcctga tgaagctatt gaaaaagtat
103621 ttaatgctta tcctgccgct agggaacagt tcttgaatgc gcaagatatt gatcactttt
103681 tgagcatgtg tcaaaatcca atgcaaaaac cagtgccttt tgttccagtt ttggatcgta
103741 gattcgagat ttttttcaaa aaagattcgt tatggcaatc tgagcacttg gaagccgtcg
103801 tcgaccaaga cgttcaaaga acatgtatcc tacatggacc tgttgcagca caattcacta
103861 aagtcatcga tgaaccaatt aagagcatta tggatggtat tcacgatggt cacatcaaaa
103921 agttactaca tcaatattac ggtgacgatg agtcaaagat tccagcagtt gagtactttg
103981 gtggtgaaag ccctgtagac gtacaaagtc aagttgattc ttcctctgta tctgaagact
104041 cagctgtttt taaggcaaca tcctctactg atgaagaaag ctggtttaag gctttggcgg
104101 gatccgaaat taactggaga catgcaagtt tcttatgttc ctttatcact caagataaaa
104161 tgtttgtttc taacccaatt agaaaagttt tcaagccaag ccaaggaatg gttgttgaga
104221 tttccaacgg caatacttct tcaaagactg ttgtcactct ttcagaacct gttcaaggtg
104281 aattgaaacc aactgttatt ttgaagttgt tgaaggagaa cataatccaa atggaaatga
104341 ttgagaacag aactatggat ggtaagcccg tcagcttgcc attgttgtac aacttcaacc
104401 cagataatgg ttttgctcca atctctgaag ttatggagga cagaaaccaa agaattaagg
104461 aaatgtactg gaaattatgg attgatgagc ctttcaattt ggactttgac ccaagagatg
104521 tcattaaggg caaagatttc gagatcaccg ctaaagaagt ttatgacttt acacacgctg
104581 ttggaaacaa ttgtgaagac ttcgtttcta gacctgatag aacgatgttg gccccaatgg
104641 actttgctat tgttgtcgga tggagagcca tcatcaaggc cattttccct aatacggtcg
104701 atggtgactt attgaagttg gttcatttgt ctaacggcta caagatgatt cctggcgcta
104761 agccactgca agttggtgat gttgtttcaa ctactgctgt tattgaatct gtcgtcaacc
104821 aacctacagg aaagattgtc gatgtggtag gtacattatc gagaaatggc aagcctgtca
104881 tggaagtcac ctcctcattc ttctacagag gcaactatac tgactttgaa aacactttcc
104941 aaaagactgt tgaacctgtt tatcaaatgc acatcaaaac ttctaaagat atagctgtct
105001 tgcgctctaa ggagtggttc caattggacg atgaagactt cgatctgtta aacaaaactt
105061 tgactttcga aactgaaact gaagttactt tcaagaatgc taacatcttc tcttcagtga
105121 aatgttttgg cccaattaaa gttgaattgc caaccaaaga aaccgtggag atcggtattg
105181 tcgattacga agccggtgcc tctcacggta accctgttgt tgatttcttg aagagaaacg
105241 gttccacatt ggaacaaaag gtcaatctag aaaatcctat tccaattgca gtacttgatt
105301 cgtacactcc aagtaccaac gaaccatacg ctagagtttc tggtgatttg aatccaattc
105361 acgtttcacg tcattttgcc tcttacgcaa acttgccagg tactatcacg cacggtatgt
105421 tttcttctgc ttccgtccgt gctttgattg aaaactgggc tgctgacagt gtttcatcca
105481 gggtacgtgg ctacacttgt caatttgttg acatggtttt gcctaacact gctttgaaaa
105541 catcgattca acatgttggt atgatcaatg gtagaaaatt gataaagttt gaaactagaa
105601 atgaagatga cgttgtagtt ttgactggtg aagccgaaat tgaacaacct gttactacct
105661 tcgttttcac tggtcaaggt tcacaagaac aaggtatggg tatggactta tacaaaactt
105721 ctaaagctgc tcaagatgtt tggaatagag ctgacaacca tttcaaggac acttatggtt
105781 tctctatctt agacattgtc attaacaacc cagttaactt aacaattcac ttcggtggtg
105841 aaaagggtaa gaggatcaga gaaaactatt ctgctatgat ctttgagact atcgtggatg
105901 gaaaattgaa gactgaaaaa attttcaagg aaattaatga gcacagtact tcttacacat
105961 ttagatctga aaaaggttta ttgtctgcta ctcaatttac acaaccagct ttaactttga
106021 tggaaaaagc tgctttcgaa gacttgaaat ctaaaggttt gatcccagcc gatgctactt
106081 ttgctggtca ctctttaggt gagtatgctg ctttggcctc tttggctgat gttatgtcta
106141 tcgaatcttt agttgaagtt gtgttctaca gaggtatgac tatgcaagtt gctgttccaa
106201 gagatgagtt gggcagatcc aactatggta tgattgccat taacccaggt agagtcgctg
106261 catcattctc tcaagaagct ttgcaatatg ttgttgagag agttggtaag agaaccggct
106321 ggttggttga aatcgtcaac tacaacgttg aaaaccaaca atatgttgca gctggtgatc
106381 taagagcttt agacaccgtt accaatgttc taaacttcat caaattacaa aaaattgata
106441 ttattgaact acaaaagtcc ttatctttgg aagaagttga aggtcatttg tttgagatca
106501 ttgacgaagc ttccaagaaa tctgctgtca agcctcgccc acttaaattg gagagaggtt
106561 ttgcttgtat cccattagtt ggtatttctg ttcctttcca ttccacctac ttgatgaatg
106621 gtgttaaacc attcaagagt ttcttgaaga agaatatcat aaaagaaaat gtgaaggttg
106681 ctagattggc cggaaagtac attccaaact tgactgcaaa accattccag gttactaagg
106741 aatatttcca ggacgtttat gatttgactg gctccgaacc tatcaaggaa atcatcgaca
106801 actgggaaaa gtatgaacaa tcctaatttc ttaagtgatt atataaccgt aagaaatatt
106861 taactttgaa actcctgtat actaatgttt aatatagctg gcttatgatt ttagttctct
106921 tctcctatta taaatagata cattgattag gtatttttat aatatacttg ggattaacag
106981 atgctatatg aatttttttt tccgccgcaa gccctcgcta gggcggggca gatgctgaag
107041 aaaaaatttt ctgttccatt gggttatgtt taaaaatcaa cgatattcga acataatcga
107101 tgaccttgat gattagcgaa gttctgctct aaagaaatta gctttaaaaa cagctccatt
107161 attagtgtaa actgctactt caactcttta ctcgaaaagt tgaaacaagt gtctattccg
107221 cacatctctg caataaccga accttcacga tttagctaca atcccacatc tgcagattct
107281 accgtttaat agtcttaatt tgaagagaaa taaaaatgcg taagtgtaaa atttttgttg
107341 gtaactctca cccagagttg ggtaatatgg tttgccaaag attaggtatc gaaccagctc
107401 catgtacatt aaaaaaattt gcaaatggtg aaacgtcagt tcaaatcggt gtatctgttc
107461 gtgacgaaga tgtgtatgtc attcaatctg gttctccatc cataaatgat gacattatgg
107521 aactgttgat tttagtttct gcctgtaggg gcggatctgc taggaaaatt acagcagtca
107581 ttcctcaatt tccttactct aaacaatgta aaatgaagag acacagaggc gctattactg
107641 caaggatgtt ggccaatctg ttggtcatgg ctggcgctga tcatgttgtg tctatggacc
107701 ttcatgcttc tcaaatgcag gggtttttca ccaaaccagt cgataaccta tacgggggcc
107761 ctagtttagc gaaatggatt agagaaaatg ttgaagacta tgaagatgca gtagttgtct
107821 ctaagaatcc aggtggtact aaaagagtta cagccctggc ggattctttg aagatcaact
107881 ttgctatgat ccatactgat cgtcgtcgtt ctaaggatct gtattctcaa aacaaggatt
107941 tgcaacaact aaagttgaga aagcaatcaa tgttgaggaa aaatagaccg atcatcagac
108001 aaggtgacca tccaaatgag gaggaaaaca ttattttaag taacggtatt caaactgcta
108061 ggatccgtaa cggccacgtt atcggtgacg atgaggcaga cgatgatgaa gacgctatct
108121 tagaatctga cagcgaattg cattctattg atggcttaga ctcgcatggc ttgggcggta
108181 catatgatgc tgtcgactcc gaagacgaag aggaaatccc agttctctat agggaacaac
108241 tgattacatt ggtcggaaac gtccgtggtc gctctgccat cattctagat gatatgattg
108301 atagacctgg gtcatttatt agcgctgctg aacatttggt gcaaaattgt ggtgccaaaa
108361 aggtttatgt tgttgctact cacggtatat tcactggaga ctgtttggaa gaacttgaaa
108421 agtccgatgc cattgacaca attgtggtca caaatacata tccgatttct ggcgaacgca
108481 tagctgggtc caagaaattg gttactatcg atgtttctcc aattttcgca gaatgtatcc
108541 gtcgtgatca ttatggtgag agtatttccg ttttatttga ctctttggca gctctgtaaa
108601 cagaagagag tgtgcgcaat attttagttc ttaaatatga catagattat caaaaaactt
108661 tgtatgtttg ccagatttca gtgaatctgc aagagtataa attataggaa tttgggtgaa
108721 ttaaaccatt tattatgttt tatgtatcat ggaaaaaaca gaacctttat caaatcatct
108781 atgaaatttt gacaggttag ccattttcct cattttattg ctctgcaata gtaaattata
108841 tagatttatg caatgctcta ggttccggcg gcttttcatt taatgtgaac tcaagactat
108901 tatcatccaa acacattaca acatccgtac atttagttgg ctccattttt tgaaaaaata
108961 cttccgagta agatgctgaa agtaatcaaa ttccgtgaaa aaggaaccga tttggtaagg
109021 gcggacctgc cggaagaaaa tcgctcccgc gtgtctactg gactttgctt ctttgccagg
109081 cgggagaatg aagcccaccg gcctagctct atgggcgcag acagggatgg tctcgatttg
109141 ctttctcact gcaatggaaa tttctaacat tagagcttca acggctagca taaaacaact
109201 actaacgttt tcagtgctat attcgaaaga gcaaacaaag agtcctcaag aactactaat
109261 agattaaaat ggctagatac ggtgctactt ccactaaccc tgctaaatcc gcttctgctc
109321 gtggttccta cttgcgtgtt tctttcaaga acaccagaga aactgctcaa gctattaacg
109381 gttgggaatt gaccaaggct caaaaatact tggaacaagt tttggaccac caaagagcta
109441 ttcctttcag aagatttaac tcttccatcg gtagaactgc tcaaggtaag gaatttggtg
109501 tcaccaaggc tagatggcca gctaagtctg ttaagttcgt tcaaggtttg ttgcaaaacg
109561 ccgctgccaa cgctgaagta tgtcaagaat attatatgtt tagtaccaga tgaaacaaga
109621 atgagttgaa attcaaaatg cgcggaaaat ccattatgat caagggaaat tgaatatgat
109681 aaatgaatta ttcagaaagt cacaattacc agattggaat gaactgtcaa gctgaaaagc
109741 aactaaggat taccattacg tgtttatgat tttgttagaa aaatattgaa aacttgatat
109801 ttctttccgc tagtttcatc tttttcaatt acttaaccgg atcaaaattt tttttactaa
109861 caacataact atttttatta caggctaaag gtttggatgc tactaaattg tacgtttctc
109921 atatccaagt taaccaagct ccaaagcaaa gaagaagaac ttacagagct cacggtagaa
109981 tcaacaagta cgaatcttct ccatcccaca ttgaattagt tgtcactgaa aaggaagaag
110041 ctgtcgccaa ggctgctgaa aagaaggtcg ttagattgac ttctagacaa agaggtagaa
110101 tcgccgccca aaagcgtatt gctgcttaaa tagaagatga aaaataatga taatataatt
110161 ctctgttaat tttaatcttt tatctatgta attttatctc cccgtcatat cacataactc
110221 taaaataagt tttttattaa tattattata ttatatcgga taatcctacg ttcaaagtat
110281 tgaacatagt tttataatga acaaaggtat aagaaatgct cataaactga aaaaatcccg
110341 tagataagat aataagaaat gctactgtct atatcaatat gtcaatcgtt actcattccc
110401 tctctagtac ggaacgtgtg cgttcttcat accgagctat tagaatttag tgaataaagg
110461 catctatcga tttatgccat gaactgaacc aacgcctgca gctacttttt ctgctccccc
110521 aagtcctccg ttgagatttg aagaagactt tgccgattgt actataccaa cctcaggtgt
110581 catgtagccg ctaatattaa tcacatacat gctcatcatg aatacgagtc cgtgtaaacc
110641 gatacagtaa aagaggaata ccatccttgt cattttattt tgtaaaatga cttttgcaaa
110701 actggaaaat aacttctcta aagctgataa tttcttgttt ttgtagtggt ttaattcgtt
110761 ctgtctaaaa tttgccattg gatgcaacga ttcatcatac acccttgagt attgggattc
110821 cacgtcaata cgctctgtac tttgattaac gggagcgttg ttattattat aggattgcag
110881 atacctaatc cgttcataaa gcttcgtatt gtcgcctttt agcttcgaaa tttctagttt
110941 aagcttaccc ttttctgagt ttccttgtct tagttgcttt tccagatcca tatttctcga
111001 acgaaatctg tctctttgtt tagtaactat tggtaaaatg gttgattggt ttccagaaag
111061 ttccccatct tctggaatac caataataga actcgttggg gacattttat gggacgtacg
111121 attgttcatt tgtcttgtta caccagacat catacttgca gtctcgttga agtgaggact
111181 gacgttctct actttttcta ggtccgtctc taatttttca tttgcttctt tgagagtagc
111241 tatttgctgc ttcaattggt ccacagattt tttcaattcg tttcgttctt cctcttgagc
111301 cgtacttttt gagcggtatt ccgccaaagt agcctggagc ttcttatttg cagatagtaa
111361 ggaactttcg aaagtattat cattcttgtc ttcagagcga atgtcattat cagaatcatc
111421 ttcgtttacc ccaaactcaa tttttttcaa tgcagaaagt tcttctttta tcttattgta
111481 atcagaataa ttgtttagtt ttcttctaac agtttctagc tccgacttgt aagattccga
111541 ttccgccaca acgctattta attgttcttt taactcattt attgcatgtg atgttgattt
111601 ccgttcctgc tcataggatg cactcaacaa tgcattttcg ctttccagct ggttaagttt
111661 tagttccttt gcatgtaact cagtttcttt ttctgcttca ctagttgcct ttgcaagagc
111721 accacttagt tcctcatttc ttttctctaa ctgatatatt ctagcctgcg tagtttccaa
111781 ctcctgtgtt actagattat attcagcaat ccttgtagat acttcttttt gattgttttc
111841 ttggtcacca tcttcgtttc cattaccttc tatatctata tttttagata ttttggcctc
111901 tagtgccttg ttttgctcct gtacatttgt taattgtttc aatagatctg cttctctctc
111961 tttccaattt cttccttttt cctcccaggt agaattgatt tcttgagttt tcgcagtcag
112021 tctttttgcc aatgtttttg cagagctttg ctctaggtcc agtaaccttg atttcaaagt
112081 ctcataatct gcatatttgg ctagcttatc ttctaggtag cttatttttt ccttaagttc
112141 cttcgagtca tcaattttgc ccaatttttc caacgaactt tgtagtagcg gctgtggatc
112201 aggagcctct gaaagctttt cgtatacgtc aaaaagaacc ttttcagaga attttgatct
112261 ctgtgtcaaa ttatcaattt cacgttggta ctgcttaatt attttattca cattgttcaa
112321 tttttcctca ggttcgagtt ttttaaattt tttagtctca gtggctaatg actttcttga
112381 attcaaggac agggtttctt tatccttaat ctctataaca tcagcatcca attctctttg
112441 aagattcgtt aaatctgcct tggcccaaat atccaatgca tgagaatata ctgacgtatc
112501 cattgtcaaa ttatttttga cgagctaata taacagagtg aagaaatgaa gcaattacgc
112561 acaatttatt gtactgtgtt cattcaaaac tcttaaacat attattttgg cattttcatg
112621 agccccaaga taatatcatt tgttacgtaa cattctctat gacagtaatg gttttcttga
112681 atgacacaag taaccactac aacttggtgt gcagaatagt gatagagcga actgaaattg
112741 tgggtaccta aatattcttt gattatgagc ggagatatga tgctctttca tgttttcctg
112801 gcctgaattt tggtatgctc ctaaaaaaat ggccaattaa gtgatcgtgc caattctctc
112861 gtttattaaa gactgttctg ctaatcgact tttggagcaa aagcttactt ttgtttcgag
112921 cttaaaaaat ttttcttgtg tggaacttgt atcaatttct ccttatattt atatataata
112981 cagacgttat tgcttttcta tagaaaaaaa tagaaaccaa agtagcaaaa aagcagtaaa
113041 tattaaagta aagtttacac acaattcgtc atttttaccg ctaagccaca tattagctga
113101 tgagctcatc gttacattat ttgagccaca attcactaaa aagcagtatt tcaatcctag
113161 tcctgtaaaa ataaaatact cctagtccag taaatataat gcgacactct tgtgttaagg
113221 gcctgcagta ttttctgaac tatgttcgtt tgagcttgaa ttctcttctt ttgaagctgg
113281 agagtagcaa agactttccc cttcaaaatt ggagcttgca gaattatgaa gcttttctga
113341 ataatcgaga gtaacttttg agaatcctcc aagtgatatt tcgtcgtcaa agctctgtcc
113401 ttgcgtgacg taagggatgt gcctactttc ttttaggtct atttcatcaa gaatatcatc
113461 tgtttcttta tcagcaaaca aatatttttt gcttttattt tgagattttc taggatcatc
113521 tggaatccta tagtcgacat agaaatgcgc ttgtgatatt ggtgtaccta cacagggaga
113581 atagttttct gtacacgtgg agatatagtt ctcagagtct gtagaaaatg ggttacggct
113641 ctctttgcgt gaggacagct tgtttagcaa tatgcctact cgtttttcct tattcttatc
113701 aatgaatctt ttccacatgt caagtacaaa tcctagtttg atggaacgca ggaatttaga
113761 gtacatatgc aaagcatcag aacctaagcc aaagattaga aatactaggt aagacatcaa
113821 aacataaagc catatattat aaattggtct gccagggtca aatttaataa tggtattcca
113881 gatggtgctg gaatgggtat ttttaaaagt atagtgtcct tctacctgct gtaaatcttg
113941 aacaaaggtg taaacagaaa aagggaacat gactaaaata ataatgaaac agaatatcaa
114001 cagccttgcg aaccttgtca ggtttaaacc tgaattggta cagtgtaaaa tatccctaac
114061 gtccttgcgt tttttataaa acacgaacag tactaaggtg gcataaacag cgcccacaaa
114121 tgaccatata agcatccaca tggtatacaa aacagtggta atccatgtcg gagacaataa
114181 gttttggcaa ccgttgtaac gagcgatacc atatctaaat acttgtaaca gatatgaaaa
114241 tcccatgacc atgacaggtg tgaacaagct aatcacaagg tccttgacga ttttcgtcca
114301 tgatgaaaga tccggtaaaa cactatctgc cttcaaaatt gtatgcaagt tgtaaatgat
114361 gttggtaacg gcacatgata tgccaatatt cgcaccaacc tgcaacttga tgacaatatc
114421 acaccaacct ttaccatccc atctcgtgag gaaatcgtcg tcactccata ttgccgcatc
114481 tacaatacac gttaaattca ttgtaagaag ccatgttatc aaaatgattg ctggaatatt
114541 cttggtatgt gaatgccatg ctaaaggggg agctaatagt atcacagcta gcaaacaaag
114601 ccctattatt gctgacttgt atgacatgaa aattttgata gtattttgcc tttcctacac
114661 aaatttaatt gcctctaaag ttaaaaagca ataaaataga atatgtgaat actgcacaaa
114721 atgaatactt gggaattcag aaattattct taccttaagc atccactcat atacatatat
114781 atatatatat atgtcttttc aaaagacttc tgcccaaatt gtggagagaa ctctgcctct
114841 ccgtgataac ggccaaatga aacgcatcca atgatgcaat tattgacaaa gtttcaaagt
114901 ttccgccatt attccttcat ttacacattg atagtcgaga agtttcctaa ttagtgtcac
114961 aatgacagag aaaattgtac cagcgcttct aacgaaaatt agcacccata cccagagttc
115021 ataaatctgg caatgtggta caataatata ggattggtaa catttcaatt gtaaaatgtt
115081 taacgtttag agaaaagggg agccagaacg cttctggtgg tgtaaatacg gagaagtcac
115141 cttaaatagt tttgttctga taattgcatt tttttggaaa gatttggctg cttaaaagat
115201 tcaagcaatc aagagaaaca ttacaaggcc tgcttggccg gtctactagg ctgaaataat
115261 aagtttctga ttatggttat cacggtaaat gattacgaaa gggtaaagca acgaatggtt
115321 gttttatggt aagaatactt tggcgaatca acaaattgaa gttgcgcaat gtgcgattcg
115381 cttatgtatc aaaaaaaact aaaaaatgaa tagagaaaat catatatata aaagaaaaaa
115441 atatcgtaca cctcttaggt aacttggaat atattaaaca tgtaaagaag gagaaaacat
115501 taacctgcat tacaataatg aacaagagat gaaaaaatcc gtaaagcttc tgaatcgcga
115561 agctcactat ctattccatt atcatcatat aacatcattg cactctttat actattttca
115621 acaaaattaa cgcagttttc caaactagta cttagcttgc caatcttgcc acaggaaaag
115681 atttttctgg tcttctgttt caacacgtac ttcctttttc cgacaaaatt ctcatcatag
115741 atattctggt tgctgttatt gttgttattg ccagtaaact ctcttttcaa tgcgacatcc
115801 ctaatgtccc ttgaacgtaa cgatactaat agacttcttg tgtaatccgc ctttaacagg
115861 tcaatcttca tagaatttgt tattctgctc tctgattctt gaccagcagg acatgcttgc
115921 aactggaaaa aattgttaaa atgggttaaa tacattgtat atttcggcaa tagttccaga
115981 ggtttattca tcaagccatc atcaatatca gaatcagtag tcaaaatatc cgcataagaa
116041 gagttacctg gaaaaatttc gtaagtggaa ttaaggtcag ccaaagaggg ctgacatatt
116101 ctttcaaaag cctcatccaa aagatcatcc tgagagatcc tttggcaatc tcttttcaac
116161 tcaacgttct ttagtggaaa tttatatgat atattcttaa ccaatggggg tgcgtgagac
116221 acatctccaa cattaggaga gccaggtgtg cccatccaag gatactcatc atattcgctg
116281 atagacggtg attgttgcgg agtggttagt gataacctgg aggttgcttg ctgcaaagaa
116341 gacgaacttg aagtcctttg catatttcca gcagttgttt gcagcctctc ccacgactcg
116401 ttgtgtttta aagaagggct tggttgaaag aactgagaaa ttgttggcct tttgttgaac
116461 caagaaccgt acgaaccagg ttggcttgag atagaagacg atagataatg caatgaacta
116521 ctcccacttt tgaaggaaga tggctgaata acttccgcta aagactcact agaagacaca
116581 gatactgaag tgttcgagtt cctccgattg ggtatttgcc atcctttcct caaagaatgg
116641 aaattgggtg atccaatgct gttagagctc acattactgt tgttgtaatt atgattgcta
116701 ttattttctg tgcgactcaa aaggttgtct gttgaagtca gtgtgctcaa ttccgtctca
116761 ggcttatcga caaaattatt gttagactta tttcttgata cagcggacga atccgatctt
116821 atgttttccc gccgtatcgt tatttgtccc ttgtactttg gctccaataa agccgataag
116881 atgaacagta acttgttagc aaccaccatg tttcctgaca ggattacgat cttggatgtc
116941 tttagttctc ttatagtgtg cctgtaatca gatataatca ttgccattag gagaggaagg
117001 aagcctagtt tcggtccatc tttgatttca atccaattaa atatactttt gaaccaaacg
117061 tgaacgaatt ctttaaatgt ctcagggtaa aggaaaagcc taggaatctc agacatagaa
117121 cgtaaacctg gtatgactct tttttgtaaa gtttgcacca ttatttcaat ttccttggga
117181 taatgcgtcc tgatgtcaat atttgacaat tttatgactg aattattgct gtaattgcca
117241 gtattttctt gcataatacg gtttttagtc aagaaaccaa tgagcatttt ttgagtctgg
117301 gtcaaccatg atgaaatgga agaccacgac tctgcaacta cgggcaacaa tatcctcggt
117361 atgcataagc taattgcgat gcggttgtat tggtgtgtgt aatagaaaat tctagttatg
117421 agtaccaaat ccgagttagg aatcgtcctt atcttgtcgc actgcgtcaa atcggaagat
117481 cttacgggag aaccaaatat atattccttc aattcactcg gccgtatctg ctccatcgaa
117541 tttgaaatct ttgacgtagt gtaatcgaag atatcacggt agttgttcct acacgccatt
117601 tgacccgctt cctcaatgat caaaatcctg aatgcatacg ttttttcgtt aatagacgtg
117661 attttatcag taccaagacc tccgttgttt tgtaacgtat cgataggacg actataagga
117721 atatccctcg agccgaaaag cttcagtttt aagtcatccg atatatgatc taaaatgggc
117781 ggagaagtcg ttgatagcat ttccgaaggc ttttccacat tgactgcagt atctaaaaga
117841 gctccagcag cggtcttagt agttcctgtg cttgccgctt tgcagtatac agggacattg
117901 ggaactacgg aggaaaaatc ggaatgctct gagctcttct caaaaccaga cgaactcgtc
117961 ttatttctca gtaaattacc caacatataa actctccctc ttcaccttct ctacaaggcc
118021 acacacaaga cagttttaac aggcaaatgg tactggaggc tctcaccaat ggggtttaag
118081 acgctccaaa cacacgctct cctttttttc tttatatatc ggtagcaacg aaagctagtc
118141 gcagaacgtt acacactaaa gcagatcaat caatcaatcc tgagaacctg cttcgttcaa
118201 accatccact agaagaaaca cgcacgtgta cccaaaaata gagacaaaca aacagacaaa
118261 aataacaatg attcctaccg actaaagtaa aacaacactc acgtaataaa aaatcctaga
118321 tacaactcac ttgtattcct ctcttctttg accatcacta aagcttctct cttactatat
118381 tcctcaaata aaaaaaagtt gcaatgatta cttaccaatg tgccataaac tccgtgcacc
118441 acactagcct tcgatttgac acatctctaa gctgaaactg agaatactgt tgtaaaacag
118501 gtattggctg cttcatagta cacccaattg cccacaaccc aagttaatca taagctcttg
118561 ttgtcgatga attgctcaaa atgtggccat tctttcaatt ttgcacctct aaaactgctc
118621 cgtgggttgt gacaacaacc ttaagggtaa tggacttttt tagaaagaca aatgagatga
118681 tttcacctac tggtatatca tttatttata cacgaccgtt ttgacatttc agagttgcac
118741 gttggtatat cctaatattc tcacaagcat cacagtgaag aaacgcaaga aaatggaaaa
118801 aattcccagg tggttgttgt tttctcttat atcgtcggtg ctgtgcatac ttggggccct
118861 gtgtgtgccg ttgttatcgg ttgccttcga tagcaagcgc aatagccaat ctaagttggt
118921 caactatggt ctttctctaa gtgccggatc tatgatcact acttcactat acatgctatt
118981 gcctcggatc gaaaaatcaa accggttcaa ggtttttcct ggattgcttt tgggtatttg
119041 cctcagtttt ttcttaaact acctagtcca cgctttcgcc agcgaatcgt tggtacactg
119101 tgctgatagc ggtgaccatg ctacaggttc acatatacac tccaaatcac attcgcattc
119161 gcactcacac tcacatgcgg attcgcattc gaattttagc aacgatcatg atttagaaaa
119221 tgctccctct gagcatggtt atgcaacatc ttcttccagt gtttctgaaa atgacccgtt
119281 gattacaaag gatagcgata gaccccaaat gaaaaagaaa atgtccctaa ttgacttatt
119341 aaccagaagg aaatcagaag gcgagtgttg tgacctaaac aagtgcactc cgctcttgca
119401 atcagagcag ccagaatata ttgcatgtgt cccaccagtg ataaagtctt ctcaaagtga
119461 aagaaacgtg ccacatggat gcgagggatc agaagataat ggacaatccg atgacaagga
119521 tcatcgtggc cttgtatgcg tggaaaataa tatcggttac gatcttgaaa acctatcgtt
119581 gtaccgtaag aattttcttt cgagccgcca tcatcattcc tctgaatcgc ccgaaaatta
119641 tggttccaac cagttgtcgc actctttttc gtcacctttg ggaaatgatg taactgagaa
119701 tccggccgca ttggcagaca cacaatacca tcccgaaaat ggttcattat acccccacca
119761 tcatcactta gagacccctt tttccaaatt actgtctatt ggtatgcaaa cttgtctagt
119821 ccttgcatta cacaaatttc ccgaagggtt tattattttt tacactaaca ggtcagattc
119881 gtcaaagtcc ttgggatttt ccattttttt aagtttgacg atccataatt ttgtcgaagg
119941 atttgcaatg acgttaccat tctacactgt tttcgaatct aaatgggttg ccattttgat
120001 tactgccgtt ctcggtggtg gatctcaacc attaggtgca ttgataggtt atttcatctt
120061 taaaggtagt actccaaggg atcacgaacc caacatggat tttttactga gcgttactgc
120121 agggttccta ttagtaattg gtttacaaat gttccaaact ggtatcggat ttagcgatgg
120181 acatcatcat catcaaggag aaggtgatga agaaatgaaa cagtcccata gctcaggcac
120241 aacttgcttg aaatggtgct gcactggcgt tttgctaatt ctagcgagtg cccttttcac
120301 ttgataaatt aaaactacgt atattctttc tatataagtc ttttcccatt aaataacggt
120361 gtataatcac gatcatatat catatatcat atctacgatc atcggcaaga tcaaattctt
120421 gttctgctgt atggtgctca tcaccataat cggttatcac gttttcctca ttttcctcaa
120481 agggattttc tgtactactt ttaggatgca ccttgatgaa accttcttca gaattatttt
120541 ctacagactc tttcactgtg gttcccgagt ttagagtatg ttcaacattg ctatcctcta
120601 gttcaaaaac agtttcttcc gcatcactgg gaattggagc cttgatgtca tctgccaagg
120661 gtaatctaaa attatacttc ccccatttga aataaagacc agtgataact aaaatgcaga
120721 atacgtacac cattaaagca taattcattg ttttgaaagt tacaggcact tgcgttggta
120781 ggcaaacaga aaccatagat aacaagagcc acacaataga aacaatgttg atgaaccaac
120841 caaacttata cctgattttt actggcgcgc ttcggatagc tcttcttctc gtaaacagca
120901 ccaagactaa cggaatgaaa gtcgcagaac aaagacagag cactgcagcg cctataaaag
120961 cattaaatgc ggccgttgaa atcaaagcta gcagacctaa aaagtatgat attatcatac
121021 tcaatacaac agaattcttg gggacttttg actgagaatc cggttcgacg taggtccatt
121081 tatcgtagta tggtatagcc tggtcacgac taaaactata taccgcacga gaagatgtag
121141 taatcgagcc aattccggaa aacagtaagt ttcctaaaat taggagcact aaaaaaaaag
121201 acaagaccac cgaatcagtc gattttgtaa aaatgttcac tattggtaga accttatgat
121261 tggtaaaaag caaatcatta tctggcagga ttaacattat tggtataaga aaaatgactc
121321 cagagaacgc ggataacaat accgcattcg acataccacg tggaatatcc ttctcaggaa
121381 ctttgacttc gtcagctaaa gcaggtaaca tactgaaacc ttgtaacgtg aaattagact
121441 gttggaatcc aatgatgaag gaaagaaatg cgcttttata ccctgataga ttattatcaa
121501 agtgaaatag cgcgtacttc aaagatcgaa atttaccttt gtggaatact agtagaagaa
121561 tatcaataaa tataatggca tatatgatcc aataaacaca gactttgttt attgtttcaa
121621 taaatcttgc aaatttcaaa ttcacgaggc ctacaacagt cacaactaag taaaatacaa
121681 tgactgtgta aaaaatcaag tgtgcctcgg atattaggtt ggagttcgtc atcagaatca
121741 aagaaatggt aagttgagcg cctgcaaaag taatactggt actcatagtc caattcccta
121801 tgagcattaa ccagccagtg taccacgaac atactaattt caatttctcc ggggccaaca
121861 tggcactccc aacatgcagt tccatcggaa attttgaaac aatctcacca agagaaagcg
121921 acgaaaacca tatacacact ccactgatta aaaaacctag cattatagtt aacggaccac
121981 cattaattag cccaatggcc atactagtgc acattcctaa aacgggactc attagtccta
122041 aaccgagacc gacaatagaa cctcttgaca ataacgattt atccaacacc tgatcataat
122101 tgaaatgctc ggcctcctcg ttctcttgac tgtcatcttc atgaacaatg gtgtgcaagt
122161 tatcaaacaa accattcgga tcgaaatgaa cgatattctc ccttatatta tcagccagta
122221 gcgtatactc tggcattttt catttatttg acttattttt atttatttta ttgtacaatg
122281 gcaaacaaat acacggactg gtatgttctt cgtcaaattg atgatctgtt cttttggctt
122341 atccttatgg gatgattaat gattgttaaa gcctcattgc ggaaatttta atgccggaaa
122401 ggcctgaaaa atttcaaagt ggcagaaaac aaggctttgg ggcattactt gccaacggct
122461 gacgattgct agctgctttt acagaagcga tacacaatag ctcctaacat agcaaaatgg
122521 aaggtgacga tttattcgat gagtttggaa atttgatcgg agttgatcct tttgactcgg
122581 atgaagaaga aagtgtgctg gatgagcaag aacaatatca aaccaatacg tttgagggga
122641 gcggcaacaa caatgagatt gagagcagac aacttacctc gttaggaagt aaaaaggaac
122701 ttggaatttc cttagagcac ccttatggta aggaagtgga agtattaatg gaaactaaga
122761 acacacagtc accacagact ccactggtag agccggttac agaacgaaca aagttgcaag
122821 agcatacaat ttttacacaa ttaaaaaaaa acattccgaa gactagatat aatcgagact
122881 atatgttatc aatggctaac attccggaga ggataataaa tgttggtgtc attggacctc
122941 ttcactcagg taagacctct ttgatggatc tcctagtaat cgactcacac aaacgcatac
123001 cagatatgtc taagaatgta gaacttggat ggaaaccgct aagatacctg gataatttga
123061 aacaagagat tgaccggggt ctttccatta aacttaatgg ttccactcta ctctgcaccg
123121 atttagaatc caagtctaga atgataaact ttttggatgc accagggcat gttaatttta
123181 tggatgaaac ggcagtcgca cttgcagcaa gtgatttggt tttaatcgtg atagatgttg
123241 tagaaggtgt tacatttgtg gtagagcaat tgataaaaca aagtattaaa aataatgtag
123301 caatgtgttt tgttataaat aaactcgaca gattgattct agatttaaag ttgccaccaa
123361 tggacgcata cttgaagtta aatcatataa ttgcaaatat caattccttt acgaagggaa
123421 acgtgttttc accaatagac aataacataa tatttgcgtc tacaaagctg ggcttcacat
123481 tcactatcaa ggaatttgtt tcttattatt acgcccactc cataccttct tctaagatag
123541 acgactttac cacaaggcta tggggtagcg tatattacca taaaggtaat ttcaggacaa
123601 aaccatttga aaatgtagag aagtacccga ctttcgttga atttatcctc atcccgcttt
123661 ataaaatatt ttcctacgct ttatctatgg agaaagataa attaaagaat ttgttaaggt
123721 ctaactttag agttaattta agtcaagagg ccctccagta cgatccgcaa ccttttttaa
123781 aacacgttct acagttaata tttaggcaac aaaccggtct tgtagatgcg ataaccagat
123841 gttatcaacc atttgaatta ttcgacaata agacagctca tctttcaatt ccaggaaaat
123901 ctacaccaga aggcactctt tgggctcatg tactgaaaac tgtggattac ggtggagcag
123961 agtggtccct tgtacggata tactctggac ttttgaagag aggggataca gtacgtatac
124021 ttgatacatc acaatctgaa tctcgccaaa aaagacagtt gcatgatatc tcaaagacgg
124081 aaacctccaa cgaagatgaa gatgaagatg acgaaacgcc ttcatgtgag gtcgaagaaa
124141 ttggcttatt aggtggcaga tatgtctatc cggttcatga agcacacaaa ggacagatag
124201 tattaataaa aggtatttca agtgcatata ttaaatccgc gacgttgtac tctgtaaaga
124261 gtaaggagga catgaaacag ctaaaatttt tcaaaccttt agattatatt accgaggcag
124321 ttttcaaaat tgttcttcaa cctttactgc caagggaatt acccaagtta ttggatgccc
124381 tgaacaaaat ttcgaaatac tacccaggcg ttattattaa agttgaggaa tctggagaac
124441 atgtaatact aggaaatgga gagctgtata tggactgttt gttgtatgat ctaagagcga
124501 gttatgcaaa gatagaaatt aaaatatctg atcctttaac tgttttttct gaaagttgct
124561 caaatgaatc gttcgcttca atacctgtaa gtaattcgat atctcgcctt ggtgaggaaa
124621 atttaccagg tctgtcgatt agtgtagccg ctgaaccaat ggactctaaa atgattcagg
124681 atttgagcag gaacacattg ggaaagggtc aaaactgctt ggatattgac ggaataatgg
124741 acaacccaag gaaactatcc aaaatattga gaaccgagta tgggtgggat tcgttggcat
124801 caagaaacgt ttggtctttt tataatggca acgtgttgat taatgacact ttgccagatg
124861 aaatcagtcc tgaattatta tccaaatata aggaacaaat aatacaagga ttttactggg
124921 ctgtaaaaga ggggcctttg gcagaagaac caatttatgg tgtacagtat aaattgttat
124981 cgatctcagt accttccgac gtaaacattg acgttatgaa aagtcaaatt attccgctaa
125041 tgaaaaaagc ctgttacgtt ggcttactga cagcaatccc aattttattg gaacccatct
125101 atgaagttga catcacggtc cacgccccct tgctgccaat agtagaggaa cttatgaaga
125161 agagacgtgg aagcaggata tacaaaacaa taaaagtggc agggacacca ttgttggagg
125221 ttcgtggaca agttccggtt attgaatctg caggattcga gacagatttg agattatcta
125281 cgaatggtct tggtatgtgt cagctgtact tttggcacaa gatatggagg aaggttcctg
125341 gtgatgtttt ggataaagat gcgtttattc caaaattgaa acccgcacct atcaacagtt
125401 taagtcgtga tttcgtgatg aaaacaagaa ggcggaaggg tatttctaca ggtggattta
125461 tgtcaaatga tggtcctacg cttgaaaagt atataagcgc tgaattatac gctcaattaa
125521 gagaaaatgg cttagtaccg tgaaaatctt ggcgcataag aattaagcaa tatgtccaca
125581 atatttttat tcagcagaat ttacatatga cttcgtattt agtgatataa ctactcatcg
125641 ggactgaaaa ttttttattt ctgcctaaat acagatgaga tgagctttat agaattttac
125701 gctgttaaaa agttaaacgg taacaaagca cagttagttg aacaacggta tatagagaat
125761 ggctaaaggt ttcaagttga aggagttgct ttcgcatcaa aaggaaattg aaaaagctga
125821 aaagcttgaa aatgacctaa agaaaaagaa atcccaagaa ttgaagaaag aagaaccaac
125881 tatcgttaca gcttctaatt tgaaaaagct tgagaagaaa gaaaagaagg ccgatgttaa
125941 gaaggaagtt gctgcagata ctgaagaata tcaaagccaa gccctttcta aaaaagagaa
126001 aagaaagttg aaaaaagaat tgaaaaaaat gcaagaacag gacgctaccg aagctcaaaa
126061 gcatatgtct ggcgatgaag atgaatctgg cgacgataga gaggaagaag aagaagaaga
126121 agaagaagaa gaaggaagac tggatcttga gaaattggcc aaaagtgact ctgagtctga
126181 agatgattct gagtctgaaa atgattctga agaggatgag gatgtcgttg ctaaagaaga
126241 aagcgaggaa aaggaagagc aagaagaaga acaagacgtt ccattgtcag acgtggaatt
126301 tgattctgat gcagatgtcg ttccacatca taaactaacc gtcaacaaca caaaagcgat
126361 gaaacatgcc ttagaaaggg tacaattgcc atggaaaaaa cattcattcc aagagcacca
126421 aagcgttaca tcagaaacta atacggatga acatattaag gacatatacg atgatactga
126481 aagggaatta gcattttaca agcaatcact ggacgctgtt ttagtagcac gtgacgaatt
126541 gaaacgacta aaagtaccct tcaaaagacc attggattat tttgctgaaa tggtgaaaag
126601 tgatgaacat atggacaaga ttaagggtaa gttgattgaa gaagccagtg acaagaaggc
126661 acgtgaagaa gctagaagac aaaggcaatt gaagaaattt ggtaagcaag tccaaaacgc
126721 taccttacag aaacgtcaat tggagaaaag agaaacactg gaaaagatca aatctttgaa
126781 gaacaaaaga aagcacaacg agatcgatca ctccgagttc aacgtcggtg tagaggaaga
126841 agttgaagga aaaaggttcg atagaggcag gcctaacgga aagagagccg caaaaaacgc
126901 taagtatggc caaggaggca tgaagagatt caagaggaag aatgatgcta cctcttctgc
126961 tgatgtcagc ggcttttctt ccagaaaaat gaaggggaag accaatagac caggaaagag
127021 tagacgtgcc agaagattct aagccgttat gtcggcaaga acactgtata tatccagaac
127081 gtaaagtata tacaactatc tatcatctct ttgtacacta gtataaaata gaattaaatc
127141 caacgaagcc ctaaaaggct tttgtaaccc tgccaagatg acgggaaaat aaagggaaag
127201 accttatgtt tttgcccaaa aaccctagcg ccggcgctaa tattaatggc cggaatgaaa
127261 aggtcccgga actttgtgta tggcgttgcg ctcttcctgt gagtgggggg aaacagatta
127321 gataattgaa ttcaataaca acagtcaatg ggggacggag ggtcttatgt tccctttggg
127381 tcatcgggga cgcaagtaag aagatacgca atcagcaagc gctgttatta ctctaacgaa
127441 gaaatctttt cagcaaaacg gtccaaaaga acgaatgttt acgtcgcagc gacagcttcg
127501 acaaaatggg agtccgatgt catcatcacg ttcatcacaa cattcctctg gtacagcgtc
127561 gccgatatca gactctccag catcgaatcg cagctatgga agagatctac gaggcttaat
127621 gggaattgat atacctgcta acgaaccagc ttttaacagg gccaatagca gtgatacaat
127681 ctatttcagg cctaagaaga tttacaaaat ggaacatgag cacccatcac gatctacttt
127741 agtacaactg cagacaagat cgcagccgga cgatgtcgca agtagtcaag taaaccctga
127801 aggcggaacc gacgatctag agctgggcga tccgtgtggc aatcaatctt tatacactat
127861 aggggcggag tacgttccag atttagactt tacaaagcta gtgaatgagt ggcaaaagtc
127921 caccgaggat ttgtatgagt tcagaagcag tgccactccg caggtacaaa tcaaagacag
127981 tggaaaggga aactacgaac tttggagctc accggatgca atattgactc aaaacaaact
128041 tcgaagagat agtttttcgc aagagaacag tgattcgtta agtccagaag attctatttt
128101 atcaagaaat ttgcattcta aggtcaaacc catccctctg cccagaaaca gccagcaaat
128161 atttacaccc ctgtccaact tagaagcgga aaggagatcc tcatatacaa ctagtagcaa
128221 caacaatagc ataacacaga ataataaatt ctcttttgcg aagttaaagt attcacttcc
128281 aactcaaagt tctgcagttc ctgcgtcgtt cgattcaaat gcttcgtcac taaattttct
128341 tccgactact acattatcga ccttatcaga gctacaaata agccccaacg atatgatgga
128401 tttgattcag aagcttccca gaaatttttt gaacttgccg tatactcaaa ggaaaaaggt
128461 gattatcgag catgcaccat ctcatgacta caaggccatg atgtccctag ttaagaagtt
128521 tatgttaaca tcttctagaa gtaacttttc tctcgctggg tttgccaata atgcttcagt
128581 ttcgcaggcc acggctaatg atgataacat caatagtagg aacacgccca ataatagcaa
128641 tgacacctac gtaaatacgc gtccacttca aagatctagg cacggttcca ttgcatccca
128701 atttttaagt tctttttcac cttcgatgac gtcaatagct aaaatgaatt cgaacccatt
128761 gagtggaagc gcaggtggca gtgcgagacc agacgataag ggtatggaaa tactaggtca
128821 tcggttgggt aaaatcatag gtttcggcgc atgggggatc atacgggaat gctttgatat
128881 tgaaactggt gttggtagag tgataaaaat tgtgaagttc aaaggacacc aaaatatcaa
128941 gaaacatgtg ctgagagaag tagccatatg gaggactttg aagcataaca gaatactccc
129001 ccttttagat tggaagcttg atgacaacta tgcaatgtat tgtttaacgg aaagaattaa
129061 cgatggtacc ttatacgact tggtaatatc ttgggacgaa ttcaaacgtt cgaagatacc
129121 atttgcagag agatgcagat tgaccatttt tttaagctta caactattat ctgcattaaa
129181 gtacatgcat tccaaaacga ttgttcatgg tgacatcaaa ttagaaaact gtctgttaca
129241 aaaagaaggt aaaaaatcgg attggaaggt tttcctatgc gattttggaa tgagttgcca
129301 cttcgatgag aagcatgttt atcgtaacga tacttttgat gaaaacttga gtagtggcaa
129361 cagccataga aagagaaaaa gtattgaaca aactaatttg ataaagtatc ccacaaccaa
129421 ttttttacct gacgaccgaa ctaatgattt tgacgctagt gaaaacttaa aataccaatt
129481 tgaaaatcga aagcatcaac cgtttacacc aaaaggaatg gttagctcca gttcacattc
129541 attaaagcat ctcaatcaac catcctcttc ttcttcttct aatctatttc acaagccagc
129601 ctctcaacct caaccacagc atcggagtcc ctttcatggg aggcacaaga caaccgattt
129661 ttcaaacctg gaacccgaac cttctaaata tatcggatct ctgccttacg cttcgccaga
129721 acttctaaga tactcagatg caagacgttc aaaatcagtt gaaatgcata tttatgattc
129781 accagactcc tctcaatcgg aaattagcgc agcatcatca tcttcctcta atttatcttc
129841 tctatcatcc tctacaaagg cgtccgcagt cacgaattcc ggtgtaacta caagttcacc
129901 gtctggttca tcgactgatt ttccatgtat tgtttctcct ttaggaccag catccgatat
129961 ttgggccttg ggagtaatgc tatatacaat gttagtagga aaattaccct ttaatcatga
130021 gttcgaacct aggttacgct ctctgattaa agtaggcgaa tttgaccgat tttctttagc
130081 tcaggtctgt aaatttgaca ggaaaaaaaa tgaaggaacg attggtcaag gcttgtatga
130141 cacagtcatt ggatgtttga cgattgactt ggataagagg tggaaattga aaaggattga
130201 agaagtcctt caaaacgaaa tgaacctaag cgaggccatt cacgataata atggctcatg
130261 acttatgatt aatgatattg attgcattga aaaaatacat acattgtgct tacttttttt
130321 tctcccattt tataaattat aacgaacttc ataattacta ttacgaaata tgtaaataag
130381 tatttttatc gcatatttga tgcctctatc acttatttgg cgctattcat tgcgactcgt
130441 gcaacgtgcg aaaactcaga atattttttt gaacagcctt aaatcatgtt gctaaatgac
130501 ggatggaaga aaagggacct atagaagagt tcggataaat tgtgaagcgt ggatattggc
130561 atagcggatt tgtagaacgg tgtgtcgtca accctttgag atctggataa gccatatttt
130621 ctaacatcac aacatgatat ttctaaaatc tgtcatcaag gtaatcgaca attcaggtgc
130681 acaattagca gaatgtatta aagtaataag gaaagggtcc cccaagagtc ctgcaatggt
130741 tggagacaga atagtctgtg ttatacagaa agcaaagccc ttgactcaaa acattacggg
130801 gacagccaac accaaccgtg tcaaaaaagg tgatatttgt cacgcaattg tcgtaaggtc
130861 taaacagcgt aacatgtgca gaaaggatgg ctccaccgtt gcattcggag atactgcttg
130921 cgttttgatt aataaaaata ccggtgaacc tctggggaca agaattatgg ctaatgatgg
130981 ttgtgtagat agaacactga aagacaaggg atacaataag atatgctctt tggcaagtag
131041 ggtcatataa gaataaaagt acccccattt tccattcatt aacgttataa tcaagggact
131101 gtaaaccagc aaaagagctt tgtcgtcatt atttaattaa ccacctgtat atattgctta
131161 aattttaatg tatgacttta actttgaaaa cgcatgaacg tgctgctgac gttctactca
131221 ttggagttgt attctttttc ttgtcttatt ctataattgc atgccgtgaa tattgtatac
131281 aagatattta tgtggaatca tatattaggc agcaattcgt acttttcatc cactgcatat
131341 ctaaaagttt gccaacagaa atcctttttc ttggttccca ttgaaagatg cgatataatg
131401 cgatttttct atttgtggcc aactctgagt ttacgtgctt taattcttcg aataccctaa
131461 actggttttt acgctgcatt tccttgtaaa attcatcata agacatatct ttttctctcg
131521 aagctacttt ccaaagataa tgccccaata tcattgttat ataaacaacg ccacaactcc
131581 aacagtcaat cagtcttgga tcgtaatact ccccatcaac aaactcttct ggagctacgt
131641 aaggctctga tccaattata cccttttgag catgaaccct cctttcccaa gcggtttgaa
131701 atacagaact tgtaccgaag tcacatattt tcaatagacc atgcggataa aagagaatat
131761 tttcaggttt taaatcacaa tgagcgatac catgatcatg catgaactta acaccatgaa
131821 gcagttgctt catgaaacaa tcggcttcta acggatgtaa tcggcccttt aatttcgact
131881 taccgaccag cataccataa aggtcaccag cagggcaaaa ttccattact tcaataaacg
131941 aagaactgtc ttctagaata tcaaatacgt ttagaatatt gggggctggt tttttaccat
132001 ttttgtggta gtggctcaag gaatgcccaa taataaactc agaggtgatc tttgtacaga
132061 acttctctaa atcactgtct ggtttgggtt tcaattcttt cacagcatag tatatgtatt
132121 tgctatcatg atatgtttca aatggggggg agtccttttc attccgtagt ctggcacaca
132181 gcttaacttc accgtaagct ccagcgccaa cgagaccaac aggatggcca taattatctt
132241 gaaaagtagg tgcttgctcg ccgatacact cagccggttt tagatttttt tcttgcaaat
132301 aattttgtaa acttttatga attctgcttg ataatgaatt aatcaacttc aactcatcac
132361 tgcccaatga tgcgtcggga ttcactattt ttagataatc ttcccttcct tgcgtgggcg
132421 agctgcggtt gctatcgtta ggactttgac cggttctttt ctcatggttt gtctgagatt
132481 tttctacgtt tggcagaaga gataaagcgt tttcaatatc gcattcattt ttatgatgtt
132541 tgaatagacc agaaagagta atacctaatc ttggtctaga taatgatccc tgtcgatgtg
132601 ccggtaagga gttacctttc tctaatttcg caattacccc tgataacttt atattatgtt
132661 catgacttcc gtcttcgtaa actttgaagc cattttgctc aattatacat tgcacatctg
132721 ctcctgcaaa tcgaggcaag ctctccaaac tttcttcatc tggatgtgac ctcctggtgt
132781 ataacctttc attatagaat tgcttggagg ggagaggatt tggatatgat gttgctctgc
132841 gtaaagcctt cttattgtag tcatctatgt aattatacgg cgcccggtct ttacttttca
132901 gtatatcttt gttcgagcca cgataaggtg tgaggtcatt gtctgaatca tctagtaaag
132961 aatccatagc ccattgactg tctgatgaac ttgtcgttcc atttgaactg tcacatgacg
133021 aaacagatga acttcttgaa cgtggacgcc gtatgccatg aaaagtatga gaagcagatc
133081 ttttgtattc tggtaaactg ttaacaattt cctgttcttc cccagatata gagcgatgtc
133141 tggtaggact attactagca ccacttcctg tctgtctaaa tggatgtgac aggcccgggg
133201 tgcaacactt caatgtataa ctacgctggc gtattggaga attttttgga tctaaaattt
133261 gtgcggatac ggttgatcgt cttggtggct cagagcttct cttgggtgag gtagaagacg
133321 atcgataagg aattcgggtg acattaatag gacttgaatc tcttgaacga ggcggcctga
133381 aaaggttttt aaaggactca gaaaatgacc ttactcttct tgtcacaggt tgttgccgct
133441 tcttctcctc ctgcattacc attgatgctg tcaatgtttt tgagtccatc atgcaattaa
133501 actagctagt tgaagtgaaa atgaaatttc cttattttcc acaagaaata cgcggagggc
133561 aaaaaaaggg acccaagggc tgacaatatt cagcacaatc ctacttattg tactctaaat
133621 tatatactta tatgccccat aagtgagttt tgaatttaca tatttccatg aagggcaatg
133681 ttttttgata tatacatgaa caaacttatc gagagaaagc ttatataata ctttcttgcg
133741 gtccaactct tatgatctca ttttcaggaa gaggaacgtg ctctattttg tcaagtaagt
133801 ctttcattat atcttcatgc attttattac gcatatcaat agtctctaca acggagcctt
133861 catgagataa aatctccagt ttgcatggaa cgcttttttg cttgtcttcg ttctttatcc
133921 ttatcacgtc aaacttcatt cttggattat agaactgcaa agtgggtagg tagttatgcc
133981 aaaaaactct ggcacccata tgtccattgt ggtttttcgt ttgaaaagtc aatctaagac
134041 ctgagtattt tttaggatcg actagaatct gcggtagtct ggtagtggcg ctaattttat
134101 tcaaaaattt taactgttgt gcaaccttag acatcttctt attgtagcag gctcacttat
134161 gttatactgt tcttctatta atgagtttta tggccgattc ttacagatat cctgttttcc
134221 ctgggtgaaa agtcctagat cactttgaac gtcccagtct tctgaggacg caaatgtagt
134281 cacaatatgg cgtatatgaa tgctccttta tttatctgta tacacctcta ttgaatagac
134341 gtacgtagat atatacatgt acatatatgc atgtgtcact tttttatcat ggccctgtta
134401 gactcaccaa gaatctataa ccaggtttgt ttgtgctttt tcttgttctt gtttttactt
134461 ttattgattt tttttttttt tcaattacaa ttatcccact gaacctcctt aaaattcttt
134521 cattaaatcc atatatggat cctccccttg aattccatag ttgaattcct cttcagggta
134581 tctgtcaaat tgagaagtgt caccttggcc ctgttggatt ggtggttcgt acggcgtttc
134641 tatgtatctt gctaacaatt tctcccatat cacttcgtta aaccacggat ggttcttgac
134701 atcttcactt ccattttgta agttacccaa cctttcactt aagtctctgg taattagctt
134761 cttcaataag tcctgcgcgt ctggatggaa aaatggtggg aacttcaatt cggcgttcag
134821 tatattttcg taagttttca tggtgttcga attgtaaaat ggagtgtatc cggcaagcat
134881 ttcatagatt agcacaccaa aactccacca atccactgat ttattatacg gttttgtact
134941 gaccacttcc ggcgctatgt aatctggtgt gccacataat gtgtatgtga catcgggaac
135001 gtattttgcg aagccaaagt cggttatctt gatatggccg tttttatcta gaaggatatt
135061 ttctggtttc aagtctctat atattatatc cttactgtgc aaatattcca acgctaagca
135121 tacctctgcg gcataaaatt tggctactgg gttgggaaat ctttgagatt tacgtagtaa
135181 agaaaataat tcaccacctt caatgtagtc cattaccatg aaaacttgct gagaatcttg
135241 gaacgttccc cacattcgaa tgatgaatgg atgtgaaaca attgaaagca ttcggcgttc
135301 gtcattggtg tgttcaacct gcttcagctt cactatagtg tgctttttca atgtcttcaa
135361 agcgtaaaac ctcccattgt gattggaacg aattaggtga actctcccaa atgagccagt
135421 tcccaaagtt cttaaaatct gaaagtcact tagggaatac tttcctgagg tatctctata
135481 ttgtagcatt ggttttttaa ccaaacaaat acctgcagac gcttcttctt tcaactttcc
135541 gctgtttctt ccatttatct ccacgggtgt gttggaagaa cattcctcat gcaccgaatg
135601 tgcgtttaca ggaatgtctt gtccaacgtt atctggagtt gtttctgtct tggcagtaat
135661 gcttaatttc ctgatttcat tgttgttcat cggatcaaca tacattttgt gcaggctcgc
135721 tctttccttg tacaaccacc gatatacaat atgattaatg tattattcaa taatatacgt
135781 gaaactttct tattgcttaa agagtgatcg cctataaatt ttctccgacg actgcacaaa
135841 gtgtctcgta tgtccactcg agtttcttac cgatagaagt aataaagcag acaaaacttt
135901 taagatcagc tggtaaaaag tgtcttttct ttccatattc tcattgaaca caactttatt
135961 tttcaatggc atcgaagaaa tcccgtagct gaagcaacgg aaaaaaaata ccggaaactg
136021 cataatgagg ctattcacta aaaagaaagt ggttcaccag tatgcgtcgg aaacgtcata
136081 taaatctata tatgtatatg tacatatata tatatatata tatatattag tgagtatttt
136141 aatgtatatc aagttttgat aaagattgca acttggcttg aaataaacgc atttttgcgc
136201 accagagagt atctgaaacg ttgacgcaat tttgcaaaaa tgcatagtcg cttttcttca
136261 gaccttccta aatcactcgt acctggaacg actttttgaa gaatgaagtc gttgtcctct
136321 tgaaaaaaat agtaaatgat acggttgatc ggccggtggc caccgtcgtg acaaacctag
136381 gaactcaatt aggaccatgg catataagta tatgtggtcc aagcttcgct gtgtaggccg
136441 taattttgcc ggcatttact atattgttga cgaataagtg atagatttgc catatttatc
136501 cctcctaaag ctcggtaaag ggaactatct gagatggata gcttgaagaa aaaaaaatac
136561 ttgctgatgg acctccatgt acaacttttg aaatagttgg gacattaaat ggagtatggt
136621 atgcggttat aaaagtaact ccccgaagct cacttagaga agaaattgtc ttgctaaggt
136681 aatagatctt ggaaagttta aacaatcgtc aattttttcg ctccttaagc aattgatgtt
136741 gttgcgttat tttctggcaa cgacgactgg caggtcatag agacctaccc aaaccaataa
136801 agtctcaaaa attccacttt tcatcaaaaa ctaaggaatt agtcttcctg cgggcagtga
136861 atgcttttat cgttatgact ttagtgcaaa ttgtagatat ttcgaatgct ttttgcattt
136921 aaaaatgaaa atctatggcc atttcttgtt ttaaactcat tgaactttca aggtaaattc
136981 acgagcaata tattggcatt gtcaccacgc tacaattcgg taagtttctc gattcaaact
137041 agtaaataca actattggaa gggcacccgg tgctaaggcg agaaaactgc tgattgtgta
137101 cattattagg tgtgattagg aaaaatgaac gcgaatagta atttatttca aagatgtgct
137161 tttttttttc gctgtatagc tgttacaaga cctgctatta aaaaattcac tagcaaaaat
137221 tgctagtata aagctattga agtacttgat gagtttaaat ttttccttgc cgccatttct
137281 ttcgacagga gtactttatc gaaaagataa aggcaaaagt tatatatttt taaaaacgct
137341 ccaaatggat agtacttaga caaagctcaa gtaatgtatt ccttaatgtg tcaaaattgg
137401 ccactatggt tgtgattata tttgaattaa actcgtgaga gtgttgaagt attcaattca
137461 gtatcattaa atgcctcttt tgtttgttag ttcgaaaatg agaaattgag acataaaata
137521 ctgtcttcaa acaatcggaa aataacacat tgatttacca tcacagaaga tttttacctc
137581 agtacagtgt cggtggccaa cgtgtaaaga cttcttatat atccgaattt ttttcttttc
137641 agatttattt tttagaatga attccaagac cttgattccc ttattctttt ctccgcaata
137701 gttgcctact aactgggcat aacttaaaag aagcagataa taagataacc ggaaaaaaca
137761 ggaacatttt ctttgataca tttctactaa cttgaataag gttataggtt agtatttccc
137821 cttgattttg cctcctttga ggcatttata gaattattca acaggtagat tgcccctgtc
137881 tttcttaata tacatatagg aaaatatata catagcggtg ggtatgtgaa tctattgtgt
137941 ttttttggtt ttatcctgta tgatgacatt ttttagcaac acatgaccga gtacttccaa
138001 aataagcatg aacaaagatg ataggatcgc caaacaatag ttggaaatgg ttatgccaat
138061 atccaaccac gacccctccg ttcttaaaag gtagaaaaaa ttcaacgaca gaatatcact
138121 catggaaata attaatgatg agattgtgta gtccttgaag ttaagtttta aattcagtat
138181 acctaggcat gtggacaata gcccgtaggg aattatcaat ttcaacatca ataatgcgcc
138241 catcaggaaa ggatcaaaaa ttggcaacaa tctacaaaca gactccaatg aaaatgaaga
138301 gattgaagcg acgttaccag ttccaaagaa tgcgacttga agtaaaaaga acccgattac
138361 tgaaactctt agcacttgta accaattttc atctttttgg gtcttcattt ctttgatttt
138421 gttctcaatt tcaatccatt gtaccatgta actagtgaac aagaagtaga aaagggattc
138481 gaatgatata gtcaaaatga taaaggatgg tgcgaaggtt aaataaatga tcaataatct
138541 cactttgtaa tcattgttgg gcttcctata atgtaaaatt ggcattacaa aaagagatac
138601 aaaaaaaatt atccatccag cgacctgtga ctctcttggt aacccttgtc ttagctgtaa
138661 agagataact gaacgatgag taaccgccaa catggcagcc accaaggaaa tttgaatggc
138721 aaatatagca cgcgtgtagg aatttatcct ggaatgtatt ttgtaaagag cataaaaggc
138781 actgagaatg attaataacc ctgctagatg tatctggttc aagtcctcaa ttttaacagc
138841 gtcaaataag gtaaatgtag ataaaagaac actagttatg atccacaata tattcacgga
138901 tagctctctc accccacaaa taaacgggta aaacgccaat atatttgtaa ttagcgtaaa
138961 cgtccatcta tggaaaaatc catatacaat tccctcataa actgatataa tagagattgt
139021 tattaaaact cttttccaag gagaggtacc tttgaagaat tccttgatac ctgaacgtag
139081 tacggatcta tttgtaaaaa tatagctcca aaagtataat gggaaaagaa ggtacatgta
139141 aaaattgaac ggagaatgtt ggtagaacaa aatccaattt agtaaaattc ctatggaacc
139201 aaatactgca tggcttaatg gtgacgcttt ttggtcatca attacattct ctaatatgaa
139261 tgatttcaaa aatattataa aagaaaaaaa gatccaccca acaaacccaa atgtaacaat
139321 agttctaatg aatctccaat tataggttgt caaataatgt aaaccttcca atgttatctg
139381 cattaattcc tctgtaaggg tgattgcttc ttgttccaaa tagttttctc cttcagatat
139441 acgctgaatt aaggtttcta tctcttctaa gtaatgtgaa tgagactttt caacaaactt
139501 gaagtattcc ttataaaaaa attgagagtc tattacctca tcttgcttga ctaagtactg
139561 ctctaaaatg cttcttgcgt tgttgtacaa tgcggcaagc ttgtcacttt cttttccatc
139621 gatatatgct attggtaact caccaactga atttttagga tagttcacac caatcaagta
139681 tgacattaaa gaagcaatat ctgcttgctt gacatcattt cttttaatgc tcgaaagctc
139741 ccaattttca gtatagttgt cggataccgg aaaaggatta tgtactggtt tattcaaacc
139801 cgcaccccaa gcaacaagag gggtccttgt gttgttagga tgaccgtcac catgtgatcc
139861 aaatgcactc ataccatgat ctgctgtaaa aataaatgcg gttttgtcgt ccgcaaaaaa
139921 cttgttgact ttgtctataa ggatagggat ttgatcatca atatatttga cattgtcata
139981 atactcggca gaatatggtc tataagaatg tccggcagta tcgcaaccta gtagatgtag
140041 aaagaataca ttaccgtctt gcctaatttc ataatccaat gttgagttca gtgtggaatt
140101 gtggaataat tgatccaagt gtctaaagac aaaagcatcc agctcgatgg aagattgcgt
140161 aaaatcctcg aaagtatgat catacatcca agtgtcaact ttatttgggt cagaagcgcc
140221 atctttgaac ataggtaaaa tgtcaggtga accgaatgaa taagtatgag tagattggtt
140281 gaaaaaacta tcgaaattga cagggtttga cttccaacct tttgtgacgg cactaacatc
140341 ttcgtaaaac ccagcaatca tagcaacatg accaggacgg gattcagttg gcattctggt
140401 atgtgatata ccgtaggtgg cattattcat taccaaagat ctaataaaag gtgccagaaa
140461 ttctgttttt ccggatactg gatgagtgac tttatcaaaa gtggtatctg cacgtaaacc
140521 atcaccgaca atcaaaaaca atctctttgc aggaggggtt ggagtacttt gatatgggct
140581 cataccatga acgagcggtg aaatgaaata gatatcaaaa atagaccata ggtaaaataa
140641 atgaaataag acaccaacag ccagaagcgt cgttctggtt ttgttccaca ttttttacag
140701 atttcagttg tatgagtcct aaggctcttc aatgctttgg tcgaagatgg gttgttgaat
140761 atatagtaaa gaacggttct ttttaccttt aaggtttttt tttcgcgttt aatgacagcg
140821 atgcaaaaag aatacacata ttatttacgt ggcatcaaca tatacatatt caacgattaa
140881 catcctgtag tttaggacga aaagacacat atgaaataca tatctatgaa aagtactgca
140941 ccataatgat tcaacaaaat aaaatgagta acattaacat cacgctagta ctgctagatt
141001 aaaaataata atgaaaactc cgatacgggg agtcgaaccc cggtctccac ggtgaaagcg
141061 tgatgtgata gccgttacac tatatcggat tacaaaggat agaaaattga aacgtaatgg
141121 aattactcat gtaaatatta aagaactctt ttcatttaca tggataattg gtgaatgttg
141181 tggggaatgt tggatttcat tgctgttaaa ggctataata ttatgtgtac agaatacacc
141241 gtgtgtgata atatactagt aacacgtata ctactaaatg gatgataata tgcatgtcaa
141301 ttttcttaaa ttttgactga gatagtgacg aatatatggc attataagat gacaacaatt
141361 tgtttccttc tcaaatgaga aagggctcca cggtacacaa agtaatgtct gagaaatatt
141421 ctgtcccagg aatagttgaa gttgcatccg atttcaatcc cgtgaagtct tggtactatc
141481 aaattcgttg gttttttttc tgggaaaact ctatcaaagt ataaggtgcg cttttaacgt
141541 aatttataat gattttttag aaataataat gtatatagta taaaaaaata aacaaacttt
141601 aaaaaaaaga gtgaagaact gtaaagctca tttcataggt ttcaaaagaa agctttatga
141661 aatgaagaga cgaattaaga agaaaaaaat gaaccgaccc aaattatgcc ctttggagac
141721 agaaatgact aatgtacaga atatgctacg atgactttat gttttcatgc gactatgaga
141781 ggtaaactta tgattaacag ttgagcaaat cgatagcttg taggtggact gcattacatt
141841 gagttccaat gtgctcatcg tataagttgt agaagtttcc tgacaaacat tggtaaaaag
141901 tatcctggtc accgatggcc aagttacctt ctggggtgat ggaccaacca gcagcataga
141961 tagcaccagc ttgtggtgga ggaccatcga attggaattg tctgttggca acgatagaac
142021 caattctacc tttaccgtca gtcaggatac caccctttaa gttcatttct aaagtgccac
142081 tgcttttaca tgtttcagca gttactgggt cagtgccatt agtaattgga gctggagctg
142141 gagatggtat aatggttgca gaagttaaag ttgtggcttg gatttggcca tcagtgattt
142201 gggagactgg agcaacagta gtattggtgg tggcttggat ttgaccgtca ccaatttgag
142261 aaacagcagc agcagtggtt ttagtagtgg cttggatttg accgtcacca atttgagaga
142321 cagctgcagc agttgttttg gtagtggctt ggatttgacc gtcaccaatt tgagagacag
142381 cagcagcttt ggttttagta gtggcttgaa tttgaccgtc accaatttgg gagacggctg
142441 cagcggtagt cttagctgag gtagtcttgg tggtggcttg gatttggccg tcaccaattt
142501 gagagacagc agcagctttg gttttagtag tggcttggat ttgaccgtca ccaatttgag
142561 aaacagcagc agcagtggtt ttggtagtgg cttggatttg accgtcacca atttgagaga
142621 tagcagcggc tctcttagcc ttggaggaag cagtagtggc aattggttca acagcaatac
142681 cgaaagtaga agagtaatca gttataccac ccttgtaagt agctgatgga gttaaagtgg
142741 accacgggtc ctttggagca taggcagcta aagatgtagc aactaaggcg gaggcaacta
142801 atgatttttt gtattgcatt ttctagaata tactattagg ggagttttgt agtttgtttt
142861 tttttaatac cagtgtatta acttttgttt tcttgatgat attattctta tacagtaata
142921 gagaagatag gacaactatg cataaagtag taaagatctt gctccttttt atatgtgaga
142981 attgtagcat tacgatcttc ttattgaaag aataattagt ataccagcgt tctaatattt
143041 gggcaggaga gattgactgg acacagtcta aaccctttca gatacatggg ctaaatgatg
143101 gtccatcgta ttattaaagc aagtaatcga gctccaagaa ggatttacgt ccgccatctc
143161 aatttctttt attagcgttg cttctataat tggcaggaca taaaaaggct gctaataata
143221 aatgatgata taattaagag caagctggcc gatctctcca tttttatgcg ctccaagcca
143281 cgtcattttc cgatgacagg aatgctttgc atatttcata tgagatatac attgactcct
143341 tttcgaccaa ccgtttcatt aaaggggcag cagctgtcaa aaaagtagcc gaaaaaggcg
143401 tctggcttcg aggaattatt acctaaatag gaaaggcaga atatattaga aaaaaaagaa
143461 aaaccaaatg agaaaagtgc tggtgctaaa taaaacatta ttgaggggcc aagaggggac
143521 aaaagaagat ataactagat cattaagttt tcgctctagt aacaggaaca aagattgtga
143581 gatacactgt tatgctaaga gacggtgcga tattctgtac gaaaattatt taactattaa
143641 ctaaatgtat accacttcac gtgccaccga gtaggtttct aaaatgtgca accattttag
143701 gtatgtgcgc agctctttat tctaaacggg agtcactaca ttactattat cgtgtttttg
143761 cccatgtact ttcttataat cttaagacaa caacgggatg ataggcgcat tcggactttc
143821 attgatgcaa atgtgtgaaa aatgcatcca aaagacaact tttgtacaga atacaattgc
143881 aaaaatactt tacgggcata gatcggtaag gtcaccggga agctagcgta agagacctta
143941 ttcggaaccg agcaaccatt tccgaatgta gtagtagttg aaggagtaaa tcgaccttat
144001 tgtacactac ttcctttaaa tttgatttct ggccccgcgc aatttcttgg cggttaagct
144061 gtatttttac ctcatcggga aaagttattg caagttaaag gggatcaaac gattagcaaa
144121 ctaattatag atcaaaggcc gagggctttc taaatttggc atatttcgcc gtcgactgaa
144181 atagaaggga taaatcatgc atctccagga ttatccctac tccattcatt acaacatgcg
144241 ccaaatcaag cctatataag attctcgtca tttagcatgc tctattgatt tgtgtcttgt
144301 tttgtctaac actgaaactg taacctaaga tttctttaga taattattac atttacatca
144361 ataagaaatc tcataaaaca agtactgttt ataagtaaaa atgcaatata aaaagccatt
144421 agtcgtctcc gctttagctg ctacatcttt agctgcctat gctccaaagg acccgtggtc
144481 cactttaact ccatcagcta cttacaaggg tggtataaca gattactctt cgagtttcgg
144541 tattgctatt gaagccgtgg ctaccagtgc ttcctccgtc gcctcatcta aagcaaagag
144601 agccgcctct cagataggtg atggtcaagt acaggctgcc actactactg ctgctgtttc
144661 taagaaatcc accgctgctg ctgtttctca aataactgac ggtcaagttc aagctgctaa
144721 gtctactgcc gctgctgttt cccaaataac tgacggtcaa gttcaagctg ctaagtctac
144781 tgccgctgcc gtttctcaaa taactgacgg tcaagttcaa gctgctaagt ctactgccgc
144841 tgccgtttct caaataactg atggtcaagt tcaagctgcc aagtctactg ctgccgctgc
144901 ctctcagatt tctgacggcc aagttcaggc cactacctct actaaggctg ctgcatccca
144961 aattacagat gggcagatac aagcatctaa aactaccagt ggcgctagtc aagtaagtga
145021 tggccaagtc caggctactg ctgaagtgaa agacgctaac gatccagtcg atgttgtttc
145081 ctgtaataac aatagtacct tgtcaatgag tttaagcaag ggtatcttaa ccgataggaa
145141 gggtagaatt ggctctatcg ttgccaacag acagttccaa ttcgatggtc ctccaccaca
145201 agctggtgct atctatgctg ctggttggtc catcacccca gaaggtaact tagctcttgg
145261 tgaccaggat actttttacc aatgtttgtc tggtgacttc tataacttgt atgataagca
145321 cattggttct cagtgccatg aagtttattt gcaagctata gatttaattg actgttgaac
145381 gatgcatcga tcaatcggag tcgtcctcct ttaacttcac gaattagttg ccactctcat
145441 tccccacaca taaacttgtt ttatggcatc cttttcattt agcatgtctt tatttccaaa
145501 cctttcctcg ttctttgcat tcatttagcg tttgctcgag aaagcatcac gttttcacac
145561 attatcgttc gtcgctataa taaaaatagt tatagaattt actcagattt acatgtcgta
145621 cctttttaat tgtaaaaaaa aaaattttat gatacataat tacctaaata taattcagaa
145681 tcaaacatac ttatagctat ttgtatgcta ttaggtggtc ctgctataaa aatatcgttt
145741 ataatacttt atattttatc tttcaactta gtcgcaattg cagaagcttt ccctgagaaa
145801 aaatttgtga agctagctgc gatagcaaag gagcgcttaa ggtatagaaa agcactcagc
145861 tggaatgcca aaagatagtt tagcaactga ccaaggaaaa agcttgtagg tagacttaac
145921 ttcattgttc tctaatcctt tcgtcgtgta tattgtaaaa actgctgaac gagtattgat
145981 aaaagatatc ttggccacta aggggcagat ccccttctgg tgtgatagac aaccccagga
146041 gcatagataa caccaacttg tggtggaggg tcatcgaatt ggaattgtct gttggcaaca
146101 gtagaacaga tgctgccctt gctatctgtc aaaatgccgc tcttcaaagt tactttcaaa
146161 gcgctgtcac tgctacgaca gctttttttt tagaaacagc agcaatgcct tgacatgtaa
146221 cgtaagaaaa gaaaaaagag atggcagaag aaatactaag cgataacggc aatgtagagg
146281 tgcttttttt atcggaataa atagagaagt cagtaacagt gattgctgtg gctccctctt
146341 taatcgtatc tatgtaggtt ccgattaaag tggtcgtgat tcagtatttt ttttactaat
146401 caaagtacat gcactgtttt ttgtggggat agcaatgatt tcaatttggc cgtcaacgat
146461 ctaagaaaaa acgtctctct taaccgtggt agatcctgtt gtaattgttt ggacagtgat
146521 accgaagaag gaagtaaatt cagtagcgcc gcatgaggta gtagcagaag gagttaaggt
146581 tgaccatggc tcacttggca tatactgttg ggcagaaaca gtatagtgaa actgttatca
146641 aaccaatata tttgggctac atggctttcc tttcccgaaa aagacaccat ttagtaatta
146701 tgttgtactt ttactctctg aacttctgtg aatataaaaa atatactaaa taaaaggatg
146761 caacttcctt aaagagggca agatagcgac ataaagtgga aaagtgttag caacattgcg
146821 caggcatcga ttaatatatg catatatact ttttacgtag tctacgttaa attgtcaata
146881 gatcaagcag aatcggtagc tctgttaagc gattaagccc agtggctttt tgtcgcaccg
146941 tttaggttcg cgttagcaag atggaaaaaa aagaacgcga atcatgtatt gacgtatgac
147001 gtattaggca atttacaaga ttaaacttaa atttgcgacg gagttttgaa gtagaacgaa
147061 caccttactc atccgcaaca ggaaattttc acgcagaacg tgcctaagaa aaaaaaatca
147121 tatgcgttta caggcacaaa tgaagaaaat gaccggatat ggatataagc ttatggaaga
147181 aattgctcct attgagttaa gaatatgcga gcgagacctg cataaggcta attataactc
147241 ttcaacccaa atttgtcttt ctcttcacac ccatctctta tagtcccata tattcatatg
147301 aaagttcaat gcttagactc agtgtgtact tatgatgtcg ttgaaggcta tttggtctac
147361 tgaaaatcct acctcgtacg aataccctta tagtattatt taaatatggg gttactattc
147421 gcattcgtta gagtggtggg aaattgatat cttgtttggg agttgcgaaa caaaagagga
147481 gaagatatgc gcgctatgtt tttcttaaaa gaatgcctac tgcctatgaa atgaatatac
147541 taaacgtaaa agtgtagata atagaaacaa agattaaggt cgcttactgt aaaaaacgtc
147601 ttcattttaa ttcaacgaaa taaaagaaat cacgtggagt gtagcaccgc caaagagcta
147661 ttttttatgt cttctagttg aggcctattt ccattctgcg acgaaagtgt gcttctctca
147721 cttgggctaa tccatttttc aacaaaatca gcaacgtctt cgacttcgca gctactagaa
147781 gaactgttaa taccattata aatgttctgt aactgtaaga agtccgtcat gaagcatatt
147841 cttccactcc gtttgtctga aaatattgaa tccgaatatg gctgtactat ctggctagat
147901 cccgtcggcc gtgggcttat taaactcttt aataacgata ttattgttgg gctcgatctt
147961 tgcggggtgt ctacaatgaa aagtctatgt tctggaatat tattcttgat tgtcatcaat
148021 atctcaatta atttagtggg gatataaagt tctttaccag gacttacatg ggatcgatca
148081 ttgaacattt gttctaatgc aagttcacat gagtagtcaa tggcgctatc aaagctcttg
148141 gatttttgtc cattcttatt gatatccaca aagcactgtt gccacccttt gtcatctgaa
148201 gagtacctta ctaaatcgtg ggttgtgtat tttataacat cattaagcat caaaatttgg
148261 attggatcct ctatgtgaaa ttttttctgt aaaaaatatg gggaaaccgg ataatcttgt
148321 accaaactga ctgatccagg tattccgtct aagagcttcg aaggtatttt gtcacacttg
148381 tatagaggta ccatgaaata ttttattttc tggaacatgt tatcagataa agtagacttg
148441 agatatgaca ttaaattttt gcaaatctga attgcttggg gtaaatccgt gtaaatattc
148501 acaatgttaa gatcgtaata aggatagtca tttaatttgt aattaaccag tagccatttg
148561 gcaaggcatt tgctaaattg tggctcacag tcaagaatgt tatcaaatga aaagggttct
148621 tcttttgcgg ttgtagttac aggcttcctt tgcgtaaaaa aattttctct tttcattatg
148681 tttgggaaat tttgccactc tatgtaatct ttcaaagaaa ttctcgcagt ttggcctctt
148741 cttatcccat ttgtagagag taattgctcg aaagtaaaca gtgggtaatc agatttcaga
148801 tgaacttgaa ttctcaaggg gtgtaatctt ttcatcattc aatcccgcca aaagcacctt
148861 taaatgatat caactttttt gtgaaaatat tagtaagcta tttaaaacgg gaaagaaaac
148921 ttgagagagg actgacgagg gaatcatgtt tatattcgga tcatcgcgaa tctacgcaat
148981 ggtgtatcct actttctcac attttggttt ttcccgcttt cggaaggaac tgcaaaaccg
149041 ccgagaggac tttctctttt tgcaatattt gaagtatata ccaataatta agaaggtgaa
149101 caggcatttt acatattcat tatagatagt gtatgtgcgc atctattagt tgtggttttc
149161 tgctacaaaa atttatcgtc taaataattc aagttctttt tctaggtcga agaaaaaatc
149221 gctgtcatcc tcatttgtat tttggtttgt accatcattg acatttatat cgtgacctgg
149281 gggagacgat gaaactgggc tcatttttgt tatatttggc tcagtaggtc cgttcagtag
149341 ttcactattt tcatgcttag tatcttgttt gaaggtgttt tccttttagt taacaccctg
149401 aaatgaatta gagcttattc ccataaggtt ttgatatggc tgggttgtag ttagtgatgg
149461 aagttggctt acataggaaa attcaggact ataactgggt aaaactttcc tagaaggatg
149521 gacctgtaca acttcttgag gaatggcatc ctctaaagat agtgatgatg atggggaatc
149581 accgctaata ggatgttttc taacaacttt cctgaaatca aatacttcct ttataacttc
149641 gtttcctaat tccgccatac tttcgatatg ctcgaattcg aatctaaagg tcttttgaca
149701 tgagaattcc tcatctatat catgccacat tgacaaatat ggatgctcta gtgcatcctc
149761 tacagtaatc ctttttttag gatcaaattc tagcattttc tttagcaatt caagcgcttc
149821 tggattagca ccaggtagta tgctttcaaa cgatcttccc gggatattac cgaactgaaa
149881 gatataatta tacacctttt gagaggcaat ttcctgcaat gtttcctcag gtggtgttcc
149941 aagtatttgt agaatatgat tcaaatgatc tacataatcc ttcccttcaa acattggttt
150001 cctaccaagt agttcggcca agatacagcc tgttgaccaa atatcgacag cttttgtgca
150061 ttcttgataa ttcagcaaaa tttctggtgc tttataccat atcgaggtta tataaccctt
150121 aatgaagccg tcgttaacct tgtggttttc tgaataacta cacgatagcc caaaattaca
150181 aatttttagt tggcaatcac tattaacaag taagtttttt ggtttcaggt cacaatgtaa
150241 aacattagca gaatgtatgt atttcagagc acacagtatc tgatatatga agctttgaaa
150301 gtgtgcgtct tccaggcgtt gttcggacct tataatttga gaaaggtcac attccattag
150361 ttcttcatat aaataaacgc catttagtgc cccatttggg taaaatacta tatcagtatc
150421 gaagagccac actatatttg ggtgccctct taaatgtctt agtagtttca attcacgaag
150481 agttctcttg caagatagtt tattgccaaa cgcgtttggt atttttctga tagccacgtg
150541 agtttcctcg ttcgattctg tgtaagttga agaacaaata aggctgtgtg agccccgacc
150601 aatcttacct gtcaaatgaa aatgtttatt taggataaaa tcttggccga atgcacggaa
150661 aatacacctc tcggtgtcag tcgccattta attgtgaatc tttcttcgat atcaaactat
150721 tccaggccga attaatctgg cggtaagtca cctttagtta tccttccatt ttgtcccttt
150781 tcatccagtc tcaaacgaca attaggactt acattaaata ggctttttgc ctagtataac
150841 atcataaaag taccttcttt tgtttcttcc aaaaaaagac agtaaccatc tgaaaagaac
150901 gtcattgtcg aaaattacaa agtttgtggc agcgcttttt actgcagcaa gtcaattgct
150961 ttcatggcat tttcaatcaa aatacgagtt cttactaatt cctacggtgc ttcctgcatt
151021 gattgatcgc gagttactat ttttaactcg aatgggtctg cgcgtgtttc tccggtgttg
151081 ttcaaaataa tctgtttgct gcgtttaata actacaacag ttaacggaaa cagtgaaatt
151141 tattggggac tttcaagtaa cgaataatca tgctggtaga aatatttcta tttttataat
151201 taacaaatct tttaatgacg tcttgtgggc tgaaaactac ggcgtttatt ttttagatag
151261 gttattcctt cgttggattg agtaagaaaa tgtcgatact gtgttacgtt tgcaaggaaa
151321 agatttagtt gcgattagcc attcattctt gtggaaactt ctttaaaaag ggatggcgat
151381 ggagtactta tgtccaatta tgaagtcaaa tttattttca aaccgttaca cgtagattat
151441 tttcctgcag tggtaagtat ctttgaagtg ttgaaagttt tttggcacat atttttttgc
151501 ggatgtgggc ctgagtttcc tgttagaaac aaagatatgc ttaaaactaa ataacattgg
151561 aaattagggc atagtcttca atgttatact taaacatcac agcaggagat tgagatgatt
151621 gaaagaatgg tgcaagaaat gattcattaa cattcttcca agttttgcaa tatttgcaag
151681 tattactatc agactttagt tgaagtgact atgctattac caaatttcac tggagccaga
151741 aaaataaaga tcacttagag acaaagaaaa gtaacatctt caacataagc cggagctcaa
151801 aagtaggaaa tcggataaga aacttgattc tgttatttca agtgattttt tgctgtatcg
151861 cccacgttct tgttgtagat gttttgtaga tgtgggaccg aaagtaagtg aacagtgaag
151921 taaacagaat aggattctaa aaaagagctt ataaactgtt ctttaaaatt ttttctttcg
151981 tgaatgtcct cgagctatct caaagaaaac gaaatcttca ttcaacttaa gtgtaggtat
152041 tatttgctgt ttcatcaaat gcggcaccaa agtggaagta ttctagtcag ttagtttttc
152101 attgtgagga attgatatgt cgttctctga tagaaccacg ctaagttggt gttcaatttt
152161 ttgcaattcg gtagtaatta tgccttgcaa catgttttat tcttttatag tgtgataccg
152221 tcaatatgat gatttgcggt ggagcatgca tgtgcttact agaagtgctg ctctggtggg
152281 cattttaggg acaagaataa attcttctct ccactatctg aacttccgtt attcttctgc
152341 acgtaattgc cgtttttagg attttttgga gttgtcacgg tatagatatg tcttattgcg
152401 tgatttcacg gtgtcttgca cacaacattt ccaggtcaca atatttggtt cgaggttccc
152461 agcaagaatt cattatcctt ttcaatgtgt cgcattaaat cattatccaa aaacaaaaga
152521 acttaagaag tacaaaagac acttgaagta tgctagcgta agaaatacgg taaccaatat
152581 ttatatgtaa catgcttatt ctgtcatgat ttcacagttc aaactacatt cctattcaaa
152641 atcatcgcgt tagtgagaca aaatcggtgg gagagatgtt agacaaaaag atgacaacat
152701 tggaaataaa ccacgacgaa aaataccttt gaaaggatct tttttcgatt ttcctgtgaa
152761 tttgtaggct tttgatggta cgagggtaaa ccaaactgga cgggaaatca ccattattag
152821 tcctatgtag agcctcgtca ccatacctat ataaacataa ctattctttt aagtacttaa
152881 acggcttttt tctgaaacaa atagccaatg ttttcataac gaagattcca aagttactta
152941 acgctcttca ggcacttcct tatttattat gacacgtaca aaataataaa ttcgtagtta
153001 taagattatc ttatcatatt taaaatatct cttctttcag ttgaaattgg gcccaaaatt
153061 tttaccccat agcgttaaaa ttaaacaaaa actgctattt cggtgacaaa ttgtaaaaat
153121 tctgaaaacg gaagaaacaa aaacgtttaa aatgattaaa ctttggtaaa gcaataatct
153181 acaaataatt ggaaaaggaa tagtaataaa gatggggaga attatgaaga agaatgtcat
153241 aaaaaacact gaaaacaatt aacgagccat gggtaaaaga aagaagtcaa caagaaagcc
153301 taccaagaga ctggtccaaa aattagatac gaaattcaat tgtttatttt gtaatcatga
153361 aaaatcagtt tcatgcactc tggacaaaaa aaatagtata ggaactttat cgtgcaagat
153421 ttgtgggcag tcgttccaaa cgcgcataaa ttcattatca cagcctgttg atgtatatag
153481 tgattggttt gacgccgtcg aagaagtcaa ttctggccgt ggaagtgaca cagatgatgg
153541 tgacgaaggt tctgatagtg attacgaaag tgattcagag caagatgcta aaacgcaaaa
153601 tgatggcgaa atagattctg atgaagagga ggtagactcg gacgaggaga ggataggcca
153661 agttaaaaga ggcagaggcg ccttggtaga tagtgacgat gaataatccg gtcctgagaa
153721 aaaaccatat ttacttaggt catatatatt ttatatttta aagcaaccac ccgtaagcat
153781 ttaagtctct taagccaaca aatcgcctcg ccatcttaat catcgtcatc agtatcgaat
153841 atagattttg gtgggaaagc ggttttaacg tggtccgcta attgcatctg tccatttcca
153901 tcgttcgtgg gacatctatc aatggtaatt gcgcccacct ttgatttcaa taacgtgaaa
153961 gtaccattgt tatttttgtc tggattatta ggcaatagtt ggctagcttc caaccgctgc
154021 tgctggtcct gttgtatatg actttgtata tgcctttgtg gcgcatcctc acatttgctg
154081 aaatcgaatt cgggaggtgg tgatgctggg ggcgatatca ggaacatttt ttcactctct
154141 ggtaccttca agtattgttt agttaaattc ctttgtccgt cttgcaagga gtagctgaag
154201 ttaaaatttt ccatttctaa agcacgagac gcatccataa catgctgaga tatatcatga
154261 ctggggcaga tcaacagtat tcttttaaac cttttcaaaa taatcaactg tagtggttca
154321 ttttcattga tttgaaactt ccttaagata ttcttggata gccaaacctg gattctttca
154381 acattatcat tatcaacaat gtcgcactta tccgaggtta taattatcgt atccgttata
154441 atattaccca tctgcagttc tgtgttttat atatcggttg gtttattgct tgatcttttt
154501 ggccctcttt ttttcatgga attactgtat ttaaaaagaa aaccatactt tatatagaag
154561 tcattgggca gaagggtctt gtcaacgagc cgcctaggaa ctacacctga cagcaacttg
154621 cggcaagata gtaagatagc ataattcaaa gcctcttgaa ccttacagcg ccttgccgcg
154681 gtttggtaaa cttctaaact gtgtatgtta cacgtgaagc gaggcttgga acacctaaga
154741 agagatcctt ttcatattta ctatccatca acactgcgcc ttttcgtgat gatgcatttg
154801 atagtatggc agatgtgcta cggtacttcg atctaatgtg ctcttagaca gatatgctaa
154861 ataatttcaa tctaattcgt ccgcgttgta aattaagaaa tcatgtaaac gttatatcaa
154921 gaaataacaa tcgaaggata gttcaaaaaa tctgacataa aaaggtactt aaaaacacag
154981 gttgcataat atgccaattg ttcggtggct attattgaaa agcgcagtta gaggttcttc
155041 tctaataggc aaagctcacc cttgtttaag gtctattgct gcacacccta ggtatttatc
155101 taatgtgtac tcaccaccag caggcgtcag tagatcactg cgcatcaatg taatgtggaa
155161 gcagagtaaa ttaactcccc caagatttgt gaagatcatg aatagacgcc ctctgttcac
155221 agaaactagt cacgcctgtg cgaagtgcca aaaaacgtca caattactaa agtatgttta
155281 cacaaaagct taacaaagaa acaaggaaaa gatatacata atataaatta ccactgatta
155341 ttttgaacat gagaccgaaa taccaggatg tattactagc cttgtttacc attcttcaac
155401 tggtgattac aaagtgagtt ctcattcatt gttaccctca tattcttatc ttctgcagca
155461 ggaaaaaggg atttacccaa ctaattgact ttgatagaat tgtgattgca atagcttagg
155521 taatatttca gttagactac gacatccagt tatttttttc tatttctctg ctcgttaccg
155581 acctttgagt tcttactaac ttacattctc tattaattgt acccaaaagt acgaaggaca
155641 actaaaatga ccagtaaaac cccaaatcgt gaaattcttc ctgataatgt cgttccttta
155701 cactacgatt taaccgtgga acctgatttc aaaacattca aatttgaagg ctcagtcaaa
155761 attgagctaa aaattaataa tcctgcaatt gatacggtaa cattgaacac cgtcgatacc
155821 gacatccatt ctgcaaaaat cggtgatgtc acatcttccg agattatctc tgaagaggag
155881 caacaagtca ccacatttgc gtttcctaaa gggaccatgt cttctttcaa gggtaatgca
155941 tttttggata taaaatttac tggtatttta aatgataata tggctggctt ttacagagcc
156001 aaatatgagg acaagttaac aggtgagaca aaatacatgg ctactactca gatggaacct
156061 actgatgcta gaagggcctt cccatgtttt gatgagccta acttgaaagc ctcttttgct
156121 attactttag tttcagaccc atctttgaca cacctatcca atatggacgt caagaacgaa
156181 tacgtaaagg atggaaaaaa ggtcactttg ttcaatacga cccctaaaat gtcaacttac
156241 cttgttgctt ttattgttgc tgaattgaag tacgttgaat ccaagaactt tcgtattcct
156301 gtcagagttt acgccacccc aggtaacgaa aaacatggtc agtttgccgc ggatttgact
156361 gccaagactt tggcattttt tgaaaaaact tttggcatcc aatatcctct acctaaaatg
156421 gacaatgttg ctgttcacga attttctgca ggagctatgg aaaattgggg gttagtcact
156481 tatagagtgg ttgatctact actagacaaa gataactcta cattagatcg tattcaaaga
156541 gtggctgagg tagttcaaca tgaattagct caccaatggt ttggtaactt agttactatg
156601 gactggtggg aaggcttatg gctaaatgaa ggttttgcta cttggatgtc atggtattca
156661 tgtaatgagt ttcaaccaga atggaaagtt tgggaacagt atgttactga taccttacaa
156721 catgcattaa gccttgactc tttaaggtcc tctcatccga tcgaagtacc tgtaaaaaaa
156781 gctgacgaaa ttaaccaaat ctttgatgcc atctcttact caaagggtgc ttctttatta
156841 aggatgattt cgaaatggtt aggtgaagaa acttttatta aaggtgtatc ccaatacctg
156901 aataaattta aatacggtaa tgcgaagact gaagacctat gggatgcttt agcggacgcc
156961 tccggtaaag acgttcgttc tgtgatgaac atctggacta aaaaagttgg tttcccagtc
157021 atttcagtta gcgaagatgg taacggtaaa ataacatttc gccaaaaccg ttacttaagc
157081 acagctgatg tcaagcccga cgaggacaaa accatctatc ctgtattttt ggctttgaag
157141 actaaaaatg gagttgacag ttccgttgta ttgagtgaaa gaagcaaaac tattgaatta
157201 gaagatccta cctttttcaa agttaacagc gaacaatccg gaatttatat aacatcctac
157261 accgatgaaa gatgggcaaa actgggtcaa caagctgact tattgtctgt tgaggaccgt
157321 gtcggtctgg ttgctgatgt caagacacta tctgcttctg gctacacttc aactactaat
157381 tttttgaact tagtctccaa atggaataat gaaaagtcat ttgtcgtctg ggaccaaata
157441 atcaacagca tatcttcaat gaaatctact tggttattcg aaccaaagga aacccaggat
157501 gcgcttgata acttcacgaa gcaactaata agcggtatga cacaccactt gggttgggaa
157561 ttcaaatctt ctgattcgtt ctccactcaa cgtttgaaag tgaccatgtt tggtgctgct
157621 tgtgccgcaa gggacgcaga cgttgaaaaa gctgctctaa aaatgtttac tgattattgc
157681 agcggtaata aggaagccat cccagcattg attaaaccaa ttgtatttaa cactgtggca
157741 agagttggtg gtgcagaaaa ctatgaaaaa gtttacaaaa tctacttaga tccaatctct
157801 aacgatgaaa aattagccgc attaagatct ttaggcagat ttaaagaacc taaattatta
157861 gaaagaacct taggatattt gtttgatggc actgtcttaa accaagacat ttatattcca
157921 atgcaaggaa tgagagctca tcaagaaggt gtagaggctt tgtggaattg ggttaaaaag
157981 aactgggacg aactcgtaaa gagactacct cctggtcttt caatgctagg ctccgtcgtc
158041 acattaggta cctctggctt tacatcaatg caaaaaatag atgagattaa gaaattcttt
158101 gccactaaat ccacgaaagg tttcgatcaa agtttggctc aatcactgga cactattact
158161 tcgaaagcgc agtgggttaa cagagaccgt gatgtcgtca acaagtattt gaaggaaaat
158221 ggttactatt aagaaaaaat ctcttttcta gccattttgc ctttttatat agtcaagtat
158281 ctatatgtga caaatacttc ttctaagctt ggccttctga taggcttagc ttgcagtggt
158341 tgcaaacata cataaatcaa caaaaaagta cggcttaaaa ttttggtatt catttatttc
158401 aacccgtgca cactggaaat aaatctgtac ataacagcat attttgtttt tgaaaaaatt
158461 tctgtgttcc tccgatgtgg gaagaatttt aggatcggct aaatttcgta aagtatcagt
158521 aacttggtat ctctgtataa gcggagtcta atttcgataa caagcaactt catcgtaaca
158581 ccttccaaca aagcaaagat agatatccca aaatggtatg ttagtatcca ataaatgcag
158641 cgcaactgga ccagtgaata gaacaataca tatagataag tcgcaaaaag aaaagaatac
158701 atgtggtgga aaattttgca ccaagagagg caagaactat gaagaaagac ttttgaaata
158761 tttcaagcgg ttgctacata tagtggataa gattcaggat ggacgtatga gcttacagtt
158821 cattgtaggg gaatataaaa ttctgatgat ggcgaacttc attcccagca actcaagcta
158881 ttgttatttt tctattctgc accgagatga ggagaaaaaa ggaagtttac taacagttag
158941 atttatttct tattcgtcta caacaggttt tagttcaaga tttattgcac ccaactgcag
159001 cttctgaagc aagaaagcac aaattaaaga cattagtcca aggtccaaga tcgtacttcc
159061 tagacgttaa gtgcccaggt tgtttgaaca tcactacagt tttctcacac gcccaaactg
159121 cagttacctg cgaatcctgc tcaacaattt tgtgcacccc aactggtggt aaggcaaagc
159181 tttctgaggg tacatctttc agaagaaagt aatttcatta ctagacagat gaaacgaaat
159241 ttacttcaaa agaagagcat taataaagtg attcaattat ggaaccagca gggtaggttt
159301 tatcatatat aatatacact cagttgtcat ctttattggc tttttagaaa cgctgcaaca
159361 aactgtacta tatatatatc atattcacgt atgtagaata ttaaagtatt gaatatatta
159421 atattattac tttatttcca gttacttaca atttcctatt ttctatttac atgttgtaaa
159481 aaatcgttgc cgtgaaaagt ggacaatttc ttcattacct caaagtttga gaactgatga
159541 tcatcaaatt gaagagagtc ctccaattca ttataagatt ccatagcctt tctagctttt
159601 tgacgttctt cctttttcaa ctgcttgatt ctctcctttt ctagcttgtg gaacttctta
159661 acattcaagt ctcccagccc tttaatctgt gttttggccg ctgaggccca taaatcacct
159721 ttcttactct ttctggcatc gtggtatatt tgtttagaaa acgaccgcga aaccgtccat
159781 ttttcaagtt ctcctgatgg cgcacataaa tccatcataa catgaccttt acgtttgaca
159841 ggatcattga taattctagg ccaggaattt tgcgtgtcat cacccagtga tccaatgtca
159901 tatttgccgt tcacattttc attccgtaat ttcttaattt ctttcaacgt attttcgtcc
159961 ttatgtgatc tctcgaatat taaataggag tagtttaaaa tttcatagtc acgaccattt
160021 cttcttcccg ttccttttag cctcgacgca tttccttgag aaccatccca tgaagtagcg
160081 agaagtttac ccttctttaa ctctatactg aatttgggac gcttgatgct tttttgaaaa
160141 ttgcagaact ttaagtcttt accctcttta tgagtataaa agttaggatt tccaacctgt
160201 aagggacatt tcctttgatg tggacaaggt gcaatcacct tcagaaaata attactggaa
160261 atgtttccta attcagcatc ttttttgcct ctgactgtta ctcccctaga ccaaggtctt
160321 ggtatttttc cgaattcatc tggaaagttt tcaggtctaa gcgtaatttg ccttgccctg
160381 gctataatct cgaatcccat tgggttgcct cgttcaataa taacaatgtg gcctccaggc
160441 gctagaatat ttaagtagtg ctcaatattt tcatccacct gaattggaaa ttgattcccg
160501 tcatgaagaa gttgatgcgt taatattatg aggtcatatt ccttagatgc gggaatagaa
160561 gaccgcaagt tagtcataat gtttatcttt tttgtcatca cttctccaat atgttcatcc
160621 tcttgaaagt ttttgttccg tctatctgtt tcctgctctt tctctgtaga cacattttct
160681 tctacagtat cgaccacctc gttaagttgt ctgctcaaaa tgattttggc tctttcttgc
160741 atctccgcat tccctaaaat aacggcatct tttagatcag gtctataatt tgggcctaaa
160801 atatcattca aggcaactat accagtcgct gggccatatc caacatcaag gattctttga
160861 ggtttaaaat tatcaggacc tacccttttt tgtaattctt tcagactttg gaaaatagaa
160921 ccataatttt gtaaaaaaat ggacgctata tgtgcatcca cttccatttt ggttctacag
160981 ggacgatgta atgaatttgg ttcctgaatc tctttgtaat aatttgtagc aacccttcta
161041 agattattgg gaatatgtac agccataata ttattgttga ttgctttgct tacatcagga
161101 ttcaactcta attggtcccg gtacgactgg ccctgaagtg ttttggaaag taatctgagc
161161 tctttagaat tagttgcttg agtggtgcta gcggtttcat ctctgtacga cggaagaaca
161221 ttgattcctc ttttatttga gtctataaaa tccgccaaat ctaactttgg taagtttaaa
161281 cttgtgaact ttgagctgaa ccggacattt tgtggtagga tactgaagca tcttttcatc
161341 attttaccta aactagacgg gccaccttat gtcctaaagt gtcagaggtt ttgctgcaat
161401 actgttctta atttttcacc attcactttt ttcatctagt ggcggaaaaa aataagagat
161461 atggaaaaca aatatgaacc atcattaaac ttgaaaaaga tgagaagaaa agaaatagtt
161521 aggctttaag tgtctgtatt gatcaattaa ttattacttt accactgctg tttattagca
161581 taatagcaca cgggatcaga atgcttagta atacacttat tattgcctgt ttattggtga
161641 tagggacaac catagcgcta atagcagtgc aaaaggcatc ctccaagaca gggatcaagc
161701 aaaaaagtta tcaaccatct attatcattg caggtcctca aaattctgga aaaacgagct
161761 tgcttacgct gctaaccaca gattcagtaa gaccaactgt tgtttctcaa gaaccgttat
161821 cagcagcgga ttacgatggt tccggcgtca cgttagtgga cttcccaggc catgtcaagt
161881 tgcgttataa actctcagat tatttgaaaa caagagccaa atttgttaaa gggttgatat
161941 ttatggtaga ctcaacagtt gatcctaaga aattaacaac aacagctgag ttcttggtag
162001 acatattatc aattactgaa tctagttgcg aaaatggtat tgatatctta attgcatgca
162061 ataaaagcga attgttcact gcaagaccac catcaaagat caaggatgct ttagaaagcg
162121 aaattcaaaa ggttattgaa agaaggaaaa aatcgttgaa cgaggttgaa agaaaaatta
162181 acgaagaaga ttatgcagag aatacactag acgttttaca gtctaccgac gggttcaaat
162241 ttgcaaattt ggaagcatct gtagttgctt ttgagggcag tattaataaa agaaaaattt
162301 cccaatggcg cgaatggata gatgaaaaac tgtaatataa ttataattta taactagatg
162361 aacgatagat agtttaaaaa caagcattta acatagctct agattccgta cgcagagaaa
162421 gacatagttg catcatcgac acatgcaata tcaaaagtaa ctctttttga ctgctggtgt
162481 aaaaaacact cacgatgggg gtcgaaccca taatcttctg attagaagtc agacgcgttg
162541 ccattacgcc acgcgagcta atatttgttt gatgttccag cagttatatg atctaattat
162601 gcgggaaaat aattgaagat aagtagtttg atgtattttt attatagtat tatattttct
162661 gatttggtta tagcaagcag cgtttttttt cttctttacc ataatcattg taccaggaaa
162721 ttttgttcat aattattgtg ttgattgtca atggtcaaag gtacaactaa tgaagattaa
162781 atatggtgaa taggaggcct gctagccacc gtacatttaa tatgtccgcg tgttggaata
162841 aaaatcaact atcgtcatca actagtggtt atactaccag tatattatct tatatggtgt
162901 caaatgtgga catgatgaca taaggtatga gaaactgtca tcgaagttag agaaagctga
162961 aatacaagga tcaataatgt aataggataa tgaaacatat gaaatggaat gaggaacaat
163021 cgtgatatta ttatgtagaa atatcgattc ctttttgggg atgcctatat cctcgaggag
163081 acacttccag tatattctgt atacataata taacagcctt tatcaacatt ggaatcccaa
163141 caattatctc aaaattcacc aacctctcat ggcgcatatt catcatgcat gtaactacca
163201 catcaatgtt caatcatgga cttttaacta atcttaagta ctattcgaac tgcccattca
163261 gcttttccct ttgcaattgg tgcactccta cttgaacgaa ttcgcggggt gtacattaaa
163321 ctacgatgta aacatcaagg ttattgctat aacatgtcat gtcaccatta attaccactc
163381 attccaacat actgtccctg acgaaaactg tttatgcgag cgcaaaatga acctattcaa
163441 ttaataatac tcctcaaatt gctaccacga caggctgaaa aaagatgtcg acgaataatg
163501 taatcgtgtc aaacaaacgt tatcttgact atatatagct acttaatttg aaataataaa
163561 ctatacaagt ctatatcatt gatatattca gtaagaaaaa tggagggaaa aagaaatcat
163621 caaatcattc attcttcaga cttatttctt accttggttg gcaacagcag cggcaccagc
163681 agcggcagct tctgggtcca agtagtaaga tggcttagat ggcttcaagt tttcgtccaa
163741 ttcgaagacc aatggaatac cagttgggat gttcaactta gcaatgtcag catcagagat
163801 accttccaag tgcttaacca aacctctcaa ggagttaccg tgagcggcga tcatgacggt
163861 cttaccactc aacaagtcct tggcaatgac atcttgccag tatggcaaca atctgtcaat
163921 gaccaaagcc aaagattcag tttctggcaa gacatttggg tcaacgtact tgtatctttc
163981 atcacccttt tgagagaatg gagaagaagc gtcgattggg ggaggtggaa catcgaagga
164041 tcttctgtag gtgttgaatt tttcttcacc gaacttcttc aaagtttcag ccttgtcctt
164101 accttgtaag tcaccgtaat gtctttcgtt caatctccag gatctgttga ctggaatcca
164161 taatctgtca gccttttcca aagcaatgtt agcagtttgg atagctctgg acaacttgga
164221 agtgtacaag acgtctgggt agaccttctt ttccttcaac aattcaccgg ctctagcggc
164281 ttcttgttga cccttggcag acaatttaac atcaacccaa ccggtgaata agttcttttc
164341 gttccattcg gattgaccgt gtctaactaa aactaacttt ggcattattg taatatgtgt
164401 gtttgtttgg attattaaga agaataatta caaaaaaaat tacaaaggaa ggtaattaca
164461 acagaattaa gaaaggacaa gaaggaggaa gagaatcagt tcattatttc ttctttgtta
164521 tataacaaac ccaagtagcg atttggccat acattaaaag ttgagaacca ccctccctgg
164581 caacagccac aactcgttac cattgttcat cacgatcatg aaactcgctg tcagctgaaa
164641 tttcacctca gtggatctct ctttttattc ttcatcgttc cactaacctt tttccatcag
164701 ctggcaggga acggaaagtg gaatcccatt tagcgagctt cctcttttct tcaagaaaag
164761 acgaagcttg tgtgtgggtg cgcgcgctag tatctttcca cattaagaaa tataccataa
164821 aggttactta gacatcacta tggctatata tatatatata tatatatata tatatatatg
164881 taacttagca ccatcgcgcg tgcatcactg catgtgttaa ccgaaaagtt tggcgaacac
164941 ttcaccgaca cggtcattta gatctgtcgt ctgcattgca cgtcccttag ccttaaatcc
165001 taggcgggag cattctcgtg taattgtgca gcctgcgtag caactcaaca tagcgtagtc
165061 tacccagttt ttcaagggtt tatcgttaga agattctccc ttttcttcct gctcacaaat
165121 cttaaagtca tacattgcac gactaaatgc aagcatgcat gatatagctc ctgtcaaagt
165181 atcaccttgg cctcctaccc tcttgttgct gccctcttcg ctgttcgtca acatgtcttt
165241 ttcactatcg ggtgagaata tcttatctga ctgacctttc tccaccacaa tacaattcaa
165301 ttcctgggcg atcaagctgc ccatctcgga gtgagagtct cccttcttgc ctatggcatc
165361 acatagtctt ttgaattcta ccacattggg cgtcaagatc actctacctt tggggtagct
165421 tttcagcatt tctttgactt cgctatcttg agttactaag aacagtccat cagcatcaat
165481 tactaacggg atcttgccct catgtttttc aagtatatat cttatgatat ccttaatgga
165541 ttttaacatt agggggtccc tacccaagcc gggtccaatt accacaacgt ggattctatc
165601 caataaggaa ttgattttct tcctttgttc gtccatatca acgtctaatt tggtgttact
165661 catacgaagg tatggatgaa ccattaggtt tggggtgtac gatttaatga ccgtaccagc
165721 gttgtattcg cagatgacat gtgtcaaatc acagcccatc aaggctgtag cattggcgct
165781 gaaatacggt gcccctgtat aatcttcgca tcctccaata atgcaaactc tcccaccaga
165841 ctgtccctta tgaaactttg gcaataaagg tggtatacat cttttctgcg ccaactttat
165901 caattctcta tgagacaatt ctgctaacat ttccagtgat acggtagtga tcgtattgaa
165961 ctggtgttgc taataaaatt tcaccgacgc ctatatacct atttacacct ttacatatat
166021 atctactaga tcacgttgca agacccatca catcgcatca catcacatca ctccctattc
166081 tgccctttac agcgcaaagg agtcgtgtgt gggtgtgtgc tccttttgac gatcataaga
166141 gtccatttct agtatgcaag ctggtaacaa taggtgaatg aattaggttc atttgcgatg
166201 accttcagta tccctccacg caatgctaaa ctatccccct cattatgacg cctatatcgt
166261 ataaggaact tgttacccct gacaattcaa acttcaaagg tctaagacca aacaagcgta
166321 ggaactatcg ctcggagtgt ttctccgttt gaaaaaagaa gagaaataag ggcccttgat
166381 tggtgtcttg tcgagagagg tacgtatata agaatgcagt ttgctcgcaa tgcccgcttg
166441 tgttaagtac tcttaccttt tccctcaata ctaacgtttt gaagcagcca aactaacaat
166501 agtataacgt atataggtta aaataatatt ccaagtcaaa aacatgtttt ccagattatc
166561 cagatctcac tcaaaagcat taccgattgc tctaggtaca gttgctatag cagctgctac
166621 cgcattctat tttgcaaacc gtaaccaaca ttcctttgtc ttcaatgaat ctaataaagt
166681 gttcaaaggt gatgacaaat ggatcgactt gccaatatct aaaatagagg aggaatccca
166741 cgacaccaga aggtttactt ttaagctgcc taccgaagac tcagaaatgg ggttggtcct
166801 agcatctgct ctgtttgcta aatttgtcac accaaaggga tccaatgtgg tgagaccata
166861 cactcctgtg agtgatcttt cccagaaggg tcacttccag ctggtcgtca agcattatga
166921 aggtggtaaa atgacctcac atttatttgg tcttaaacca aatgacaccg tttctttcaa
166981 gggtcctatt atgaaatgga agtggcaacc taatcagttc aagtcaatca ccttgttagg
167041 tgccggtacc ggtatcaacc ctctgtacca attagctcat catatagttg aaaacccaaa
167101 cgacaagacc aaagttaact tgctatatgg gaacaagact cctcaggaca ttttactaag
167161 gaaggaactg gatgcgttga aggaaaagta tcctgacaag ttcaatgtta cttactttgt
167221 tgacgacaag caagatgacc aagactttga tggtgaaatt agtttcatct ccaaagattt
167281 tattcaggag catgttccag gtccaaagga aagcacacat ttgtttgtct gcggtccccc
167341 accatttatg aacgcttact caggtgagaa gaagtcacct aaggaccaag gtgaattgat
167401 cggtatcttg aacaatttgg gctactccaa ggaccaagtt ttcaaatttt aagcatggag
167461 gaaagtaatt gatatttttt ttaatttcgg atcgttcaaa ttagtaaata tataaaaaat
167521 atatatatat tcatgtgtat gactaaaaat tctctcaaga aggcttggct ttaagctcta
167581 attccgtctg cattcgtaat agaaatatct ctcaagtcat gaatttagag ataaatgctt
167641 tagtttgtcg tacttcatct ttctgaatat ctaaggtgta tgcaggaatg gcataatttt
167701 cccaatcaat atcccttcct tcctctctat tagattgaga cagttctatc caattgacgc
167761 tattaaacgg tttattgctt aggagattct tatttttttg acaaattacc aaattattga
167821 taaattcagg atcccagaac atacggtgat tctcgtcctt ccacgaagca tgcgatgtat
167881 ccggttctat ttccagaatt tctaaccaac gtcttcttgg caggcacttg tccaacgcca
167941 agaaccgtgt ctcgccgtat ttggaatcat actcattctc ttcttggcaa ttcataatac
168001 cagacctttc gtcctcgtca ctggataaat ccaaatctat ttcattattg tttttttttg
168061 tctttgaagt tgacttatta ggcggttcgt ggcttctttt attatgctta atggaggcca
168121 tgaacctgac atgcaaatgg gcgctcaacc accattgagg ccgcaaatct cttagtagtt
168181 gccaggtcac tgggctgcct agttttccct ctttaatatc ttgctcaaaa aaaggcttaa
168241 gcttcaacaa gtgcttagta tcgccatgat aaacgactcc attgggccaa tcgtggctca
168301 gcataatatc aatacgatgc ttgatcataa aaagaggagc aatatcagaa attcttacat
168361 gatacagatt tcttatgtta gctttccaat tgttattttc taggtcattc caatctggtc
168421 gttgcttatt gaaatcccac tctttccata tcccgctcaa tgaacctatc cttatgcctt
168481 taaaccatat aacgttagag tatcccatat aaaaaatgtt ctttgctaca taaccaccat
168541 gtggcagaag cattaaatgt ctcatcgatt catgattacc gccaataaaa atagtaggga
168601 ctggggcttc aatctcatta ttgtagtatg atatgaaatc accgagtctt tgatattttg
168661 gtggtatggc tattgactta aaatcctgac catcacgaat actttgaaaa tctccaagaa
168721 taattaatag atcgatggga gtcttcgcat ggattcgtga cacttcttta taaatttggt
168781 ttagctgacc atgacagcac ccttgtacag caattcgcaa tttagtcata agcaaaatga
168841 taaatgtctg cccatcttaa tttttagtta catatttacg ttcgccatat gactttctcc
168901 tgctcatttt ttgtgagggc cagaaaaaca cacatctggc taatgagaaa aaaaattgga
168961 gaactaagga aatgcctcga taaaaaattg aaagtaataa ataaataaat aaataaataa
169021 ataaatagta agttaataaa taactaaata aatagagtat gtataagaag aaactttatg
169081 taaatgtata ttaataggta tatatacaaa ttagtgagtc agtggtaaaa aagtgcaaac
169141 gcacaaaaaa agtgcaatta aagaagagta tgatattctt ttccgtaaaa tacaatgagg
169201 ttcaaattag taggctctta cagttggagg tacggaagga cattcctttt cgtccaaagt
169261 gtgatcgata acccttctgt atttcaaagt cactggggca gcgacgtcct tttgccagga
169321 taatgtatgc ttcatccaat gttcgtcatc tctatttgga taatcctctc ttgcatgagc
169381 accacgggat tcctttctat tagcagcgga aacagctgtt tgggaggcac aggttaataa
169441 gttctgtagc tccagagttt caaccaagtc agaattccag atcattgatc tatcggtcgt
169501 cttcacatca tcaaaggtct tctctactgc agtaatgttc cgaacacctt catctaaaga
169561 tgattgtgtt ctaaagacgg aaacatcctt ttgcatagtt tgtttcatat tcattctaat
169621 ttctgccgta gatcttgaac cattagcatt tcttagttta tccaagtttg cgatggattc
169681 tttacccaaa tcagaaggta gtggtttgtg tggcaaccca ggctgtaaag tgtcagcaac
169741 cgtatgggca acagcacgac caaagacaac aagatccaac aaggaattgg cacctaatct
169801 attggcacca tggacagaaa cacaagcggc ttcaccacaa gccattaaac cgggaataac
169861 cttgtcttcg ccagtttctt catcaatggt taatgcctca ccattccact tcgtgggaat
169921 accacccatg ttatagtgga cggtaggaat aatgggaata ggttccttgg tgacgtctac
169981 accagcaaaa atggctgctg tttcagagat acctggcaat ctttccttta gaacttccgg
170041 aggtagatgg ctcaattgta agtacatgtg gtcctttttc ttaccaacac ctctgccttc
170101 tctgatctcc atggtgattg ctctggaaac gacatctcta caagctagat ccttggccgt
170161 aggagcgtaa cgttccatga atctttcacc ttcagaatta accaaaaaac caccttcacc
170221 acgagcacct tcagtgatta agcaaccaga cccatatata cctgaaggat ggaattgaac
170281 aaactctaaa tcttgcaagg ggaaaccagc acgcgaaacc atggcattac cgtcacccgt
170341 acatgtgtga gcagaggtac aagagaagta tgctctacca tagccaccag tggcaataat
170401 ggtcttgtgt gctctgaatc tgtggatggt accgtcttcc tgattataag cgatgacacc
170461 aacgacctcg ccattatggg tcaacagatc gagggcaaag tactcaataa agaaatgtgt
170521 gtcatgtctt aaagcttggc cataaagcgt gtgtaaaaga gcatgtcctg tcctgtctgc
170581 gacagcgcat gttctatagg cctgagcacc cttaccgtac tccttggtct gaccaccaaa
170641 ggctctttgg tagatcttac cgttttcagt tcttgaaaaa ggaacaccat agtgttccag
170701 ttcaatgatc gatttgggcg cttccctggt catgtaatgg atggagtcct ggtcacctag
170761 ccaatcagat cctttcacag tatcgtacat atgccatttc cagttatcct tgtgcatatt
170821 tcccagagcg gcattgatac caccctgagc agcaacagtg tgggatctgg tggggaaaag
170881 cttggatata caagcagtct tgtagcccgc ctcggcaaga ccaaaggccg ctctaaggcc
170941 ggcaccaccg gcaccgatta ccacacagtc atactcgtga tctattatgt ggtacttccc
171001 gtctgcagat ctggacgcgg aaccgtttac agagccctgc gtttggcgca ccaaagctga
171061 cgatgtaaat gttcttgtgt ttctgagcaa agtcaacttg gagagcgctg atttttttag
171121 cgatagcatc tttattctcg ttcttcttcg tactatgaaa ttggattttt ttctttcttt
171181 ctttctttct ttttatcttc aataaggggt tggggaggag attagtgaaa agaatatcga
171241 aagtgcaaag tatactactg gttagttata atgtgtctac tagtttatta gtgctattta
171301 agcttcaagc cgcctcgacg tggcaaaagg ttagagtcga ggatgcctga atatataacg
171361 ggtttgagca aacaaacaac caatagaaga ggcccggatc ccttggtcca gcgcttgctc
171421 ggcgccgcgt tctgcgctgt gattggtcca cccccgccct caaagccgtg actccataac
171481 gactttccag cgagcttggt acctggcaat agaggatgat cctcacctcc gctacttttg
171541 ggagctactt ttagcacgga aaggtatatt ttggactact gtatgagtaa atccttatat
171601 agacgacatt attactaaag gtagagcgag agatagtaaa agggttggtt acccggtcgg
171661 gcctttttct cgtattatca tttgtgctcg tgaggctatg aaataagaag gatcgatggt
171721 cagtagtgaa agagtgggaa gcaaagttta ttaagaagcg tataagggat tgcatcgcgg
171781 atatgaatgg aaaagaggtt tcaagtggct ctggaagaac gcagagcaac aacaacaaaa
171841 aaaataacaa cggaggcagt acaggaatct cgcatgcgtc tggctcacct ttaacggacg
171901 gcaacggtgg caatagcaac ggtaatagta gaagtagaag cagaagtaga aaatctagtg
171961 gaactacagg tggtttgcta aaaaagccgc cgctgcttgt gaacaatgaa gcggtgcatg
172021 ctagcgtacc cgacgcgtcg cacacttcct gtaacaatgg cacgcttgaa gtgagcataa
172081 ataaccctga gccacatgtg gtagatgccg tggcacgcca cttgataaga aacccgagta
172141 acagcctaca attgcaaggc ggagacatta caagagatct gtataagtgg acaaacgacc
172201 atccttcatc accatcgcag tatcagtacc caagtcaacc tgcactttcc acctcaatac
172261 cttcacaagc gccctcattc tcgaatcgta aaaggtctat gagcttttct gccgcttcta
172321 tagcatcttc ctctcacctt aacaacaact cggaggcgaa tgggaatcct ctagcggcaa
172381 taggcctggc gcccgcaccg atgacgcacg aagaaatcag ggctcctggt ggattcagaa
172441 gatcttttat aatacagaag cgcaggaaac ataacgttga tgcgcccata ccgaattttt
172501 tcaccaggaa ctttattgaa tttttgacct tgtatggcca cttcgctggt gaagatttat
172561 cggaagaaga ggaggaggag gaagaaactg aagaggagcc agaggaggaa gctttggaaa
172621 cggaaagcac ccagctagtt tctcgtgaac acgggcgcca tcctcacaaa tcatctacgg
172681 taaaggcggt gctgctcttg ttaaagtcat ttgttgggac aggtgtgctt ttcctaccaa
172741 aggctttcca taacggtggt tggggattta gcgccctttg tctactctcg tgtgccctca
172801 tttcttatgg atgtttcgta tcattgatta ccaccaagga caaagtaggc gtagatgggt
172861 acggtgacat gggtcgtata ctatatgggc ccaaaatgaa atttgccatt ctttcgtcta
172921 tcgccttgtc acaaatcggg ttttctgctg catacactgt tttcactgca actaatttgc
172981 aggtcttttc tgaaaatttc ttccatttga aaccgggcag catcagtcta gccacctata
173041 tctttgcaca agtactcatc tttgtcccac tatctttgac aagaaacata gccaagttaa
173101 gtgggaccgc gttaatagca gatctattta ttctactggg attggtttat gtttacgttt
173161 actccattta ttatattgct gttaatggtg tcgcatccga tacaatgctt atgttcaata
173221 aagcggactg gtcgttgttc atcggtaccg ccatattcac ctttgaaggt ataggcctac
173281 ttatccccat tcaggagtca atgaaacacc cgaagcattt ccggccatcg ttgtccgcgg
173341 tgatgtgtat cgtggcagtg attttcatat catgtggtct cttatgctat gccgcttttg
173401 gatctgacgt gaaaactgtt gttttattga attttccgca ggacacttcc tatactctca
173461 ctgttcaatt actgtatgca ttagccattt tgttatccac gccgttgcag ctatttcccg
173521 cgatacgtat tttggaaaac tggacttttc cctcaaatgc atctggtaaa tacaacccga
173581 aagtcaaatg gttgaaaaac tatttccgtt gcgctattgt cgtcctgaca tctatcctcg
173641 cttgggtagg cgccaacgat ttggacaaat ttgtatcact ggtaggctcc ttcgcgtgta
173701 tcccattgat ctacatatac ccgccattgt tgcactataa ggcgtccatc ttatctggaa
173761 cctcgagagc caggcttctt ttagatttaa tcgtcatagt atttggagtt gctgtcatgg
173821 cctacacgtc atggcagacg attaaaatgt ggagccagta atccgccatt tttgaccgag
173881 tacatcatgt acagacacat atatatatat ttatatatga ctcgttatct atatgcatct
173941 ggaacacaca taccttgttt taattatgat tagcataaat gtactatcct tgtcaatttg
174001 gtatggctga gtttacccgg acgagaggaa aaggtatagt gaataggatt accgaatttt
174061 gccacccgaa aactaaacta gcatgcagct tactatacaa agaactgggt atatacagta
174121 ttttccaagg agatgagaat tcaaagcaat attcaattga gatatttttt tgaaccatcg
174181 taataaatca aggaagttag gaactatacg gaatgccacc aaaagaagac tgggaaaaat
174241 acaaggcacc tttggaagac gatgataaaa aacctgatga tgacaagatc gtacccttaa
174301 cagaaggtga cattcaagtc ttaaaatcat acggtgcagc tccatacgca gccaaattaa
174361 agcaaactga gaatgactta aaagacattg aagcgagaat caaagaaaag gccggtgtga
174421 aagaaagcga tacagggtta gcaccctccc atctatggga tattatgggt gataggcaga
174481 gactgggcga agaacatccc ttacaagtcg ctcgttgcac gaagatcatt aaggggaatg
174541 gtgaaagtga cgaaactacg acagataata ataacagcgg caatagcaat agtaatagca
174601 atcaacagtc tactgatgca gacgaagacg atgaagatgc caagtacgtg ataaatctta
174661 agcaaattgc caaatttgtc gtcggattag gtgaacgtgt ttctccaaca gatatagaag
174721 aaggtatgcg tgtaggtgtc gataggtcga aatataatat tgaacttcca ttgcctccaa
174781 ggattgaccc atcagttact atgatgaccg ttgaagaaaa gcctgacgtt acttatagcg
174841 atgtcggtgg ctgtaaagac caaattgaaa agctgagaga agttgtcgag ctgcccttat
174901 tatctccaga aagatttgct actcttggta ttgatccacc aaagggtatc ttattatatg
174961 ggccacctgg tactggtaag acattatgtg ctcgtgctgt tgctaataga actgatgcaa
175021 cttttattag ggtcattggg tctgagctag tgcaaaaata tgtcggtgaa ggtgctcgta
175081 tggttagaga attatttgaa atggctcgta ccaaaaaggc ttgcattata ttcttcgatg
175141 aaatcgacgc tgttggtggt gctcgttttg atgatggtgc tggtggtgat aatgaagttc
175201 aaagaactat gttagaactg attacacagt tagacgggtt tgaccctcgt ggtaacatta
175261 aagtgatgtt tgccaccaat aggcccaaca ctttagatcc agctttattg agacccggta
175321 gaattgatcg taaggtagag ttttcattac ctgacttgga aggtcgtgca aatatcttcc
175381 gtattcactc taaatcaatg agtgtggaac gtggcatcag atgggaactt atctccagac
175441 tgtgtccaaa ctctaccggt gcagaattaa gatctgtttg cacagaagcc ggtatgtttg
175501 ccattagagc aagaagaaag gtggctactg aaaaggattt cctgaaggct gttgataaag
175561 ttattagcgg atacaagaag tttagttcca catcgcgtta tatgcaatat aattgacgtc
175621 aatgtacttt tttattatat attatgagaa gggttaataa aaacaacaag tacaactaca
175681 actatcgaga taaaaaggat acgagagtat cccctcaaat agagaaagaa ttagcgtata
175741 taatgctaaa gaaaattcac gtttattata tattattatc ctcattatta ctgttactat
175801 tattattaaa tgttttattg aagtcagtgg cgtccttatc tatcattccc accaactaac
175861 gagtcccatg ccatcagttt gacaactacc taatagggca tatgctggag gtttttcgtt
175921 ttgaggagtt tcttcattct taccctcaat ctcattctct aattgagctc tttcctccaa
175981 ttctcgttct ttgggtgatt ttggcttcac atcaacaaaa acttctcttt cgattctgaa
176041 tctaattttt tcatttacat cgaaatatag tttcgtctct tcatccatgg gccaaatcca
176101 tgcactttct tcaggggtat aatagcaccc ttcgaataac atattttgtg ggataaaaat
176161 gtcatcaaat atacctaaca gtgaaacttt tatgccttct gctgtacatt tagaaatcca
176221 tccagttact atctcaccta gaaacggttt gaaaacaacg gctcgaaatg taacgttaat
176281 ataggatgat ccatcgcctg gcttcaattg gccttcctcg acggttaata agtcgtaaat
176341 cgtaatacat agaccgacat tgggaataat cttgttggcg aacttattat ttaactgatg
176401 tgtgattgcc gatattgtat cgcgatggaa ttgatcgggc gggattcgta ccaagtcagc
176461 gatttttgaa aggataaaca tattaccttg ttcaatgaat tttctaattt aaatagtact
176521 acagaatgtc tttatactac ccgatagttt cttccgaata acgcttcttg cgtctatttc
176581 tgcacatggc ttgaatattc gttattatga tacgaaatta actaatccgt ataacgcgac
176641 tgaaaatttg tcaaataaaa attttaagcg atgagcatcg cctgaatatt atgagcatct
176701 aaatcagggt tcttaccgaa tcctacgagc aaccagtata gtatttcaaa gactttaagg
176761 ggaatataaa aagcacgaag atgtcgaaga aatttagctc taaaaactcc caaaggtacg
176821 tggtggtaca cagaccccat gatgatcctt cattttatga tacagatgcc tctgcgcacg
176881 ttttggttcc tgtctccaat ccaaataaaa cttctccaga agcagatctt cgaaaaaaag
176941 acgtgagttc aacaaaacca aagggtagga gggctcatgt gggagaagca gctttatatg
177001 gtattaattt tgatgattct gaatacgatt atactcaaca tttgaagcca ataggtctcg
177061 accctgaaaa ctccatcttt atagcatcca aaggcaatga acagaaggtc gaaaaaaaaa
177121 acattgaaga tttattcatc gaacctaagt atagacgtga tgaaattgag aaggatgacg
177181 cgctacctgt gtttcaaaga gggatggcaa agccagaata tttactacac caacaagata
177241 ccaccgatga aattagaggt ttcaaacctg atatgaatcc tgcattaaga gaggtgcttg
177301 aagctttaga agatgaagca tatgttgtta atgatgatgt tgtggttgaa gacatcagca
177361 aaaagacaca acttcaaggc gataactatg gagaagaaga aaaggaagat gacattttcg
177421 cacaattact agggagcggt gaagcaaaag atgaagacga attcgaggat gagtttgatg
177481 agtgggatat tgataatgta gaaaattttg aagatgaaaa ctacgttaag gaaatggcgc
177541 aatttgataa catcgaaaac ctggaggact tggaaaatat cgattatcaa gctgatgttc
177601 gaagatttca aaaagataac tctatactag aaaagcataa ctcggatgat gaattttcta
177661 atgcaggttt agacagtgta aatccctctg aagaggaaga tgtgctgggc gaattgccct
177721 ctatccaaga caaaagcaag acggggaaga agaaaagaaa gagccgtcaa aaaaagggtg
177781 ccatgtcaga tgtatctgga ttttccatga gttcaagtgc cattgcgcgt acagagacga
177841 tgacagtact ggatgatcag tacgatcaaa tcatcaatgg ttacgaaaat tatgaggaag
177901 aactagaaga ggacgaagaa caaaattacc aaccatttga catgtcagca gaaagatctg
177961 attttgagtc aatgcttgat gactttttgg acaattacga actggagagt ggtggccgta
178021 aactggctaa gaaagataaa gaaattgaaa ggctgaagga agctgctgat gaagtaagca
178081 aaggtaaact gtctcagaga agaaatcgtg aaaggcaaga gaaaaagaaa cttgagaagg
178141 tcaccaatac actaagcagc ttaaaatttt agaggagtag aatgagatga gaaagcacct
178201 acattacaag tactgtgtag acatgtatac ttagcctaga atgcattgat gctaaaatac
178261 atcctgccca ccgggtaata attatgaaac gcggcggtgc tctttgtgga tttcggagaa
178321 agggggtgga ggaaggaggt cgattttcat tattcaaata ttgttttagt ataaagaaaa
178381 ccggcgtgca ttgcttcaaa gagccgttca aattagtaac cgtttgagat atcttgtctt
178441 actactcgta ttccgcagat aaagtacatt ttaagaaagg aagtaaatac acataaataa
178501 atagcaggaa gaaaatgtct aacgaaattg aattactgca gaagcaagtc tctgaattac
178561 aagacttagt gaagaagcaa agtctgatta tctctaagac aggagagcgt gtgctggaat
178621 tgcagttaga taaacaaaag cacgacgtaa ctgattttga ttcgaaattc tctaaatcta
178681 tctcgaagaa atcaggatcc gctactcaat tcgatgccac tgattttgcc acaaatgaag
178741 atctagtgga attagtcaaa gaactacagg gtgagctaaa tttcatcgag gaaaggtcta
178801 tcagaagact tgttaactct ttgaaaaaag atgatgatga cgttatagcg ccactgccta
178861 atgcagatgg tgatattcct gctatttcag acggagtgtt ccctaagtcg ttgaaagaat
178921 ttaaagacat cccagactta aaactggtaa gacttgctaa attctacgaa agattgccac
178981 caactctaaa ggaacaagaa gattttgaaa acttcctgga aggtaaggtg gaagcctttc
179041 acattaatga gaccactgat gaagagattt ctaaggagtt ggaaaagttc tccaaagatg
179101 agctagatga tgcatttaat gatgttgccc gctatctagg tctctccctt agaagaggaa
179161 ccgaaatatg gtaaacagaa aatgaaaaaa aatgaaaaat caatgaataa gagggcttga
179221 gttccaggtt ctagaaattt ccctcactta tatatatata tatatctata tacatatagt
179281 tttgagtata tcataacagg attctctttc aatgaaacct atgttttccg cggcattgca
179341 gttaaaggat gttctagtgg tgaaaaagag aagaaaagaa ttcaaagttt tcctcccata
179401 agtataccta tactttttat ctgtgattga aagctgtata ccaacagcct tctatatatt
179461 accttgtata ccattcagta gtcttaagca tcatctaact tttgaccagg tccattctga
179521 ttggctgcgg tagcccgctc cgttttccgc tctaagcgtt tggtacttgt ataaatgtgc
179581 actggcatta tgatatcgag atccccgcat agaaatctca ggaccaacca aaaattgcca
179641 atcacaagct ctaagaataa taaacgatgt ctgcaatgat ggtcaagtta ggactgaata
179701 agtcggctct attactgaaa ccctccgcct tttcaagagc agctgccttg agctcctcga
179761 ggaggctgct ttttaataca gctagaacaa acttcctttc tacctcacca ttgaagaatg
179821 tggccagtga aatgaacacc aaagcggcaa ttgctgaaga acaaatatta aacaagcaaa
179881 gagcaaagag acctatttct ccacatctga ccatttacca gccacaatta acttggtacc
179941 tgtcttctct tcaccgtatt tcgttggtgc ttatgggact aggtttctac ttgtttacta
180001 tactcttcgg agtctctggt ttattaggtc ttggattgac taccgaaaag gtttctaatt
180061 ggtaccatca gaagttttcc aagattaccg aatggtccat caagggttcc tttgcttact
180121 tatttgcaat tcactatggt ggcgccatta gacacttgat ctgggatacc gctaaggaat
180181 tgacattgaa aggcgtttac agaactggtt acgctctcat tggtttcacc gccgttctcg
180241 gtacttattt attaacttta tgattcttta aggcgacgca cctgtttcta cacacaaata
180301 tatatatagc caattttata tatacgttcc tatatatgac ccaataccgc acttatttat
180361 tctttaagat ctttataacc caaaatgccg attaacacaa acctatattt actaggggca
180421 cattttttat ttttttgcct ttctgtaaaa tacaatagag aaaataaagg aacaaacaag
180481 aggaaaaaca ggaaaagata gcgcaagagt aatcatattc aacaaaatat cagtgatttt
180541 ttacagatat caagataatt tctttccgga tacttattga agctattatt tgttactggc
180601 aagaaaaagc aaacataggc ggtcattttt cttttgtata aagtaaatac aagaagaatt
180661 attttcgagg aataactagg tgtgcagaga tattaaggaa caaggaaaga agaaagaaaa
180721 caattcgaac aaaactttat tattctagca ctattttaaa aaactgtctt ttggcaaaat
180781 gtacttcccc tttttaggca gattatcgat aacagattac attatagtcg tcttggtata
180841 catagaaagc attatttcat cagtccttaa acttatacca caaccaatga ttaacctttt
180901 cgaatggcta ataaatttct caacgtcctc cgatgacaat accatcgaag aaaagttaag
180961 gtcagctcca actatccatg aaatgtgtgc aatttttgat atatctgtcg aggatcattt
181021 ggtaagaact gaagacaatt atatcttgac actgcataga atcccaccga tttctaaaaa
181081 cagatttaac aataaagtgg tatacttaca tcacggtctt ttgatgtgtt ctgatgtttg
181141 gtgttgcaat attgaaagac ataaaaactt accgtttgta ttgcatgatt taggttacga
181201 cgtctggatg ggaaataata gaggtaataa atattcaact gcccacttga acaaaccacc
181261 aaaatcgaac aagttttggg atttttctat cgacgaattt gcgttctttg acattccaaa
181321 ctcaattgaa ttcatcttag atataacaaa agtggacaag gtcatctgca tcggattctc
181381 tcaaggctct gctcaaatgt ttgctgcatt ttcgttgagt gaaaaattga atcgaaaagt
181441 ctcccatttt atagccatag cacccgctat gactccaaag gggttgcaca acagaattgt
181501 cgataccttg gccaaatcat cgcccggctt tatgtatctt ttctttggta ggaaaattgt
181561 gttaccttca gctgtcattt ggcaaagaac tttacatcca acacttttca atttgtgtat
181621 cgatatcgca aacaagatac tgttcaattg gaagtcgttt aacattctac cgagacaaaa
181681 gattgcttct tacgcaaaac tttattcaac gaccagtgta aaatccattg ttcactggtt
181741 ccaaatatta agatctcaga aatttcaaat gtttgaagag tctgataaca tgctaaattc
181801 cttaactagg ccttaccaaa ttgctaattt tcctactaga acaaatatca agattcccat
181861 tcttttaatt tatggtggca tagattcttt agttgatatt gatgtgatga aaaaaaatct
181921 acccttcaac tccgtctttg atgttaaagt tgacaattat gaacacctgg atttgatttg
181981 gggcaaagat gccgatacct tggtcattgc taaagtcttg aggtttattg aattttttaa
182041 ccctggtaat gtttcagtga agactaacca gttactacca tcagcaagtc tggttgagga
182101 attaccaagc acgacatgga agacaactca tccaacgcat ggtctcagtt atagaactca
182161 ctcggcagac cgttctccgt tgtctgtaca agctgatgaa gcggatgagg tccacaatgc
182221 tgacaattca aggttcttaa gacgagtgtt ttctactagt gccatagacg aggacaacga
182281 aaatgagcac caggatgata cagaagatca aatccataag gagcagcaaa gacggttaag
182341 tgcctatctg gaatcatcca aagatttacg acaactagat gccaactctt cgacaactgc
182401 gctggatgct ctaaataaag aatgaaaaga atgcgagaga aaccctatta aactattttt
182461 tgtctaggat aataatatta gcgctaatct aaaaatcgat gaactaaaga aagaatatac
182521 gtacgtttta tacacaataa atggatttca taagaagtcc ttaatatcct catgcttgtg
182581 gatactggaa attagtaaag taattaactt ccttttagca ttattcttat ttggcttaaa
182641 aaggtcacgt gaagctctat ttttttcgtt tttttttttc actgatggaa gagaaaaacc
182701 tctacataat aaggtaactt tacatattga ttgccaatga gatgttaaaa aatggacggt
182761 tcagacagta aaatacattt agaaaaaaag agaaggtctt atcagtgtat ttattcactg
182821 tgcatattag ctttttttgg actttttttg ttccattagt acttttaaaa aacctatttg
182881 taaataaaac taattctagc actattcttt gcactagaat aacacaggga ccatacagca
182941 taaattattt ggtaacaatg tcctacaata atggcaatac ttattcaaag agttatagca
183001 gaaataataa gagacccttg ttcggaaaga ggtcgccaaa tcctcagtcc ctagcgagac
183061 caccgccacc aaagagaata cggactgata gtggttacca gtcgaatatg gacaatatat
183121 cttctcatag ggtaaattca aatgaccaac caggccacac gaaaagtcgt ggtaacaata
183181 atttatctcg ctataacgat acatcctttc aaacaagttc cagatatcaa ggttcaagat
183241 acaacaataa taatacgtcg tatgaaaata ggcctaaaag cataaaaagg gatgaaacaa
183301 aggctgaatt cctgtctcat ttgccaaagg ggcccaaatc tgttgagaaa tcaagatata
183361 ataattcatc caatactagt aatgatataa aaaatggcta tcatgcttca aaatactata
183421 accacaaagg ccaggaaggg cggtctgtca tagctaagaa agttccagtt tcggttctaa
183481 cgcagcaaag gagcacgtca gtttacctaa ggataatgca agtcggagaa ggaacatatg
183541 gtaaagttta caaggcaaaa aacacgaata cagagaagtt agtagcgctg aaaaaattga
183601 gattacaagg agagagggaa ggctttccca taacctctat acgagagatt aaactactac
183661 aaagttttga tcatccaaat gtctctacta taaaagaaat aatggtcgaa tctcaaaaaa
183721 ctgtatatat gatatttgaa tatgctgaca acgacttaag tggattacta ttaaataagg
183781 aagtccaaat ttctcactca caatgcaaac atctcttcaa acaattgcta ttaggaatgg
183841 aatatttaca tgataataag attttacacc gtgatgttaa aggctcaaac atcttaatcg
183901 ataaccaggg gaatctaaaa ataacagatt ttggactagc gaggaaaatg aattcgcgag
183961 ctgattacac taaccgtgtc attacgttgt ggtacagacc accagaacta ttgttgggaa
184021 ctacaaatta tggaacagaa gttgacatgt ggggttgtgg ctgcctcctg gtggaattat
184081 tcaataaaac tgcaattttc cagggctcta atgaattaga gcaaatagaa tcaattttca
184141 agattatggg aactcctaca ataaatagct ggccaacgct ttacgatatg ccgtggtttt
184201 ttatgattat gccacagcaa actaccaagt atgtcaacaa tttttctgag aaatttaaaa
184261 gcgttttacc atcttcaaaa tgtctgcaat tggcgattaa tttgttatgt tatgatcaga
184321 cgaaaaggtt tagtgcaacc gaagctttac aaagcgacta tttcaaggaa gaaccaaagc
184381 ctgaaccttt agttcttgat ggattggtaa gttgccacga atatgaagtc aaattggcaa
184441 gaaaacaaaa gcgtcctaac atactatcca ccaacacaaa caataagggt aatggtaata
184501 gtaataataa taataataat aataatgacg atgatgataa ataaggatat atagccaatt
184561 gaaataagta gacacaaaaa atagattaat aacttattta ttacgcgata cccgtaaata
184621 tgatacgaac atctaatttc atgtgaagcg gcctagtgaa tagaaggttt gcctattttc
184681 actcgttcac tatacgtaac ttggttgtct ttttatgcaa gctgtttgtc catcgtacca
184741 acaccatctc atttcacatc ttataaatta gcctggccac taactgtctt acctcttatg
184801 ccttattgcg tttttccaag catctgctcc atataataaa tgtaactacc tatcaaccaa
184861 cttccatgta ccttacccaa ttggcctacc aagttttcgt tacattgttt cgacatgata
184921 tctagttgtt ttgtcgtttc ctgtaaattc gtttgaagct ctctaagttc gtgtgcaagc
184981 tgattatact gcctttgttt gttagcgttc attctcttgc ctgaaattct ttgtgtcctc
185041 ttcgttttga agttcaaatg ttctgatatg ttctatttcg ccatttatct tgttgatctt
185101 tcttcccacc tttacaaaaa aataacgttg atttcaatgg gcatgatata atatgagcaa
185161 tacaaaacat caaagccttc ttaggagtgt tactttcaaa catggatcta taaacaagtt
185221 attcaatgat taaactatat acagatgaaa tttttatatc aataaaacga tcttttacgt
185281 atcattcaaa agaattttgg ggcctttcta atggaaatct tcgtccactt gggcacctta
185341 tgaataccct tcctataacc aacagctttt ttatcaaaag tccaatattt atctttagaa
185401 gacatttgat tctcctttgg aaagactgat ggtttgttta acaaccttaa cgatttactt
185461 cttggcttgt atttcttttt gctctccatg gcttcttgat aagtaagacc tttatcctga
185521 catctttgga cgtggagacc taaagttaat tgctttatga cttgatcaac gtttcttaat
185581 ctttcccttt gacgggtttt ttgatgtgtg gacattctcc atggaatttt ccatagtagg
185641 ccaccagcga cggggcttgt taatttgaat gggccaaaca ttggagtctt ataacttggg
185701 tagcctttta aatacgtctc cttcctacaa agtacggata tcttttttcc ctctttggct
185761 tccctttgtc cttttgttat accgttctct tgaacttttt gaatgctctt gtacttctcc
185821 gattataaag ttgaaaacgg agtgccctgt atttatacct atgatagttt aggaagattt
185881 aaccataatt aaagccagag atacaaaagt cgaatatctt caagttatct ggaacaactt
185941 tcatatattt gataagatgg agcaaaacaa agatccgcag atgatctcga aacatagttc
186001 taggctacct atatgggtgc taagtcctcg cgaagaacaa caggctcgca agaacttgaa
186061 gacggaaaca tacaaaaaat gtgcaaattt tgttcaagca atggcagatt gtgctaaggc
186121 aaatggaatg aaagtttttc ccacttgtga taagcaacga gatgaaatga aatcgtgcct
186181 cctgttttat caaacagatg agaaatattt agatggtgaa agggataaaa ttgttttaga
186241 aaaaatcaac aagcttgaaa agttatgtca aaaacaaagc tctacaaaat aagctgtgtt
186301 gattgatgtt tttgatttac atcttttaag gattttttga tatatccatt cttgtacata
186361 aattatatac acacagccca acaataaaaa ggaaaaatta atacgaaggg tatatatgta
186421 tggtataata cttaagttca ctacaacgga cgtttatagt cagaataaat cgaggagatc
186481 ctgtgacact atattgccgc ccgaaacatc gggattgttt ttaccaccag aagatatacc
186541 gtttgagtcg ccacctagtt tcagctcctt caacccttgt acagccttgg tatcatttgt
186601 atttatttgt gtggcatcct cagatggtcc gaaatcaaat aaatcatcca aatcgcctaa
186661 agttgttaaa gtattcagca ttcctgcatt tgtatttgtt acatcatctc tttcatcaaa
186721 atccaatagc acatcatcgt tagccttgct agaaatttca ttttttgcca tgctttctaa
186781 ttcctctata tgttttcctt taactatatt ttgaacatac tttttgcctt ttctcctatt
186841 tgagtcgggc ttgaaataaa tggaacttat agtacccaat tccattaata gtttctctag
186901 cacttctggt gaaaacttct ccagtgtatt ggagatcatt ggaagtttat tttgacatag
186961 atcattaacc aaactttcat tatttggcat cgaaaggcat ctccaataca tcatagccat
187021 atctcgcaca tctaattcat gtgtctgttg tgtggccaat tctaggacgc tttgtagcat
187081 actacccgtt aaagtagcat gtagtctgac tattgtcatt agtaaagaca tctgtgttaa
187141 agcttcctct tgaacaaagt tctctataaa aatattgatt tttgactcca aatctgagaa
187201 attgttggga tgctgtccta gcaaccagac atagttgcac ttcgcaatat ctgattgtaa
187261 taacacctct ggatttgacc aagtattaaa tactgcacaa acttgtttgg ccatcttatc
187321 gtttccgggg caatgtctta ataaatcaca taatgatata cagcagtcgt cttttattgt
187381 gtcttgtctt tctaacaatt ctaggagaat atccaagact ttactgacga atgattcttg
187441 tgcatattta atacccaact gggacaaagc ttgaatagct cttgaaacaa actcaggttc
187501 atattccatt gcgtattcct ttaattctgt caacaacaaa gtacattgtt tcaagttgga
187561 aggatcgact agtcttacaa ggatatcgat cttctctaac ttgacgtaaa gaggatcgtt
187621 gaacttgaca taaaatattc tcaattcttt ggttaacagc tctggatatt tctccaatat
187681 gatcctaata tttttcaaag caacatattg catttcaggc ggcgtagaca tcagtgatac
187741 aaaagcagat gataatcttt tcattatcag actgttcgag gaatattcaa tttgaggcaa
187801 gttccttacg attaccttta ttgtagctaa aacaacggct ggattaacgt gttgtaaatg
187861 cgcagttact cgatcaatga tatcttgtgc ctctaaagaa tcttttgccg aatattccga
187921 aagagttcct agtatgataa ttctagccca ttccgtacat tcgttcaaag ctaataagaa
187981 ttgtgaaacg tgggactgga tcaaacttga aagatcaacg gcatccatat ccatattgtg
188041 aatttcaatt aatgctgctg ttgcgtttgc aatgactaaa ggatttgagt catctagggc
188101 attgaccaaa tcttcgacga cacccaactc aacgcataaa tccttgttta attggaaaag
188161 ttttgcgaca catatcactg cggtttttct aacatatgca ttatcatcat gcaaggtacg
188221 gcggagtggt gtttcaatgt attccaggat tttgtcaact cttatcattg acatcgttct
188281 gattgccatg cagcgaatta agggatttgg atcttgtgca tcagtaatga atgtgttaac
188341 ggcaagaata cataattcgg gatgcgtctc agcataattc atcacataaa gataaaccag
188401 ttttttttgt tcaacgtcaa ttgtggcaat gtttttcaag acgtctggga acagcgaaga
188461 gacatctttt cccaacgtca tttgctggat cgttttcttt attgcatctt tccgagtctg
188521 tgggtattga gatactaatc cagttcttaa ttcacttagt tcacccttac cggatatttt
188581 tggcgcaatt ctaatggagt cttttagaaa cttcttgatt cttttatcca atggtggcat
188641 agttgaaact gttttttaag tgcagtggga agctgagcaa aaaaaaaaac taagctgcag
188701 gaagtgagtt cgtacccaga taattggtgt attatgacaa taaagctaca acagataacg
188761 cttagtcatt gggaaagtgt tctttatatc gtaggctttc ttcactgaaa agagctcttt
188821 ctgatattac tacaagattt gaaactcata atatcattct gtacgcgaaa acagtagatg
188881 tgacaataag acatgaagta tataaaagaa taacaataat tatgctctgt ttgtaaagcg
188941 ttaattaaca tatgcatgtt cgtttttcag gcaatatgat cgatggtttt cagacccttt
189001 taaataatgg gtcttagtat ttataagatt atgcaatttt tttttcttgg tgaaaagaat
189061 tcttcagcta tgaataaacg tcgttggcaa ataatggcct cgattaagca cctactctgt
189121 tctctaagac ttgtgagact gtgctataaa ttccatcgca tcgctaccgc ctttctctag
189181 catggggcat tctaaaacat cagcgataca tttccaaggg tcttttagcc ctccccattt
189241 tagtaaatgc tttttaaatt tatcaccatt ttttcgactg tacggatcat cctcgaaaag
189301 ggcgtaccag attttagaag ctatcgtcct atcaaataag tagctgtaat aagttgcccc
189361 gtatccaaat aaatggccga atcttccaca ccaattactc tgatcgtcca ctaggacctt
189421 taaacgtcgt tctagtgctt gatagttttc cacaacgtca aagttatcaa tatcagaaat
189481 gattttttca tcatgaaatg attgatccag catagccatc tttgcttgag agtatgtttc
189541 acaattttga aggaagttag tgcttttcat gaagcgctgt aacatatcag cctgaattgt
189601 ttctccagtc ccgtaatgtt tgccaatctt tgtcagaatt cgtatatcct tagcgaagtg
189661 ctccatcagg atacttggta actctacaaa atcagtagca catcttgtac cacttatgtt
189721 ttgcatatga gttctcccta acattgagtg cattgcatgt cccatttcat ggaagagcgt
189781 ttcaacttca ctaagctgca aaaaacaaag acttttttta gaagcgatta gtattggaga
189841 aaaattacac accaaagaaa taacaggtaa ttgaaagtag gtaccgtctg gattctcacc
189901 gacttggatg gttgagaaat cagtttcact gggatatatt tgcctagagc aacaaactgt
189961 gaaatgagcc ggatttgaag tcttgccatt tcgttcgaat aaatcacaat aaattatgcc
190021 gatgattcct tcctcttcag atatcacatt caatcttctc acgtctgggg accatgtttc
190081 tccctcatca gtaattgctg gctctaatct aataccatat atttgctgaa acaaatctga
190141 caagccctga atgacatttc ctaatgtaaa ataatagctt atttctttgg cattgggaga
190201 gtttgacggg ttgagctgga aatatttgcc agtatagtaa tccctatccc atggtctcac
190261 gagcttcaat atttcgtccg tgtttgtagt caacggcttc ttaagatctt tggccttgag
190321 ttcagctata aatttcaatt catttgctgt cttctctata gtattgttca ttaacgtcaa
190381 aataaaatct tgaacatctt tcggattctt tgccatttta ccttccaatt gatactctgc
190441 gtaacttgtt ttgtgcatta aattagccaa gattgccctt agtttgatta agtgactcaa
190501 tcttttaacc tgtttgtcag aacaactgtg aagagcggtc cacaactttt ttcttaccat
190561 ctcattttca caacttttta ataatgcata agctgcatac ccaaatgtag gtactttata
190621 attttgccct tttacatctt tatttaattg cttcaataga aatgtactca ctttactatt
190681 atccagatct ttacatggta tcttcacaga atttgaacca ggatagtctg tatggttgat
190741 gaattcttga cctactaaac tgatttcctg agataactgg ataaactttt ctctaacatc
190801 tggattcata tagattcctg acttttcaaa atcatccaat aatattttac caactttaag
190861 ttcttctgcg cttaacttcg aagacacttc tggattgttt aaaaccgact ttagtatgtt
190921 acataaggaa acatcagtgt tcaagacatt catgaattca aacatttgtt catggcaatc
190981 ttgtgctgcc ctaacaaatg catcatctgg atgtgttgac ctaataaact cgcacaaatc
191041 aataactcga catagcgtat cgcttaatct gtccaggttc ataatatagg ttaatttacc
191101 actctcgcta aaatcattcc tcattttgtc gagaagttct tgtgcttgct gcaaagaaac
191161 ctggctaaac ttacgcaaac catctggaga agtcaaataa gggttcttga aaagtccggt
191221 tttatttttt ttaaaaagat attgtgagat cttgctatta ttagcatcct gaccattaat
191281 atttctccaa tatgaattgt cgtcgaaaat cttcttaatg cttcctggac tggtcctaga
191341 gactgcgccg gctgtggcga agaacctgag taacttattt tggcgggaag gtgacggtat
191401 ggaggcattg gacccggctt tcaatattat cgtgcgaagc attactgata ttactttcgg
191461 cgccttcact taatgttctg atacctattc ccttacacat ttagtctttg caagtaaatt
191521 catcatttgt tttgattttg acgctatata tgtatttttc tcacttttgt tcatgaggcg
191581 gtgacgtaaa attcgccata tccaatgagg aatcgacatc tttcggcatt tcaacatatt
191641 gatgaaaatt tagaagaata tatatacaaa tgtaagattt atataggcgt accatcaacc
191701 tttttaagtt cacgttgagc ttcctcaatg agttcattaa atctaatcat ctctgaaata
191761 cgaatagcct ttttaagttc cttcttagat gccctcaagc gtcccttatg caaatttatc
191821 acaccaatac cgtagtgagc aagggataat gccttaagta ttctctgatc catttcgctt
191881 tccattgcaa cttttggata ttgattttca ttggcaaagc tgataatact tttatagcag
191941 tcagccgagt actgtaagca ggaattctgg ttttcttgta acctggaccg aataagttct
192001 aaaggttctg attttttgta cggttcatta tcaatagcgt atagacttcc ttcgaacttc
192061 tctgaattta gataaaaaat cgacccgagc tctgcctggg caagcaagat gtcgtccaga
192121 ggactatccg ctagtaacat ccattctagt gttgttattt tgctattcaa ggccccagaa
192181 agattactcc gattgagaca gtaacgagta tataaatctc ttgcagtcag aagttctttc
192241 atgaaaacgc attgttcgct ttcaggttcc tttatcttca actcctgttt tcttttagag
192301 tttaaatgca tttggtagtc aggtttggat ttaccaataa atggtagacc cttgaaattc
192361 ttccagtcaa gctgttggtt gtttaaaagt tctgatttgg aaagaacatt tttgaactcc
192421 ggtgagttct ccaaaaattc tcgttgagct aataaaaggt gcattatcaa taacgttgca
192481 ttagtttcag agtctttatt tatttcattg aaccttacca aaatttgaag gtctcttttc
192541 aacaaaaaga attttctctt cgttgactta tcagtagttt tgcttagttc attatagaac
192601 tttttcagca tgtctccata taaagctgta gcatcattat acatatgtaa tttctcatac
192661 atttctccga ttttgatttc aataccggta tattcatccg aaagtagatc cacgttttcg
192721 gctttacatt cttctaaagc ttcgaggtag tactcaaggc ttttttggta gttcgcacct
192781 tctttcttaa tttctgaatg taaccccttc cttaatattt tagcaacggg tttgggaaaa
192841 gtatgatgtg gccaataaac ccaccatatg ttaaaagcga tgaaacttac gatgcctgtc
192901 gataacaccc atttctgtaa tttgctcctt cttttgaatg gtattctcca aaaactttgt
192961 tcctttaatg tagaataaaa cttgaaacgg tgattggtaa ataagttgag gttagtgagc
193021 cgttctacgg tcccttcatt tttgactgat ctatgaaggt atttccacat actaaatgag
193081 cataaatttc ttcattacaa tatctttata atgctgtttt tacgttctca ctttgtgccc
193141 ttttatatat cctaaaggat ttagttcaat tttagaaatt ttcgtgcggc tgagtatccg
193201 caaatcgttc tttgtttggt atgtattact agtcaaggat tatttaatgg tatttgttac
193261 gagaaccaaa ttacacacaa atctcctcaa tcgttttctc atcaagataa atatgagaga
193321 atcaatttat aaggtaattg ttttatctat atcaggtaca aagtatcaaa atgtggtcgg
193381 aaaaacttta taagtaatga atcactaata actcttgaaa agctggaatg taatgccata
193441 gtttaaagta aaagtaaagt tacatgccgt tataaaagaa ggaaaatatg atatatcccc
193501 ggatgccctt ggcagactgg tcctctatca atatcggtaa ttgcattgta ggatatgatc
193561 atatatctaa aaactatact ggcaagtgac agttgtgtaa gcgcaatagc tctttgcaga
193621 tatacagtga tccacatacg ataacaggaa caatcgtctt taacccactt gtttcaagga
193681 aggtccagac actttgaaga tccggctgca tgttaacatt tctcgtatac cggtttttga
193741 taaatgcgag aagattcacc ggttctaggg attggatcca cggcattcca accactgacc
193801 caaatctagt cacaataaca taatcttgtg gacgtattag cggatcaagt aagggagaca
193861 cctttttccc agttgttata gcaatgacaa atgttaatgg cgtatcaccg tacgtggtcc
193921 ttaaatggca ggctaaattt cgagctgcct tcgcattatt tgcgttgtct aatagtaatg
193981 cgattttctt tccactagta gattcataac agtaatccaa gcgatgtaaa cttcttggcc
194041 aatccacaga tattaaacct tgggatagtt gatcctttga aatacaaacc tttttttcct
194101 tgctcaaaaa gtctaaaacc gctatcgcaa ctctcaaatt aaatatttga tattcttctt
194161 cactgtatgg caggcgaact tcaagagtgc cccatgtgtc tgtgtgtaca ttgtaatccc
194221 taagagaagg gtcggtgatt tctaatggac atccaacatc atggcaccgt ttcgttatcg
194281 tatttcgtac aaattcgtca ttagaaccgt ctaatagaaa aattgcttta tttgtggaac
194341 tttcagtaat ttgagacaaa aacttgcata aaaaagcttc atcgctaatg cccacgttag
194401 taatggcgca acagactcta ctttgaccag caattatact tccagggtcc tgttttccag
194461 ctaaaccagt ttctattatg caccattggc aatttttctt agcgaagtat acgagagcta
194521 cgcttgttag cagttcgagg ttgttgcact gtaatttcaa agaactatct gcttctataa
194581 gttccttctc gatcctagaa tactctatca aggaaatggc ttcattatta atgctaatat
194641 cctcttcttt ggcgtttagc aaggaagatg tagtatacct accaatcaag accctttgcc
194701 gctgttgccc cggatgctgc aatatggatg tcaaaaattt agatactgtc tccttaccat
194761 ttgttcccgc tatatgtagg attgacaaac tatcttgggg atttcccacg tgctccaaca
194821 aacggtttat tcgaggtaaa gtttgccttc cgcttatatc atccatctgc ttcttatgta
194881 atctgttgcc ggccaaacga gcaatattat tctatatcaa aatcgtcagg aaactggtcg
194941 acttgactca agtttcatta agacaagaat ataaatttaa aaaatcatta ttgacctaaa
195001 ttggggtccc tcccacatca gaggaggctt cattttaggc tatagttcct catatttttt
195061 ttccttggca cacctgccat tctcctttgc atacctattg tatcaaaaag tgagaaaaaa
195121 acagcgcggt ttgagatgct gaaaatgagt acgccagaat aagagccgat catcagtgtt
195181 ttgaaagctt actttctgtg ctatgtgatg aggctattca tgtatatata tatgttctat
195241 taactagtgg tacttatttg ctctttttga gctaaaaact gaaggcctca gtttttcaat
195301 ttaccaaatt tgtcatgcca tttagtagcg acaacatcaa attcttcgtc caaggcgctc
195361 agcttaccat ctaaaatgga gtgccacgca gctgacaagg tctgaaattc ttcttcggag
195421 ttgacaggaa gaatctcctg caagaagata ttatcagttt ctccgatatt cgttccgtcc
195481 tcatctgcgc atttaatggc aaattgaaca acttctaaat ctagcaggtt gctgcctata
195541 cgcaaagact caatcatcca ttgagaaaat ttcacgaaat gattgtaggt atcgtcaatg
195601 gctaatatgg actctgctgt tagcgttagg tcctcgttca aagttttaga taaaatttcc
195661 ttttgtaatg actgcgttag ataatagttc agtaagtcaa acgtttcaac acatttaaca
195721 aacattgaag ctattggtaa aattaccttg tcaaacgaat ccgcctctgg gtctaattcg
195781 tttttacctt cattgataaa ctctgatgca ttatagctta acacacaatc gttgtaaaat
195841 ctcaatttct taacaaattt aatcaaagta gttctctcga atcgtagcgt agctaccctt
195901 cgcaaatgac tgatgaactt gttcagcacg tgaatataag atgagagata ccgggagagt
195961 aaggcgagta tttgttcaac taattcacaa gttccaggag tgactttgat atctttgtct
196021 ttgctcattt ttaagtgtct ggtattatgc aaaaggaaaa ttaaggaggg tttactgtgc
196081 tttctctttt tttgagaaaa atgtcttgag taaagtgagg attttactgt caaatcttta
196141 aagcttgttt tgaacgatgt cctgcattaa agtgggagtt tttcaaaacg ggaaaataca
196201 aacaaaaaat gaaaaaaaaa aaaaaaaagg gactttaact ttctgcgaga gtatgtttaa
196261 aagtatatgt aatgcacttt tggtatgtta agaggcatgc acgaagaacc attctataag
196321 agactaaaca tctatatatt catgttaatt accagtcatc atcatcatcg ccatcgtcat
196381 tatcatcatc gtcagcactt tccgcccgca ttttgtttgc tcttgctgcc aatgcagaag
196441 ctaaaccgtc gctaaacgtc cccaccggat tactctgatt atcactagtg ggtccaactg
196501 ttgcacttcc aaactgtaca ccttcttgtg cacttgaaat ggtattgtcg atttggcttg
196561 atttctgatt tgtaacgtca ttcactgccc ctgtcgctgc aacaggcacc gtatttcttg
196621 tgtctttata aggagtcata taagcagtag gaacccaacc ttctttgctt ccatcgagaa
196681 gctttgctaa agaccaacca ctaggttcat ctctgcttat aaatacaata tcgccctttt
196741 ttaatggcaa ctccgaagat gatccggaac ctggaaagtc gtatgcagct tcgaatttcg
196801 gatcctttgg ttggcccatg gggggagggg gtggtggtat tggtatgttt gcagttgcag
196861 ttgcagttgt ctcctttaac ggttctttat ttttttcaac cccttttgaa ggtggcatcg
196921 atacctggtt ttgcttggcg gatgaggatt tgtggcttga ggaggctttc tttactgcga
196981 ctttttcctt cgatgagggt tttgagctgt gtttcgagct tacttttgca gcagggattg
197041 cagatgactt tattggtacg gtcttatccg gtttaggatt gtatgctgcc tgtgcagcgg
197101 tagctgccaa agataacgga ttcacaggtt tttgcgaagg gagaggttgc ttttttgcag
197161 catccctatg acttctatgg ctatgtgtat gcttatgagt agatttgtgt ttactctttt
197221 tgcttttgat aggtttcccg ctcaacccac ctggattctt aggtttttta ttcgatttgg
197281 agttagcagg gtgtccacga cgcacgtata ttgtacttga cttgtagatg tcaccgtatt
197341 tcggtgctga atcgcttatc tttgagcgga cagtgtgcaa cttgtttggt tgtttgtgat
197401 actcaatcgt gggaccaact tttatcatta tcttttcatt taattttttc aaacgtgtca
197461 ttaattccgt cttgaaaggc gtgttaatga gtggatcgga ttgtgtacta ttaacaagga
197521 taacgcccat ccaatcgtct tggaggtttg ttaagctcac ttgtttaatt ttaccgacat
197581 caattttata atcttgtgta tatttcatag cattctgttc ccgtgtttgt ccaataatat
197641 aaaatgtctt ttttgttaag ataaacactt ttttcaatct ttgagctgat ctgccaaatt
197701 tagagtgcag gcattccccc tttatcgaaa aaacaacttt atccttaatt cctacctgtc
197761 ttctgatgta cgatcctttc gttttagact cattgcagga taagtaatca cccataaaag
197821 ccctgtatcc aagtaaagac atggatcttc tctctttttt acccgctaaa agtttggttc
197881 cataatcacg aagcttgacg tacttgtttc cacccttttt ctctctgata gtacgctgaa
197941 tttttatcgc agcatcaata cgcctttgaa gaaaccttct ccatgctctc tggattctag
198001 cagccatgtt gtaccagtat ttatcacgca tgtcttctag agcaaataga gattctggag
198061 ttttaatgaa tacgcttgtc actccaagtt gaaattcttt ttctggtatc atggcatctc
198121 ttaaaataag cttgactgcc tcaagggtgt ccccatccca agtgtaatca ccagcatatg
198181 aacaatctgg agatagtaaa taaaatcttt cgacgaattt ttcgaaagtt tgtctgtaag
198241 cgaaaccggc tctcctgata cgaacatttt cttgcaaacc caaatatttt acttgatgta
198301 gcacttggtg atcatcataa tcatttggtg atttagtttg attaggcttg attgttctga
198361 tataggaagg ctcagctttt gacaaagttt ccaccagttc atttgcactt ttaataattt
198421 tgtcacctgc tgttggaggc cgtctctttg aatctttgtc aacatcatca ggaaaaattg
198481 tggaaaggaa tgtatttgtc gttgttccaa ttaattcaat taggtccttt tgaagttggt
198541 ctttattttt atcggtgata ccattgatgt cataggtgac atctccagcg taatgtttaa
198601 taacaaattt gttggccctt aattcgaagt atggatttga attaaataag ttaagtcgtt
198661 gagcaaacgc ctggtcagcg gcattggagt ctgcatgagc agttgcaata gagtcattca
198721 ttgcagcaag aatgcccggt ggatttttcg cctcgattaa atcacagaca actttattgt
198781 caaagtattt gatgggggtc catttgattt tttctctttc ataagtttct tgctcagcct
198841 tcaaagtcaa ttggataaaa atctgttgta acttttcatt aacataattg atacatattt
198901 gctcaaaaga gttgtgttca aaaatttcga agccgtaaat gtctagaatc ccaattgatt
198961 tatcagcacc aggaaatgcc tgcaaagata cgttaaccct atcgacaatc cagtcgaata
199021 aattattata aattgcctta gcaagggcgt ctctcaccgc agttgcttgg actgggttca
199081 aaggtacatg ataaactgag cctctcttca ttccatgact ggtttgcatg attctttcca
199141 ctaaacattt taccagtaac gaagcatcaa cctgcaacaa ataagcgaca aaatcagtca
199201 ctgaggtatc tcctacctga gcattgccct cttcattttc tataaaggaa atgttaccaa
199261 tccacagaat tgccgccagc atcctaaaaa tttggtcttg ttcttcctgg actaaaccaa
199321 tggttctcat agcctctaac gtgccttcgt aatcttttac gtcatcaatt gtatctgcag
199381 tagtacagcc agccgcagca gtgtaaatat attgctcagg catttgcaca ccgaacatct
199441 gtttatatgt atcagatgct cccttagtga attggtaaaa aatatgaaag tttctttcgt
199501 tcttaatttg accaacaact ctttgtttct ctagcaaata atttgtgata ttacctgcgc
199561 aaggttcaaa ttgtgagttg aatttaattt ctagatactt cccgtgcctt gaagaattgt
199621 tgttccgcag agttttagca caaccgaatg actcgagaag tggattagta gcaagaacca
199681 tatctttgat cttcccaatc gattctgaat ggctattaga tgcagctgca atatattgca
199741 taatacgttt ggctgcttct gtcttaccgg caccagactc accagaaata ataacacact
199801 gattttcatt gtatgatttg agattgtagt acatagattc cgcaatagca aacacgtgtg
199861 gtggaacttc aagtctattt tttcctttat atgactctaa aacggcattt gtatatattc
199921 ccaaatcgcg gaacggattt acactaatta acacatggcc aatataggta taaataattc
199981 cattcttaaa tctttttttc aaattttcat tgatagattc atcagatatt tttgacaaaa
200041 gtgtcaaatc agaaatacct acttctttct ttttatttgc atcaaatgta gcctttttga
200101 tttttgcaga tctcttcttg ggctccttaa cgtcctttct gcgtgctccc ttttttatga
200161 cagccattga cggttataag tatttctctt tacttttttt gattcaaatg tgatcagcaa
200221 attaatgttt tataactgga ttgttgttaa tttgctcgcg gtcaattgaa tcgagattgc
200281 tttaaccctt tataatagat tactctatat ttacttgtca cagcaaacgg tttccttttt
200341 cggtaaagct cttcccgagg tttattatat aaatgcaaat cgatcagttt acctttagtt
200401 agaaaagcga tggagctagc atcttgctac tatataatag ttgttcaaga tcgtaggtct
200461 gcctgccgag tgattagggg aggctactga agtttgtttt aatgtaccgg ttacattttc
200521 ttgtacgaaa gtatatgaag ggggcttatt acttccaagc ctatattttc tgtggcatcg
200581 attagtatag tataaaagag ggagtggaca tagcggtgaa aactatacaa gaataaaaaa
200641 ggaactaaga accctttgca ttcatataat ttcacatatg cattttttat tttatactca
200701 aatgtatgtt ctcacctagc ttgagaaagc gatgatcaaa gtgaaaggtt caaccatttc
200761 tcaaagtgct taacacatta tttgaaaaga aagggtttta ttccatccac tctattatat
200821 ctataaaaaa ttatttaaat tacccacata tttgaaagtc ccgaatgggc gctgtgggaa
200881 aattcagagc ctgccgcgat cggccgtgtt gactggtact tccacgacga cagcgacgac
200941 tttacctgtg tccaggttat aaattggagg atgctgtaag tttctcaaga cactttgaat
201001 gacacctgag tgacaagtaa gcgagatgaa tttttcttcg cttgacaatt gattaaatag
201061 ttcaaataat ccattcagtg tacgtttgtc catttcagca cacgtttctc tatgatcagg
201121 aagccacaat tcatcatctt ctgggtaatc tggtacatat tgccaatgta cagtgtggcc
201181 cgattccgtg ctgaaatcct ggtattcgtc aactgccatt gagtgagcca ctcttttgtc
201241 acaagtgtga gagcccaacg tctcccttag accttctata atgcgtgtag aaattttagt
201301 tccggccggt aattcttgcg tctccgctaa cactggtgtc cacgactcaa tgaatgtttc
201361 gagacatctt ctcattggag aactgaaaaa cacatgaggt agcataccta attgctttgc
201421 cattggtagc aagacattcg atcctgttct tctaacttga tctttaccca gaggtgtcag
201481 tttagagtca agccactctc catgttcatc gcccgaaagc aacgaccaat aggcgtccca
201541 tttctccata ccgtacctca gtatggcagc attgtggtaa ccttgaccat gcctagctaa
201601 aatcaacagc ttatagtggc gatttttggt atttctaggg atagcatgat acagttcctt
201661 ccaattctta tggttaatca attctaagtg atcatatttc gtggagtcta atccttgaaa
201721 accctcactt ggatatgcag caaaatatcc tgggactgct ctgagtgaca ttgttgaata
201781 actgttggtg atttcacgca gcagagtctt ggaaagaaat cgttaaataa catacaaatc
201841 tctcgagggt ttttttttgc aaatgacact ttttactttt tccagtacta gctagcaccc
201901 gaaaaattaa cttgactcgc acatgcctgc tgggtcatat ccgaatctgc aagaaattag
201961 gattacaaat atttattcaa acgttgcaca accacgcaat agaagataat atctgtaaat
202021 tttaatcgct ttcatctgaa aacactgagc ctcttcttaa ttttcacgga ctttttcgca
202081 gcccaggttt gaccggctaa gtacgaacct cttttgtttg gaataagagt ttggtattaa
202141 tcaattgttg gtacaaaaga ttaatagtat tacttgtgtt ttcagaatat aattgtccgt
202201 gagcgtccta actgtcatcg agtttatagg aagctaatta gtaaggactg accatgcaaa
202261 cccagcaatg aatgaaagga tataaacgag ggaagaaatg gtagcagtat taagtaaaat
202321 tgtccatttc ccctcgtgaa attatccaaa acgcggcaga agaactttta agttatctac
202381 tgtacatagt gttattgtcc tcacgtgaat tgaattgaaa ctttttcaga acattatcgc
202441 tgaactataa atgaaatttt gtaatgattg ttctgatccc atcttactaa aagcattatt
202501 gtgaagtata aaatacaata aatttcttct caaaaaaact tgccgtacat gatatggaga
202561 aataggtgaa tttagggata gtagttatta taatgagcct attatagaga atctattatc
202621 gatttctaac ggtcgtatca atctgttgta ttacgggctc gagtaatacc ggagtgtctt
202681 gacaatccta atataaacag tcttagggaa gtaaccagtt gtcaaaacag tttatcagat
202741 taattcacgg aatgttactt atcttatata ttatataaaa tatgaatcat actaagtggt
202801 ggaagcgcgg aatctcggat ctaaactaat tgttcaggca tttatacttt gggtagttca
202861 gctagggaag gtcgggtttt gtctcatgtt gttcgttttg ttataaggtt gtttcatatg
202921 tgttttatga acgttcaggg tgacgtattg tcatactgac atatctcatt ttgagataca
202981 acacaatcac gtttaaaagc cttgttggcg caatcggtag cgcgtatgac tcttaatcat
203041 aaggttaggg gttcgagccc cctacagggc tttcttttta aaacaggatg ctaaagccga
203101 caccgttcaa acacaagtgg cagcttttct cgagaacagc aatgcccaca gttttattta
203161 caattttaca ctattgacgt ggagattttt ttatcccgca tatgacctag tagaggatct
203221 ctgtcttccc ctgataaatg tcaaatgtat gacgttacca caattgtatc acggtggttt
203281 cagtctgtca tgaggaataa gggcattcag taccgacaat gctatacttg taaatagaaa
203341 aatgatgttc taaaatcggc attctcgcta tttgagattt tgtctttttt tacctggtat
203401 ttcgcgttta tattacggat gcaagaaaag gagaagggcg catcacatcg attttggtct
203461 acctataaac attctctctc tcatccactt tcggttcaat agtgcaaaaa taggtaacta
203521 acaactcaat tgaatagtaa atgtcacttc taatagattc tgtaccaaca gttgcttata
203581 aggaccaaaa accgggtact tcaggtttac gtaagaagac caaggttttc atggatgagc
203641 ctcattatac tgagaacttc attcaagcaa caatgcaatc tatccctaat ggctcagagg
203701 gaaccacttt agttgttgga ggagatggtc gtttctacaa cgatgttatc atgaacaaga
203761 ttgccgcagt aggtgctgca aacggtgtca gaaagttagt cattggtcaa ggcggtttac
203821 tttcaacacc agctgcttct catataatta gaacatacga ggaaaagtgt accggtggtg
203881 gtatcatatt aactgcctca cacaacccag gcggtccaga gaatgattta ggtatcaagt
203941 ataatttacc taatggtggg ccagctccag agagtgtcac taacgctatc tgggaagcgt
204001 ctaaaaaatt aactcactat aaaattataa agaacttccc caagttgaat ttgaacaagc
204061 ttggtaaaaa ccaaaaatat ggcccattgt tagtggacat aattgatcct gccaaagcat
204121 acgttcaatt tctgaaggaa atttttgatt ttgacttaat taaaagcttc ttagcgaaac
204181 agcgcaaaga caaagggtgg aagttgttgt ttgactcctt aaatggtatt acaggaccat
204241 atggtaaggc tatatttgtt gatgaatttg gtttaccggc agaggaagtt cttcaaaatt
204301 ggcacccttt acctgatttc ggcggtttac atcccgatcc gaatctaacc tatgcacgaa
204361 ctcttgttga cagggttgac cgcgaaaaaa ttgcctttgg agcagcctcc gatggtgatg
204421 gtgataggaa tatgatttac ggttatggcc ctgctttcgt ttcgccaggt gattctgttg
204481 ccattattgc cgaatatgca cccgaaattc catacttcgc caaacaaggt atttatggct
204541 tggcacgttc atttcctaca tcctcagcca ttgatcgtgt tgcagcaaaa aagggattaa
204601 gatgttacga agttccaacc ggctggaaat tcttctgtgc cttatttgat gctaaaaagc
204661 tatcaatctg tggtgaagaa tccttcggta caggttccaa tcatatcaga gaaaaggacg
204721 gtctatgggc cattattgct tggttaaata tcttggctat ctaccatagg cgtaaccctg
204781 aaaaggaagc ttcgatcaaa actattcagg acgaattttg gaacgagtat ggccgtactt
204841 tcttcacaag atacgattac gaacatatcg aatgcgagca ggccgaaaaa gttgtagctc
204901 ttttgagtga atttgtatca aggccaaacg tttgtggctc ccacttccca gctgatgagt
204961 ctttaaccgt tatcgattgt ggtgattttt cgtatagaga tctagatggc tccatctctg
205021 aaaatcaagg ccttttcgta aagttttcga atgggactaa atttgttttg aggttatccg
205081 gcacaggcag ttctggtgca acaataagat tatacgtaga aaagtatact gataaaaagg
205141 agaactatgg ccaaacagct gacgtcttct tgaaacccgt catcaactcc attgtaaaat
205201 tcttaagatt taaagaaatt ttaggaacag acgaaccaac agtccgcaca tagaattatt
205261 ggtcttgaac aagcactaat tttccaaaga tgttttaact gatcttaatt tatatgtaga
205321 ggatatatgt agtatatcta ttttttgctg attgacttat caattagctt cataatacaa
205381 cattgttttt gtttttcgtt actcgcgact ttcttcgcgg cagagccgcg ctacaggaaa
205441 acaagatcaa aacatgcccc tattggaagg cttaaaaaat gcttatcccg aacgagccaa
205501 cggtaatcaa cactatcgtc ataccaacaa cagttgagtt atttttcgct cccatacttt
205561 ttagaattgg tttgtttgtg tttggttaaa tttcaaagcc tttatattct ttgatataga
205621 ttactctaca atttctttgt atacagcggg aaattgacac ttcaaagttc ctctcatatc
205681 aacaaacatt aatacagttc ctgaaaatgt attcttggaa gtcaaagttt aagtttggaa
205741 aatctaaaga agaaaaagaa gccaaacata gtgggttttt tcactcctct aaaaaggaag
205801 aacagcagaa taatcaagca actgcggggg aacatgatgc ttcaattact cgttcatctt
205861 tagacaggaa gggcacgata aatccatcaa attcatcagt ggtcccggtt cgtgtttcat
205921 acgatgcatc ctcatcgacc tctactgtac gagattcaaa tggtggtaat tcagaaaaca
205981 cgaactcatc tcaaaattta gatgaaacag caaatattgg ttctacaggg acacccaatg
206041 atgccacctc aagttcagga atgatgacta tcaaagtata taatggtgat gactttattt
206101 taccttttcc gattacctca agcgagcaaa tattgaataa actattggcc tcgggtgttc
206161 caccgccaca taaggagatt agtaaagaag tagatgcttt aattgcacaa ctgtcccgtg
206221 ttcaaataaa gaaccaaggt ccagctgatg aagatttgat ctctagcgag tcagcagcaa
206281 agttcatccc atctactatc atgttaccag ggtcttcgac cttaaatccc ttactatatt
206341 tcaccattga atttgataat acagttgcaa ctattgaagc agagtatggt acgatcgcta
206401 aacctggttt caataagata tctacctttg atgtgacaag gaaattacct tatttaaaga
206461 ttgatgtatt tgcaagaatt ccgtccattc ttttgccctc gaagacatgg caacaggaga
206521 tgggtttgca agacgagaag ctacagacca tttttgataa aataaattcc aatcaagata
206581 tacatttaga ttctttccat ttgcccatca acttaagttt tgactctgca gctagtatta
206641 gactatataa tcaccactgg atcacattgg ataatggctt gggtaagatc aatattagta
206701 ttgattataa accttccaga aataaacctt tgtccatcga tgatttcgat cttttgaaag
206761 ttatcggtaa gggttcgttt ggtaaagtga tgcaagtcag aaagaaagat acacaaaaag
206821 tatacgcttt gaaggcaatc agaaaatcat acattgtctc taaatccgaa gtcacgcata
206881 ctttggcaga aagaaccgtt ctagcacgtg ttgattgtcc atttattgta cctttgaagt
206941 tttctttcca atcaccggaa aaattatact ttgttttagc gtttatcaat ggtggtgagt
207001 tgttttatca tctacaaaag gaaggaaggt ttgatttatc acgtgccaga ttttataccg
207061 cagaattgtt atgtgcgcta gacaacttgc ataaactaga tgttgtctat cgtgatttga
207121 aaccagagaa tattttattg gattatcaag gccacattgc cctttgtgat ttcgggctat
207181 gcaaattgaa tatgaaggat gatgataaga cagatacttt ttgtgggacc ccagaatact
207241 tggcaccaga actattgcta ggtttaggct atacaaaggc agtagattgg tggacattgg
207301 gagtcttgtt atacgagatg ctcacaggtc ttcctcctta ttatgatgaa gatgttccaa
207361 aaatgtataa gaagattcta caggagccac tagttttccc agatggattt gatagagatg
207421 caaaggatct attgattgga ttattgagcc gtgatccgac aagaagattg ggctacaatg
207481 gtgccgacga aattcggaac catccttttt tcagccaatt atcatggaag cgcctgttga
207541 tgaagggtta tattccacca tataaaccag ctgttagtaa ttccatggat actagtaatt
207601 tcgatgagga attcactagg gagaagccaa ttgatagtgt ggtagatgaa tacttgagtg
207661 aaagtgttca aaagcaattt ggtggctgga catacgttgg aaatgaacag ctaggtagct
207721 caatggtgca aggtagaagc attagataga cttagtgaat acattatcaa ctagtttact
207781 catgacatac tttatataaa aagaaaggtt ttcttttccg ttacttactg tgttcaagat
207841 gaagcaactg taccaatggc gcaatttaag ttctaggatt tatatttcga acgtgggcaa
207901 tacttcacac atgtgtggct tgtgtctcat ggtcatagcg tattgcctca gcttattctg
207961 attagataaa ggatttcctc tcttaccctt ccgagatccg tgtcgatggg gcggcagaaa
208021 ataaaaaaaa aaaaaggtgt tgaaaatttt ctccttgtat aaaagatatt ttgatgagca
208081 tctctcgttt gcagtagctt ctccttttaa aaatataaag gttgttttaa tcagcgttcg
208141 actttaaatt aacccaagac cccattgtta aaattcttac cttaaccacg aacggataca
208201 ttgtctggta aagaaataac ttttgtgcaa gacaacagct gacaagatga tggcttttga
208261 gaatacaagt aaacgaccac cccaggactt tgtagctcct atagatcaaa aaaaaaggaa
208321 ggtccagttt tccgatagta ctggcctggt aacccttcaa ccagaggaga taaaagatga
208381 agtgttttca gcggccatgt atagcaggtt cgtgaaatct gccctagatg atctggataa
208441 gaatgattca acccagatcg gcataattgc caatcaagta gcgcttccga gcaagaatcc
208501 tgaaagaatt aatgataaga atctcaatat tcttttggat atcttatcta gtaatatcaa
208561 caggatagaa tcctccaggg gaactttcct catacaatct atcataaact ttgagaagtg
208621 gtgggaattg cctccacaca ctctaagtaa atatatatat ttcatcaaaa tcctttgctc
208681 gagtataccc aaatggtggc aagacgtttc gatgatactg gtatcttgtt ttattttacc
208741 aatcaaacag acagtgtgtc atcatgatat gcttaaatat ttcttaagga tgattccctc
208801 ctcgatggga ttcatagata catatttggc caaatttttc ccaaataaaa atgatactcg
208861 gagaaagttg gttaattaca cttcaaattt gctgaaattg agaggctact gctctgagct
208921 aggattccaa atttggtcct tactgataga aaagattatt tcgattgatg tcgagttaca
208981 aaatgaatta gatgaattag atgatgatgt agatgacgat gatctagagg aagttgatct
209041 agaggatgac gacgatttag atgatgattc aggagacgat gatgatgaaa attgtgggaa
209101 cagtaatgaa gagttaaggt ctggagcagc cgacggtagt caaagtgata gtgaagatat
209161 ggacatcatt gaaggtatgg acggtactga agaatataat gtggagttga cgcagggaat
209221 caaagaactt tccaccaaat tggactctat cttaactttg gtaagcacgc atgtggaaga
209281 gcaagtgacg ccggagagtt tagaaagcgg tgaaggcgta ggagtcttca acactctaac
209341 aacattattt aaaacgcatg ttctacccac gtactatacc aggtcgattc aatatatcat
209401 gttccatgtt tcacaacaac aattagaact aatggattca tttttagtga cactgataga
209461 tatttcgttt gccgtcaacg aagcagcaga gaagaaaatt aagtcattac aatatttggg
209521 gtcgtacatt gcgagggcca agaaactatc cagaactcaa attattttcg ttgcaagcta
209581 tttaacgtcc tggttgaata gatacgttat cgaaagagaa gaagaagttg atcaacgtgg
209641 aggtatggaa aggtttaaac atttctatgc agcatttcaa gcactttgtt acattttctg
209701 tttcagacat aacatcttca gagatacaga tggtaactgg gagtgtgaac tggacaaatt
209761 ctttcaaaga atggtcattt caaaatttaa cccattaaag ttttgtaatg aaaatgtcat
209821 gttgatgttt gctcgtattg cccaacaaga aagcgtcgcg tactgtttca gcataattga
209881 aaataacaac aatgaaagat tgaggggaat catcggcaaa gctgatagcg acaagaagga
209941 aaattccgca caagcaaata ccacatcgtc ttcttggtct ttagccactc gacaacaatt
210001 tattgactta cagagttact tcccatatga tcctttgttt ctgaaaaact ataaaatttt
210061 aatgaaggaa tactacatag agtggagtga agcaagcggg gaatatgaaa gtgatgggtc
210121 ggatgactaa ggtctttttt cataggtatc ttcgagacat gcccgtcaca aactaatgat
210181 acactgtagt caccccatta atagttgaaa tgaggatata tagcataaat gcatttaaca
210241 cattttttag atttctagat actatagaaa cttagtattt ttattttcca cagtgtactc
210301 ttcacgatat tttgcatttt agaacgcttg tttgttctcg tcacttacta cgtgcgcgct
210361 ttacattcgc aggtctactt attaaagagt ttctgtgggg aggggttcct gagtcaaaat
210421 ctcagctatc cgaacagctt gtacttagat tacttggcac atatttatat tcagtaaagt
210481 caatagtggg tattattaat cgaaataaac agaacaagca gtaatagctc ttttttcatc
210541 tattttattt gtaactagga agaagaaaaa aacttgaagg tatacaagag caatgtatgt
210601 cacttttaat gaggctttgg atagttcttt tggtaatcta gagagtccga atcatgactt
210661 caaagtaggt gaccctaaca tggtaccaac tccccctatg gattcagatt ctgcagcaat
210721 tagtttggct ttcttaataa gtctttctat tacgtttgca atattaatgc tcatcttggt
210781 agtaatagcg gcatatgtca ccttttgtgg tgatgatgaa tcagaatacg acgaagagaa
210841 cgccttaggt acacgaactt caggaactct gcactctttg tttggtaaaa aacatagtgg
210901 catcttgttg gattcgagtt ttgcatcccc tggcgggttt gatgatgaga tcgttcttca
210961 ggaaagagaa cttgaagaat taccaaagat gtcagcgtac gaggttgagt tgtatataag
211021 agcgaaagag tttcaaatga tgagcccgcc aatggtgaag gactttggca cgtatttgga
211081 cagtgacgac cagcagttta ttaaggatcg tggcattcaa agctattttt tgctaccaag
211141 cattaatgat aatatagacg aatatggaaa ctttctaccc agttttattg tccaggataa
211201 actagatatt caattttcaa agttcaataa gagctcatcc actgtaatga actatcccct
211261 acctcacaat aggaaggacg cagtgtattt cgaagttaaa attttcagac atattcaaaa
211321 gtccaatagt atattcagta taggtttgac tactgtacca tatccttatt tcagggtacc
211381 gggcatggcc aaatactcca ttgcatacga atccacaggt aaactgagga taaataaccc
211441 cttcactgcc agcacattat taccaaaatt ggaagaaggt gacacggtag gattcggtta
211501 cagatataaa acaggtacaa tcttcattac acataatggg aaaaaattaa tggatgtaac
211561 acaaaatatt ggcattgatc ttttcattgg aattggcgcg tttaatgccg catatacaag
211621 aacatatacg agggatggtc tattggaaga cccggataat gttagcttcc gtgaagctct
211681 ctctgaaggc aaagatattg aagtcgccaa agatcttcaa agagttcacg atccacatga
211741 tgaaagtgat gaaatgacgt cagatgaggt tgaattacat gttaatttgg gccaagttgg
211801 gttcgtcttt atagaagcca atgtgaaaaa atatgcgttt gggagtgttt atggccaaat
211861 tggaattcct cctgcgtata atggaaccga gatcaagaag gatactattt tacagaaagg
211921 agaagaattg ccaccaagat atgctgacac tgataatttc tttggtagta tgaaggtaaa
211981 agaagggtca tcctctagga taacggcgca aactagtaag cccctgtggt ctgttgggac
212041 gtatgaaaga atctcttcta actttgacag agaaaataat gtttaccacg acagtcttga
212101 aaccgacgat aacaacaccg ataacaatgt taataacaac gatgagaacg ctggttgcaa
212161 tgaaaattcg ccattattgg aagatgatgg caataaaaga ccggaaaatt caaatacccc
212221 ccgtgaagta tcagatggag ctatcaataa gaaccctaga aataaatcta ctaaaaaacg
212281 tcaaagaaac agaggcaaat cttctaaaaa gaagaacaga tcgagaaaat aagagacatt
212341 atgaatttgg ttttttttac aatttacgca tacacaatat atacattcct actagctttt
212401 ttttcttcaa ttcgatagtt tagatgggtt tatatctaaa tatatatata tagtatttta
212461 tttcatattc aatctcctag tatacatgaa atatttaacg cttttttttg cccttgtttt
212521 tatttttttt cttttttgaa gctgcagagt taccattgtt attttgcaca gcattagctt
212581 tttgcttcgg ttctgtagca gttttcttag ccgcaggatc gctcttttcg acatctgtgt
212641 tgacaattaa ggtggctaaa ccaacaatgt cttggatgct cttacctttt atttttttac
212701 tcgattcttt tattttgtta tttttcttct tcgactgtgc tattttttca attttacctg
212761 gagttataga tacgcctcgt gggcctaatg cactaagtaa tcttgaaaca tctttactct
212821 tattagtagt aaatttatag ttcaaggata aatgcgagtt atgagttcta aaggacactt
212881 tggtgtctgt cttctgtgtt ggtggtttat acgatatgga gaagagcgtt tgagatggat
212941 tcacctcaaa aaggcgaaca ctgttcgtga tgtagttgtc aatgggtttc acagacatgt
213001 tttccagttc aattaggtct gttaatttgc tcgcggaggg aagctctttt atttgggtca
213061 atcgaagaca gcacaattga aacttttagc attgttctcg cgaaaatagt cagttcttaa
213121 cttttcaaga gtggtgcggc ttaccctgcc ttctgccata agtaaaaagt gacgcaaata
213181 gcggaactat tgtcattgtt attgacatta ataatctgta tttgtgctca tccggttcca
213241 tttactagta tgcagacgta tctttttcag ctggacgaat tgaggctttc attagctagt
213301 gtggtaatga caaactcttt gcactgagaa aatactgggg tgaggaaact tttctaccga
213361 attgcttcca catctatcaa agcatgatta tcaagtattc aaagatcaaa gcatgatgtt
213421 tgcaaataat aaatgttcag gcgtcattta atgttgataa tggtgtacgg gaagtgactt
213481 gtaaaaggta ggggaaaccg tcagtctatc actagtggtg tatctgatgg aagtgccctt
213541 ttatattttt tgccgtacac aggtaaagaa atgaaagtac taattatccc ccatactctt
213601 tgtttctctt gtgttgttta tgatcaatcc ttctaattta atcattcaat aactaaatat
213661 ttaaaaagat gtaattgccg caaaaaaaac tctcaattat ttactatttt gaaacagtct
213721 ctcagatagt atgcgccata ttggtgtgat gattcctgtg aaagcatttt tgggtttgtt
213781 taggtgcctt cttttcttta tttagcataa ccgccaatac ggaatgaaaa gtccgtttta
213841 atgtaccgct aataattcaa aatgcgtaaa agagttttca taaaaagggt atttgcgtca
213901 agcaggaaga aattttgaaa acaactaaca ggcaacttac aggcatatac tgactttagt
213961 aaacgtcttc cgctattcta agaaggagct gacttgaaca agatctttat tttaacggtg
214021 cgacaaaaac aaggaaagtt tacaagcgct agccgtcgaa gacgtcaatt gcactattac
214081 tcagtaccgt tttaatcctt accaacgtag aattactatt tgtgcagtag gagcctgtga
214141 aatgttcaag tcgaaaacaa gcactttaag ctatgatgaa accccgaact ccaacgaggg
214201 tgatcgcaat gcaacccctg taaatcccaa agaaaagagc caaacgaaac atttgaacat
214261 accaggcgac aggagccgac attcctctat tgcagattca aaaagaagct cttctagata
214321 tgatggaggc tactctgccg atataattcc tgctcaatta aggttcattg ataatataga
214381 ctacggcacg aggctgagaa aaacacttca cagaaactca gtggtttcaa atgggtacaa
214441 taaactcagt gagaatgacc gatggtattt cgacctattc gataggaaat atttcgaaaa
214501 ctatctcgaa gaacccacat atattaaaat atttaaaaaa aaggaaggat tagaacagtt
214561 tgatagaatg ttcttagctc aagagttgaa aattcccgac gtttacaaat ctacaaccta
214621 ccagggagaa cctgcagttg ctaattcaga gctattcaag aattcaatat gctgctgtac
214681 gttcagtcat gatggtaagt atatggttat tggttgtaaa gatggctctt tgcatctttg
214741 gaaagtcata aactcaccag ttaagagatc cgaaatggga cgctcagaaa agtcagtcag
214801 tgcctctaga gcaaactcac taaagattca aagacatttg gcgagcatta gttctcataa
214861 cggctccata tcaagtaatg atttgaagcc gagcgaccag tttgaaggac cttccaaaca
214921 attacattta tacgcaccgg ttttctattc tgatgtgttt agggttttta tggagcacgc
214981 tttagatatt ttggatgcaa actggtccaa aaatggattt ctaataacag catcaatgga
215041 caaaactgca aaactatggc accctgagag gaaatactca ttgaaaactt ttgttcaccc
215101 agattttgtt acatccgcaa tattttttcc caatgatgat cgtttcataa ttaccggatg
215161 cttagatcac aggtgtagac tgtggtctat actggacaat gaggtttctt atgcctttga
215221 ttgcaaagat ttgataacat ccctaacatt atctcctcct ggtggggaat atacaattat
215281 cggtacattc aatggataca tttatgtttt actgacacat ggattaaaat ttgtatcttc
215341 attccatgta tctgataaaa gcactcaagg aaccactaag aatagctttc atccatcttc
215401 cgaatatgga aaggtccaac acggccctcg aatcacgggt ttacaatgct tcttttctaa
215461 ggtggacaaa aatttaagat tgatagttac gacaaatgat tcaaaaattc aaatctttga
215521 tttaaatgaa aaaaaacctt tagagctttt taaaggattc caaagtggtt cctcacgtca
215581 tagaggccaa ttcctaatga tgaaaaatga acctgtagtt ttcacgggaa gtgatgatca
215641 ttggttttat acctggaaaa tgcagtcctt taatctttca gcagaaatga attgcactgc
215701 tccgcataga aagaaacggc tgagcggcag tatgagttta aaagggctgt tgagaattgt
215761 atctaataag agtacgaatg atgaatgttt gacagaaacg tcaaaccaaa gcagctcaca
215821 cacatttacc aactcatcaa aaaatgttct tcaaactcaa actgttggtt ctcaagctat
215881 caaaaacaat cattatatat catttcatgc ccataactcc cctgtcacat gtgcttccat
215941 tgctcccgac gttgcaatta aaaatttgtc cttgtcaaac gatttgattt tcgaactgac
216001 ttcacagtac ttcaaagaaa tgggccaaaa ttattcagaa tctaaggaaa catgtgataa
216061 caaacctaat cacccagtta cagaaacagg aggattcagc tcaaacctat cgaacgttgt
216121 gaataatgtt ggaaccattc taataacaac agacagtcaa ggtctaatcc gtgttttcag
216181 aactgatatc ttaccggaaa tacgaaaaaa aataatagaa aagttccatg aatacaattt
216241 attccacctc gaagctgctg gtaaaatcaa caaccacaac aatgacagca tattggaaaa
216301 tagaatggat gaaagaagtt ccacagagga taatgagttt agcacaaccc caccatctaa
216361 cacgcacaat agtaggccaa gccacgattt ttgtgagctg catcctaata atagcccggt
216421 gatttccggc atgccatcaa gagctagtgc tattttcaag aattcgatct ttaataaatc
216481 caatggaagt tttatatccc taaagtcaag aagtgaaagt acgagctcca cggtgtttgg
216541 accgcatgat attccgagag tttctaccac ttatccgaag ttgaaatgtg acgtctgcaa
216601 tggatctaat tttgaatgtg cttccaaaaa ccccattgct ggcggtgata gcggtttcac
216661 gtgtgctgat tgtggtacaa tcctcaataa tttcagatag agaatcagaa agtaagagga
216721 aaaactatct gttccaccgt ctttagatca taagcatgtc tgcaaataac atagtattat
216781 tatttatatc tgtagcgatc tttattattt ttcattactg acacattttc tcacagaacc
216841 atctacaacc cgaaagatgc cggaaacggt cttaggccga tggggtctat tagggcctac
216901 agagacgtca attgggctat aagaaaaatg aaatcgagga aagattttcc actctcaaat
216961 taagtagggc aaaaatatgc ttttgttcgc atgtggtgtt attccagttg cgagtcaggg
217021 tctgccgata tgctaaagga ggtcacgaaa acgaatctgg catttaatac ctcattaagt
217081 tacagcggaa tcggccttct gttgcggaaa aaaaaaaaaa aaagaaaacg aacattaagc
217141 accgctgaaa tttcaagctg tgactaagtc gtcaaatgat aaatactgca tatatataaa
217201 ctatgtgatt atatgcaaca ttaagatata ctttcttctt ccataatgcc cccactccag
217261 aactccatcc gaaatagttt tccttagatt gctatagcaa gtcagacaca agcacatctc
217321 atcgaattat atcgtaagca aatatgtcat ctgacaactc taaacaagat aaacaaattg
217381 aaaaaacagc cgcccagaag atatcgaagt ttggttcgtt tgtggctggt gggctagcag
217441 catgtatagc tgttacagtt actaatccga tcgaattgat taaaatcaga atgcagcttc
217501 aaggtgaaat gtcagcatca gctgcaaaag tttataaaaa tccaatccaa ggtatggcgg
217561 taattttcaa aaacgaaggt ataaaaggtc tgcaaaaagg gttaaatgct gcttatatct
217621 atcaaattgg gctaaatggt tccagattag ggttttatga gccaatcaga tcatcattaa
217681 atcagctttt cttcccagat caagagccac ataaggtaca gagcgtcgga gttaacgtct
217741 tttctggtgc cgcatctggt ataattggtg cagtcattgg ctctccatta ttcttggtga
217801 aaacaagact tcaatcatat tccgagttta taaaaattgg tgaacaaacg cactacaccg
217861 gtgtttggaa cgggttagta accattttta aaaccgaagg tgttaagggt ctattcagag
217921 gtattgatgc ggcaatttta aggacaggtg ctggttcctc tgttcaacta cctatctaca
217981 acacagcaaa gaacattttg gtcaaaaatg atctgatgaa agatggccca gcattacatt
218041 taactgctag tactatctct gggttaggtg ttgccgtcgt tatgaaccca tgggatgtca
218101 ttttgacaag aatctataat caaaaaggtg acttgtacaa gggacctata gattgtttgg
218161 tcaaaactgt tagaatcgaa ggtgtaaccg ctttgtataa gggttttgca gctcaagtgt
218221 tcagaatcgc acctcataca atcatgtgtt tgaccttcat ggaacagaca atgaaactag
218281 tttattcgat agagtcgaga gttttaggcc ataattaatt cccataacaa actccgaggt
218341 ttgaagtttc attcattggc caggacagtt ctactttact aatggtttca ttacaacctt
218401 tttcttcata ttatgtagca ttaaggataa tagagcattt tttatttcac attcatacac
218461 gatagtttta taaacgtaat tataaacata cagaacatta ttcacaattg tccagttcca
218521 agaattatat gctctcggat ctcggagttc ttatttataa aatgatcagt tacagtgtaa
218581 tcttgcttag aactttcttt ttctcaacct ttgttttttc ttttactttt gcttcttcga
218641 gttttttcag atagctgtta tacacaacca catctgctac taagaccaat attccaaaga
218701 acaagcacaa caaaagacga acatggaccg gaaagtttgt tgaagatccg gtccagtacc
218761 aaatggccac aacaaccgat atgacactta caagaacgtt gaaaacagtg gtaacttgtt
218821 ccttaatctg tttattaatt tgtgaaggcg tgagttcatc gtcttcttga agtgaaaaga
218881 cagacttgct tctcttgacc atactttgat attcaagttc ttgttcctga tatttcaaaa
218941 actctaattt tttcttgaaa tcctctgaat agtgtaaacc tctgacggcc ttgggcttga
219001 attcgaactc caaaggtttc aaaagttctt tgatagagca ttggagatca ctgtcttttc
219061 tatactcttt cacataaaaa agaagtgact gcataggtat tgcgtgtcgc ttcaggaaca
219121 aatcaatgtc ctcatcaatt ccttcgtttg atttcgcgct attcttgaac tttcgcagaa
219181 attcagttat tctatcattc agtttaattt cgaacattag agttctttta tgtgatgcca
219241 atcgtcaatt atcctatctt accttttctt catttctttc agcgttttca tgtgagattt
219301 gctttatttt cgcttcctcg tttctcattt taaatattca cacgtccgtc atgtctactt
219361 tgagtcagtt aaatacacaa gatttttgta aaactgagta tttcgtgaac aatataattg
219421 ttcggattca atcatagtta aagactatag tatgagatac acagaatatc ctaaaagttc
219481 ccctcgaggg tataggaaac ctcaaaatgg aatcggtctt tctacatgat aatattactc
219541 taacttcttt tcttctatac tttgccattc attaccctat cacgttatca atccttgcat
219601 ttcagcttcc attaagaccg ataactgttt cccaatctct atgtcatcat cttacaccgc
219661 tgtgataata ttctaggaag acgaatacta gccaatagat gatacaagga tttcatttcg
219721 acagaaacaa aaaaagcatg gaaaaacgaa tggagacaaa gaggaagtta aagaaagttc
219781 atttgtgacc tcatttactc agaagaattt cgtaaatcgg ttgttataga actgttttat
219841 tgtttaaaag agcttgttat agtaatctaa gtggaaatac actaacagta aatagggcgt
219901 gtggcgtagt cggtagcgcg ctcccttagc atgggagagg tctccggttc gattccggac
219961 tcgtccaatc tttttatact tattaataat ttttttcctg ccgttacttg cttttaaaat
220021 aactgccttt tatgaataca gagtataatt tttgatatac aaagaggttg actgtgataa
220081 tcaatactta atttgtggtt attggtacac atatacctac aaaagttacc aacaaactgt
220141 tcgactttta atgctacccg ccttccgagt gtttttgaag gggcggagag gagcggcaag
220201 aattagcatg gaaaaaagca taaaaagacg aaatgggtgg caatgtatta acttgttcga
220261 gaaacctagt ggactcaatt cattacaaca acaagttccc aagatcatcg attcataata
220321 gtcatgtccg ataaagttat taaccctcaa gttgcatggg ctcaaaggtc tagtactact
220381 gatccagaaa gaaattatgt cttaataact gtgtcaattg cagactgtga tgcccctgag
220441 ttaaccatta agccatcata catcgaatta aaggctcaat caaagcctca tgttggcgat
220501 gaaaatgtcc atcattatca attacacatt gatctataca aggaaattat acctgaaaaa
220561 acaatgcata aggttgctaa tggccagcac tactttttga aattgtataa aaaggattta
220621 gaatctgaat actggccacg tttgacaaag gaaaaggtga agtaccctta catcaaaact
220681 gatttcgata aatgggttga tgaagatgaa caagacgaag ttgaagctga aggtaatgat
220741 gccgctcaag gaatggattt cagccaaatg atgggaggtg ctggaggtgc tggaggtgct
220801 ggaggcatgg acttcagcca aatgatggga ggtgctggtg gcgctggttc tccagatatg
220861 gctcaattgc agcaattatt ggctcaaagc ggtggtaatt tggacatggg agatttcaaa
220921 gaaaacgatg aagaagatga agaagaggaa atagagccgg aagtgaaagc ttaaaaggag
220981 gagcaaatca acctggagtg ctagaatgag taacttagaa taaaagacga atatatgcac
221041 tttacacaac tctttacctg tttgttattg gctgcctcta tgtaattaaa tattatggaa
221101 ttaataaaaa tatttttatt cgtaactatc ttagatatat attgtacatt gtcaaaaaga
221161 cagtagtaag cagatagaag ctatattgga tgcaaaatag agaaaaaagc agaaatatta
221221 tgttgcaaat gtcaagtaat ggaactgtat gtgatattta aagaacaatt tctatatgct
221281 ggatgattat caggtgtaag caataagaaa gaaaacgaaa gtaactccca tccgtgggaa
221341 atttcaagaa aaacttagag tatcagcgat cgttttaacg aagggggatt cgtaaatttc
221401 attaatcgac caacgttggt tcttcctcgt tagcgtattt tccacaatct gttttcccac
221461 attagtttta taatcgctta accggtacca tctccaatca aacctggcaa tacgatgtga
221521 cgtagctctg ctacgctgtc ttgctgaagc gtttggagga gggtcaaatg gtaatctgtc
221581 ctcaaacaag ctgtatagta tgacacctaa ggcccacgtg tcgcttaaat ggccatcgta
221641 gggaactccc atcaggattt ctggtgagac ataatcctct gatccacatc ttgctgtaca
221701 catctcattg ttctcaattt ttttgcagag accaaaatct gctagctcaa tgaaattttg
221761 cttgcagtaa atgggtgagt ccctaaaact gttgatatca tcaaaactat atttcagtag
221821 tatattctct aattttaggt cccgatgaat aatactgttt tcgtgcaaat attttactgc
221881 cagtactact tccgtaaaaa tcctttgaat cagccacgct tctagtcttc cgttacgggc
221941 catgacggca gctaataagt ctcctgcagg acaataagac ataatcatat cacaaggcgg
222001 cagagctctt ggagttttta taatcaaatc gcataaaggt tttttgctag taacaaaaat
222061 tggattgttt atcccaagta gtttaactat acatgggtga tttagtgatt ttagcacctg
222121 caattcccta gtcagagaat tttccaaacg ggataaagtt tccttatatc gtaacgatgt
222181 attgatttgt tcaacatttg ataattcctc gggatatttg agtcgtttaa cggccacttg
222241 tttcagttta ggattgcttt ggtccatgag ttcatataaa agtacggtac taaaatttcc
222301 tgaaccaatg ggcctgacct ttttccataa taacgggcga tcccagtgat ctaaaagaaa
222361 tccctgaaat atatcatcgt cacacttttc ggtagaacta ctactttcgg gaaaataagg
222421 ttctttcgtg tagttatcac tatcaacaga atcatttact aaagcctctt cagtcactgt
222481 tggtaaggaa acaacccttt ggggggataa attagctggt gcaataagtt cagaaacaac
222541 tctttggttt ggttgtgtaa cagaaagcat atcatccagt aatcgtgcat gacttcgtct
222601 tttgggtata ttcaacgagg attgatctat aggtgacatt gacagattgc ctggggataa
222661 cggagtgtag gtcatcggtg taggtaatgc ttggacattt tcaaacgtcg gaatagatac
222721 agtcaaaggt gtactgcgag aatcaccagt ggtcccttca gtggatgcca tttttttatc
222781 ttcctcacca ttttcatcaa tcaatgcctt ttcgtgttga tcgccaatgg agtcgggaaa
222841 tccttcttgt ttcaaccgag gagtctttgg ttgtgaatat atactactat attcatccat
222901 tgtcggtata acctaacagc tgctgtgggt atggatgaat tcgaagcgta gatgtgatta
222961 ctatctcaaa atatacttgt ctaattgtgt aaaaaagaaa aaaaagataa agaacacacc
223021 ccgcgttgaa gattacaagt aaaaaacttt ctatgcttag gaataacgtt ccataagagg
223081 atggtgtgct cagccttctt agttcattta ctggaatgta tttaacttta cccttttcgt
223141 ctgctaatcc atcagtatgt gaaaaatgaa aatctaaaaa aaaaaaaggc tgccttattc
223201 tgtaacgcaa cgcgaaacat ctataaacca agtaagtagt ttctatgaaa tgggcaacag
223261 catcttggat gacgaagggt agcatttagt tacgtacgtt gagataatct acaaaaattg
223321 attacgtatt taaaattctt ctcgcttctc attattcttt cttagtcttc ctcttctttg
223381 tcatttgtga caagatatca ttatcgcttg gctctgcagt ggctttcttc ctcttggtgc
223441 ccccagctcg cttcttttgt ttaacctcaa acttgtctaa ctgttcctta cgcgatttag
223501 cacctaattt ctgcagcgta tcattttttt ctttatactc cttgtcttct aacaattcgc
223561 tctcactctt tgattccaac cactccataa gtttgatttc attaccatag ccttcatcat
223621 tttcgtatgg agtttccaag acaataggga taccctgcag gtattcagag tgcgcgatca
223681 ttctaaacac atctataccc aaataacctt gacccaagcg ttcatgcaaa tctctatttg
223741 ctcctaaagg agccttggaa tcatttaagt gaacagcact tagatatttg aaccctatta
223801 catcattgaa ctctttccaa aaattgttaa acgtttcagt ggtgctgata tcgtagcctg
223861 ctgcaaatgt atggcatgta tctatgcaaa cgccgattct tgatttatct tcaatcattc
223921 caataacctc cttcaaatct accagagaac ttcctactaa atttccagta ccagccatat
223981 tttctaatac aattttaaca aatttcgttt ccttaattgc tttgttcaaa tatgaggcta
224041 gttgttttaa ctgcaactga tggtctcctt tcaaagtaga acctggatgt aagttataca
224101 ggcctatccc taattgctca cacctgttca gatcgtccat gaatgactca taactctttt
224161 ctgccttttc cctatccgga ttagccaaat taataaagta ttggccatgc ggtaagacgt
224221 ccgtcaatgg gttataattg taagttgcac agtttttctt aaatttatct atttcctcct
224281 gtgtatactg cggagaaacc cactttcttg gagattttaa aaacatggca aacgaattac
224341 agccagtgtt aaatgcatta gttacactat tagaaattcc accggcacct gacatgtgcg
224401 caccaaattt gtatttcgag acagcagatc taacaaagct aggtgtcgaa ggcattacga
224461 tggttccgat atgccaaaag cttattaatg ttgcgttttg tgtttcttat tcggagtttg
224521 tcatcttata tttacaatga tttccaacat gtaaagaaat gaagaaaaag aaaccaggta
224581 agaatgaaaa attccacgtt caagttccca gaaaaactgg caaaaaaaga gaagtattag
224641 atgaaaaaag ttcgtgtata caaatatcta tgttacatat atgccaaggt gaaggaccaa
224701 aagaagaaag tggaaaaaga accccctcat cttcttccct ttgtgacttt attcttattt
224761 ttgttcaatt ttttattttc ttgtgctctt ttcgccgcag cagccagctg ttcctttgtc
224821 ttaggcacca cttggaagaa cccatctaac ctaccctgaa tgccagattt caagcctttt
224881 ttcaatcttg atataccaga tttaactctt tcttcactga atttcttatc atcacataaa
224941 tactcgataa gttccttctc ctttggtggc gaccatttca agtttatttc gttaccatct
225001 ataacttcag ggtcaagaaa cagcattctt gcttgtttgt aaggccagtc ttctgggatt
225061 ttccatttag tgttgtttga ctccccagat tcaataaact ccacgatttt ttcgatggat
225121 ccatgcgttt ttatcaattt taaggctgtc actggaccaa cacctctgat gctttcacag
225181 tagtcacaac caagcattat gcaaagatca acaaactgct ctattgtcaa gtcgagtcct
225241 ctcaaaacta attcagtatc tatttcgtga atcggttcct tcttggcctc tgaaaaagtc
225301 aaatgtctca acaagaaggg tgttctataa cagagtgtgt ccatatcttc acttgctgcg
225361 gcatacacct ttcccttctt tgccaactca gcacattgag cctcagcttc cgttggcgct
225421 attatatatg ggattcccat tagtcctagt aatttttggg cttcttcatt atgctctttt
225481 gagaccttca ccaatcttct ttcttgcttc atcttttcca attctgttgt tgcctctgcc
225541 agtttttttt ctgtttccac ccttcttgaa gaccgctttg tcaactcatg agatttcaaa
225601 tctggaggtt tgccgtcgaa gacataacaa ggcttgatac cgttatcaat cattctcagt
225661 gtcctataaa acatacccat caagtgtgac gttgtttcac cggcttcatt ggtcaactgc
225721 ccaccgtctt gctgtcttac agcaattaaa aactgatata gagacataga ggcatcgatg
225781 gcaacctttc tgccaaaaaa gctcttgata tcgcttttcc tgatagcaga gggaacatgt
225841 tccgatataa ttgcattcaa acctttaata cccatatttt ttcttccggt gtccgtttcc
225901 tatttctttc caatgtatgc tgtcaacgct tttcatcgat gtatataagg aagaatacct
225961 cattataata catcaaaacc ttcatttgcg cgatgttacg cgtcgcgttt cctataaaaa
226021 atacataagc tagtgaataa aagctttaaa cgcgttaggg ggatctgcaa ttaaagtaaa
226081 taaatgaaat aaatgaaata gatgaaaaac tggttacact aattataacg ttaataaaac
226141 tagttgataa tcaaaatatt gccatagcta agccaatagt acagcgttgg ctttctatca
226201 taacttacca gccgggtgcc caatcgggta tctgtcaccg aaagtcactg ttaacgaggt
226261 gtgattcagc cgggtactag tctagcattt tttttcgcct gtttttttcg tgaaaaacga
226321 aaagtggcaa gcaaacttat atcactttct acttctttcc ctgttctttt tgtttattgg
226381 caatggccac taccacatcc ccattaacga aagtcaccaa agtgtgtcat ttaatactac
226441 ggttagtgac agcattttgt ttagatctca actagagagg attatcaact gctaagccct
226501 ttacacgtta tctgtgatcc tgctgcacta ggaaacgttt caaatcacca tatttgcaat
226561 ttcacaagga tggacaaatt agtcgtgaat tattatgaat acaagcaccc tataattaat
226621 aaagacctgg ccattggagc ccatggaggc aaaaaatttc ccaccttggg tgcttggtat
226681 gatgtaatta atgagtacga atttcagacg cgttgcccta ttattttaaa gaattcgcat
226741 aggaacaaac attttacatt tgcctgtcat ttgaaaaact gtccatttaa agtcttgcta
226801 agctatgctg gcaatgctgc atcctcagaa acctcatctc cttctgcaaa taataatacc
226861 aaccctccgg gtactcctga tcatattcat catcatagca acaacatgaa caacgaggac
226921 aatgataata acaatggcag taataataag gttagcaatg acagtaaact tgacttcgtt
226981 actgatgatc ttgaatacca tctggcgaac actcatccgg acgacaccaa tgacaaagtg
227041 gagtcgagaa gcaatgaggt gaatgggaac aatgacgatg atgctgatgc caacaacatt
227101 tttaaacagc aaggtgttac tatcaagaac gacactgaag atgattcgat aaataaggcc
227161 tctattgacc ggggattgga cgacgagagc ggtcctactc atggtaatga cagcggtaac
227221 caccgtcaca acgaggagga tgacgtccat acccaaatga cgaaaaacta ttctgacgta
227281 gtgaacgatg aagacatcaa cgttgccatt gccaatgccg tcgcaaatgt agattctcaa
227341 tcaaacaata agcacgatgg aaaagacgat gatgccacta acaacaatga tggccaagat
227401 aataatacta ataacgatca caacaataac agcaatatca ataacaacaa tgtcggtagc
227461 cacggcattt cctcccactc accatcctcc atacgagaca cgtctatgaa tttagacgtc
227521 ttcaattctg ctaccgatga tataccgggc ccatttgtcg ttaccaaaat tgagccctat
227581 catagtcacc cactagaaga taacttgtca ctgggtaaat ttatcctaac taagattcca
227641 aagattttac aaaacgattt aaagtttgat caaatactag aaagctctta caataattct
227701 aaccatacag tgagtaaatt taaagtttct cattacgtgg aggagtccgg tcttttagac
227761 attttaatgc aaagatatgg attaaccgcc gaagatttcg aaaaaaggtt actttcccaa
227821 atagccagac gtataacgac gtataaagca agatttgttt tgaaaaagaa aaaaatgggc
227881 gagtataatg atttacaacc ttcttcatct tccaataaca acaataacaa cgatggtgag
227941 ctttctggca cgaacttgag aagtaactct atcgactacg ccaaacatca ggaaatatca
228001 agtgcgggta cctcatcgaa cacaaccaaa aatgtgaata ataacaagaa tgacagtaat
228061 gacgataata acggcaacaa taataatgac gcctcaaatt taatggaaag tgtgctagat
228121 aaaacctcta gtcaccggta tcaacccaag aagatgccaa gcgtcaataa atggagcaag
228181 ccagatcaaa taactcattc agacgtgtcc atggttggcc tagatgaatc aaacgatggc
228241 ggtaatgaaa atgtccaccc aaccttggct gaagtagacg ctcaagaagc tcgtgaaact
228301 gctcagttag ccatagacaa gatcaattct tataagaggt ccattgatga caagaatggt
228361 gatggccata acaattcgtc gagaaacgtg gtagatgaaa acttgatcaa cgatatggat
228421 tcagaagatg ctcacaagtc caaaagacag catttgtcag atatcacact ggaagagaga
228481 aatgaagacg acaaactacc acatgaagtg gcggaacagt taaggttact gtcatcgcat
228541 ttgaaagagg tagagaatct acaccagaat aatgatgatg acgtagacga tgtaatggtg
228601 gacgtggatg tagaatcgca gtataataag aacacaactc atcataataa ccatcatagc
228661 caacctcatc acgatgaaga agatgttgct ggactaatag ggaaagccga tgatgaagaa
228721 gacctttctg atgaaaacat tcaaccagaa ttaagaggtc aatagatacc cagttgagaa
228781 gacgagctat ttttctcatg tttcttttgt ttattcactt ttctatactt tttcttttct
228841 attgaaatat atattatatc ttatgtatgt ttttttgtat tataaacaag caaatttcgt
228901 cttgccattt accttctgat attaatcaca tgtatatctc aattcaagtt tttgttaaga
228961 taatcagcga aaagcggacc gatcctatct tgatctatat ctcttagttt gttgaagtta
229021 atgaattgcc ttttcaatct ctgcaattgc gccaacgtaa cgacgttacc aatgggcaag
229081 tctacgaaga agcaaccatc atcattgata tcggtaatcc cttcggaaac aatgactctt
229141 gttccgttac ttaccccgcc aatagaagtc aggcttttga tgtggttcat tatggttttt
229201 attatcttac tagtttcgat gtcgagaacc tggatgaaat tggactgaga cgcaggcttt
229261 agtaccgtgg ctgagttcgg tttttgtaag cccttactca acggatcatt gtgtccactg
229321 tttttagccg atttggaagt ttgaaagact actttacaaa tatcgtcgat gtagtcagtt
229381 atgttgtcct gaggagtaag aatagcaaag agtggagagt cccatcggtt gcttgagtta
229441 ggctcttcgt atcgttgaat caattgattc aataactcgg gttcccaagg gttcgggttt
229501 gaagtcttat tccactcgaa tatagtctct ggtggacaca gtgtttgaat tacacaaaat
229561 gtggtggaca aatttttcac ctcgcagtga agttgatacc ggaaaccctt gatataattc
229621 aacgagtcta caatgactat cttgttttta gatagatctc ttttcactgc ggagatgatc
229681 tccgacctca attttctttc atcttgggaa gttatataat ctgaatgttt tatgcctaaa
229741 gattcatctg aatgataggt tatggaatat ttacttaatg atggggttgc atcgatcttg
229801 gactgtagta gttgtaccaa atgtttagca agcgttgtct taccactaca tgggtatccc
229861 gtaaaaagca ccagtggcat cttcttacta aattgcctgt ttagtttttt caaaagtttt
229921 acaaggtccc tttaccctca ttctgatacg ttattgttca agtttcacct gttcatcaag
229981 tattcttcat ttctttttcc atcgcgatga cgatgacaaa acggcaaaaa gtcaaagaaa
230041 aagaaaaaaa aagatttttt ttccatcata tgcagagaga atatgtccaa gccaagcgca
230101 gtgtgcatgt atgctgtttt tagcatatcg ggtgtgcgaa aggaatgaca taatgatttg
230161 caactaatat ttccttatat aaatatgctt ctggatatga gtctcatgaa acaagttcag
230221 taattgcttg ttttaccctt acttttttct tggttatgac ttgtgtacat aataaattgc
230281 ctattttccc aaattgtgtc ctttttcctt tccggttggt atgagatatt tcttttcaaa
230341 aatcaaaaga aaacaacaaa gggttgatat tatgtaatgc aatacctaga atcgggaaaa
230401 acttgtttgt cgtaccaaga gaggcagcac tggcgtgcct tgatttaata taactcctga
230461 gatagtgggg gttacatgag ttgtacagca taagactccc tctccccagt tctgttcgta
230521 tatgtcgggc ttgcttgcga aagcaagggg ttcaataaac agaaaacaga gtttttggat
230581 aaagtttaaa caacggaaac agagcaacaa tgaaggagag aataagtatc aattgtgtaa
230641 ttctgtatac cgtagtgcac agtacgctgt gcgcaactct tgcctaaaaa atctagttat
230701 caagcggggt gaatatgcta caatgcctct tttacgttgt actctatcaa gggatgatag
230761 cagtggcaca tattgattga tacgactttt cgccgcgcgg taggcgaaaa gcaaagaaaa
230821 ctacagtaat atccagaaat agatgcattt tatgtgcgaa ataaaactca tgctgaaaaa
230881 aatagtaata attaataggg taacgaatag aatgcaaacc ttatcacgtg aaagagagaa
230941 caatcataaa tgatttagtg cgtaggtcca gatttgcgaa acactgcgga aggcgagaaa
231001 agaattcgaa tatgaagtag gtagaagcag aggtagggcc gctatttaaa gatatacttt
231061 ttctgtacgg gccggtgact tcgcagtagt gatgtactat gagatcacta ttttgccgga
231121 aactgtaggc aaaaaccgtt tatgtctttt tttcacctta cgggataacc tctgctgaga
231181 atttccaaaa ctaggcatgg atgattgccg gaatttgaaa cccgggcccc ggaggttgat
231241 cgcacggcaa atacataaga accttctccg caatacgggc tttcctcaat tttcttggcc
231301 aaaaagcgag tcggccccga gctacaaatc gggaacaacg gaggaataga gcgacaagtt
231361 gattcggtcg tgcagcccgg aaaaaaaagg ctgtcctgcg ggctttattc actccaatgc
231421 cgctgagagg aacacgcgtt tcgtgggctt tggaccacta ccccggcgtt cagagaaacc
231481 ccccggggca ggggtccgaa gtctaaaagt ttaatccgga agtagcgacg ggggggaagc
231541 ccgccgcgca cagatggcca gcacaacgga gcggggccga ggcggcaaac gaggttaagc
231601 ccgctgaacc tgaaaaaaaa aacgaaaatt ttctttcatc aaggactaaa gttttcttat
231661 gttacggatc ttgcacgcgg taagcaatgg ccgtagcctt ttcacagttg cttccaagtg
231721 tcatgtatcg attttgcaga ttgttctaaa agtaaatgga ttgctatttt ctttccgaga
231781 ctactctaaa aaaatttatt gagtatgaga tcgtttttag ataaattata tatattgtaa
231841 agctattaac taatctccta tatcaatttc ttcttgctta accccgtgtg gttgtttagg
231901 tccatctcct ttttcctttt aattttttta cctttattaa ttccttcacc tctctaaacc
231961 ccagttttat atcgtatatg ctatctacag gtccacttta cacttaataa tataaaaata
232021 ctactataaa ggaaccagaa aaataaaaaa gggtcattat ttatttgagc agatcattat
232081 caaacgcata ggaagagaaa aaacacagtt ttattttttt tccacacata tttattggtc
232141 tcctagtaca tcaaagagca ttttaatggg ttgctgattt gttttaccta cattttctag
232201 tacaaaaaaa aaacaaaaaa agaatcatga ccgcaaagac ttttctacta caggcctccg
232261 ctagtcgccc tcgtagtaac cattttaaaa atgagcataa taatattcca ttggcgcctg
232321 taccgatcgc cccaaatacc aaccatcata acaatagttc gctggaattc gaaaacgatg
232381 gcagtaaaaa gaagaagaag tctagcttgg tggttagaac ttcaaaacat tgggttttgc
232441 ccccaagacc aagacctggt agaagatcat cttctcacaa cactctacct gccaacaaca
232501 ccaataatat tttaaatgtt ggccctaaca gcaggaacag tagtaataat aataataata
232561 ataacatcat ttcgaatagg aaacaagctt ccaaagaaaa gaggaaaata ccaagacata
232621 tccagacaat cgatgaaaag ctaataaacg actcgaatta cctcgcattt ttgaagttcg
232681 atgacttgga aaatgaaaag tttcattctt ctgcctcctc catttcatct ccatcttatt
232741 catctccatc tttttcaagt tatagaaata gaaaaaaatc agaattcatg gacgatgaaa
232801 gctgcaccga tgtggaaacc attgctgctc acaacagtct gctaacaaaa aaccatcata
232861 tagattcttc ttcaaatgtt cacgcaccac ccacgaaaaa atcaaagttg aacgactttg
232921 atttattgtc cttatcttcc acatcttcat cggccactcc ggtcccacag ttgacaaaag
232981 atttgaacat gaacctaaat tttcataaga tccctcataa ggcttcattc cctgattctc
233041 cagcagattt ctctccagca gattcagtct cgttgattag aaaccactcc ttgcctacta
233101 atttgcaagt taaggacaaa attgaggatt tgaacgagat taaattcttt aacgatttcg
233161 agaaacttga gtttttcaat aagtatgcca aagtcaacac gaataacgac gttaacgaaa
233221 ataatgatct ctggaattct tacttacagt ctatggacga tacaacaggt aagaacagtg
233281 gcaattacca acaagtggac aatgacgata atatgtcttt attgaatctg ccaattttgg
233341 aggaaaccgt atcttcaggg caagatgata aggttgagcc agatgaagaa gacatttgga
233401 attatttacc aagttcaagt tcacaacaag aagattcatc acgtgctttg aaaaaaaata
233461 ctaattctga gaaggcgaac atccaagcaa agaacgatga aacctatctg tttcttcagg
233521 atcaggatga aagcgctgat tcgcatcacc atgacgagtt aggttcagaa atcactttgg
233581 ctgacaataa gttttcttat ttgcccccaa ctctagaaga gttgatggaa gagcaggact
233641 gtaacaatgg cagatctttt aaaaatttca tgttttccaa cgataccggt attgacggta
233701 gtgccggtac tgatgacgac tacaccaaag ttctgaaatc caaaaaaatt tctacgtcga
233761 agtcgaacgc taacctttat gacttaaacg ataacaacaa tgatgcaact gccaccaatg
233821 aacttgatca aagcagtttc atcgacgacc ttgacgaaga tgtcgatttt ttaaaggtac
233881 aagtattttg aaataggcat gttgcaataa aacgaaaaca actaaaaatc acgaaaacaa
233941 aatgatatta tacaataaaa aattcttatt atgggtaatg atagtattct tcgcctgctt
234001 aggcgtcctt ttccttcaac aacaaaaatt ccaaaaaaaa aaagtaaaaa aacaaaactt
234061 tgattgtttt ttaatgatgt taatgatttt ttttttcttt ctttatcata aaaaaaaagt
234121 taaaatgaaa aacaaatatg ggtctggaag gccattattt tttttttatt tatataccgt
234181 ttctggtact tagttattta ttctcataca tacactatat tcaaattacc taagagcatt
234241 ttcacatatc cgtttacttt catttttttt ttttttgctt cctttttaca tatcttccgt
234301 atatcacatc acgtttacgc gtatggtgaa acacgtcaag agaaaaatga taaaatcaaa
234361 ttttgattta catcaggctc cacaggacag ggaaatctat ctagtgaggc gataactgta
234421 gttcgatgta ctcatttgaa ctggacaaat tgaaaattga gctgaaaaca tgggagcatg
234481 atttcattga taaaaataaa agggaaccca caagggatga catcaagagc ctgcggactg
234541 ttcggcagat gtataaacaa tattccacac tgaagaagaa acaatctttg caacgacaaa
234601 aagttgacac tcaagagtcg gttgaactcc cggcacataa aaaagaccac gacgaagtcg
234661 tagagatagg ccctactccc caagtttacg gtaaggcgat tagtatcttt gacatgaatt
234721 tgtcgcctat aaagcctata tacatgacat tcacaaataa tattgatgtt aacaatgata
234781 actccaagac aatttctaat gaatcttctc cacgaaaaac tattctccta aaatcgtcgc
234841 ctgcagatcg tacgttagtg gcggaaccaa tatccagtgt gaaacgccaa ttaaactttc
234901 aaatgctaaa cgcttcttct acacgtactc cgacttcatc accatgcaag aatcgcaatg
234961 ggaagttggt agaaatcaag aaatgtagtc caactattaa tcctccacta gaatctggca
235021 aaccatcggg gtattatgga cctaattccc cgctaaaatt ggatgaagaa aacattcacc
235081 taaacatctc acttaattca agcactaaac gccggcttca aatagcatat ccatctttac
235141 agaagactcc ctcaaaggat caagcggata tttcaacttc atttagtccg tctccactca
235201 ttagaagacc actgacgaaa tccctgatag aattggccag ggaacatact gaaattgtaa
235261 aagaatttgg tgtcttacag gaagaagata ttgaagagga agaggaagga gaagaaggcg
235321 agaatggtta cgatgagaaa aaccacgaag acgactttgg gctagaagat gaactaatta
235381 gaccaaaagt tgtgaaggac atatttcaag aggatgatga taatgatgat agccaagcaa
235441 gggaagatac cttcataaga aagagaccca aaagaagaaa ggttatcaga agattacgag
235501 acaatgatcc agaaaccgag accgcaggtt ttgagagaga tgtccataag gagctggtga
235561 aactcaaaag aaggaaagtg gcagaatttt tgggatccac ctcacaaatc tctgatactg
235621 aatttgaaca tgatccggag gcaagcagcg gcgttgtaag ctcagagcaa aagcctacgg
235681 ctaagcgaaa gggtagaaag aagtataatc tagtgagcaa taacttcaga agactaaaac
235741 tgccaaagaa aaaccgattc tctaatggac gatggggaag aaggtgagcg tgatggcgta
235801 aataatacaa acatttgtaa tttatagaaa cctattaagt attcagttag attccttcag
235861 ctgcatgacg tatagtttat atggacatca tacgtatttt tatcaatata gagactagca
235921 tgtttttaca ctttttattt ttgttgttca attaggggcc tcgtccatat atgtatatat
235981 attacataat ctgcaatcat caattagggg aggaataatc ggcagaggta taaatacaaa
236041 atttaaaaca attcaagtga atgaaaaggt gaaccaacaa acagaatatt accacgtatc
236101 aaggaaaaac taataatagt atattggcgc atttagcagg atgttctgga aaaaggatcc
236161 caccgtcagt tgggaaagaa aaaatatcaa tgacattgat tttagtcgtt ttaatgtggc
236221 cataattggt ggcacaggtg gacttggacg tgcaataagt agagagctgg cccaaagaaa
236281 tgccagggtt actgttgtcg ggcaaacttt tagggacgag gacctaaaag ataaaattaa
236341 ctttgtcaag gctgatttaa gtttagtgtc agaatgcaag cgtatatctc atagtgatga
236401 aattccctac gaggagttaa cacatctgat tttcactacg ggtatttttg catcacgcca
236461 gagacaagct acaagtgagg gtttggaaaa agacatggca gtgagctatt tgagtagata
236521 cattatcttc catgatgtgg cgaagcgatt aggaattagt aggacaaaaa aagacgattt
236581 gccaaaagtt ttcatagcag ggtttccagg aaatggtcag gtgggagacc cagatgactt
236641 gaattctgat gaaaagaagt atagtgccta cgctacacat atgaacactg tggcagccaa
236701 tgaaagtctg gtcatagacg ctaaagacag atacacgaat atagatactt tcggtttgaa
236761 ccctgggctg atcaaaacga acattcgtaa taatcttctt ggcagtgaca cctacctcag
236821 ccgcattaca gaatggataa tcagctggac ctgtcaaagc gcagagacgt atgcgaaaac
236881 aatatgcacc ctgattgcga gccccgctat cgaatcacgc agtggtacaa tgttcagcaa
236941 caaaggcgat gctattttac cttcgcctgg tttgaccaaa gatgttgttg agaagtttat
237001 ggaaaattcg gaacttctag ttgaaaaggc cttgcgtaat caaagtcctt tcacttccag
237061 taacgaatga cttgctgtaa ctaattggtt tatatttaaa tatttcactt tttaaagggc
237121 gtttgcatgc gaccatcgtc gatgattcat attgttcgga tgcggaagat ggcttccatg
237181 agttttgcac gccgtctcat gtgattgttg gagtcatagc tcgcatatct tcctattgtc
237241 agatgtaata tcgacggaaa tggcatcttg gagtatggaa gcactattct gctttgctcc
237301 aatatttagg atgccgcatt tttcatattt ttttttacat ttttcgctta cgtatataaa
237361 ttgctagcaa gtattcgctc tctctgtctt ggttatctaa ttgctaaccg tcgcaattga
237421 aaagaaaaaa aaaatacaga atagacgata gcggattgaa cgatagcata ctattgagtg
237481 cgttttccct tctcatttga aaattactat ccgtttttca ctgccgaaag acttgatgtt
237541 gaggacgagg cttactaatt gcagtctatg gaggccctac tacacgtcat cgcttagtag
237601 agtaccaaga gcacctccag ataaagtctt ggggttatct gaacacttca aaaaggtaaa
237661 aaatgttaac aaaattgacc tgaccgtagg aatatataaa gatggttggg gcaaagtgac
237721 gacgtttccc tccgttgcaa aagctcaaaa attgattgaa tctcatttag agttgaataa
237781 gaatctttca tatttaccaa taacaggttc caaagaattt caggaaaacg ttatgaaatt
237841 tttgttcaag gaatcatgtc cgcagtttgg gccattttat ttagcccatg atagaatcag
237901 ctttgttcag actttgagtg gtacaggcgc cctagctgta gcagctaaat tcttggcatt
237961 atttatttca agagatattt ggatacctga cccatcatgg gcaaatcata agaacatttt
238021 tcagaacaat ggttttgaaa atatttaccg gtattcctat tataaggacg gtcagataga
238081 catcgacgga tggattgagc aattgaaaac ctttgcatat aacaaccagc aagaaaacaa
238141 taagaaccca ccttgcataa tcttgcatgc gtgttgtcac aaccctacag gtctcgaccc
238201 aactaaagag caatgggaaa agattataga tactatatat gagctaaaaa tggtacccat
238261 tgttgatatg gcttatcagg gtttagagtc tggtaactta ctaaaggacg catatttatt
238321 gaggctatgt ctcaatgtaa ataaatatcc aaattggagt aacggtatct ttctttgtca
238381 atcttttgcc aagaacatgg gcctttatgg tgaacgagtt ggttccttaa gcgttatcac
238441 gccggcaact gcgaacaatg gaaagttcaa ccctctacaa cagaaaaact cattgcagca
238501 aaatattgac tcccaattaa aaaagattgt cagaggtatg tattcttctc caccaggata
238561 cggttctcgt gtggtaaatg tagtattatc agatttcaaa ttgaaacagc aatggttcaa
238621 ggatgttgat ttcatggttc agagattgca tcacgtcaga caggagatgt ttgaccgtct
238681 agggtggccg gatcttgtaa atttcgcaca acagcacggt atgttttact atacaaggtt
238741 tagtccaaag caagtcgaaa tattgagaaa caattacttc gtctatttaa caggtgatgg
238801 tagattgtcg cttagcggag tcaatgattc gaacgttgat tacttatgtg aatctcttga
238861 agcagtctcg aaaatggaca aactcgcata attttttcac cttacagttc acctttgtct
238921 ttattttttt attacttttc ccttctcatt ttgccacaca ataatttata gaatataata
238981 attttttgta ataattaata aacctttttt ttatctactc tatatacact tttcagataa
239041 ctagattgga ttaattcgtg atcgaactag ttattaaatt ttaaatgaaa agaaagctag
239101 cgctagccaa ctattttaat tacggtggca gtgcatcata tccttacatt tcattttagg
239161 tttcctatgt tttcttcttt caaatcattt cctgccaaaa atttttttca gtttcctacc
239221 gaatttactg tgaccgtgac ggtcatgcga cttatctttt atagctgcat catcgttatg
239281 aagcttgtgt atctctccat ttttatcaat gatagtcacc ggaacgctta atggtaaggc
239341 tgtaggcagg tcaggatttg atgactccaa agtggctgtt ccaccagata tgttcctatt
239401 tgacaattgg cttttatttc cgaataatga aaaccggtgg ccttctgtac cagcttcgct
239461 tacgtcatta gtgttcatgg atgatgcagt gtaaggggaa gaatcatcgt tgttgcagct
239521 ctttttattt gctaatattg gcatatcgtt ttcgttggtc ttatttttga agttcgtcat
239581 gggattaact atctctgttt cgttcgtggt atgagtagaa tgacttgttc tccttttcag
239641 cggagagggc aaaccaaaag tccatgattt tcttgagaca tgacctcctt tttccttctt
239701 ttcttccaca tccaggttct ctgctgctgt ggctgtagca ttctttgtga taagtggctc
239761 tctcaaagac atgcttctaa atcctaggtt atccttcgca ggtctttcct tctcaaaact
239821 agacttcctg gcggggggtt ctttggggta gagtgcacta ttatttttat caatgtatag
239881 agggacatga tcaggcaatc gtctcgatgt tgtgctcgcc tgaggagctt ttggaaaaca
239941 cttggacgcc tcgtgtgaag ccaagttgcc agatgatgga ggatttgatg gcttcttgct
240001 atgatatgga ggggatgaag atgagtcaga agctggatat actatattat gcgaaagagt
240061 agcctcattt gaactaccac gtagagttct taggcacgaa cgattggtga tttttctttt
240121 atcgtcgaga cgcttgggag acatcacggg tatttgatga gaactagatt gatcgtattt
240181 ctgttttgaa atactcgtcg gagggccatg gctgttcgtt ttcgtattgg aagcagtttt
240241 ccctgtagag gaatcaatat ttggagacgt ttctatcgaa taaatggacg aggaagtact
240301 tgatggaacg gctgattgtt tcaaatcaga tctaagttgt ggttgtagtg agcttttcaa
240361 aaggtcaggt gcaactcttg tggtatccgt ggaggacttg gagttcacgt tttcggaatc
240421 taggctgaaa gtgtctgaac ttgtgttagt gaggtaagga ttagcaccac gtaaatactt
240481 ggccatgttt gttccggact gactaacttc tgcattttca gaattttgtt ccttcttttt
240541 attatcttct gtctcggtag aatattctga agggtgtttt aatgaaggca cgtcagatat
240601 atcttgttct atttgaaccg gatctctcat tatcacgtca taagaatcat gatattcatc
240661 atcatcgtca tcatcatcgt catcatcatc gtcaacattt tcatcatcgt caacattttc
240721 atccttgtca tcatcgttaa catcatcgtc cttgtcatca tcatcgtcat tatcattgtc
240781 tttgtcatca tcatcgtcct tgtcattgtt gggtccatta tttttgtcca taacactacc
240841 agtctcatcc tccagtttaa cgttctcgat cccagaagtg ctagggaatt tttcagaact
240901 ttccggttca ttatcggaaa gcgcctcttc ttgatcttct ttttggacta aaaagcaatt
240961 tgtatcgacg aggcctgact tttttccctt tgtacgttct tcctgttttt cactatcatc
241021 atcttgcgga atttttagtc caacctgatt tccgcctatt tcagactcca cacttgtctt
241081 tgcagtagcg cgaagatcag ttgccgagcc ttctatataa ttataatcgg ataattcgct
241141 gccagtgaga ctgtttgaat ctgcaatgca cctcacttcg ttatctgaat tcatgtggaa
241201 gttagaattg tttaaagagc cgagaagaat aggatctact aaatttcctt cggcatcaac
241261 agaatcgata ttctctgcat tttcaatatt ctgagtttga ttggagagag ttgatggctc
241321 tttctccacg tcttccggag gtacataggc aggcttaggt tctgataaag taggttgacg
241381 aatcgtgatc gatttgacct cggatgctac ttcctgtcct ttgtgaaagt gttgttttct
241441 tttgctttca attagtttta attcttgggc ttcaaggtcg gcattctcct taactatatt
241501 tagctctctt ttcaataact ccattctccg ttcttcatct agcttaactt ttcgcaattc
241561 caaaattaag ctttgttccc tttcttcttc gttcaatttt gctatttcga tatttgatat
241621 tttttcctcc aagctatgaa cctctttaag caatgtttca atttcttcct ttttctcacg
241681 tccactgaga ccacttttat cttttttggg tatgctacga tcgagaacgc tgggttcaat
241741 aaaagagttt tcgtcatcgg atataatcat gggtttaaat tctaaaggat catgaagatc
241801 ctcttgcagt tcttgttccg tttcctcgtt catagttgtt ggtattaatg gaacattgtt
241861 atgccgttgc tttaatgatg tagtatgcat tttagataat actttgccat gataatcgtt
241921 ttttgattta ccgccgcttt cacttttttt ctcttgtgat cctgctttct tagtagtttt
241981 attcctatgc attagactag ttttgttgtt tcgagtaggc aaagaatatg ctctaccacc
242041 tcgttggttt gagcggttgc tcagactgta tctaggaggc tctacttcca cgggtacttc
242101 cacagccatt aaccccctag ggcctggtat gtattttttt atcgtcctta ttgtgctgcc
242161 tgagttccca agtgatgtgg tccttgattt actattctga ccagtcgaac ttgaaatgtt
242221 taaaaccttc gatgactgct tgcctccaaa ttctcgaaac gtggtttctg catcctcgtg
242281 agccctgtgt tgccttctcc ccgccgaatt attagaggta ttcttatgtc cttggtttgg
242341 caaactcgac gtgcgcttag agtattggcg aacgttacca ttcattaaga gcatccttga
242401 gttagtccta gaattcgaga gcattgtata cctattaatc cctgcgattg acgtagttcg
242461 agaggtaaaa ctctgattgt attgcggtat tttactcttg tcaacggtcc tcccattata
242521 actgagcgca tttccaattg ctgctgctgc tgctaaggca tctggactac tttcttggat
242581 catcccgcta tttccaatgc tcccactatt tgttgatact tgcctctttc agagctatct
242641 gccttatgtt gattattagg gttaataaat gctatttcct cccgcaataa ttgtgtaatt
242701 tgaacgaaga atatgaagaa gatggaatgg cgattttcac tctaaatttt aaaaattgcc
242761 tctttacaat agcgaatttc ctaacccttt tttttttttg ttgattgcct attgctcgtt
242821 cacttcccat ttattttctc tcgaatttca ccaaaagttg atgtggataa tcaatcatcg
242881 ggcctattcc tgcgggtaaa acgcagggcc caactcagga tagggtttaa tattatttta
242941 gaggacttac aagaaggaag ttatatggtt taaaaattgt aacaaagtta gaacacattt
243001 atttagcagg tctaatttag ggctgcaact atctttttgg ttattcatat aaaatataat
243061 tttttattta tatagagaat acaagtggaa tcatctttaa cgccagcttg tagtgcgcat
243121 tgcagaataa tggaagttca aaaattaaaa gcgaaggaga agtgatagta gaaagacgga
243181 tgggaggctg ggggacgaag agaaagtaaa agggttaatt tattcgacgg taacagattt
243241 agccaagttt cttggaaaat caacatcaat ccctttatta acagccaacc aatatgacat
243301 tagttgtaat ggaataatat taattagacc ttgtaaacaa tcaacagttt gtggaacttc
243361 taaggtttgc aggtcgattg atttagattt ttgcgcccac acttcatcat tttcgttaca
243421 aataataatt ggatggccct ttcttgcagt aacttgctca atagaggaaa ctactttagg
243481 gaatagagag tctctggtac caaaagcaat gattggcaag ttttcgtcca ccaaggccaa
243541 gacaccgtgc ttcaactcac ctgccaaaac accttcagaa tgcatataag aaatttcttt
243601 gatcttcaaa gcaccttcca gagcagcagc aaattggtaa cctctaccca ataacaatag
243661 agatttttga tcctttaatt cagtcgcaca gagctttttt attcttggtt ccagctttaa
243721 tacctgctta atttggcccg ggattaactt caagccttga atgatttcaa ttcttctgtc
243781 tattttcgat acacggtcat ctgacagcga tagagcaaac atcactaagg caatatactg
243841 ggaagtataa gcttttgtag aggcaacacc aatttcagga ccagcgttaa tatgaacacc
243901 acagtgggtg acacgagaga tagaagaacc aacactgtta acaattccga cagttaaggc
243961 tcctctttct aaacaataat ttagagccag catggtatcc gcagtttcac cactttgtga
244021 aacaaacacg catacatcgt ctctgaagac agggcatttt ctgtccagaa agtcagacgc
244081 taattccaca ctaactggga tatctgataa ttcttcgaag atagcacgag tagccaaaca
244141 tgaatgataa gaagtaccgc atgcgatcat gatcagtctc cgtgctcttc tgacaactgg
244201 taaccatgcc tttaaaccac ccaatatcac tttattattt tcatagtcga ttctacctct
244261 catagtattg aaagtagatt ctggttgctc atagatttcc ttttgcataa aatggtcgta
244321 agggcccttc atgatctgag ctaactccat ctctaaagtt tgaatggacc ttgtcattga
244381 tgcgcctact tctcttctag atctatgaat atgtaactca ccatcgtaaa tatgagccaa
244441 atcgtcatct tctaaaaata gcaccttctt ggtatgttta acaacagatg ccgcatccga
244501 agaaacaaaa aattccaccg gtgttggaga tccatcttct gataggaaag ccctggattg
244561 agaatgtctc aagttaaatt cattggcggc aattggtagt aaattggcat tttgggaacc
244621 agcttcaaat tcacgagctt tctttgggcc caagccaaat gatttgttgt tagatttcaa
244681 tggaatttcc ggttgaccag cgttttcttc gggaaattcc acatccacga agtcgacttt
244741 tagttttttt tcagatttga caccaatcag taaaggggac ccttttctag tggcgataac
244801 ctcattagga tagtgacaag atttacataa taacccgtat gaaccttcta gttctaaaag
244861 aactagcttg gttaattcgt ggaaatctaa gtcatgccca ttttgtaaat ttgtattgta
244921 taaatgcaaa tatagtttag caatacactc ggtatcggta tcactttcga atttataacc
244981 tttgttaatt aaaagagtct tcagttctct aaaatttgtg atgataccat tatgaacgac
245041 cacaaattgg tcttctgggt cagatctttg agggtgacag ttaacttgtt ctggtcgacc
245101 gtgagtagcc catctagtat gcgcaatacc acaatgagag acaaaagtaa cgtctctgtt
245161 cggattttgc ttagtaatct cctctttcaa agcactcact ttaccgattt gcttatagat
245221 gaaagtagaa tcagcttcgt caccatcgat agcaataccg gtggaatcat agcctctata
245281 ttctaatctt tgtaaaccat ccactaaggt gtcgataatt tctcctctgg atctttccac
245341 tagataattg cagtaaccaa agataccaca cattttttta taaaagttgc tgttgatttg
245401 ctcgagaact tattgcttat ttggccctga taactatata agaaaagaaa tacagttatt
245461 ccttgtttat gctggctttt tgtccacttt ttctcaacta tataactatg atgttggaaa
245521 ggacaccggt tctgtaactt tgcagtgaaa ataagtgtga tggatgactg agaatgcttt
245581 cttgtaagcg aaaagaagta cgtgttccaa aaataaagca gaaaggcgaa aagggtcgaa
245641 tgtaagacac taaataaata ttttaagaag aggaaaagtc gcctcagaaa cgctaaaatg
245701 catccgattt cccaaagagg aagtctaatg ttttcgattt gtgaaaaaaa gataaaaatc
245761 gaagaaaatg tagggagccg cgcgttaccc ggattgatat ttgagtgatc gacggcgtca
245821 caaaagaaag aatgcttggc taatcaagaa aagtatgtgg tttgtttcat ctaatacggc
245881 tgtcaaggcc cacattggtg ttcaaatgca ttttttatag ttcgtggtta ctgttaatat
245941 tctttcctag tagaatgttt ggggtttagg tatttttgat gttttattta taaatagata
246001 tttatatctt gacgattgtg gtgttttatt tttttttttt tatacatttt tcttttcttc
246061 ctgattcgaa ataaaagtat ttttagaaaa aggataaaga aacagaaatc aaaagaaata
246121 aaaagagtgt ggcaaaatca caactcgccg aattcatcgt agactgatct ccagtgcttg
246181 aaaaatccgt tgaagaactt aacacctaat ccgacatcct tggaccctgt agcagctctg
246241 atgctgtgca tggacaactg tgcaattccc aggtctatgg tacgagcacc tgtttgagaa
246301 gccaatgatg ggccgatagt accacctgat cttgagttgt ttttgatttg gaaatattgc
246361 actttgtctc cattgcggcg tgctaattct tctactaggg cagttcctac gacatctgtg
246421 gccatatgac cgttaggatc cagtgataaa gtgattccga cattaggcac tggaaaatga
246481 ttcttcaaat agacttcagg aaagtttggg ttgtagaggt ggttgacgtc tgcggacaag
246541 atgatggaat tagcccaaac cgtatgcaaa tcgaccggtt tcttagtgaa tgcagaagaa
246601 ctgcgttcca ccactgactc caacaagcca ccttttgcgc cttgtcttgt caacgatccg
246661 atttcttcat tatcatacaa agtgacagta gagaataaat ctgattcctc ggtattaaca
246721 tccttagcgt agcaaatcaa agcaatcatt gctgcgaaac tacacaacct gtcatctaga
246781 cgtggtgcaa aaaggaagtg tttaccaata cctccaatgg tacccttttg cacatcgaat
246841 aagtctaaat ccatttgaat caattcggac acttccacac cggctaattt ggcaacgtac
246901 cttaacaggt ggatgcagtg tttgccaaat aagggcgatt tcttttcatc atccgtggga
246961 ggttcattac cttcctcatc cggagtgggg aagccgatga ccgggatagt ttggtcctct
247021 ttatcaaatg ggccttcagc aggtttaccg aaatggggag ccaaggaagg aattcgacaa
247081 acaggtaggg gtgtagaatc aaccaaggcg cttttaattt cgttagtgcc cttcttcttg
247141 taaagaaggc gaccaccaat acctaggtct ctgtctagcc acaattcatt cagtgtacct
247201 ccatagggag caacagcaat tcttccgtaa ccttccgctg tgtctttaaa ggagacgggc
247261 ttcaatttga ccgtcaaagc gtccacatga gatccaatga caccgacacc cttttcggct
247321 ctccagtttt tgcccaggat aaaggcagat aggttagttc catttcttat agtgtagaat
247381 ttcccaccat cttcgccaat ggagtcctgc caattggatt tctcgctcaa gtatttgaag
247441 ttatgcttat ctaacagctc cgcgaaaaat gatactacat ggtaagtggt agggttcttg
247501 taaatgaaat caatgaattc ctgtgcaata tcctcataat tgtgctcgag gatgcaccac
247561 gaattttcat tttctttctt ttccttttct tcgttggcga tttggttatt tttagatggc
247621 tctacagtta gcatctgcag agttttcttc aattgttcca gtatttcacg ttgttcctcc
247681 attctttttt tcttaatttt gttggttgtg caggtttcta caattgcact aagattactg
247741 atcaggctct atacagtgta tgtcttgttc tgtgaagtca actgcttata aatgaatttt
247801 tattatctaa tggaacgatt aaggggtgtg tcaactattt cacttaaccc tattctttct
247861 tactgtcgtt tgcttgcata gcctatctta cagtaataga ggtgcaaaac agcatcaccc
247921 ctagttgttt ttcccgaaaa acctatccca gattattttt tttttgaatt agacaagaaa
247981 tcatccgaag acctattatg cttctgatta aaccttgaga aaaacggaag tttgcaacct
248041 ataccctaaa gtagaagctg actaattcat attcctcacg aaatggtgcg acctctcttt
248101 atccatgaga aaaggaagga gtgggttctt gtttgatgct tctttatctg ataccaacaa
248161 gcgcaagaga taagggatta caatgttatc atgcctcaga aagtaatagg atgacatttt
248221 cttgcaaacg ttgacattaa aaacataaag taccttacgg cgttcggagc ctacaagcct
248281 gccacaattt gagccgctgc acaagagaac accgaatgaa caactggctg cagctgtcga
248341 tgaaacctca gcgaataaag cacacatttg tgcgttttac aataacaggg aaggtggaat
248401 gtgttgcctt cgtccttatt tttcgcgttg tgaaatattt ttactaattt ttcttttcgc
248461 gtggtcattt tcgcgttggg ttgtttgggc taaatagtga aaactaatct ccatcacgta
248521 ccgtaccgtc ttgtaccggc tgggagcagc attatagtgg ccactcttat tggcgttctt
248581 aatataagca agttaccttt tgctcgaaac ctgtttcttc ttaaaactcc ctttggatcg
248641 taagttcgct agttatccga ctgcaaggac gtaaattgga cagcgagagg ccattaaaac
248701 agagagttga actcaaatag atcatcaaat aggttggata tccatcatac tacttgctac
248761 taatcgcgaa aagagataaa taataaaatt acaagaaaga caaggtaaaa agaacgacat
248821 agatttgcgg gacaaaaaat actgataaat aaatcaacaa ccaactatat tcactccttt
248881 attatttgtt attaatattt tttattttta ccacacgaca tgactggtca cgtttcaaaa
248941 acgagccacg tacccaaagg tcgcccgtct tcattggcca agaaggcagc taaaagggcc
249001 atggccaaag taaattcgaa tccaaaaagg gcgtcggggc atttggagcg tgttgtacaa
249061 tctgtgaacg acgctaccaa aagattatct cagcccgact ctaccgtaag tgttgctaca
249121 aaatcatcaa agagaaaatc cagagacacg gtgggtcctt ggaaacttgg caaaacattg
249181 gggaagggat cttctggtag ggttcgcttg gctaaaaata tggaaacagg acaattagct
249241 gccattaaaa ttgtccccaa gaagaaagcc tttgttcatt gttctaataa tggaactgtt
249301 cctaattctt actcttcttc catggtcact tccaatgtat cttctccatc aatagcatct
249361 agagaacata gtaaccattc tcaaacgaac ccatatggca tagagagaga aatagtaatc
249421 atgaaattga tatctcacac aaacgttatg gcattgtttg aagtttggga gaacaaatca
249481 gagctgtacc tagttttgga atatgttgat ggtggcgaat tattcgatta tctggtctcg
249541 aagggaaagc tacctgaaag ggaggctatc cattacttca agcagatagt tgaaggtgtt
249601 tcctattgtc attcttttaa tatatgccat cgtgatctga agcctgaaaa tttattatta
249661 gataaaaaga ataggagaat caaaattgct gatttcggca tggcagcatt agagcttcct
249721 aataaacttt taaaaacttc atgtggctct ccacactatg cgtctcctga aattgttatg
249781 ggtagaccat atcatggcgg tcctagcgat gtctggtcct gcggtatcgt tttatttgca
249841 ttactcaccg gtcatttacc atttaatgat gacaacatca aaaagctgtt gttgaaagtt
249901 caatcgggca aatatcaaat gccctcaaat ttatcttctg aggctcgtga tttgatatca
249961 aaaatattgg taattgatcc agaaaaaaga attaccactc aagagatatt gaagcatcct
250021 ctgatcaaaa aatatgatga tctcccagtt aataaagtgc tgaggaaaat gagaaaggat
250081 aacatggcga ggggaaaatc taactcggat ttgcatttgc taaataatgt ctcgccctct
250141 attgtaactt tacattcaaa aggggaaatt gatgaatcca tcttgaggag tttgcaaatt
250201 ttgtggcatg gagtttctcg tgaactaatc actgccaagt tgcttcaaaa gccaatgtcg
250261 gaggaaaaac tattctactc actgttatta caatataaac aacgtcactc aatatcattg
250321 tcctcgtcaa gcgaaaacaa gaaatcagca acagaaagta gcgtaaatga acctaggatt
250381 gaatacgcat ccaaaactgc caataataca ggcctaagga gcgagaacaa tgatgtgaag
250441 actttacatt ctctagaaat tcattcagaa gatacttcaa cagtgaatca gaacaacgca
250501 attacagggg ttaatacaga aattaatgcc cctgtattgg cacaaaaatc gcaatttagt
250561 atcaatacgc tcagtcaacc tgaaagtgat aaggctgaag cagaagctgt aacattacca
250621 cccgctattc ccatattcaa tgcttcttca tcaaggattt tccgtaactc atacacctct
250681 atttcatcac gttcgagaag atcgctacgc ttatcgaatt ccagattatc attgtccgct
250741 tcaacttcta gagaaactgt gcatgataat gagatgcctc tacctcaact gccgaagtcg
250801 ccttcaagat attcattgtc aagaagggca atccacgcct ccccatctac taaatcaata
250861 cataaatcac tttcgaggaa gaatatagct gcaactgttg ccgctagaag aacactacaa
250921 aactcggctt caaagagatc cttatactca ttacagtcaa tttcaaaacg ttccttgaac
250981 ctgaatgatt tattagtctt tgacgatcct ctccctagta agaaaccagc atccgaaaat
251041 gtgaataaat cagaacccca ttcgttggaa tcagactctg attttgagat cttatgcgat
251101 cagatcttat ttggaaacgc cttagatagg atactcgaag aggaagagga caatgaaaaa
251161 gaacgcgaca cccaaagaca gaggcaaaac gatacaaaat cttcggcaga cacttttacg
251221 atctctgggg tgtctacaaa taaggaaaat gagggcccgg agtatccaac caaaattgag
251281 aaaaatcaat tcaatatgtc atataaacca tctgagaata tgtcagggct ctcttcattt
251341 cctatctttg aaaaagaaaa cacgttaagc tcaagttatt tggaagaaca gaagccaaag
251401 agagcggccc tttcagatat cacgaactca ttcaataaaa tgaataaaca ggaaggtatg
251461 aggatagaaa aaaagattca aagagaacaa cttcaaaaaa aaaatgaccg cccgtcacca
251521 ctcaaaccta ttcagcacca agaacttcgt gtaaattctt tgcctaatga tcaaggtaaa
251581 ccgtccttat ctctagatcc ccgccgtaac atctcccagc cagtgaattc aaaagtggaa
251641 tcactattgc agggactgaa attcaaaaag gagccagcct ctcactggac ccatgagaga
251701 ggttccttgt tcatgagtga acatgtggaa gacgaaaaac cagtcaaagc ctcagatgtt
251761 tcaatcgaaa gttcatatgt acctttaaca acagtagcaa catcttcgag agatcccagt
251821 gttttagcag aatctagtac aattcaaaaa ccaatgctgt ctttaccttc tagttttttg
251881 aacacatcta tgacgttcaa aaatcttagc cagatactcg ctgatgacgg tgatgataag
251941 catctaagtg tgccacagaa ccaatctaga agtgtagcca tgtcacaccc tttgcgaaaa
252001 caatctgcca aaatatctct aactccacgg tctaatttga acgccaattt atccgttaaa
252061 cgtaatcagg gctcacctgg ctcctatttg agtaatgatc tggatggaat ctctgatatg
252121 acatttgcga tggaaatacc aacaaacacc tttaccgctc aggcgattca actgatgaac
252181 aacgacacgg acaataataa aatcaatact tcgcccaaag catcttcttt tacaaaagaa
252241 aaagtaatca aatcggcagc ctatatctcg aaggaaaaag aaccagataa tagcgatact
252301 aattatattc cagattatac tataccaaac acatatgatg aaaaagccat taatattttt
252361 gaagatgcgc cctccgatga gggttcatta aatacatctt cttcagaaag cgattcacga
252421 gcaagtgtgc ataggaaagc ggtatctatt gacactatgg cgacaacaaa cgttcttact
252481 cccgcgacaa atgttagagt aagtctttat tggaataata acagttctgg tatacccaga
252541 gagactactg aagagatact ttctaaactt agattgtcac cagaaaatcc ttctaataca
252601 catatgcaaa agaggttttc ttccacgcgt ggtagtcgtg atagtaatgc attaggcatt
252661 tctcaaagtt tacagtcaat gttcaaagat ttggaggaag atcaagatgg gcatacttct
252721 caagctgata ttcttgaatc aagtatgagc tattcaaagc gaagaccatc tgaggaaagc
252781 gttaatccaa aacaacgagt gacaatgctt ttcgatgagg aggaggaaga atctaaaaaa
252841 gtaggtgggg gaaaaattaa agaagagcat accaagctag acaataaaat atccgaggaa
252901 tcttctcaac ttgtgttgcc ggtggttgaa aaaaaggaaa atgcaaataa tacagaaaat
252961 aactactcta aaataccaaa accctcaacg attaaagtta cgaaggatac cgctatggaa
253021 tcaaatacac aaacccatac aaaaaagcca attctaaaaa gtgtccaaaa tgttgaagtt
253081 gaagaagcgc cttccagtga taaaaagaat tggttcgtca aactatttca aaacttttct
253141 tctcataata atgctactaa ggcatccaag aatcatgtaa cgaatatatc atttgatgat
253201 gcgcatatgc taacattaaa tgaattcaac aagaatagta tcgactatca attaaagaac
253261 ctagatcaca aatttgggag aaaggtggtg gaatacgatt gtaaatttgt aaaaggcaac
253321 ttcaaattca aaatcaagat tactagcaca cccaatgcat ctacggtaat tactgtaaaa
253381 aaaagaagca aacattcaaa cacaagttcc aataaagcct ttgaaaagtt taatgatgat
253441 gtggagagag taattcgaaa tgccggacgt tcataaattc tatatagatg ttatataatt
253501 atacaacaat aatttgaaaa atttaacgta cgagaaccga atggacaggc gtgagaaaac
253561 atagtttaaa agaacattaa taaatggaga gacatgagac acgaaggaaa gaaagagggt
253621 tttacaaaca ttgtcctaga ttagaagata aatacaaccc tggaggggta aaaagagctg
253681 tcgtttcttt tggagctcaa gaagattcgt catccaagag atcttcttca gaaagctctt
253741 cctcagagct gtcactgaga tcttcctctt gcacgaattc ttcatcatcg tcaaaatttt
253801 cgtttacatc atcaccaagc aaggcatact tgtcggcatc attatagtat tctgatagga
253861 tgaaggtcga ataagttata gagttctcct ttttttctat cgcttttttt aaacttttat
253921 ccacttcaat cgtatcatac tgaaaattcc aaaactgctt aaaatccttg ttccagcaag
253981 ctaccaaaat agtactaatc aacaaggaag gaacaatgta taataaagcc ggttgagcag
254041 tattgaaaat ggacaaggag accatggcag ataccaaaga agcaacgtaa ctaaccatag
254101 cagtaataaa atattttcca acgtatgacc agttcaaaaa gtggaattca gtgtcatcat
254161 gatcaaggtg ccacttccag atgtcatatt tgtagcacat cgcaataaac ataccaggca
254221 aggcaatatc acccagacca agtattgaaa aattgaagtt gttttgagct gtattaaact
254281 tgactggtaa gcttagtttt acgggaatat caaggttagt agctactgta accattacat
254341 cggtaccaaa gacaaagcaa atgtcgtaaa aaaatagagc aattaggatt agggcccctg
254401 attttaaatt cttcaatttt aattgagcaa tggaccaaat agccatattc atactgacag
254461 cattggatat taaccaatca ttgggtgata aatagaaata tacggtagaa acgatggaca
254521 gaacgaacga aacaattaat gcgctattca aatacatgtt gctgatctgc ctcttcgatt
254581 taatatcctt cggttcaact aattctcttc tgtaaaaatg cttcatccaa tgatcttttt
254641 caatctcatc caatgttttc ttgtgaacaa ctgagttggt caatccatct ttgtaattca
254701 aattggtaac aaacccgcct atcttgttca ggtcttcgtt atcatcagct attgttacac
254761 gataccttgg taaaacaacc aggggattcc aagaagctaa atgtgatagg tttctgaaaa
254821 gtgagttgag aaagtaggag tagacaaatg tgccagctgg gatatttagc agtgttatat
254881 taaaattcaa aattttcacc acatatttta gccagtttag gtgtagtttc ttgatcacaa
254941 aatagagagc gagtaaagta cagccactag ttaagggcag tataatcgca tgtttttcat
255001 ccatcatatc gaaaaacctc ttgcttttct tctttttctt tttatcttcg tcattctcgc
255061 ggtagataac atgacagtcg tggtccacat caaaatctgt aggatcaaac aatgagtgtt
255121 ctctcgtagg aggtagagct gtaaatggaa tagaagaaat agacgtaaat gagccaataa
255181 cgaccaaagc acttgcgatg agaactaaag tggcgtagtt gaatactaaa gaatggcttt
255241 ccaccaagtg tgtaatcttg tgagcaacgc gatatgatat cttatcaaag gcagtggtta
255301 atttgttatt gtggttttca actatagcat tgatctgttc aaaaacttgt tctaattcct
255361 tgttcgacgc actttggtta gcgcttgatg aattgttcct aaaggcacga gatgaccact
255421 ctgaaaggtg gtcaacaaat gaattcaaat acttgtccat cgtgtatgag tttgttcccc
255481 attatagatc tgtagtattg ctcaaaaagg gagcacttta caaatcttgt cctaaatact
255541 cccattcgga gaggggttct tttttttccg gtgcctcaaa atcctttttt ttttgatggc
255601 gcaaaagaca cttaagaaaa gtgaatactt tttataaacg taatcctata aaacatgaaa
255661 agaaggatta cggaacgtct gcctgattca cttatatata ctatatagat ggtaaaaatc
255721 taacgtttcc gttgtttctt ccatttaaat gaaatttttc ctgaagagtc tacgattttt
255781 ttcttggaac ccttcttcaa caattctctt tgagcatcca ttctttgttg gacctgtttc
255841 aattgagttt ccctctgtaa gtgctgcttg acttgcttga actttttcaa tttctttttg
255901 tctaatgatt cctttggcat tattgatgaa gcgttcctat tgtttgaaat atcttgggct
255961 aattggtcct tagttaatct attttcagat ctattcacca tctcggaggt ggtattgaaa
256021 aacttctctg gggtgaattc gttcatcttc tctcgggaat cgacgaatat tgtatgattc
256081 ccactgcttt tgaacatcaa ctgtttcgct cctttctcca gctttttcag ctctatttgc
256141 ctcagcgtcc tcacataatt actatcttgc gttttgagta atttaacttg atccatggaa
256201 agcgattcgt cttcttcgtc accgtgacgt gagctgatca gcagtccttt tgcatctgtc
256261 ttccttgaat gcatagcatg gtagtattca tctggatttc tctcttttgc tttttctctg
256321 aggactttca aagtggactg cttcctgtgg aagtcttgag cacgtttcac atagtcttta
256381 tgcttttcta aaaacccata tctggaacgg ctagttagct gagaacgttc tctatgctgc
256441 tttttctgaa catcatgtac aagtttagcc atatcttttg tctgttgttg gctgtaacga
256501 actagaaaac cccactagta ttattcgatg atatgcaact tgctcttatt gtagtttctt
256561 agcattgttt tctttactct ttttcttcaa atcgcgatga gctcatctag ccataaaaaa
256621 atttcatctt ttacgtgcat aacgacaaac ctttaagcct tagaggactt ggtgatgtgc
256681 tcctttataa caacgattac ttccattgaa cagcaacacc tgcaaaatcg gagctgcaaa
256741 attattgatt ggatgtggca aaaataggaa tgggcgatca taatctgccg gattttcaga
256801 catgtttgaa gttttctgtt acagctaaaa agagctttct atgtatgtat agagacagcg
256861 tctcaaagga aaaattagcc tcttcgatgc caagtacttg tgatatacaa ctgaagaggg
256921 caatcaatga cgcttatccg ggcggaggaa taaaggtcac ggttctgaac tcaacaactg
256981 caagcttgga ctcgttagca actacacatg ttaaggaatt tgagattgtt atcattccag
257041 acataaattc tcttttacag ccagaccaag cgaaattagt aaaaattatg agagattgca
257101 cagtggcgat tgagaaggca cagtcaacac gtatatttat aggagtggtt cattggaata
257161 atcccgtgca gccttcaggc gccgctaagg atggggatga agcaggtaaa ccagctccca
257221 aaactcgcat cttcctgccc acgtctttcc gtatgggcgc ttggctcaaa cacaaattct
257281 ggtttgcatg tgcaccccca tatttggatt ttgaaagttc aactgagtct agcattaata
257341 caagagccaa taatagcatt ggtatggctg aggaagagaa gcaggagcca gagagcaaga
257401 ggtcgatcat attaaatgaa gaggcaaatc tgaacgatgt atttgtgggg tccactgtaa
257461 gacggtatat tctcgatatc atggtccatt tgcgaacgca tagattgacg tataacgcca
257521 aagccggcgg ggtatataca aattcattgg acgacgtggt gttattgtct agattaattg
257581 gtctacatag cggcaagatg tttgtgtcac cttcacatgt caaagaggcg tccaggtggt
257641 acttccccat gcacttggaa ttggttcagc gttcctccat ggatagttcc ttattgtacg
257701 gtagcgaccc caacttggtg gacgaaatgc tagagaaact tgcgaagatt aagtgtgagg
257761 aggttaatga gtttgagaat ccccttttcc tggaatctct cgtagtgaaa aacgtactaa
257821 gtaaagtcgt gccgcccgtg taagtttatt atgtatttcg agcatgcatc tggaacctat
257881 gtttacatac gtacaaacgg tatttaaaag tttctattct tagcgtcaat tgccctttat
257941 cgttttgtta accaattgtt gtttttattc attatgccat gacccgaaaa atgagcaaaa
258001 tcggtcaaag taaatagcta aatatttggt ctaaaaagta agagagaaat gaaaatggca
258061 aggcttaact actttgcaat agtgtatata gacattacca attgagtcca gcaacgaaag
258121 attccgcttg cacttggtca atcatttact gaccataata cgaagtaata gagatgctac
258181 taaaagatga ccatgcgatt acaatttaca atagacaatt aagcgcaagg acaatcagta
258241 tgcattccat ttctaataga caaggtgcta tgagtgaatt gctagcctcc cctttttatt
258301 ttgtgcggtc accgcaaggg acaaagcttt tcttagaaaa ccgtctgaga agcataacgt
258361 acgccatccc ctagacatat taataatgct acagatacta tgctgctcgt ctttttttga
258421 cgaccctttt attgcaatgt gcaactaatg gcaaacaacc acatagtatc acagtattac
258481 attgcctcca ccgatgcgga tgttagggcg ccaagtctgt catgaagcat gttcctgtca
258541 taatcttgta tgcaaaatac cgcgttctgc gccactgata tgctaggcag cagcaaccta
258601 tgcagaagat tgcttttccc acgcctgttt tacgtctcca gggcacttga aacaatgcag
258661 cgatcgccgc cacaacacgc caaagagaag cgaaagtggg cctgggcggc ctcagtttcg
258721 gcagaggtaa acaacacgaa ctgaactgcc ttagctccga agggcaattc cacaggcact
258781 ccgcggggcc cggccaaggc ccaaaaggcg tggaatatgc gcgttttggg gccataacac
258841 ccagtaccac ggccggaacg ggccatataa taagtttttc actctcaaga atggtaaacg
258901 taaataggaa catcccacta ccctagaaat tgcggaaatt tcgcgcttat cattagaaaa
258961 tctggaaccg tcctttttcc tctttcttgc atttcccttt ccgtattatt gccattcttt
259021 aactgcattt ggggaaccgt agaccaaaag ccaaacagag aaatgtaacg ttctaaaaaa
259081 aaaacaacga aaaaattgaa aaataagata caataatcgt atataaatca ggcttcttgt
259141 tcatcatttt caattctctt cttgccatcc cttttcctat ctttgttctt ttcttctcat
259201 aatcaagaat aaataacttc atcacattcg ctacacacta acaagaaaaa aaatgcaatt
259261 ctctactgtc gcttccgttg ctttcgtcgc tttggctaac tttgttgccg ctgaatccgc
259321 tgccgccatt tctcaaatca ctgacggtca aatccaagct actaccactg ctaccaccga
259381 agctaccacc actgctgccc catcttccac cgttgaaact gtttctccat ccagcaccga
259441 aactatctct caacaaactg aaaatggtgc tgctaaggcc gctgtcggta tgggtgccgg
259501 tgctctagct gctgctgcta tgttgttata agaaatctct gattttttat aatatctata
259561 tggctttttt caaaattttc ggttttacta ggtaagtgtt tgattctttt cttttcgtta
259621 atatattttt acacataatt ttaaataatt tttgttattt tgaataggta gataccataa
259681 aaataaaaca ctttttactt taacgatgtt cctgtgattt ctcttcgaat gagtcaaaaa
259741 tttgaactcg aaatgaatgt attagagact gggtttcttc gagtttgctg agatcttggc
259801 tatgcacaat gtttcctgcg cccctaaggt gaaaaaaaca tgcatgcttg tttcaacaga
259861 ccagtgtgca taaagaattt cgcccttagc tgcgattaaa gagtcaaggc gtgaaaaaca
259921 taggcgaaag tgctgaccgt tcttcccttt atctttttac catcttcgtt atctgttacc
259981 tgttcaaaag aaagtgggaa agatattggt gtgctacggt gggatctttt ttttctgcca
260041 ttttctatac tttacttcca cttataaaat attttacaaa ttcaagggag acgtgtgaca
260101 aaataataat ctagaactca atgaactttt gtcctcacta caattgcccc tcggatggat
260161 ttgaacttac aagaaatatc acgttggcgc gcgctaaagt cgcttgccaa tgcgctatga
260221 aattttcatg acctggcaca ttttagcaca gtgccattaa tccctttatt atgggcattg
260281 atgcgacttt aaaactgtac cttccttcgc acatgctgaa ttttcttaat gagattcatc
260341 tacgatgctt tagagctagc cttgttttct tttttatgct tcaagagtaa gtagtgaaga
260401 accccactag acaaatacta agggatgctg caaccacgtc ttatacttca cccatacata
260461 acattggaat ctcattaatt tttgcaaaga tatggtgaac aagtttcaaa ataagaatgt
260521 atgtgtaccg aatcgtagct cgaggtaata atgaaaaaaa aaatcggaca tctggaaagt
260581 tacgaatata gaagcagata cccctcttga cggcaaacat tgtgtgctcg accttctatc
260641 ccgttaaaat atcataataa acaaacccct cccgcgaaaa caaaaaaaga gagctaaaaa
260701 aagtacttct tcgcgttata gatggtgccg caccgtacgt cataactaaa aatagcgtta
260761 gccacagctc cctgaacgaa aagggccctt cggcccgatt ggaatacggg tccgcttacg
260821 tctgtgcgtg cgggttgtcc cacaacggta acttactcca ggagagccat ctcgaaggtg
260881 ccacaaaaga aaacaaaaaa aacaacaaac aataagctct gtggttcacg ttcaatgtag
260941 tgttttttca ccttttaatt ttgataattt gtggtgcaga aaaaaaaaaa gcaaacaaac
261001 aaaatctcaa ttatttaaag gacgatctta acgtttcttt ctttcgctat cttccttgaa
261061 ttttttttct gtctgaagta aaatatcccg taacaaacta ataaatacta cgaaagtctc
261121 aaaaaacaat aatgaaattc tccactgctt tgtctgtcgc tttattcgcc ttggctaaga
261181 tggtcattgc cgattccgaa gaattcggcc tggtgagtat ccgttccggc tcggatttac
261241 aatacttgag tgtttacagt gataacggca ctttgaaact tggcagcggt agtggctcat
261301 ttgaggcaac tattaccgat gacggtaaac tgaaatttga cgacgataag tatgctgttg
261361 tcaatgagga tggctcattc aaagaaggtt ctgagagcga tgctgccact ggtttttcta
261421 ttaaagatgg ccatctaaac tacaagagct cttctggttt ctacgctatc aaggacgggt
261481 cgtcttacat tttctcttct aagcaatccg acgacgctac cggtgttgcg attagaccaa
261541 ctagtaagag cggatctgtt gcagcagatt tttctccaag cgactctagt tcctcttcat
261601 ctgcttctgc ttcgtctgct tccgcatcat cttctacaaa gcatagttcg agtatagaat
261661 ctgtcgagac ctctactact gtggaaactt cctctgctag ctccccaact gcttcagtta
261721 tctctcaaat tactgatgga caaatccaag ctccaaacac agtttacgaa caaacagaaa
261781 atgcaggtgc caaggctgcc gtcggcatgg gtgctggtgc tctagcggtc gcagctgctt
261841 acttgttgta agtacgagaa caaaacctgc atgttttatt tccttcaata tagctttcta
261901 cataatgatc acttacatat agcgtaatgt aatatgaaat ggcccataat attctcttac
261961 attgtcctcc tacctacatt ccttttcttg catgcagctc tcacattccc cgattcgctt
262021 gaaaaattta aacttgtaga aaagtaggtg aatgtcccgc cggcggtttc tctgctgcat
262081 gtagaaagat ggatatacag aaaaggagat aagagtagct atctcaagtt tgttccactg
262141 actgctaata cgcatagagt tgttatttat tgtacatatt cgaaaaaaag caagaaatca
262201 ctacggtgac ctcagtagaa cgaactaata agtcaaacca aattaaccgt ttccaggctg
262261 ataggagaat acaagaatgt ctgaaagaaa agctattaac aagtactatc caccggatta
262321 caacccactg gaagctgaaa agctatccag gaaaatggct aaaaaactga aaaccatgaa
262381 taagagccac gcatcgatta gattaatgac cccatttagt atgaggtgtt tggaatgtaa
262441 cgaatatatt cccaaaagca gaaaattcaa tggtaagaaa gagctactga aggagaagta
262501 cctggactcc attaagatat atagactaac catttcatgt ccacgttgtg ccaattccat
262561 tgcatttaga acagaccccg gtaattcaga ttatgtaatg gaagtggggg gcgtaagaaa
262621 ctatgtccct cagaaaccaa atgatgacct gaacgctaaa acagctgtcg aaagcataga
262681 cgagacactg caacgcttag tgagagagaa ggaaatggag cagaacgaga agatgggtat
262741 aaaggagcaa gcagatgaca aaatggattt gctggaaaaa agactagcca aaattcaaca
262801 agagcaagag gatgatgagg aacttgaaaa tttaaggaaa aaaaaccttg aaatgagcca
262861 gagagctgaa atgataaacc gcagcaaaca cgcacaacaa gaaaaagcag taacgactga
262921 tgatctggac aacctcgtag atcaggtatt tgacaatcac aggcagcgta ccaataaacc
262981 tggcaataac aacgatgaga agagaactcc gttgtttaat cctacatcca ctaagggaaa
263041 aatacagaag aaaagctctg tgcgtacgaa tccgttaggg atagttataa aacgaggaaa
263101 gtctctcaaa tgacctagaa aagtaaggaa cgtacgattg gtatcatgat ctcttgtgat
263161 gctgtgctac tgtggttgct tccacactat agcgtccatc gctacttacg aggggcgaca
263221 gccccttcgg acttcgaagt gtctggccgt tttttcattg aattttctta taaatgaata
263281 catatcggaa aagccattgt tgactaaagc aagccaaagc cacacaaacc gaggacaaat
263341 agaaaagcat ggctccgtat ccatacaaag tgcagacgac agtacctgaa cttcaatacg
263401 aaaactttga tggtgctaag ttcgggtaca tgttctggcc tgttcaaaat ggcaccaatg
263461 aggtcagagg tagagtttta ctgattcatg ggtttggcga gtacacaaag attcaattcc
263521 ggcttatgga ccacttatca ctcaatggtt acgagtcatt tacgtttgat caaaggggtg
263581 ctggtgttac atcgccgggc agatcgaaag gtgtaactga tgagtaccat gtgtttaacg
263641 atcttgagca ttttgtggag aagaacttga gtgaatgtaa ggccaaaggc atacccttgt
263701 tcatgtgggg gcattcaatg ggcggtggta tctgcctaaa ctatgcctgc caaggtaagc
263761 acaaaaacga aataagcgga tatatcgggt caggcccatt aataatttta catccgcata
263821 caatgtataa caagccgacc caaattattg ctccattatt ggcgaaattt ttaccaaggg
263881 taaggatcga cactggttta gatcttaaag gaatcacatc tgataaagcc tatcgtgctt
263941 tcctcggaag cgatcctatg tctgttccac tatatgggtc gtttaggcaa atacacgact
264001 ttatgcaacg tggtgccaag ctctacaaga atgaaaacaa ttatattcag aagaacttcg
264061 ctaaagacaa acccgttatt attatgcatg gacaagacga cacaatcaac gatcctaagg
264121 gctctgaaaa gttcattcag gactgtcctt ctgctgacaa agaattaaag ctgtatccgg
264181 gcgcaagaca ttcgattttc tcactagaga cagataaagt cttcaacacg gtgttcaatg
264241 atatgaagca atggttggac aaacacacca cgaccgaagc taaaccataa cctatacagg
264301 acttaatcac ttagacagta tacaaataca catatacatt tatatttcat cgagaatgcc
264361 atcagtaaat attatttgca aaagtcgatc agcatattag taaagcagta aattaaaagg
264421 taaaccaagt cacaatcgac cgattgcctt gtcgaagtaa aagaaaaaaa tttaagagcg
264481 gctccccttt ccccggaatg ggaaatcaca ttatccgtgc ggcgttttct gagcgaaaat
264541 cattgcgatt gccaaacttt tggtagccat ctgggggaac ttttgaccat tttttccaat
264601 gatgaaaatg tattattggt gcgaatggcg ctaaatacag aggttttttt ttctccattc
264661 cacccttaga agtttcttgt tcaattctca ttttaactgt tgcgtttgtt atcgattaat
264721 gtgttctgaa ctcgagtaaa agaacaggtg tgtgtgctaa gtaagaagaa ttattacatt
264781 tacccaacat gaggatggaa aaaacaacag acaaaccact ttctgcagga gatatgaacg
264841 atgaatattc tcggggtcca atcgacgata tagactgttt gaactttttc gaaagggctg
264901 ttcaggaccc atgttgtgag gcctgtgaca cagaagatgc agatgaagaa ctgagagcaa
264961 agcttagtag cttcaatttt cagcctgatt catctccgtg taatgctaaa tgtcaacaga
265021 cactgaatcc actgtgtaaa atagatgaag cactcccagc ggagtcagaa ttagctccat
265081 cgagaaacgg ctcagtatct gaggcaaatt ctgatacaaa ttccatagct tctactgtcc
265141 atgaccctgt cgactccaaa tatggaggca tgcctagctt gagaaaggcc aaaacaacgt
265201 cgtactttac ttcatcttca tcgaacaata ccacaatgag gaacccgcta aaaaaatgta
265261 ataccaatat aaatggcctt ttagtgaacg gaaggagctc aagctcctcc agacagtcta
265321 taccagagct ctttagcggt gcgtgtacta aaaagaaaaa caacgtatta ctgaaaagtg
265381 aaacacccaa ttcagaattc tctagtaact cacttcaaca ttgcaactca aggtcgtttt
265441 ctctacccag gtcaagatca aggtcttctg ccattgccat accaacacat ttgtatggct
265501 tggaaaagta cgtttcacct gggttggata ctttgactgc tgacccagaa gaaagtattg
265561 aaaggttttc aaataatcgg ccccgtgaaa tatcatcgtg ttgtccgaac gatacagggg
265621 acacctcctc atcattatca cattcgaaca cttcctcatc actaaatttc cctttaggta
265681 caaatacaaa tcaattccac caaccaaggc agccagtaca acagcaacag tcttcgaaac
265741 caaactttgg tgctgggagg aaaaaatctt tcattgagat gtcactagca agttcctttg
265801 caggctaaca ttctcgccac cttggaataa ccgtatgatg ttcaactttg ttatttattt
265861 ccacattctg gatcgccatc tgttcgtttt tattaaatat aatatatacc catttgtatc
265921 tcctgtttgg tttccaaatt tccatatact tatcgctgtc tatcatctcc tctcgaagca
265981 tttttttata tactatatta tgagaaatct ttctgaaaaa ttatgaatta cttttttctg
266041 ctgatagtac aacccgctat atactgttac aagtagtgaa taaagaagta aaaaaaaaaa
266101 aactttcaaa ggaaagaata tgaagtgaac atttttttct acgattaaga tccccctgtt
266161 tcttttttct ttttgaacca tcttgtcagc ttacgggaat tttgttcttt aggaacatct
266221 gcgttaggag gtttcctcat tatcctagat aactttgtcg gggaaaatct attccccaag
266281 ttacctttac cttgcgagtt tggaagcgtc aagtaatcat ccttggctcc attttccgat
266341 gatgttccat gtaccgatgt tttgttgcta ctcttgggat tctcatcact tacatcaata
266401 gtcaaaaatt tacagtaact atctccaact gtgttattgg atttactaga gacacctttt
266461 gtgaagaatt tctgcaatct tgcggaagag ttttcatttg ttggtttatt tagtagttta
266521 agaacaattt cttttccctc ctttatttct tcataaaaaa ttttatgtga gagtgaaatg
266581 gagtattttt tgtcttcaaa caaagtgctg gaagcacatt cataacctga caaccgtttt
266641 ctaatatgat taatcctatt atagagtaaa catgactctt gctccaattc tttcattgca
266701 tgcttttcct cttctgcttt cgggattata gaattaaatt tgatgcctga attagcgcca
266761 ttatccaaat ctctgcttct ggaacctaca tcatcgcttt tcagtaggtt cattaaatca
266821 tctccgaaga tctccgtgtt gttttcagtt attttctcaa attctaactc tccaatttct
266881 ggcttaacct caattggtga atccaaatct tttttatcca cagacaaatt taggctgcta
266941 ccgcttaaca ggccctcctc ttcgattaat tctcccttcc caccattatc catgtgattg
267001 tatttttcca tcttggtcat atcttcctga ctgaaattaa caatcaagtt aacaaactca
267061 gtttctctca aattcttatc aagcagataa ggaatctgag gcaaatcatc caacatcgtt
267121 tgttcaatgg ccaatttggg tctcgaaata gtagaactta ggttcaatat ctttgaatta
267181 aaatctagtt tcttttgcgt cattttatca atgtaatcta ataagtcatt gtgtctttta
267241 tcgataaagt tattcatctt cattagccag ggctctttgt ttgcaaactg cgtcaaagtg
267301 gacagattaa gtaaaacttt acttattagg gtaagattcc ttcttgctgt ttcgtttaaa
267361 ttttgagaaa catatttgaa tagcttaggg tttaatatga ctggacaaaa aaaccttaaa
267421 aacaataatc ctgatatacc attcaaaatt atttgcaaag tgtcatcgat acaaattatc
267481 tctagttttt gcctaaagat ttttaaaaca tttcttattt caatcggcag gtcattactc
267541 gttgcataca gccttttcca aatcttcgta acccaagaat acaatcgttt gtagttgtcg
267601 gcaattattt tcctcttttt tacttcatct ttttctttta ctctagcagg atccaattca
267661 catgatttgt ttgactcaat gatctctttt agtattgcac taagcgcttt actcaaatat
267721 tcattaccca ctctgaaaaa gtactgttca atcgactttg ttaagataga gttaccacgg
267781 aataaactgt tgaaaacatg ctttgagtct aaatttttct ggtttattct tgaaaccgtt
267841 ccatcaattt tagccaattc tttgtctata aggacgtgga accattcttc tattcttgac
267901 aaagattgga atatatcgag aaaaattatg gatgtttgcg tcaatttgtt atcattctcc
267961 attgatgaag aagatttgta aattagattg gaaaccatgg acaagtttgc gttcatcaaa
268021 agtttttcca atttaacgaa attggttgac ggtaaaatga agttcaaatt tgaagaaatt
268081 ttaatacaga ttgttcctat ttgaaaattt ttgttatcaa cgtccatgat gggtagtctt
268141 gtttccttat tatatcttgt atcatttatt atttcttgtg tgatttttat tttgcctatc
268201 aatcgtaacc gttttttatt attgagatcg tggaataact gcttgatttc cagataagaa
268261 ttagtaagtc ttaaaagttc attgaactga aactcttctc tccaaaatgg attagaggag
268321 tttgaaacca tggatgttct agcccatgta tggccccagg ccgttatgtc tgtgaatatt
268381 gaccatggcg tattattctt gtcatttaaa ttgattgact gaaaattagc ttccagtatg
268441 gaaattttaa agctattcga tatcttcata tcatttgatt tatctgagcc agtaatagat
268501 aagtattccg acctagcgaa cgattgtaac gctataaaac aatcctccag gtctattctt
268561 aagggaaact ctacaataat ttcttgagaa atatcactag agttggtggc agcactggca
268621 atattttcta tgcgaaactt ttcgaggccc aactggctcc ttagtaatgg caattcacct
268681 aaaaacaaac tgttttcact ttgtaaaaca gatgaatcca gaattcttat ctctgatctt
268741 aaaagctggc taatattcaa tgagtaaatc agagagccgt cactctgtaa aagaagatct
268801 agcatgccgt ttgatttaag cacccccata gcggaaaacc aacctacgct gttgtcatca
268861 ttattaatta tatcagggct ttctaaaata tttgttgctg gcggaaggac gatgttctta
268921 acgatgggcc caaaaacatt caatttgtaa accagcaaac tttctggttt cgccattttt
268981 ttgcttttaa attctagagg tcgcgatact tgaaacttat taaatatacc atttgtcttc
269041 attgagctcc accagatcag acatgttagc aatttcttga aatcactcca acttttaact
269101 cgcaggtaaa ctttattatc tttacctgag gtgtttactt ggattataaa attacaattt
269161 gcattaatat ccttaaaaga ggaatgctta tccttaataa tctcgattct acattgctgt
269221 agatgtttga taattggctg aatattagta gagtctgctg ttaactcatc gattgagtgg
269281 gttagtgcac ctgtactggt aatttgcaga tagtgtgtct tccagtcgtt taaggacagg
269341 ttattacacc actgaatctc acccttaaag gtattcttgt aatgcttaac gttggacaaa
269401 aattcattca atttgaaata tgatgttcga ctttgggccg gttcattgtt ggagctcata
269461 atatgataca atcaaagata aacaccacga cgtatgcacg gataaagttt tcagtctgac
269521 cgagtagtta ttcctactat tttgttgttt cttcctccgt tttcataaat ggcgtttgtt
269581 tggatacctt tcttttttat cgaacagaac gcgttcaaga atgaaagtca ttaattatta
269641 ttagatacag agatatacat attatagagt atgcatgcta tattcacgga aagctacgac
269701 gaaggcctgt atcatagtta gctggtaaca gtaaatttac caaaaatgtt gggaatttca
269761 ccttctggtc cgatgtatct agggtctctc cagggaccaa tatcggaata gtagaactta
269821 tcattagggt tgtgcaagac agatgtacca ccatatttaa caggcaagtt ctcgattgga
269881 atttgtttta ataattcctt tttataagaa gagccaagaa taaagatttt tgacacggtt
269941 actggatcca agaagggttt aaccatcttg aacatcgtcg agaaaccaaa tggactgtgt
270001 ataatataaa acttacccat tctttcagga taataatttt gactgatatc tgcaacatct
270061 ttaatatagg aaagcacatg ataagcatta gaaagtgaga tacccttcaa gtccagcaca
270121 gtgcacgaag tttcaataag gtagccagct cttctcgaac acgctgggac ccggtacgtg
270181 gcaaataatt cgtactcctt gactaagttt cttagcatct gtttttcggt agtgatcttg
270241 tacattttct ttaagttaat tcctcctagt tcttcgaagt acaatggtct cccatcctta
270301 tcaacgtgat ggtaatactg agggtacatt ttggccaatt tgattctttc tttgtcttcg
270361 gcttccttgt tgttttcata atcctcgata atagtgttgg caccgtattc ttccctccat
270421 cgttcagttt ctacaaacat ctcaacgcta gcattgatat caaatttcct tgcccgtaga
270481 aatcgcaata gcgtagaatc atccagcctt tctttgtaat tcttttctaa caagattgac
270541 ctaaattgca aaagcgcttc ctcttgctcc ttagtcaaat tgccgggagt acctggcaaa
270601 gcattggggg agcatatttg aggataagta tcgagtatgc tggttgtcat tcttcctttc
270661 cagttttaac agtgcgcaaa tgtattgctt ttcagattta tttccccgtt atacaagttc
270721 aaggaaatgt ttgagtagag agaatcacga tctaaataat aatccgaaga atttaaaaag
270781 gagtaaatag gggcatacaa gagggggaat ttcagaagtg cctgttatgt aaaaaagata
270841 tgataacaca taatggattg cataccagta aatttccata tgtactatgc cgacctcttt
270901 tcatgtaaac gccttgcaaa ttcatactta atgattacaa gaaagtaata tgtaaatttt
270961 aagctcaggt tcaaggttta taagggcctt cgtctctgat agaagaatca agttggtaaa
271021 tccaaatgga agtacgggtc ccaatagcag gtttgatttt tgaaggtgac tcgagatata
271081 tcagctgccg cccctgaatc agcagtaatt ataactgaag agaacggaca atgttttacg
271141 tataattaag gcacataaat tccatctgga gtgttctgaa gtcgcttact tggtgagata
271201 ttgaggtgtc atcagatagg acaatagtag gagaaaggac catctggagg ttaatcacct
271261 gttgtcttac tatccggtcc tcagggtcca taaaaaaata ctttcaacaa aatctggatg
271321 cattgaaaag gttgttttca aacagtctgc agtttgtaat tcacccacat gccttttttt
271381 gtattcatat tagcttttct tgcataatta gggacatata aatcgtgcac acatggatat
271441 ttcttcataa tattatagtc tgattgatat tcaaaatttg aaacatttcc ataaataatg
271501 gataggggac agccaaaaaa aaactgttgt gctcgatcct gaatggaaaa gactgacact
271561 ataaggagac ttattctaga tatcgtagaa caaacatatg ttactttaac gtcgctggac
271621 actcacagac aagcctcagg ggagacgttt gaaaccgtag aggaatacgt atgaaatata
271681 aatcaacaaa catacgtact gaattatgta tcaggatata ttgctttcac agtttggaaa
271741 ttgcctctat caccaagata ttcactgtta aaaaaaaaaa tgcgaaaaaa ttcaaatttc
271801 aacagcgata ttcgccttca gtatatcaat ataaagcaat tatgacacct catttatcgt
271861 gcatataaga tcatgcaatg agtatggata acaatgatga ccatgaatct aaattgtcaa
271921 tcttgatgga catgtttcca gctatttcca aatccaaatt acaagtacat ttacttgaaa
271981 acaataatga tttggattta acgataggct tgctgttaaa agaaaacgac gataagtcta
272041 cagttgataa tgaattacat caactgtacg acatgtttcc tcagcttgat tgcagcgtta
272101 taaaagatca gtttgtaata aatgagaagt ccgtagaatc gactatttct gatcttctga
272161 attatgaaac cctgcaaaaa cttaaagaca atcaagcaaa ttctcctgat agcgtaaaaa
272221 ggaacgaaaa gaaaaataat tgggaatcaa caaacgatca catagagagt ataataaagt
272281 ttaccgacgc tcccaaaaat attgcgcagg aatacttagc cgaaaatggt tttgatacag
272341 taaaggcgat catcaaaatc attttggatt attacgacaa aagggatttt aaaaaagatg
272401 tggatacttt caaagtaaaa cggagtccta atacgactgt gagaggtggt cgagttcaat
272461 catcgacggg gcttgcccac gttttgaaaa agggtaaaga atccgcaaat gttgctcaag
272521 agagtctcaa aaggccaagg agttataagc actccttgga tagtccgcag atggttgagt
272581 taaatgaatt agttgcagat aatcgcgatc tcaaagccat aaaccatgaa tttttgcaaa
272641 aatgcctgca attttatgat ggagatgttg taaaggtgtt gaacatatcg tccttattga
272701 tcgaagatga caagaatatt acgaaaactt ggaactttga cgaaggtttt accttgacat
272761 ccagagataa ttgtaagcaa catttaccca aattttcaac accgcagatt tcccgcagaa
272821 atgaggtagg aaatacttat aaattgcccc ttcatgacaa agaaaccccc gagggagctg
272881 tgccggttat aaataacctg tttcaaacat acagattgga tttccatggt tttcttccca
272941 gtgaagcggt ttcaacactg aaacttgcat taaataagtg gtggtccaaa gaggtagcag
273001 aacgagagtt gaactcccac aacataaact catatggctc aaaagtacag tttgtaagcc
273061 cgttaatcgt ggtaactggt agaggtatcc acagcatcgg cgggatctca aaggttcgac
273121 tgcaggttaa aagttttctt gaaaaaaatc actacatatt ttgggaagaa tcttcctact
273181 tcagaattga gggtaagaag aagaaataaa acctatctga tttttctata aaggttataa
273241 acgctaggct tctttaaact gcattgggtt ttttctcaat ttcgagaaaa ataatataac
273301 gcgttagaaa tggtgatgta aataaatgaa tgttagaaaa atacatacgt taaacaaata
273361 agttagacat tagcacagga cagcacttca ctcatggatt atatgaaatt ggggcttaag
273421 tcccgtaaaa ctggtattga tgttaagcaa gatataccca aagatgaata cagcatggaa
273481 aatattgatg attttttcaa agatgatgaa actagtctta tcagtatgag aaggaaaagc
273541 agaagaaaat catcgctttt cttaccatca acgttaaatg gcgatactaa gaacgtatta
273601 ccgccatttc tacagtcata taaatctcaa gatgatgaag ttgtccaaag cccatctggg
273661 aaaggcgatg gatcaagacg atcatctttg ttaagccatc aatcaaactt cctgagtcca
273721 gccaatgatt tcgagcctat tgaggaagaa ccagaacaag aagaaaatga tatcagaggc
273781 aatgattttg ccacaccaat cacacagaaa ttgagtaaac ctacatataa aagaaagtac
273841 tccactcggt atagccttga cacttcagaa agcccttctg taaggttgac acctgataga
273901 atcactaata agaatgttta ttcagatgta cctgatttgg ttgctgatga ggatgacgat
273961 gatagagtaa acacttcttt aaacacatct gataacgcat tattagaaga cgaattagaa
274021 gatgacgggt ttatacctga aagtgaagag gacggtgatt acattgaaag tgactcatct
274081 ttggattcag gctcggattc agccagtgat tcagatggag ataacaccta tcaagaagta
274141 gaagaggagg ctgaggtgaa cacaaatgac aatgaagatg attatataag acgacaagcg
274201 agtgatgtgg ttcgtacaga ttcaataatt gatagaaacg ggcttcggaa atctacaaga
274261 gtcaaggtgg cgcctttgca gtattggagg aacgaaaaaa tagtatataa gaggaagtcc
274321 aataaacccg ttcttgacat agacaaaatt gtcacatatg atgaatctga agacgaagag
274381 gagatattgg cagcacaaag aaggaagaaa caaaaaaaaa aacctacacc aaccagacct
274441 tacaactacg tacctacggg gagaccaaga ggaaggccaa agaaggatcc aaatgcaaag
274501 gaaaatttga ttccagaaga tcccaacgag gatattatag aaaggataga atctggaggc
274561 atagaaaatg gcgagtggct gaaacatgga atactggaag ctaatgtgaa aattagcgac
274621 actaaggagg aaactaagga tgaaattatt gcattcgcgc ccaatttgtc gcaaactgaa
274681 caagtaaaag acacgaagga cgagaatttt gcccttgaga taatgttcga taagcataaa
274741 gaatattttg ctagcggcat attaaaacta ccagctattt ctggacaaaa gaaattaagc
274801 aactcattta ggacatatat tacgttccac gtgatacagg gaatagtcga agtaactgta
274861 tgtaagaaca agttcttgag cgttaaaggt tccactttcc aaataccggc attcaacgag
274921 tacgcgattg ccaatagagg gaatgatgaa gccaaaatgt tcttcgttca agtgaccgtt
274981 tcagaagacg ctaacgatga caacgacaaa gaattagaca gtacgtttga cacttttggg
275041 taattatgat gtgaatattc tcattatgca tgctatgtac tgaagaaata taactaggtc
275101 catacgctta tactgttaaa catgtgaact tttctgtaag aaaatgaatc acgtaaaatt
275161 tcgcaccgaa ctttcgtaga tgagagaaca aaaagcagaa aaagagaaag aacagtaaag
275221 taacacttag ttagcatatt taaataaaag tctaaaggac cagcaaagag ttattaggtg
275281 tgatgacgga tgaaaaagtg aactcagatc agaatatgaa cggtaagcag ggagttaact
275341 taatttcatc cttgcctaca acacaagtgc cggtttcaat tttgaccaac aaggagagaa
275401 gaaaaagtat tcacgatgaa tcaaatttcg aaagatctga tagtcatgaa gatcaatcaa
275461 aatccaactc taataggagg aatatttaca aaaacgatta tagcacaaat ttgagggatt
275521 tctcttttgc caatctgaag caaaatagtg aaaggaacaa agatggccat gaaatacaga
275581 tcaacaccag tatgccagct aatacaaatg gccagcaaaa aaggttttca ccttcattac
275641 cttctgctgt ttcatttacg gtgcccgagg tggaaaggtt gccgtatcat agatattcga
275701 tatccaataa acctggaaag cagcagcagc agcaggaaca actgcagcaa aatcaacaac
275761 aagaagagca gcaaaaggca caactgcagg agcaaaatca acgagcaaaa cagcaagaag
275821 aggtgaagca aattcaggag caagtgcaaa aaaagcaaac tgaaagacag caactgatag
275881 acgaaaagga gaggatagcg aatgcaatat ttaaggagaa cactactaat gatggtactg
275941 atatcaggaa acattcggta tcgagtggta cgagcaatag cgaagatgaa gtagattcac
276001 cttcgatgga aaaaaattct atcgttcata tgccaggtga ttttatctac ttcaatccca
276061 agtcaaacgc ttctaaacct atcactgcaa aggcggcgcc attatcggct aataactcca
276121 cacataaaaa caaggaagtt atcactgcac ccacagggcc tcgtgtaccc ttcacagagt
276181 tctttcagaa ggaagacgac aagaaattcc acattctcat tggtgcgacg ggctcagttg
276241 ccacaataaa agtacctcta attattgata aacttttcaa gatatatggg cctgagaaaa
276301 tctctattca gttgattgtc acaaaacccg ctgagcattt tttgaaaggg ctcaaaatgt
276361 caacacacgt taaaatttgg agggaggaag acgcttgggt attcgacgct gtgaataaga
276421 atgatactag cttgagtctg aacttgatat tgcaccatga attaagaaaa tgggctgata
276481 ttttcctgat tgcgcctttg tcagctaaca cacttgctaa actggccaat ggtatatgta
276541 acaatttgct aacttctgtg atgagagatt ggtcaccact gaccccagtg ttgattgcgc
276601 ctgcaatgaa tacattcatg tatatcaatc ctatgacaaa gaaacacctg acgagtttag
276661 tgcaagacta tccgttcatc caagttttga aaccggtgga aaaggtatta atatgcggag
276721 atattggtat gggtggtatg agagaatgga cagatattgt agagatcgtt aggaggagaa
276781 tcaatgaaat acggaaagct agggacgagg aaactggtga taaagagcaa gaacaagaag
276841 aacaagaggg tgctgacaat gaggacgacg atgatgagga tgacgaagag gatgaggagg
276901 acgaggagga ggaagaagct ctaaatgaaa cagcatccga tgagagcaat gacgaggaag
276961 acgaagagga tgaggaagac gtgaaaaccg aagtttaaat gcattagaaa agagtatttt
277021 gtgttatgtt ttatgtttta tttttttttt ttttgtttat tccttaaaag aagattactg
277081 ctttttcatt ccctagtttc taaattgagt gcctaaataa gattaaataa atatgtatgt
277141 ggaaactagg gagggtatgt ttttatttac aggaatagtt gtagtaattc aaaagcctaa
277201 agatttccag aaccgtaatc taaagccctc aaaactgttt aattttggtc taacatcgag
277261 ataaataagt ggttgttgct gcgagtttgc atcgttcaga tcggtggaat agaaatcgat
277321 tacgtagtcg acggttttac cgcatctatc tatctgccaa tcatgtctat caaaaggttt
277381 ggccaggtgc aagatacggg acctgaacca ggcccttggt gtcagttttt tggaatcacc
277441 tttaaaattt gttaatttga taccgccaca cgcttcacca ccctgcttgt cttcccagct
277501 tttaatgtag ttccaaaccc gctcattgat ggagttatgt aaaggcacaa ccaccttcat
277561 gtcatctgag ttcggatccc aatttttttt catcattgcc tcgtaaaatt gtttctccga
277621 cgggtatatc cagtttctgt cagaattcgt ccttggtatg gtggaaacct ctctggactg
277681 agagagatcc accgtggtgt gatattcagg cgttttatcg ttatcttgtg ggtttgcaga
277741 gcactctagt tgattgcctg gggcagtagc accaggatgc gcttcgttgc catgttctcg
277801 tagccataac tttttggttt cctcatctac ggggcatttc ccctgttggt ctgaagacat
277861 cataatatgt aaaatagaga cgaatgaaaa gcacgtgaac taacaaacta tttactacta
277921 ccgaaatgtg atgcttaagc ctttggcctc tgcaatacta gcgattgctt tttccctgat
277981 tagtaagcta catcatttat actacatctt tctgtcttag aaggcttaca aacatcgaaa
278041 agctggaact ttgatttcga aaaaaatatg ccgttacccg ttgcgggtcc ctttttttta
278101 gaaggccggc ccagaagtcg ccattatttt tagtcattac agtagccctg ttgggtaagg
278161 atgcgatgca atacatgtca agaggtgttg tatataaacc acaatatcta ccatcaatga
278221 gctatatata cttttcttac tgaaaaaaaa aactacaaaa ccaagtaaaa aaagaacaat
278281 atgtcactac aaagcaacag tgtaaaacca acagaaattc ctctctcaga gatcagacgc
278341 cccctagcgc ctgtgttgga tcctcaaaag atcgacgcaa tggtggccac aatgaagggc
278401 attcccaccg ctagcaagac atgctctcta gaacaggctg aggcggctgc ctcagccggg
278461 gaactgccgc ccgtggacgt gctgggcgtg cgagtcaagg gacagacgct atattatgcc
278521 ttcggcggct gccaccgtct acaggcatac gaccgccggg ctcgcgaaac gcagaacgcc
278581 gccttccccg tgcgctgcag ggtgctaccg gccactcccc gccaaatccg catgtacctg
278641 ggcagcagtc tcgacatcga ataatgatta cgctaataac actacataag aaacatagat
278701 aaattataat tcactaatac aaaatccctc aatttaatta atcaatttct tattcaacaa
278761 ctagagtagg cactagcagt ttgtgcgacc ctcggcgccg gagaggtaca agggacctgg
278821 cggttgggcc ttcctgccag cttctccccc ccttctcggc attcactcag cgttcattgg
278881 ctcaatcacg cgccaagcgg attcccagaa aaatacaaaa aaaagttgcc ataatacaat
278941 ggcggatatt acaatatata tagcttgcgc tttaaaaaga agtgttagca cgcattgggt
279001 gtttgtactg tattcctcca cttaagataa cgaatacaca tatagatata caatatatta
279061 tacgtggaca tctacggaaa ggaagaaaaa aaacaaaagg aaaaggaagg ataccatata
279121 caatgttgtc aagagtagct aaacgtgcgt tttcctctac agttgccaac ccttataaag
279181 tgactgtttt gggtgcaggc ggtggtattg gacaaccatt gtctttgctt ctaaagctta
279241 accataaagt cacggactta agactgtacg acctaaaggg cgcaaaaggt gttgccaccg
279301 atttgtctca tattccaaca aactccgtgg tcaaggggtt tactccagaa gagccagacg
279361 gattgaacaa cgctttaaag gacacagaca tggttttaat tcctgctggt gtgcccagaa
279421 agcctggtat gacacgtgat gacttgttcg ccatcaacgc aagcatcgtt cgcgatttgg
279481 cagcagcaac cgccgaatcc gctcccaatg ctgccattct ggtcatttcc aacccagtca
279541 attctaccgt tccaattgtc gcccaagtct tgaaaaacaa gggtgtttac aacccaaaga
279601 aattgttcgg tgtgactacc ttggactcta ttagagccgc cagattcatc tcagaagtcg
279661 agaacaccga tccaactcag gaaagggtta acgtcatcgg tggacattct ggtattacca
279721 tcatcccatt gatttcgcaa acaaaccata agttgatgtc tgatgacaag agacacgaat
279781 tgattcacag aatacagttt ggtggtgacg aagtcgtcaa agcaaagaat ggtgctggct
279841 ctgctacgtt gtcaatggcc catgctggtg ctaaattcgc taacgctgtt ttgtccggtt
279901 tcaaaggcga aagagacgtc atcgagcctt ccttcgtgga ctctcccttg ttcaaatccg
279961 aaggcatcga attctttgca tctccggtca ctttgggccc agatggtatt gaaaagatcc
280021 atccaatagg tgagttatct tcagaagaag aagaaatgct acaaaaatgt aaagaaacct
280081 tgaagaagaa tatcgaaaag ggtgtcaact ttgttgctag taaatagatt gttcaagatc
280141 agaaatagag tgaaaaatag ggaaaaaaaa aaaaaaattc tactaataag aacggaagac
280201 tactcgccat catgagatta cgacatcttt tttatttaat tctttgttat atttagccaa
280261 ttgaaaggaa ggaaactgcc aaaaatcaac tagagaaaaa ttcatgctat tcgttgctcc
280321 tacacctttt tttcttccgt agacgaggaa aaacaaaaat gattaaatag gcgcgcgcgg
280381 tgtgatggtg atgataatga tgatgatgat gataatgatg aataaacgtt tcggtttacg
280441 agtttcttta aatatacata tatgatataa aaaaaaaaat acgtaccact tacaatttgc
280501 aaatatagat gatcgaaact gccatttatg gtaagacagt ggatgaccaa tctcgatgtg
280561 tccactggca tcttccaaag gatgtaattg ccatcaggtt taaatgttgt gataagtact
280621 atgcgtgctt tgaatgccac caagagttaa gttctcaccc gctagaaaaa tatgatctcc
280681 ttgacgatgc aaataaacac ttgattattt gcggagtttg ccgtcatgaa atgacgtttg
280741 cagagtatta cgactacaat tcaaacctta tttgtcccaa ttgcagatcc ccctttaatc
280801 caggctgtaa attgcactac catttgtatt tccagaaccc tccccccgct atgtgttgag
280861 tgttgttcta taaatgcatg ccatcttaag ctctgctgtg ctcttctcgt taaggaaaaa
280921 atgcgatggt atatatatag atatatatat atatatatgt atctgtatat atatgttcat
280981 acatatatat atatctatta ttgttgttat tattatcgtg attattattt aggtcctccc
281041 ttctttttac ctgtttttaa tctaccctca aatccggctc ttttctttgg tacggcacta
281101 ccgacatact ttcttttcat cttttcttgc ttatttctct ttttaccctt gttgtctttc
281161 ctaatcctca gattctcttc tcttctcttt tgtctttcag atatcgtgtc ttccacaacc
281221 ctcttacgtt cgctccattc aatcgcagac tttctctttt gtgcttcctt tctctttata
281281 gctttgcgaa gtagtttttc gtcatcccta atcttaattc cttctgcttg taacatagcc
281341 ttttgccatt tttccttttc cttctgcttg atttgttcta gttcgtcttt cgcctccatc
281401 ttattcttct tggcttctaa taactttaag tgtgatttta catcattctt agccggaccc
281461 ttcgttctac cagcttttct taacctttgt aaatctgaag tggcccttgc accatcatcg
281521 aatatgatat tttgaaacat tacaccatct gcgttaattt ctgagtcctt cttgcctttt
281581 ttgaatcttt ttttcgaatt gttttctaaa tcactatcga tgtcttccat atcggaatca
281641 gacgcaattt catcctgatc ctgttcctgt tcactttcta gacgctttct ttttttcaac
281701 tcttccttgc gtttcctttg agcaagaata gcctctctag aaccgggtgc tttcctttta
281761 ctcttcatat ctgaaatttt cgcttgtaac ttggaacgta gtgcttccaa gtttttcttt
281821 ctttgtagtt tctcttcctc tgtaatagac ttcttttcga cagatctatc gggctctgta
281881 gtatcttttt tagattctaa tggtatttca tttccctcat catcaaagat caccttaata
281941 tcctcttcct cttcttcatc ttcgtctggt gctattatca taggatcgtt tacttctacg
282001 ttcaggtcgg agtctccttc cacttttgat gttgcttcct tttgcttttg cattttcatg
282061 tgcttgaatt tttcaccagg taggaccacc ggctttgcgt ctttctcctt cttcttcatt
282121 acttctaatg tactagatgt ttcatcatca cgttgctccg ggtctaattt tttcagttta
282181 tcatttttac tctgttcttt ggttttcttc ttggccttcc attgctcttg acttttttca
282241 tcataatagt attttgcagg aattaaagcc aataaaccat cgaaggcgct tgaattagca
282301 cgaaggcgct cctcaagtga attactcatc tcagtctcct atatctttca attcccggac
282361 tttctttatc acttgcaaca acgtctcagt cctcacttgt tattcatctc ttggtcatct
282421 catctctttt attgtacttt cctcttttct ttaccggaga tgagaataaa aagaattcat
282481 tttaaaaaat tttcaatttg gtgtctgggt gaaacttttt aatcgtgtaa tcccaattaa
282541 accactctac tttactttaa ttggtacacg aactcattac acacctttgc ctctattgct
282601 tgtgtcaatc gtgttgagag aggaagccca aaacaaggga aattaacctc tgtaggcaag
282661 ccatcacatt tggcaatagc agccctcatt taatttaatt cggcatgtgg ccggcagggt
282721 aatgcgctct gctgctgaca aaattgaaag aaaaattttt ttcatcaaca gtttgcaata
282781 ctttcttttt catatttaat tcatccattc cgtcgttaat tttgttcaaa actggtgtcc
282841 atccttaata ccaactcaat tctttgattt tggccctcga tagattcaag atgtcccaag
282901 gtactttata cattaataga tctccaagaa actacgcttc tgaagctttg atttcttact
282961 ttaaactaga tgtcaagatc gttgatctag aacaatctag cgagtttgct tctttgttcc
283021 cattgaagca agcccctgca tttttgggtc caaagggctt aaagctaact gaagctttgg
283081 ctatccaatt ttattgtatg ttccatattt tattttaaca cttccacata cattgttttg
283141 cgcgtttccc gttcgtttat ttggcacgtc atttttcttc gaaacataat gatgaaaaaa
283201 aattttatca aacagttatc cctgtctgaa tgggtaataa taggtaacct ctcatatgtt
283261 gatatttgta tttctgatat gtttcttaaa gaaaaatgaa agtcaaaata acaaaaagga
283321 agtacaaagc gtgtcctaat ccaggaaaaa atataaagga ttgttttact aacatttctt
283381 caattaatgg ttgtataacc atcgagatga tgtatattta gtggctaatc aagttgccga
283441 tgaaaaagaa agagctcgct tattaggttc cgacgttatc gaaaagtctc aaatccttag
283501 atgggcatct ctagctaatt ccgatgtcat gagcaacatt gctcgtccat tcctttcttt
283561 caaaggtttg attccataca acaagaaaga cgttgatgct tgttttgtta aaatcgacaa
283621 cctagctgct gtcttcgatg ctagattgag agactacacc tttgttgcta ccgaaaacat
283681 ttctctaggt gaccttcatg ccgctggttc ttgggctttt ggtttggcca ctattttggg
283741 ccctgaatgg agagctaagc atcctcattt gatgagatgg ttcaacactg ttgctgcttc
283801 tccaatcgtg aagactccat ttgctgaagt caaattggct gaaaaggctc taacctacac
283861 tccaccaaag aagcaaaagg ctgaaaagcc aaaggccgaa aagtcaaagg ctgaaaagaa
283921 gaaggacgaa gctaagccag cagatgatgc tgctccagct aaaaagccaa agcacccatt
283981 ggaagcttta ggaaagtcca catttgtctt ggatgactgg aagagaaagt actccaacga
284041 cgacaccaga ccagttgctt tgccatggtt ctgggaacac tacaaccctg aagaatactc
284101 catctggaag gttggttaca aatacaacga cgaacttacc ttgactttca tgtccaacaa
284161 cttggtcggt ggttttttca acagattgtc cgcttctact aagtacatgt tcggttgttt
284221 agttgtctat ggtgaaaaca acaataatgg tattgttggt gccgttatgg tcagaggcca
284281 agatttcgct ccagcctttg atgtcgctcc agactgggaa tcttacgaat acaccaagtt
284341 ggacccaacc aaggaagaag acaaagaatt tgtcaacaac atgtgggctt gggataagcc
284401 tgttgttgtc aatggcgaag ataaggaaat tgttgacggt aaggttttga aataatctca
284461 ataactcttc ttccatattt tcttcccaat atacataaga gtcaaacaaa acgaattttc
284521 aaaagaaaaa agaaaaaaac cctgaagtct acttcatgat taccccatac ttacgcgtgg
284581 tttaattcta tgtaacgatt aacgtccatg taatcattat atatatatat attgtaataa
284641 tctctctaat tgagtatcac aatctgctgc ggttactcta acaatatttt gcataaactt
284701 gattcttctc ttcttatttc atgtttcagt ggggcatttt ccattgtact tttgcaacaa
284761 tagcgaaaaa aacaattttc cgtaaagaga agcgtcagtc ataaacggtg tatgttaccc
284821 gaactggaat gaattttatc ttaagactgg aaaacaattt aggatagaac tgaagatagt
284881 gcaacacgtc tggtgatatc atgtgctttc aagcaggatt tgtcacagtg ctttagaaac
284941 acaaacaaag gaggtatata gaagttgcag ttgctagagt ttgttttctt acctaattct
285001 agatcaattc ttttttctga aaaaaaaaaa tggctactgc gttatatact gcaaacgatt
285061 tcatattaat ctcgttgcct caaaatgctc aacctgttac cgcccctggc tccaaaactg
285121 attcatggtt caatgagacc ttaatcgggg gtagggcatt tgtttctgat ttcaaaattc
285181 ccgaattcaa aattggctct ttagacacat tgatagttga atcggaagaa ctgtctaaag
285241 tagataacca aattggggct tctattggca aaatcattga aattcttcaa ggcctcaacg
285301 agaccagcac caatgcttac aggactttac ctatcaataa tatgccagtt cctgaatact
285361 tggaaaattt tcaatggcaa accagaaagt tcaagttaga taagtctatc aaagatttga
285421 taacattgat ttctaatgaa tcttctcaat tagacgccga cgtcagagct acttatgcaa
285481 attacaacag cgctaaaact aacttggctg ctgctgagag aaagaagacg ggtgaccttt
285541 ctgtcagatc cttgcatgat attgtcaagc ccgaagactt cgttcttaat tctgaacatt
285601 taactactgt tctagtagca gttcccaaaa gtttaaaatc cgatttcgaa aaatcgtacg
285661 aaactttatc caagaacgtt gtaccagcat ctgccagcgt gattgcagag gatgctgagt
285721 atgttttgtt caatgttcat ttgttcaaga aaaacgttca agaattcaca acagctgcta
285781 gagagaagaa attcattcct cgtgaattta actactcgga ggaattaatt gaccagttga
285841 aaaaagagca tgactctgct gccagtttag aacaatcttt gcgcgtccag ttggtaagat
285901 tggccaagac agcttatgtc gatgttttta taaattggtt ccacatcaag gccttgagag
285961 tttacgtgga atctgttttg cgttacgggt tgccacctca ctttaacatc aagattatag
286021 ctgtcccacc aaagaatctc tctaaatgca agtctgaatt aattgatgct tttggatttc
286081 ttggtggcaa tgccttcatg aaggataaaa aagggaaaat taacaagcaa gatacttctc
286141 ttcaccaata tgcttctctt gtcgacacag agtatgaacc atttgtgatg tatataatca
286201 atttataatc gatttataat actaacttag attaatatat atttctgttt tttttttaga
286261 attttcaact tttttattca tagagataat acactgtgat tgtgaatgtt tgaatagtaa
286321 tggaacataa tccgataaaa tatgcttttg atgaacgatt agacattttt caattttgtc
286381 gttgagttcc aatccttcct tatttatggt taacaaggaa agaggtggaa gttaaaaaaa
286441 tggaaattaa aaaaaaaaaa aaatcaaaaa aagaaaaata aaaatagaaa aattggcacg
286501 gaaatctaca ggatttagca ctagtagggg gtttattaag cactacaggt cgactttaaa
286561 ccagaaaaaa ttatcattca gggtaggtgc aaacttgtta aaatgcactg gaatataatt
286621 tcgaaagagc aaagtagctc ttctgtatcg ttaccaactc tagacagcag tgaaccctgt
286681 cacatcgaag ttatcctcag ggcgataccc gaaaaaggat tacaaaacaa tgagtcgacc
286741 ttcaaaatag acccatatga aaatactgtg ctatttcgca caaacaatcc gttacatgag
286801 acaaccaagg agacccattc aacatttcaa ttcgataagg tattcgatgc taacgccact
286861 caagaagatg ttcagaaatt tctggtgcat ccaataataa atgatgtttt gaatggttat
286921 aacggtactg taataacata tggaccaagt ttcagcggaa agtcctattc ccttattgga
286981 tcaaaagaaa gcgaaggaat tctaccgaac atatgcaaga ccttgtttga tacgctagaa
287041 aaaaatgaag aaacaaaggg agatagtttt agcgtaagtg ttttggcatt cgaaatatat
287101 atggagaaaa cgtatgactt attggtacct ttacctgaaa gaaaaccatt aaagcttcac
287161 cgttcttcaa gcaaaatgga cttagaaatc aaagatattt gtccggcaca tgtcggatcg
287221 tatgaagact taagaagcta cattcaggca gtccaaaacg tcggcaatag gatggcatgt
287281 ggcgacaaga cagagagatc aagatcacac ctagtttttc aattacacgt agaacaaagg
287341 aatagaaaag atgatatatt aaaaaatagt tctttatatc tggttgattt acacggggca
287401 gagaagttcg ataaaagaac tgaaagtacg ctatcacaag atgcgttaaa aaaattaaac
287461 caatctattg aggcgttgaa aaacactgtg cggtccttgt caatgaaaga gcgtgattca
287521 gcctacagcg caaaaggatc acatagttct gcttaccgtg aatcgcaatt aactgaagtg
287581 ttaaaagatt cccttggggg aaataggaaa acaaaggtga tattgacatg tttcttaagt
287641 aatgttccaa ctaccctatc aacactagaa tttggtgaca gtattagaca gatcaataac
287701 aaggttacag ataacaccac aggtttaaat ctgaaaaaaa aaatggatct atttattcag
287761 gacatgaaaa ttaaggatga taattatgtt gcccaaatta atatactaaa ggctgaaata
287821 gactctttaa aaagccttca caataaatct cttcccgaag acgacgagaa aaaaatgtta
287881 gaaaatacaa agaaagaaaa tatcaaacta aagcttcaat tagacagtat tacccaatta
287941 ttgagtagtt ctaccaatga agatcctaac aatcgtattg acgaagaagt ttctgaaata
288001 ttaacgaaaa gatgcgaaca gattgctcag cttgagttat cttttgatcg acagatgaat
288061 tccaattcta agttgcagca agagttagaa tacaaaaagt caaaagagga agccttagag
288121 tctatgaacg ttaggctact agaacaaatt cagcttcagg aaagagagat tcaagagctt
288181 ttaactacta acgccatctt aaagggtgaa ctagaaactc acactaaact tactgaaaca
288241 cgcagtgaaa ggataaaatc tttggaaagt tctgtcaaag agctttctct taataaatct
288301 gcaatcccat ctcctagaag agggtctatg agctcgtcat caggaaatac tatgttgcat
288361 atcgaggagg gttctgaaat atcaaatagc ccttggtcag ccaatacttc ctcaaaacct
288421 ttagtatggg gcgcgagaaa ggtttcttct agcagtatag caaccactgg atcacaggag
288481 tcttttgtgg caagaccgtt caagaaggga ttaaacctcc attcgataaa agtcacttcg
288541 agtactccaa aaagtccctc ttctggaagc tgactataat taagttcgat aattgtacga
288601 tacaactgtg tagtatcttt gtaattataa tcatgatgat aacgctaata atttgtacgt
288661 ataatgctga ctgaaagatg tacttttctt ctaccgtttt tcttcggcgg ctattcgttt
288721 acaatgattt ggaaaaatga gaaaaattga aaataaaaaa ttctgctcga tgagatgaga
288781 tgaggttatg atatatatgt aagaattcct caagaagagg ttgcaagagt ctgcagacat
288841 tatcatggca gcaaatagca atagtagagt tgcatcaaac catacttcta aaaaacaaaa
288901 ggttaggagg aatatacatc cattcacgaa taacactcgg attaaaagag ctagtaaaat
288961 cgtaaagttt aatgattcag gcgagggcga ccatgtttca gaccaacgtt cgaacaagga
289021 aaatgtcctt acttataaat ctttgaaaag tcgggcaagc gatttactca aaatgagaga
289081 aacacttccc gtttaccaac acaagcgaga aataatgtca tatattgaaa gcaatcccgt
289141 taccgtcctt attggtgaaa caggttctgg taaatcaaca caaattccgc aattcgtatt
289201 agaaaaatta tatgatacga agaagcatgg gtcgattgct gtaactcaac cccgtcgtgt
289261 tgcggccatc aatttggcta cacgtgttgc tcaagaacat ggttgcaaac tgggtgaaca
289321 agtaggttat tctgtcagat ttgacaatac gactactaca agaacaagac ttaagtatct
289381 gactgacggt atgttactta gagaacttat gatgaatagt gaccttagag aatacagcgt
289441 catcgttatc gatgaagcgc atgaaagaac tgtgcttaca gatttgatat tggggttctt
289501 aaaatccttg atacaagggc caagacctga tttgagaata attgttatgt ctgcaacatt
289561 gcaagccgaa aaatttagtg agttcttcaa taatgcccca atcttatttg tagaaggaag
289621 aaaatttgat gtcaaacaat actacttgaa ggcgccaaca gatgatatag tagacgctgt
289681 catcaggtgt tgtatacaaa taaaccaagg tgaagaactg ggagatatct tatgtttttt
289741 accgggccaa gaagagattg acaaagcagt gactataatg gagaaaattg caaagtatgt
289801 ttcagatgag gccccagtac cattaatagt tccttatcct ttatatgcag ctcttcccgc
289861 ggtccaacag tccttggtct tcgctccgat aaagggtttc aagagaaaag tcgtctttag
289921 taccaatatt gcagaaacat ctgttaccat atccggtgtt aaatttgtcg ttgattctgg
289981 tcttcgaaaa gtcaaagttt ggagacatca gctgggatta gccactctac ttaccgtacc
290041 catttctcag gcaagtgcga tgcagagaag tggtcgtgct ggtagagaaa gtgaaggaaa
290101 gagtttcagg ctttattgtg agtctgatta tgtgaaatta cctaaacaaa gtgaacctga
290161 aatagccaga agtgacgtca catctcctgt gttaatgttg aagagatatg gtgttgatga
290221 cctgctaaac tggacctggt ttgagaaccc tggaaaggaa gctatagtaa tggggcttca
290281 ggaactttat gaattgggtg ctcttgacac tcgtggaaag ataactaaac ggggtcaaca
290341 aatggctctg ttaccgctac aaccgcattt aagtagtgtc ttaattaaag ccagtgaagt
290401 cggatgtttg agtcaggtca ttgatatcgt ctcttgcctt agtgtggaaa atttactgtt
290461 gaatccgtca ccagaagaaa gagatgaggt gaacgagcgt cgtttgtcct tatgcaacgc
290521 tggtaaaagg tatggtgacc ttatcatgct gaaagagctt tttgatatct atttctacga
290581 actagggaaa agtcaagatg caagctctga aagaaatgat tggtgtaaag gattgtgtat
290641 ttcgatacgt gggtttaaaa atgtaattcg tgtcagagac cagttaagag tttattgtaa
290701 gcgtttgttt tcttcaatca gtgaagagga tgaagaatcc aaaaagattg gtgaagatgg
290761 cgagctaatt tcgaaaattt taaagtgttt cttaactggg tttatcaaga atacagctat
290821 agggatgcca gacaggtctt atagaactgt ttccactgga gagccgataa gcattcatcc
290881 atcatctatg ctatttatga ataaaagctg ccccggtata atgtacacgg agtatgtctt
290941 tactacgaag ggatatgcca gaaatgttag taggattgaa ctttcatggt tacaagaagt
291001 tgtcactaat gcagccgctg tagcaaagca aaaagtttct gattcaaaat aagtcaccta
291061 ctcttagcgc atttttattg tatataaagg catttaatgt aatttataga gcattataaa
291121 tcgtaacaac tactgcagta tgagtttcat ggattcattt ctcaatatct tatgaatata
291181 cacaggtata tatgtatatt catgttaaac gcctttcgaa ttgttcgttg gctttttttg
291241 tgaaattatc tcgggaaaag ggcgaaatta tattattttg ccgttgacat tttgaaaagg
291301 aataaaagat catgaaaaaa ataagaaagg caattcgacg catttctctc agcaagctat
291361 tctttacttt tgaagaacaa aatattttag caaaaaggtt aagacaatat agtcggaagc
291421 agttctgcgg gatctgaagg aattgcggaa taatgagatt tcacgatagt atacttatct
291481 tcttttcttt ggcatcgctt tatcaacatg ttcatggtgc aagacaagtc gttcgtccaa
291541 aggagaaaat gactacttca gaagaagtta aaccttggtt acgtacggtt tatggaagtc
291601 aaaaagaatt agtcactcct acggtcattg ccggtgtcac tttttctgaa aaaccagaag
291661 aaacaccaaa tccattgaaa ccttgggtat ctttagagca tgatggtagg ccaaaaacca
291721 ttaaaccaga aatcaacaaa ggtcgaacca agaagggaag acctgattac tcaacttact
291781 tcaaaacggt aagttcccac acatattctt atgaagaatt gaaggctcac aatatgggcc
291841 ctaatgaagt ttttgtagaa gaagagtata ttgatgaaga tgacacctac gtctccctga
291901 atcctattgt cagatgtact cctaatcttt acttcaataa aggtctagca aaggatatcc
291961 gcagtgagcc attttgtacc ccttatgaga attctagatg gaaggttgac aagacttact
292021 tcgttacttg gtatacaaga ttttttacag atgagaattc cggtaaagtt gctgataagg
292081 ttcgtgttca tttgtcctat gttaaagaaa accccgtaga gaagggcaat tataaaagag
292141 atatccctgc aacttttttc tcttccgaat ggattgataa tgacaacggt ctaatgccgg
292201 ttgaggtcag agatgaatgg ctgcaggacc aatttgatcg taggatcgtt gtatcagttc
292261 agccaatata catatcagat gaagatttcg atccactaca atacggtatt ttattataca
292321 tcactaaggg ttcaaaagtg tttaagccta ctaaggagca actggcttta gacgatgcag
292381 gtataacaaa tgatcagtgg tattatgttg cattatctat ccctactgtc gtggtggtat
292441 ttttcgtctt catgtacttt ttcttatatg tcaacgggaa aaacagagat ttcacagatg
292501 ttactagaaa agctttaaac aagaaacgcc gtgttttggg taagttctcg gagatgaaga
292561 aattcaaaaa catgaaaaat cacaagtaca ccgaattgcc atcttataag aaaaccagta
292621 aacaaaatta gattcccttc gaagtatgca ttcacccttc ctcgagaggg ctgtttttat
292681 cttccgtcac actaatagaa aaccactcta tccagttttt tttgttactt aacttatctt
292741 aactcgatat tgtataaata ctgaagtcca tatacttctt tttttctcct ttggatagta
292801 aatacggtaa attaaaatta gtgtaaactg aacaatatta acatatataa atcatctgta
292861 cgacaatttg ataccaaata aatagagaat gcatcagcat cctccagggt tcaaaagaaa
292921 acgctggatc ttgcttcttt tcctttgatt tctccttata tccatttctg tcttgcagca
292981 acttcacata ttttttccag tgtaatgacc cttggatcag gcttaaaatg acgctcaacc
293041 acattatcat ctccttccac attcctgcta agtaagcttt cttcgtcgcc ctcgctattg
293101 tccacattat cttcatcttc atcatcatct ccgccgacgt cttcaatgta gtagaaaaag
293161 ggttccaaca ccaacataat tttccagaag ttgttcgtgc cacaattagc aaacaagaca
293221 tctacaaggg caggtaggta ttccaattca atgtactcct ctgcgcaaca aacaaattca
293281 tctaattcgt aatcttgctc atcagcagat aatgtagaat acatttctga taacaacgtt
293341 aattctttgc taattgtttt tggaatatct tctcgagctt gccataacag cttttgcgct
293401 ctttccagtc tttcttggct aacggcatca tccttgctct ctttttcgcc tttatcacct
293461 tggacatttt cggagtcttg tagagaaggc aagaatccgt tcttttcgct tttgaccata
293521 agctcattgt attcgttata gagggagata attttcatca taggcttgta taattgctga
293581 cagactttca tttccgagta aggtacaatg actttttcca aatagtgatt gatcagtcct
293641 tccatgaagt ttgcccaaat tgacgaaaat acataatcct cgtcgtaagt cgattccgta
293701 aaatcttggt tgatgttatg ctgtatgatt tgctctgtaa gagttgggaa aaggttttta
293761 tggcttttga ccatttcatc tctcaaagca gtagatccag cgctatctgc tcctttagta
293821 gaattttcca aactattatc tgttgaagac gcctctgagt tcttttcacc atctgtctta
293881 tctagccagt attccggacc acccttttca gacaatgtca ccaataaaag gaagagtttt
293941 actttaaccc acgggtttag cgagtttaca taggcgtccg taattttgct aacatcgata
294001 tttatttttc tatggatgca tttgataaat ttttcaatgt aatgtgattt tttcaatccg
294061 tatttttcat tcagatatcc aaccgaagtg attacgtcgt aatttgtatt ttccatgttc
294121 gtatgcttca aaaagttgaa tgttaacttt cgtctatttc cataatgtct ttctcttttc
294181 tcctcacctt tcttctttct tctaatcttt ttttcttttg aagcacccaa tttaagacat
294241 cttttacagg tacagtcctt taacgatggc tcgttggccg cttgcttggg caataaatct
294301 ttagccatct tctttggcgc gctatactag gcttgattta taatgttagt tattccaaaa
294361 atgtgaagga aattgatcaa ggcaagctct aatgatgatt attgacccat gcaacaaaaa
294421 aagtttgaat tctcttaatt ttccagatcg caagttagta gtcaatctgc taactttcgt
294481 tatatttcaa aaaagtaatt gtacaaaaaa agtcaccaaa aacgaggact tttttcactg
294541 cgttaaagat tagatctaca taatgaatac tcaattcttt acttaatttc gctctacaaa
294601 atagaccatt taggaaagtt gggttgcttc catcatgtca aagtcgtcct catctatata
294661 agtacacaga acagtgcgat cgttgaattg cgtacccggc aattcttcca ttgcgtgttt
294721 tgctgcctcc aaggtcttga acttgatata aatattaccg gctccggaag ccaagttttc
294781 aaaattaagt ctgtaatcga cgccgggttg gcatatttta atcgtatctg ctcccgcgat
294841 actatacttt aatgtttctt taatttctgt gataaaggtt tcatctttca aatccaatgg
294901 atcaagacaa tttaagagca acaaaactct cgattcaaca cgaacagatt gggtaaccag
294961 atttggcagg ctttgaaacg taatccatga agtaacttgt gatatctttc catcatttgg
295021 cttgaaccat ttgtatggtt ttaatttatc aagaatatcc tgagtgacga cttcaaacga
295081 taatagaata catttagtga attcggattc tttgccagtg ttgtttgtat tggacgaaca
295141 tttgtaaaaa agtggcttag cggtaccgtt tgttacattc aatgacgaaa aaagctcttt
295201 cattctataa tcttcaccct cgcctatatt ttccaaattt tccaatgcaa ttaccgtacc
295261 cctgcaaaaa tcgaccagat gatcaagttg ttgaacataa tcattaggtc ttctccattt
295321 taagtcgaaa gtaccaagct tcgcattaaa gaatgatcga caggccaaaa ccatagtgct
295381 acagatctga gaactaaact caacaataat atggtccggc cttccttcac caatataaaa
295441 gttggaaatt ttaaagtcct ccgcattact ctcagttttc tggagacctg aaataaaatt
295501 ttccagcaaa tctttcaatc ttgctacaat gctggggtcg ctgctttgag acaagcccga
295561 aattacaagc cttgaatttg ccttggatga ggccatgttg tagtaagccg gagaatcgaa
295621 tgatgaaccc gggtacatta cattttggga attatagttc atgtcatatt tattagtttg
295681 caactgcctt ttatcacggt cgccattgaa tttagaacct tcgttcttcc tttggtaatt
295741 gaaacgatcg tagtttccgt ttccatttct tccccttcta tcgaaccttt catttcttcc
295801 tcttctttca tcccgttgcc tattataggg attgttgttc cattggggcc cagtattgtg
295861 actactatac cgattctccc tgttatatga tcttcccgat gcatcccgat aactttgacg
295921 atgaggacct gcccttgttt gttcataagt cgttcgattc gtgctcatag taattattga
295981 cgatggtcct ctgttattag aatgtgaaac gtttctactt tttggcgctt tcggaagctc
296041 accgtcactt ttttgcctct taaaatgtgt atctataact gcattatccg tgttgaatct
296101 tttgttctca atcggcacaa catccttttc tgattttcct atagactcca ttattttgga
296161 tctcaaatcc tccagtctct tttcatcagc catctccgtg tgcttgtttt ctgtgtcaat
296221 taactttcct tttctacttc ttttatatta gcatgtacag tttaatttct catctcgaat
296281 tttttcagca cttgctaatt aggcgcgcgc ctcaaatata taatatcgaa cacgctgtta
296341 taaaagtgat ccattctaca gcgtaatatt aacagtatcg ctcctgcagt attctggcat
296401 tattagtgca aataagtacg catattacca tgcgaaacgt tttaaggctt ttatttttaa
296461 cagcttttgt tgctataggg tctttagcag ccgttttagg tgttgattac ggtcagcaaa
296521 atatcaaggc cattgtggtt tctccgcaag ccccattaga acttgtgctc acaccagagg
296581 caaaacggaa ggagatatct ggtctttcga taaaaagatt accaggttat ggaaaggatg
296641 atccgaatgg gattgaaaga atctacggtt ccgctgttgg cagtttagca acaaggtttc
296701 cccaaaacac attgttgcat ttgaaaccgc tacttgggaa atcactagaa gatgaaacca
296761 ctgtaacttt gtattcaaaa caacaccccg gtttagaaat ggtatcaaca aatagaagta
296821 ccatagcctt tttagttgat aatgtggaat atccattgga agagttagtg gcaatgaatg
296881 tccaagagat tgccaataga gccaattcac tgttgaagga tagagatgca agaactgagg
296941 actttgtaaa caagatgagt tttacaattc ctgacttttt tgaccaacat caaaggaaag
297001 cacttttaga tgccagttca ataaccacag gaatcgaaga gacatatctg gttagtgaag
297061 ggatgtctgt tgcagttaac tttgtattaa agcagcgcca atttccacca ggtgaacagc
297121 agcattatat cgtatatgac atggggagcg gttctattaa ggcctcaatg ttctctatat
297181 tgcagccgga ggacactact cagcccgtta caatagaatt tgaaggatat gggtataatc
297241 cacatctagg tggtgcaaag tttacaatgg atattggcag tttgatagag aataagtttt
297301 tggaaacaca cccagccata agaactgatg aattgcacgc taatcccaag gccttagcaa
297361 aaatcaacca agcagcagag aaggcaaagt taattttaag cgccaattct gaggcaagta
297421 ttaacataga atcactgatc aacgatattg atttccgtac ttctataact agacaggaat
297481 tcgaagaatt tattgcagac tcgttattgg acattgtcaa acccataaat gacgctgtta
297541 caaaacaatt cggtggctat ggaacaaatt tacctgagat aaatggggtc attttggcgg
297601 gaggctcttc ccgaattccc attgtgcagg atcaattaat caaactcgta tccgaagaaa
297661 aagtgttgag aaatgtcaat gctgatgaat cagctgtgaa tggtgttgtt atgagaggga
297721 tcaagttatc taattcgttt aagaccaagc cgttaaatgt tgttgaccgt tctgtaaata
297781 cttattcatt caaattatca aacgaatctg aactgtatga tgtgttcacg cgcggaagtg
297841 cttatccaaa caaaacatct attttgacaa acacgactga ttcgattcct aataatttta
297901 ccattgactt atttgagaat ggtaaattgt tcgaaactat cacagttaat tcaggagcta
297961 taaagaattc atattcctct gataagtgct cgtcaggagt tgcgtataac attactttcg
298021 acttgtccag tgatagatta ttctctattc aagaggttaa ctgcatttgt cagagcgaaa
298081 atgacatagg taactccaag caaattaaga acaaaggcag ccgtttggct tttacttctg
298141 aggatgttga gatcaaaagg ctttctcctt cagaacgttc gcgtttgcat gagcatatca
298201 agttgctcga taaacaggat aaggaaagat ttcaattcca agaaaattta aacgttcttg
298261 aaagtaactt gtatgatgct agaaacctgc taatggatga tgaagttatg caaaatggac
298321 caaaatccca agtagaagag ttatcggaga tggttaaagt atatttggat tggctcgaag
298381 atgcatcctt tgatactgac cctgaggata tagttagcag aattagagaa attggaatat
298441 taaaaaagaa aatagaactt tacatggatt ctgcaaagga acctttgaac tctcaacaat
298501 ttaaaggaat gcttgaagaa ggccataagt tacttcaggc tatagaaacc cataagaata
298561 ccgttgaaga atttttgagt caatttgaaa ccgagtttgc ggataccata gataatgtta
298621 gagaagaatt taaaaagatt aagcaaccag cgtatgtgtc gaaggcgtta tctacatggg
298681 aggaaacctt aacctctttt aaaaattcca ttagcgaaat agagaagttc ctggcaaaaa
298741 acctatttgg cgaagacctt cgtgaacatt tatttgaaat caaattacaa tttgatatgt
298801 atcgtacgaa actagaggaa aaactgcgtt taataaaaag cggtgatgaa agtcgcttaa
298861 atgaaataaa gaagttacat ttaagaaact tccgcctaca aaagagaaag gaggaaaagt
298921 tgaaaagaaa gcttgaacag gaaaaaagca gaaacaacaa tgaaacagaa tcgacagtaa
298981 tcaactcggc tgacgataaa actactattg tcaatgacaa gaccaccgag tcgaatccaa
299041 gttctgagga agacattttg catgatgaat tatagaagaa tctttataat atatagcact
299101 agatttattt tccgatatca aattcagtta cttatataaa gttaaccact tgttacttct
299161 tttttcgcag cgataacggt aactattatt gttagctctg tttatgcgga aaggttatat
299221 gatcttcggt gcaagattta gtgccctatt tagtcacccg gacatctatt gtttgatggt
299281 ggggcaattt cgagagatga cttatttaag cataagacag ataataatgc atagaaggtg
299341 gatatacgta atgcacatta atattatagt ggcactgaag caaaattcag aaaaatttaa
299401 aaacatataa atataaaaga aaaaaaagaa gaatttcgag actgctacga aaagtgaaag
299461 taataacaag cgtgcaaaag ttcataatat ccataataga ttggacatag aaattaccgc
299521 aaagcgcaaa gagttatcat tcgtacgatt ttgaaaaata atatatttgc tgggggaaaa
299581 aatgcaactg gaagccactc atcagaaaga aaaccacctg tctcctttgg ctagcttcat
299641 ttttccagac ttcagggcat tgttcaacat agggtttaat ttatattcta atataaacta
299701 caaagaagta gatattaatg gatttgaaat ttacattgtc gaacaatggg ctgcccagag
299761 aaaaatatca actctaatca cttcatatac gggcaactta caagacacca tatctgcagt
299821 agaggttgct cttcccgaag atcctgagga atggccatgt tgtttgaaga aataccatga
299881 agaattgttg aagttttcta gtccaaaaaa gactgccaaa ggaactttat ttgttacaaa
299941 cctttcttct ttcaaatcta cgctaaactt attgcatgtt gagtgtggta atctaaagaa
300001 aatctggaaa aacttcaaaa ccaactacga cctaaagaga ttacattgtg gtggtcgttc
300061 agctcagctg ttaaaaaaga cacctagtgc ctcaatagcg aagtttgcac agttatataa
300121 atttccgaat tcagcttttt ctcatgaaat aacgtcggat ttccaacaac cttctcttca
300181 gaatgacaac agctcaataa gtagcataga aaatattcct gttaatcatt gccctgtggt
300241 agaactaact accctcgtgc aaatatcact tagttatttt gcgctgtttg aatacaagaa
300301 ggagagagat ggtctcttat gcaatggaac gaaacaatcc cttgaaaaat ggtgggaaat
300361 atatgggaaa cgataccacg gcattgataa gccgaagaat gaaacgatcc ttggtccgac
300421 tacggtggca tcactactta gtcttgtatt gacttgttac ttcaaattaa tggtagaaga
300481 ttgcatgtca gcaaaagatc cgtttgatga agaagagttt tattctggtc tttatgcatt
300541 tcaaaagaaa tacggcctat ccaaaaacaa taaacagacc tccttagacg aactaacaat
300601 tgataaatta tttgaagtat cttccaagac ttcaaacaaa gatattttca agtttaaaaa
300661 ggttgtgaag tcaactgttc aagacatgac tggcaaagga aactttatgc atctatccaa
300721 tgagatccta acaactgatt tagataccct ggtaaagaat atacacggtg gatcccttgg
300781 taagctctgg aaagggagaa gtgcttcgag aaaggaaaca tgcatggttt gggaaagaaa
300841 aacctttcta agtttcaagt ttgaacgtgg agatccatcc ttacaattgg aaaataatga
300901 gctgttttat ggtacgagtg tgccaagtga acagttaacg acttccaata aggaggacag
300961 tgatacgcaa cccacaaaga gaaatagtat atatgatatt gccaatggct ccaaatcatc
301021 gctatctatc tcatccatgt tctgtaatta tgatgaaacc cgttacaaaa gtaccaacaa
301081 ccttaataga gcctataggg gggagtattt taggcgcaat tcgatcccat tttgtaacga
301141 tggtatacac gatactaaaa aaatatctgc tgatcttaat aagatagatg gattgtatcg
301201 ttgcaattca tattctgagg tacaaaacgc aatagagctg tggagcttgc cattcgattc
301261 atcagtcatc agattagcaa gagacttact taagatacaa agtctaatgt cagttcaacg
301321 tcagctcgat gaaatacgtg acggatatct gggaaaaaat tcacaaagat cataccagaa
301381 tgatctgatg tttagacaaa gcttgaacaa attgcaggaa atgtgtgaga gatgtaagag
301441 aggttctaac gaatttcact gggaatatgg taacatgcaa aacaaacagc aaattttgga
301501 gagtgagaaa aaagatatga aatcactttc ttcgaaactg aaatataacg ttcgtatcct
301561 agatagacgt gtaagagatg ttgaagccag cgtagatcat tttgatcgca agttagagga
301621 tgttagaaaa aagcttctgg agcaaaataa tagtaaagac atatctatgg ccttagaaag
301681 tccttgtgat aaatttgaat ttgacagttt tatggactct atagtgcagt cccaacagac
301741 taaatatgaa gggctgtgtt ttaaaatttt agacaagaaa agtcttcgaa agttaaaaaa
301801 ggaattctgg aaatggagca cctggacatt cgataccttc ttatacaaaa ataggcccaa
301861 taaggagaaa gatacactat gaaagcttcc tcatttcgtt actgctgttg cagatctatt
301921 aaatcagaca atgcataaga tacactaatt tcctggagag ccatatactt atagatatta
301981 taaaaattcg taattttaag aattctgcca tttgagggat gcatatttaa tttcctggga
302041 gaactgtata tttatggttg atctttgggg acagttagct attttcttct ttcacattat
302101 agatgtcaca tagacttcct tcctttttac ggaataagcc cactgaaatt tttaaggaag
302161 ctccagctca ttatgctctc gttcttctgt tctgagtttc gagaaatact acgaattatt
302221 gagaaaatga aaatcaacta tcatttatcg atcagtacat ataaggtgaa aagagaaggt
302281 aatagcatta tgtaaaatat tggtgtccta tattctcgag gaaaacttct agtggattcc
302341 attgttgatg aaggctataa cattaggtat acagaatata ctagaagtgc ctcctcgagg
302401 atctaggaat actcaaaatc tatatttcta cataaaaata ttacatatta ttcctcgttc
302461 cgttttatag gtttcattat tacattatct atccttgcat ttcagcttcc cctgacttcg
302521 atgacagctt ctcataactt atgtcatcat cttaacaccg tatatgataa tatattgata
302581 gtatgactat tagttgatag acaatagtgg atttttattc caacagtttc atacttattt
302641 aaatgtttag gttgatatat tggtaatgat atgttatctt actctgagat gcaacatata
302701 tgctacatac tgaactcatt tatccaatat taaattaaga gattggtgaa ttttgaggta
302761 tttgttggca gatctaaact tcatcatgct cttctttttc tatgtatcta atcttgtatt
302821 ttatcttcat agaacactgt tatctctgct cttttcagat atagtcgtca ttgtttgagg
302881 tgatctatcc tattttaaaa cgtgaatatt ccaagatgaa gcggtggctc aatggtagag
302941 ctttcgactc caattaaatc ttggaaattc cacggaataa gattgcaatc gaagggttgc
303001 aggttcaatt cctgtccgtt tcattttctt tttttgccat acatttagcg ctccacactc
303061 taaataaagt atttcttctt ttcttgaaaa tgatgtactt aggttgatga aatagcctca
303121 gttactggaa tttccttacc tttgtcgtgt tactgatagt atatcttaat cattatttct
303181 tgtttcaatc tggattttga tttgcgcggc atatcgttac cgccttttgc atattataaa
303241 tggcttatat aagtatacag caactttcat atattataga taggtaattg cctccacatc
303301 gaatcacata ggataaagaa ccgacttcct gccgcgaatt tagagttttc acgttatgtg
303361 accatctcaa tttttagaat atttgctaag ccacttgcta ttaaaacttc atggacaggc
303421 cccagtatta tcgcaataat actggaaaca tcaacgaatg ctataataat gcgcatttac
303481 tttgggcaaa agaactattt aaaattacgc attacgtagt ttattttgac attatgatca
303541 taaacatgcg caaatcctaa gatcgtgaat tacctctact gcgagaatac aaattataac
303601 atatgactaa cgttacacaa cattgtatta catttctgac taatttgaag tctgggagtt
303661 aattgtagta gcctactaaa tagcgcggtt atttataaag ctaacattac catgttacat
303721 gacatgctat ttctagcgag gtaaaagcat tgctccggct tttcgaagat aagtattcct
303781 tcaatttcca aatgtcacaa cataaaattt tgatttgcgt tatctctcgt tctctttaat
303841 cactacaata gcatcaacca agtcaataaa acatgttgtg aagagactac gcagacgtga
303901 cggtcatcta gcaactctcc atcttttgat gcagccatcc acagtttatc gtgagttatg
303961 gcaaaatcca aaaatgtacc gtaccatttc ctctttaatc ctgtattcaa taagcaagtt
304021 ccccatttca attgatctac acatcactgc gcgttaaagc gcacctaatt tattcggtag
304081 gaaacagaaa tagtctgcaa agtcattcaa gcacctttct ttaccaaatg aaaggattta
304141 atagtaccta tgaaacaata gttcgaactt ttgccatttc ccggtttttt tggccagctt
304201 gtataaaagt gcaccttacc cttatattgg gctcttattg aatgccttcc gaagaactga
304261 ctattcaaaa aatagaaaca agtacgtcaa taaaaaattt tgcaattcta cgaataatta
304321 ttcctgtttc tttaacctgg taaaaaaaag tacaaacact taagcttttt gaaacagctt
304381 tattttgctt cattaaatag ctaggataag aaatccctca tccgaaaggt tttgtatcta
304441 actaccctag agaacatttg tcctgatcag gttcatttgg agtttatatt ttttagaagc
304501 tcaaagtttg ttggactcat taccatggaa gaaaaaaaga agatactacg aaatattggt
304561 ttctcaggtt aaataaggga caccattttc ctattaggct agtcgagctt agttcttcta
304621 atttcttcag atcttctata atttcctatc ttctacctga tgtgtgcatg atatatctat
304681 gagctcctga tattgcttgt tttactttag cttgcatgac ttgcaataat ctaatcatat
304741 atgttcccga ttaatatact gtgcacaaat tgcaggacat ataatttttc cgtggattat
304801 atcttcgatt aacgtccgcg ggtctcataa aaagcaaacc aacttcgcaa ttccctagaa
304861 atacctcaat agaaagttat ttgtaatgag attagtaatg agattagcaa tgagattagt
304921 aatgagatta gtaatgagat tagtaatgtg attagtaatg catagcggta taaatggtag
304981 tactaataag taagatagta taccagttat aataaatagg cggcgatgct tcaaaactaa
305041 tttttgacgt ttttaagaat aaagccttta ccagtggcat aaatcagtag aattctaagc
305101 aaacaaagtc gatatgaata cttcatcaag aataacttac tttatcatcg gtggtagccg
305161 tggaattggt tttaatttgg tcaaaatttt aagcgcttct acgggcaata cagttataac
305221 ctctattcgt ggatcacctt cattacccaa gaacaaacaa gtggaagatt tagcaaaaat
305281 caggaagaat atccatattg tccaacttga ccttacaaag gacgaaagta ttggcaatat
305341 tgcggacgag atcaagaaaa cgccattctt cttgggtatt gatattttta tcgcatgttc
305401 tgcagtatct gattcttatt acaaggtcct ggaaactccc aaatcagtct ggctcaacca
305461 ttatagcaca aacgctctgg gtccgatact agcccttcaa aaagtttatc cactgcttct
305521 tttgaaaaag acgaggaaga tattctttat ctctagtgtt gcaggatcta tcaatgcgtt
305581 tgtaccactt tctgtttccg cttatggtca atcgaaagct gccttgaatt atgcggtaaa
305641 gacgctcagt tttgaattga aaccggaggg ttttactgtc gttgcttttc acccaggtat
305701 ggtatctact gatatgggcc aatatggcct tgatcatttt aaagagaaga atatagacat
305761 cagcggcgta aatattatca caccagaaga aagtgcctct gcgctaattg atgtcttccg
305821 aaaaatttta ccagaagata atggaaagtt cttcaactat gacggcagcg aaggcgtctt
305881 ttagataagt gcaaatttgg ctacttatat acaactcaga tacggaatat acctttgtgt
305941 aatacacttt tttattggta ggtgctatat gatgtgactt tgcttttgcc tcacgcccct
306001 ttaagaaggt attttgtggc atcactttgt atgctgatct tttaacgctt aaccagattt
306061 gaaactatct ctattatgtc ctctgatttt aattaggatg gtatataact ggtcctagaa
306121 ccgaagattc tgcatattcg ccgaaaacca tcccttaata ttatagacat aaattgccag
306181 tctgagaaga atccaagaat ctatttcata atgtacattc ctaaacattt tgagtccatg
306241 gaactctcaa ggtacaaatt atcaaaaaaa cccccgctag gaacactatt ctcctctaag
306301 gctagcaggc aaggtttctt cggatggaga acttcttcca ataaagatga ccccgatttt
306361 ggtatgtgcg catcacatat tccatttgta ttcgtggagt tcgataatgg agagcataaa
306421 cttattgcac atttagcacg gaagaataaa catgtggaaa tgctggaaag agttcaaaaa
306481 tgcttagtgg tatttcagag cgtcgattca tacatttctc cggcgtggtt cccaatgaag
306541 aaaaagaccc ataagttcgt accaacatgg gattttgccg ctgtgcacgt ttacggtaca
306601 ccaaggatta tccgcgacga taaagactgg cttattaata tgttatcaac tttgactgac
306661 caagaagaag agaaaagacc tgagggggaa aatgtacgaa gtaaagtgga gcgtttctga
306721 tgccccagat tattatatca atgctatgct tcaaaacatt gtcgggcttg aaatcagtat
306781 tacccatatt caatcaaagt tcaaattcga ccaaaataaa tcacagatta atgttgaagg
306841 catatgttga aaattcaaag aatttggtgg agaaagaggc caagaaatgg ctcgccttgt
306901 aaaagataac tatccaggta gcttataagt tttgtatttt ctctgcgcat taaatatcaa
306961 taattattta ttcgttttca ttcttttctt atcttatctt ttaatattga cttaacagag
307021 ggcaaggccc accgtgatgc agaaagaaca caaacgcaaa ggtttaccta ttccctgcag
307081 ttagaaaacc atgtttggag gaaatgaaga aagatattta cagttgagtt tacaacgaag
307141 tattatcctt tttaacgaac gctaatatca tcggtttctt catgtttata tgatgacgat
307201 tttcccaaat gtaagcaaac aaaggcgttt gctgataaaa caaatccgta aattagaaaa
307261 aaaaacaaaa aaaaacaaac agatatgggc tcatcaaccg ggtttcatca tgccgatcat
307321 gttaactatt cttcaaatct gaataaggaa gaaattctag aacagcttct gctttcatac
307381 gaggggctat cagatggaca agtcaattgg gtttgtaatt tgtcaaacgc ttcgtcattg
307441 atctggcatg cgtacaagtc attagctgtt gatatcaatt gggctggatt ttacgttact
307501 caagctagcg aagaaaacac actgatattg ggcccatttc aaggaaaggt cgcttgccaa
307561 atgattcaat tcggtaaagg tgtttgcgga actgcagcct ctacaaagga aacgcagatt
307621 gttccagatg tcaacaagta tcccggtcat attgcgtgcg acggtgaaac caagagcgaa
307681 attgttgttc caatcatatc caatgatggt aagacattgg gcgtcataga catagattgt
307741 ttggattacg aaggattcga ccacgtagac aaagaattcc tagaaaaact tgctaaatta
307801 attaataaat catgtgtctt taaataagag ttttgagaac gaacaagtat ttacgcacat
307861 aaccaatatt cccatgtagc tctcttgtca aatatattgt cggacgggca cgaatagaga
307921 taaacatcaa gaaagattga ggggcttcag gagatcattg gtgaagaaaa cattccctgt
307981 tcgccaaatt gacagctctc aatctttatt tgtaaccctt attgcaaatt tatggcatgt
308041 ttaccctcaa acaaaggata ttcagcattt attaaaaata tctttgcttg gtaagaaaaa
308101 aacgtcaacg aaaatgacgg agatatctga cggaaaaaaa aattgatttc gcccaggatc
308161 gaactgggga cgttctgcgt gttaagcaga tgccataacc gactagacca cgaaaccact
308221 taattgttga ataacggaca tctaaagtca tatctatagt gcagcaagtt cttcttcagc
308281 tcaccccagt ctcgctaaag gcatgcttac tttgccgtaa agaagaaagg aacgttcaaa
308341 atgtgtttga tgcgtaactg tgatgatttt ctatcattta cttgcatgat atcggtgaaa
308401 attctagcta gatttatcaa tgcatagaag cagtaagtga tgccacagat atgagctttt
308461 ctctgtggcg aggtctttga gaaattaagt ggcttgtaca gttttcacat gacgattgga
308521 aatgttgaaa aaagagccta aaaataggcc ttatcgaaca acattaaact aataatcttc
308581 tggatgcgat agtcttactt gataaaaatc attggcgata ttgtgttacc tggattatca
308641 agctcgccac taaaggtgtc tggatcctta ctcaatacaa agtccaagga aaggtgtgcc
308701 acaggaagag gtagcatccc tttatttctt ttcaaggaaa gaagcatttt caatcacata
308761 tgtatacaat agtcttccgt gtggctgcac cgcaccacct tgcaggtccc gtgtatgtag
308821 gagtcgcatg cgaataaaaa attgagaaag atcatggggt tttttgttca cgcgggccgc
308881 agttgtggct cctctgtcac ttttttgccc tctgctaagg gcaaaaaaga aaaaaaaacg
308941 caacgagaaa attaaaagtg tggcatttcg acatctatcg ccattcgtgc ggccatttct
309001 cgaaacaacg ctaaactttt gtttcgactg tgaggcccta gaacagttcg attctgatgt
309061 aggcaatgga agaaacaatc atatataact acagaaccta atgttacatg cttgcatctc
309121 tcagctcccg cgaattttca agtgagactt aatggtagcc atctagtaac tcataaatca
309181 acgacattat atatcatcaa ctacaatgca ggcaaaccat tccgtcagtt acctttacga
309241 atcaagtact tcaaagaggt caaatgggct cttttctcaa acacaaaagc aaggaagttt
309301 tcaaaaagct ttaagtcaaa ctcaggaaga aatagaagat gaagacctga tggtagacct
309361 caacacagga tctttaactc ccgttaagtt aaaatattgg actcaaatga gtgctatgac
309421 ggaaaaattt ggtaaactgt gagaccaatt ttggcggtaa tttcgtttag ctgttttatt
309481 ttcacatttt taattgtcaa tgctggaggt tgttaaagtt tggctagctg ttctgaacaa
309541 tccttgtata ccggtgagac tttttgttat agatattggc gatattcatt ttttaggaag
309601 gtgtttttat agatttttca attttttttg tgtagatgca tgttttgatt acttatgcat
309661 agtacgaatt tttagtttat taagctatag aggttttttt ttttttcacc tctttaccac
309721 aaatttaata gctattgtgt agaataactt ttaatggaaa acatttgcag tattttagta
309781 tttttctacc tgtttattgc aagtaagggc agcattatcc tgataggagt agaggttaac
309841 cgcacatcgg aatgagactt ctccaagaac gttctcaaag taaaacattt agcattagga
309901 aatttctttg gtcgattatt agacaaagat tagattgtat tatgttctga tgcttagtta
309961 gaacggaaag tgttacccat cttgcaatca ccgtgacacc ttaaatattt gccgtaagcg
310021 aagaaaaaaa gcatgaaaaa aaaaagcata tttatgctga agtcatctac aaatgaccac
310081 cgcttttgga cctgaagagg agaagaaaat aacatatcgt agaacagtct ttgttaacca
310141 aaatatttta gctttgattc cggactatta gtacattgaa ttttttcagg tactaacaat
310201 gtttggcaac aatagaccaa tgtttggagg gagcaacctt tcctttggat caaatacgtc
310261 atccttcggt gggcaacaat cgcaacaacc aaactctctt tttggaaata gcaataacaa
310321 caacaattcc accagtaaca atgcccaatc aggatttggt ggattcactt ctgccgctgg
310381 cagtaatagt aacagtttat ttggaaataa caatactcaa aataatgggg catttggcca
310441 gtcaatgggt gccacccaaa actcaccatt tgggtcgtta aactcctcaa atgccagtaa
310501 tgggaacact tttggaggat ccagttcaat gggttctttt ggtggtaata ccaataatgc
310561 atttaataat aacagtaaca gtaccaattc cccgtttggt ttcaataaac cgaatacagg
310621 agggaccttg tttggttcgc agaataataa tagtgcaggt acttctagtt tatttggcgg
310681 ccaaagtaca agtaccactg gcacattcgg aaacaccgga agtagtttcg gaacaggctt
310741 aaatggcaac ggctctaaca tatttggggc agggaacaac tcacaaagca atactaccgg
310801 cagcttgttt ggcaaccaac aatcttcagc gtttgggaca aataatcaac aaggaagtct
310861 atttggacag caatctcaaa acaccaataa tgcgtttggt aatcaaaatc agctgggggg
310921 cagttccttc ggatcaaaac cagttggttc agggtcgctg tttggccaga gcaacaacac
310981 tttaggtaat acaaccaata atagaaatgg attgtttggt caaatgaatt ccagtaacca
311041 aggcagttct aacagtggat tgtttggaca aaactcgatg aacagcagca ctcaaggggt
311101 atttggacaa aacaataatc aaatgcaaat taatggcaat aacaacaaca gtttatttgg
311161 aaaggcaaac accttttcaa attccgcatc aggaggttta tttggccaaa ataatcaaca
311221 gcaagggtcc gggctgtttg gtcaaaattc tcagacaagc ggtagtagtg gactttttgg
311281 gcagaataat cagaaacagc ccaatacttt tacccaatct aatacaggaa taggtctctt
311341 tggacagaac aacaaccagc aacaacaatc tacaggtttg tttggagcca aaccagcagg
311401 taccacagga tctcttttcg gtggtaattc atcaacccag cctaactctc ttttcggtac
311461 taccaatgta cctacctcta atacacagtc acaacaagga aatagtcttt ttggtgccac
311521 gaagctgacc aacatgccct ttggaggaaa tcccactgca aaccagtcag ggagtggaaa
311581 cagtctattc ggaactaaac ctgcctccac taccggctca ttatttggaa acaacacagc
311641 ttctacgaca gtaccttcca cgaatggatt gtttggtaac aacgctaaca attcaactag
311701 cactacgaat acgggacttt tcggtgcaaa gcctgattct cagtccaaac ctgcattagg
311761 gggagggtta ttcggcaatt caaactcgaa ttcttccaca atcggccaaa acaaaccagt
311821 ttttggaggc acaacccaaa atacaggact ctttggcgcc accggcacga actcttcagc
311881 agttggttca actggtaaac tttttggcca gaataataat acgcttaatg ttggtacaca
311941 aaatgtacca cctgtgaaca ataccaccca aaacgccctt ttgggtacaa cggcagttcc
312001 ttccctacaa caagccccag taactaatga acagcttttt tccaaaatat caatccctaa
312061 ctctattaca aatccagtta aagcaacaac ttcaaaagtg aacgcagata tgaaaagaaa
312121 tagtagcctc acgtctgcct atagacttgc cccaaagccg ttatttgctc cctcttcgaa
312181 tggcgatgct aaatttcaaa agtggggcaa gacactggaa agaagtgata gaggaagcag
312241 taccagcaat tctattacgg acccagaatc aagctatcta aattcaaacg acttgttgtt
312301 tgatccagat agaagatatt tgaaacatct ggtgattaaa aataataaga acttaaatgt
312361 cattaaccat aatgatgatg aagcaagcaa agttaaatta gtgacgttta caacagaatc
312421 agcttcaaaa gatgaccaag cctcatcaag cattgctgct tcaaaattaa ctgaaaaagc
312481 acattctcct cagactgacc taaaagatga tcatgatgaa agcactcctg atcctcaatc
312541 gaaatctcca aatggttcca cctctatacc aatgattgag aatgaaaaga ttagcagcaa
312601 agttcccggc ctattgagca acgacgttac ctttttcaag aataactact acatttcacc
312661 ttccatagaa acgcttggca ataagtcatt aattgaactt cgtaaaataa acaacctagt
312721 cattggtcac agaaattatg gtaaagtcga gtttctggag cccgttgatt tgttgaatac
312781 tcctttggat actttatgcg gggatcttgt cacctttgga ccaaaatcat gttcaatata
312841 tgaaaactgt tccataaagc cagaaaaggg cgaaggcatt aatgtacgtt gtagagtgac
312901 tttatattcc tgttttccta ttgacaaaga aacaaggaaa cctataaaga atataacaca
312961 tcctctactg aaaagaagta tagccaaact aaaagaaaac ccagtgtaca agtttgaaag
313021 ctatgacccc gtaacaggca cctatagtta caccatagat cacccagttt taacttaaac
313081 cggaataatt tttgtagaga atccttgtat cgtctaagta gtctagatgt tcagctgata
313141 gattttcgtt gtattgtata tataataatt gtcggaaaac aaaaatactt aattgtaatt
313201 gtgtgaccga aaatgcctga tcaacagcca tggcacattt gaatgggatt ttgaggagac
313261 aaaaatgaag aggttctata acctttgtag aagaacattg acctcttttc aatgaaggtt
313321 ggtggcatcg ccagatgcag aaaggttgtc tcatgaaata aaaacggaca gaccatgaag
313381 gctaaaggaa aaaaataaaa tgccatctcc tagaatcgaa ccagggtttc atcggccaca
313441 acgatgtgta ctaaccacta tactaagatg gcaaacaact gtgaagtttt tggttacatc
313501 tgcacatctg gttgaataaa tattatgtac tctttgcttt tttatgttaa acctacaagt
313561 ggtgactgta aagaagcatt acaacgtaga actgataaag gggagaaata tgtgagttgt
313621 tagataattg ttgggattcc attgctgcta aaggctataa tattggtata cagaatatac
313681 tagaagttct cctcgaggat ataggaatcc acaaaaggga atcgatagtt ctacataatg
313741 ttattatttt atcttccttc cttttatatg ttgtcattca ttatcctatt acattatcaa
313801 tccttgcatt tcagcttcca ttagatcgga tgactgtttc tcaatcttta tgtcatcttc
313861 tcacaccgca tgtgataata taatattaaa tagatgatat tagagttcaa ttccaacaaa
313921 aggggagtag ttacataagc tttccgtaat ggtgaattta tagcagtttc cttctcgatg
313981 aaaggaaggg aaagaattaa atatactcga atgcttgtac cactccattt ccccatttat
314041 cacatttaaa gttacgagta aaaaagtgac cgatatagaa tgtctgatga aagagcaaat
314101 gaaagaaaca tcaagaaagc atattgaaat tagcaagtga aagcaaaaaa agtagatgag
314161 taagcattat aatgcgtcca gtctgacttt tttgttggaa taaaaatcaa ctatcatcta
314221 ctaactagta tttacgttgc tagtatatta tcatatacgg tgttagaagc tggcgcaaat
314281 gatgagaaat agtcatctaa attagtggaa gctgaaacgc aaggattgat aatgtaatag
314341 gatcaatgaa tgttaacata taaaacgatg ataataatat ttatagaatt gtgtagaatt
314401 acagattccc ttttatggat tcctaaatcc ttgaggagaa cttctagtat atctacatac
314461 ctaatattat agccttaatc acaatggaat cccaacaatt acatcagaat ccactgagtc
314521 ttcatttttt cctatttttt gaattaattt ttgttcgtat ccattgggct ggcgagcaag
314581 tccatcaaat aaaaaggcgc gtaattcgct tcgtttcgtg tcttcgaaaa tgaagaccag
314641 ttttcctcct taaaagtact ttaattcgga gagccgatta tataaagtga aagacttagt
314701 acttcgttag ctcatatcgt tttcttattt tgaaataggt tatctataga atactttatc
314761 aagttatcag gttctttccg gaaaaacatc tcataaatca tccctggaaa aatgtctagt
314821 caaacagaaa gaacttttat tgcggtaaaa ccagatggtg tccagagggg cttagtatct
314881 caaattctat ctcgttttga aaaaaaaggt tacaaactag ttgctattaa attagttaaa
314941 gcggatgata aattactaga gcaacattac gcagagcatg ttggtaaacc atttttccca
315001 aagatggtat cctttatgaa gtctggtccc attttggcca cggtctggga gggaaaagat
315061 gtggttagac aaggaagaac tattcttggt gctactaatc ctttgggcag tgcaccaggt
315121 accattagag gtgatttcgg tattgaccta ggcagaaacg tctgtcacgg cagtgattct
315181 gttgatagcg ctgaacgtga aatcaatttg tggtttaaga aggaagagtt agttgattgg
315241 gaatctaatc aagctaagtg gatttatgaa tgaataactt atggcatggg agggtacata
315301 tgagcgcctt ttttttctcg ctttgggcag ctcatatcat gttccctcac tagctaataa
315361 tataatgaat tttttagaag gagcacgatt atataaaaaa aataccactt atgttgctac
315421 ccttatatac gaatttataa tacttaatga cgcttcaatg acgcctgatg tcaaatgctt
315481 ttggctccca gtgaaattgc cacacttcct tcttctttcc gaactttata gtatcatcga
315541 aaaatacaag ttggcaaagg tctattacaa tcgcggaacg tacgatgttc atacggtttc
315601 agcgaatagt cttgtaatat ccggaagcat gcctaccggc attattatag gtagttcatc
315661 gcccttggac tatgtagggg tacaagtaaa taggcaactt gaaatggatc tccctattga
315721 atgaaacatt taagggtgcc caacccttaa gttgatagag ctactaccgt tcttttaggt
315781 ttaacagttt ctccaataaa tttggcaata tgcagggatc ccaaattgaa atttctggcg
315841 gaatgtatat attagacttg cagctgagtt ttatcgcgta cactattcta gggactttgg
315901 acctaactct gacaacaaaa actcaagtaa aaaaaagctt acatttttaa atgatgagat
315961 ctaatatttt gaaattatta caacggacaa gtaggagata tgtatcctca aaggattttg
316021 agcctgtgat agggtctaat cctaagaaac aaacatctag actaatggtc ggttctgtgg
316081 gtgttatgat tccagttcta ctttatttgt tttataagaa cgatagcaaa catagtgaaa
316141 ttaaaaagat ataccaaaat gagaaaaaaa tttaaaaagt tgttatataa gggttttcgt
316201 atataacaca gaatggtaaa ccgagtcacg aagctcaatc tttttttttt atgtctttct
316261 ctaacgtttt ttcgtctata ttcaaaaaaa ataaagttgg taacatataa tgcatatatt
316321 catttgatct aatcgcttgc tttttatttc agtagcattt tcgtattgcg tcgcgaccag
316381 agaagtatga gcaccagagg taacacgtat atacatttat acataaatat atctatttag
316441 tttcctttct tggaagcttc agcagctgct acatttccag gttgattctt ctcatcaaaa
316501 tatttctcca ggtttttgac ttgcttttgt aggccctcca gagaaatttg ctttttcctt
316561 agttcctctt gaagtttggt ggaatcagct tcatttgagt ctttcttgct gtttgaggaa
316621 ggtttgttca atttttgctt ttcttgttcg ttgattaagc cttggtattt caccagtctc
316681 ttgacaatag acatgacagt tgggatacag atagaaaagt acaatatgaa cccggaaata
316741 tacatatttc tttgattgta cgctcttgat gctagtgcct gtattggagt tacagcagat
316801 gacccgattg agccactgtt gtcgttgtgg tataatgaaa cacgaatttg agaccttttc
316861 catgaatcaa taaacaacag gccaacaaga caacccgtta taaagattat agtttttatt
316921 tgctgcttcg ctgtcaattg gttataggtg ctaaaaatac ccctacggat ccggaatggc
316981 aaaggcaaaa cgaagatgaa gagcattacc atctcaacag tgagcaataa aaataatgtc
317041 gtaaagtata aactcatcgc aatattattt attcttctcg gttttcagta cttgccactt
317101 tgcgaaagga tagcagaaag gagcgttgca atgaacgaat agctttaaac cagaaactat
317161 acaaggtccc acttggcata tatttctatt tttgcactgc gccagagggt ttagtagcgc
317221 cccctttatg ttaacgtatc ctgtgatata gcatgcagct gcgggttaca tgtaaattgt
317281 tcagggcata agcagtacgt atcgaggagg taaaagacgt tgcaagtagg tagatagtac
317341 aatatagata agcccaacag tttgcgtacg ccttaaaagt agtggtgttc tgcgtttatg
317401 ttctctccct tcttttctat ctaggttttt atggcgcact taaaatattc tgctgcttca
317461 acgggcggcg atctacggag aaatttttgg cataaagtca aacttagaaa gagcacataa
317521 gccataactt ctttttgata tgtgaaacct agcccaggtt gtcgttagta gtacctggcc
317581 ctttaaatat atttttgtac tatcgtatac ttgtataact attcatcatt ttctggtttg
317641 gtagtccgca ttttttcatt tgatgactaa gttgtacgta ttgctacact gagtttatcc
317701 ccttacttcg acagtaaatt gagagaataa aagtgagaag tgtagagaag aaaaagatta
317761 aaaatgagca ctgataactc acaaaaggat gaaggtgttc ctttgctttc cccttactct
317821 agtagccctc aactaaggaa aaagaagcgc aatcaaaaaa gaagaaagga caagtttgtt
317881 ggtcacttga agtcagactc acgtaggcca acgcaactgc tgcatgataa tctgcaacac
317941 aatcacggcc agattactga tttcgaccag atcgattcct ggggcatgct gcatgaatct
318001 gattctacaa gtaatgatat aataaaaagt gaggatccat cgctcaaggg cgcgttcatt
318061 gatcatagac cttcaatgag ccaacctagg gaggggcctc aaagtgtatc aagcacagtt
318121 caaccacagc caataatgaa gttttcaaca ccaagttaca agaaacccgc agggttaaga
318181 ccctctgatc agaatagatc attagtatcg gacttatccc cttcagagct tgaatcatgg
318241 ctgaagagaa ggaaatctgt tcataagagt tttgttgacg aaaactcccc caccgatagg
318301 agacaatcga acgcgaataa tgatgtcgtg attgatgttg atgcgttaat gaaccatgtt
318361 aacaacaatg caagtactgg ggttaatgat aacagcaaga gaagaaagaa aaagaggggt
318421 tctgatgata gtagcaacaa aaattccaaa tccacatcca gtgattcaaa cgatgaagag
318481 gatgagtata actcaaggcc atcttctagt ctttcttcaa ataactcttc tttggatgac
318541 gtttgtttag tgcttgatga tgagggtagc gaagtgccaa aagcttggcc tgattgtact
318601 gttttggaag aattttccaa ggaagaaaca gagagactaa gaagtcaagc tattcaagat
318661 gctgaagctt tccacttcca atacgatgaa gatgaggaag atggaacatc aaatgaagat
318721 ggaattcttt tttcaaagcc aatcgtaact aatattgatg tccctgaatt gggaaacaga
318781 agggtaaacg aaacagagaa tttgaagaac ggccgtttaa ggccaaaaag aattgcgcca
318841 tggcatttga ttcaacgtcc aatggtcctt gggtccaatt caaccaagga ctcaaaatca
318901 agaattcaaa gcggattaca agataactta ctagtcggca gaaatattca atatcctccg
318961 catattattt ctaataaccc agaacatttc aggttcactt attttagggt ggatttggac
319021 tctactgttc attctccgac aatatctggt ttactgcaac ctggtcaaaa atttcaagat
319081 ttatttgtcg cttctatata ctcccaagat aatagcgctg gtcatatcaa gacacatcca
319141 aattctccaa cacctggtat aaaagcagaa actgtatctc aactccaggg attgacagct
319201 aaaaaccctt ccactttatc gtctatgtct gtggcaaata tagaggatgt tcctccattc
319261 tggttggatg tcagcaatcc tactgaagag gagatgaaaa tattaagtaa agctttcgga
319321 attcaccctt taactacaga agatattttt ttgggagaag ttcgtgagaa agtggaacta
319381 tttagagatt attacctgat ttgttttaga agtttcgata ttgtagcaga aaagcatgtt
319441 cgtcggagga gaaaagaaaa gcaagaatct gctaccttgg atcatgaaag tatttcacgt
319501 cgtaaatcac aagcctatgg tgctactatg tcaaatgaat caaatgcaaa taacaataac
319561 agtacaagca atgcaagtag gagcaaatgg cttccatcga ttttacgtgc acgccgtcgg
319621 tcatctgcaa atagaacaac caatacatca tcatcaagct ataaacgccg tgtcaaaagc
319681 gaaaagaaaa agatggaaga gaacgaaaaa ttcaaaagaa aatcaggaga caggcacaaa
319741 ccacgtgagg gagaattaga gccattgaat gtttacatta ttgttttcag aactggtgta
319801 ttgacgtttc attttgctcc cacaccacat cctattaatg ttcgaagaag agcaagacta
319861 ctaaaggatt accttaatgt tacctctgat tggattgcgt atgccttaat cgatgacatt
319921 acagacgcat ttgcccctat gatagaactt atcgaagatg aagtttatga gattgaggac
319981 gccattttga agatgcatca gtcagatgat tctagtgata gcgattctag cgatagtgat
320041 tccgattcgg gcgctagcga tgaggatgca tttccgttcg atgtctattc taaaaagacg
320101 tcctactcta gtgcaaaatc tagtgtgagt tcaagaagta tgagcacttc tgaagcgtca
320161 ttcaatgcaa atttgatagg ttggaagaga aaaggagata tgttgaggcg gattggtgaa
320221 tgccgtaaaa gagtgatgag tatactaaga ttgctaggat ccaaggctga tgtgataaaa
320281 ggatttgcca aaaggtataa tgagcaatgg gaagcttcgc cacaatctga aatcgcaatg
320341 tatttgggtg atattcaaga tcatattgta accatggtct catcgctaaa ccattatgaa
320401 aaactgttaa gtagatcgca ttcaaattat ctggcacaaa tcaacattga tatgacgaag
320461 gttaataatg acatgaacga cgttttggga aaaattacca tactgggtac tattgttctg
320521 ccaatgaatg tgattacggg tctgtggggt atgaatgtta tcgtgcccgg acaatacagg
320581 gattcgttga catggtttat aggcattgtg ctttttatgt gtatgctagc atgttctgca
320641 tatatgtata ctaagagaag attcgggttt taatttaagt gttttttcgc gcattagcgc
320701 ttgcttttcc ttcgatttta attatcagcc taaattattg ttgtctttcc cgaaggatag
320761 aattgtaaat tatcagcgcc gtatcgtata cttgtggtga taaatatctt taatctattt
320821 atgttttttt tttttttttt tttcgtgtct ggtttctaca tgtttgtgaa cgttctgcat
320881 atctttatgt acgtacacag tatgttagta tgcacttata ctatacaaag aataagggag
320941 gtgaggttaa tcaataaggt taacgtaaaa catttattat tttcatcacc aaactgttgg
321001 aagttttgaa ttggttaatt atcaaggatt tcattgttag ccaaattttc cttggcgaga
321061 tcttgtttct ctttctggag ttgctgtttt tgttcttttt tgtccttgtt tatttgtttt
321121 tgcttttctg aatcaatttg tggtttcaaa tcgttctcca aattctttac ttcttgttgc
321181 tttgcgactt cattattgaa cttttcttta ggtactttag cttgttgtgg ttgcttattg
321241 ttagtcgcat cagctgcacc gccggctgca atattggtat gatcgcttgc acttgcagaa
321301 acatcagaag aatggctttc tagcttgatc tcagtttctt tattcagatc agaataggca
321361 acttttataa cgaaataaac gccacataac agtataatgt atactataat ctttttcata
321421 ggggtagtca gataaccgcc ccttcttctg gaattatatt tgcttcctgt tttataacga
321481 ggtaaaagat cttttttcct tctgatatcg ccctgcatat tttctataat tatgaatcac
321541 tttagtttga tttatatttg ctcagaatac cctagcttta tctatatagt actactactt
321601 tggaggggag gaacgtatgt tggaaggcaa tagcactctg gtaaagtgct aactcttaat
321661 gttaatgacg aaatcacttt ttttgccttt ctgaaagatt ggaagactgt cactgagaaa
321721 ttcgctattc ttttcttttt cttcgtgttt ttttttgtta gaatactgca cagcttgcta
321781 tcccgctgca cagcttgcta tcccgctgca caacatgaaa ttgctcacgt cgtgccaaat
321841 tacatatagg tgcttaccct gtttatattt tttgccttca tagcggagtt tttaagggta
321901 gcccttatgt ttttagcgtt catttgaacg aatggctaac gctaaacgga gaagagagga
321961 aaacaaggcc gctggcgtta ttgcgcgtaa aaacaggaga taagcactgt ttaacataca
322021 tttcattgaa agcttaaagc cgcaaaagat gaagggtttt caaaattttc atctcttgca
322081 gtataaggat gcagtgaatc tatctacaga cagttgataa aaacgtctac cttgcctagt
322141 gtacccagct gctgtcaact tctttcctta gcgcgtaaag agctatgttt tcgataaaag
322201 atgcaacata aatgctacga tgtaaggcac ccaggacctc tgaaggcaaa gaagttgtga
322261 aatttgaaaa ataatcgctc aaaaaggaat aattgtcaag cgtaacgatt tttttgattt
322321 tccgaaatca ggggagggga aaagaaaagg ggaaggggtc tcctcacagg tattgtgagc
322381 tccaagcaat cattttgcca gcactaggaa ataataaaat gaaagaaaaa aacatacata
322441 gaaagtgccg ctccggggca ttttgagcgc ggcaaaaaaa gcccgaagat ccgttcctcg
322501 aaggaacggc aaccgcacac caagaaaaag ggaaaaaggt ggggttggct gtaaagtacg
322561 agcgcgggga cggatccgta acaatttcta tgtggggcca gcagccggct gctggtgggt
322621 actgttgtac gaagcggttg gtagcgatga cagtggccag ggctgctagg catggtgccg
322681 tgaaaaccca gcgcaaatgt caggctgcag gaaccggctt tctcccacga ggtttcactg
322741 ctggcggcgt actggtcatt tttagaacct gaaaacccga gctagaacta ggactcttga
322801 gcaataaggt ttgcgcattg ctattctccg gataaaccaa acccaccctt ttaagagcgt
322861 ttaacaaagg tctcttatct atcaaaagta ttatggctat ttctgggatt ccgcttgcgg
322921 gcctttctac cctcttgatg ctacacatgt ttcccttaga tgcatgagca tacctgtagg
322981 tacttaaatt ttatttttat gcatcttatt tctgtctaaa tttgtatata acaagcaact
323041 gcagttctgt gatgtgtttt tcgcaactgg tcaacaggct taagaatttt tccgtctctt
323101 tccgttttat ttccagagaa ttaacattta tagagaaaag aattaaaacg tgaaatttcc
323161 tttttgaata tttaacgcct ttatcagttc ggcttttttt tcttttcttc ttattaaaaa
323221 caatataatg ctagtcttcg gacctaatag tagtttcgtt cgtcacgcaa acaagaaaca
323281 agaagattcg tctataatga acgagccaaa cggattgatg gacccggtat tgagcacaac
323341 caacgtttct gctacttctt ctaatgacaa ttctgcgaac aatagcatat cttcgccgga
323401 atataccttt ggtcaattct caatggattc tccgcataga acggacgcca ctaatactcc
323461 aattttaaca gcgacaacta atacgactgc taataatagt ttaatgaatt taaaggatac
323521 cgccagttta gctaccaact ggaagtggaa aaattccaat aacgcacagt tcgtgaatga
323581 cggtgagaaa caaagcagta atgctaatgg taagaaaaat ggtggtgata agatatatag
323641 ttcagtagcc acccctcaag ctttaaatga cgaattgaaa aacttggagc aactagaaaa
323701 ggtattttct ccaatgaatc ctatcaatga cagtcatttt aatgaaaata tagaattatc
323761 gccacaccaa catgcaactt ctcccaagac aaaccttctt gaggcagaac cttcaatata
323821 ttccaatttg tttctagatg ctaggttacc aaacaacgcc aacagtacaa caggattgaa
323881 cgacaatgat tataatctag acgataccaa taatgataat actaatagca tgcaatcaat
323941 cttagaggat tttgtatctt cagaagaagc attgaagttc atgccggacg ctggtcgcga
324001 cgcaagaaga tacagcgagg tggttacctc ttcctttcct tctatgacgg attctagaaa
324061 ttcgatctct cattcgatag agttttggaa tctcaatcac aaaaatagta gcaacagtaa
324121 acccactcaa caaattatcc ctgaaggtac tgccactact gagaggcgtg gatcaaccat
324181 ttcacctact accactataa acaactctaa tccaaacttc aaattattag atcatgacgt
324241 ttctcaagct ctgagcggtt atagtatgga tttttctaag gactctggta taacaaagcc
324301 aaaaagcatt tcctcttctt taaatcgcat ctcccatagc agtagcacca caaggcaaca
324361 gcgtgcctct ttgcccttaa ttcatgatat tgaatctttt gcaaatgatt cggtgatggc
324421 aaatcctctg tctgattccg catcatttct ttcagaagaa aatgaagacg atgcttttgg
324481 tgcgctaaat tacaatagct tagatgcaac cacaatgtcg gcattcgaca ataacgtaga
324541 ccccttcaac attctcaagt catctccggc tcaggatcaa cagtttatca aaccctctat
324601 gatgttgtcg gataatgcct ctgctgccgc taaattggcg acttctggtg ttgataatat
324661 cacacctaca ccagctttcc aaagaagaag ctatgatatc tcgatgaact cttcgttcaa
324721 aatacttcct actagtcaag ctcaccatgc agctcaacat catcaacaac aacctactaa
324781 acaggcaacg gtaagcccaa acacaagaag aagaaagtcg tcaagtgtta ctttaagtcc
324841 aactatttct cataacaaca acaatggtaa ggttcctgtc caacctcgga aaaggaaatc
324901 tattactacc attgacccca acaactacga taaaaataaa cctttcaagt gtaaagactg
324961 tgagaaggca ttcagacgca gtgagcactt gaaaaggcat ataagatccg ttcattcaac
325021 ggaacgccct tttgcttgta tgttctgtga gaaaaaattc agtagaagtg acaatttatc
325081 acaacatcta aaaactcaca aaaagcacgg tgatttttga aaaaaataag gtcaaaagca
325141 aataaaagca agacaagcta cggtatgaca agttttcgga gaaataatat tctttcttcc
325201 tcagtttaca aaacaagtag gttggtcatt tcattcggat atattctaag gaatgaaatg
325261 aacattggtg tttgtttcta atataatctt aagatatttt aaattgtttc tttccttttt
325321 tgcctttcta actattactt caacttcttt tccgtatatt tccgtttttt ccatttggca
325381 gattaaaaaa attgtgcacg ttctggtttt aacgtataga cttctaatat atttctccat
325441 acttggtatt ttttattcac tttttttata catatttggt ttttttatac aatatcaaaa
325501 atcaataata attaatttaa taacaagaat atgttgctgt gatgactctt aatatacaat
325561 tgggaagcat tcaaggattg gtacgacgtt tgctttctga taattaaacg cttggcgttt
325621 aatctttttt gccgattaat aatattatta ttaccctctt atttattagc attgtcttcc
325681 gtactaaaag gagtagggaa aaaggcgaag tagagtgaca cgtccattac ccagcgcttc
325741 ataagaatcc atcaggtata ttaaattgtg atgggagaac aaaacaaatt gtactatgat
325801 gtcgagaaat tggtgaattc tttgcaggaa agttttgacc tggattgcgc gcaaagtgta
325861 tcacttttca ccagtaaatc aaggagcaat gaggcttggt tggaagagct agagaataaa
325921 ttcaagttaa aagatgatgt tgaacttgat gatgtggaaa atttaagagc cgaaattgac
325981 atgaagttaa atatgttgga ggataaagta agctactatg aaagacttta caaagaactc
326041 gaagagttcc agaatgaaat aaaaattaaa acagttgtga ataacagaag acaatcgcga
326101 actccaaaat gagctatcaa aaacgataga tcgattagga tgactttgaa atgactccgc
326161 agtggactgg ccgttaattt caagcgtgag taaaatagtg catgacaaaa gatgagctag
326221 gcttttgtaa aaatatctta cgttgtaaaa ttttagaaat cattatttcc ttcatatcat
326281 tttgtcattg accttcagaa gaaaagagcc gaccaataat ataaataaat aaataaaaat
326341 aatattccat tatttctaaa cagattcaat actcattaaa aaactatatc aattaatttg
326401 aattaactta taaagtgtta gtggtacgga aagtttccaa agacttggtg atcttagcac
326461 ccatggtctt ttcaccttct ctaacccaga ctcttgggtc gaagaacttc ttgtttggct
326521 tttctggacc ttctgggtta ccgactgggg acattatgta gtccttcttg ttcaagacgt
326581 agtctctgat accagtcaag taagcgtatt gacagtcagt gtccaagttg accttgacaa
326641 caccgttgtc aataccagtg tggaattctt ggacagtaga accggaacca ccgtggaaga
326701 ccaagaacaa tggcttttct tccttgcaac caacttgttc tctggtgtac ttttggtgtt
326761 cagccaagat ttctggtctc aaagcgatgt caccagcgta caaaccgtga cagttaccga
326821 aagcagcagc aatggagaag tttggagaga ttgggtgcaa agccttgtag acgttgtaaa
326881 cttgttctgg cttggtgtac aagtcttcct tgtcagcgtt ttcgttgtta acaccatctt
326941 cttcaccacc ggtaataccg atttccattt ctaaccattg gtccatagcg gccattctct
327001 tgaagtactt gacacaagta gagatgtttt cttcatcggt ttcttcagac aaatccaaca
327061 tgtgggagga gaataatggt tcaccgtgtt ccttgaagta agcttcatca gcttccaaca
327121 taccatcgaa ccatggcaac aacttcttgg cacagtggtc agagtgtaag acaactggga
327181 taccgtaagc tggagcaatg gatctgatgt agtgggcagc ggcaatagca cccttgatgg
327241 aagcattttg accttcgtta gagataccct taccagcgaa gtaagcagca ccaccgttag
327301 aggtttgcaa aatgattggg gacttgctgt ctctagcagc ttctaaagca gcgacggcag
327361 tagaagaaga ggtgacgtta atagctggaa tagcgaactt gtgttcctta gcgtaagtga
327421 ataagttgtg gacatcttca ccaacgatga caccggtctt tctctttaag atttgttcaa
327481 cacccatttt gaatatgtat tacttggtta tggttatata tgacaaaaga aaaagaagaa
327541 cagaagaata acgcaaggaa gaacaataac tgaaattgat agagaagtat tatgtctttg
327601 tctttttata ataaatcaag tgcagaaatc cgttagacaa catgagggat aaaatttaac
327661 gtgggcgaag aagaaggaaa aaagtttttg tgagggcgta attgaagcga tctgttgatt
327721 gtagattttt tttttttgag gagtcaaagt cagaagagaa cagacaaatg gtattaacca
327781 tccaatactt ttttggagca acgctaagct catgcttttc cattggttac gtgctcagtt
327841 gttagatatg gaaagagagg atgctcacgg cagcgtgact ccaattgagc ccgaaagaga
327901 ggatgccacg ttttcccgac ggctgctaga atggaaaaag gaaaaataga agaatcccat
327961 tcctatcatt atttacgtaa tgacccacac atttttgaga ttttcaacta ttacgtatta
328021 cgataatcct gctgtcatta tcattattat ctatatcgac gtatgcaacg tatgtgaagc
328081 caagtaggca attatttagt actgtcagta ttgttattca tttcttaggg cttgcgtcag
328141 cttgatgagg atttgtgata gtagccgttg gaggcatgaa gggcattgga aacatgggga
328201 aaggaggtat accgaaaggt aacggtactg gtggcactgg cgtaccgccg ttatttacag
328261 aagttggaag gctggtattg ttgttcaagc cagcggtgcc agttggatcc atcaacttca
328321 ttttcttagt ttctggctgg ttgccatctt tagagcttcc gtgtagttcc tcttgtttct
328381 tcaaaaacgt ttcgacctcc ttttccttgt cctggtcggg tactaaagaa tcgagaagga
328441 tatcgcgggt ttcgcaattg gggcatacaa agtcgctctc taccagtgca ttttccagcg
328501 cctcttttga gaaatctatg ttacagcact tgcttgtctt taccggctgc ctcaaaagac
328561 cacctgtcaa gggacatttt aaatcgtcag gaagatcttt gaaatggcct tttctccaaa
328621 tggtttcatc accatcaatt tgacggttct ctcttttcct ttggtagtct tcccatgatt
328681 gtttgtcttc aacttgtacc acgaacttgc cttcgtccgt aatcataatc tttcgctgag
328741 ccatctcttc cggtgtcatt gtctcgggat ctatttcaat ggattttaaa aacttctttg
328801 gaatacctgt ggttcttctg attctttttc cttcaaaatt tggatcgctg ttagttggac
328861 aatttttaat ccagtggtct ctacccccac aacgatagca catataacct ggtggcggtg
328921 ggccttcgtt ttcttgtgca gaattcttat tcgtctgtga cttgaaaaaa acaggtgtgg
328981 ctgcagacat ttcttcttgc gtttgttccc attgattttc ttgtgtggca aacatactag
329041 caattctttc ttcttccgtt gtaccactaa cattagcagt ggttgtagca gtgtgttgtc
329101 tcttttgcaa cactcttggc ctaccagtaa cataccttgt tgcgttccca agagctgctg
329161 ctcccacatt ccctttaagt cgactgtgta cggagaatga tttaattgct ggagatcttt
329221 ttactatgac actagtagat ctaggtataa caaaggcatc atcgtcgtat tcctcttctg
329281 tatctgggtt gtaaattttt aattggaaat ctgtgccgtc acctagtttg ttctcttgaa
329341 taatttccct tttcaaatca aatactgtca ggccggtacc atcaaataaa attcttgatg
329401 tgtttcgttg agacttaaag cggtaaaata tcgtgctact catgttacac tattccagtc
329461 tctgccgata tgatgagagc taccgaaatt tcagtaccct cttgattgtt cttgcttatt
329521 ttatgttggc cataaacttg gttattaaca atatgcttga tattcatcat cattgtatta
329581 actttcagta aagttacccg cctgaattac aatgttgtga cataatataa tggcataagg
329641 aaggttattg caccagcaat ggattaaggt agttatattt accgcttata cactacatga
329701 taatgaatat atcaagtcga tcatcctttt ttatgtttta aaatacttta catacataac
329761 tgtgttttta ctttatctaa aaaaagagtt gttatgaatt tgtgattatt tatatttcca
329821 aatatttatg atctcaaaac gtaaaaaaac ataaaaaaaa agtgttaacc aaagaaattg
329881 aagaaagata gataaataag ttccaaaagt tctatgaatt ttcaggttgc atggcagata
329941 atgtcttctg ctaggcaaat gtcaaacatg aactgaattg tcaatacaac ataatgttag
330001 cttcattatt gttgtattgc cgggtaagct aattttacta ataacaatat tttcttaacg
330061 ccttagaata ctttgtgaaa tattcgaccg aataaggaat aagtagaaga tgcacttaga
330121 ggttaggagg gggacacagg ctatcgaaga taacagtaag gataaatggc agtacccggg
330181 tattacgaat tatatcgtag aagtactata gggaatagtt tggtggatgc tcttgatact
330241 ttaattagtg atgggagaat agaagcgtcg ttagctatgc gtgttttaga gacatttgac
330301 aaagtggtgg ctgagacttt aaaagacaat acccaatcta aattgactgt gaaaggaaac
330361 ctggacacat atggattttg cgatgatgtt tggactttta tcgtaaaaaa ttgtcaggtt
330421 actgttgagg acagccaccg cgacgcctcc cagaacgggt ctggagatag ccaaagtgta
330481 atttcggtgg ataagttgag gattgtggca tgtaactcaa aaaagagcga gtaatatcta
330541 tgctatatgc ccggatgctt tgttgaccaa tagttacatt gaaatttctc tattatctcc
330601 tctcttctac cgcttttaat acaagctcta ggaacagtgt catgaaataa tgttttgtat
330661 tcttttatat tagggaactt gtgattcttc tgtttttgtt ttttattttt cctgtctgta
330721 cattcatgta ataataattt agatttaaag ttcaatcttt ttacttaaaa aacaaacgaa
330781 gatcatggtg ctaatattcg gatttgagtt gatcaatttt ttaaatgaag tattaattta
330841 cagtttatat attcactata gacctcgtaa ctcatctctt aaatcagtta aagtaaccac
330901 tttacttccg tttagaatcc attgatcgta tgcactatca aagctagata aaacgttgat
330961 gaccattagg taacattttc tctttcgaat aacatcaaga tcagcttgca ttaatatgta
331021 ctggtacagt acttctgcag cagccctctc gcttttgttc aacattctaa aacaataaag
331081 tttcttaaaa cactcccaat caccactccg tagattttgt gacagaatac tatccactat
331141 tttaatatct actgtacgaa gatatagctc gccattgtct gaatgtgcgt tacacaagcg
331201 cagaagtgtg ctgaaaaaat ctcgtgaata tatgtcttcc tgtaataata attggagaaa
331261 atttgttctt actgtgtcgg aaagacactc gtgacccaat ctcaaaacat ccaagacttc
331321 ttcaaacatt ctgaagtgga ttaaaagatt taaataatga atatgctgtt tttctttgaa
331381 gtcttgcagt tcttcaatct gaatttcttt taatgaatat tctgctgact tagatataca
331441 tttcaaagca aattcttggc tgttatttct atcaaataag agagataatt gataatagaa
331501 tgcagaatgc ctatatggaa ctgtaaaggt gcacaaaaga tctttccata tactatcacc
331561 gtgatagttt tcactcttaa ggtcttctaa gaatgtcggc aatttatcat tgatagcctc
331621 cggataatcg tgtagttgaa aaatttcata ggattgatcg aaattaccac aactaaataa
331681 cgtcatggca aacataaatt cttgcacctc gttgtggcgt aagtagaagg ggcattcaac
331741 gttctcgaga aagaacctta tattcttatg agatgtgttt tcaatgatat atgagcggaa
331801 aaacgtcata aagaaagaat tttcagtgat ggaagcattg taaacattag agtttaagga
331861 atcgatatag gcaatgagtt ggccgtagtt aaaaaatttg acaccgaaag agaattcaga
331921 agaatccttg agaagaactt ccgccaacag acacttatct tgtctataaa ggtttaacaa
331981 taaaaattgc ttataatgca aatccaataa tgtagatata tgctgtccga aaatttcggt
332041 atcaagatcg aacagaacga atgttaacaa tacttgtaaa gtaatacgat aatgtatgga
332101 aagtaactgg tgaagagatt ctagggaaat tatacttgtg aaaccatcga atttgattgc
332161 agagatgaaa tcctttttcc aaaatatacc aggcttcatt tggttattga ttaaatcatt
332221 taaaacaacg ggtatatcaa aagagtttaa ttcgtcgaaa agaatcttta gatttgtgat
332281 ttcaaattga ttttctaggc aatttttgaa aatgtccgta aatttttcta cggtagtcat
332341 agaatcaggc agctctcctg ttattatatc aagaaacttc ttagaaatgg atctaagaac
332401 atcatttgac aaagtagaag caaaaccatt caatgtcctt aaatacttga acaattcaga
332461 accatcagtt tcagagtgca tattataaaa ccaattctcc acagtagtat tcagcttgta
332521 aagggaatga ttatacggtt ggaaacaatt gacgagaata atttcatcgc cataaagtgt
332581 tatagaagaa gcctcgttga atgcggtttt tacgtctctc aatattgttt ctaaattagc
332641 caaatattct tcatcttcgt tatgagccat aataatctta ttttcactca atatttgctg
332701 tgcacgttca aaaatttggg taccatatct tgatttcaaa ttacagaaac ccctctcaac
332761 atctccagtc tttgtaacga tatccaaatc atgttcggat tgcaaatcta ctaaggattt
332821 gttaactgat tctatccatt catagttttt gaaactttca tcatttacgt ttagtatctg
332881 taacttgcta gcagtgccac ttttccataa aacgatcaaa tttaaataac tagcctcgac
332941 attcaactcc aatggtctcg ttagaactaa atctacaatt gaccaaatag cagaagctga
333001 aagattagtg gggatgttat tttgaaaagt ataagtcaaa ataccgcttg aatcaaccaa
333061 caaggtgccc atttgaaaaa gcccattttc caaaggcaac aatgtaacta gagtattgtt
333121 atacaaggaa aggtattccc ctacagcttc cacttttcta aaatggcttg ggtctgaatc
333181 tgactgtgaa accatatcat aatcttgtat taaagtaaat gaagttaaat cccaaatttt
333241 caagtggcaa ttctgagtca acacaattaa gtatctttca tggaataatt tacaactaat
333301 cacactatcg taatccgatt tagaactcct agaaaaaaat cgcgttaggc ttttcaagta
333361 tgaattatca ttgaatagta aaggctcgta atgtacgccg tcaacttttt ttaaacccaa
333421 caaaccgcca tcttccaaaa aaacaactga gaactggggt gatacataga aaaggaaatg
333481 aggaactcta actgtaaagt cgtagggatt ttggagatga aaccactctc cattgagagt
333541 gttggccgat gaaaatagga aacttagggg tagttgtaac gttaaaaacg aaccatcttt
333601 taagataaca ttaaccagta attgctgttc cacttcttgt atcgttaaag tgtatctctg
333661 attcatagaa gcatttggta agtgtatatt aattgtcttc ccatggtatg cgtcactcaa
333721 aggataaaat gtcaacaatg ttgatcttga ggaaaaatgg taacagatat actcagagtt
333781 actcaataac aaacaattgg aatattcact tccgtaaggc tgaggaactg gtgtagagat
333841 ggacttatct ccttctttca gcccgttatt attactgtta ttactgacgt ataaatcaac
333901 cgtattattg ggttcaggtt tttcataata ttggagcaaa tttgcatcaa ttcttgagag
333961 gcatgccata ataggtcagt tgtgtacgag tgaaattgcg acctcttgaa aaatgcttat
334021 gaacgttgga tttcgtcaat ttctacttgt ttctcagctt ctcatgctat ttcaattcaa
334081 tttttttttc acgtaattgg agaaaaagac aggaaaacaa aaaacatgaa agttctgtag
334141 ggtaatggaa aagaaaatat tgatgaacta tacatatcta cggcaattga taaacgtgtc
334201 ttaataaaat catagaataa ttaaaaacgt cctaatgcgt gttaagaagt aattaggaag
334261 tttagatacc tatagaatca aagaatagaa gctaaaaagt tgatgcagag aaaaaagaga
334321 gagaggttac atatacatta aaaatgagaa aggggagtcc tactctcaaa ttcaaataca
334381 aaatacgaaa atttttctaa tttcgctaga cttagatctt ttcttccaca ataccgtgct
334441 tccagatggc aacaaatgga gtggtaccat cttcacggta gttcaacatg acaaccatgg
334501 catctgggtc catggattca ccagtgaaga actcccagtc cttgaaagaa ccaataacct
334561 tcttgacgta agtttgagca cccttttcga atttaggaac ttcttctggg ttagtttctt
334621 gcaacttagc tttaacagcc ttcatgtaac ccttaatgta ggtcaagaag gacttcttgt
334681 caaaagcggt ttgttgtaga cggaaagagt ggacaacgtt gttgaccatt tcagcacctt
334741 cttcaacatc atcgtcacca ccttcagcag atgggttagc accgatatcg atgttgtcac
334801 ctccgacatt gaccatagca cagtcggctt cgtagataac gtcatcaact aacttagcgt
334861 cgtaagcatc agacaacaat tcgtcgttag agaagatatc cttgtaaata atcatatttg
334921 tctatagtat gttctgtgtt aatctgctaa ccgcaactga gaccccagaa agaaaattgt
334981 taaaaagcta aaatgaaagt agtaaaccat tgaatgaaaa cattaaccaa aataaaattt
335041 ttttttaagt cccaattgaa atacttctcc ttataaatat catgaaagga agaaaaaaaa
335101 gtgaaaaaaa aaaaaaaaac caataaaaaa ataaaaaaat atcaattcta cgagaaatgc
335161 gtgcgaaatc gatgagtttt gttttgcctc tgaaaaattc tggaaaattt ttcttagcgg
335221 aaaaaagaaa aaaaagaaac gtgatgtgaa aatgtgttca ctgagctcat cgatatacac
335281 attgaacaga cacaaatcta ttatttgttt cgattttctt ttacgtctcc aaagcagttc
335341 tactgtatag agaccagact tcttccgcta tttcagcggg tgcgcttgta ccgcttgccc
335401 caatggttct ctccagcatt tctttagcct ccactggcaa attttggatc atatcggtcc
335461 ctttgactaa acctggagat atcgtaaaac acctaatgtt tcttggttcc atttctgcag
335521 ctaaaacttc tgtaaatctg gacagtgcgg ctttagaggc ggagtaaaca gatgtacctg
335581 gaaccttcat ttttccggag tgtagaatgg aggaaatatt tacgatggtg ggtcgagcag
335641 attgaccact gagttccggc catctccttt gcgacttcat catatactta atacagatgt
335701 ttgtcatcgt cacagggctc ataaagttaa cattcattat gtcctgaatt tgagatgcag
335761 tggttcttac acttaatgat tcttgagtca agcctgcgca gttaatcaat aagtttacgt
335821 agtagcggcg ttcattattt gaccatttgt tacatgggtc gaacaatgtg gaatatttct
335881 gtttcaaggg cggtctatct ttgaaatatt cgataccgtc atatgactca tagtcaagcc
335941 agtgaggcca tttcttaaaa tcaattgcta tagcacattg ccgctgatat gataatcccg
336001 attgtaattg gcctctatct atcgcggtgc gctctatact ttctttagta gacccaagta
336061 taatgcaact taaacccttt tgaaataact tttgacatat tgccttgcct atacccctag
336121 tggcacctgt tactatcgca acaggcaaat aatgcatttc cagacttttc ttctcccacg
336181 tctataccaa tgtactcatg tgtattccat agttctcatc agttgcaaac agtaacggcg
336241 gaaattttga cgctgtgata tataaaacag aaaaagtggc atttccaaaa ccccgcaaaa
336301 taaagacaca gctagctaga tagataacac aacatatata taccttttat tatttacgta
336361 cgtatatata tatatgcaaa atttaaatga tatatgacat catcaaaagg atatggaatc
336421 cttgcccaaa cattgaagaa agtaaaacat aatagtggta ataaaatgtg tatttaaatt
336481 cattgtattt tattccccat ttcgtttttt atgtgggagg ttctacttct cccttattag
336541 tagaaacctc ttgaattttt agaattgtaa tcataaccgt tgtagccata tggtacacct
336601 tgttgggcag cagcagcggc agcggcagca gcttgttgct gttgttgttg gaattgatag
336661 tattgttgga actgcatttg ttgttgtggg ttaacaggtt ggccattttg catttgaact
336721 tcaggttggg gttgaccttg aggttgctgt tgctgttgct gttgtgattg cttctgttga
336781 gagtcttcag aatgctgggc aacaccttga tttggacttt gctgttcctg accgttttga
336841 gtttggtaat agttgtaatt gttctttggt aactggtatg gatattgacc agctacaccg
336901 tattgaggtt gaccatatgg gaatgactgt tggtaaaagt gggcgtagta tggcatgaat
336961 gagccaccgt atggctgttg ttgttgaggt tgggcgtgag ctgtagctgg agaagcggca
337021 gcagcagcgg cagcactagt caaattagca gcagcagtgt tcgcgcctgc ttgaccataa
337081 ccttgttgga aattatattg gttagcatta ccactagttt gagcgttgtt ttgagcaagt
337141 tgctgatatt gttgaccgta agcgtatcct tgtgaatcaa acatacctgg ataagaatat
337201 ccaggaaatt ggttttgata catgtagtac tgttgggcag ccacgttgtt cccttgtttt
337261 tgactttgtg gactttgctg tgattgaggt tgttgtgatt gaggttgtgg atgctgttgc
337321 tgttgctgag catattgttg ttgttgggac aaatactgtt gctgtaactg atgctgttgt
337381 tgagcgtatt gttgctgctg ttgttgagta tagtagtttt gagataattg ttcttcttgg
337441 gcttgagctt gagcttgtac tggttgttgt tgctgttgct gttgctgttg tagttgttgt
337501 tgtggttgtt gtggttgctg tggttgttgt tgttgctgtg gttgctgtgg ttgctgtggt
337561 tgctgtggtt gctgtggttg ctgtggttgt tgggattgtt gttgtggttg aggtacagta
337621 ttagcttgat cttctggagg ctctgaaata acagcactaa tttcaacctt ttcttcaaca
337681 actgtaactt cttcttctgg agcagcaaca ttatcttgtt cttgttccag ctcttccgct
337741 gtctgttcct cttcttttac ttgttccttt ttttcagctt cttcttggac ttcttctccg
337801 tccacttcag ggactctgtc ttcattttct tcagaaggtt cagcagtctc ctcctcttgt
337861 tcttgtgcag atgtttcttg ttcattaact ttttcttcac tagcttcaga cttttggtca
337921 tccttcttaa tatcgcttat ttctttcttc aattcagcaa cgttttcaag aggagactcg
337981 gtctttttaa cagcctttgg ctttggtgta gcaattgcag cccacgacat tttctttggt
338041 tgtgaagcag atgtcctaga agttgttttc tttgaagata aagaaggttg ctctatttgt
338101 ttgtgttctt ctttgttatt atgcccttcc tgctgttgtt gctcttcttg ctctttttct
338161 tgatttttct cctgcgcttg ttgcccttgt gcttctaatt cttcattatt gttatcattt
338221 gaatcttgag gaacgtcatg tttagtatct acagaaacag ctgctgccca cgatgtagtg
338281 tttgaaacag gcttggatgg tacgtgcttc cccttgtcga gattaacatg tttcccggtt
338341 gtatgagctc gtggtgtttg taccttcttc ttatttctgg cttgagtata attgttacta
338401 ctgttatgct ttgtagaagt aaaagaattg ctattattag aactcttata tgtaatatca
338461 tcttctggat ttggcaaatg ttgttgaggg acatatgagt gttgttgctc ctttttttca
338521 tatttttcct tcttagcagg tttctttact tcatcccatc ttgtcactgc gccggaagta
338581 attttatcaa ttatagtttc caaatcatca tattcttgaa ctatatcaat taaatcatca
338641 ctcgtccagt cagggaacaa ttctgtaagc gtatctattt tggactttag cgcaggattt
338701 agttttttac tactatgact attatgatta gacttcctaa attgtgtaga cattatatat
338761 atatgatgat gtagattata ttgagaaaac gaccaaacaa aaataaatat gtaagtactt
338821 tatgatggtg atttttttgg ggtaattggt aagagttttt cttgtagctt caaaagatca
338881 aatataaaat acgaatgttt ctgaaattac tgtaaaagac ttaggaaaag gaatgaaacg
338941 tttatatggg agagaacgaa aatttttcct tttcccgcca ctactttttg ccaccatttc
339001 ccgttattta tttgggcgag tgctcacctc cgacggaatc acgggtgacg gatatcctaa
339061 aaaggtaaag aattgaaaca gatctattaa tatacggatc actatacatt attataagtc
339121 gatattgcag tattagtatt tacatgttga ataatgcaca ttctgtgcta aaatatatac
339181 ttcatttgtc aacttctttt agtttgccgc cattttcaaa cggcgcctcc tccctagctt
339241 cgtctagagc aggcttaata ccttgtttga cgagagctgc gttgacacat gtagtataag
339301 cgtaccattg ttttgagcac tcgttctcaa cggattttcc cttcaggaat ttttcgctat
339361 accattcatt aaaacaacta tcgtatttcg tcttcaggtc agtgcattca ggcgcaaaac
339421 tagctgacat tatattcccc atataaaact ggtattattg ttattgtaat tcaagttaaa
339481 acacaaacag atgttttcta atgacctctc ccggcatata tctggcgcac ttagaataaa
339541 tttctacatg caaatactct gaatattctg aatgtggctc tccctatatc gaagaaaaaa
339601 tatagcgggc ccattaccct gcgttctgat attcatcact agtaaaaatt gtatgtactt
339661 atttattcta tctattcgta gaaaaatgaa tgatggtccc aggctttggt acttctttcg
339721 tactctcttc ttcatcgggc ccttcgttgt tatcatccgc ttgtcccttc gggtggtggt
339781 gcccctgctt cagaggcgag ctctctatat tattgctgtt ctcatcgtcg ttatcgccgt
339841 cgttattaat atgttcttca tgagccagtt gcttccgcat tttattgggc acaatcggag
339901 acggtaccat gctggaacta gacccgtact gctgctgcaa aagtagcgaa atctttcttt
339961 tgcggctttg tctctgtatt gtactttcat cttgctcatc atcagctcca ccatgaccct
340021 cgcctgtaag gtctgtttgc tcccttgaag gcaccgcctc tgaaccagta tcttcgtcgc
340081 tagagtccgg aagtttcaat atctgtcccg tggatgttat attcgctgtg tggaaatcat
340141 ctatactgtc gttattaaac atagaatgga catcccggtt gacatgtaca gctgaatctg
340201 cctcgttagg cccattgtct gtctgggact gcctactcgc ctcttcagcg gatgtaggaa
340261 atataccaac attattgctc acaaggcttt tgactggagc gtttcccact ggtgcagctg
340321 catttgcctg caaattcacc agcccagtct cttgaaacat agtccccagc cattcggtgc
340381 tatccatgat ccgctcacat atttctgaat atgtagccac gtgtgggatg atgtcctggg
340441 tgatcttatg aaagcagaaa ctcaagttag agtctatctt ctgcaggttc actgtaattt
340501 cttgatcaag tttttccaat gtttcctctt tgcttgcaga atccattttt tgtgtcaaca
340561 atcccttatg ttgctctttc catacgttga tcaacctggc tctattccca ccccaaactg
340621 tagatatcta ttttgttgat gcctcagctc accaaaacaa accaaaaaaa cggaaaaaaa
340681 aaacggaaaa gaacggaaac aaacggaaaa gaacggaaaa gaaaacagga aaaactcgct
340741 gttctgttac ccgcgcggca ctaccgcatt taatcggagt agctactaat caagcaaggg
340801 cctccgttcc tctatgacgc accggacata tcgcatttcc actataatag tgcaagtagg
340861 acgggataag gcccaagatt atcaatgaag actaacacaa cggtcttgcc agccatatcc
340921 aactctaaac atcttccacg gctgttcaaa aacgaagatc tcttacccct ctgcggctta
340981 agggctctgt tcaattgaag gatccgcggc agtaaagtaa atggatgaaa aaaaaaaact
341041 ggaaaaatag caactttttt cagcctggaa gatttgtcat ctaagcgaag gagaatgaaa
341101 ccggaatttt cactccttct taggggcatt cagtttataa atatagttat tccctgaagt
341161 tgagatttac tgatttaaca tctggacaac taaaaaccta aataataaga cacaattttt
341221 tgcgggattt tttttccttt agatactttt aacattcata gtaaaaagtt ctgctacata
341281 gtaaaaacac atagaaggta caagcaatag catgattcaa tttaaaagtc caggtaactg
341341 gctgttcata gtaccctgga ttgccttcat tccatggtat ggtatgctga tagccatgct
341401 tatttgctgg gccagtcaag gccatcccat atattggttc atgcactcgg agcaattccc
341461 tgtgtacatt tcagatatag gtgccactaa tttaaggcca ctgtttatat cgtgcgccgg
341521 ctggcagggt ctaggctatg taatcactgt tgcccttgag ttttttcaaa gatccggcta
341581 tctgcctttc caactgaaaa aaaaagaccc ttctatctct gattccacat cttatgctga
341641 gaaattgcac agcggtaaat acttaatgcc tccatattac acaaaggatg aacggaacct
341701 gattttcgca gcttttgttc tcggcagcat tggtgaacta gcccttttat tcagttccat
341761 cttctcaacc gccctgtacc atcgcgttca cattgctatg gtctctgttt tcgtcgtctt
341821 catgttccta tccacttgct gcttgattgc agagtatttc ctcatgggaa ggcactatgc
341881 ctcagtccac cccctagcca gccctcattt caatcctcaa tcatctgaaa aaagctttaa
341941 ccaagattat aacactgtgg atgagctgcc ttggtataaa tggaaaggcc atgtatggaa
342001 taaatttacc atcagtgcaa ctctaaaagt tatatggtta actctcgcag ttgtatgggc
342061 catttgtttt ggtgctatca atgatagatc taagagtgct tgtttcgaat ggttgctagc
342121 attttggttt ggtatcatat ttatgattct ttccgccgac ttttatttag gtggaagata
342181 cagacaatcc cgctatttca accacgtgga atcattttcg ggttattaca agtatgacaa
342241 ggcgctaggc ctctaccaca gtgaagacgt tttgccttcg gacgataacg ccggcgtgat
342301 tgccacagaa acagcatctt caaatattta caataattcc tcttccaacg aatctattca
342361 agtagtcgta tgacctcata tatgctagac ttgactagga aataccctct aacctgcaag
342421 atatattcat ctttttcttt ccaaagcaca atttaataaa acttgcaaga acatcgtcat
342481 catttccccc ttttattttt gttatccccg ttactgatgt aactaatacc taattctatg
342541 cttctcaatc tgtatagtag ttttcctttt gccgaagaat ttcttctggc tgcttttttt
342601 tttgacatat ttcgcattgt ccacaatggt cattgcgtta aaagctagaa attaaaaaga
342661 gaatattgtt cagcatatgt agtttaagtt ggcaaatttg ttctgctctt gatgtaccta
342721 gaataaataa atattaatca gaaaaataaa aaaaaaataa aagtaatgaa aaaaaatata
342781 acaaaaccaa cattaaggta tatattacag cgagtagcgg caccggttat catcaaacga
342841 ttgatagaaa gttagataac ctctttgaaa aaactttcct taggagaggt attggaatcg
342901 ttggaatcgc gaactcttat ctccgatccc tcttgatcgt cttgatcatc tgtaacttca
342961 ttactataat cattttctat cgaaccttga gaaaagccac taaaagaccg gcggccgttg
343021 tcgttacaat gggtaaaatc gtgccccttt tttgagtcca tttgatccac cacaggctcc
343081 ctcttcatag ttacagactc tgttttggat agtccttgtt tatcggcatt cttattaaat
343141 aaaaattgtt ctatcgttat ggagcctcca ctgttcgccg ctggtcttga agatttatcc
343201 ctcttgtttg cgatggaatc ttcaccggtg ccatctactg cttggtgcac tttatatgac
343261 ttcacttcat cgtcaattaa ttcattctcc ttattggagg ttggtgtttt aggcccatca
343321 tccaacacgc cgctaacacc agtgattgac ctagcactgg cagaactatc aatatccttt
343381 cctgtattat aagtagaaag gaaacggctt ttaacaacat cttttggaga tgcactcttc
343441 cctataggag tcactttttc attgttatca ggtgtactca tgataacatc tcgagaaaaa
343501 ttagaattat tctttgactc ctcagtgccc cttctagacc tcttagccgt ttccttctcc
343561 tcttcgagct tcttttcaca ctcccgcagc ataatgttcc tgattataat catttcatct
343621 acctgtaatt ctttcaacat acattcttct gtagccattt ctgcttcttc ttttgccatt
343681 tctgcagaaa taaccaaagg atcattcacg gtagcatcaa gaaggtcctt ccttgttgga
343741 attttctgtt tctgtacagc tggtatagct ccaccagcat ctgctgtttc cccaaaacca
343801 tggattgcag ttttatgttc agcaatggaa gcgacaagtc tttcgatttc tacctgtatt
343861 ttgctgcgct cctccaaaag ctcatcatac cctctttccg aatttcccaa attgtcaaag
343921 tgtgatctga cggcataata gtgttcaatg ctcgaatttt tgagatctct ttcacatgca
343981 tcgttccaat cattcaattc atcattctct cctgacaggt tcttggacaa cctttcctgt
344041 agttcgtttc ttagattttc acgattttcc ctagcatttt caagttcttt ttccttctgc
344101 tgtaatttga tattcatctt ttgtacgaac tgatcatacc gttgtccctc ctcggccttt
344161 ttagcttctt tctcctgttg ttgttttgaa gccatcgcta acaataattg cccgtcgttt
344221 tgctcttttg cacgttccat agaattccca tcctcatatt cctgatcaag aactcttgac
344281 cttctctcaa tatctttatc aacatcacgt tgtctgctgg ctcgttcatc aatttcgttc
344341 accactggtg atatcaactt tttggcgact gcgttaacct cttctggagt catccacaaa
344401 ccaccaccca aatatatttt ctttttttct tcttgtttaa cagaatagtg ctgtagagct
344461 atgttaacag caagcttatt gtaagcttgg ttaccaaata aaagcatgta agtatcgcgc
344521 gagtcaatat cctgcaattt cctattcgca agcttttgag cttcatttag cactaccgga
344581 gatgctacct gctttatgta cagtttcttt tgtgcctctc ttgcagcaaa atctgggtct
344641 tccaatgtct tcgggtcaag atctttaact gcatcagctg caccctttgc acacatatat
344701 tgttgatcac ttagcctttg tctttcatta ccagcatgag actctaagaa ctgctctgcg
344761 gaatgttcaa gtttttccaa agttcctttc ttaaaaactt ctttgttagc ttttgataca
344821 ccactttgat cgctgctttg taatccattt ttaaagttta ccttttgggg atacaacctg
344881 tcattaactc tgctaatcgc ccttctttcc gctccatcca ataccttaga taaatcgagg
344941 gatttgaaac ctgcagggtg ctgtggatta actaagtttg catcaaactc attaccaata
345001 ggggcaccag aaaacctctt ttttttaaca ctggaactgt cggaggtgcc cttcatggaa
345061 ttgtctaaag aaggactgaa agccaatgct ttttgtgcag ctaatcttgt taaaaaatca
345121 cgccttccct tcagacctaa attgaccgtt attgggacgt cttcaggcgg ggtcaatgga
345181 atcttggaaa aggttacttt gaaagcctca cctctggcct tttgctcgat tgctgtttcg
345241 acacagtcat caggcgagac tttcgttctc ttactagcta aacgggccgc aagatcaact
345301 gactcactct tggagtctcc taaaccaagt gttttgtaat tagccggagt attcaaaatg
345361 ccatacttct gtttcgcacg gaatatcgcc tctttactca atggttgtcc actctgctgg
345421 taagtagaat atatagtttt cagtttgtga acgctatttg aaattgagcg aggtgtttct
345481 ggagcagcgc gatgcatttc agaagaatgt agcgattctt gcaaagtgga tactctaacc
345541 gcctttcttt cagtaatttg ctcaggggac gtctggacag attccacatc ggtggtttgc
345601 aacgcagata ttagtgacat tatagtattg tacttgttcc taaagtttta ttgtcaatca
345661 cactctaaaa ctactgattt gaactcatgt gatcactttt gtttagacat tgtagaaaac
345721 atggtgcttt ctatgaagat tttcatgtgt taaataccat ctttgagtgc atcattttcc
345781 atcatgtata tcctgcagaa gtatccctta atcagtctga aaaagaaata acctctaccc
345841 ttaacctttg atttggagct tcatcgcgaa atatagggga ctgccaaaaa tgtcttacaa
345901 agccaacaag tgaacatgaa aaaaaaactg tcaacagcgg agagcacttg tcgaaccgaa
345961 aggtatgcta atatgacctt ataataacct tatttaaaac atttaaagta ccttaagtca
346021 atataaaccc cgaaaaaggg aaaaatcggc tccagccctg aagcacaaat atcactaaat
346081 aaactgtccc ctgattcttc ttgctagttg catgtctttc ttcattatag taattctttt
346141 tgcatgcagc gccaagaggt ttgtatgttc caataatcct accagatacg cttcgcttgc
346201 ttcctgtaac gccataatcg ccattgactg ccaacgtaaa tcctgatctt tagttgtaaa
346261 ctcgtctgta acttctttca ctagccttgc aaatggaatt ttggagatta ataaatccgt
346321 ggaacgttgg tattttcgaa tttcgtacag agctaattca ctaggagtat atttcttttc
346381 gacgcgcttt aagctctgct ttctttgttt ttccctcctt ttctgtctaa catatctgtc
346441 taaggcatat gaatgagttc gcactggtgc aggtacttca gtttccattt cagcttcttc
346501 ttcattttct gtctcgattt ctagattacc tgcttggtct tcgtagtctg tttcgatatc
346561 taggtcactt tttgagcttt cataacgtct tctttcctct cttcttggaa acaggttctt
346621 tgtcgctctt gttctctgca ataacgataa cgcacgatcg ttaatagatt gttggtctcc
346681 tgcaagcctg ttgacgttac tgagtgatct tccactcgaa tcactttgaa tagcagaact
346741 aacccattgt tgtttacttg acatgattat gttatattag tattctttct atattcagtc
346801 cttcttctgt tttttataaa gtaaattctc aagattatct actactgttt ttaagagatg
346861 ttttctcaat atttatcgat gaagttttgt ttttcttttg ttttcaattt acttccgcga
346921 tttcgcgaca cagtgggatc aagataaatc atatcgttcg atattctcgc aatagaagac
346981 cactaaactc tcaattgata aatgttgatg tcgatttcaa ttatcaatga tggtatatta
347041 tgaatattat ctttagtgtt attaatacaa atgcaaatgt gggtaatttg ccgtttctat
347101 atatatattt atgtatttac cataaccaag taaatcaatt aataatcata tttcacatcg
347161 gctatacgat tatcagctaa cccaatccga cagatatcat cctgtagttt catctatatt
347221 tgaccattat ctgcaaagtt cagatacgtt tttacatctt ctactgtttc tcgaatgtca
347281 ctatcttccg aatttatgta tgctttaaag ttgagaatat tacttgaatg agcaagcttt
347341 ctagcccctg aattgttaac cgtgcgcttt ccaacagtcc tatccattag tggggaactc
347401 ggtttgtcct gtgagcaatt aatatgggtt ctgttcccgt tctctttagg ggaactcttt
347461 agtcttatca tggctttgat aggtgttggg attttcaatg acgaatgaga ggatgactcg
347521 cttctgtcag ttttcatgtc cgaattctgc ttatcattat tcacagtcaa attaggtaag
347581 ctttcatttg acctacaaaa agtatctaag aaatccgtaa cctgaatggc ttcctcccct
347641 aacgatgaac aataatcgct cgagtctggc gaagatctaa ggaccgtagt cgaaaaacat
347701 tctttatccg gttcctcgtc gatatgtatc gaaggtgtta ctttactagt tgcagatacc
347761 aataccttgt ctttcccttt tcctgaggtc tttttctttc cttttttagt cagtagccta
347821 ccaaaaaatc ttcttacagg accttcgttt cttacggggt tcacactgga cgatgaaatt
347881 tgactgtgat tcctagaatc tatgggctgg tcacgcgaca aaacctttac taaatcctga
347941 atacttatgc gtaaagtaac gtctttctcc aataaccttt taatgactaa atcgtttaaa
348001 gtattaccat ttattttgga actcaatgat acttcgatga ttttgtggta ggtttcgaat
348061 tcattttccc cgaaaaatgg cagctcgttg tacagtaagc agtatagtgt cactcccaat
348121 gaccaaatat ccaacttaaa gccatccgtc acaaaatctc ttttggaatt gcccaaatga
348181 catagctctg gtgcaataaa tgccggagta ccaacaattt tgttcaattc cctctgaaaa
348241 caatcttcaa aattagcatc gctgaaaggt aatgattggg gagtgaaaat acaacttcca
348301 aaatcagaaa gtttcgctac tttttcttct tcatccaata aaatattgga cggtttgata
348361 tcacgatgaa tacaaccctg agaatgcaaa tattccaacc cttttgtcat atcctccagg
348421 atttttttgg caaatgtaga aacactacaa tttgaaatca caattttttt ccattgcggt
348481 aaaatatctt catcatcgtc acgtttccac tgtagttcac caaggctgca ccaattagtg
348541 actatccaga tagattcgct gaaaggagag tccaagcatt ctattagtcg cacaatatga
348601 acattatttc gaagtcttga agccgcaaaa atttcccacc tacatttttc gatattcata
348661 agtctcatag cctcattacc actcatattt gtcgttattt ttcctttact cttccaaagc
348721 tggatttgcc tcattacttg atttactgaa tattgctggg cattccaagg tttttttggt
348781 ataatcttga cagcaacaac cttgcctaaa gtagaactgt acgcttttcg tacataacca
348841 aattgtccac ttcctgcaga gactcctagc gtatattggt ttatagtttt cttatcttgg
348901 tcactaacag ttattttttt cacatatggt cgaatttcat ccaggatcgt gtgtatattt
348961 tctcctataa ttgtactata ggttggtttc tgttgagaaa aagaagaacc aaatgaagat
349021 gtctggctcg taggcgttat cgggggacta tctaactcat cctctcttat gcacgattgc
349081 tgggataatg gtgcccattc cggaattaat gtcggtataa gctgtcgagg tgacatttca
349141 tgctaagtaa ttattgttaa cctggcgttc aaaaaataat atctatgcga gtaagtttgt
349201 aacacctaaa gaagtatcat cggggggttt tcaaggccaa attagttcat aggactagag
349261 actgttgcat tgtttatttg ttgctacctc atcattcaca aattatacgt ttaaagtgat
349321 gtaaaatcat gctatatact aatttggcat aacctctgtt gagcggcatc atttaatgat
349381 ttacttctat tttaataatt acttcatttc gaacaactta atagctactt caagaaggat
349441 caagtaagtt cctcgaagca ctatgaattc cggaggtgaa gaaccaacta taaagccaaa
349501 tgtatttaat attactcaac ttttaaactc aaatggtgaa aaaccgggaa ttgcttgcat
349561 cttcttaagt aaatttgaca tgaaaaaggg aaatatcata atatggtcta aaagtattaa
349621 tggtgcggca attgacttaa gcaatattga atttaaatcg ttaccagccg gtattcacga
349681 acaaactgac gatgttgtca attttgtagt tcctaaagaa ttagatgtct gtcaaactgc
349741 caagacgaca acttatgatt acggcatcgc ctatttcaaa caaaattcgt tcgatattat
349801 tgagaatgac aatcgtattg ataggagtaa agttcaaatg ttttctcttg gtgtaattat
349861 cgatgtccaa aatgcctcat cagatagtaa aaagcacttt tataaggaaa tataccatgc
349921 gtatgctgcc aacagatact caagctatct agaaagttta ctcggtcaat ggataaggca
349981 gcgtgatctt gataagtttg atatttttga aaagtttttt gacgagaata accaagggca
350041 catggctgaa aattcagtag aagtctttga acattcaccc aaagaaagac ggcatttggt
350101 tgaatatttg ccatactgga caaggaagtt agggcctctc atatttccac tttggaaagc
350161 aagtctcctt cagtcaagga tattgatact agttcctcaa ggagaatcgt tcgaattgtg
350221 caattctttg gcctattgtg tcttcttaat atcaatgctt ccaaaaaact tgataggaaa
350281 ccatgtaagc gatgaatata ttaagcctat tttcacggta tcaacatcag atattccttt
350341 tctagagtcg ttcaaaaagg ggaacggtta tgtggctacg accagcgagg aaattttgtt
350401 gtataagcct gaaatttacg acatagtagt caaacttact tcgagctcaa ctatagaaga
350461 atcaccagaa aaagaagtgg aaattcttac cgcatctggt gaacaaaaca aagcaactcc
350521 tcttgactta gaggtgtatg aaaaacttat actgggggag ttacaagagg atgcctctac
350581 aaatgcgaca tgtcgacatc atgaggtgac agaacccata tcatggctac agtttttaat
350641 tgatgggttt tttcttttaa ctactgcagg ctatctggta gcgccatatc accttgcaaa
350701 taatttcaag attccgaggc acgtttctgg cccagaaccc aacaattcag aaatacagat
350761 cgctgaaaat ttagttcgct attttcaccg cagaacatca aatctgtaca acgatctgaa
350821 ggatgtcata caaaaaagtg aaaatattga ttcagaacaa ccgattacta tcgcagcttc
350881 atttttaacc aagttaaatt tggattgctt tagcaaacaa gatcatcaat tcgtcaagga
350941 tatcgccctt aaatggttcc aaagaagcat tgatattagc aacctaccag aatgtttggg
351001 aaatctctgt taaccactag aaacgagcta gatcatgtga gagagatagt atatgtcttt
351061 gtaactgtat tttatattta tatgtatatg gtgaatttta cttaaattcc ttggtagatt
351121 acatacacga ctctgttgct tgttcattcc ctaaaaatca gggaatctag gtaaaacaca
351181 tatgaacaaa ggtctccttt tttttttttc tttcatttct ttcatttttt tcatttttca
351241 tttatggaaa tgttaagctt tcataagttc tgcatcaaaa gactaaccac agagcacatg
351301 cgacaattga aataccaatg acagcggtaa taatacctgc acctgccttt gaacccttag
351361 tgatatttaa tggtgccaaa tttgtgggtt gcgcttgagt acctgctgcc ccatcaccaa
351421 cagatgaacc accattctct gccgtgtatg gtgcgggttt atctaaggcc ctcgtgttga
351481 ccattacttc taaggcggac atttgttcac ctagaccata cataccatcc caagtcccat
351541 tgaaccaatt caatccacag gtatgaccat cagtacctcc agaacatgat ttcgcggccg
351601 caatggcaga tgtattcaac caagacataa tttggttcct agtttctggc actagttgtg
351661 cagtgacacc taagaaacgg gcaaaatagg ctttgaagga acgttgatct gtattacaag
351721 aatttggacc ttgacaagca gcttcataca caataccatc atggaaaaac acttgggaag
351781 cgttcaaaaa ctctttggtt cttgtgtgcc agaggtctga tcccgtaaag ttgtaaaggt
351841 aggcagagcc agccaacagc aaaccttgat tatatgtcca ttgatatgag gtcactttgg
351901 tgcaattatc atcaatgctg acaccatcgt aaacatactt ataggtacca ttagaaatta
351961 agttcacacc gaccatccac tcgtaaactt tttcggccca gtcaacatat gtttgattac
352021 ctgtatatct tgctaatctt gcagctatgt gaaacaaggc accgttagaa acggtgttct
352081 tgtaatcgta accagagttc caaacgaaaa tttgccacct caaaccacca ccacaggaat
352141 cggcatccca acgcaaagcc atggtattga aaacagcctg tgctaaatat agccattgag
352201 gctcattctc gggaggatta gtaaagtttc tctccgcggc agtcatagca gcaatacccc
352261 aaaaggcttg gtcatcatta ccttcagtgg tagattgatt tagcggaata tagtcattat
352321 catcaccagc ttgatgtatc attgctgcta taatttcatc attataggtg tcgttatcca
352381 tgaaaaacca gtaatctagc atacagcccc aggcaccacc ggcttcccac caatagtacg
352441 gatctgaaaa cataccgacc gtcttaccat actgattacc agtgtaataa tccattaaac
352501 cgtaggcaat tagtgaagta gcattttgca aagattcgta gttgtctaga tccaattcga
352561 cggcatttgt aaatcttgtt gcgaagagta cacccagtaa ccctatcact ttatttacta
352621 gcatttttat gtgttcgttt ttaaaacaga ctgaaaagaa agaaagctca gaaaaaaagt
352681 ggtgtgtatt ttgttgtatc cactattata tgtcctggaa aggtttccct agcgttttga
352741 ccctttcgta tcttgtaatt taagcctctt tttaccaaaa atcctcccgt tcgcacacct
352801 attaagctgc ttataaaata tgagtatcaa cacagtaaca gtgaatatat aatagatgag
352861 cccattatac aaagagtacc tatgatcatc atgaaatccg agctttattt ccatctgcca
352921 gttttctttc tggatgtacg aaattaaatc gcgcctcgaa cgggtgcaaa accgggtgac
352981 gggacaccgc tacgaatata gtacgataca cttatacata tatggaagca tttatagcgt
353041 atattcatcg tacggtacat tctttaaata aatgattgaa tttttctgaa ccaacagtta
353101 taagctgaga tccagtgcgt tcatgaaacg gaacatctta catcatcaag agcccagaag
353161 cacggcgtag gattgtttcc gctgctacag acagacatgg aaacactgtt tttatcaggc
353221 caaaggtgat acgacaggtc tcttcttgtt tcaatattgc cttacatatc tgctgctcac
353281 tctatttgct ttttcctgct catttatagt taacttgatt tgaaattacg cgtcgcgggg
353341 aatcgcgtaa aactcgatat taaatcctgt gattttgcaa aagtaaattt tttactatct
353401 acatctctcc aatttgcaca actttgacag gactgataac tacccaggtg gagcaaccag
353461 tgacagcagg taaagcacaa taaggagaag aaatgttcag gcagtcaaaa agaagaattg
353521 cctcaaggaa gaattttagt tcatacgatg atattgtcaa aagcgaattg gacgtaggca
353581 acacaaatgc agctaaccag atcatcttaa gttcaagttc atctgaagaa gagaaaaaac
353641 tttacgctag gctgtatgag tctaaattat cattttacga tttaccacca cagggagaaa
353701 taacgttgga acaatttgag atctgggcaa tcgatcgtct caaaattctg ttagagatcg
353761 aatcttgcct ttcaagaaac aaatcgatca aagaaattga aaccattatc aagccgcagt
353821 tccaaaaact actgcctttc aacacagaga gtttagaaga cagaaaaaag gattactact
353881 ctcatttcat tttaagattg tgcttttgtc gttcaaaaga actgcgggaa aaattcgtca
353941 gggctgaaac gtttttgttc aaaattagat ttaacatgct aacctccacc gatcaaacaa
354001 aatttgttca atcattggac ttacccttac tacagtttat ctcaaatgaa gaaaaggccg
354061 aattatctca tcagttgtat caaacagttt ctgcgtctct acagttccaa ttgaatttaa
354121 acgaggaaca tcaaagaaaa cagtatttcc aacaggaaaa attcataaaa ttacctttcg
354181 aaaatgtgat agaactggta ggaaaccgtt tagtgttttt gaaggacggg tacgcatatt
354241 taccacaatt ccagcaattg aatttacttt ctaatgagtt tgctagcaaa ttgaaccagg
354301 agttaataaa aacgtaccag tacttaccaa gactgaatga ggatgaccgg ttgttaccaa
354361 ttctaaatca tctttcgtcg gggtacacta tcgcggattt caaccagcaa aaggcaaacc
354421 aattcagtga gaacgtagat gatgagatta atgcgcaaag tgtctggtct gaagagatta
354481 gctcaaacta tccgctatgt atcaaaaacc tgatggaggg tcttaaaaag aaccatcatt
354541 tgaggtatta tgggagacaa caactgagtc tgtttttgaa aggtatcggc ctgagcgctg
354601 atgaagcgtt aaaattttgg tctgaggcat ttacaagaaa tgggaacatg acaatggaga
354661 agttcaataa agaataccgt tacagcttca ggcataatta cggtcttgaa ggtaacagaa
354721 tcaactacaa accatgggac tgtcacacta tcctttccaa gcccagacct gggcgcggag
354781 attatcatgg atgccctttc cgtgattgga gtcacgagag actatctgca gaattgcgct
354841 ctatgaagtt gacccaagcg cagatcatca gtgttctgga ttcctgccag aaaggtgaat
354901 acacaattgc ttgcactaaa gtgtttgaaa tgacacacaa ctctgcatca gcggatttgg
354961 aaattggcga gcaaacgcat atcgcgcatc ctaacctata cttcgaaaga tcaaggcaac
355021 tgcaaaagaa acagcagaag ctggaaaagg aaaaactatt caataatggt aatcattagt
355081 gcagaaaggg aaaaggaaaa aagcgaagag ataactaaaa aggattaata gtatacgtaa
355141 tttagtctac tgtaagtatg gtcaaaaatt ttctttagtg agaaaaaaaa aaaaaaagag
355201 aaacgataaa cgctgtacaa taccagtgac tgcactgctc cgaaaacgtc cgagatatgt
355261 atattgtccg aattttttca tactttaata gctggccaga gaaaccttat aattttgtgg
355321 ctgcaagcta tcgcgctgtt cctctgtgac aggcaacaca gaacaactaa ccgcctgtct
355381 tttatgcctg tacacttcat taaaatttac cgttttcttc cattacaagc ggggacactt
355441 tccgtttaaa cctgcaatat gttgcagggc ctatccacgc caatttactg tggcagaagt
355501 tactgcagtg gaagaactac cttttccagc atagcctccg ccaccaaaaa atgcaggtgc
355561 tgcgttttct ggatacgtgg ctggccttta aaacgcatgg gagggacagt atctcaccga
355621 tttggtaatg ccgtgatgca acctcgagga tccggttttc aagagcggaa gtaaaaaacc
355681 gggaagatct aatatttcct tatgcaggta ttctgtgact aaaaagtata gaagactatt
355741 ttgcaccgct ccctgattag acttcgtgcg atattattga tggatatcgt ctttatcttt
355801 ccgtggacct aaaacggcac cccttcgtct aggataaacg cggtcggctc tttcgaagac
355861 taaaaaagca gccacaataa cgttacatgc aaaatcagcc cactcgaagt tagatactgc
355921 gtagacggat ttgcacgatg cgatgataaa tattagggac agtgcgtgcc cacccataag
355981 ttgctgtaga gcttacaaat tgtaaagact aattccaatc gcacgcccac ccctcacggg
356041 aataagttag aatgttgcgg aatgaacgat aacttcatat taggtaaaag ggaagaatgc
356101 aacgctgcgg tctacgggct tttttctgcg agaccaattt tcttcttttg tttttttatt
356161 tcgatattta gttttcatgc aaacgggtat tattcttgac aggccattat gtaagagtgt
356221 ggaaacataa ttcttgcaca tacgacgttt tcttaactgt tcctgtttca agttacggaa
356281 acgcctgtgg cccaggtagc gtaggcaaaa tcaagctcag aatgggttac gtaattatga
356341 cgttttcgag tgcgaggatg tcagaaagga gagccagaat tatatatata tggatgcatc
356401 tctctgcata taaaattaat ttccctttcg tacagttccc tacttttttt tccctctttc
356461 gtttgcaaaa gaaggcggcc atactcatta aaaacccctc cccatttttc cttttttttt
356521 tgtttccata taggaagaac tctacagctc gaacaataca tcaaatcaat caagcagtcg
356581 ctctcgttct attgtgtgtt tctcaccacc ttacatatct cccctcagtt cccagcctat
356641 aactttgtgg ttctcttctt ttcaacttct tcttcttgac attatacttt aataagacca
356701 ttacttcttt ttctttgctg gaattcataa ttcattaagc agaaaatatg taccatgttc
356761 ctgaaatgag gctacattac cccctggtga acactcaatc taacgccgca ataacaccca
356821 ccagaagtta cgacaatacc cttccttcgt ttaacgagct atcacaccag agtacaatca
356881 atcttccatt cgtccaacgc gaaactccaa acgcatatgc taatgttgcc caattagcta
356941 cgtcgccaac tcaggctaaa tcagggtatt attgtcgcta ttatgctgtg ccttttccca
357001 catatccaca acaaccacaa tctccatatc aacaagctgt acttccttat gccaccattc
357061 ccaacagcaa tttccaacca tcttctttcc ctgtgatggc agtgatgcct ccagaggttc
357121 aatttgatgg atcattcttg aacaccttac atcctcacac agagttgcct ccaatcattc
357181 aaaacactaa tgatactagc gtcgcacgtc caaataacct taaatcaata gcagcagcgt
357241 caccaacagt gacagcaaca acaagaacac ctggcgtcag ttcaacgtca gttctcaaac
357301 cacgcgttat aactacgatg tgggaagatg agaatactat ctgctaccaa gtagaggcga
357361 acggtatatc agtcgtgcgt agggctgaca acaacatgat taacggcacc aagttgttga
357421 atgtcacgaa gatgacaagg gggagaaggg atggaatatt aagatccgag aaggttaggg
357481 aagtcgtgaa gattggctcc atgcacctca agggtgtttg gattcctttc gaaagggctt
357541 atatcctggc tcaacgtgaa cagattctag atcatctgta cccgctcttc gtcaaagata
357601 tagaatccat tgttgatgcc agaaagccca gcaacaaggc atctttgacc cccaaatcta
357661 gccctgcccc catcaagcaa gaaccatctg ataataaaca cgaaattgct actgaaatta
357721 agccgaagag tattgatgct ttatcgaatg gagcatctac tcagggtgct ggcgaactgc
357781 cccacttaaa aatcaaccat atcgatactg aggcccaaac aagtagagca aaaaatgaat
357841 tatcataagc acataacata atccgttaac tctttgctct atgaacaaga accgaagttc
357901 tagaaaggct gataggattc gtacaatcat ttttacggtc gaacttctgt agttactcga
357961 tatataaata taaataacgg acataaaaaa aaaaattgta acattataaa tcataaaatc
358021 ataatcatat ctatttctaa cttctgacta ttgcgcaatt cgttagagtc tttccaccac
358081 gtcgattgga caaatcttta tctgtctact tctaatatac tgtacatcat acctgtcttt
358141 ttatgctgct attgtggagg aaccgtcatc ttttcgcgcg aaaaaacaat atgatgcctt
358201 tttgaaacat gttattattt gattttttaa tggcttctat tacgcgtcgt ggttggtgaa
358261 cctggtacaa aataaataaa aaaacacctg ctaaaaaata tcaaataaag taaggaaggt
358321 aatacaaaaa gagagcgttg gctcgtgtta cacaaaagcg gtttcgaaca caatcagaag
358381 aaaacaacaa ggactttttt gcagcgccaa aaaaaagaaa aaaaaaacca agagaacgaa
358441 agctttataa tagccttttt tttttttaga aaacatgaac ggatctccca ctcctaagcg
358501 atattcatcc aaatcttcaa ggctttacga cgactactat aacatcccgt atcaatattc
358561 caatccgact ccaatgaata gagactataa tgacgtgggg tcacgtatca atgcagataa
358621 actggtacca gaggaataca aacggaatac agaatttatc aacaaagctg tccaacaaaa
358681 taaagaactt aacttcaaac tgagagaaaa gcagaacgaa atattcgaac tcaagaagat
358741 tgcagaaact ctgcgctcaa agctcgaaaa atatgttgac attaccaaaa agcttgaaga
358801 ccaaaacctc aacctacaga taaaaataag cgacctagaa aagaaacttt ctgacgctaa
358861 ttctactttc aaagaaatga gattccccaa ggtcaaggac cccatggtag atgacgaccc
358921 tgtctccgaa aattatgatc agataaatgt accaaaacac agagcaccgg atgctacagg
358981 taatcctcgt acaactaaca aagtctccaa tacttcagac caagatagca gactaaaagc
359041 cattgaaaga accctctcgg tcctcacaaa ttatgttatg aggtcagaag acggtaataa
359101 cgacaggatg tcacccttac cttctccttt aaatacgata ttgccaataa ataatcgtct
359161 gaattttcaa gagccaaaga gatataatcc aaccgttaag gtaaatccgt ctgatgacga
359221 tatcatgatg tatgaaagtg cagagctgaa gcgtgtcgaa gaagaaatag aggagctaaa
359281 gagaaaaata cttgttagga aaaaacatga cttaagaaaa ttgtctttaa ataaccaact
359341 ccaagagctg caaagcatga tggacggtga tgacaatata aaacttgaca atgtttcgaa
359401 gcataatcat gctacgcatc gtcattcttc ccaatccagt cgcgattact caccctcttc
359461 ggatgcttgc ttggagtgtt ctaatgattt atacgagaaa aatagagtca agcctgaaaa
359521 taatatgtca gaaacattcg caactcccac tcccaataat cgatgatgat ttaaaaagca
359581 gttaaggagt atggcgcatt cttaaagcgt tctgtgtaat tacggcaaaa aattccatca
359641 caaaatagaa agtctttatt ttactttcca ttgttatttt ccaacagaag ccggaaacgt
359701 aaaggccttt tatattaagt gttttctcat tataggatat ataataagaa tttgtaattg
359761 ttacttttct ttcagttttc attaactact ttaaacctta gaaaatacat tccaatccta
359821 cgaatagacg tataagtaag gattaatgct atcggaaagc aacttaaata actataaatg
359881 gtggatggtt agtgtcataa tatcttaatg aatatcgctt ttgacgatat agtactagca
359941 atctgcggtt ccaatggaat ggcgtaaacg cataataatg aagttggaat aaaaatatgc
360001 tataccaaca actttcatct aagtagtctt tatttgacat atatatgtat atacaccgaa
360061 caatagattt accggtgcat ttcattatca acctttagta gtttgggggg cagttttctg
360121 ggcaatacaa agtttacttt tgatggatta tataaaaaaa gccatatggg ggccagaccc
360181 taaggagcaa cagaggagaa tcagatcggt cctgaggaaa aatggtcgaa atatagagaa
360241 atcgttgcgg gaactcacag ttttgcaaaa taaaacccag cagcttatca agaaatctgc
360301 aaagaagaac gatgttagga cagttcgact atatgcaaaa gaactgtacc aaatcaataa
360361 acaatatgat agaatgtaca cttccagagc gcagttggat tctgttcgaa tgaagataga
360421 tgaagcaatc agaatgaaca ctttgtcaaa tcaaatggct gacagtgcgg gcttaatgag
360481 ggaggtaaat tcattggtta gactacctca attgagaaat acgatgattg aattagaaaa
360541 ggaacttatg aaatctggga ttataagtga aatggtggat gataccatgg agagtgttgg
360601 ggacgtaggg gaagagatgg acgaagctgt tgatgaagaa gttaataaga tagttgaaca
360661 atacacaaac gagaaattca agaatgttga ccaagtgcca accgtagaat tagcagccaa
360721 tgaagaagag caagaaattc cggatgaaaa agttgatgag gaagcagata ggatggtaaa
360781 tgaaatgcgt gaaaggctga gagctttgca aaactagagt gttactgtga ctgtacaaag
360841 aaaataaata aataagtgaa taaataatgg tacgaataac acagtaaaaa gggcacccgt
360901 ttttagtgta tggaaaaagt tgagtgcttt accctttttc catgatgacc gttgaaacat
360961 gtacggacta tcaagtaata gtgagggtaa agacagtata tacacacttc cttttatttt
361021 cgtctcatct tgtattttca tttgaaggac ggaatattta cttttcatgg cttgtatttt
361081 tactcgattc caactttttt tcaagcttat caaattcctt taatgctatt tcttgctcag
361141 gatccatgat ctgaatcact tctttcactt catccacata gtgcttcaac atggactcaa
361201 taccgtactt caaagtcact tcactagaag agcatgaggt acatgcacct tgtaatctta
361261 aataaacggt tccagtcttt ggatcccacc cacggtaatc gatatcaccg ccgtcctcca
361321 agatggctgg tcttattctt gtatctatca gctcttcaat caattcgctg acctcttcat
361381 cttcttcggt aagttcaaat ttgggcatat ttattttgta gccaccttct ccttcttctt
361441 cttggacagc atggaattct ttggatataa catcttcacc gtaagcaagt tgcttggtta
361501 acaaatctat aatttcaggc ttgatactat tccaatggac cattctgtct ttattaatag
361561 tgagaaaatc atcacctatc attaaagact ccactcctgg acactgcaaa aaaatttgct
361621 gtgctaactt ggaatggttg atgaggtttt catcagtgtt cttaataact atactcttgg
361681 agccacgcgt ctgtagcatc tcgccatctg tggagagaaa ttttaaagca ttttcatttg
361741 gagttgttaa agtcttaata tgaattaatc tctgagaatt taagtaaaaa atcggagact
361801 tccccaattt agccactgat ttgaacattg ttagtcaatt tcttgctttt ttgcttagat
361861 tacgctgaga atgccttatg tattctaatt agtccgctaa atacgcttct ttttataatg
361921 attaataagc aatattgtaa gtagatcact gaaattcgga aaacttaaat tatttatcac
361981 ttgatacgtt agaaggctat ttctacaatc accaggactc cgctaagtgg tcctatagat
362041 ttgatgaaat gcctgctttg acggtcttga tgatacaagc taacgcttag catgttacta
362101 tactcaatgt acattgtttt atcctcaaga gaccgcagac gtttcaattt tgtgtttaaa
362161 agaacaatgg acagtatata cgtagtgcca attttcttct atggtgtatt atgcgcattg
362221 aacattgtaa tatccgtaat gttgaacata atttgggaat tgcttccgaa tcttcaacct
362281 tcatgtatac ctcttttcgg ctagagtgtg gtactttaat tactgcttag ttgttttgcc
362341 cgatttagat attgcacccg tgcacgtcac acataagctt ggtcttttaa atagtgtgtg
362401 aaaaaacgaa cttgaagaaa aagatagagc aagatatata taggagtagg aatagggaga
362461 gtggaaaaaa aaacttagcc tcaaactaat agtcaagagg atcaactatt ctgttcaggt
362521 tttgcaggtt aaaaattgaa atagaatatt ttctcggtaa tttcaagaaa cagctggtaa
362581 aaaggcagta aatttacaga aactaagagt gtaagggcac aatgagagta tatcagtttt
362641 gccgaccttt ccaattattc acctgcttct tatgctacct tctagtgttc gtaaaagcta
362701 acaaggaaaa gataagtcaa aagaattatc aagtatgcgc aggtatgtat tccaaagaag
362761 attggaaggg caaaatagac ccgtttatat cattcaatct taaaaaaata agtggattga
362821 gtgatgagtc tgatccaggc ttagtcgttg caatctatga tttccaagac tttgagcact
362881 taggtgtgca attgccggat gaagaaatgt attatatttg tgatgattat gcaattgata
362941 tcgggatttg tgaagaggag aatcgtgatg agtttattgt tcaagatgtt gtatatgatc
363001 catatacttc cacaaataga tctttggcca atccaatcat gacgttttct caaaatgagg
363061 tcggccttca tgatactaga tacccaataa aagaaaccgg attttattgt gttactgcgt
363121 tcagatcatc gacgtctacc aagttcaacg ctgtggtgaa tttcaggaat gcttatggtc
363181 agcttgcggg caccgagatc aacaaattgc cactatatgg tcttttggcg gtcgcatacg
363241 ttgtggcgat ggcgttatat tccttcgcct tctggaagca caagcatgaa ttgttaccat
363301 tacaaaagta tttgctggcc ttttttgtat ttttaaccgc agaaaccata tttgtatggg
363361 cttactatga tttgaaaaat gaaaaaggtg atactgcggg aataaaagtt tatatggtgt
363421 tcttgtcgat attgacggct ggtaaagtta cattttcatt tttcctatta ttgattatcg
363481 ctttgggcta cggtatcgtg taccctaagt tgaataaaac gttgatgagg cgttgccaaa
363541 tgtatggtgc gttaacttat gcaatttgca ttggattttt gatccaaagt tatttgaccg
363601 acatggaggc accatctcca ctaatcttga tcaccttgat tcctatggcg cttgcattaa
363661 tcatatttta ctacatgatt attagatcca tgacaaaaac agttatctat ttgaaagagc
363721 aaaggcagat cgtaaaattg aacatgtaca agaagctact atacatcatt tatgcgtcct
363781 ttttgagtgt actagctggt agtatagttt cgtcatttat ttacgttggc atgaacacta
363841 ttgatatgat tgagaagaac tggaggtcaa ggttcttcgt tactgatttc tggcctacgt
363901 tagtgtattt cattgttttc gttaccatcg cgttcttatg gagaccaaca gatacttcat
363961 acatgctagc cgcatcccaa caactaccca cagacccaga aaatgtcgcg gactttgact
364021 tgggcgattt gcaatcgttt gacgatcaag atgacgcaag tatcatcact ggtgagcgtg
364081 gcatagacga ggatgacctc aatttgaatt ttactgatga tgaagaagga cacgataatg
364141 taaataacca tagccaaggc cacgggccag tgtctccctc tccaacaaaa taacgctacc
364201 tccagcagat ttgattaggt gatgagacaa atagtttctt cgagggcagt cacgaaatgt
364261 ttacaagcga aaagaaagaa attatgaacc atatgcactt ctgttcaatg cgatgtgaat
364321 atgaatatga atataaatat gaatataaat aaataaataa ataaatgcgt tgcacgtttc
364381 ttttcattta tttgtgcgtg cttttacctg tttataactg tagtcaccaa agctatgcta
364441 tactctagac ctaacttttt cgttttgtat ttatttagcc gctcgctgga gttttttttt
364501 tttcggtgat aagatgattt atatcaaacc gaaacaagcg aaaagtttct gttcatcgac
364561 tataaaatgg aagagaaaat tggtccatag acttttcatg tgtacttgtt tatgagaaga
364621 gacgcaggaa gaccagaagt gaggaattcc ctttgttcaa ggatgaacaa cgaagccaga
364681 taacgtaagg ttgcgcgctg catcagtgct aaccttatta gctttctctg gctttttcgg
364741 tctttcctat gtaacataac atgtatattc tatttgttta tgatgagacc acgtccttag
364801 tgacaatgct ataaacccag ctcttcgatt cgtttttaat gaaagggaga agattttttt
364861 gtcaaacgct ctgagtaata gaatatacat gcgacaacat ttgtagttac ttgtcttacg
364921 cttcctaggg aacggatcat ccgagtagaa tatcatttta cgggatcact ttattcggtg
364981 tgattgctcg ttaagccgca cgaccatttt atgggcacgc ttccgcaagt tggttctttc
365041 atcagaagct ttaccacgat tggcaagtca tgtagcatgt gcgctaacat cgtttatcgt
365101 tttctgtgac gtggcttatg agcaccagag acgaataatc aacagtacat caaacaaaag
365161 ctacgtcacc tcaccaataa tccgagcttc ttgaaatggc aggtattgga ttcataaaat
365221 atgtcgctgc tttgtgcatt ttcctttagt tttttccttt tttttcatgt agctaactaa
365281 gcaagacgat tatgggaagg gaccttttaa ggaaaaacag gaaaaaaaaa tagtagcaac
365341 tagtaaaaat tcaaaaaata aaaaaagtca aaataagaac acatcagtta ggaaccgtgc
365401 ttggagtttt gagactggag tattgtccat ccaacatatt ctgctctttc accatagact
365461 tcgttggaaa tcgcctctcc cttgtactat attgtgcaga accgttcccg caattttcat
365521 tggtgcaata ataacacgct tcttcgattc tcacatttgt caagaagctg tactcttctc
365581 tcaaactcca atatatttca aattatgaac gagctgaaca ctgtttcgac taactccagt
365641 gactccacca agaacggtgg tacatccaat agtcccgacg atatggactc cgcagcagca
365701 gcaagtcacg caataaagaa aagaacaaag gcctcccggg cctgcgatca gtgtcgtaaa
365761 aagaagatta aatgtgacta caaagatgaa aagggggtct gctcaaactg ccaaaggaat
365821 ggagaccgtt gtagttttga tagggttcct ttgaaaaggg gaccctcgaa aggctatacg
365881 aggagcacca gccatccaag gactaacgaa atacaagacc acaataactc aaggtcgtat
365941 aatacgtttg ataatagtaa caataccctg aataataata cgggcaatag cggcgacaac
366001 ggtataaaca gtaacacagt tccaagtacc ccttcgagat ctaattcagt tttattgccc
366061 ccactgacac agtacattcc ccaggctggt ggcattcctc ctagtttcca aaatccagcg
366121 atacaatcaa ctatgcccgc gggtaatatt ggccaacagc agttttggaa agtgccctac
366181 catgagtttc aacaccaaag aaaaggatct atcgattctt tgcaaagtga tatatcggta
366241 agaacattaa atcccaacga gcagttgtct tataacaccg ttcaacagtc tcccataacg
366301 aataaacata ctaatgattc tggaaatgca aacggaagtg tcaccggctc aggcagtgcc
366361 tctggtagtg gtggttattg gtcctttata agaacttctg gtttactagc tcctactgat
366421 gatcataatg gggaacagac aagaagatca agttccatac cttctttgct acgaaatact
366481 tcaaattctc ttttactagg tggccagcct cagcttcccc cacctcagca acaatcgcag
366541 ccacaagcac accaacaaaa gttgcaacaa ggacagaacc tatactcgta ttctcaattt
366601 tcccagcagc aaccgtacaa cccatcgata tcatcttttg gccagttcgc tgctaatggt
366661 tttcattcta gacaaggatc agtcgccagc gaggctatgt ctcccagtgc acctgccatg
366721 tttactagca catctacaaa ccccgtaaat gttgcacagc aaacacaaag acctcaagga
366781 cagcaggtac cgcaattttc atctgagttg gatggaaata aaaggcgaca atcagccccc
366841 gtatcagtaa cattatccac ggacaggctg aatggtaatg agaataataa tggtgaaatt
366901 aacaacaata atggcagcaa taatagcggt tcttctaagg atacatctca acattcccaa
366961 gaatctgtaa ctacaccagc ggctttggaa gcatccagcc ctggatcaac gccacagaga
367021 agtacaaaaa aacgcagaaa aagttacgta tctaagaaga caaaaccaaa gagagattca
367081 tctatatcta taacatcgaa agattctgct cacccaatga ccacttcatc aactatcgcg
367141 tatggacaga tatccgatgt agatctaata gacacctact atgagttcat acatgtagga
367201 tttccgatca tacctttaaa caaaacgacc ttgaccagtg acttattgtt agttaacaca
367261 cagccaattt ccaatataca cgaagtcaat tcatatgtta ttttgtggtt tagaaattca
367321 ttggaattgt tagttcgtgt tgctctgaaa caaaagccag gtggcaagtt tttcgataat
367381 attgttggcg tggctttgtc gccaagtaat gacaacaaca aagctgggtt cactacagcc
367441 acggcaaggg atgatgctga aaaaacaaga cgtgattcac ataatgaagt acaggatact
367501 ttggaagtgc aaagcgtttt tattgccgcc ctcaatgaat gtttccaaaa aatcgtggat
367561 attcatccca aattcagaga aaacaacgac caaatttcgc cgaagatcaa agtcatttat
367621 ttatctactt ttattctttt aaattacatt ttggcatttg ttggatacga taactcattt
367681 gtacttggaa tgtcggtgac aatttttaac gaatttaaat tatacaaact tctattattt
367741 ccggagccgg atataaatga tgtgaagcct ccagttgatg aagaggtcag cactggtaat
367801 gggaatacaa aaacgtccga atttgaaatt ggatctgaaa gtgctgggca tatgaatcca
367861 tccaattcac caaattccat ggacgaaaac attagtcact attcagtgtt gtttaaaaga
367921 ttatacgttt tgctttcagt gtttgattct ttacaaagct gtgcattcgg tggtcccaag
367981 ctattaaaca tttccatcca aggttctaca gaaagatttt tttctaatga tttgggctca
368041 aaatggtgcc tggaacaaag ccaattgaga ctgaaaagcg tcttgcaaag cttgaaattg
368101 ggtgaattga tgagtgagct taccaggaat agaatatcaa tgaacggcaa taggaagcct
368161 gggttcgata ttacgaactc gtcttcactc ttatcggaat atgtggaaac tcaacctcta
368221 tccgtagcac agttattttg caagctatta attggcaaac acaatttcat caattgctta
368281 ttatcattat acgattcaga agcaggagtc tattcagatt tgacattgga tttgagttcg
368341 aaaatagcag actctctgtg ctcattgata tcaataattt tgcaagtatt gacgttgata
368401 ttaagactga atcctacgaa cagtattgat tttaattata gaccaccgaa cccacccgct
368461 aataatccga cagtgcaaga gggcccatct gctatgggct cgtctccagt cgctgggaac
368521 cttagcgctg cacctccatc ggaggggaat ccagattttt acaagaaatt actaggcctg
368581 aaacaagaca ctggcactat cctttcagac ctttgccggg ggataatttc cccctttgct
368641 attgctatcc tgcacgaggt ctacaacatc actgaactgg tcaagcagat gcctacatca
368701 ctcattagca ttatgatgac ggcaactaca acgcagaata ctcaggacac caagaagtcg
368761 caggacctgg tcatgaagct gtcaaactcg atgaatgaag tagttcaaat caccagcgtg
368821 ctgacaatga tcaagccatt caagatcttc gagcacgagc ttaataagcc cataatgtcc
368881 ctgacaggag gactttcgtc cacgaccaga aacgacgtca tgtggccaaa gtcgggccaa
368941 ggcctccgcg agtcatcagt catgaagaca ttgcttgatg aacgccgtac ttctggtaca
369001 caaccgacaa cggcgccagt agccgcagag gaacccaggc ttgagaacgt tgccctggaa
369061 aatttcgtta gtatcggctg gaagctgttg gacgattccg agttaggctg gtattgacag
369121 gtaactatgc tcccttctcc tgtaggtcag gttctccctt ctcctcaggc agaaattcgc
369181 gtaaagaact accatgcaat gaatgaccaa tttaagtaaa acacataaat aatacttact
369241 tacacatata cacactagct gttttaacct gtaacaatac tgccttgtca gagtgcgcac
369301 ggccttttac tctggtgctc caccatcttc cacggtattc gagagtcgcc aagctcaggg
369361 gcgcatgcag acaatgggcg gggagcacct tcttctttca cagctaaagg ggtctttctt
369421 tctcctactt ttggcatact ttttcagggg cagaagtcct tattacgcac gttgctaccg
369481 ccggcttgct gttacacctg gtgccatcac tattgccatt gccattgcta cagattcaat
369541 tccggcgctt gcaaagtcca aagttctggt gtcggtttgt tctcacacag atccctgtac
369601 agcgtcttgt aacctgatcc ccttcccccg ccccttctcg aacagcctga cgcgcttcct
369661 cttttgtttg ggctcggccc gtttttgcat ttcctttccc tgttttggat tgagtatata
369721 aatctaaaca aacaacaaag ttcttccagc aggtaccatg agattgaagt tacggtttta
369781 ggagttggag attcaatttc tggttctttc cacatcagca acgttaaaag gcctagtcct
369841 cttccgatta tataatataa cttccacagc aagtgtacca taacataata atgtccacta
369901 agaagcacac caaaacacat tccacttatg cattcgagag caacacaaac agcgttgctg
369961 cctcacaaat gagaaacgcc ttaaacaagt tggcggactc tagtaaactt gacgatgctg
370021 ctcgcgctaa gtttgagaac gaactggatt cgtttttcac gcttttcagg agatatttgg
370081 tagagaagtc ttctagaacc accttggaat gggacaagat caagtctccc aacccggatg
370141 aagtggttaa gtatgaaatt atttctcagc agcccgagaa tgtctcaaac ctttccaaat
370201 tggctgtttt gaagttgaac ggtgggctgg gtacctccat gggctgcgtt ggccctaaat
370261 ctgttattga agtgagagag ggaaacacct ttttggattt gtctgttcgt caaattgaat
370321 acttgaacag acagtacgat agcgacgtgc cattgttatt gatgaattct ttcaacactg
370381 acaaggatac ggaacacttg attaagaagt attccgctaa cagaatcaga atcagatctt
370441 tcaatcaatc caggttccca agagtctaca aggattcttt attgcctgtc cccaccgaat
370501 acgattctcc actggatgct tggtatccac caggtcacgg tgatttgttt gaatctttac
370561 acgtatctgg tgaactggat gccttaattg cccaaggaag agaaatatta tttgtttcta
370621 acggtgacaa cttgggtgct accgtcgact taaaaatttt aaaccacatg atcgagactg
370681 gtgccgaata tataatggaa ttgactgata agaccagagc cgatgttaaa ggtggtactt
370741 tgatttctta cgatggtcaa gtccgtttat tggaagtcgc ccaagttcca aaagaacaca
370801 ttgacgaatt caaaaatatc agaaagttta ccaacttcaa cacgaataac ttatggatca
370861 atctgaaagc agtaaagagg ttgatcgaat cgagcaattt ggagatggaa atcattccaa
370921 accaaaaaac tataacaaga gacggtcatg aaattaatgt cttacaatta gaaaccgctt
370981 gtggtgctgc tatcaggcat tttgatggtg ctcacggtgt tgtcgttcca agatcaagat
371041 tcttgcctgt caagacctgt tccgatttgt tgctggttaa atcagatcta ttccgtctgg
371101 aacacggttc tttgaagtta gacccatccc gttttggtcc aaacccatta atcaagttgg
371161 gctcgcattt caaaaaggtt tctggtttta acgcaagaat ccctcacatc ccaaaaatcg
371221 tcgagctaga tcatttgacc atcactggta acgtcttttt aggtaaagat gtcactttga
371281 ggggtactgt catcatcgtt tgctccgacg gtcataaaat cgatattcca aacggctcca
371341 tattggaaaa tgttgtcgtt actggtaatt tgcaaatctt ggaacattga aggtgcggct
371401 tgcaatccct tttttacttt caattctccg ttaggttatt tattctacta cacgcagttt
371461 ttttttttca atgggttata tatctctaat atatacacat ttatatgttt agacttatac
371521 agaagcaaaa aaaaatgcaa aagaagctta gtgttcataa ttcttcactc acgtcatgtt
371581 atatatttgt taagcgtagc ttcagtatat atagagattt tcctttggcg gggtaagggt
371641 ctgtgaactt tagggaaata gaataaacgt aagttaaagg tgacaagctc ggatcgtcat
371701 ctttcaatta tcaccccaaa agatattgta aaaaagcaag ttcaatctcg tttgttacat
371761 ttgtcccgta tttctactaa ttcaggcaaa aaaggaaagt cctacagcaa aagaggcaaa
371821 agtacagtat ggaaatcgat ggcaacactc tggtgttcat aatagtgatc cttttcctat
371881 ttttctcctc accgggtggt gatggtgtgt cttctcaata tgagttcaat caactccaga
371941 gactcaagca gcagttccga acagagcaca atacgttcgt caatatgaca tatacagata
372001 gttttcgaaa tattaccggg cttaaactca gctaccaaga catgctgaat aatcctctcc
372061 aaaatgccac ttacccacta ccaggaaaag attatgatcg atggtttccc aatcaaaact
372121 acatggtttt gcccaacgat gtcatagagg ccataaatac tgaagtctgg aatacttcga
372181 atgatgacgc ttccaacctt ttccctccca atattacaag caccctgtta ggtaaaatcg
372241 accttgtatc aaataacaag tacgaaaaga taaggatgcc tgtacccaga ttctatgagc
372301 cggcaactga tttttcagag gatattcctc ctgaaggtga gacgtactgg tctgagtggc
372361 cttcgtatgg cgaacttcat aatgtgagtt ttcagcatgg cgaaatagct attcaaattt
372421 ctcatatgag caatcttcag gacaataata attacttaag gagaaatttc ataaataaga
372481 aaaatgaccg ttggaagttg ttaaatcttc agattgattt ctcagataag gctgaaaagg
372541 aaaagcattc catatactcg aaggctgtat atgacattca acgtggtaga attctttcta
372601 tttctcagag ttctaaattt cattcattgt tcgcccttcc tcattacatg tccttccaga
372661 atgattataa tgagaaaata tttaatgatg tcaaggaact cgttgatgaa ttttggaatt
372721 tcacggatta cacagatgtc atgaccatga aagacgtaca ggatgcttat aataatgcca
372781 actttaaatg tgagtatttg atttttcttc agttggaacc atggaatcag tacacaagag
372841 atcagatcaa gttaatagat gatgaattga attggcccct ggggcgtccg gcaaatctgt
372901 ctagtttacc gcccataaat gttgtctctg gattactgta ttctccagac tgtggcgtac
372961 gattagggct tcataacgta aagggtacac ggtacgaatt aaaaataatg tcgatcagaa
373021 aacatctatt gttcggtatt gcattatttg cagcccagat atacttattg cttactcaga
373081 tgcatcatac aaataccccc tccatggtca acaaaatctc attctattgt ttctcaatga
373141 taaacttagt cgatggttcc ttggccactt tgtactttgt cgcagctagt gtcgttcccg
373201 aattgtactt acccctagtt ataagtgctt tttcgtgctt tatcttggca tctatttttg
373261 aaatacgcta cttaatttca atttacgctt cacaggttaa cgaacagaat gttgggatta
373321 tcaacctcct gcgtggtaac actggcacat atgatgagaa taggccaaga cccgcattca
373381 ttcccgatga agggtctatc ggtggctcgt tatatggtag gtttttcttt atgctaatca
373441 ttttcacgtt tttaatattg agttcaactt catggccccg tcagctaagg atggtatttg
373501 agtatatcct aatcttcata ttaaactcat attggatccc tcaaattttc cgtaacgccg
373561 ttaaaggtat tccttcaaga agagaaagag caagatctag cattggagga aatagaagtc
373621 aaaacaaaat gccattattg tggagttttg taattggtac aacaataatt agaagcttgc
373681 ccgttgtgta tgttttcact tactcctcta atgtgttcag gcaccataaa gatgttcatt
373741 tcgtcgtatt tttatcattg tggctactgt ttcaaattag tatactgtat tctcaagatg
373801 tattgggatc gcgctggttc ttgcctaagc acacaatacc tgatggatat tcgtatttca
373861 agcccctttc aaacgagtat atatcggagc atggtggtgg aactgctgaa cataccgttg
373921 attgcgcgat atgtatgtct gatgttccaa tttacataga ggaaattcca gaaactcata
373981 aggtggatca gcactcttac atggtaacgc cttgtaatca cgtatttcat acttcgtgtc
374041 tagaaaactg gatgaattat aagttacaat gtcctgtgtg taggtcacca ttacctccgt
374101 tgtagatagc atctcttgat cctaagaact atatactgta tttgtattca agatccaaga
374161 taccgtgaca tttcctattt gtcaaccatt gcaataagaa attttacatg aatagtgcat
374221 taacttttta ttaccactaa agtagttttg cttaaatata caataggcaa actagactta
374281 ggataattca caagggtttt tagtgttacc ctttttccgt atgacacatt tttcgaggaa
374341 ttaattattg ggaaaatatt gccgatcaag atccattgag gtgaatctaa atcgctccaa
374401 ctccaagttg gggaatctta agaccgtcac tgccttccaa ttacactgct tttgtttctt
374461 tgacaataag aacgcaaaag taaatttctt ttttttaaca aattatgaca catcctgtag
374521 cagtgaaggc atgtctattt gacatggatg gtcttctcat caacacagag gatatttata
374581 ctgaaacttt aaatgaaact ctcgcagaat ttggtaaggg acctttaact tgggatgtga
374641 agattaaatt gcaagggctt ccgggaccgg aagcaggaaa aagggtgatc gaacactaca
374701 aattaccaat aactttagat gagtacgacg aaagaaatgt tgcattgcaa tctcttaaat
374761 ggggtacttg cgaatttctt cccggtgcat tgaatttgtt gaaatactta aagttaaaga
374821 acattcctat tgcattatgt acgtcttcga acaagactaa atttcgcggc aaaacaagtc
374881 atttagagga aggttttgat cttttcgata ccattgtcac tggtgatgat ccaagaattg
374941 caaaaggtag gggtaagcct ttcccggaca tttggcagtt gggtttaaag gaattgaatg
375001 agaagtttca taccgatatt aagcccgatg agtgtatagt gttcgaagat ggtattccag
375061 gcgtaaaatc agccaaggca tttggtgcac acgttatttg ggtcccccat ccagaagcac
375121 atgctgtttt gggggacaca gaagctttgt tagccggtaa aggtgaacta ttgtcttctt
375181 tggaaaaact ggaaatgtcc aaatatggac tgtgaatttc cagtatttac gtaaacaata
375241 tatttgtata ttgcactaag tataaaaagg gatgatttgt atttgattta tcacactact
375301 ttatgtggtg agctcagtta tttttgtata atatactata gtacatgttt gggtttttat
375361 cgttttattt caatctcatt acaataaaat attatagtga acatgcacat cgaaaggaaa
375421 gattgcaata gctggtgttc aaaagctttg tgcaaatgaa ttcagacacg aatgcattta
375481 aggacataag aatttcatgt gttgaacttt ctaggatcgc ttttttaccc accgaatcat
375541 ttgatccaaa ttcattaacg ctattggcat gtttaaaaaa agttgaagag aagttatcag
375601 catacgaaga cgattcactt tcgccaaaat ttgcagatta tgtttttgtt cctatcgcga
375661 gtttattgaa acagccagct ctcggcgagt ctcaaacaga atacgtccta ctaattatat
375721 ttcatctctt acggacatgt tggtcatcta atggtaaatt ctccgagcaa ttgggacaac
375781 aactgttccc cttaatcaca tttttagtca gttctgataa agataatcaa aaattaatta
375841 ctagatcaga cgagttcaag tacgctggtt gtttagtctt gcatcagttt ttcaaatcag
375901 taagatcgca aaggtaccat aaagagttct tttcgaactc aaaacctaat ttacttcccg
375961 ctctaggaca ttctgttacc attctgttga aaattctgga gcaatcgccc caaaataatg
376021 agcttcaatt caaagctttg gcatccttag aagtactatt tcaggacata atatctgatg
376081 gtgaaatgct ttcctttatt cttccgggga acgtttctgt tttcgctaag atacttacta
376141 aaccaggccg tcaaatacat tataaggtgt gtgttcgcac gctagaggtt ctggcaaaat
376201 tattggtttt ggtttacgat gattttagtt tggatatcaa agtaaataag ttaacagata
376261 ttcgagagtt gagcgataca aagttaaaac acgagataaa tcaatcattt atgtttaatg
376321 gacctattgt tttgttacgc acagatggga agacgcatag agatacaagt tggttgacgg
376381 caacttctgg gcaaatcaat attgctttgg aggcctttat acccaaacta ttaaaacgta
376441 ataatgaatc aattgatgag gcattagcga catttgtatc aatcctttta actagatgtg
376501 aaaattcttt aaataattgt gagaaagtgt tggtatccac tttagtacat ttggagcgtg
376561 atccgatgtc caaattacca tcgcatttgg taaaattaaa ggaagttgtc aatgaagacc
376621 tgcacaagct aagtgacatt attcggtttg aaaatgcaga taggttatca tctttatcat
376681 ttgcaatcac tattctagag aaaaataacg aaagagatac aatgatcaat gaggtagtta
376741 gatgtttatt tgaatcgctt aatgaatcta ttgagccacc aagtttgatc aatcataaag
376801 agagaataat tgaacaaagt agtcaattaa caactacagt aaatttcgaa aacttggaaa
376861 gtacgaatgc tctgattgct ttaccaagat tatcagaaga catgtcactc aaactgaaaa
376921 aatttacata ccatatgggt tctttgttgt tagaaagaca tattctcaac gatgtggtga
376981 cagagttgat ttcagaacaa gttgattcac caagaacgca gaagatagtt gcgctgtggt
377041 taagcaccaa ttttataaag gctatggaaa agcaaccgaa ggaggaagaa gtctatctac
377101 aatttgaatc tgatgccaac tattcctctt ccatggttga agaagtgtgt ttgattgtat
377161 tggaattttg caatgaactt tctcaagaca ttagcatgga gattgaaggt aaaggcataa
377221 aaaaaagtga tgagtttgcc gtatgtacag ttttattctc tattgaaacg atttgtgcgg
377281 taatgagaga agaatttcaa ccagaattga ttgactatat atacacagta gttgacgcct
377341 tggcatcacc gtccgaagcc attaggtatg tgagccaatc ctgtgcattg aggatagcag
377401 ataccctata tcatgggtct atcccaaaca tgatcttaag caacgtagat tatcttgtag
377461 aatctatttc ctcaagattg aattctggga tgactgaacg agtgagccaa atattaatgg
377521 tgatttgcca attggctggc tatgaaacca ttgaaaattt taaagatgtt attgaaacga
377581 tatttaaact actggattat tatcatggat atagtgatct ctgtcttcaa tttttccaac
377641 tatttaaaat catcattttg gagatgaaga aaaaatatat caatgatgat gagatgattt
377701 tgaaaatagc taatcaacac atttcacaaa gtactttttc gccctggggt atgaccgatt
377761 ttcagcaagt actcaatata ctagataaag agacacaggt taaagatgac ataacagacg
377821 agaacgacgt cgattttttg aaggatgata atgagcccag taattttcaa gaatatttcg
377881 actccaaatt aagagagcca gatagcgacg acgatgaaga agaaagagaa gaagaggtgg
377941 aaggaagttc taaagagtat actgaccagt ggacctcacc tataccatca gattcataca
378001 aaatactatt gcaaattttg ggttatgggg aaagattatt aacccatcca tcaaaacgat
378061 taagagtgca aattcttatt gttatgaggc ttatatttcc cttgctatca acacagcata
378121 atctgttgat aagggaggtt gctagtacat gggactccat catacagtgc gtcctatgct
378181 ctgattattc gatcgttcag cccgcatgtt catgcgtgga gcagatgata aaatattctg
378241 gtgattttgt cgccaagaga ttcattgaac tttggcagaa actgtgtcag gattctttta
378301 tattgaaaga actgaggatt gatccaacgg tgcacaacca tgagaaaaaa tcgattagta
378361 agcatgtcaa attcccacca gtaactgaaa atgcgctagt atcgatggta catatggtgc
378421 tagaaggggt caaaattaca gagtatttaa tttctgaagc ggtacttgaa caaataatat
378481 attgttgtat tcaggttgtt ccagtggaga aaatatcatc tatgtcattg atagtggggg
378541 atatcgtgtg gaaaataaga aatataaatt aaacttatgt ggctaaacat atgcatttgt
378601 atatggtaat acagtggttt attattgctc acattgttca caccagtgac tatagtgatt
378661 acaataagta attagacaat aaatgttatg agtgatccag aatgaggaat gatatgtgac
378721 ttcagaatta gcagggcagc taaattaaag atcttttaat tcaattttag cttacgattt
378781 atatctatga aagacatgaa ttgtcacttt gggtaaccaa tgatatcggt gactgctatt
378841 tatacctatc tcatattata ttaagaagac cagcttttat tctcggttgg tagtaccact
378901 tgtctactaa tcatcaacaa tatattctaa taaagtatta tgtacatata tatatatata
378961 ttaccagctc ggccaggcat tggaaaacag aagaaacatt tctcatgatt gaaatggata
379021 aacacgttaa tcaacaggga ctatgttgca ggtgaaatat tagcaattaa taagaagggc
379081 aatacgcata ttacaaatga agcgatagaa cagacagtgt ccaagtaatg ataataacca
379141 atatatgcga gtattagtat tttcctaaaa aaaagcaaga ttatatacac ggaatggagg
379201 agcagtagct actttagatt cggagttccc ttacacttgg agaagtaagt ctgctatcct
379261 gaaaatatcc gttatactaa gggctccagt aatagcgggc atcttgacaa tcctaatatc
379321 cttagggtgg tgactagcac tcacctttgt tggagtgaaa tcgtaatatc atctattgac
379381 tagtatttat gttattagta cacattatcc catgcggcgt caaaagatga catgaaaact
379441 gagaaacagt cataagactc aatggaagcg cagaatctcg gaactaaact agttgtccag
379501 gtatttacac gtttaactgg tttgtctagg cagggtatcg tttgatgtaa taaattttgt
379561 ctgctttgta acgagtgttt ctgacatgtt tcaaacatat tttatgtgta agttgataag
379621 tcgcccttgt gtatcgtaca actatgccac tttaaaatga tcaattttac agattaatag
379681 gtttcgtggt ctagtcggtt atggcatctg cttaacacgc agaacgtccc cagttcgatc
379741 ctgggcgaaa tcaattaatt tttttggctt catcacgctc gtcagttgag ctcgcacagc
379801 atcagaggca aacttgaatt tggcttaagt atattacaaa aacaagaagg agggaagact
379861 acacacatgc gtatatgtat acaggcaaat acatatagac tgaagttaga aaaagggaaa
379921 gaaaaattat tattaaataa agtaaaattt gtagtaatag gaaatagagt agtacaatat
379981 aaaacaaatg ttgaaaaagg aattccttat tctcgttgtt tgcgtgggat aatgttacag
380041 tggaaaacta aagttgttta tttgttattc attttttatg atcgaaccat ttgtagtggg
380101 gtcagccaat aacatgtgtt gttgttgttg ctgctgttgt tgttgttgtt ggagcggctg
380161 ctgctgtaat gaaatcggag gagaaacggg cgtatttggg ttggtactgt tactgttgct
380221 tccggtaact gagtcgatgg catttgcggt tatgtgctcg atactgtctt ggttctccat
380281 gattttagtg tccatattca aattcatgtt catggcctta tgtgagtgac cggttgggtt
380341 accgtttgga tcattttcgt cgggataaca actttcccat tcctttaatc ttttcttgta
380401 agtttcagtg tattccgcct ttttggcagg gtctaactcg cgccatcttt caccgattat
380461 cttggtaatt tcgattaaac ctttatcagg attttccttg acgacggtag gtctaatctc
380521 ctgggtgaac tgaataaagg gaccagaggg tctctttggg ggcaaagtct tttcgtaagc
380581 atctctcaca actctgtact tctcccagtt ggttctgaat tcttcgtaga atggtttttt
380641 ttgatcatcc gttaactctt tccaccttgc agaagccaat ttagacaatt cggggacctt
380701 tgcttcaggg aattgttgaa gcaactcatt tcttatggac atagaaaaca ggaaataagc
380761 ggaagaaggt ctctttgggc cttgcttttt cagttgtttt cttctctcaa ttctgctttg
380821 agtggaagat aatttcttca ccactggatg ctgttgttgc tgctgttgct gttgtagatg
380881 atgatgttgt tgttgaagtt gttgttgttg ttgcaactgg tgttgctgtt gtagctgctg
380941 ctgttgctgc aactgctgtt gttgttgtaa ttgcagctgt tgctgcatct gctgctggtg
381001 gtgagtcaat tgaggttgca gattgggtgg taacaaacca ggatgagtag cggtgttggc
381061 atttcctgca gcatttcctg cagaggaagg gtccaaaaga ctagacagag cgttcatgtt
381121 gttcgggtag tatctctgca cctgtgggag ctgagacaag tacgaagccg ggccagcagc
381181 attgtttgcg gcggccgcag cagccgtggc agggtttaat tgggaggctg ccagctgggc
381241 aggattactg ctagtgctgt tattgccgct actaacattg ttgttgttac tgttgttgtt
381301 actagacgcg cctgtacccg tgacagaagg gtttgtctgt ttttgagtta aatgacttaa
381361 aaaggagttg taaaactcgg aaaattgttg ttgattgatc gtcggatagt tttggcccga
381421 tccggtttgt tgcatgtaac cgaaatcctg aggtagcgcg ttaacattaa cattgttgtt
381481 tgaatttgag ttcgaattag catactgttg ttgttgttgt tgctgttgtt gttgttgcga
381541 ctgcgaagta ggttgcgtca aagattgtgg aggtagtgga taataaacat tttgctgttg
381601 ttgttgaggc gactgctgga agtgaccttg ataaggcgct tgttgttgtt gctgttgttg
381661 ctgctgctgc tgctgttgtt gttgttgagg ctgggcttga aactggttca agtattggtg
381721 aggtgtctgg tgagaagcat ctctgtactg ggagtcgttg tgttcgagac cctgatactg
381781 cagcgaatgg tcttggccta tgttgagtaa gttggagtta gaggcgtcgt cctgtttggg
381841 cgagataccg gtgttcattg cagttgtggg tactgttagc gtcgtacgta tatcacagaa
381901 tggatagaag aaggggatat agttgtggtc ttgccttgac ttgcgttgcc ttgccttgtc
381961 tgtgtgtaat agagttcttt gtgggatatc agagcgaata aacttcagcg tcacagtctc
382021 ggtagcagta gctgttaggc agtgacctag cagtagagga aacagaatac aatgcagtac
382081 gattacggta cagaggataa cgaagtaaac cacatttaca gcgagaacga gagacagaag
382141 gagagagaga acgaatgcgc cgggccgtgt ctatacttgg ctccaccagc tgatgtgtgc
382201 attttttttt tgttcccatt cgttctctca ccaaggggag gtggaaaaga aaagaagaaa
382261 aagaaagtaa ggaaggtccg ctgcgcctct cctttgctgc tgttgcatcc ggacatcaca
382321 cccaacacaa aaccccgcgc ggccgtcgtc agtaaccgtt ccacccattc ctccacggta
382381 tgtagatcgc taagcacgat gtgtatgttt tatggatatg tgccgatttt ttccgcattt
382441 ggtatcatat tttgttttga taattaccgt tcttgttatt gctagttgct tgggttaatg
382501 ttcttgtgct attgttgctg ttgttattgt ttttattatt gtattattgt attattatta
382561 tattattatt attattatta ttattattat tattacggta tgtcaagtat tatttttttt
382621 ttaaaaataa agaaaaaaat tgtacaaata tatatattta tatattactc tatatggttt
382681 ttttttttta agtgcaggcg ttggttatgc ttcgtctaca attggttggt gtgcaccgat
382741 gggtcatgtt ggaccttgat cataggtctg tacacaggct cccacatttg ggctttgacc
382801 cactgtaaac attcgtcaaa gtcacgagga accttgacag tttcgccggg agctcctccc
382861 ggtacttgtt cttgctcgat acgggcggtt ccctcctcga gtgcttgcaa gatcacagcg
382921 gtagctagac gcgcagaagt gttggtgatg gtgtccaggc cgggtagcaa cccaggtctc
382981 gagtcgccct ctcttagtgg cgacaattcg gctagttggt ccactgcagc ggagatcatc
383041 ttgtctgtga tggtggtggc acgcgatagt acggcaccta aaccgatacc tgggaaagag
383101 taacaattgt tgttctccga gatacggtaa ccatcaacag gtgggaaagg agatccggta
383161 gctacaagag cgttgttgtt ggtccacttc attaaatcgg caggaacggc ttcgtgtagt
383221 ctagtagggt tggataatgg gaaaatgatc ggtctaggat tgtgcttgtg catttcttct
383281 acgacatctt gagtgaatgc gcctgcttgt gtggagcagc caaccaaaca cgttggtttg
383341 acgttctcca ccacatcatg taaagagcgg gtgttgatac cagcccattc cgcatcactc
383401 ttagcgtata cgtgttgggc gggagtggag ttagcctcgt aagattgtag aattaaccca
383461 cgtctgtcca tcaagaagat tttcttgcgc gcttcttcct tgtcaacgcc gtgcgtgacc
383521 atatgattca caatttgatc tgcgataccg aggcccgcag acccggcacc gtaaataagc
383581 actctggtgt ctttcaagtc tctgttggta tgtttcaaag cagcaatcaa cgaggccatc
383641 acgacggcac cggtgccctg aatgtcatcg ttgaatgatg gcaattcgta cctgtacttt
383701 tctagtaatc ttctagcgtt cttaacaccg aaatcttcga aatgcagaac ggcgcttgga
383761 tacactttct taacggcctt gatgaatttt tccaagaagt cgtcatattg cttacccctg
383821 attctggaga acttgttacc catgtacaat tcgtcacggg ctagtttctt gttgttagta
383881 ccgacgtcca aacacacagg tagcacacgg ccgggatgaa taccaccgca cagcgtcatc
383941 aatgccaatt tggagatagc aatacgtaca ccaccgatac cttggtcacc aattcccaga
384001 ataccttccg aatccgacac aacgatgtag tctacatctt tgtctccacc gtatgtagcc
384061 aatctacatt cgatggaatc aggttcggta atgtctaaaa acacaccttc tggctttctg
384121 aacctgtggg aataggcagc aatagcatca ccttcggttg gggtgtaaat gataggaact
384181 aattccttga tatgtctcct tattaatgca aaatatagga ctttgttctg tactctcaaa
384241 gacgtcatga agtcgttttt ggccaagggc gtcttcaaat agcataactg cttgtagctt
384301 ctttccagtt gttcgtccaa agtgttcact tgtggtggta gcaatgcttc taaattaaac
384361 gcttcccttt cttcttgtgt aaatgcagaa cccttgttaa ataaaggaga gtttaaaagt
384421 tgaaagctct ccaagggaca ttctatggca ccttctacag tcaaacgagt ggcatgtggg
384481 tgaggagctt cgaagatctt tctggcgcga gaaccgacgg gtgttttagt gacctcctcg
384541 tcgctgtatg gcttttggaa agtattttct cttgttgtgg tagctttatg cgatctagtg
384601 ttagaagaat ataaacgcga ttgctgaata ggccatcttc ttaatggtgc tgtccttgat
384661 gctgtcaagg atctggttag ttgcgatcta gcagcaacgg aaacggatag tctggttcta
384721 agcataaccg tatttctacc ttttgtcttg gtatttatgt gcactaaact cgttaaaagt
384781 tgtaggtttc aaaagcacaa atatccgaag ctggacacaa tatacgagta agtataaaga
384841 tacgcatata tatatatata taatatgtca atcatgccgg taacgggtac gacttcgaaa
384901 ctctatagcg ctaaagctgt agaccaaagg aagtcaaatg gagcatacgc ggtacagtaa
384961 taggaaattg cgaaaatttt tcaccataga aaggcgatga tgagtcgaag ccaaggggac
385021 tcagtcactc agtcagctga tgcgatgcga tgttagcgca aacaataacg cgtacgataa
385081 taaaacttca aatgcgccaa ttcttttttt tttttttttt tttttttgat ttcttttcat
385141 atatccgatt taaaccgcct agggaagagt aaaaacccga attgttccgt ctatacttgg
385201 ttgtatgggt gttttttctt cgatgctttt cgtataagaa gatatgcagt gaatatcttt
385261 caatcgcctt gaacggttga caagacgcaa gaatttgaaa aaccttgcaa tgcacgatgc
385321 aatattcaat ttgcacacat cgaaacgaat tggtatcgaa aataaacgcg aaacatatga
385381 gaaatttttc taacttttct tccttcgtta agagtgatcc ttgcactgtg atgaatcgct
385441 ataattgttg taatgattga cactgggtga agggcaaagg atgtccaaat gataaaaaaa
385501 caaaaaaatt tggaagtgta aattgtacca tgggcgaatt tcaggttact attgtagtct
385561 ggtgagttaa tacgtaataa tacttggttt ttttttttgg ttttttacta agcgttaccg
385621 tgtgtagtga ttatctaagc ggttcttgca agattaggaa aaaagctaat taagtgtaaa
385681 cttggcagca tgattgctcg tcctaatcga gccaaagata gaaaactact ggaagcagct
385741 gctgcagtga gtagagtatg gatagaccta tagatgatat tgtgaaaaat cttttaaagt
385801 tcgtcgttag ggggttttat ggtggctcct ttgtactggt actcgatgct atactatttc
385861 actcggtcct agctgaagat gacttgaaac aattgttgag cataaataag acggaactgg
385921 ggccgctaat tgctagacta agatcagaca ggttaatatc catacacaaa caaagagaat
385981 accctccaaa ctcaaaaagt gtggaaagag tttactacta tgtaaaatat cctcatgcta
386041 ttgacgcaat caaatggaag gtccatcaag tcgtacaaag attgaaggat gacttggaca
386101 aaaattcaga acctaatggt tacatgtgtc cgatttgttt gaccaagtac acacaattgg
386161 aagctgtaca attattgaat tttgatagga cagaattttt atgttcccta tgtgatgaac
386221 cgttggtgga agatgattct ggtaaaaaaa acaaagagaa gcaagataaa ttaaataggt
386281 taatggacca aattcagcca atcattgatt ctttgaaaaa gattgatgat tcaagaattg
386341 aggagaatac tttcgaaatt gcattggctc gcttgatacc acctcaaaat caatcacatg
386401 cagcatacac gtacaatcca aagaaaggca gcaccatgtt cagaccggga gattctgctc
386461 cattgccaaa tcttatgggt actgctcttg gtaacgacag tagtagacgt gccggtgcta
386521 actctcaagc cacattacac atcaacatta ccacggcaag tgatgaagtg gctcaaaggg
386581 aattgcaaga gagacaggct gaagagaaaa gaaaacaaaa cgctgtccct gaatggcata
386641 aacagagtac catcggtaaa actgctcttg gtagactgga taatgaagag gagttcgatc
386701 ctgtagttac tgcatctgcc atggattcta taaatcctga taatgaacct gcacaggaaa
386761 catcctatca aaataacaga actctgaccg agcaagaaat ggaagaaaga gagaatgaaa
386821 agacgttgaa tgattactac gctgctttgg ctaaaaagca agcaaagctc aataaagaag
386881 aagaggagga ggaagaagaa gaagaggatg aggaagaaga agaggaagaa gagatggaag
386941 atgttatgga tgataacgat gaaactgcta gagaaaatgc attggaagat gaatttgaag
387001 acgtaacgga tacagctggc accgcaaaga cagaatcaaa cacctccaac gacgtaaaac
387061 aagaatcgat taatgataag actgaagacg ctgtaaatgc tactgccact gcttcaggtc
387121 cgagtgcaaa cgctaaacca aatgatggtg atgatgatga tgatgatgat gatgatgaga
387181 tggacattga gtttgaggac gtttgatatg gtccgttttt tttaaatctt accaactagc
387241 tcttacaatg tagaaccaac ttttcctttc ttcattttct tctctattgt atcaagcttc
387301 tcttaaaatc taaaaaaaat gagagaaaaa aaaaagaata cgtctggaaa aaatcacatg
387361 aaaaaatttc agaaaaagaa agcggagcta ctagacatat ggcatcttta tagtaataat
387421 aaaaacatta ctagtgagaa tattgaggtg taaaaaatat tttttcgagc atatttagtt
387481 tatatatatt taataaagaa cctcaactta tagaaggcac agaaggattg ctttatcatt
387541 caaccaaagt acaaaaataa tatggtagag aaggatacat ggaaactgat aactgccact
387601 gcactattca ctgtggcagt gacgacgatt acagattatg cttggaccag ttggcaagca
387661 caaaagcaag taattgcgca acaaaaaaat aagaataaag gtgggcaaac aaaatctgac
387721 acggataaat atcatcaata tgatgaacag tttattcgcc aatctttgaa aaacaatgtt
387781 gaatttcttg gtgaggacac aattgaaaaa ctatccaatc aatatgttgt tgtcgtggga
387841 gcaggtggag ttggatcttg ggtggttaac tctttggtgc ggtccggatg ccgaaagatc
387901 agggtcgttg attttgacca ggtctcacta agttcactaa atagacacag ctgtgccata
387961 ctaaatgatg ttggcacgcc aaaagtggaa tgtctacgaa ggcatatgcg ggaaattgca
388021 ccatggtgtg agattgatcc gattaatgaa ttatggacgt tacaaaatgg cgaaagactg
388081 acccttggta atggaactcc tgactttatc gtggactgca ttgataatat tgatacaaag
388141 gtcgacttac ttgagtttgc ctataatcat ggtatcaaag tgatctcttc catgggtgct
388201 tccgcgaaaa gtgatcctac aaaacttaat gtgggggact tggctaccac ggaggaggat
388261 cctcttgcaa gggtagtgag aaggaaatta aagaaaagag gtatcttatc cggaattcct
388321 gtagtattta gtgccgaaaa accagatccg aagaaggcta aattattacc cttaccagat
388381 gaggaatatg aaagaggaaa ggtcgacgag ctgagcgccc tgaaggactt ccgtgtaaga
388441 atcctacccg ttttaggtac tatgccaagt ttgtttggat tgaccatcac tacgtggatt
388501 ttatctaata tatccgataa acctctagaa cctgttgagg gtaagaatag aattaaggta
388561 tacgatggta tatatcaatc gttggcaggt caaatgagca gagtcggtat accgagccaa
388621 agaatcccat tggctttgaa ggatgttagt taccttgtcg aagaggtgtt taagggtaaa
388681 tctccaatta gcggcatttc cactagacta actttaacca aatgggatcc ctctaaacct
388741 atctctttgc aaaatgtggt agtactaact aaaaacgaac agaaagtgca cgaagaccgt
388801 gtcttgaagg gtaaggaaag cttacaagat gtttatgatg ccaaagttct aaaactggtt
388861 tcacaaagat tcagagaaga agcttattac tctcaattca gatgatcttg ttcctttcca
388921 acatataaag cattttcttc catagagtta cgtactattc caggaggctt ttcggactca
388981 taccatatag aaaactattt ttatgcttct tcatttactt ctacttgttt atgtttattt
389041 gtaaaattac attatttaat ttcttgaaag taaaaaactt gaatttctga aataaataaa
389101 aactagagaa aaattaacga tgaggcatgc gacggaaatc aatattgaaa cttctcaaag
389161 ctgaaccact gaaagggttc tttaggacaa ttttcattcc cttaatcaac aaaaaatgac
389221 taaaacctac atattcttct tagaaaaaat acatacgcaa aacaagatag aagagcaact
389281 gttgatacga tagcaagggt gacagagact attcaattat atgtctttta ttttcattct
389341 tatcaccact tttccgtttt caacttcgtt gaccgcaaat taaatctgtt cttctggtgg
389401 ttgattcagt aattcttcga ttattggaca aagctctagt ggcctagtca tgcatgaaaa
389461 ccttttaacc accttcccat ttcggtctac cacaaacttt tcaaaattcc attttatcat
389521 ttttattcca gacttcccgc ttactgaatt ctttaagaac ttgtagacgg gatcttgctt
389581 ttgcccgttg caacggatct tatgtagaat agggaaggtt acaccatatt tatcttgaca
389641 gaacttatta atctctttat ccttctcgaa ctcttgattt ccgaattgac cacagggaaa
389701 ggccacaatc actagaccat gtgatttgta tttttcgtac aagtactcta attccttgta
389761 ttgaggtgtg aacgcacaat gagatgctac attgactatc aaaaccactt tgttacgcag
389821 ggagttgaag gggaatggat ttccgttttc atctattggt gaaaaagaat aaaattcttg
389881 catcgttact tataaatatt gtgtttctcc gcttatattc cttatacggg ttcacaatca
389941 gagaacctcg ccgtgcacaa tatcacctac atgactaaaa tatatttgta cattactgtg
390001 ttatataatc acttaatatt gttcaccata agcaatctct gtagtagagg tgagccccgg
390061 ctttaagttc tcttagatgt ggcgaacaag ggatgaatcg cttaccctat agaattaggg
390121 aacagaaggg gaaagcaaat acggaaaatt ttccacatga agacggtagt ggggtatgtc
390181 aaggggatac taatgtataa ttaatatata tgtgtgtatc tacattattt ggtgttgttt
390241 tattgggtga tggatcgaaa ggtggattct atcaagtcct tcaactcctt ataggatata
390301 ataatacagt ttaactcatc gggcgttacc aacattaact tttcttgaat accagcgtct
390361 aatttgttca aacatcttag gacatgagtt aaatccatta ttggtttccc attcgaatcc
390421 acttgatgga atacgtagtc ataaaatagt ataatgggga atttagtccc agattcggac
390481 caatttatgt ctattcttga ttcgattcta ccaaaaatgc aatttagctt gttgaccagc
390541 ctaaataatc tgccattttc tagttctctt gataagacag actccatgta ttctgtatag
390601 gtttgtgacg attccaggac catgaacatc ttatcataaa agtgactagt aagatcatga
390661 atgctctttt tggaatcgcc gttgtctgat atcagatact tgagtacatc cttgaactta
390721 tcatcgatct gtctcatgtc atcaattgat tgaggggtta tttcctccaa tcgatattct
390781 ttaggggcag tgttgttatt agagttttca atattaatgg ataggttaaa taatagctct
390841 cctaaatatt tgtagtctag ctgttgttgt ccctctatgg tacttccgcc ggaagatact
390901 acggtatcag tatcatcatt gaacaaaagg tccataaaat tgcagtgtga taacttgatt
390961 ctccctgggt ccccagtaat caaaactttt ctccagttta atgtattgcc aatactcaag
391021 ttttgtgaat ggatagagtt tattacattg gtgagttgaa ctaaatatat ccataaataa
391081 ttattcgtta ttggaaactt agggaaatta acaaagtggt aatcatacaa agatagcgag
391141 tttgggtagt agtcaaagac caaacaaata gacagatcac caaatttagt agtttgaaaa
391201 atgtccctaa actttatcaa atttgtacaa ttaatttttg accatatctg atatattttg
391261 gatattttgt ttggattcat tgacttatcg atgttaggaa gcctcttcaa aacgtaggct
391321 ttaccgtcat aattggaaaa aactttgaag agcgtagttt tatttaaaaa atcgttatta
391381 ttgaagttca atggaaccaa attaaaataa tcttgtacaa tacttggtat aactttacct
391441 gaagagggga aaacctgcaa aatcgataag tttttcttgg ttaaatcttc tctaatattg
391501 tttggaatga aaagctgatc tgcagacctt tcattaggct ttaataatga tttcaatgat
391561 gatggctgtt caggtgcata taggtgatac tgtagaagac tgtgaggagg cggataaata
391621 cgtgggtact taagattact actctctatg ggtggcggtt gcataggagg tggcacatta
391681 ttagccatac tcatattgtt actattatca tcagtggcgt ttatatttat gccaccagaa
391741 tttgcaatgg agggaaatgg aaaagaatgt gcatttgcat tagtgtgaat tgaggaggtt
391801 gaagacggag tgaaaatggg ggcattgaag gggtcgtaat tggaactcga agcggtagtt
391861 ggtattgata tgcttatatt actattattg ttattgttat tcactaacga gctattaact
391921 atcggattaa tcatcggatt aactgtagaa gcagtagcag aggtagctgc catggcgata
391981 ttgccagtag catttgtagc agcggaggtg gtattcgtca cagtggttaa ggagtcacta
392041 ccgactgtca tcggagtgaa acttgcggat actttagcat tgaacttagg aactgatgtc
392101 atggtcggag ttgtagcctc acccacatct attggaggag gaacgtcatt tatggtagta
392161 gcggtagtgt tatcgctgtg tttgaaaggg caaccttctt tctccttttt gcagtagcca
392221 taaatagtga tatttctgca cggaatatcc ttcgcccaat caggattgat tttgtccatg
392281 gcgtaagata cgtctgacta gtcttttagg cttacctatc atcgaaacag tgctcccgcc
392341 attgttatta ttgctctttt aattcataaa ccaaataatt tagcagttta ttttaaggtt
392401 accctgtaaa ggtctgatat gtaggggagg gcatataatc attttaatat atatgtatat
392461 attcttacat atatatataa tatcgccgta acttatagcg taaactatat aaaatacgtc
392521 ttagtctata agctatcacg gatagcgtct tggacgtctt tgtacacatc ttcgacggat
392581 ctgtcgcaac gaacacggac gactttcgat ttggtttcaa agtactcgat gacgggcata
392641 ctagtctcct tgaaagtgtt aaatctcttc ttaatggact caatgttgtc atcgcttcta
392701 ccactggtct tgccacgctc caatagtctc tctaacatga tatcttcagg gcagtcaaag
392761 aacaggatga atttgctttc aacgatgtct ctttcaaagg aaatggcttg atccatcttc
392821 ctaggaaatc cgtcaattaa gaacttatgc ttgttcgcct tgacgttatc ggaaatagcg
392881 ttgcgtaaaa gcgccaaagt aatctcttga gggacaatct ggccctcttt gatgcagttc
392941 ttgatcaatt ccccatattg ggaacctgct ctgccctgct cagcacgtag aaggtctccg
393001 gctgacaaat ggacaaatga atagtcctta actagttttt cacactgagt acccttgcct
393061 gcaccgggtc ctcctagaac gaagatcacg gaaacttggt caggcgagaa agctggctgt
393121 gatgtagtgg cagctgtcat ttgtcttatt caagaaattc aactggttcg ttcttttgat
393181 agtttaccga aataactgat gtcacgagtg ctaaagttcc tacgagtacc aacaatttgc
393241 ctttgtgttt acccttgctt tgacttttgt tagcgcgtgg tacgtttacg ttggtcttcg
393301 aaggtgctgt attgtggaaa gttggttttt tcgaagaata aaatctcagt ataaacctgt
393361 agcgtggatt cataatataa ctaagctaac ataaaaacgg gagagggtgt gtgcgactaa
393421 aggcaaagac aggaatgcat cgctttaaaa gatcaccata actacttaaa agtttcgtta
393481 acgtggtgaa aaagaaaaga aaaagaaaag tgaaaaaaat aaacctaggg ttgaaaatat
393541 aatcagttag gtgtcatgat attgatacat ttatttctat aggtctgaga gtactaactt
393601 agggtatatg aggggtgtta agttgggatg atgacgcatt aattaagagt tcattatatg
393661 aggatattgt atacaatgca agaatagcgc cccaatcccg gccaggtata acgtgcaagc
393721 atgaataaag aagaattatt gggttttcta ctagatgaca gtattgatag ccaaaaaaga
393781 tgcgtcacgg atcagcaggc ctactctaat tggttaaaga atgataatga tgaacgtacg
393841 gcccatgagg aaagctcttc acaaagtacg atagccgcat tgaataagaa gaagcagaca
393901 gaagctgctc aagaagatat agaagaactg ttaaacggct tagaaggcat tattggagga
393961 gccgaccccc gtaatctcaa gagtaagtca aagaggaaaa ccaaaaaggg cggatcgaaa
394021 ccaagggaag aaaacgtgaa tacggagaaa catattgtaa tgctcgaggt agaagatttt
394081 agtgatatga gcacccacga agatgtcaac ggagcaagtc cgtcgccaaa tctggaccgg
394141 tcgaagaaga atgagaagcg aaggaaaaac gccaaggagc tgtcatacga tgaactaaaa
394201 gacaaactag aagttaccac tcgcaaatca cgtcttgagt gcaaagactt gaaaaagaaa
394261 gttcatgggc tcgaaagaag gaaccttgaa cttgaacagc gtttagaaga gctgaagatt
394321 gagaaccaga ctttgataga gattaacaat aaactgttga aaaacactaa tgaggatgag
394381 attaacaaga gccagaggaa caaggagaag gaccgaaagc ggagggaaag aagaacggca
394441 aggagaaaag atgaaagaaa gcaggaaaaa aagcaggaaa aaaagcagga taataaaaca
394501 tctcaatctt ttccttcctc aactgacatg aatggacagc ctatagaatt ttgaatgcat
394561 tctaatgaca taactatttg acgacgtgaa ttagaaacac atacttttac gtgtggctgc
394621 ctctaagaat taaacttctt ttctttttat tcttattttc tttaatgaat atatacgcta
394681 tacttgtact aagtcgtgtc tttattcctc gcccgccttc gtactttatt ccagttccat
394741 atctgcgtca aaatcatcgt cggcattatt acttccagtt ttgctgtcat gacctccctt
394801 tcttagagct ttgttattct gatcaaagat ctccttttgt gttctcaacc ttttagccat
394861 gttgacaggg tcataagtca atgaagatct ttttttattg agcgaagcct tgtccttact
394921 tgcctgactc attaaattcg acttgtcaat aagtgggtgg ctggcatcca atgataacgt
394981 cacgtttagc tctagggcat ttttcaaaag cgctgttgca gatgaattat taggctttag
395041 gtacaatgat ttgtgcaaat gatcaatggc cttttgtaat ttcttcgtct tcaaatataa
395101 gtaacctaag gaacaatgaa tttcagagtt tttatcattt ttctccaaaa cgcatctaaa
395161 acatttaatg gcaatttcgt tctcatttaa ctttctgtaa gtgtgtccta gatttaattg
395221 aattgatatt gtcgttcttg aacttggatc aagatctttc accacttcca acgccttctt
395281 caggtatttc ttggctttga caaattcgtt cttcttaaaa tacattacac ccatttcatt
395341 gagtactaat ggatcgtttg gacaaatgtc atatgccaga acaaaatacg attctgctaa
395401 atttaatgaa ttcatcgcca taaactgcat cccgagaaac agttttggta agtgcattcc
395461 aggaaagaat ctggaggctg tagagtatgc tgttaatgct tggtcttgtt caccttctag
395521 ggcatacgtg tgtgcaaatc ccagccatgc ggcagcaaag cttggatcca gtattgagga
395581 tttggaatag tatttctgtg cttcactaat tctgtccaag ctcatataat aggtcgcaac
395641 gctaaaccat gttatcgcag acttcgggaa agtttccgct aatcgatgcg acagaaggaa
395701 aagcttattt ttatttgata gttcatatag acatccaatg tatgctggca agatattcgt
395761 attaaattcg tcgttttcca aaacggtctc gcacaactct aagcattcgt tgaatttgca
395821 ttgcgtatag cagatatcca ccttacttct tacgacatct acattgtcag ctaatttata
395881 atctttcgct aaaatctcat tggacttcgt tatatcttcc gtgttgatgt atttagatag
395941 gttgatctta taaagattct tcataatctc tttatcttcc ccaaattctt tgaaatccaa
396001 agagtcaaac aggtcccatt cctcttgtgg agttaacagg ttcttggaca ggagcatttc
396061 gaaagcttca aaatttttta tatctaccaa aatcgcttca cgaaatgcat cccttgcctt
396121 gttaaaatta ttttgtgcaa aatatatttt ccctctcaga aaacataatg atgactccat
396181 ttttataccg ccgtcagtaa ctggctgtga cgtattgctg ttattgccat tattgctcat
396241 ggtgtttgct gccgtcgtag atgggtcctc gctgaatgga ttgtattcgc ctataacatc
396301 tagagcgtca tcaaatctct gtaatttaac aaaggagagt cccaacagat atcgacacag
396361 gatattaacg ccatccaagt tgttcctggt aataagttct acagccctta cgtactgatt
396421 attattgtaa tatacttggc cgagccagaa ggcatcatca ggatcattgg atatgttata
396481 cactttatca gcaatatatt ctgcggtcct atacatatgc tgcatcaatg cgtcgaacct
396541 ccaaagtctc aatctttcta tagctgacaa ttcagaaaca tctagttgag ttgctgtagt
396601 tgttgtcgtt aatgttgttg tcgtcaatgg cccattatgc cctagtttac tctcccgatc
396661 attattagca ttcgcagctg catcgccatt gttatgaaca tcctcatcat tatcttcatc
396721 acgaaccaca ccatcaactg aatccttata ttcacgctgt aagctcacct tccttaatgt
396781 ggacggtatg gtagaaccga acatactatt cttagacata gaagctaaca aattattgtc
396841 gttcacaaca ttgcccgtaa tggaattgga attagaatta gaattagcag atggctggtg
396901 cggagtcata atattcgctt gcaacttctg tattaaaggg ctatttgcta acgactggta
396961 gggactcgta gccgtattgg ttctgttcca gggttgctgc aaacgatcat tctgagcatc
397021 ggttggtaaa ctctgttgtg ttcttgctgc agatacgtta gaaacaaatg gcgaggcggc
397081 caatgtagaa ttatgttgtg aatgttgctc cgaaggcgac atggggtttc tcataagtac
397141 cctgtttgac gatttcaagt ttgatgtggc ttttgatgac ttgtaataat gtgtagcctt
397201 tccacaaata acgatataac aatgacagca ataaagacaa aacttcatat catctttaac
397261 gattaagata aattatttta tattatacat ataaactaac tttagtacgc aacaattctg
397321 agctgcacgc atgtataagg cgtttattca agttctactg atactttact cttcttcaat
397381 tgcttccgct tctttttatt gagtttcttc ttctcaccaa acattatctt ctttaattct
397441 tcggtatcac tttccacctc actttggtca cctatatcag ctgtttcagc atccctcttc
397501 ttcattgtgt tgtatttctc aatgctttca tcgcatagcg ttaagcaatt tagcctttcg
397561 ccacagtcgt agactgctac ttgttctttt gtagacatat cccatacgac aattttacca
397621 tcagaaccaa tggtgactag gtaggtacca aattcattcg tataaaactt gaaatcttta
397681 atacggtttg tgtgacccaa taaagaaaaa gcggggctga tatcctcctt gtcgtcatca
397741 tcttcctgct tttcattttc ttcaactttt tcgaataact cctcacaagg atagaaatga
397801 acattaccat cgctgatacc aacagaaagg tattccttat tatcgaatgg taaaatatgt
397861 gtttcaatat gcataagagt tttcctttga aagactattt ctttaaaaac tttagccgat
397921 ccagtttcat aaataagcac cctatccctt aaacccacgg caaaataatc acctttggcg
397981 cctaaccatc taacacaagt cccgtttgta ttatattttc ttagttttag tacagcagca
398041 tttcttagag tcatcaaatt ccaaagacgt atagaatggt catcactaac actgatggca
398101 attctattgg tggggtgaat atccacatca ttaacccttg ccgtgtgtcc ctttaaagtc
398161 cccactgttt cccagtcctt tactctccaa accataattt tgtggtcttc tgatgctgat
398221 aataaccatt tgctattctt gctccccttt gaaacagcag catcctcact ggaagaagct
398281 ggatgtgaga attgtagagc agtaatagag ccctgatgac ttaacaaagt acccagttcc
398341 ttcctctttt gcaaatcata aattctgatg tgctcgtcat tggatccaga aactaggtat
398401 cttcttgaaa cagccaaaca tttaatactc aacgaatggg cttgaaaatg aaatattggc
398461 ataaaatgtg gtgtctttgc tgcatcattt tccttttgat ttgggatatc taaggataaa
398521 cacaaaatgt tgtgctcgta tgagcccaca atgatacgaa attggttctt gtcgcctata
398581 gcactcattt ttctacacga attcttgact tggcccttag gatcttttcg agatgaggta
398641 ccatgagttt tcaatttttc atgttctaaa aaattttcgg ccttgatctt gaactttata
398701 attctaagca aaaaaaaaat gaagacagta taagtagtat tcagtaacat aaagaagata
398761 aaattcaaaa atgcaaaata ataaaaaatg aatctatata gtgtaaggat tatgtagcta
398821 gaaaaatgtc tttaattgac tcgcatgtcg tttagaatgt tattgttttg aaacttcgat
398881 aactgcattt taaaagaggt tttcatcctt tcgttgccta gtagtacctt ggctaaacca
398941 attcttaaat attcctgaac aattttggat aaattatgaa acatatcatc atctttcccc
399001 aaattcgata atgtgaaaca taataagagt actaaagtta aggggatcca aaagaatagg
399061 agcatcttat cattctgaaa gttttgcttc ttggaaaaga ttgtgttgaa cccgacctgt
399121 aaagcttcta attcatcgtc ttcagaagaa gtttgagaat catccacggt catttgggca
399181 gaattatctg gcccaatctc cacagatttg ctaccaagtt cccagttttt gggttttttt
399241 gggaacaagt cttcatactt tgggagctcg tcatttaaac gagttagcat tctgttccat
399301 aaagatccgt caggctctat gctagtctta gtagtttttg gtatttcatt tggctttgaa
399361 gagaagtcct tgattttgtg ggtgttaaag aactccaaag caatctcatc tgaagatgat
399421 tcacaatcac ttatgtcata acctgaatcc gaatctagga ttgagaatga cgtattgtca
399481 ttacagttgg attgttcggg ggcaagggca gcggaatccg ccaataaata ttttctttct
399541 tggacatagt catgatcagc atcgtcatca tcaaataaac ttgagttgaa acttgactgg
399601 gatacatttc tctcaaacgg ttgagtatca ctggatcctg ttgtattctt cgttaatcta
399661 gtcagaatgt cgtcaaacag actggtttca taattagaat atctggtctt gttgacagta
399721 taattcatca ggaagaactg tttagcgata aagccgtttc tggttttctt cataatatta
399781 acgttgcatt ctaacaatag tcttataatt ctcaagtcac cattaataca cgccatatgt
399841 agcggagtaa aaccaaataa atcttggtcg ttcaaatgcg acccatattt gattagtaat
399901 gagacaagac tataccagtt attgaatgct gccagatgta atagagttct acccctaacg
399961 tcacacatgg aaagattgac ggtagagaga ttattatttc tcttaaatga cttaataact
400021 tcagtgatca attgttcatc gtttatattt cgcatcatat tcgtgtacga atttaaagag
400081 ctattctgtg agtgtaatcc tgcgttatta ttagatggag atgaatcact gccaacaatc
400141 cttttagcaa tatttcttgc atcttccagt ttaccgttca ttttcagccc cacaatttgc
400201 agagccaatt caattagttg cctatcagta tcatcaacat aagtaaagat tgctttctca
400261 ccggtatact tgtttaagtg cagaatgtca ttggtactat tgctggtgga aacactacta
400321 ttgctattat ttctcataga cgtttcactt gggtcgacta tggttaccaa aaccggtcca
400381 ggtttagatg aaggcggtaa ataagtcacc atcgtagatt cattccagca ttggctggac
400441 aatgctatat tttcgccaaa cttgatgatt aagccctgct taaactttga gccaagtaga
400501 gtcacttcta tacctccgtt gatggaacct tgtgcgggga tgacacgctg aatagaaggc
400561 ttgttattta gcgccacggg gacactatta tggttcgata tatctttgga agaatcgatg
400621 aatttctggg gaagacggga aaacgtatta ggcgtagaca taaaaggctc gtttaccgaa
400681 cgctgcctct tgccagtgtg tctcgcagag gccgcactga aatcactagt taatgtagta
400741 agagcgggat tagatgaact attaaaacct gtggacgacc aagagtctag tgaacgatgt
400801 aaattgttgt cgttgttatt agaaaaatga atatctgaaa aagaatggtt gctgtcctca
400861 ctggaggaat ttggtgatgg aaagtgtctg ttgttgttca tcattgcggt attagtctta
400921 atgttgtttt tgttatcatt atcattgttg ttgttattac aattgctatc aagcatacag
400981 ttcgtagaaa tgacaaaatt tttactgtta gaaggcaggg ggaattcgga tgggaagttt
401041 aagtcacttt gcggcgatga aaaggatcta gtgtcatttg tcattggcga aacctgggca
401101 ttgctggtgc tggttggagt tgtggtattg ctggcatttt tcttgtccat gatcattatg
401161 ggatctgtta tagttttcgc caagatatcg ccgttatggt cccttagaag gaacaaaact
401221 acaaacccgt tagttgcctt gtggtgtctg cagtaacaga cgattctcgt cggtaagtcg
401281 aaattgatac agttagagtt accactcaaa ccgttattac taatgatgaa aagttgttta
401341 ctattgaata tgattgctct tttgttttcg ttattttgcc agatggagtt gtcgttcaac
401401 ccagactttc ttctcgacgc tcttcttttt tccctgttga tacatctatt acaaacatag
401461 gtctgcttga agttgttgct attgttgtta gatgcacaca aaagaaaggc gtccaagaaa
401521 agagtccttt cgttgatgtc cctattgggt attgtcaagt tggtgggatc gtccgagctg
401581 gtgaaaaact tgtccttcgc tatacaatca gagggcagat gaataaagaa gttttttctt
401641 gcatgtgcgt ttctaatccg aaaactcagc ttcatctgag tttccaccct agaaaccttc
401701 ggcaacccaa taatttctag agacaatgga agggactgcg ggttaatgtt gataaaatcc
401761 agtggattcg cgtatggcgt cctcagaggt agctttctgc caaattgaac gtgtcgatca
401821 agcaatcctt gcaaagatgc gatgtcatcc ctgagctccc cttcatcttc cttacctggt
401881 gtagtagtac ctgctgttat cattttctct tggttcagac tcaataaacc agggtcttgc
401941 agagaggacc cagagttgag cagagcaata tccagtaatt ctgattctag taaatccaag
402001 tccggagagc catcgttgtg ctgtatgttg gcgctatagc tgtggagcat cgaggaaacg
402061 tttcctgtgc cactcatcat tttcagtggt gtactactgt tgtgattagt cgtttagagg
402121 atatctagag tataattatt ttgaatgagt ttcgttgaca ttttcagttc atgcgatcat
402181 cttactttca tggttgctcc ttgccgttaa aattgaaacg aaaaaagcgg gaatacaaca
402241 atgtcacctt acacgagcag agaaaagggc agcaatagcg acaataaccg ataatgccag
402301 gccttccaga gccctatgct gacctatatt catcatgacg ctatccatat gcaactagag
402361 acctgctggg aagcgctctc tcatttttga aggttgcagc agtgctcgcg ccggttttcg
402421 attgggcctc gtgataaaac acatcagcaa agtttcgctt ttgacattct gttaaattgg
402481 tccttaactg ttggtgcaga cctactgcaa gactgttaat tatggtatat tatatatcaa
402541 gtgctgatac aacgtacacc atcgaaaatg gaggagtacg attattcaga cgttaaacct
402601 ttgcccattg agacagactt gcaggatgaa ctgtgcagga ttatgtatac cgaggattat
402661 aagcggttga tgggactcgc aagggctctg atcagcctta acgaactgtc acccagggca
402721 ctacagctaa cagccgaaat tatcgacgtg gcgccagcct tctacaccat atggaactac
402781 cgattcaata tcgtcaggca catgatgagt gaatccgaag acactgtctt gtacctgaac
402841 aaggaattag actggctaga tgaagttacg ctgaataatc caaagaacta tcagatctgg
402901 tcctatagac agtctctttt gaagctacat ccgtctcctt ccttcaaaag agagctgcct
402961 atcttaaaac tgatgattga tgatgattcc aagaattatc acgtttggtc gtacagaaag
403021 tggtgctgtt tgttcttcag tgactttcaa catgagctcg cctacgccag cgacctcatc
403081 gagacagaca tttataacaa cagcgcatgg actcatagga tgttttactg ggtgaacgct
403141 aaagatgtca tttcaaaagt ggaattggcc gacgagctcc agttcattat ggacaagatt
403201 caattggttc cgcagaacat cagtccgtgg acctacctcc gtggtttcca agagctattc
403261 catgataggc tacagtggga tagcaaagta gtcgacttcg ccacaacctt catcggtgac
403321 gtattgtcac ttccaattgg ctcaccagag gatttgcccg agatcgagtc ctcatatgcc
403381 ctggaattcc tggcatatca ctggggggca gacccttgta cccgagacaa cgctgttaag
403441 gcctatagct tgctagcaat caaatacgat cctattagaa aaaacttgtg gcaccacaaa
403501 ataaataatc tgaactgaat atatgtaagc actctatttg tacgaatata tttacgtgtg
403561 tacgtgcatg cacgcaagtt taatctagtt ctacaaacct actgctgtat tgagattgat
403621 ctcttcccct tcgttttgga ccgctatcat tgatgcgtcc aaacccgtcc tcgttcaact
403681 gctttctgaa aaatttagaa cgtttaacca tcttcagcgt ccttgtgtag cacatctctc
403741 cccatgacag atatctatgt atccagccgc ccaactgata ctggttgtaa aagaatatca
403801 ttcccgtctc ccttcttatt gccgatagga gcatagctac caacgtcccc tctactaccc
403861 accttatcat tcccaacatc ttgcaatatg ttacgatctg atcttcactc tcttttgctc
403921 cttctttttg ctgtttaact gttacctaca ctcatttatt cgataccttt ttttacccat
403981 tttttcttca tgcagtttag cactagtaca ttaaaaaaga aagaaaaaaa atgaaagcaa
404041 gactaaaata tcgagcaaag cacaagcaaa tacaccgttt gtccttttag catagccaac
404101 aatgaccacc gtgtccatca ataagcccaa cctgctgaaa ttcaagcatg ttaaaagctt
404161 tcaacctcaa gaaaaagact gcggacccgt aacctcattg aatttcgacg ataatggcca
404221 gtttctactg acctcttctt ccaacgatac aatgcaattg tacagtgcca cgaactgcaa
404281 attcttggac actatagcct ctaagaaata tggctgtcac tccgctatct ttacgcacgc
404341 acaaaacgaa tgtatctatt cctctacaat gaaaaatttt gacattaaat accttaatct
404401 ggaaacaaac caatatctaa gatatttttc cggtcatggc gccctagtga atgatttgaa
404461 gatgaacccc gtgaacgata cgtttctatc gtcgtcatac gatgaatccg ttaggctttg
404521 ggatttgaag atctctaaac cgcaagttat tataccaagt ctcgtaccaa attgtatcgc
404581 atatgatcca agtggccttg tattcgcatt ggggaaccca gagaatttcg aaatagggct
404641 atataatctg aaaaaaattc aggagggtcc tttcttgata attaaaatta atgatgcgac
404701 tttcagtcaa tggaataaat tagaattttc taacaatgga aagtatttat tagttggctc
404761 ctcgatagga aagcatttaa tttttgacgc attcacaggt caacaattat tcgaactaat
404821 aggaacaagg gccttcccga tgagagaatt tctagattct ggatctgctt gtttcacacc
404881 agatggtgaa ttcgtccttg gaaccgatta tgacggtagg attgccattt ggaatcattc
404941 tgattcaata agtaacaaag tattaaggcc gcaagggttc attccctgtg tttctcatga
405001 gacctgcccc aggtcaattg cattcaaccc taaatattcg atgtttgtta ccgcagacga
405061 aacagtagat ttttacgtgt acgatgaatg actgctgcta ctgcattgat atactagagg
405121 atataatata taacgaacat tttttaccta ctgtataacg acgtatactc tatacatctt
405181 gtgtattctt tacaaataat cgtcaatgtt ggggtacctt acgtcagcgt tctcttcaca
405241 ccattctgac caacttttta ggtacttgtt accgcacctt tgcagaactt ctatattgcc
405301 aacaacaact agttgccttc tgggtcttgt catggcgacg ttcagtcttc gttcttcctt
405361 aaggaaacca acttcaaatt tttcattgct acgaactaaa ctcaatatga taacatcttt
405421 ttcacggccc tggaacccat ctacagttga tatttcaata tcagttaatt ttaattcatc
405481 atggatcaat tttttcagat gagaaacttg tgcattgtat ggagaaataa cacctataga
405541 gttctccggg acgttgaatg accttaaatt ctcaatgtgt tcttttacaa tggcaatttc
405601 gccctcatta tacttagatc caaggatagt agcttcatct gcagtctctt gaaattcatc
405661 accttgcgta tcataccaaa ttaaaggaat ttttgtatcg tcatcatcct cagatggcgt
405721 agcatcgacg gtcggtaggt ctatcaaaag tctgttcgcg accgttgcat cggccaatag
405781 tttcccatta tacattgagt gcgatggaaa ttccataatt ttttgattca tcctgtattg
405841 aacgttaaga aattttacca tatccctttt cgggaatatt ttgattattc tgtcaaatag
405901 tgtggtttcc aaattgtgaa tgacattttt gtcgtcttct gttttgattg tgggtggcaa
405961 ttgtttattg tcaccagcaa ggactagttt gtggaactga ttttgatgtg caattagtgg
406021 gatccagcat tgtggttcca tggcctgtga gacttcatcg atgatcaagg tatcgaaaag
406081 ctggaaattt ggatcatctc tataaaggga gcatagttct ctcgatgatg aaccgtgtaa
406141 agtggtgacg actattctcg attgtattat taagtcctta atggttttga actctctttt
406201 ctttaaatct ttgcgcagca gtttaatttc gttccagttt tctttacgtt gcttatagtt
406261 ttttagtttt ttattctcct gaattaattt gtcaatctcc tgggaaatgt ccttcacaat
406321 agtattcttt ttactaagta tatcaagaga gtgtctttta ttagagtcta atagcctagc
406381 aggatgaccg attcttaata ataaattatt cggcacaaga ggcgttagcc tctccagaat
406441 cgtatccaca gaaatattgg aaggcccaca aattaagatt ctctcctcag gatttttaat
406501 tagcaattgc tggatcaatt caattaatgt gaatgtttta cccgtaccag gaggaccatg
406561 tataatggtc aagtcattgt taatggcaaa attaatggca gttttctggg agtcattcag
406621 attcgggttt aaaaaagatt taatgttttg aaagctgttt gtattgggga tgaaggggcg
406681 ttcgtttacc aagtattgta taattttgtc ttgtatgggt gaactaattt cagacagttt
406741 tctcattgtg gattccattc tattatacgt gacgacattg gtagtcttta aaatgtaaag
406801 tttgctataa gaataaaatg tggtagcaat aacatcttga gattcttcta gagctatggt
406861 gatttgagta tcactcattt tgtagacaac gcctgagcat tccgcttgct cgccattgga
406921 gtcttcagac acctttttga ctttgggctt agtcttggta tttactttgg tttttgcagg
406981 gcgtaccaaa acaatatcac caaccttaat atcacccctt tgaattttgt cgttaaccgc
407041 caagttaggt cccagttcca tatataattt gccaatgaga ccggatctta tgttttctag
407101 atgtatgttg tttattgcca agccattttg caccaattgt tggatagata gcgttgttaa
407161 tagcctagaa gttgtttgaa tgtcttgttc acgttcatgc ttgatgcttg ataaaaactt
407221 agaagccaat tctttgttca tttccctcta ctcttttttc tatatttctc aagagacaac
407281 tttacatcag ccttcatatt tttgaaatat atgtaacgta caagattttc ttagcgtaag
407341 gatatgcagg cgcacatttg tgtatatatg acagtaagaa tgtttaatta taatatttgc
407401 cagttatata aacctgtgaa aaaaataata gaatatggtg cgtaatatat agaggtaaag
407461 ggtactacat cacattcaaa ttgccgaatc tgtccttgta accaggtacg tcccatttac
407521 ccttcttgac catctcttct accttagcat caatttcagg tttgatcttt gtcaggtcgt
407581 caacagttaa ttcatcgaaa ggtcttgcag attgaatatt atctaaggtg ctttgcaaat
407641 cctttaactc cttggaaact aaggattctg tctccttggc gttggtcatt gcgtgctttt
407701 caaaagactc aatcacttgt aattgtttgg aggcatcgat tttgaccggc ttatattgct
407761 taacgtatga ttctatcttg tcaatgactg aagtgttttt caacacagat ctataatgac
407821 tgaaatctac ttcggtgggt tgactttgca gctctagtaa ttgtctacgt gcctcatcgt
407881 ttctcttttt aaaactcgat aattgagtgg cagtcgaccc tgttatacgt agagaagaga
407941 tgacttttgc ccagtcaagt ttgttagcag cggatttggc caaagacata gtcgaacaaa
408001 aatataatta ggtgattctg caattaagtg cacgaaaaat ttcttttaaa tcctaagatt
408061 gttcttttgc gttacgtgtc aatatgaata tataaactta tatagaaaag tattgtacta
408121 gtagaaatat gttttacacc tacgctaagc agcaagtggt aattggtgta tcttttactt
408181 ttttgggggc atcaagacaa atatccaatc aaatcgaaga gaaaataatt cttgtaaccc
408241 gctcattagt cacgtggtca tcacgtgagc ataatatatc acgtgatata cacccatacc
408301 tcgtttatgg gattgagtca tcggatatgt cattataaac gatatttctc cgcggcaatg
408361 aggtggcgaa tattggagta aaaatgaaaa catccaccag gtgcttgatg atatacttga
408421 cttcggcggc aatttaaagc tttctaagca gcaattagta agtaaccatt acaataacga
408481 taaatacgac actggtccaa ctaactcatt gataggataa ttgcagtgat cttaacgagt
408541 ttaatggtga ccgaccaagg cagtaggcat tcgatacaat ctaagcaacc agcctacgtt
408601 aataaacaac cgcaaaaaag gcagcagaga tcttctgtcg catgcctttc ttgtaggaaa
408661 cgtcatataa aatgtcctgg tggtaaccct tgccaaaaat gtgttacgag caatgccata
408721 tgtgagtact tggagccgtc aaaaaaaatt gttgtgtcga caaagtatct gcaacaactg
408781 caaaaagact tgaatgataa aactgaagag aataaccgcc tgaaagcttt gctcttggag
408841 agaccagtga gtgtacgtgg taaggataac agcgatgatg acgagaggca tataaacaat
408901 gcaccctcaa gtgacacatt ggaagtatcc agcgctccgg cggctcctat atttgacctc
408961 atgtccaata gtaacactgc gtccgataac gataacgacg atgacaacag caacagaatc
409021 acaaataata ggagctatga tcatagtttg gaaaaatact acaaaaaggc catcagcatc
409081 tttaaacaac cagctaatgc taatggcgaa aatggcaacg gtgccaatgg tcatgaggat
409141 gatgatgaag atgatgaaga aatatcaaca aattttgctc aaagaagtgg taggctcata
409201 gaatctcaca atggattcca ttattttgtt ggatcttctt caatgacatt atttgggtta
409261 gaaattcaat ctttggttac aaagtatatt tcggtcaaga attttcgacc tttgccaata
409321 aacaccaaaa acaagatttt aaattcaaac ctgaacccgg ctataagttc ttttatcaat
409381 tcaaacaact atcttttctc gtcctataat tttttgaacc ctatatcgac tattgtcaac
409441 ttaaactcaa tcaacgataa tttatctcca ttgatgttta agataatttt gaaaagcgat
409501 acggatggta gtagtggcca ggaagaggta atacagtttc agttgccttc gtataattac
409561 acaaaactat taattgactg ctttataaat tataacgatg gttgttttta ctttttcaac
409621 gaaggcctgg ttaaatgtgg cattaacaaa ttgtacttgg aaaataaatg gctatactat
409681 gataatacca aaaaagcttt ggacaatgag aatgatccaa ttttacaagc tgtttggttt
409741 tgcaaaattt tgttaatttt agcagtaggt gaaatgtatc tgggttccat caataatgaa
409801 atgttgaaga attattctaa tcagccaaaa ttgcccggtt caaaattttt tcaaatgggt
409861 tctaaaattt ttaattgttt gttctcaagt gaaagattag aaaatgtgac taagaaaggc
409921 ggtattgaag tcctgttgtt atacgcgttc ttcttacagg tggctgatta cactttagcc
409981 tcttattttt acttcggtca agccctaagg acgtgcttaa ttctaggctt acatgttgat
410041 tctcaaagcg acactctatc caggtatgaa atcgagcatc ataggagact ttggtggaca
410101 gtttacatgt ttgaacgaat gcttagctca aaagctgggt taccattaag tttcactgat
410161 tatacaatct ctacagcact gccagcggat attgatgatg aaactatcga agagaaaaat
410221 agtcactatg ttttcagaaa ggcagaattg atttctaact gcgttactat tgtgaaaatc
410281 aatgcacaaa ttttgagcaa attatatcaa aggcaacctg agacaaacat cataattact
410341 ttgaaagttg tcatcaagca gttgttggaa tggaggaaca atttgtccga ttccttacag
410401 gtggatttta cgcaaaagga tgaagatttc aaaatatcga gattgtcaac caatatgttt
410461 acggaatatt ttcaaggaat aaacttggcc gtgagacctt tattatttca ttttgcatcc
410521 attcaattga aaaggttcaa aacgagcaat actttcgtca acttacaaaa ctattctgcc
410581 acaatatctt ccttattaac atgttctttg catgcttctg tgaatactat taggtctctg
410641 tggagtttat tacagaatag tatgcttgct atgtttagtt atatggacag agagtatctt
410701 tttacttctt cttgtacttt attactattc aacactgctt ttggtattca tgaacaaaca
410761 ctatatcatt tggatcattc tctggaaatt ttcacacaaa tgagaaactt aggcaacatt
410821 ccagcaggct taagaagagc acaattatta acattaatgg caaatttgga tttccacggc
410881 ataatgaatg acttgattac taaatataac gatattttga aatttgattc tatgaattgt
410941 gaaaacgata acatagtaga agatagcaat gaacccaaaa gagaaaccga aaagtgtaaa
411001 cctcacaaag atggcgatcg cattgaccct tcaattatag actgtgataa atcaaacacc
411061 aatacaaata tgatcaagaa cgaatctata tcgaacattg ttagcatact tccggaaggc
411121 gcgaaaccaa cgctgactga ttatagtaat ggtaataatg atgttaatga tattaacgtc
411181 aataactcgg aaccttctac tttttttgat atcataactg cgagcttgga aaattcatac
411241 caaaccacgc taactgaaaa gggctctcag gtgatggaaa aaaacatgga tcagttggat
411301 tccgttcata atctaaatga tgacgattta caacaattgt tggaggattt aggcaatatt
411361 gatcattccg atgaaaaact ttggaaggaa atcactgatc aagcaatgtg gctgggaaat
411421 actatggatc caactgcagc tgctggtagt gaaattgact ttactgatta tttaggacca
411481 taacaccatt acaaagacaa agaagaaaat actgatttct ttgttttctt atgcatatat
411541 tatacatttc gcacattata tagaaaagtg gacatttaat tcttcaaatc ttatttaaaa
411601 tatctatcac aagacagctc atttacgtag cctcttgaca acattgtcgc tatcaccttc
411661 tgtccataat attagccttt tttgtgattt gacaagctcg ttgtagccta atagtagttt
411721 ttcaattccg ttttgttctt gggctaacct caaagtagta tttaatgtac ctctgttttc
411781 gttccgtaaa gtaccaatgt tgttcagtat atcgtcctgt ggtagtctag atttgatgtt
411841 attgttcaaa acctcgaaaa acgacacaat accgtttctg ctaattaaat tcaaaccacc
411901 atcatctgct accctttgga ctttgtaaaa aataaaatag attagttcgc gtaatctttc
411961 tttcaagtat ggcatattga tcaagtttaa caaccattca aatacacctt tcttctctaa
412021 catcttgtaa tcttcatccg ttttaattcc cttacaaatg gttgttaaaa cccaactcaa
412081 ttctccatag tatatttcca tatcaatttc tttcttattg tcatcttgtt gtctcttatt
412141 gtaggacatc atcacatcag ataccatagg gatgtcccaa ctacgtatgg tagaatttga
412201 taatacccag cggtatgcct tctcatgtaa gggcgcagtt ggacttccca atagatcaac
412261 aattctagag atagaaaacc aaattaacgg attgatagga tcttgatttt gttgtctctg
412321 gtataaaatc cttttaatca acacttggta aatgctatta tatttgatta aatcgctatc
412381 agattctttt ctttcattat ccttgctagt tatttgcttt tcaagattca tctgggcagt
412441 tttcttctcc aaagaagaag ctaaatttga taaatgttcg taacttatat tggcaacggt
412501 atgacaatcg cttaatgagc aaataataaa ctgaaatatt ttgcaatcaa ggaaattttc
412561 aaattcatat ctgtatgtta cattgccctc gtcatctttg accattttta ccagctcttt
412621 gttatggatt attaatagca gtaaaaataa tggatcgtac atatcaacac cagatcgttc
412681 ggtatcatcg tagtactttt tgactaggtc acaccttgta gtagcatcat aattgtttgt
412741 attagaatcg gtatataatt cagggacttg aggcctttcc aatacgtatc tgtcaatgga
412801 ctttttgatc atgttttttt gtagtgttag tatcaacccc tccctttctt tggtaatcag
412861 cctcgtgtct ccaatggctt ccaagatttc ttcctcttcg tctttgataa attcccaaga
412921 aaaaatcatg tttgtccatg aagtagcggt gtgagattcg atagtttcta gaattttcag
412981 tatcaacttg tcgttactgg aaatagtacc ggagtaaaaa gtcaataatt tctcttgaac
413041 tattggcgtc gaatttacga ccgggtcgat gctgaataaa gagaataata tcattgtgct
413101 taagaacttt cgatacgatg aatcttcatc attgtcttta atcattattg atgagtaact
413161 gtcattgctt aataaaagtt gaaccattct ttgcgattga attgactttt tgctcacaca
413221 aaaaattaat acaataacgt attcaagaac cttaatttgt ttgatccact cactgcctag
413281 aatagcctct aattgagaat taatgatttt gacattcaac ttatttggta cctcttcaag
413341 ttttaagagc tcagccatcg ctcttagtaa ctcaaaaaaa gaattggaga taacttttct
413401 ttctgaaagg tactttgtaa ggtaaagaag agttttatgt aaccatgttt ctacccctgg
413461 ataagtaaaa ttattgtgtg cagctatgta tcttactgta gcagcatgat atttatggtc
413521 gctctgtgat aaaacacatt tcaaaatttc atttcgtttc gtttcgtcat agaaatcaat
413581 ataagtggta atcatattta atatttcgtc aaaaatctca cttttcgagg tagtgtaagt
413641 acttttcgca atttcattac catacttgga aatggtttca tgcgcaaatg cgctaaaatc
413701 tttatcctgc atgtgcttga acaaagcagc cgttgttaca atacttagta aaggtgaatc
413761 cttgatcctc cagatacttg gtatgaaaga tgggaaagaa aaatgttccc atctgtaaaa
413821 agctttcagt actagataat tcaaatcact agacacaaaa ctatttatca gagaagtagt
413881 ttctgaaagg gatagcttac ccataggatc agatgaagca tcaacacaaa ctttgttttc
413941 ttcaaaaaat ttagccaaag agatgtttac ttccttaatt gaagcaggat cttcatttgc
414001 agctttgttc agtatattct ttacaaggga tatttttata gtttttcctt cgttgaataa
414061 tttttggaga atgtttcttg tggactctag tttggtgcta cacatgagta gcgaagttaa
414121 agctgaagta cttaaatact cactaacact tgttaagaaa gcatttacat cttctttctg
414181 atacaactca ttatagttgg catactcttc gacattttca ccactaaaca cgactttttg
414241 aattatttct cggaattcca ctaattgatg gcctgtttca aagcatactg caccgattaa
414301 attgcacatg aaccttgatt ttttcatgag tagagcattt cttttttcaa tggccagttt
414361 tggtaaagcg aaatttatat acctttccaa aactttgata attgggaatt ctgtgtctgt
414421 taccatgtag ctagcaatct tgccagttaa ctcacaggca gttgcttcga accaattgtc
414481 atatacaaca gaatcgtctt ctaccaataa ctgaactcta aaaaggattc ctgccgcatc
414541 taatttgttc actggtaatc tagaaatatt cattagattt ttagatggaa gcgccgaaat
414601 atactggaaa aaagatgagc tcttcattga agaaattaaa gaattagagc tattagtttt
414661 ctttatgttt tcttcaaatg agtcaagttt caagtatata ttaacatcat gatcagagac
414721 ctcaggaaag acatttttaa caagtttatc tatgcctata tggtcttcac caatgaaaat
414781 catgtttcta agaaaaagta taagccattt aattaaaaac tctgggtttc cactcttgtc
414841 aacgtatttc cattgctctg aaaggcacat tatgaaggga gaaatgtagt tatactcttt
414901 tgccatatcg acgtacttgt atggtgtttt tacgacacga gatatagttt cgtcaaacca
414961 cttccagact tgttccatgt tgtcaatttc agaaacttga agggaaagcc cttgaagact
415021 attcactaaa gccatcactg gtgaaattaa agatatgttg aagataacgt ttgttctcgt
415081 cagctcatcg agcaagttgg atattcttgt agttatcacg ttagaagcat ttttggagga
415141 tgctagcttt aatagtaggg tgaataaaga atttccacca gaacttggat tccaccacct
415201 ggtttgagta gagttaaatt cttgaaattg taagtagttg tccagaatag caaattctat
415261 gccagaaatc ttggattttt gcatgatatc tgtgtaaata tttgatgatg gtaggttaat
415321 tgagaagagg ttggggaaca ttttactata gtagttgaat atgatggata tggacagagg
415381 taaaattcta ttatccttat tggaagccaa agaattgctc aaagtagata cgaagattgg
415441 taaatcagga attctagtat gaaactcgtt gagtaaaata gttttttcat ttctccagcc
415501 tttttgatca taaaatgtgg aaactttttc taattttttt aacgctagaa ctattgattg
415561 acaggctaat tgtcttatga tgggtgtttc aaattgtagg gatttaacca acgaggattt
415621 ggtgagcaaa gatggcagaa tgttttctat aactaatgaa gtggcaggtg gaatattgct
415681 atcaactttc tccataaatt gcggtatctt aagattaata atcttgttaa tcagtaacgt
415741 tataccaaac caatacgaag tcatcttagg gtcatagtta ccattcgtcg ttaaaaagat
415801 gctgtaagga gcaacaagtt cgggaacgtt ctccaatatt ttgatcaacg tacctaattg
415861 cagcgtatct tcccaaggtt tgaaaaggcg taaagtgttg aacaaaagtt tattatgaat
415921 ttgaaattcc acttggttga cggttatcgg agctccatga gaagctccat cagcaactga
415981 atttttgaac caaacgcaat tatcaggaaa tgctacgcta aagtcacggg aagctccaaa
416041 agttaagaaa aactcatttg ccttcttaac caaattcttg tttgatgaat aataaaagtg
416101 atgaatcttt gaagccgcta gttcatttaa aattttggtt ttagtagttc tcttgaagga
416161 tttctccttt aaaatgtcgt ttatgaatac cgatagtatg tgctcagata acttgtcaga
416221 atcagcctta ttcatgaatt taaataggtt gctcataatc ttaaagtttt ctgtcaaaag
416281 ttcttttctc acgaatgggg aagcatttga gatcaatgtc aaccaaaact tgataaatgt
416341 aaatcttaat gagtcatgtt tggatgaatc agcagatgaa ttcccattgg ctaactcaga
416401 cttgcttggt accaacagtc ttggtaaaat aggtaatgaa aaatcgaaat atgaaactaa
416461 ttcctctata tgttgcccat tgttgaaatt gactatttgt ttgagtagac gaagaattgg
416521 attagttaat tgcgcacgca tattgttcaa ccctctatag agaacttttg tgtaatcggt
416581 caatatcaat ctaattagac cgctcccaat agtcactgta ctagtatcag atgacaaaac
416641 tcgtaaggtt ttagtcagta atgaggtagt tttcgagaat ttcccatggt tatttacttg
416701 agcataatat gaccaagtct gtaccaattg agcaccaaat cctctttgga agaacactat
416761 tagaggttgg taatctttgg agagagtttc atcttcgact gcactgatta tactttctag
416821 tgtttctaat gtaccgtctt cgaactcttt cccttgggtg tacttctccc ttctctggtc
416881 gcgagatcca taggcttcgc tatgattact cattatgtaa gtgctcctct agttctgtta
416941 gatgaagtag taccgcatag attagagaaa taatatccaa tcaagaatat aaccgaacta
417001 ttctttgcga tgagctttat tgctgaaatt tttcatattt cgtctacagt gatataatat
417061 tgaaatcctc atgcaagtcg tgcataggta aaagctgttt actatatgtt ggtgcactat
417121 tatcatataa ttttagtttg gtcgtatact agtgcggcag taataataaa tgctttagaa
417181 tcttcaatct tcatttgttt acgtaaaatg aaaacgtttt gtgttagaat tgacagattg
417241 aagtttaatt ttaggtgtcg ggagaaacat tttaatccct ttttatgaat ataatttaag
417301 tactaaaaaa atcaccataa ttatacaaag taactgcaat ttaaaagtac gtttataatt
417361 aattcacata cacatgttat tgtatctaac taaatagtct cgaaatagtt caattgagta
417421 cgcaaactaa cacagtcagt acagatcgta aagttttccg tcaatagggc cctgacggag
417481 aaagattccc tttcctatat taggaatcta atagacaaat tcatcaagat atgcttccgc
417541 aacaaatctt gctctggcat tcaaaaacag tttaatttca ctgatttcct tatccacgtc
417601 ctccatgaat tcaataataa aatcaaccaa tttcccagtt ttcattgatt cagtatgctt
417661 attagttatt agaaaagaaa tactgtagcc aggtattggt acacgtctca gaatgtagaa
417721 tgcttcagca cgctgttcca aaaatctagt aaacttgtga actaaaatct gctcaatttc
417781 atctgcctgt ttcaccatta aactcatacg caccgagttt acactgggct caatcaatac
417841 ttgttcattt tcattacgag atatatgcat cggttggagc aacaattcgg cgctagtgtt
417901 agggacttca acttccggtc tgttgtgcct ctccacttcc tgcgaagaga aattgctcaa
417961 agtcaacgca gcttccaggg aataacgaac agccgttaga tacggacgta atgattgtga
418021 catttcctac tatcagttgc ttcctctttt atcttttgtc aaagtgacac cgagttgttc
418081 cgaaagcctc tatttgcttg gctttacagg ctttttttgt tctataattg tattttgcta
418141 tacaaaaggg gcgacgtggt aaacgatatg aaattatcga caataataat gtacttggaa
418201 atctggcagt tgatgacatc gcaatagcgt gcctacctat caggataaca aggtctgaag
418261 ccagatcgac cactagacaa gcattgccgg aggtgggaga cgtgaaacta tgtctatttg
418321 gaaggaagct aaagatgcaa gtggaaggat atattattac aatactttga caaagaaatc
418381 tacgtgggag aagcccaagg aactaatttc tcaggaggag ctacttcttc gagaaaatgg
418441 ctggaaggcg gccaagacgg cagacggcaa agtatactat tataatccaa caacaagaga
418501 aaccagctgg actattccgg ccttcgagaa gaaagtagaa cccatcgcag aacaaaaaca
418561 tgatacagta tcccatgcac aggttaatgg aaatagaata gcccttacgg ctggagaaaa
418621 acaagagccg ggacgaacta taaacgagga ggaaagccaa tatgctaata actctaaact
418681 gcttaatgtc aggagaagga ctaaagaaga agcagagaag gaatttatta ccatgctgaa
418741 ggaaaatcaa gtagactcta cttggtcatt cagtagaatt atttcagaac tggggaccag
418801 agatccaagg tattggatgg tcgatgatga ccccttatgg aagaaagaaa tgtttgagaa
418861 atatctttcc aatagatcag ccgatcaact tcttaaggaa cacaatgaaa caagcaaatt
418921 caaagaagcc tttcagaaaa tgttgcaaaa caattctcat ataaaatatt acacccgttg
418981 gcctaccgca aagagactaa ttgccgacga accaatatac aaacactccg tggtcaatga
419041 aaagacaaag agacagacct ttcaagatta tatagatacc ctcatcgaca ctcagaaaga
419101 atcaaaaaaa aaattgaaaa cacaggccct aaaagaacta agagagtatt taaacggtat
419161 tataacaaca tcatcctctg aaactttcat aacctggcag cagcttttaa atcactatgt
419221 ttttgataag agtaagagat atatggcgaa ccggcacttc aaagtcttaa cccacgaaga
419281 tgttttaaac gagtatctga aaatagtaaa tacgattgaa aacgatcttc aaaacaaact
419341 aaatgagctc cgactgcgca attataccag agaccgtatt gctagagata actttaaaag
419401 cttattaaga gaagtgccaa tcaaaatcaa agcaaatact agatggtcag atatttatcc
419461 tcatataaag tctgatccgc gctttttaca tatgcttgga aggaatggct cgtcctgcct
419521 tgatttattt ttagattttg ttgatgaaca aaggatgtac atctttgcac aaagatcaat
419581 agcccaacag acgttgatag atcaaaattt tgaatggaat gatgccgata gcgacgagat
419641 caccaagcaa aacatagaaa aagttctgga aaatgaccgg aaatttgaca aggtggataa
419701 agaagacatc agtttgattg ttgatggttt gataaagcaa agaaacgaaa agatacaaca
419761 gaaactccaa aatgagcgta ggatattgga gcaaaagaag cactattttt ggttactttt
419821 gcaaaggaca tatacaaaaa ccggtaagcc caagcctagt acgtgggatt tagcttccaa
419881 agagcttggc gaatctcttg aatacaaggc actaggcgat gaagataaca taagaagaca
419941 aattttcgag gattttaagc ctgaaagctc tgcaccgact gccgaaagcg ctactgcaaa
420001 cttaacgttg accgcgtcaa aaaagaggca tttaactccg gctgtggaat tggactattg
420061 attctgacgt gtcgacctct atcttgttaa tcattatata aattatacat agagattaca
420121 tgttatttca agtttgcgat caccgcacaa tttcttagtc attgttgtaa gtgttctgca
420181 aaaatttcag cttttgtacc ttattttcac aaaattcaaa cacctgtccg aactgtgttt
420241 taaccagtgt ttttgaattc aagagttcag taatactttc ataatttttt aaccactcca
420301 tccaagacaa acaatggagg aatgaatctg ccaaatcgtc atcttttctc acccccgaat
420361 tatcttggat ctctagtata tcacatagct tgaaactttt ttttttggta agggcatttc
420421 ttatcctatt attccaaact cctatgaact cgaccagttt tgtagaacta gttgaattac
420481 cttctagtat tgaggttgaa agtatttttt tcactagctt tattcgagaa tctttgctat
420541 gtttgttaga ttttaacttt tttgaactgg tcggtgtctc ttctcttgga atgcaccaat
420601 atgaagtcat ccgatgtgga tcggacgaac ataccatata cctcaacttg gacgtattcg
420661 gtattttatt cgtatacttc attttatttt ccaagttaga gaaaagaatc tgttcgagaa
420721 tattcacttt taaaattggg tctaaaatat gcctcgaaga catagttctg gtacgttgcc
420781 tttcaattgt aaacatatct ggtatcggca tagattcaaa taaatactcc gtaaggttaa
420841 atacaagctc agaagtttca gcaggattca agcttaactt tttgaggttt tgaaaaaatt
420901 tctcctctag atttatcttt tgccagtcta gtactttagg gagcggatca ttattgagca
420961 attgcatctt agagaaagca aagttagaaa caccagcatc catagacaat atgttaattc
421021 ttccctctct tatcttttgt tgtcgtaact tctccaaaaa ttcacactgt tcttgaatgt
421081 aggttctttt agcttctttc gtcgtgccat ttactgctcc aataacaaat gataaagatt
421141 tcagttgtgt gctttttgca ttttggcagc aggaatcgat gagttgcaat atcttagctt
421201 tctgtgctgt cgacatatta ctatcttttt tagctttaga ctgtataacc gtaagccttc
421261 gttgtatgca atggataaac aaatatggaa tcgccagttg aaacaaaaaa atgagaaaag
421321 tacggataat ccgaagaaat ttagtctgat tccatccatt ttttgtatct taagaaataa
421381 ttttgaagtc atataaaact taaatagaaa aagtaactaa aatttaggaa agtagaaaag
421441 ctcctgcacc ctcttcaatg gcttgacaaa gacgagaccg cataatatct ttgctagtat
421501 acttcggcaa tttcaaataa ttagcacatg tcattacact tggtagatat tcgtctgctg
421561 ttaggccatc ttcagcatgc tttaacacaa ctgtaaactt tgggttcaaa cttttaaatc
421621 ccccaattgg aagcttggga gatcccgtta aaaattgcaa aaataatctt ctttcatgct
421681 taccaaacgc ggatattatt gatataaaat catgaatgat tgaagaatcc attgtatagc
421741 catgttcagc gttcaagttt gtgtataaag ttgccataga ccagtcttcc tcaactcgtc
421801 cgaaaatatc cactaattca tccggaaaaa gtattagcat cctctcatag gaaaacacct
421861 ttgaaaaacc ttcaataaat gcttttaact gtttttcaat gcccttacct aatatttggt
421921 cgataacgcc atggatatat tcttcaacat tagaagagtt caaggattta ttacaacccc
421981 ccggaatcaa ctcaatgtca tcatttccag gaacggtaaa tgtcaaggac aacgattcta
422041 gggtcatatt gtcatcctta ttcgctacta tgtatttaag ggattttgcg agtaacggat
422101 ctaccaattc gatcattaac agacaggttt caacgtcgct cggcactgtc gtcacattgg
422161 gcgtagacat tctgtgcaat aactcaaaaa agactttgct aaatctaaag tcaagaattc
422221 tattatcaag caacgatctg gcaacaaatg tccccaaata tccaaaaagt tcaataactt
422281 tttcattatt ggaaaacggg ttgaggggct ctgggaacaa taaagtggta atataatcgt
422341 cagtagtatc aacatccatt tcgcttctgt aactataaga gttacaacgc cacatattta
422401 acgactttct tgcaaaatac ttggaaacta cggagtaaaa ttccaaagtc ggtcctaaac
422461 ctgttcctgc ttcttcttga tattcaattt ccagtacgtc agggctactt ccgtacttgg
422521 ataaaatctt gagaccggta gcgaatattg tttttcttga aatccgcagc ttacgcctag
422581 taattctccc aagttgttgt aaagcttcgt cattccttaa atctttcgag cctttactct
422641 tattcttcca aagttgaatc aatcttccgt aaccaaatga agtacattgt aggaaaagca
422701 tcctggtatc aaacggaaac aaaaatggga atctcctggt caaaaatagt gaccaatccg
422761 gcaaagctcc acttgctact accaatggtt catctagttg tctagcgagc ttagcgctta
422821 gttttgagtt gataaaactg tcgcttttaa caccgcagct atgtagaaaa tccagcaatg
422881 tcagaatatc cgctgaagat ccagtatcaa cctgtgcgaa ttctcttttt ttataaaaat
422941 ctcttaactt tttcccctca ttagcttcct cggctgcctc actctctcta ttgttacctt
423001 ctaaactttt gcaaaatttg attgtatgtg tatcatccca taaagttttt aagtcacgat
423061 ttcgcctgac gaatgtatta aatatcacac caaatactgt agactccatg tcaacttttt
423121 cattatcata aaaaaagtca aagttctttt ttctcatatg atccaagcaa ttttcttctt
423181 cttccctatc agcttcggta ctggaagatg taaggtttgg gattaatgaa ttcaaaaaac
423241 gcattcttac cattctgtgt ctcaaaaact cattaagtga ggtaaaagaa gctatgcaat
423301 ggaccgaaac gatagtagat gataaatcag taccaatatt atctttgctt gcatcgccat
423361 cataaaccaa cttaattttt atctctttag ccagtgaaga tacaccacca ccatcgtgta
423421 aaccgcaatc aactatagag aaattctcca gccttgtgag agcagattgt aggatttcta
423481 aaaatctgtc aatacaatcc tcaaatacct ctaaaaatga tttagcaaga atgaaatggg
423541 ataccgttga ggatgtaatt cttttagtta tggaggaagc tagccctgta gaagtaaatt
423601 cgaaacctga cacgtcgaaa tcttcatgga aaatacattt ttttaaaaca gaccaaattc
423661 ccttccaatc ctcttcagtt ttgtccggag tggaaggatt ttctaaaata gaaacaacgc
423721 cttcgatttg atggagctcc tctgttattg cttcttgctc aacgttcatc tgagaaagta
423781 ctctattaac taggttcaca cccttgtttt taatataagc tagagataga gttctgaaaa
423841 tgtgtattga aattttcttt ggttttactg aatcaggaat ttccatatca gtaaattcgt
423901 aatcatattc ttcatcaccc tcatcacatt cctcaatact gctatgcaaa tccccttctt
423961 cgtcagaaag tgaaatattt tcattcccgt cttcctttaa atcaatgtta ttgaaatcca
424021 cagacaaatc cttaaccaaa tcaaaaatgc cctctctttt gatggaagga aagaacagtt
424081 cggaaaactt tttacaaatt aagtcaagca acgagagacc accaaccaac agtgtaccag
424141 cttctgatga gtaagtacca ttagcgttag acgctgtttc tttttgggcc aggatagatc
424201 cgattaactt aataagttga tcattgattg cctttgctgt ggaattattt atgcatgata
424261 caaccctcag taaagcaata agtacgtatc ttcttacgtc aaagtcagca gcatttgtat
424321 aaatttcaac gagaattgga attagacatt gaactaggga atcaaacttt tcctggttag
424381 aaattacgcc acggtcgcta tttccggtat atttatccgc tgacagtatt ctttcatcct
424441 cgggaggaaa caatacaact ataaatctag aaatgctaat caataaactg tttgggacat
424501 aaatcagtgt ttcatgtaac cctgcgttag gacttttact ataatgctgg aatgatcgtg
424561 ttgccatgtc gacaatgtca gttttctctc tcagttctct tgaaagtaca tcactactca
424621 tcgctaatac ggttaaaata tccaaacatt tcagtttatt ctccaagggg gtatcctgaa
424681 tagaaactag ctgaactatt ctttcgatta aatccaacga aaacaaagtc tcaaatttgt
424741 caaccccatg caacgccccg caaataccgt acatggcatt tacaagcctg gttaatattg
424801 gttggtctgt cgcattcgag aaaattggct tcagcgttgg aagtacttca acaatggtct
424861 taaagtcatc cgttcggata ctgctacagg cgttcgaaac aattgcgata gccttcctct
424921 gcgcatgtat agttaaaaaa tcgaagaatt ggacgtagat tgataattgg cccgttttta
424981 aaatgtctct cccatgtact ctagaaatat attccaccgt ttctaaaact tgttctgcga
425041 ggtcaatgta actgatctct accaattttc cttgtaaaat tggtataacg tgttcatcaa
425101 cagctattga aatagattca gggcagacct caaaaagatt atacatgcat ctacaagctt
425161 gcatttgtaa ttctaattct tcccgtaaaa ttttatcaga gagtatggca gctatattac
425221 ctattaaggt ttccatcggt ataattctat cgacaaccat ttgattcatc attaatatgt
425281 tttcagaaag ttcttttaaa ctctccattg caatataagg atcctcggag gcattcccag
425341 tattctctat caatttagaa atccgctcat tccttgccga actctctgcg ctcctctcca
425401 tccttcctcc aatcatcgat aaaatctcgg gtagtgttct tccaaccggg tgttgcccaa
425461 gtccttcact tgtttgtctt ctttgttcta gtctttgtgc gaatgtttcc aaaatgtcag
425521 gtaaatgtag ggggttgctg ccaaattcat tattatcgtg agaacgttca agtccatctt
425581 cttcttcatt tctgtcttcg tcactgccat tctgagttct atgatatcca tataaaagtc
425641 cagaatcatc ttcatgatgg taatcgttat cgtcatcttc accatcatct gcctcaaaac
425701 ttccgacgct agaaagcata tgttcatctt catcttcatc aggataataa gagtactcac
425761 cctgtacatg gccatcctca tcatagtcat cttctacctg cgtatccatc atataatcac
425821 tgttttcgct atgggactca tgttcatcaa ggttgtgcga attattttca gacatgcttg
425881 gctactcttc tattttaaat gtttatccaa aattttcaca cctgagatat attgttgtta
425941 ataaagcaca cagaaaggaa agtatcgatc ccagaaagtg gtctttccct gggtatgatc
426001 aaagctattc ccctttccaa ctactgttgg ctatgatccc acaatttgat ttcagttcag
426061 aaaacccaac cattaggact ttacccggcg aaggtgaaag aaaaaatttt tttccagaaa
426121 aatgcgatga gcttttgaaa agttgcaaat atttgtagta ctttggctaa gcagagctga
426181 ttccttttgc tatacgtaca tcactgtcta tcgtccataa aagatttatt atagttgaat
426241 catgccaaga tcaaaacgtt ccaagctagt cactttagca caaaccgata aaaagggcag
426301 agaaaataaa gaaagaattt tcgatgaagt gagggaagcc ttagatactt atagatacgt
426361 ctgggtccta catcttgacg acgtaagaac tccagtttta caagaaatca gaacatcttg
426421 ggcaggctct aagttaatta tgggtaagag gaaagtttta caaaaagcat tgggagaaaa
426481 gagggaagaa gaatacaaag aaaatctgta tcaattgagt aagctttgta gcggtgtcac
426541 tggtttattg ttcactgatg aggatgtcaa cactgtcaag gaatacttta agtcatacgt
426601 tcgttcagac tattcaagac cgaacacgaa agcaccacta acatttacaa ttcctgaggg
426661 cattgtctac tcacgtggtg gtcaaattcc agctgaggaa gatgttccaa tgattcattc
426721 tttagagcca actatgagaa acaaatttga aattccaact aaaatcaaag ctggtaagat
426781 caccattgac agtccatatt tagtttgcac tgaaggagaa aaattagatg ttcgtcaagc
426841 tttaatactg aaacaattcg gtatcgctgc ttctgaattc aaagtcaagg tgtcggccta
426901 ctatgacaac gatagctcca ctgttgaaag cactaacatc aacatggaat aagctgaact
426961 attatttgga agcctttttt aatagaccat tgtataaaaa tttctttttt ttgtatagat
427021 atactaaagc aacgctcata aatgtaacat agcttctttt caactgagaa tttatattca
427081 tgctaactaa gcgtaaatca cttttgatct tcacagctct ttagcggcac gaaagcaaga
427141 aaaaaagata acactgtatg tctggaaaag aatactataa aaatacctgt ttacataaac
427201 caataaggaa gaacgtgaga gcaggaccgt aaaagaatta atgtgtaaag aattaatgtg
427261 taatggttat actacttaaa aacaccgttt tccttcaaat atcctttttc gttggagtac
427321 tgtcagttgg agtagtggaa ctttcatcac tttcttcgtc tgattcacta tcacttctgt
427381 catccttgag aatacctctc catagaatcc tgtaaagaac tctaaaaata aggaacagcc
427441 aataaagatt cactaattgc aaagcgccta tcaatacaaa gacaattggt aaggaaatcc
427501 aacatttata ttgctgagtg gcaaaattca agacatagtt accttccgtg cgaaattgcg
427561 ttaaaacgga ccataggatc tttaaattta tgtaatgacg caaataaatc cacgcaacaa
427621 caaagatagc aaaagaaaaa aaagccaatc cagagtccaa ataatttaga gttttggaga
427681 atgacaaaag aaaatcagaa acatccattg tgatatagat tggcagtccc attttagtga
427741 aatgaaatac gtaggaagac caaatcaata gtaaagtaac aatatgatgg aaagtcaact
427801 cgttatgatc ttttcttggc ttttctagtt gcaatacaag aatgcaggct tgttgagccc
427861 aaaatgcagc ttgacccaaa tagaatacct tgaataagaa gggattagtg aaatctggat
427921 atgttctgta cattgccttt gtgttgaaaa accataaatc cgaatggtac atacaatata
427981 tcccgaaagg accggaaaca ccggtgtaga aaatagcgta catttgttcc atgattcttt
428041 ttattctgtg cttagaagtg acgtgtaacc taatagcgaa cggtctaatg acaacatcca
428101 ttaggaattc acgtaagaat gtgaaaaaaa tcatatagta aaatacaaag cacaaatcgt
428161 taataccttt accatatgcg ttggtatcac ctatttggta tgacacagcg acaaatctat
428221 gtaacacatt tgtctttgta gtgttaccag aagtgaaata ggcactatat accgcgatta
428281 aaatcatcaa gggagctatc caggcatgac ggtaacttat ctctcggaat gaaaaccaga
428341 ttttcttgac caggtcgcta tcatttttgg tggcttcaga taatctctgc atacgccttt
428401 tagcagccgt tttagattct tttgtctcga acatagtacc taaactaggt acagtgtccc
428461 cgaggtcgat cttacctatg gaagacttgc gtcttggtct tgacctcact ttcaaattgt
428521 tgtttgaagg gcttggcttt attgtcgaca tagctcttgt ttattgatac tgtgtctatc
428581 taaatgttta ccggaggtat gaataataaa aacaatagcg atcaaccgac aaaaatatct
428641 gtatggaaca gaaaaacggt aacgaacaag aaactgtagt tttaacttaa atcaggtccg
428701 gattataaag ccgatgtagc agaaaaacgg gttcacggaa tacaatagcc aaataacaat
428761 aaataaataa ataaataaat aagaaaaaaa aaaagcaagt aaataaaaca aaacgggatg
428821 caacaagcca aggagggaaa caatagaaaa ataacttaaa aatctttgtc tagattccaa
428881 tactttctcc ctcctcccac gttatttgtc tagcatgatc aggtacaatg cccaccgata
428941 tgagaaaaaa gagtgaaaaa aaaaaaatga cgaaaatggt tccgcggatc tagcaacttt
429001 gttggaatga ccggaaaaga cagttgtttc ctttccaact atttttcatt cctggtcttt
429061 ttcctgttga agcccagcat tttttttttc gcgtcgcgtt ttttcacaac agttcggatc
429121 acgtgataat cactgcacgt gactatcatg tgatacgata gccgggttat gatccccttt
429181 ttcttcctat tggaatactg attttacagt ggctagtact ggatttgagt ataggaaggt
429241 gttagcaact gtaaggtact attcagaccg ttaatccaac ggatcataag agcgacagaa
429301 aatgtctagt agtaaattcg aagaggtcat caacaagatc atcaatgaca gccctccagg
429361 agaattaagg gaagtatacg acgatctaat caagatcaca agtgaaaact ccaaaaatac
429421 tattttggat gctattgaga attacaacgt gcagaattgc atccctatag aagtcaacgg
429481 gaactctgta attatttcca aatacaacaa ggaaggagca aagttttttg atcccgtaaa
429541 ttccgtaata ttttcagtta accatttaga gcgcaagggc cttgacattg aaccatatga
429601 gttcacgcat gcaaagatag agaaagggca attgaaagaa ctgcacgata aattgcacga
429661 atatcttctt cagagctttc caggtgatgt cagttttgct gtttacccag tccctgagga
429721 aataagtaaa atttctatta ttattgttag caccaaatat aatccaaaca atttctggaa
429781 cggccattgg agatcaagct acatctacga tttggagacc agggagttat ccggtcaaat
429841 ctctacgcaa gtccactatt acgaagacgg taacgttagt ttccaatctg ggaaggatat
429901 caatcaatct aacgttgatg acgttgtttg cacaataagg gatattgaga cgaatttcga
429961 aaatgatcta gatctttcat ttttcgactt gaacgaaaaa cagtttaagg ccttaagaag
430021 aagattacca gtcacgagat ccaaaattaa ctggggtagt gcgattggca gttatagatt
430081 gggtaagaat gcggcagaag gcaaatgaaa tttcatgcct gccttattcc attctcttcc
430141 tatttcttaa attgaataca tctatgtaca ttatttattt ttggcttgat tggctcacta
430201 aaataactta aacagggtat atagaatgaa gaatattaat aacgccaaac ccaccattct
430261 ccatatgcta ttaccagcct ttaatgatcg ggttaacctt gaggacgaat ttttgatatc
430321 ggtaaacatc gatcccaatg aatctgtcat ttggtttatg acagaactgt cagagaccgc
430381 tcggtctcca atctcttggt ttatgtttct gaatgtagct aatttattgg ctaacccctc
430441 tagtttccta tcattctgtt taaagtacat gtacatgaag ggatgataca tctgctcatc
430501 cggtgtacag aagcaatagt tagtagctta taacatccat atagcaagct aggtcccatt
430561 ctaaacacct atgcgtgttg ccggtgattt acatacgttt gattcggtct gagaatacct
430621 agaatttgac atcgctatga tgattatata ttacctttct accgttctct ccttgttgag
430681 ttcttccagt atccttctta atgatatacc ttatattatt tcctcttttt ttttctgcat
430741 gtagcaatgc gcggcttctt gcaataacaa gaaaactaga gtagctaatt tactgcatga
430801 accgtacatt cagcaacaag aaacataaga tacttaccgc acaatattca ttggtcagtt
430861 accgtacaca cgaagatcct ttctgagtag cgtagtttaa gggagcacac atttttaaat
430921 tctaaacatt gcctcaagat gttctcccat atacaaggaa ggaatattga gcaacatggt
430981 taatctgcca gttgcaacaa cgcaagtgtt attagaaata ttgttcaagg aaaatatcag
431041 ataaaaaatt tttcgcactt cgctaatcac ccatatagaa catggcggtg ttccaagtga
431101 ttagccctag atcgcaaatt atatcatcat tcagttacct ttctcattga atcttcttga
431161 taagaactac tggtacctca aataggaacg aaatatgata ccactgtatc atactatcat
431221 tctcaacaca tttgttatat attttatgtt tctactgaac cttttgtcag tcatctcact
431281 agcagctgcg attaacagtc atcggatatt taaaattgaa gcttttaaaa ttgaagcttt
431341 taaaatcaaa catgaataca cattggagtt cactgaagaa attaggttta aataaaaaaa
431401 tccagcatta gttgtgaagt aaaaaaagac aaaaccagca aattcttgcc agaatgtaac
431461 tatactctga gtaaaataat tgacagcgca aatacaccca tacactattt ttacatcttg
431521 acatcacata cataatatgt gtgaaatatc aaattttgag tgtccgttat caattttttt
431581 tcgattttgc attttatgaa gcttcaaaca ggtgtcggcc taactttccg cccggaaaag
431641 agcggtttac gagagattgc tgcttgcagc tgcgtgcatt tttccataat cgggtttccc
431701 ttcagcgcgc agtgtttcca ttctcagccc aattggcaac ggagagagcg tagagctttc
431761 agtggactgc ccttcgtact cgtcgagtac tattgaactg aaaaaaaagt aatctaaggt
431821 taagttgatc aggtctgccg attgtataac aaatttaatt gtttgtctta gtgaacaaag
431881 agagtcgtga aaaataaaat aaacaatgtc caccgattct attgtcaagg cttctaactg
431941 gagattagtc gaagttggcc gtgtggtttt gatcaagaag ggtcaatccg caggtaaatt
432001 ggccgctatc gtcgaaatta ttgaccaaaa gaaggtatgt taaatccgga aaacctatca
432061 tcgatttgag gagggaaatg aacgaggaat gagatttagg ctacgaaaaa gtgctggcaa
432121 atatccaatc cgttaccatg gatgaagcta cttgtaaacg ataagtaaat gtgaaaatac
432181 acattgcgat agagatacaa aaaagtcttt atttccctgt tggagtggcc tatagtggat
432241 tatttattta ttttgctagc agcttaccta gtttcagaaa ggtgatgacc catatttgcg
432301 cagttaattc ttaaagagcc tgaccatgtt tcctcaaata ttaaaccatg ccttccatcg
432361 ttttgaaaaa atttcgttta ctaacaactt ttatgaataa tttttttaaa ttatttgtta
432421 taattattat aggttttgat tgacggtcca aaagctggtg ttccacgtca agccatcaac
432481 ttgggtcaag ttgtcttaac tccattgacc tttgctctac caagaggtgc tagaactgct
432541 accgtttcta agaagtgggc tgctgctgct gtctgcgaaa agtgggctgc ttcatcttgg
432601 gctaagaaga ttgctcaacg tgaaagacgt gctgctttga ctgactttga aagattccaa
432661 gttatggttt taagaaagca aaagagatac actgtcaaga aggctttggc taaggcttaa
432721 aatatgtaca tgatctttaa ttctgatata tttcgtatgt aattttatct ttaactggtg
432781 attcttttaa taaataaact acaatattat aactattgaa agcctctgtt attcacacat
432841 ctttggaaaa aaaaaaatac aaatacccag tgagtactaa gtaaatttgg agtacctaag
432901 ggcttgtatc ggtggggttc ctgacctagc tttatgtttt acaaacgcat gcatataaaa
432961 tttacaaaac tacaaaaacc atgaacacaa tgaaaagaag gaaaaagagt aggtttgtcg
433021 tgaaagtaca cgcctctgaa gttttgttat catattacta taatattgtt acaactctta
433081 ggaatcttat atttaatgga taaattcctg tttcacgaca acaaatgcga ataatgttct
433141 ttcatctgat ttcattcgcg aaaatctctc agatctttca tcattgtgac tgcctaaaat
433201 atctttcaaa atttcaggaa tttcaccgcc cttcgatgga acgatataaa aatccttctc
433261 gtatctagtt tttggcttta tacctgcaat gcgacctttg ttttccaggg agtctacaac
433321 gtcggcaaaa gttgtcttac tttcactatc attcgaagga aataattggt atactaatat
433381 agctctagag caagaaattt ccttaagata tggtgcagca gtggttgtag gtaagcgccc
433441 ttctacatac agttttccgt caccaatggc ttccttgaaa atatcccgtc ttaacttttg
433501 tgaagcccca atgtagttta ggtaacctgt aaactcaagt cctaagccgg gatacaaaaa
433561 tgcgcagttt aaagattctt cgttgattat tgtacttggg ctgggttctt tcgaaatggc
433621 atgagtctgt tctattttac tcttatcgct gtcgatactg tcaatgttgt gtaatcttat
433681 gctgtctttt gagtacaaaa tatcctcttg aggttcagcg atatcttcga tcagctcatc
433741 acccttgtgg gtcttaacgt acatgggttt gtcaggtacc tccacgataa aattttctaa
433801 gataatctta tcccttttct ctttaaattc ttgtaagtca ggatttgcga gttcagatgc
433861 gttcatgttc accagtttat ttaaaggcaa tttgccctcg acaacgtgtg ccttcagttc
433921 caaatttttt ttatccttta aattagagta taacgacctc actttctctg tgtatatctt
433981 gtccaaagta ccaaactcga cgttaaggca agctttgtaa agttcttctt ccagattgtg
434041 cgcaaactct tgcgatatcg atataacgtc tttcccatca ggaagctcat aaagttttgc
434101 ctcaattgtt tcgggaacga tgaatttgct aaataaggta gagaacattt tttctgcatt
434161 atacctcagt ttgtgttctt tttcgctttc aaaatctttc ctagtaggca tttcgttttc
434221 ggcagtatca gacttggcgg catcaatgct tttattcctt ttttttgacc cattggattt
434281 cttcacctgt ttggatttga tatgaattcc tttggcacta tcggggctcc tttttcgttt
434341 cctagggctt tcctcatcaa gaaagacatc tgcatcattg tcatcatggt catttacggg
434401 cttgtaaaca tcatcatggt aatcttcatc ctctgaaacc tctgcctcct ttgacgtttc
434461 caaatgtgca tacaatgatg ggtcgcacaa ttcacagtag tacttagaat cttcactcat
434521 tagcccatct atggtgtctt taccatcagt catacattta atatgctgcc aagtgtcaca
434581 gccatcgcac tgtaccatgt cgccatgcga atattctgca gcatcgtagt tttcattgtt
434641 cgccccacac agacatctaa catagccctc atccgcttcg tctacttcgt ctgttcttac
434701 attttcagta tctttccttg gctcctgaga agaatcagac ttcttattct tctctatggc
434761 tgaatcaact ttctttttag ttcttttttt ctttggtgct tcagtctcct cctgtaacaa
434821 atactcaata tatttattct gacccttatt agatcttgaa gaagtacgga cagacataat
434881 aaatttaaac taaataaaag ctaaaagtaa aagagaacct aggataatcg atagctccct
434941 gtgtatagaa caagtcaaaa tactaagatc tcgtcaacct atcctctttc attgcaagcc
435001 ttttggccaa actgcagtct gggcatccct ttgcatgtct tgtgaaatag tatccatctc
435061 tccccagctc ccagaaatga tatgaaaagt tattcgtgaa gagtgatcct aaaactgaaa
435121 aaaggaaaaa acaaaaatga gctaaaaaaa ccacaacaaa agaatatcaa cttcattgct
435181 tggcgggtca tcgctttttt atttctttct gtcaaagaat aataaagtgc ccatcagtgt
435241 tcatatttgt tacaaagtgg ttttctgatt tggtactact gcagaggcgt attttttgct
435301 tcagttacca tagcgtaaga acactagcga cttttgttcg tgaaccaaca gagtaggatt
435361 tctactgcta catctcttag gtagttggtt agtccgatcg ctcacttttg gttgttgtta
435421 agtacttcat aagtttatcc ttttcctttt tcacactgag ctactttggg tatagctttt
435481 ggcccaagga tctttgaatt ttctccaaaa gtactttatt ttatatccta caggttgcgg
435541 ttttcatatt ttaaaaagct tttaatcatt cctttgcgta tggcaaaccc tttttcgaga
435601 tggtttctat cagagagacc tccaaactgc catgtagccg atttagaaac aagtttagat
435661 ccccatcaaa cgttgttgaa ggtgcaaaaa tacaaacccg ctttaagcga ctgggtgcat
435721 tacatcttct tgggatccat catgctgttt gtgttcatta ctaatcccgc accttggatc
435781 ttcaagatcc ttttttattg tttcttgggc actttattca tcattccagc tacgtcacag
435841 tttttcttca atgccttgcc catcctaaca tgggtggcgc tgtatttcac ttcatcgtac
435901 tttccagatg accgcaggcc tcctattact gtcaaagtgt taccagcggt ggaaacaatt
435961 ttatacggcg acaatttaag tgatattctt gcaacatcga cgaattcctt tttggacatt
436021 ttagcatggt taccgtacgg actatttcat tttggggccc catttgtcgt tgctgccatc
436081 ttattcgtat ttggtccacc aactgttttg caaggttatg cttttgcatt tggttatatg
436141 aacctgtttg gtgttatcat gcaaaatgtc tttccagccg ctcccccatg gtataaaatt
436201 ctctatggat tgcaatcagc caactatgat atgcatggct cgcctggtgg attagctaga
436261 attgataagc tactcggtat taatatgtat actacagctt tttcaaattc ctccgtcatt
436321 ttcggtgctt ttccttcact gcattccggg tgtgctacta tggaagccct gtttttctgt
436381 tattgttttc caaaattgaa gcccttgttt attgcttatg tttgctggtt atggtggtca
436441 actatgtatc tgacacacca ttattttgta gaccttatgg caggttctgt gctgtcatac
436501 gttattttcc agtacacaaa gtacacacat ttaccaattg tagatacatc tcttttttgc
436561 agatggtcat acacttcaat tgagaaatac gatatatcaa agagtgatcc attggctgca
436621 gattcaaacg atatcgaaag tgtccctttg tccaacttgg aacttgactt tgatcttaat
436681 atgactgatg aacccagtgt aagcccttcg ttatttgatg gatctacttc tgtttctcgt
436741 tcgtccgcca cgtctataac gtcactaggt gtaaagaggg cttaatgagt attttatctg
436801 caattacgga tacggttggt cttatgtaga tacatataaa tatatatctt tttctttctt
436861 tttcttagtc aggattgtcg tttagcataa tatacatgta gtttatttaa tcacatacca
436921 ctgattatct ttagaatttt ataaattttt gaaataaatg ggtggctttt aatggtgtct
436981 atgttaagtg aggcttttag aatgctcttc ctgctttgtt tattatatgt gtatgaaaga
437041 tatgtatgta tttacatgtg tttgtagcgt ccccagtcaa aacctgtgcg ctatacctaa
437101 atggattgat aatcttcatt cactaattct aaaatagact tcttccccaa agaacggtgt
437161 aacgatgagg ctctatccag ctgcttatct aaatcaactt taacgatgga tgatcttatg
437221 acacggggat ctttctttaa agttcttaga atttcagact gtaccgcagc tgatgaatca
437281 aacagcatta aaaagtgata tgctcgaaaa tgtttttcct ggtctttctt cattatttta
437341 ggaagatacc ttatgcccat gggtacaatg tccctcacca cacctctgtt ttgaataatc
437401 agtttcccga ttgtggaaga caattctttt gcttccaact ttggcgcatt ggagttggtt
437461 atgcgaacaa gtccgatcag ctcataaagc atcttagtga aaagggtggt tttgcgttat
437521 tctttcctct gttgaagctt ttctattttg tttaagctga actagtggga gtttccatta
437581 aaaggctaaa gtcttgttga aacttttccg ggttagatga taactgcgaa aagatagata
437641 aaatcagcat taaagggact tcgtctcctc ctaatcagaa atcatccttt cgaattatgc
437701 gtattcagtt gaagcgtatt tgtgaccagt gtacttcaag gctgattgtt tcacccttgg
437761 acacagaacg ttaaacaatg agtttgtttg agtgggtatt tggaaagaat gtcactccgc
437821 aagagaggtt aaaaaaagta tgttgttctg tatttggatc agttatttta gtgaacatac
437881 taacgttaat tatttgagtt tttagaatca aagggcttta gaaaggactc agagggagct
437941 tgaaagagaa aagagaaaat tggaactaca agataaaaaa cttgtatcag aaattaaaaa
438001 atcggcaaag aatgggcaag ttgcagctgc gaaagttcaa gcaaaagatt tagtaagaac
438061 ccggaattac atccaaaaat ttgacaacat gaaagctcaa cttcaggcga tatcattgag
438121 aatacaggcc gttcgaagta gtgaccaaat gacacgttct atgagcgagg ccactggtct
438181 tttggctgga atgaacagaa caatgaatct acctcagttg caaaggatat cgatggagtt
438241 tgaaaagcag agtgatttga tgggtcaacg acaggaattc atggacgaag ctattgataa
438301 cgtcatgggt gatgaggtgg atgaagacga agaagctgac gaaattgtaa ataaagttct
438361 tgatgagatt ggagtggatt tgaattcaca gttgcaaagc acgcctcaaa atctggtttc
438421 taatgcgccg atcgcagaaa cagcgatggg gattcctgaa cctattggcg ccggatcaga
438481 atttcacggt aatcctgacg atgacttgca agctcggttg aacactttga agaagcagac
438541 ttgagcgctc tgagtatatt taatgaataa taggtctata ctataataca tcaactactg
438601 atatcaaagt aggcacttag aatcaaaagg cttccgaaaa tttgttcagt ttttcacttt
438661 actcaatctc gtcactaaag ttttcttttt ttttcgaatg aatcctcgaa taaatatgtt
438721 ctatattata tatatacatc ttttatatat cattaaatgt acagtaatcg gtcaaattac
438781 aaatgcttac ggatgatttt ttcactgatt aagtactcat aaataatggt agcacattct
438841 tcaaccgtct tctggtcggt tctcaaatgt agctctggag cttttggcgc ttcatatggg
438901 gcagaaatac ctgtaaactc cttgattaca ccctccctag ctttcttgta taaaccctta
438961 gggtcccttt gctcagcgac ttctaatgga acatcaacaa atatttcaat gaacttcaaa
439021 ccagcctcct tatgtagttc acgagctcta tctctgtcaa ctctgtatgg agagataaat
439081 gaggtgattg aaatagcaca tgaatcagca aatagcttag aaacttcgct aattctacga
439141 atgttttcat ttctgtcctt ttctgagaaa cccaaatcct tgttcaatcc aaaacgaatg
439201 ttgtcaccat ccaatctata tgcagacaag tttttttgga gcagtaactg ttctagcgca
439261 caggcgattg tacttttacc tgacgcactt agacctgtta accaaatagt acaaccgtcc
439321 tgttttctca atgccttgcg ttcgtcgtaa gtaagatttg gatgccaagt aatattagta
439381 gccattggtg tacagtgtgc ttggagaaat aattccaact tttcttgatg tcaagttcga
439441 acaaagagag aaaatgaacg acattaacgg atacgcaact gatgttgtat agaaattttg
439501 catcttatat agatattttg acaaattcat gaagttgaag tcatattgag tcgttcatcc
439561 tcttctccat tgccacattt tttgaggtgg cttgtaaata tattgatcac gtgaaattag
439621 tggcacggtc ttttattcct ggaaaagcgt gcagctattt ttcgagaata atgtaaggta
439681 ccgtgggtgc cgtaccatca cgccgaaatg aaagcaactg tattctttaa tgttacgcat
439741 tcttggttgt tggcttattt acatttctcg cgagctggtg atgagccaaa tgtcgtagtg
439801 gaatgattct agaagtgcag agttatctgc tacattgcca aggcgtcgta accgggaggg
439861 ctcacaaagg cgcttgctct aaacatgcat agggaaattt gaaaatgatt gttatgagta
439921 aacctgttaa tgctccttta aacgtaatct tatttcacca attttaaaaa aagaaattgg
439981 taattaacct cacctaactt ctgtaatcac ttgtcaacgc tatttacaat tttgctttga
440041 tttatacaga ggaagcagtt tactctcctt tctatgtgta tttgattatt ttaattacca
440101 agaaaacaaa ttctcgtaac attcttattt tatacgttcg gaaatcatga acatttattt
440161 ttatgattat gtaattaaaa aaatataata aatttatttt gaaaattaat ttttttaaaa
440221 ttttaaatat gtttttatca tgtgacttat gaaaatgata tttacggttc aagagaaaga
440281 taaatgcaga atcaatcaat acaatgaata gtaccttatt tagtattgga ccattgaggt
440341 attaggtatt agtagaaata tcctaaacac tagtattgac aaaagaataa tattatatgc
440401 tatcaattat cattcccatc ctcatgttga ccttcttcat attggacaaa agatactagg
440461 atcgtaatgc gagataggaa attcttcaaa agcataattt atagactagc ttccacgtat
440521 acaagaacaa tatataagat ttgcagtaaa tattagggag aaatactcaa aaccaagctt
440581 gagtcgaccg gtatagatga ggaaaaccta aacagaggag acgatttgac tagcgtttct
440641 caatatctcg accatcttct tacattcttt tcttctttga atggttatgt cgttttcttt
440701 cgttaattct tcaatatctt gctttccgta aagtttttcg agtaaaactt tctgaatatc
440761 agttttactt ttcacaatca atttaagcat caaagccttt ggtataatat cggcaatggt
440821 tcttttgaca atagagaaat aactactaat caacaacttg attacttctg tttccattgt
440881 ttccctctct gtcatttggc cagtagcttt taaaacagga ggtggggatt ccaaagctgc
440941 caatttcttc ttgtttttag tggagaagaa cccaccaaaa aatcctgatt tctcttccat
441001 aactggcgcc ttactagacg atggttgggt tggtaatggt ttacccgtct ttgggtcaac
441061 agcgacttgg cgaggatgta atttttcttc caccataacc attgcttgag aacccttcaa
441121 aaggtcggga tgggctgtat tgatgtaagt ttgttcagct ttgatgatat cgacaacaaa
441181 ctcattcgta ggaatagtag catcctttaa gaactgaatg aactgattag aaatcgcttc
441241 tcttagagca ggataccttg agtactttgg ttgtgaaata atctgtttta gcatacgaac
441301 aagttcatca aacaccagag taactaaacg tagagatggt tcttcaaatc ttctaatttg
441361 ctgtttaact aaaacttcaa aagcttcggt accgacaaac aaagatgggg cagaacctga
441421 actattgtac ataatggttc tgatatcaga atctttgatc tggtcgaatg gatccaaaga
441481 gtctacacca tttttgaaag tttcatggaa tacgtaagaa attctagcac caccagaaag
441541 ttcctgactg gaaagctcct tcgcctcacc gtccaagata ccggcatatt cattggaaaa
441601 atcagtaatc atgctcaaaa caaccgaact agctgaatcc atagtttctg ggcccaagtt
441661 tataagttcg ttttgatatt ttttcaatgt ggcttcgatt ttcgctttga tttctggcag
441721 agtttgccta atgtggtgta ataagattga gtttaacttt ttagccaaat atggtgtacc
441781 acagtaatga gctttagaac tgtaagaggg atggttctca aaaaattttc tttcgttttc
441841 aagggcttct ctgattgttt ttttgtgttc aatatccttt tgacctctat tgataactgg
441901 gatataacca tatctcaaag gaatgactct tccagccaaa atatctatga catctgtacc
441961 ttgatccatc aaatcgactt ttgtcaagac accaatagtt ctcgttcctt ctggatcgac
442021 ctctctagcc agcttcaaac catcgctgtt ggctaaatcg gtgttagcgg cattaacaga
442081 taatatgata gcgtttggtt tcgaaatata ctttaacaac atgtccttaa tttgtctttc
442141 aatatcagga ggttggtcac ctacgggaac cttcgtcaac ccaggcaaat ccactaacgt
442201 caaagtaaga acatgcggag aataaattct caagttaatg ggcacagaag aaatacctga
442261 attggcacct gtcactttgt cagtttcttt gacgatttcc tttctaattt cgtcaaaatt
442321 ataaaacttc ttaccaggta aatgcaaaaa ttcaccccat tcctctttat tgtcttcaga
442381 ttgtccctcg ttctggtgct ttcctgattc atcctttttc ttgtcatcat cgttgatgtt
442441 caagtcaatc aattcattag cagtttggtt tactttagca tgttctgact tttttggtct
442501 cctattaatc aattgtaaca ctaaaggtct cctggtgaca ataccagtac ctcttggcaa
442561 gaaatcccta ccaacaatgt tctccaaaac ggacgacttt cctgacgact gggaaccgac
442621 aacagtgatc tgtggtaaat caataggaga ttgagatcct cctcctaagg gcgccaaagc
442681 gtcctgaagc ttgttaatag tagaaattaa atgctcatcc atgatatctg ataatataaa
442741 atgtgcagtt ttcgtacggt ccttattttg gtgctataaa aggcctctct aattcttttt
442801 taggagtaaa tagatgaatt atctcggtct gtcttggaag atatgttgtt ctcttgatgg
442861 caaagcgacg cgaatcaacg gcgcccaagt ctttgggtga cccggccact taataatgtt
442921 tggggaagaa atcaatccat tagaacattg gttttggaaa ctaggccagt ccaagcgcac
442981 aagtggttta ccctcgagca tttttcgact attagaggat tcaagtatct atcgaattct
443041 ctgaagctat catactatcc tctggacgat attagaacga tttttcaagt gaaacgtttt
443101 agcaaaagtt taaagacact aaactagcta aataatttca ctgtgagcaa gtctttaaac
443161 ggtctttttt gaatcaaaag aggcctagaa ttagcaaaat atttaacgca taaacttttt
443221 ttagacaaat aatgagctct caaaaggttt ttggtattac tggacctgtt tccaccgtgg
443281 gcgccacagc agcagaaaat aaattaaatg atagtttaat ccaagaactg aaaaaggaag
443341 gatcgttcga aacagagcaa gaaactgcca atagggtaca agtgttgaaa atattgcagg
443401 aattggcaca aagatttgtt tatgaagtat cgaagaagaa aaatatgtca gacgggatgg
443461 caagggatgc tggtgggaag atttttacgt atgggtccta tagactagga gtccatgggc
443521 ctggtagtga tatcgatact ttggtagttg ttccaaaaca tgtaactcgg gaagattttt
443581 ttacggtatt tgattcacta ctgagagaga ggaaggaact ggatgaaatt gcacctgtac
443641 ctgatgcgtt tgtcccgatt atcaagataa agttcagtgg tatttctatc gatttaatct
443701 gtgcacgtct agaccaacct caagtgcctt tatccttgac tttatcagat aaaaatctac
443761 tgcgaaatct agacgagaag gacttgagag ctttgaatgg taccagagta acagatgaga
443821 tattagaact ggtaccaaag ccgaatgttt tcagaatcgc tttaagagct attaagctat
443881 gggcccaaag aagggctgtt tatgctaata tttttggttt tcctggtggt gtggcttggg
443941 ccatgctagt ggctagaatt tgtcaactat accctaacgc ctgtagcgca gttatattga
444001 acagattttt catcattttg tcggaatgga attggccaca acctgttatc ttgaaaccaa
444061 ttgaggatgg cccgttacaa gttcgtgtat ggaatccaaa gatatatgcc caagacaggt
444121 ctcatagaat gcccgtcatt acaccagctt atccatcaat gtgtgctacc cataacatca
444181 cggaatctac taaaaaagtc attttacagg aattcgtaag aggcgttcaa attacgaatg
444241 atattttttc caataagaag tcctgggcca atttattcga aaaaaacgat tttttctttc
444301 gatacaagtt ctatttagaa attactgcat atacaagggg cagtgacgag cagcatttaa
444361 aatggagtgg tcttgttgaa agtaaggtaa ggcttctagt tatgaaactg gaggtgttag
444421 ctggaataaa aattgcacat cctttcacca aaccctttga aagtagttat tgttgtccaa
444481 ccgaggatga ctatgaaatg attcaagaca aatacggtag tcataaaact gagacagcac
444541 tgaacgccct taaactggta acagatgaaa ataaagagga agaaagtatt aaagatgcac
444601 caaaggcata tttaagcacc atgtacatag gccttgactt taatattgaa aacaaaaagg
444661 aaaaagttga cattcacatt ccctgcactg aatttgtgaa tttatgtcga agtttcaatg
444721 aggattatgg tgaccacaaa gtattcaatc tagccctccg cttcgtaaag ggttacgatt
444781 tgccagatga agttttcgat gaaaatgaaa agagaccatc aaagaagagt aaaaggaaga
444841 atttagatgc tagacatgaa accgtgaaga gatctaaatc agatgctgct tcaggtgaca
444901 acatcaatgg cacaaccgca gctgttgacg taaactaaga cattcctatt tatagttgaa
444961 tagtttatta atataggtta atcagtcata aacaaatttg tacccttttt tttgaatcaa
445021 agtacttttt ttacgaagca gtaaaacgtt tacgagattc tctctacata tgctctttcg
445081 cgtgtagcga cattttacca ttaggtgaga attttgtgtt acaagctgga tgtcaggatg
445141 atacctttga aggcatagtt aaattggctg ggaaaggaac ggaacctttt cctttccgag
445201 tttcggccag atatttaggc tttttttttt ctgacggaat aggggaccca ggattgacaa
445261 atataacaaa acaagcttca acgagacgtt tatctcgaga attacgtctg acagttacat
445321 gaagtgtgag ttcatgcaat ctgtaccttt attgacacag atatactaaa agaagttaca
445381 atgggctcca aaaaactgac cgtaggatct gattcgcacc ggttgagcaa atccagtttt
445441 tcaagtaata agtcgtcaca ttcagcaaca aaagatcagc caattgatac cgacgatatt
445501 gatgaagacg atgaatctgg tcataatatt atcttgaaca tcatctcaca attgagacca
445561 ggctgcgatt tgaccaggat caccttgcct acttttattt tagaaaaaaa atcgatgctt
445621 gaacgtgtca caaatcagtt acaattccct gagtttttgt tacaggcgca ttcagaaaag
445681 gaccccttga aaagattttt gtacgtaatg aaatggtatt tggcaggctg gcatattgct
445741 ccaaaggctg taaaaaaacc attgaaccca gtccttggtg aatattttac agcttattgg
445801 gatctaccaa acaagcagca ggcatattat atatctgaac agacaagtca ccatcctcca
445861 gaatgtgcat atttttacat gattcctgaa tcttcgatta gagtggatgg ggtcgttatt
445921 cctaaatcta gatttttagg taattcaagt gcggccatga tggatggatc aacagtcttg
445981 caatttctgg acataaagga tggaaacgga aagcccgaaa agtatgttct tacacaacca
446041 aatgtatatg taagaggaat tctttttgga aaaatgagaa tcgaacttgg agatcatatg
446101 ataattaaat ctcctaactt ccaagctgat atagagttca agacaaaggg atatgttttt
446161 ggaacttacg atgcaatcga agggactgta aaggattatg atggcaatgc gtattacgaa
446221 atatctggta aatggaatga cgttatgtat ttaaaggact taaagcaacc tcgttcttca
446281 ccaaaagttt tccttgatac tcataaagag tcaccattga gaccaaaagt tcggccattg
446341 agcgagcaag gtgaatatga atccagaaaa ctgtggaaaa aggttacaga tgcgttggcc
446401 gttcgcaatc atcctgttgc gacagaagaa aaatttcaga ttgaagatca ccaaagacag
446461 ttagccaaaa aacgcattga agatggcgta gaatttcatc caaagttgtt tagaagatca
446521 aagcctggcg aagatcttga ctattgtatt tataaaaata tccctgtcga cgaggaccct
446581 gagaagcaaa tacgaagcat attgcaaata gcacctattt tacctggtca acaatttacc
446641 gacaaatttt tcatccccgc atttgagaaa ataaaatcac aaaagaagat gattgaaaac
446701 gaaaagcaga acccagcaaa acaatagtgt atatgttgga tatgatattt gttgtaaatt
446761 atagattagt ttttttatat gtttttcttt tttttgttct aactatctga ttgttctttc
446821 ttatttttat ccaaaaactt atttaagaaa agctttttat agccaaaatg tgcaaaattc
446881 acagaagtta gaagatcgtt tgaaaatttc tcaggtacta ttggagtatt atttatcatt
446941 ttgatatgac cactgttctc ttcaaaattc agaatttcat ttctccaagt caataagaca
447001 gagtccattt caattctaag ggtgatatta aatttcgtaa tttgcagaag acacagatat
447061 ggaggccaat ctgcagcata cgttcgatca atccatttta ctaattcctg agtaaatgca
447121 tccgcaggct gtacttgaaa attcaaatcc actttattta tcttgaacgg aacattaaaa
447181 gagcttgtta gtctttgaaa atcacgtata ttatcggttt ttttttcctc ctgctggcat
447241 accatatatg ctaatgcgct ccatgaggaa caatccttaa cattttgaaa gcaaaatctc
447301 ttagtcaaat tgaagagctc aattctttta ttgtaaggta aattatcgta gaaccaccta
447361 gcagtattcc aacagtagta attagagaaa tgttgggatc cagaagaatg aaatacaaat
447421 aaaatatctg gaagaaccag tgtattagca tcaagagata aaacgaatag ttttcggtat
447481 aatatccaaa gagatgacga cttgttgata cgattgtttg atgaacaaag aagccgttga
447541 atcagtctta cttctttgac caataaatcc ggtattacta aaacactgtt gtcctggaag
447601 tatctcttga gtaaatcttc gtgtacatta tataccgttt tgttttcagg tgttgtaagt
447661 agaaatccaa cagtcatgta ataaatattc tcattagaaa tgccgcctaa tttacatcaa
447721 tatgtagaat tgttagtagc cgtaacaatg aatccaaaat gcgtattgta aaatagcaat
447781 agttttttgt attttaccgt tgagacatac tttgatcaga gaaagttttg ttaaaatatg
447841 tatgtgcttc ttggaaaaga gataaaaatg ttgttttgaa gataattagt tctatggaat
447901 gggctttttc gtctacgtag taagggagag taattgaagg ctgattggca gtaatggtta
447961 acctgaaatc atgataatct aaatatgcag ttattttttc aaaaaattct ctgcaaaggg
448021 gaagagaaga ttgcataact tcaacaattg ttttgagcgt ttccttttag catttttttg
448081 tttggctttt gtttgttctt ttgtgtactt ttcatgtatt tgatcttcca tgtgcaaaaa
448141 taagtgaaaa agagctgaac taaatgtagt attaaaatca agaacaaaac ataaaaagga
448201 aaggagaaaa tggaacaatt gcttagtcaa ataatgtgaa gttataaaac tgccggaagc
448261 ctataaaaaa tattttcttt actgagaccg tgatcaggag aacgaatgtg tattaatagc
448321 tgtatatatc ttataaagac gaagcctatt tactatcaac gctatgtaag tttgtactat
448381 tatccttgtg aaacaaataa ttggaggaca gtcaatagca tcatctaaca tcgtgaaacg
448441 aatcagtgat tgaaaggaat taaatgagca acgtgcataa ataatatcgg taaagaaaaa
448501 agagcgcaat ggtttcatga ctattctaca ccaagttgtt gcgccatttt atctaagctg
448561 atcccctttt ctggtatgct tacaggaaga gaatagaaat actcttcgtc aaattcaact
448621 tcgtcatctg accaatcgtt atcatcatct gagtcatcga tactatgatc tctaaaagat
448681 acccgcgacc ggtaagaaaa ccccaacatc atcaatgtag taattgatac tgtgatggca
448741 gtgaatatga aaatcctttt gtctaattga gatgccgccg atatgaattc accagaatct
448801 agttctggta agtgcggcac ttgcgaaaag gttgtagaga acagtgtggc ctgctcatta
448861 gcagcgcctg gatcagaaat cttatctctt cttactactg ttggtgtacc tccttcatct
448921 ggtgaagcga gctcaccatt agcgctaaag agaccaaaat ttattcccgc ttttttattc
448981 aatccatccg gattaagtac tgctactaac gacttcgttg cgatagcatt tgttgtcgta
449041 gtagtcgtga tactcaaaaa cgtcgaagtt gcggtacttg ttacgatttt agttcttgga
449101 aaccatcttc ttttggcttt tgtcgacgtg attaaagtcg tccctgtttc agtatcagtc
449161 ttggtcctgt aaaacctgtt cactgtggtt attattttag gactttggta ttcattcact
449221 aagtaacgag taaaaatttt ctttggcctc caagaactcc accttgtcat atgaatttcg
449281 gtggcagtgt gaaataatgg ggccttcgta tttcgttctt ttttactgcc acttttatca
449341 tcggtatcct tactacagtt ttcagaacta actttcttgt tctcatggta ttcgatttta
449401 ccttcccact tcttatcttt cacactacag tcaccgtcgt tttcttcttc ataaccagta
449461 gctggagaca gagttttacc acttatcgtt ctttcgcgca aatattgaac ttcattatta
449521 gcgtcaacca cttcgaacat gtcaactgat gatatagtct tttgattatt ggttaaagag
449581 gttaatagtg cagaaattaa ttggtttttt tcgaactgca aagggttcct aaaaagagta
449641 ttgttttgac caacgaaata agacaatttt ctactagaaa atttgttgcc tctaggtttc
449701 aaaatctctc cgtcatctaa aactccattt gtcaattgaa attgttcaac aacgatctgc
449761 aacttgtcat actcatcttt ggaggtacag taatcgtgaa agcagctatt attaagggaa
449821 ctcaaggcac actgtaaaca tttgcagtta tccaagtcct ccattgtttc attattcaca
449881 gtaacgcatg accgacaaaa tgcatattgt tcatcaaaat aacgggacac gcattcactt
449941 aaatttcgtt tcttcacatg gatcttgtca gtaataaaat ctagagaata ttagtacctc
450001 ggtaaatttg ttgtacatac gcaactggag aggaaggggg aaatcagttg tgaattgtaa
450061 cctggacata agttaggatc tgccacagtt ttgctttgaa ccgctgcgag aacgctccca
450121 ccaccaccgg caaagagaac cagcagagcg cttagacatt ccaacattat cagtatatct
450181 cgtgtgttcc tgcctcttga tgattttagc tagctgtaat gtgtaacgaa ttattccctt
450241 actgcttctt gagttagccg ccaaagagga aatatagcca caaaaagaac ttacagaaaa
450301 gataaggtaa aaaaaaaaag tgatctataa tgggaaagaa aaatccaaac ttcttcaaag
450361 agtatatata tgtacaggat attaaaatgt aatgatagta gtaataatag tattaacata
450421 agctaagcgg atcttgctgt ttccaaagct tttcttgttg catcatcctc taacttttga
450481 atttctttca taatagtatc atatttactt ttttgctctt tagaagtaac atcgttaaca
450541 acatatatgt ttggtgacgc gtaattatca gaaaatgggt ggatagcatt tggctcagct
450601 tctttataag cgagtttagg atcgttggca gatggcaaaa ttttttcctt aatatacctt
450661 ttaaactgca agggtgtgct taaagtggtc agttcataat caggaattag atagccagat
450721 ttagattgca aaaatttggt gaactgaaat ttagctacca aatcagagaa ttggacgtcc
450781 tggtctactt tgcccaatgt tttttccgtt gcctgcaata tcatatcatc taactgatta
450841 tcagacgtaa tcttatccct ggataaccac tgattgaatg gcgcagagga gaccgcaagc
450901 ttcaactcct tctgtctctt acaccgtcta gacccttcgc caataaaatt ttctggtatt
450961 agctccaatc tgtttttgtt attggaagag gattgagagg aagcctcgtt agtgccttct
451021 tcaatatcct ttatcaactg tttggtgtcc ttgacaggct cttggtgctc ttcttgcttc
451081 ttcctcttga accatgacat aaagtccccg tttgcagcgg aactgtgaat acatctggct
451141 ttctgcttgt agccagagag ccagaccgac ctttgcggca atggtctaat acaatgtaat
451201 ttaagcagtg acgacatcct catactatgt ccgcctttcc gtctacccat tattcacttc
451261 aggactgatg atcaggcatg cagttaattt gacagaagtc gttgtttcac tataaatttg
451321 tcagctaccc gcctcaccag cagcgataaa gaacgaagaa taaaagagag cattcacaga
451381 gtacgaatcc agtatagcgg tagtggatac aacgacagat ttaagtcgta aaaatgggag
451441 ccgtactcag ctgttgtaga aaccattccg gcgaagagaa tgaagctttg ctgagggaac
451501 agcaggcagg ctatggaagt caaggaaacg caaatgacga atacgatgcc gaacaaatgc
451561 ggttgaagga acacgaacac gaacagaaac tgctggccag ggaacaagag ttaagagaca
451621 ttgttgcaaa caccaacgat aaactaatag acatatcgat gataaacaat agtggcattg
451681 taattcaagg gacagacctg caagaagctc ttgataaaag acaacaggaa gaaggtggag
451741 attcccggga agacgaaagg agtgcaggtg atgacaacct cagtgggcac tcagtgcctt
451801 caagcggatc cgcacaggca actactcacc aaactgcacc aaggactaat acgtttactc
451861 tgcttacatc accggattca gcgaaaatat caaaggaaca gttaaagaag ttgcactcta
451921 atatactaaa tgaaattttc agccagtccc aggtaaacaa accaggcccc ttgacggttc
451981 ccttttaatg aactttttgt ataacatcat tggtatacaa gctttataaa taaatgttaa
452041 atagttaatg aaataaaaaa tcacatttga cgaattcgga agacaagtag cccaagaaaa
452101 aaaacaacaa aagcatgcta gaggatgatg tttaaaacga ccctcagcct gttattacaa
452161 tagagagcaa accaaagaat aatagataaa gtacacagat atggtagtta agaagcgtaa
452221 gttggcaact gaggccggtg gcagtgatga aaggcctaaa tacttgccgg gaaaacatcc
452281 taaaaaccaa gagaaaactc cgcatgtgga ttataacgcc ccattaaacc ctaaatctga
452341 actttttcta gatgactggc atatacctaa atttaatcga tttattagtt tcactttgga
452401 tgttcttatc gacaaataca aagatatttt caaagatttc atcaaactac caagtaggaa
452461 gtttcatcca cagtattatt acaagatcca gcagccaatg tctattaatg aaatcaagtc
452521 aagagattat gaatacgaag atggtccaag taattttctt ttggatgttg agctactgac
452581 aaagaattgt caagcttaca atgaatatga cagtttgatt gtaaaaaact ccatgcaagt
452641 agtaatgttg attgaatttg aagtattgaa ggcaaaaaat ttgaaaagaa attacttaat
452701 taacagcgag gtcaaagcca aattactgca ctatcttaat aagctagttg acgccacgga
452761 aaagaaaatc aaccaggctc tgctgggtgc gtcatctcct aaaaacttag acgacaaagt
452821 caagctaagt gaaccgttta tggaattagt cgataaagat gaacttcctg aatattatga
452881 aatagtgcat agccccatgg ctttatcgat cgtaaagcag aacctcgaaa ttggtcagta
452941 ttccaagata tatgatttca tcattgatat gcttttagtt tttcagaatg ctcatatatt
453001 caatgatcca agcgctttga tttacaaaga cgcaacaact ttaacaaatt attttaacta
453061 cttaatacaa aaggaattct tcccagagtt acaggattta aatgaacgtg gcgaaattaa
453121 tttagaattt gacaaattcg aattcgaaaa ctacttagct attggtggtg gtggtccagc
453181 cgcagcaggt gcgttagcta tatctgctct tgataatgat attgagccag aatctaaccg
453241 tgaagatctt attgatcaag cagattatga tttcaatcat ttcgaaggtc tcggcaatgg
453301 ttataatcgt tctctcctaa ctgaagatta tttactgaac ccaaacaact tcaaaaagtt
453361 aatagccaaa ccggaaacag tgcaatccga agtcaaaaat gaaagatcaa cgacatctga
453421 tattgagaag acaaactcct tagagagcga acatttaaaa atccccaaat acaatgttat
453481 aaaatccatg caaaaagaaa tgcaatcact ctcagagcaa cacaccatgg agtataagcc
453541 ctataaatta atacaacaaa tttacatttt ttcttctaaa aatttgtatt cgcaggcaac
453601 taagccttta ctgggttcaa ggccatcatg caatcaaaat tgggtagagt atattttcaa
453661 tggtaatgaa ttgagtcaaa atgaaaacgc tttctccttc atgttacaac ccatgcaaac
453721 ttttttaaca ttacagtctc atttgacctc atcattaaag gatacagaga ctttattaac
453781 cattaataaa gagccagtga agtctagaac ttcaaatgta aacagtaacc tttcccaacc
453841 tcagcaacaa gaaaatgatg ttattggaaa cgatacgaag caagatatag aaaatttgac
453901 aatcggcggc ggcaacaata acgatattgt tggtaacgat aatgataaac gtaataatat
453961 aaccgaaatc tttgatattc gcttatcaga aggtttaaat catttgatgt ttaggtgtga
454021 ggacaaaata tctcatgaaa cggaattcat gaatttctgg ataaatgtct taccatgatg
454081 actatctctc tcttcatagt cttcccatca tatgcatgta tctatataca acctatatac
454141 actttgtaat attatccatc ctcttcctct atatagatta aaactgttaa tattacacat
454201 gacaaaaaag ttgcgtccgt aaagaaaaag tacttaaaat gggtaggtta gttatgtagg
454261 gaaagatgta tgtaaggata tggcttaaca aagctgttaa atgaaaagaa tataatcgct
454321 attttttata ttattcaaat ctttttttgt attatagttt agattttgcc tgcgatagtt
454381 ttacagcggc gttatccaat acaatgacgt ttctggtcgt atcaattgtt tgaaaaacga
454441 caaccgagcc ttgcttccaa gctttaacct ttagagtatc acctgggaaa acaacattgg
454501 taaatctcac tttcaactcc tcatatggac cataatgttc aaacaatgct ttcgcactaa
454561 tacctaatgt acaaagccca tgcagaattg gcgtaggaaa tttaactgct ttggctagcg
454621 tgggatcgat atgtaaagga ttgaaatcgc cagataacct gtacaatgcg gcttgatctt
454681 tattcgtaga aatctccgcc tcaaaatctg gtacctttcc atgtggcact tcaaaatttt
454741 ggacagcaaa cttggctctt ttcccatccc tcacttcctt ttctggaggt acatgtgcgc
454801 ccctgatgaa gaacgatcct tcgttataag ctatgagttt cttagtttta atgtcataag
454861 tttcgaagcc accaacaact aaagcggctt taccattctt gtcaagtact tgtaaaggtt
454921 tagcaagtgt ctttagagtt ccattacttg gcattgtcgg cgtgcagagc ttaaaatatt
454981 gttctccatg cagtaacatt gcataattga agttatcgac taaattgtcc atagctagtg
455041 tggcagtagc ttgcataaat ggaatgacgg cgaacgtggg caaaacttgg aagtctggat
455101 cattctcgta ggtgtactta agctctttgc ttgtgcatcc aagtcctaaa ttgtacaaga
455161 tacaatcctt ggtagtgtac ttgaataatc catcatccaa ctcctttgaa gagtgcgctt
455221 tttgcacggc ttgcaaggtt gccatagaag actcctctgt ggagctcggg ttgatagtgt
455281 tgcgactgaa atcagtgatg tggttccaat tttctttaat ttcttccggt tcaatagtct
455341 ctttaataga aacataaccg gaacttcttt gccatctggt ttgcccacac caaccaccgc
455401 caacttcgaa taattggcca ataacccttc ttccagaata cttttgtagt tcttcagatg
455461 ccaacaaaac aacaagtggg gagacttgag atgcatcaaa gtggtttgat aattccttct
455521 ccgagaatat agtctttgtc atagccgttt ctgcatgagg agcgataaca ttaacaataa
455581 ttcctctctt ggcaccttcc agtgcaatag ttttactgaa tcctaaaatg gcggcttttg
455641 cagcggcata attggcctgt ccaaaattac cataaattcc tgaggtagaa gtagtattga
455701 taataaatcc agacttttgt ttggtaaata ttggccatac tgcttttgac aatgaaaatg
455761 tggaaaaaag gtggactttc aggacagcaa accattcctc atctttcatt tttaaaaaag
455821 atttgtcacg caaaatacca gcgttattga ccaagatgtc tactctctga aacttactta
455881 ttgcagtttg gataatgaga ggagcttcgg tgaccacatc atgggaatct ggaatggctg
455941 tgccttcacc atatagttta tttatttctt caacaactga aaaaggatcc ttgatgtcat
456001 ttacaactac cttcgcaccg taccgtgcaa accagattgc atgagacttc ccaagaccac
456061 ctcctgcacc cgtaactact acgactttgt tgcaaagcga cttgattttc actgagcctt
456121 gttcattggg aggtaatttt tttgctttgg tgattaaatc attataatcc gagagttgat
456181 atggatgctg agttttgtta aatggcttgt ccctatagtc tgtgatttcc ttccacttat
456241 ttaaaattgc ttcaggagta tatgtcttgg ggtctggatt gaaaatttgt ccagaagacc
456301 tctcccatct gagctgtcca aagaatccag cagcgagttc aaaaatggag tttgacactt
456361 tcgtactttc gtgtgtcaaa tagagtacta agggaacaat tttttccggt cctaactgtt
456421 tcaagatatg tggtggtaac acgttttctg tcatacgtga tctagccaat ggcgcaattg
456481 aattaacatt aatgttgtat ttggcaccct ccttcgcgag ggtttccgcc aaaccaacta
456541 agcccatttt agctgctgaa taattagctt gaccaaaatt tccaaataga ccggcagggg
456601 aagcggtgtt aatgattcta ccaaatttct gagagcgcat ataaggccaa gcagcacgcg
456661 atagcttata gccacctgtc aaatgaacat ctaccacaga tgcaaactca cgttctgtca
456721 tctttgcaaa tgaaacatcc cttaatattc cagcgttgtt aattagtaca tcaaccctgc
456781 cgaattcttt tatagccgtt tcaattattt tctctccatt ttcattaaca gagtcgtaat
456841 ttgccacagc tatacctccg gcttttttta tctcatccac cactaagtct gcagctttgg
456901 agttatgtcc tgaaccaccc aaagtgccac ctagatcatt gacgaccact tttgcacctc
456961 tgcttgcgta agctagtgca tacaccttac ctaagccccc tccagcgccc gtgattacaa
457021 caactctatc tttgaaggat aaatttccag gcatggctta ctcaaataag aaataaatcg
457081 aatgtttgtt tagcttcgta tatgtgtacc ttgcttaata aattagctga taagtccttc
457141 tacctttcaa cactgggagt aaagcagcca gaaacgactt cttatataat ttctttactt
457201 gtcttccttg tttttttacc ccatcctcct ttgctttctt gctgatgttg atccccgttg
457261 gagtaaaaat tggcaaataa ccgccgagag ttctagtacg gatacggcgt taacaaattt
457321 ccccgtcgat cactttcgga cttaaaacta ggcttccgga accacacaag attaagaaat
457381 taaggcttac aacaagactt gagagaagtg atcgaatatt aggatactct ttttgtttat
457441 gtaaacaatt accgtaacag actcgggaga atcagaaggg aagctgcctc tagatatcaa
457501 aatgaacgaa gtaaaaatat cgaagcataa acaaaacgat aaaaacttta gaaactattg
457561 attctcttcc agccttgcct tagctcaagt tcctgaatat tcttgttttt tatcgctacg
457621 tactcaattt ttaatgcacc ataactactc aacataacgg gttagtgaaa tctactgtgc
457681 tgctagaata gtatcacgta cagtagttta attgatagcg taaattgaaa aatcagctaa
457741 ataaattgtc atcaatttta caatagcaga aatgtagcga ttaataattc aataggaaat
457801 gaaagggact ttaaattcag aaataggtga atttatgatg attgttggga tttcttacta
457861 gtaatttgaa tagtagtcac atgatcgttg attattattc caatacaaat tttgtgtaaa
457921 gtcactcttt ccccttctga atggtgcatt cgtgaaagaa ttttcgatat tgttgtattg
457981 taaactagga atcaaaggta tcgttctata atgagagaag tattaaaggc acgcactgat
458041 cgattgtatc agatatgact atagctttag tgtttagagt catctcttca tacatataaa
458101 tgttgcaata aaaatcaact aatatctatg ttgtcatatt gagaaatggg tgaatgttga
458161 gataattgtt gggattccat tgttgataaa ggctataata ttaggtatac agaatatact
458221 agaagttctc ctctccggtc taggaatccc caaaatggaa tctatatttc tacatactaa
458281 tattacgatt attcctcatt ccgttttata tgtttcatta tcctattaca ttatcaatcc
458341 ttgcacttca gcttcctcta acttcgatga cagcttctca taacttatgt catcatctta
458401 acaccgtata tgataatata ttgataatat aactattagt tgatagacga tagtggattt
458461 ttattccaac acatataaag tttagaaaga tgacataaag attaacttaa tacatgactg
458521 ggtatacttg aattctaaaa ttttcaacaa ataagtggtt gtttggccga gcggtctaag
458581 gcgcctgatt caagaaatat cttgaccgca gttaactgtg ggaatactca ggtatcgtaa
458641 gatgcaagag ttcgaatctc ttagcaacca tattttatat ttttttatat tgtgttcaac
458701 aatgaacaat aatgacgaat aatccagaat gatataaacg tccatgaata aaagtccgtt
458761 ataatcatat ataattgatg cataccgtac gctattagtt ctcttttgtt ggttgctttt
458821 gaagatttaa ttatgatatc attaaccagt ctaaaaaatt actacaattc gccaagaata
458881 tttaagatat ggttgagaga tcccaacata attactgaca gacttactgg tcgtcttcat
458941 cactttcaac atatttaggt gtttggtact tctttgtatt tatttcattg tcatccacat
459001 ccagcattgg ttttccatta gaatttccag ctggtccatg acttgttttg aaattaattt
459061 ttttaacttg cacgttcctc gaatcagaat catcatccga atcatctgag gaagagctat
459121 ccaatgaaga ttcaagtgac atggaagaag aagaagaagg tgaagaatgc gacctggtaa
459181 ccttgacttt cttgagctgc ggtgttcttt ctaaactgga cggtatcgct tggccatttt
459241 ttctttttcc aggagttgaa ttcataactg gcaacttggg tgagacttgt tcttgttcct
459301 gagccgtact attagaagtt gcctccactt tgtctttact attatcaaca ggatctctca
459361 ttaatttgac tacttttatg gtcgaagctg catttggcgg tttcccagca ttggcaaaaa
459421 tatcttttag ggatctattc cccatatttc tttttctttt aaactctata actttcgatc
459481 caacatcatc agtttttcgt ttcactttta ttttaccaaa ttttgcgaat ttctcaccgg
459541 aaataatggt attgggatca tcaaagtgct ttgtttccag acttacccct tttgaagtta
459601 tggatttggg tttatctttc ttcattattc caaattttcc gtaatatggt tccgtaatac
459661 tattcctttt ttggacctta gtttccccag ttggcttgaa cctatttagt ttccgaatag
459721 tttcttgtat ttttacgtct tttgcatgcg aagtagatga cgcagcaccc aatgatttat
459781 caggaaactc cttctcaaca agtcgaaata gggcttcctt accttgactt tgatgtaacc
459841 gattattcaa ttctttttca ggaaaaaagg gaggagaaac aacatttttg gtactttgag
459901 tactttgtac tgcattttca atatcactgt tgaatgaaac gctatccaag tcggaattga
459961 tatcccgaaa tcccatcgat gccttcttag aattgttgat aaacgaatcc gcacgatcat
460021 tatcggtttc attaaaatcc tcttcatctg aaaatgcttc tatccttcta caattctcac
460081 ctatatcttt gtcgttcaat ggcagatcat cacctttttt gttttgaact ttaatttcta
460141 aggaactctt cctgggacta tgagcaccac tagaggggtt agaatattgt atatgcatat
460201 cagaattagt atgagaagta gtgctcaatt ggaagtcggt atcaatcgaa tcaaacgaaa
460261 tttgagggga gttttcatct gcgggttcat aatcagcatc ttctgacgaa ttgcgtaaaa
460321 gatctaaatc ctttgattcg gcccttttag cgccatcatt tttctgttgt tgagtggatg
460381 aaggtatatt ttctttattg ttatcactcc cttgcgttac aactccctct ttagcacgag
460441 cgtgatcttt tacgtctttg tgtacatttg atgccactac tgtggaagta agtggcatgg
460501 gacacttttc tttattcagt gcatcatact tgcttgcaag cggtagaatt tcgttcatta
460561 gcggcgttga tactcttgat ttattaatga agttattctt gagcgagctt ttagctatta
460621 gatgcattgt atctttattt gatatagaag ataagtcttc cttagagatc ttttttctct
460681 tttcagtaac gatggatttt gtggatggct tgttgtcctg ccgtctccgc tgtcttgcca
460741 attgtaaaag tgaaatatgt tgatttctac tccagtctaa ttcatctttt aaaattacca
460801 aaaccacacc atcattttca aatacgtctt ttattataaa ttcagagtcc aaatcacaac
460861 catgcctatc ttgtagagat acgatttcaa tggattcttt gaaatttgga taaagtctat
460921 caaatttagt taaaatttca ttagatagtt gtaaaagggt attgtcaccg tccgtaaaat
460981 gtaaaaactt tttacaattc gggaggtagt taatgaaatc actactacga ttcgactgaa
461041 tagaattttg cgaagacggg ctcgtaggag aggggtcgct acagttattg atactgttgt
461101 tgtgcgtaat tatatcttca ttatactgga ccataggaga cactgattgt ggagtattca
461161 agcgtgcttc gagaaatgtg ataatatctt gagcacttgg cggcaccagt acaatctgta
461221 acctccacat ttttatcatt tacttatttg aaccaaacac caaggagggc aaaggatatt
461281 ataagaaatg tggcaaaaga ttggcgtatt tattgaatgc ttgtataatt gggtagctaa
461341 ccaaaaatga cttgttttcc ttcttcagcg aaactaataa ataaacaaac aaacaaatta
461401 ggaccatctt gcatttgaga tctgaagaat atgaaaaaaa ttatataaca gtatcgtata
461461 atgcgacttt ttttcgtgat gcctatgtaa caatagtaga gaaaaaacag gtcacatttc
461521 tataaatgat tgaataattg gttctatata cgtacatact tttggagttt tacttttatt
461581 ctcttgattt aatggatgta gatgctataa aaagacatgt tttcccggaa atagttaaaa
461641 tgatattttg ccatttttat gcggatgatg gctattagga gggtttttag tgattttttt
461701 tttttccaca agctgaaatt ttcgaggtct ttgtctcgac caggctctca agtcaaaagt
461761 ttcatagtct tcggccatca atttaaaata gctttcaaaa tttgacttga tcagatcgtt
461821 tgtagcactt gaatgcatga aattcacgtt tggtttagac tcaggacctt tatagatgta
461881 gtctgtcgag acagcctcat catcggtact caaagatgaa ggagacagcg aatttaccgg
461941 agaaaaatgt cttgattcgc tttccagaga tgcggaaggc tcattgtttg agcacgatgc
462001 caaactattt tccttaagat tttgttcctg gatgttatac tttttcttca tcgagttatg
462061 ataatttttt aaagttgttg tcaaaagtcg cttattcgat aaaactttgg tctttatgat
462121 agcaatagaa acaatatttt tgaagttatc gaaaacctcc atgttgaact gttcctgttt
462181 tttcttttgt ttggcaatgc tttgacatat tttatcatat tgagaccaaa attgttcaac
462241 gtttagtttt gagagatctc tattcatttt ttctagacaa ttttgtaacc aggcccgttt
462301 atcataattt ttaaatcgtt gatcattctg gaaaacctcc ttccaggaag tgttcttaac
462361 cacgttagcg tcgttatcca cgtacaacaa ggcagacaac ttatttaatt gccaacgacc
462421 atcagatttc caaatgaaaa aggtgtcact tatttcttca tattcgagaa tgtagaaatg
462481 gggaatacaa ttcggcttca aatatgcggg tgcacaatct atcttcaaat tttctgttat
462541 ggtctcagaa gtttgcaact caatcccgta caattcttga atagaatgca cgaacttgat
462601 aacctgagtt aaagtgagac cttccttaat acaggtcaat ttaacacgtg gttgttcttc
462661 accagcgtat aagtaaacgg tttctaactt ggacatggtt tcctttcttt gtacttggta
462721 tttcttcttc tttttctagc tgtctgtatg agtacttaac tgtaacagaa tagtaatggg
462781 ttcaggctaa atctctttaa ttatggcacc tttatgctga tataaatccc tatacatttc
462841 ttaggggtgt gttttggttt ttggtctcat agttttgaca gcacgttgga acgccactca
462901 tgccttaaaa ggccgggtaa tgatttatag tccaattata tcacagcact acaagacgtc
462961 aaaaattcac ggcggcaaaa ggtctgtaac tacctaaaca ttaaaagcct ttgagctata
463021 aatcattatg tacactgaga atgccacatg ctaaaacaag gaagttttca gcgaagtagc
463081 acattaactg accactcaat agaaagaaaa cagaaagtgg aatggatggc cactttcatg
463141 ttatcagtgg tgattacttg atgacaaaat aacgctattc gagagcgagc tataattctt
463201 gaccaactgg ctcgaccttc ttcgtcatac tgtagatcaa aattctacca ttactggatt
463261 cttttttttt tttttttttt tttgggctag ctatgaacgt ttcctagtcc cgctcacgca
463321 ttctagttct gcattgggta aaagaaagca tatcattaag cggcagtttc gggtcgttct
463381 agcctcgagc aaaacgaagc tcagctcgcc tctttcacta tcatcctgtg ctcacgtcca
463441 tgcgcattct tggcaattct gcagagatct ctcatctggg tcttagcggt tctccgcacc
463501 ctggcgatgt gcttcgagaa cgtctttgtt catcacatag actgcactgc actgcgccat
463561 catctcgatc gatcgcgaga ctttcgcggc gacattcgcg aaatgccaaa tgaaatcgag
463621 ccggcctcgt gaaaaggtgt aaaaaaagaa aacgcatcac tgaaatggac cccgttatga
463681 aacgaatgag agatctgccc atagatcatc tttcctatag cgggaataaa catgtgtgct
463741 atttacagta catttcgtgt atctcacgca cttctctata tgtaatgttt ttgaaacata
463801 gacgtcgttc aaaggcaatg cttttgatct ttgtatatat atatgcttgt cgcagagtgt
463861 tacatattgc tgtgatggat ctgttggctc ttggtatcat cgttcctcga aacagcccat
463921 cataaaacaa taccattcct ttaataaaac ttacaaagat gaaattttct aaagtctcac
463981 tactggccgc atctgcatct gtcgctttat ctgccccagt tgctgtgact gtcacgcaac
464041 atgtccacca agctgccact gtagtggtac aaggtatagt tcgtgtagaa aatggccaga
464101 ctctaacgac gttcattacc aagggcactc aaacggcttc tgctagtccc gttgccacaa
464161 catcagctcc tattgtggtt gctaatgctc aagtggacag catagctact tccgttatcc
464221 aagaaagcgc tgtcgtggct gaatctgcaa catttgaaga atcctctaca gaaacatctg
464281 aagcattttc tacagcaact gcaaccatac aagcggtgca aacctccgca agtgccacac
464341 aggatgatgt aaccacaact ttaacatctt caacacaacc taccagcaca actactccaa
464401 caaccactac cactagccca accactacca ctagcccaac tactaccgct agtccaacta
464461 ctactgctag cccaaccacc gctaccacca ctcaatctac cgcctcaagc actcaatcct
464521 caagctccga tttctcaacg tcaatggtta acgaacacaa cactaaaagg gcgttgcaca
464581 aggataccgg ttctttgaca tggtctgaca cactagcaac atatgcacaa aactacgctg
464641 actcctacga ttgttcaggc aacctagtcc actccggcgg tccatacggt gaaaacttgg
464701 cacttggtta cggtacgacc ggctctgttg atgcctggta taacgaaatt accagctacg
464761 actattccaa ccctggtttt agtgaaagcg caggtcactt cacccaagtc gtatggaagg
464821 gaacttctga agttggttgc ggtttgaaat cttgcggtgg cgaatggggc gattacatca
464881 tttgttccta caaagccgct ggtaatgtca ttggtgagtt tgctgacaac gttatgccat
464941 tagcttaatc actgaattta gcgaatacat gggtatggac atgaacagca atgggcactg
465001 ttccttctct tacatttctc ttttatagtt tcaattttta ttatacacta aggattcttc
465061 ttttctaggg tacgcaaatt aaatgcaagc aagatcatat aacattgtca tagtctcatg
465121 catggtaaat agggtgaacg aaaaaaattg ggagatcttg ccgacggcta cgtatatata
465181 tatatatata taaatatata tatatatatt catgtatact gtatatgtac aatcatatat
465241 aaagttactc ttcccttttc tttttttttt tacattatta cgtatatact gctttattat
465301 cggaaagtag cagtttaatt aaagcaactt ctgttgtttt tcctctaaaa cacaaatcat
465361 aggatatcaa ctgcaacaag atgttggatc atttgtggat ggcctttgca aattaatgtc
465421 tacttgtccg ttattgcctc caccgatttg tctattttgc ttagagagaa tttcgtcttt
465481 ctttaaatcg tataattttt caccaatatc ttgaaaaatt tccttaaccc cttcacctgt
465541 cttagcacta acttctcgga acagcaaccc ttgttcttgt gcgtactgtt tcgcttcttc
465601 agtgctaatt gctcttactt tttgttcttc atctccacct tcgtttgaat ctgggcttgt
465661 ctcagtgcta ggcgtttctt gacataaatc cactttgttt cccagtaaat aaataaccaa
465721 gtcgtcgtcg cctaccttat ttttcagctc atcaacccag ttccttgcct tttgtagtga
465781 atcttcctgc gtaatgtcat aaacaactaa tgctgcatta gcgtttctat aatacattgg
465841 tgccaatgac ttgtatcttt cttgaccagc agtatcccag atttcaaatt ttataacgac
465901 atcctttgtt tcattaccat cgtttgggtg aatagtgatt gattgagata aaaaagcagc
465961 accaatcgta ctttcacgta gttcatcgaa tgtatcctta acaaaacgat gaacaatgga
466021 agatttaccc acggatgagt cacccaataa aactagttta aattgcaaca tctgttaata
466081 atatatacgt ttactccaaa taagttaaac cttcttccta ccctcgcact ataaaaaaaa
466141 atttagatat gtccagagct cgatatcgaa gcgacttaac aaataattaa tactgacagt
466201 tggtaaacgg gcctgttccc ttcactcccg tatgttaaca ttgtaacttc atatcgcagg
466261 ggcagagctt tataaacctg aattgtccgg ccagaatagt agtcgctgtc cacgaaagca
466321 agacactatg aagttgccgt ttggtctcaa tgatacacat agtgttaaga acattgagta
466381 atttggagtc agattgattt cattccttta caatcgtgat gtgcctattt aattcaaggt
466441 catgtggatt tcaaaattta acataatgat tttacctacc tttcacacat ttgaacatgg
466501 gaacgcttaa atattaatta ctgtgcttca ctacaattac aagagagtac gtattgacgt
466561 tattaccagt ttactttcca tcatacttat cgcagaaaac aaaatatcta aaaaaagtat
466621 agtaaacggt tgatgtcatc aagaagcata ccttactcct tatatagaaa gctaagagac
466681 acctagaaac attgatttgc caaaaatcca cattcctcga aatggggcct aaaatgtgcg
466741 ctaatgcgct aataaaggtg atataaagtt caaatcttga gtatacatat gacatacaac
466801 cataaggcct gattattgtc tatttactgc aattttcatc ttcagttcca atccacggta
466861 taatgaaatg taatgcatcc tatcttattt ttgaatgtat tatgttaatc gtcacgtttt
466921 ggtaatgatt tctagatgcg actatagcat ttttggcaaa tcaagcgttt attttgactt
466981 ttctaaattt ggctttaaaa tccctaaatt tcacagttac gacatcctta aagtggatat
467041 ctgttaaaat agttgaccca agtacttcac tctccccagg cattttgttg atgttgttac
467101 tgctcgcatt gtatttcatt atacattttc tcttgtcctt tgttcgctga ttcctttctc
467161 catgaggtga tatgttgagt ttaatcttaa ggtattctct cactagaccg tgcgcttcct
467221 ctttatggca atttttgcat gatttactat ttttattatt actattatca tttttactgg
467281 cggaagatgc tattttggtc ctaggtctaa ctacctgatt ttttgtatgt ctctccgagt
467341 gcttaccagg ttcttcgacc tgattttcgt ccataaccat ctgatcttta caatattttt
467401 tctcaaatgt ctgagccttc tccaatccta gcatttgttg ctcctttctc caaactctag
467461 cacatctttc actcatgtaa attggatcaa tatctttcat agtggtattc caagatatgt
467521 tgttttggtc attatcttgg ggttcaggtt gaaagtacgc gttttccatc ggtgttcctg
467581 cattatcttc actttcgctt ctagactttt gagctattcc gtcgttcgca attttaggtc
467641 tgtcgttatt tttctcttca ttgtcatcct ttactttatc cacttctgtt acatagccta
467701 ttaccacagc agcgcagtta ttaaaagtat tgacaaccct attagcgaga ggtgttttta
467761 tgatattttt caatcctgat gacgcttcaa cttcaatact atccattttt tttctctcta
467821 tcataatgtt ctcctgttcc tcaccttgca tcctcacctt ggcttcttct tctctccgtt
467881 ttttcctttc ctcgtgttcc ttgtaaggtc tcatgtcaac atagaatttt tctggttcta
467941 aagtccaaat aagattagga aggtctttat ctttaagctc tttgatactc aagttttttt
468001 tgttcaagtt ctgcggatca cacgctgctg tagcgttgaa tctgtaaact ctgacgttgg
468061 aaattttggt aagttgggaa aaatttgaga tagtagtgat tttattgctt ttcattaatg
468121 gttgtggaat gtaaatatca ccgaggtatt tcttcttttt atatcgtctt tcgacaaaac
468181 cttctgaata aacaaccttg tgaaggatgc tccaatcatc ttcctttacc ggggccatat
468241 caagaatcac cttttttacc ttttcaacta tataatattg atgataatag gtccattgtt
468301 tatgaataaa tataaaggcc ctgttcaatg gatgcaacgg atccagttca tctaggcaat
468361 cctctaccgg acaatcgaat tccacaacta aaacagcagg gctacgcctg actaagggcc
468421 caatttccat aatctgtctt aaagaaataa ccatagtata aaatctgtga atcatatttt
468481 tagattctct gaaatcttcc acattcaagt tctcgaatat cataaattcc ctccccagat
468541 ccttaagcat ttgaagccga tctttcaaac ttcgacagcc ttcaaattgt tgcaatagaa
468601 gaacatactt tccaaaggaa gagttgattt cagtaagagc ctcatatcca gaatagtcca
468661 gaaacatagc taaaaaaaaa tctcgtcaat ttttttttta actattcgag accttaccga
468721 gtaatcactt taaaacaaaa aataaataaa tttatggact attttcagtg actgatatgc
468781 caaattcctt tgccctgtat ggccatattt tcttaccatt tctgtggtga caaaggtgat
468841 gcaattactg acacaacaag gtaaaaaaga gaggcgggta acaaattaca cacgtccatc
468901 atccgctaag cgctttaagc ttatagagag gcaagtaacg tcattgatcc tggatgacaa
468961 acgtctttta ctcttttttt gggtccttct catggtttca gtgtctgacg aaaacaaaga
469021 aatatcatac atttcaatag agatcgaaat acatatccgc acagcatcca atataaccaa
469081 tacatttctt tttatcaact acttgatatg attccgttta ctataaggcc aggcaaatca
469141 aaatacgctc aagatctctt atcagtttcc ggaggtaatt ttcttgcatt tccatcttca
469201 cgcaatcgtc cgggcacata atacaatata tgctatacat caaacacgga gcgtggaaca
469261 tgttccagct caaaaacagt tagcaagtct attttcgtac gttccgtaac cattcttatg
469321 acaatagcat acaacaaagt tttcataata ttttgtaaga ttcatatact tcttacagaa
469381 aaaagagaaa taaatattgc aaaaaactaa caacagaaga aactacttgc aaaatagtga
469441 ttcatcaaat ggcttcttat agtacgtagt cggcaaagaa ccaatgcatc atagcagtgg
469501 acaagcagaa ttgaatcact ttagacgtgt agcagactca ttgaaccaat aaaattctaa
469561 gacggatttc tgtgcggaat cggaattaag ggttgtcaaa aaagtgaaaa ataatctgaa
469621 attaaaaact gttcttattc tcgaggaagc tattcacagt aaaggaacac aaaaggcata
469681 agaacgcatt gaaaagtcta aaaaactaat attcgtatga tgctaagaac tactgcctca
469741 cgaaaaattg tgctaaggag gggtctagcc agcataaaca cagggactac cgttgcatca
469801 aaaaaggctt cgcacaaatt tcgcaatacc ctttggacta ttgctttgtc agcgacagct
469861 ttctacgctg gaggtatcat atattcgcaa aaaaatgaca aatttggtga ctttttctct
469921 aataacgttc cttttgccga ggatttacta gaaacatatg aacactatca cgataggcca
469981 acattgtttt tagaagattc ttgggacggc ttgaaggcaa agagcaatga tttattatct
470041 ggattaactg gtagttcaca aacgcgcaga tctaataggg aaaatattga agtaaaaaaa
470101 atcttatcat tagaaccact aaatattgaa acagaaaatt ctgatccgca actgaaagaa
470161 atcattggct ctttgaatga tctcatcaac agtctaaatg actcaaacct ctccatcccc
470221 gaatcagaat tcaattcaat caaaaaatct aaccagaata tgcttacgaa tctatcccaa
470281 ttaaatgaaa cgttaaaaga ggctttatcc aattacatga tacaaagaac atcagaagta
470341 atcacggaat tgaacacaca atatgaaaac tcgaaaaggg agtttgaaaa gaatcttcaa
470401 aaaaacctat tacaagaagt agacgaattc aaagaaaact tgaccaagca aaaggacaaa
470461 gaactagaag aaaaattaaa ggcgaacgaa gaattgttac aagccaaaca tgcaaatgaa
470521 gtgggcttac tatccatcac tcaagtcaaa gaatttaata aaattatcaa agacaaaatt
470581 gagaaggaaa gaaatggcag attagcccat ttagaggaaa taaattctga agttaacgac
470641 ctcagcaaat ccatcgacag atcgagcaaa atcttaagta aaaacgaggc tctagtgcaa
470701 ttaactttcc aagtagatga gatcaaatct aggattaaca acaataactt acccgatgtg
470761 aatatcgaca aggaactatc cagattgaaa cttctttcca atcttctctc taccttcaac
470821 aaaaaatctt gttgcgacga tggcgactgc tgctcctgca aaaagggtaa taagaatgaa
470881 ggcaaggaag ggaagatatc atgcaaatgc aaaccaaaga caaaccctcc atcgctatta
470941 agcgtagctt tagatgaatt agaatccaca tgtagcggta aaaaaatctt atcgaatgag
471001 cagatctata acaggtggaa cttactggca gatgacttta agacagcctc tttattgcca
471061 ccaaattccg gtattttggg gcaattaacc gccaaagttt tttccctttt cttattcaca
471121 aagacaggta atccttcaaa tgccacggat ttcgattctg tttatgcaag agtcggcgat
471181 aacttgaggg tatccaacct caacgatgct gtagaagagg ttgtctccct aaagggttgg
471241 cctcataaag tttgcgaaag ctggatcgaa gatgctagaa gaaaattaga agtccagcgc
471301 ctggtagaga ttcttgactg tgaaataagg acgttgtgaa agaataatac aaagagaaaa
471361 gagatgtacg tcattacacc tcaatttcca ctttgtttag gaggctttaa taaagaagaa
471421 ctaaatacct aaaatgtaag ttagctgtta ctcgtcattt ccgattcaaa gaattttgaa
471481 atctttttaa aacaatataa ctttgtagga attggaacaa caatgtgtat ataaatagta
471541 tttcaacgac aaatacaggt tcaaataaat aaaaaaatac gaaaatatac aaaaatgcaa
471601 caacgtttaa actccaaaat aaccaaacat cccgcagtac aaaaaacatg aataaaacaa
471661 cagaataacc aaaacaatac taaaacaaaa cattcattct gcagctttgc aaattccctt
471721 acatagcagt tctctaccgc attccattaa tgcagtggtt ctattttcca catatccggc
471781 cttattataa aactctggtc ttcgtttcat gatcacttcg ggggttttta tttgcaatag
471841 ctccgatagc gattccactg cgttggctaa gagcatttgg ttatcaacga aaatcttcgt
471901 caaattatga gatgcatccg agtaatatgc cacggcaaat gaccatttta atacggttcg
471961 tccctcattc aacactttta aactttctga taggaactgt ccatcaatcc atgagatacc
472021 tattctttct tgtagtgcat gaactttcgt gcccaaagtt tgccccaggt tccaatcaag
472081 cttggctgaa acttcatgtt cgttaaacaa tctatagtag aaagtgtatt tcttcaaggt
472141 tttattagcg tcttgagggt tcttactttt attatcctca ttattcttat acattgtaca
472201 ttgaaaaaag ttcttaccgt ggggcgccca ggggccctca caaatccaac agaattcgta
472261 tttacaactt gagcaaacca tgtggttgca gccaccattt ttttcaatat taacagaaca
472321 ttttggacat tctttagtgt gggacaagac ccaattcaaa atttctgatt cttttctggc
472381 ttttttaacc caagcagtgg ttattttaca atctgctggg gaatgaactt cgaatccgca
472441 attgaaacag aatctatgaa atgaattaca cttaacgaaa ggtgaataat gcaaacgggt
472501 atattctggt aatgatgacg tatctcgcaa gtgcacgatg gatttacagt cagcaaacgg
472561 gcaccattta tagttacgat tatgtttttg aacaaaactt ttgattgaag aatccatcaa
472621 cttactactc gaaggatgtc ccatcacttt atctatatct tcatttttca atgccaggga
472681 acagtccatg catgtaatga tgttcccctc atgcaactta tccttgatgt aatgacggta
472741 gcaattgata caatattcat ggccacattc caacgcaaat gtttccgtat cctttttatc
472801 acaacaaata atacatgtaa agtcattttt gaattcaact tctctgaaat gtgaattata
472861 atcattatct ttcttgatat ttgctgtggt acttaagcca agctccacaa gcaattcgtc
472921 cattttttcg gtccaaactt ctagcaaacg ttcctcgttc caatcataat gctgtagtaa
472981 tatcaatata tccgcagatg gaattgcaaa aataggttgt aaatggtcaa ccctttgaag
473041 cattctttca aatataccct tggtggttaa gcattcataa ctgagattcg gtacactccc
473101 ttcacacagt attcttttgt tgtttttcgt aagaggagca tctagcatcc cctcatatat
473161 ggtatcgact ccatcttcat cttcattgat gtcaaattct gaatcttggc ttgttacact
473221 aattaacttc gggaaaacta gtccatgtat agtaaattca gatgtattgt gagattcata
473281 aagttcaata gagctggaat cactttcatc aaaactataa aattgatcat tttcggtacc
473341 actactcatt gttaaaagcc tctaacaagt acacccaaat tcgctaaaga caaattaaat
473401 atacttaaag aatggctata attcctgtat agtagctggg atagtaacaa atcaatacaa
473461 atgtagctac cttaaaacta aggcagtact cacagcattc ttcaccttcc tctcctcttt
473521 tctaaagcgg gttcctattt tttgcgcaag gaggaaggac gatggcactg agaaagcatc
473581 aaatcgtatg taattaaact acgcaaggta tgtacggtca ataagtatag cttagcgctt
473641 taaaattagg tgggacatta ggaaaactaa taggggaaaa tatttcttaa aaaaaagggc
473701 atgagggctg atcaaaactt gattacaatg aatggtcaac gcggtcaatg gcagccttaa
473761 ttttcatacc tactctcgta ctcaattcat aatcatctgc gtagccctga gccctcagta
473821 accattcttt actctctgga aggccatcca tgccctccaa cttccatgta aatagagcac
473881 gttcataaag tgcagtcgga taggcccatg gatcttcagt tttctttata tatttgacct
473941 tgccattttg aatggagaaa aacttaggta gaaccttttc atccaatata tcacaacctt
474001 cttggatatg acctaatctt cttaatgtca aagagaccaa gagatctttg attaactcct
474061 gatctgagtc taaagcttca atggcgggat ttctatactc agttagcatt ttctttgtta
474121 gctccaaatg ctcttcagac attctattat aaccattgta gaagtacgca atttcgtgta
474181 ctggtgaagt agcgatacca tccagaggat tttccacccc aagttcctcc tttttcgctt
474241 taaattgctc aacttttctc agaataaacc tatctaatgg caggttcttc gatttgaagg
474301 ttttcttacc tagcaaattc acagaggtga agataagttc ttcggccttc ttttggtatt
474361 catccttttt gtctgacttc attaatccca tttcgcacat tctccaattt tctaaataac
474421 agcagccagc aaaatatgtg taaaaagcgt gtgaccaatc actgatgtct aatagcgata
474481 aaatatcttc tgcagctcta tcgtattgat gcaaatggat caatgttata gcacggtcaa
474541 aaatcatcaa ggatttgacc tgtctcatcc gtatcttgct aacatcaatc gaatccatca
474601 atgcgactgc ttcctctaaa cgccctttac cagatagcat ccttgcctca ttcaataacc
474661 atagcgcact attgggaaat agcgctcttg attgcagcaa cgcatcttcc agtattttcc
474721 caggatgcaa caacgtaggg ccatccatct cttcatcttc agaatcttca ctgttactgg
474781 aatccttaac tgctgcagga atatcaaaat catcgtcagt gaattggaaa ggtccatcat
474841 agtaaaacat cagggctaac aaaccaatac aaccatgcac gtttctttgc tttgtggctt
474901 tccaaacaag tctcaaacct tcttctctgg aacccctgaa tccaaccaca gataggaccg
474961 cgccaatagc gggtggtaat agtgatatca caacctgtaa aataccaaag cataaattga
475021 caccagaatg gacaaactca tcaattgttg cttgacttaa atctatatca tccgaaagaa
475081 ctttatgatc tgttatttcc tcttctggca agtcttccat tgcttgtagt cctagctcac
475141 ctctcaacct gttaattgca ggagagttgc caatgtgggc gccagataat ctttcagtcc
475201 tcatgctatg aatttgttca gcaaattgta aaagatcctt atccttttgt tcttcaggag
475261 tcagttcata aggtatatca acggaattga acgcatcgcc accagttatg aaagtcgctg
475321 gggtggactc cttatcttca ctgcctgacg taattttcaa tttcttggct ttgttagcag
475381 ctttaatagt ttccaagatt tcttgtaaca tatagtacga ctttctgagc tttaaaatgg
475441 ccttggccgc ctccatcata ctttcactga aaatcatcaa tagggcatgt agaaggcatg
475501 attctgtata agtcacggca taaactgttc ctggaggata taaagaactg ctcttcaatc
475561 caattttttg agccctctct ctacttttca aagataaagc ttctgccttg gccaaagtcg
475621 cagaagcttt tttcatctct tcagcttcaa aacctaaagt ggcctccaaa aattcaatga
475681 caccacgagc taacgcattt atagtttggt cggaagcttc tttagcatca ctctcatcca
475741 gcaaagccaa accctcgtca gcattatcat ctaagacata gtccatcgca cgcagtgcct
475801 gttcgaaatc atgagcttgt tttagaatgg ctttagtttt ttcttcctgt gaaagctcag
475861 gaatctcttc cttcgcacca aaaccaaaca ctttaaacat tttggttgtt ctgtgatcca
475921 ctagtcacaa ttagcctgtg gatcgtctca gtggtggcat ccgaataaac gatgcctctt
475981 ttttagttga tcgaatttgc ccccttcctt ggaaaaaagg aaagaaagca aaaagccggg
476041 aataataata acagagaaga ctaatagaca tttttttagt aagattggcc ttatctcgaa
476101 caagatttct gagatgacaa ttcgattagc ttaacagtaa caagtggggg aattacgcat
476161 tatatatata tacttctgta tatgtctacc tacgaagtgg tgcgagtcac actcgtcacg
476221 acgagctatt gtggtctaca agaactacac ggttttcctt cttgatattc ttgatttctt
476281 ctttcatctg ttttctcttt tgtttggcca tcgcctttag cgtactcact ggcacaaccg
476341 tggtggaagc atatctatct acgctatccc aaacgcattg ctcgacaaca ttgggaagtt
476401 ttctgccata caggcactga tcgaccagcc acatacccac aataaaagat ttcctatcta
476461 aagtaccatc ttttcttgtg tctaccttcg tgtaaatttc tgccaataga ctattgggca
476521 agttagaccg cttccagata tcacggacta tgatacccaa tatcaatcca tcttcgggta
476581 aagtattaat tgctccggaa tcacccgtta tagagggcca ccagctcaac aggttcaaat
476641 gacggtgtct gttgcttacc cacatgcttt cgtaacgctt cctttcgttg tctgttacga
476701 aagttatatc tgtatgtgat ttccagggtt tatcctcatt gaatttccga tctctcgtgc
476761 ggtggatagg cctatgatgt gcagttttat tggcagaatt cctgatcttt ctcttaattc
476821 tatctctttt gcgtggcttg gtcaaggcgt cctggttctg atcagattca gaatcagaat
476881 cagtatcgtc atacacatca tacgtgtcgt tggacggatt gtacttatac ctcagatttc
476941 cctcatgtag agaggatgca tgatcatttt ctgcgtttgt acttacagag gttttacgta
477001 atgttgtttt aaatctcata ctcggttgtt gttcatgttg tcccagttct tcgctgcttg
477061 catccatttc atattgtgaa gataagtgct tgggcttact accaaatact ttccttttga
477121 acttgttaac aagcttcttc ttcctcatat cggatgaata gttcggaacc aagttgggca
477181 aaccacttcc ctggttgctc gttgtagtag tagtgtttga gcttgcaata gatggctctg
477241 attcacataa cgagagttga ttaattgttt gagatagact tgtttgtgac ctattagaaa
477301 taacgtctga agtgtccgga ttgagactat gtctggaatc gatgctaatt gatgataggt
477361 tttcattttc atgaagctga ccactgccga caagtgatga ttgcaaggga ggagacggcc
477421 tgcgtttggg cagagctttg ttgctgtctt tattagttgc aggctccata gagctcgagg
477481 atagccttct accgctacta aaggaagtaa gtaaattctc ttgagatcta ttgtcgggag
477541 ttctttggcc aggcgtcagt gattcattgg agccgtttct tgagcttgag cgtgaatgaa
477601 tgcccagcaa gccattcaag ttcggagttt ctagaacttt tagtgtatcc aatgccgaag
477661 aatgggagga gttattgtca gaactaagtt tcgattgtga atgcgctaaa gcagctgcca
477721 tttgagcagt actactaaca ttatctttac ctgcagggct tgacctgtgt ttcttagaca
477781 actcaacatc attaggcgcc gttgttttaa tcttaggtac ctgttttgtt cgtatgcgtg
477841 ccttcttttg ttcttgtttc cgccctgact tttgtagcga tggctctgat aacctagttt
477901 gaggattcct gctcaccgtt actggagggc atggactgct gacctcattg gaatggttct
477961 ggaagatagc ttgcgcagcg cgaagggaat ctgaagctcc ttgttcagtc aaagttactg
478021 ttgtaccgcc atgataacgc tgtttaccaa acgaaagtct catactcctc tgctaatctt
478081 ttcctatgtc aaaaaaatga atctacccag gccttaaaag tatgttctac ctgtgcaacg
478141 agagtgttgt tgtggcaagg gtccattaca caatgggcct ttttgtgatg attcaacttc
478201 gatatgcttt atacgagaaa tcatcgaatt ttcgctgcgt ggaaacaaga ggcagtaagt
478261 tgtacgtata ggtgaggctc tgcatagaag aggcgtattt gcggtgagac ggaatctgac
478321 gaggatatta agtacagatg gcagaacaaa ttagtcacaa aaagtccctg agggtgagca
478381 gtctgaacaa agatagaaga ttgctcttaa gagaattcta caacttggaa aatgaaccga
478441 ataaaggtcg tcaagaagca cgtatagggg aaaaagccag cgaggctcat tctggggagg
478501 agcaagtcac agatgtgaat atagataccg aagcaaacac tgagaaacca gtgaaagatg
478561 acgaattgag tgcaactgaa gaggatctca aggaggggtc agaagatgca gaagaagaga
478621 taaagaacct gccctttaag aggctagtac aaattcacaa taagctcttg ggcaaagaaa
478681 ccgagactaa caattctatc aagaatacca tttacgaaaa ctattatgac ctaataaaag
478741 tcaacgacct tctcaaagaa attacaaacg ccaatgaaga ccaaattaac aagttgaagc
478801 aaacagtaga atctttaatc aaggaactgt aatttccagc ggcatatcgt ggctttcacc
478861 gaacacttcc ttcgagagag tgcattttac tatgtgaacc aatttttcct ctttttcggt
478921 ttgcaagttc acctgaaaaa ctgcttaaca ctactagcaa ttgccctatt gtcgtacgag
478981 gactttgcca aatgtattcc cggctgtttg tagtatatat acgcagatat ataatagcgc
479041 cgtcttttta cctctttgag cgaattgcca aatattgact cttttgtctt atttcgctat
479101 ccccatctta tcaaaaatgg gaacaactcg ttgaaataag agacaagcaa caagaaagac
479161 aaccaacaga aagttccatt ccgcacaaat acgctggaat cccatagaat attgcttgtt
479221 cctctatgac tacatgctcc aattcaatac agaaaatgat actgtagctc cagtgtttcc
479281 catggagcaa gatataaatg cagcacctga tgccgtccca ctggtgcaga caacaacact
479341 acaagtcttt gtaaagcttg ccgaacccat agtgttttta aaaggatttg aaactaacgg
479401 actgtctgaa atagccccca gtatcttacg aggatctctt atcgtcaggg tgttgaaacc
479461 gaataaatta aaaagtatat cgataacctt caaaggaata tccagaacag agtggccgga
479521 aggtatacca ccgaagagag aagaattttc agatgttgaa actgttgtca atcacacatg
479581 gccattttat caggcggatg acggcatgaa ttctttcacc ttagaacatc acagctcaaa
479641 taattcgtcc aatcgcccat ctatgagcga tgaagattat ctacttgaaa aaagcggtgc
479701 ttcagtatat atcccaccaa ccgctgaacc ccctaaagat aatagcaatc taagtctgga
479761 tgcctatgag cgcaactcat tgtcatccga taatttgagt aacaagccag tatcaagtga
479821 tgtttcccat gacgacagta aactgttggc tattcaaaag acaccattac catcatctag
479881 tcgaagagga tcggtaccgg caaattttca cggtaactct ttgtcacctc ataccttcat
479941 atctgatttg tttacaaaaa cattcagtaa tagtggcgct actccaagtc ctgagcaaga
480001 ggataactat cttacaccat ccaaagattc taaagaagtt tttatttttc gaccgggcga
480061 ttatatttac acttttgaac agccaatatc gcaatcttat ccagaaagta taaaagccaa
480121 ttttggttcc gtggagtata aactgtcaat agacatagag aggtttggcg cattcaaatc
480181 aactatacat actcaattac ccatcaaagt cgtaaggctt ccttctgatg gatccgtaga
480241 agagactgaa gctattgcaa tttccaagga ctggaaagat cttcttcatt atgacgtggt
480301 aattttctcg aaagagatcg ttttgaatgc atttttaccc atcgatttcc atttcgctcc
480361 tctagataaa gttactctgc atcgtattag aatttatcta acagagtcta tggaatacac
480421 ttgtaatagt aatggaaatc acgagaaggc tcgtagatta gagccaacta aaaagtttct
480481 gttggctgaa cataacggtc ctaaactgcc tcatatacca gctggttcga atcctttgaa
480541 ggctaaaaat agagggaaca tcctcttgga tgaaaaatcc ggcgatctag ttaacaaaga
480601 ttttcagttc gaggtgtttg tcccaagcaa gtttacaaac agtatacggt tacaccctga
480661 tacaaattat gataaaatca aagcccacca ttggataaaa atttgccttc gtctttccaa
480721 gaagtacggg gacaatagaa aacatttcga aataagtatt gattctccaa tccatatttt
480781 aaatcaacta tgctcacacg cgaatacttt gctaccgagc tacgagagtc atttccagta
480841 ttgtgatgaa gatggtaatt tcgcaccagc agcagatcaa caaaattacg caagtcatca
480901 tgattccaat attttcttcc caaaagaagt tctttcgtct cccgttcttt cacctaacgt
480961 gcagaagatg aacattagaa taccgtctga tcttccagta gtgcgtaata gagctgaaag
481021 cgtaaagaaa agcaagtcag ataatacctc caagaagaat gatcaaagta gcaatgtctt
481081 cgcatccaaa cagctggtcg caaacattta taagcccaat cagattccaa gagaattaac
481141 ttctcctcag gcgttaccat tatcgcccat cacctcacca attctcaatt accaaccatt
481201 atcaaactcc ccgcctccag attttgattt tgatctagct aagcgcggcg cagccgattc
481261 tcatgctatt cctgtggatc ctccatcata ttttgatgta ttaaaggccg atgggattga
481321 attgccatac tacgatacaa gttcatctaa aattcctgaa ctaaaactaa acaaatctag
481381 agagacattg gccagcattg aggaggactc attcaatggt tggtctcaaa ttgatgactt
481441 atccgacgaa gatgacaatg atggcgatat agcatctggt ttcaacttca agctgtcaac
481501 cagtgctccg agtgagaacg ttaattcaca cactcctatt ttgcagtctt taaacatgag
481561 tcttgatggg agaaaaaaaa atcgtgccag tctacacgca acatcagtgt tacctagtac
481621 aataagacag aacaatcagc atttcaatga cataaaccag atgctaggca gtagtgacga
481681 agatgccttt cccaaaagcc aatcattaaa tttcaataag aaactaccaa tacttaaaat
481741 taatgataac gtcatacaat caaacagcaa tagtaataac agagttgata atccagaaga
481801 tacagtggat tcttcagtcg atattacagc attttatgat ccaagaatgt catcagattc
481861 caaatttgat tgggaggtaa gcaagaacca tgttgaccca gcagcctact cggttaacgt
481921 tgctagtgaa aaccgtgtac tggacgactt taagaaagca tttcgcgaaa agagaaaata
481981 agtacattat tttcattctc cgacagaatt gctaccattt tactttgtgt cctgtgattc
482041 aatagtgtac aatatattgg acattttata gtatacaaat atacaccatc aatctataca
482101 tccatatcac ttgtcgtaaa gatatccctt tttaatagta cagcgattaa aaaaataaca
482161 tgattaacgt tcagttacca atgagcttat ttattaggct tgctttagat ttttccaagt
482221 caatttttgt tttttctaac gcttgcaacc tcatctcaac cttcttcctt tgcaagcaga
482281 tcttcgaaac catctcgttt attctctcaa tgctgttccc actttcatca tcgtctggga
482341 aaagtaccgg taagggcgtg atgattttct cattcgattt gtttatattt cctttgctta
482401 aaagctgggt ttcccattct tcattagttc tgtagggcac ttcatttatg gccttctcta
482461 taatctttct tttagaatcc ttttgaatag caatttgatt atccgtgagg gctagcattt
482521 cgtcttgaaa gccttgcatt tcatcgtcac tgaagttcgt aatctccttt tcattgttac
482581 gtttcagacc accatttaat cttattgtct ccataatttc gcgtttatcc tcactgtcca
482641 acaattttac ataatctctt tctgttgtaa catcactctc actaattttc cttctagata
482701 atgacttctg tgctttcagt tttgcaattt ctcctcgggt tggtatacta ctaatgtgct
482761 caccttcgga gctactgcca gcctctgaag aatcacttaa tagatgatga ttcccctcca
482821 tcaagtcctc catattgaga attagcaaat catctttgtt tcgcgtcgat gcattggtat
482881 ttttctttga atggtaaaga tcttcataat gcgaattatc ctcctttatt gcttgttcgc
482941 catcaaaggt aatgtcgcgc ttaggaactt ttttaaactt tattggttgt aatacacaaa
483001 tgtcgttgtc atcatcttca gaatcgttcg acactagggg cttaatttgc tgcattggct
483061 tatgcgcaga accatcaatt ccaacctcct caggagaacc acttggtaac ctaattttat
483121 ttcttttctt gatcgccata atgtgttcaa atgctataac attgctaggc agaacttgac
483181 gtaactcgac cagttatatt gcttcttcaa agcacaaatt tatgatgatt gctttcagtt
483241 atgaggttca tttcgatatt ctttatgatc ttcgcttgcc gggtatcgga caaatattga
483301 aatattatac agcaagaaag aggcataaag agcctggcag cagcaaataa tggcaaagtg
483361 aacgtagtcc gagaaacagt ggcttaatta tttaaccttg ggtttgcagt aattaataat
483421 gacaagaaag caggctattg actatgcaat caaacaagtt ccgcaaatat tgcctttgga
483481 agagtctgat gtaaaagcgc tgtgcgaaca agtactgagt acatcatctg atgatccaga
483541 acaaattgct tcaaaatttt tggagttcct aggtcatgaa gatctatcgt ttgaatttgt
483601 aatgaagttc aatgaattat tgaatcagaa tgataaaaaa gaggaaaaaa aaacgaaaaa
483661 tgtgcatctt gaacatactg cccccacttc atggaaaaat gaatcaaaac agcccactaa
483721 taactatatc aataagaagg gagatgaaaa accaaaaaaa ttaaaggatg agaagaaaag
483781 ctcgacaacg aggcctaccg ttcaaccatc aaatcaatct acgcaatcaa accccataaa
483841 ggagaaaaaa gagcacagat caaaggggaa attacaatcg ttacaagaaa tagacgaagc
483901 aatcaagatg ctagagcttc gagatagcgg ttcttctaaa aattgtaatt gtcaaggtac
483961 aaggcatcca gttttcgaca tcgcgccaaa ctgtcttcac tgtggtaaag tggtttgtgt
484021 tatagaggga ttgaataaag gtaaatgcgg tcattgccat gaacagttga tttctgataa
484081 cgaaagaacc caaatggtag aaattttaaa tcaggaaaaa aacgaactaa acggttcatc
484141 atcgtcctta tccaatgcgt caaatggagc taatgtccca aagaagaaga ctaaaaccta
484201 caaaataact tccggtatgg gtaaaaattt atttgctgaa caggacaaat tatttgattt
484261 catcgaaagg aaaagagaaa gagaaagaaa gcgtaatgaa gtgttgaaat tgcaggagga
484321 aaaagaagag agcgaagcaa aggaaagaca agcgagcgag catgaccata aagctgagga
484381 aaacccggag ttgttagcag cacaagaacg attagataga cttttatatt tccaagacac
484441 ttcggcagaa agaacaaaaa ttattgataa tgccagcgat tttgacatga atcaggaggt
484501 gggtttatgg ggcagcgcaa gagaaagagc tcttgcgttg aagaagcaac aacgtaattt
484561 gagaaagtgg gaaaaagtag aaaaggaacg gaatggcagg cgcgagaagt acgttgttag
484621 catgaatata ggttcaaacg gtaaagttac tatgacagaa gtccctaagg atacagagaa
484681 cgtaattgca ggttcagatg atgacatcag tgatataagt gacgaagaag atatcagcga
484741 ccttaaacat atacacgctc tgaaaagtga aataaataca acgaaatcct tggagaattt
484801 gcatttacag tccaaagcat gggattacga acgtgataaa aaacaattcg ataggcctac
484861 gtatgtgaaa aaaaattcag atactgcaca acagaataga aaaacggaag aaaaggctca
484921 cgacatgcaa gcttatgatt taaagtcaag agtacaagtg gaccaaaatg cagacgcatc
484981 agtagaacag aatattcttg ctgtactttg atgaatggta aaagtttata ttatatatga
485041 tagaggatat aaccgttatt cattttctgt agattttatc attttctttg tcttcatagt
485101 atacaatttt tttttatatg aattaatgct tgttcttgtc tatttagtag ttaaactcac
485161 ttgctatttg cttctctgcc atacgagcca tacgaaacat tttattttta gagttttcct
485221 tagttggctt cttttcacta ttaccatcct tactactttg caatcccata gcctttggcc
485281 tttcacgtaa cccaaaactt ttagctaaat ggcctagatg taagaacttc acgttgaaaa
485341 acttcttttc ttgagagata tgcgttgcgt aagccctcac atgactaatg aaacctttaa
485401 cggccaaatt tttgaatgcg gaatctccca ctactcgtct ttctatattc aaatgccatg
485461 tcgtagcatt ggtatcccac tcatattctt tatcgcccac gtctttattt ttggacgatt
485521 tctcatcttt tctaatgaat ttatcatttc tgttgacatt cacatctttg aaagccggca
485581 ttagtatttc tttatcgaat ttcagtaatt cccaacccat cggatgatac ggctggatat
485641 agtccatata tttttcttct tcgccaggaa gtaaaaataa caaactttca cccttctcac
485701 cggcccttgc tgtacgacca actctatgta aatggtcttc aacagcaaat ggtggatcca
485761 actcaataac agatccaacg tggggaaggt ctaggcctct acttgcgaca tctgtacaga
485821 acataataag atgttttccc ttggtggctt cattatcacg agcaaaatgc tgcaatgtag
485881 aggttctcat ttgttgggat aaagaaccgt gcaatttata aatcactaca tctgggtccc
485941 tagaatctga aaaacaagga aacatagtgt ttccttttgt caatagtctt acagaatcac
486001 ccgttagatt tttatggtgc ccgtcacttc ctgaaaatgc gtcataatga aactccacgc
486061 tgtctgaaca tgatacgaat acgattgtac gcagcgtttt ggactgttga ccggaagcga
486121 tgaaatcttt ggtaatgttg ttcaaagtag cagctaatgt tacaagacgc aactttggtg
486181 ggacaatagt aatcctctgc aatagttgat cgggcgcaac cgttactata tcagaatctt
486241 tcttggtacc gttgctaatc aatttgtaat ctttcaacgc cacgtttctt aacctattaa
486301 caccatcagt aagtgtagca ctacataaca tgtgcactaa cttatgcggt agcttgggaa
486361 atttttcgga gttgatggga atatcgtgaa caattttaat aatttcactg atcgtctcat
486421 caaaacccaa ttccattaac ttatctcctt catccaatac gatatacctt agagattgac
486481 tcaattgctc cttgataact tttgtatttt gtaaatgatc caaaacacga cctggtgtac
486541 cgattatgaa attgcaaccc ttacgcaatc tagctttttc tgatttctta cgttctccac
486601 caatcaataa acatgggacc aagtagtgac aacatgacac aagcgtggaa caaacatgat
486661 atatttgtga tgctagttct cgtgtaggag caataaccaa tgcaaatgca ccagaagtac
486721 gatcaacatg agtatccatg ttcaaaatag tagatattat aggtaaaaga tacgataaag
486781 tcttacctga gcctgtttgg gcgtgaatga aaaaatcgtt cttccccgcg ttacctatta
486841 tttgaggtat ggcctgcttc tggatgctcg taggcttttt aatacgcatt ttttgctcca
486901 gatgagaaac aagaagacta gagacaccta aagacgcaaa ctgatcacct ttcaagggcg
486961 cgttagacgg attgatggca acgttttcat catgaatatt agtgtttacc gcagttgtaa
487021 tctctctgtt agatgtaaac agggatgaaa caaactgaga atcggctggt agagttctcc
487081 cttgagtgtt atgagcattt ctacccttat atttttcctg ctcttcagaa ctataggaac
487141 tctccttatg caatttttta atagaattct cgcctctacc cggaattatc ccttcgtccc
487201 ctgtagtgtt cgcctttctt ttcctcgaga ctgtcttgcc ctcaagcttc attttcattc
487261 ttcttctatc cttccatcta ccgcctgtca ccttggcagc ttgcttatag gaacttcctg
487321 cagtgtcctc attggtagtg aagtttaaca gcatagaatc ttcatcgctc atcttggtgt
487381 taaattgctg aataagtatg cttatttgga atatgaataa tcccaaagga aaaagaatat
487441 aaacaatcgt actttcttaa attagaaata tcacatacaa gtactcaatc ttttattttc
487501 ctaagctcat cgcaaatttt tcaagtaaaa tggaaaccta atatgtcagg gtttttaatc
487561 catattgtta gggcaacatt caattttaaa ctgaaatttt ataaaaactc tgttcatttt
487621 tcaggcctta gggttagtat tctgacaaaa ttattcaaga aaaaaagaaa tgttacaatg
487681 aatgcaaaag atggataaaa gcgagagatg agcttaaatg atctggctca agcagtgcaa
487741 ggtgaaagtg gaataggcta gtgttataga tgagtattga caacaagttg tttgttactg
487801 aagaggatga ggaagacagg acgcaggacc gtgctgatgt tgaggatgaa tctaacgaca
487861 ttgatatgat agcggatgag aacggaacaa acagcgctat agctaatgag caagaggaaa
487921 aatccgaaga agtaaaagct gaagatgata ctggtgaaga agaagaggat gacccagtga
487981 tcgaagagtt tccattgaag atctccggag aagaggagtc actgcacgtg tttcagtatg
488041 ctaatagacc aaggctagta ggacgcaaac ctgctgagca tccgtttatc tctgcagcaa
488101 gatataaacc caagtcgcac ctatgggaaa tagatattcc tttggatgag caggccttct
488161 ataacaagga taaggctgag agcgaatgga atggggttaa tgtccaaaca ttaaaaggcg
488221 tgggtgtgga aaacaatggc caatatgcag catttgtcaa agatatgcag gtttatttgg
488281 tacctattga gagggtagca caattgaagc catttttcaa atatatcgac gacgcaaatg
488341 taacaagaaa gcaagaggac gccagaagga accctaatcc ttcatcacaa cgcgctcaag
488401 tggttaccat gtctgtaaag agcgtcaacg acccttcgca aaacagactc actggctccc
488461 tgctggcaca taaagtcgcc gatgaagagg ctaatattga attgacctgg gcagaaggca
488521 cgtttgaaca gttcaaagat actatcgtga aagaagctga agataaaact ttagtagcct
488581 tagagaaaca agaagactat atagataatc tagtttgaag tacataatgc atcatgaaga
488641 aagaacagca tcagacatca gtttcacata aaggatgctc ttgcgctttt tctccttttc
488701 tattaagtca ttgcgtgcat atattatgtg atttttttta atcataccac atcttgatta
488761 actcttctga aacggcactt ggagtgagga cccctaaatc tgtaatcaat gcagtaatgt
488821 attcttgggc ggtatagtcg atcgtgggcc cacgcaatgc atcttctaga tcgtccgtac
488881 gacgtgtgaa atccaaagga gggccggcca taggtagatc atctgaagac aatggaaaca
488941 tacgaacaaa tttgtgactt tcagtgacca catagaatgg ttttcttgca ttatgtgcta
489001 aaacacccac tgaataggta cccacgagat ttataatacc acctgattca gcaacaccct
489061 cagcaccaac gaacactttg tcaaccttat cgattaccgc tccaaccgcg ctatcgacaa
489121 taagagtcac gggtatgccc ttttgttcaa gtaaagtata tagctggttc ccttgtttgc
489181 taggtcttga ttctgtcacc acacatctga acctaataaa cttatttgct gcatgattta
489241 ataaagaaaa tactgctctc gaataaccat gtaccaagat gatatcatca tcagctatga
489301 aatccacccc tatttctgca atcttgttac gcgatttttt ggctctcgat acaaaaagct
489361 ggccattttc aatcaaatgt tgtttacagt tttcccaatc accgtataaa tgaagatttc
489421 ttaagacaaa tctcatgaaa atatcacaac cggctctcag ggaaactgag ttcggaatgg
489481 atttaataag ttcttccgtg gagcttttta ttgtattaat catttctgcc gctgtttctg
489541 gtgtttttat tcttaatagc gtgaccaatg cttcaatggc agcaatcggc attgtcatct
489601 cagtatcttc ttctaaaaac cttagataag tttctgtaat attaaactcc gacatccttc
489661 ctctcgattt ctggtatacg taggactttt aaaattcttt ctatcaatta ctatgaagaa
489721 atctatgatt aatgatggct ttgtcactat ttgagcagta tgattctcat tttacaccat
489781 aaacttcacc aattttttca tttttttttc atttttcttc cggatgaaat ttatctattg
489841 taaaaaaaaa aaaacattat gctatgtaga aagctttaaa tatggcgaca atgttgctgt
489901 gttgtatcaa attccctgga tagagtcgtg cactcttaat gtggcgaaaa tgatggcatt
489961 gcctccttat tctttctcat aaaaggtatt actaatcgtt atctattacc aacataagat
490021 atagctagca attcttgtaa gcacaattac atatgtttag ttttattttg aaaagcaata
490081 caagcgcaaa ttgtttggtc tgttttggag agatcaccat gtagctggca ctgctgcaga
490141 ttgtcatgta gtaaacatac tagtaaaata ttcttaaaat aatttgatca gatcagtttt
490201 gttcttctat ctcctatgtc ataacatacc gctcattttt actatcgtta tgtttttcat
490261 tcagaaattt tatttttctt taggtcttga gtatcgactt ccacaacatt ggatgactgt
490321 acctcacgat ttgtgtattc tatttatgca gtatgtaata acatattagt gtcacgaccg
490381 ctagccaata tacgatagtg gatctttatt ccaaaaaata cttatctaac atgtttaaca
490441 acagatcaga tactaaaact ttttgtctga ataagaatta actaccatct atgcactagc
490501 acacaaatta gcagtatgtt ctcatacaca gtgtaagaag atgacattaa gaatgagaaa
490561 cggttattaa atataataga agctgaaatg caagcattga taacgtaaca agataaagaa
490621 taagcatata aagtaaaaaa acgagacaat aacattacta ttcatgaata ccgattcctt
490681 cttccgcatt tctaatatcc tcgaagagaa cttttagtat attgtgtatc atagccttca
490741 acaataatgg aacaccagta attatcatat tattcaaaca tttctcaatg atagctttta
490801 ttcacaatgg aacccaacaa ttatttcaaa attcacacat ttcttacttc ttagagcagg
490861 attagttggg tctggtaatt tgaactacta tattaggtaa aaaatcatgc aataaatagt
490921 gctgatactt agggttctca atttttaatg tctcttaata attcttgttc ctcgtggccc
490981 aatggtcacg gcgtctggct acgaaccaga agattccagg ttcaagtcct ggcggggaag
491041 aattttttta cttttataat tttcttatta tcttttcagt tattgagtaa aaatattata
491101 atattggaaa tgctacgttg ccagtcctgg tgccgtacaa tgccgtatta ttttagcaat
491161 tcgtcatcag gtttccgagg cattgttaca ccgtttggga aaaataagat gtatgcacaa
491221 tggtgtatct aaattcaaca taaaaataaa aaaaacaaaa tgacaaacgg caataaagag
491281 acattgtgtg caaagaaagg gcatatatat caagtagtat aagtagtaaa gtacagttaa
491341 cagatcaatt ggcctcgagg aatatgagtt ttttatgggg gtctacaaag tccaagaaag
491401 gcaagaataa aaaggctgca ggttctcttc cgtcaggtgt tgttccacag caacgtgtga
491461 aaccaacacg taaaaacgtt cctatagatt atccaagaac tttggaaaaa gtacatggtg
491521 aaagtttaat ctttaggacg tcccttttaa gtgaattggt gagcactggt aaatctggta
491581 ttggtcctcc agacttgatt cattgtacag agttagataa atttcacgat gagaaaatag
491641 gtgaattctt ttacatcacg gggatcgacg cctcgagcgt ctctatgcca attgcatttt
491701 tgaagctgat aaaatggaat gatggtaaga aactaaaatc agcatctttg aagaacgacg
491761 acatcacaac ctactgcact ttcaatatct ttcaaaaatt ggacattaga ttaagatatg
491821 aatctgaaga tgtttatcaa gttaatatcg ttgactgttt aaatggcaac aatgaaatac
491881 cgttgagtga tcttatttgg gaagaaactt tcgttagctg ttgcataaga agcgtaatta
491941 ttaattcaga ttttgaaaga aaaatacctg ggctagtgga attaccattt gtttttgaga
492001 acagatgcgc gagtgattat aaaagggtga tagattcgtt atgcaaattt ttgccaagat
492061 ttttagaatg tggttgggat tctacaaaga gcgtctatgc aacgatactg aataactacc
492121 taactgaatc attattagta tttctgtcta taactccaga attcataaca gactatgcga
492181 tccaggtttt agacaacttg atgacgaatg acccgtcaaa ttctagatat tacgctattg
492241 taattatttc tatcatggag cgaagtaatg accgcgatgt agaaatgatc aaacggatac
492301 acgagatatt agacctatta ctacccgtac tgtatggatt gccatccgat gaaccttaca
492361 tttctgattt gatcaattgc atcaccgatg tattaagcat ccaagcaagg tttctattga
492421 acaataacga ctatgaactt tctttatcca tttccacatt ggccacgaat ttatcttctg
492481 ataattttga atcttggtat ctgttatcta aaggctatat tttttcacaa cagtatgata
492541 aggcactgct ctcaatcaat tcgatgccct gtttagcgga atatgatatc gttaaacaag
492601 cccagattaa cgcttttaag ttttatatga actactacaa ggcaccacta tgtcatagca
492661 gagaacactg taccatgaca tcacacgagt taaatcacct catgaatatt atgcattatg
492721 aaaatgagtt ggagttgaag acaataatat ttggacgcac tgtaatgccc aatgaatcta
492781 agtatggatg tattgaagag atatggaata aatcctgtct tgaattagga cctatttgtg
492841 gaccacagag tgacaatctc ataaactttg tatctcagca ggaggtaaat acagtaggag
492901 atatgctgtt actaaaacga agcaaagaaa ccagacaaga gagttggttt ataaagcaag
492961 tacgtcttct gttgatggaa ttagtcgcta gaatcggctg gaacgcctta cttcagctaa
493021 gatctgacgt tttcgttatg gagagtaaat tcaaaatgat agaatcttcg gacaagctgt
493081 ccacagaatt acgccagaag aggctctgtc agagatggtt tgatgctatg tttctggacg
493141 tttacgaaga tttaagtatt agcacttcat ctcaagaaaa taaggctacg gcgaaataca
493201 gcgggttgga atgggaacta cttggcttaa ctctgcttcg agtgagtgac ttacccgatg
493261 cagtagcgtg tctacgaact agtattttgg caaggtttga ccctattagt tgtcaccatc
493321 tgttgaactt ttatttaacc atggatttta atgatgagtt tatgagaagg tttgacgtcg
493381 atatcatttt agatctatta gtgaaattga tctcctttcg gatacgattc tatgatagat
493441 ttcagatatt ttcccttcaa gtactaagga aactagaggg acagctgggc tccgaaatta
493501 ttaagaataa aataattaat tctccttacg ggcaagctgg catcacttcg gtgatagatt
493561 atatgcttga atgcctctct aaaaatagga atgaagcctg cctagcctat gaacgccctc
493621 ttccagatct tccttccact atcaaacctc tggcagacta actgatcaaa ttgatttaat
493681 gaatctatat atatatactg tgtgtgtgtg tctgtattct taatggacaa atttacggcg
493741 ataatgctaa tactttagcg cgggtaatat cctaatagta atttttcaac gatttgacag
493801 agtaaaaaat gaccagcgta aaaataacat caatacgtca agggtatact agaccctttt
493861 cagctctttc cttgtccatt cgaagacata tcaaagataa gaaaggtgtt ggatatttac
493921 tattgtaatt tcacctttta tttctttttt tttgacgggc aattgtttgt tcgtaataga
493981 ttttctatca agtcaagaat tttttattct tgcaaaggcc ggctcacgaa taaagagttg
494041 catttgcctt gcaattcgta cggttaattg tcattttttc tatttgtatt ataagatacg
494101 aagggtacct cattgaagta ttttcacctt tagcattttc tttatcatct tttgttttgt
494161 ttgttcattt actttagcgt ttagttgata agtcctgtta tcctcttctt ttatttcatt
494221 tcttcattta cttaactgcg agaagattat aatagcatgt caggttcttt ctggaagttt
494281 ggtcaggatt actcgataga gtcaccggtt tctaagattc taaatagtgc ctttattaaa
494341 atcaataagg accaagatga cgacgtacct accggcacat gtgaagaaaa tattgctgat
494401 gacgaagata actcttcaca tgactacgct gcttctgaag ataatgtagt taacgagaac
494461 gaagagaagg aagaagaaaa tactctgccc actacagaat cggaatatga aaattataga
494521 cctaatttgg acgtcttaga cgatttgctg gatgatgacg aactgtatac ggaattaatg
494581 tgttcaaatt tcaagctact aatattcttg aagtatcctg atgttttatc aaaattgata
494641 gaatatgtta ccaacgagaa gattctcgac gaagaaacag atagcgctaa aaagccagag
494701 attattgaag gtgtaaacga tcatcctatt ttgatagaaa gagacagaaa ggataaaaag
494761 gaggacgctg aagaaggagg cgactcagaa gaaactacaa atgatagcga tcatgactct
494821 ggggacgaaa gaagtgttga ttctgaagag acaagcatta ctttgccacc ggaatctgag
494881 gaacaagtgg agactagaag ggcaaggata gctgctgaaa ttttatcggc tgatgtatgg
494941 cctatatccg cagcaataat gcaaaataag gatcttcttg gtagattgtg gtcgatacta
495001 gatcacccag ctcccttacc gataccagct tccacctact tcatgaaaat aaatgaaaga
495061 cttctcgata tggatataac ggggatgtta gagtttatat taagccgaga cagcttggtt
495121 gcaaggttct tgacacatgt tgacaatccg tctttgatgg acttcctttt gaaagttatc
495181 tcgacggata aacctgactc tcccacgggt gtcataaaga tactaaaatc acaggaatta
495241 atacctaaac ttttagatca tcttaatcca gaatacggta tttccactca gtctgcggca
495301 ggcgatttta ttaaggcatt cgtcacgtta agcactaact caagcaatga acttgcttcg
495361 ggaataggtc ctaatgaatt gacaaggcaa ttagtatcag aagaaatgat agaaaagttg
495421 attaagataa tgctaaaggg cggtacatcc ttaagtaatg gtgttggaat tatcatagag
495481 ttgatcagga agaataactc agattatgat ttcatccaac tagtctacac taccctagaa
495541 agtcaccctc ccactgatcg agatccaatt cacttgatac atttagtcaa actttttgct
495601 aagcatatgc ctgattttgc tgatatgctg gataaaacca agttgccact aatggaaatg
495661 ccattcggta atattgaacc tctgggattt gagaggttta aaatctgtga acttattgca
495721 gaactattgc actgttctaa tatgacgctg ctaaatgagc ccaatggtga gatgattgcc
495781 caagaacgtg atatagaaag ggccaaagaa ttagaaactt caaccgaaaa ggaaaatata
495841 acagctattg tggacaataa atcatcatat tatgataagg attgcgtaga gaaggatatc
495901 acagaaaatt taggcgctct tcaaataaat aatcaaggaa gtgaagaaga tgaattaaat
495961 gatactgggg tatcaagtgt aaaactagat gtgaaatcag acgcaaaggt agttgagggg
496021 ctagaaaatg atgcttctgg agtagagttg tatgatgaaa ccttgtctga cacagaatcc
496081 gtgagagaat gcctaaggga aaaaccgcta gttggagaca ggctgaagat tgctctagaa
496141 gacactaaga tactgattag tatccttgat atgttcactg agttcccttg gaataatttt
496201 ttgcataatg taatttttga tattgcccag caaatattca atggtcccct caaaactggt
496261 tataataggt tcctcttgaa agattatttg gttgatgcat acctaactaa aaagatagta
496321 gatgcggata aggcatgtca agactatgaa aaaaagaccg gtttacgtta tggttatatg
496381 ggtcatttga cattagttgc cgaagaaata tcgaagttca aagagtatat tgatgaaatg
496441 aagctaactt tttgcaatac cgctgtttca gatcgacttg aggaaccatt ttggaaagaa
496501 tatagtgaaa cgatcttggc tgatacaaga gagaagtata acaccgtttt gggagatttt
496561 ggcaatgacc aagaaagcga tgacgatgtt attaggaatt ctgattctga ggatataatt
496621 ggtgatacag agggcaacga aaactacgga aatggagaaa acgatgaact tcttagtaac
496681 gggcatgatt ctgggaacat ggatttatat tataacttca ataataacga gaatgaagaa
496741 aatgaagaag attacgcaga gtatagtgat gtggataata aaaattacta taataacgtc
496801 gagactaacg acgatgatta tgatagtgat gatggtaaat ccaaaagtgc cgaatcagag
496861 tttaccgata aaatatctga acatagggat ggcaatagtc tctataatga ggacaatgat
496921 gaaaacggga gtgacaaatg gacatcgggt acttcattgt tccctccaga ccattttcct
496981 agtaggtcac aaccttcaga tcctaaactg caagaccaga atatttttca ccatcagttt
497041 gactttgaag gtgttggcga tgacgatgac tatatggatc ctaatgatga tggccagtca
497101 tatgccagac ctggtaatcc attgtatact accccgaaaa caccaccaag accgaagact
497161 attcttttca attctttatc cgcattggat aataatggcg aagacgaaga agtggcacta
497221 ggcaccagtg ttgatgatcg aatggataac gagatatcaa gcgatgaaga agactccgaa
497281 gatgaagatg aagagaatga tatgggcaat gaggagggct actcattata taggtcaaga
497341 agtaaagaag ctttctgaac taaaacattc acattgtcac attttcaccc tttattcatc
497401 aattttttat tgctccactt ttttcgcata taggtcattt ataattcatc aaatatatac
497461 ttttttaatt gaggcttgta atttaatatt aaccgaatat aatcttataa agaataatga
497521 atattcactt ttgaatatac ttaagtttat ataggtgtaa gaaggaaatg tccatgttta
497581 tttcagtagt ttttttctgt aatccgcaaa gcttaatttc tttttcgaat gcagttgtga
497641 ggacgaaaaa tctgataagt gcattatact ttctggagtg gattctcgcc ttgaattaac
497701 cgaagcttct gtcatgattt cttttgtttt tgcttgactg tgttgtgctt cctttgacag
497761 ttctttattg aaatttgaaa gagaaggggt tctacttaat ttatgttcat tctttgattg
497821 actctcttcg acatcgtttg cagtttgcct tgacgtcttg tttattggta aaagaactgg
497881 aattggtaat tcttcaatat tggtaatgtg tgattcgtca taatctgtgc tcttcgtaat
497941 tattaaaggt ttttctgaag tttcattttt tttgggaaca gaaatattag aagaatgttg
498001 tgcaaataag gcgaatttga agggttttgc aatatcatca ggattatttg tactatcaat
498061 agtattcttt tgaggaattt ttggaccatt atttcgatta aggaattttt gtcgataaaa
498121 attattcaaa agtattggag ctctttctat agtattttga gccttttctt ctagcctatg
498181 caaaattggt ggctcacgtc tctttttgca attatattgg ttgagaattt catttaattt
498241 atatctgttg ttcatttttc ctctggattt cacagattta taaagacttt gcgcgtatct
498301 cttcactttc aataaataac aatctttaga attatttcca cagccgcatt cgccgttact
498361 caaaattgtt tctaccgaat ttatcagccc atacctttca aggtcatcta aagagtctat
498421 tgtcatgccc tttattaatt ttaatatagg atgttttgaa tcccactgcc atttgatgta
498481 taactcctca tcctctgaaa tatctctcaa agctcttaaa acaaatttta ttctacttga
498541 ttttcttcca ctgcttttgt cattcctatt gtctgtatct tgcagtttta tagttactaa
498601 ttcaacattc ggctggcaac ttcttctcaa atacctagtt gaattgcctg ataagcgtgc
498661 atctatatat atcggccaat gggaatggaa aatgaccctt cttttagctg taccccatat
498721 cctgtaatgg tttcgtgggt cagtgagata atttttatag aagtccaatt cgcctaaaat
498781 ttcttgaatg aaatcacctt ttatgcagtc ctttttgaga taaactccta atttcgtgaa
498841 gcctgggtaa gtcctggaat atgcaatgtc agcatacggt ttgacttcaa ttgacacaga
498901 tttaaaggtc ttatgaggat attgtatgac ccaattatca tccatatgtt tatttaagaa
498961 cggttcgatc agatcacttt taaacacatt gtctttcaag ggcaagtata ttgcaccata
499021 tgcgtctttt gcactcagga aatgctcttt tttcttgggc atagaagtca atccatcgga
499081 agaattgaca gaagcgcttt cgtttttgga gtctatacta ttatttgatg ggtttctttt
499141 ccttcttttg tccctgtggt tagtattgtc ctgatccgtt gaaaagctat cgccaacgtc
499201 actaatagtt gtactcgatg ctctgtcccg accgttattc ttattactag cactattgtt
499261 tgatgaagaa ggttctactg tttttacgtt tatgcgttcc tgctgtattt tcctagccaa
499321 gttaatgtct acctctcttg gatcacatga gttgcaaagg taatcatcag gtgccatccc
499381 aatatctttg atgccatagc aaatagcatg ctgccatctg ttgcagtggt cacattggat
499441 agtgaatcca tcatcatcat ttaaatcaca tatacatgta attatacccg cgtcaggatc
499501 gactatatac gaatcaggta ccggccattg aggttgcttt tgaggttgat tttcggtctc
499561 ttcttttgct gccgtggatg ttgctgcttc tgccgccgat tgctcagtag ctttctttaa
499621 aggtaaagaa actgtggatg ctgtagccag tgctgctgct gccatttcta ttgctccttt
499681 tttttctctc tcatgagact catcatgctc aatagtatct gttttagagc ctatttttga
499741 agcttcttca gctctttttt tcccttttga aaacaataac aatgtggatg catcatctag
499801 gagcgactgc tctttggaat taggtactga catgattcag ttctcgtatt ttgtgaagta
499861 cgatctaaaa ctgttgtata tacgctttaa atcatgttta ctagaaaggt cctttattac
499921 tactttctgt atatagcatg tcgttgataa tgatatgcat ctatcatgac atagtaagat
499981 gaatgagttg gttgaacaat ttccagggaa acaaaggact agtttcatgt ctttaatgtt
500041 tttttacgaa taatatacca tgctataaaa gtattataat aaaaggtatc gactacctgt
500101 aatctagaat gataatttca tacaacgatc acttccaacg gttaaataat taccaataga
500161 ccttactaga atattaaact taacaggttt aaattttgtt gaaataactg caaaaagcca
500221 gaaagaaaca gatttgcact ataatttttc gattgccact acttagtcaa cggatttatc
500281 aatgtcatat ttgccgactt attccaacga cttgccagca ggcccgcaag gccagaggag
500341 gcgtaataat ggtaatgaaa acgatgcaag acaaggctac ggtcagcaat ctgtgccgat
500401 ggtaatcagg aggcttttca aaacgccaaa gaatttagat ctcgagacag ccagctggga
500461 aatgttccat ttgattttcc atccaagaaa agcttataga tcaatatatt atcagcgaca
500521 gacgaaaaat cagtgggcga gagatgatcc ttcctttttc atcttccaaa tagccttaat
500581 ttcactcagt tctattattt ggtcgattta taattcaggt ttcaacaacg acagtgatat
500641 gggggccttg agcattatag gtcatttttt caaaagtttg gtaatgatgg tgattttaga
500701 ttttttcata tttggattta ttatggcaac tattttttac cttttgttga ataggtcaca
500761 ttttaaattc aaatcgagcc aaaatagtgt ggtagagtgg gcttattgtt tcgacgttca
500821 ttgtaattca tttttaatca tcctactgtg cctatacttc attcagtttt tactactgcc
500881 cataattaat ttacaaaact ggatttcctt actcattggt aattcgttat attgttttgc
500941 tattggccat tactttattt taacctttta tggatacaac cagttgccat tcttgaaaaa
501001 tttgaacttt atacttttac caacattagg attatcgata atctatttaa tcagtttatt
501061 tggcatcgac ttatccaaga aattaagctt ttacaattat taagcaattg aacacggaaa
501121 tagaaaaaat ttggttcttt aagataaagc acataaatta cataatgata ttattattat
501181 atatatttga agtataaaaa tgcaatgagt aataagagca ataatgacac tatggaccaa
501241 aagaatgcat aatgaaaact gtttatgtat cagcgtcgaa tgcttataac agataaaagg
501301 aaaatacagg taatggtgtg ttcctggtcg tttttatatt cccttaattg tagatttcca
501361 ttggagaaag tctatccgag ttaaaaatcc aatttctact ctcaacttct ttagctaacc
501421 attcggttgg gaaaatgacc aaatgaccgt ggatcctttc caagattctc tgcgccgtat
501481 gtttgtcaaa aaccttttga ttgaatccat aaagcaaact accggataac ttcattctca
501541 attcagcggc ttttctcatt ttttcctttt ccctatcctt atctacaaca tttgtagtag
501601 tagaattaat attttcagcc tctaagtcaa tcaacttttc ctggtttatt tgaaattctt
501661 gttctaattc agtaaattct ccatattctt tccaattttg tacagcatta tcgggttgac
501721 aatgaaacac taatttatag agtaatgtat ttctcaaggc tatagtgaac catagccctt
501781 cagaaaacga agaaataaga ggatcctcga aggaatacgg gtcaatgaag ttgagtttca
501841 ataactcttc tttttttgcg tcatcaattt caccactgtt aaagttagtg atcttaggaa
501901 ttatctgaga aagtagatcg tccagtgaac catcatctag ttcttgattt ttcaaaatat
501961 cttcgtgcaa tctatgatat tcatcgcctt cgatatcttg gtcgacatta gtgctttctc
502021 cttcattgct cttttcgttt aatggcagac tattagaccc atttctggta ctttctgtgc
502081 ttgaacttaa atgtcttctc atatctttga ttttcttcaa tctctgtgtt tttctttcgt
502141 cgagtttatg agataaatat tgcaagtagc atatcctttt gagcatactc catttgtttc
502201 tattggtaac agttttatcc gtgagataca tttctagatc tttctcattg ggcaaataat
502261 ttgaaaatcc ttctggaatt tctgatttta tcatttcttt atcgtcaaga actttcgagg
502321 ccaatgagtt caatgcccac tcctttagct gttcagttgc atcggccttg aattttttgt
502381 tggattcctt tttccaacaa tcgggaccgt agccatcaac ctctttttta tgttcatcat
502441 tctttcttaa tcttggatca gtacttaaga ctttgtggtc tcgtataccg acattttcaa
502501 ttcctgccct gtggttgaat gttagcccta aagatgcaaa attatgtttg ggcagaggcg
502561 ttctcttacg tgatgattta ccgtagtcca cagaattgaa gaatttttca taaacgtttt
502621 catcttctct tcccacttct ttttcattta tgccacactg agtgcttcca tcatcaacac
502681 tgtttccatg accactcttc cattgagggc taaatttaca accaaatatt tcacgataac
502741 ctagctcaat catagcggaa tcgatcattt ctcgatcgct ccaattgtta ccactatctc
502801 cctccttact tagggtatga agtttttcat aattctttgc agcaaacttt tcaaaccttt
502861 caaatttctt ttcaacaaac tcaacaagat ctacatcaca acctaaatgt tccctcatta
502921 atcgctgcct taattcccaa ggaaattttc ccgcgtagta atcgtcacca ttcattttgg
502981 tctttatcaa gtcggtgtct ctaataagaa ttgccacctc actatctcta ttacccagtt
503041 gtgatctttc gttaatatta gcagacccta taatacatct tctgtcatca gcaatcagaa
503101 ttttagcatg aacgtagagc tgctcggtga ttaatctttc attaggcgca aaagtcgacc
503161 attttcttag tgaaaagaac tgaatatatt gagctgggtc aatatttagt ttcttcagtt
503221 tactaaatgt agaatgttca cctcttgaaa ttgattgata ttggaattgc ataattaaac
503281 gaagacttga ggcttctgca gtatctactg gagaatcgaa tcctggcatt agtgggataa
503341 gaataaaggc tttccaaggt tttttctcct gattagcttt gactatccta tcaacgagag
503401 catcaccaat tttattcaaa acgcaagtcc cgttccagac agttgatgta atgaagaatt
503461 gattctcaat ataaataaag tgttcacttt gttcaattaa cttcaggtaa gcattttgaa
503521 ttgagcattc cgtttccttt agcccaagag accagttccc agcacttcta agtatttgag
503581 tttcacaagt cgatttttcg cgtagaattt cgaacatcgg caaactcttc aattcttcag
503641 cagttaaatc tgaaggcggg gttagtaatg gagttaacct actaggtctc ttagctctca
503701 ataagtaatt ccatctttga acaaaatgtc gggctaagtc tcttgctggc tcacccaaag
503761 tcatcatttg cacatcatgc catggcatcc tcggaatgac ttttctatca tacattgatt
503821 cgaatggttt atctaaatca tgaaaatcag caattctggc atttgaataa tccttaccag
503881 gaaaattttg atctaataaa gattctgcat catctcgtag aacgtgttca aaagtatcat
503941 atctaccata acataaatct gtaccaccaa taaatgcaaa tgtttcatca ataacgacaa
504001 acttctcgtg gtgtgcccaa aaatatgtat tttgtagcca ttgattggga gaccttatga
504061 tatgtatatt tggatgtaaa tttagcatag aatgcttggt ccaaagacta tctgtcccaa
504121 caatattccc cacattccta taaatcacaa taaaaatttt gatacctttt tctgcacaac
504181 ttttcagcat acgatcaatt ctaaatccct ggttgccttt caccggacgt cgcaagtata
504241 attcagggga tagccaccaa tcatggatat atatgacatc ctttgccatt aagagggcct
504301 cgcttaacga ccaaaaataa tcacgcccat ctaccaaaaa tttgcaaaac gaatttgttc
504361 ttacaggtgc gaaactacca aatctatttg gtttcgacca aggtgttgag gtagacattt
504421 tgataattga actcatccat tgctttaacg aactctctga tttgcaaata attttcagtt
504481 tcctttcact gttttctagg gtcaataata atagttttga agatatattg gacttctttt
504541 ggtgtgtttt cgattttcca ttcttgtcta ggatattatt ggcatcattt tcaataccga
504601 actcttctag ttcgtcattt atttctaaat tgggatcatg aatgatccag ttgatctcgt
504661 tttcgttatc aagtatgtta ttcttgttcc cagaaaatct aaccttaaat ttccaatcta
504721 ttaagaatac gtctaaagga gttgtcgaag aaagatccga cacgtaagtt aggtaagaat
504781 ttcttaccag gaaccatttg gtagtatgtc tgtcgatcat gtctttaaac gcatgtttac
504841 caaaatgaga aactctccaa ccttgggcct tggcagtaga tctaattact aaatacccct
504901 gtttgccctg gaacccactt tcacgactta ataaattgcc taagggagat aattcgtaaa
504961 attcaaacaa tctatttgca tgaggtctca aacataatgc aatgttcagt agtctcaaat
505021 acctttctag cctcaaatgt atcggttggg agaaatcgtc aggttcgtca attaagtctt
505081 gtaaatgttt cattttgacg ttatctatat taaactcaga tatttcagaa gatgataaag
505141 tttctaacga tgtaatgttg ctgccattat cgttattgtt attttccgat gtatgaggag
505201 ctgaggctgc agaggatggt ttattttctg cttttttctc cattacattt ctttctttaa
505261 ccatttcttt ataatggggg aaatgcggaa gttgtaacga atgatatctg ttgttatcac
505321 tataaagctt gcttatagtg agttgttgga acgcgacgat tttcaatttg tgatgtagtg
505381 atttgatatc tttataactt cttataatag accatttgag cctgtcttca tcaatcccat
505441 attccaagtg tattctaaat aaagagtttt cgttcctgct atacataaat tccgccacat
505501 tcgaagaaat gcttataatg ctggagctcc ttggaataga gggtctccta tcagaattct
505561 cgccagtatt gttgttgttg ttaccacgat ggttatggtt gctattggta atatccaaaa
505621 tgttgttgtc atttttcaag ggagacactc ttacatctag tttagctaat agcagaggag
505681 cccttctctt cccatgttcg tctctcagaa attgcgtgct tgcgaacaat gaggccgggc
505741 atcctgccaa taacgaatct aataaatcag aggctagtct ttgtgtgtac aaatcttctt
505801 cgtttacttg ttgatgctgg tgctggttat gacgatggcc gcttccagcc ggtgtaggag
505861 aatttacgct ggatttcagt ctaccaatag cagagatttt cttaaaagcg tggccaaact
505921 ctttcttcca gccattgaac tgctgttggg tgtaagctac agaagaagaa cgcctttgag
505981 gggctctttc ttcctctctt ttagaattcc gcttagaatg aacattattg ttactgctat
506041 ggagattgtt gtagagccgg tgcatatttt cctcatcaga acctcgacga ggatcatgtt
506101 cattagagtg cataatatgg tctaatgagt ggttcggtga cacatcactc aggtttctat
506161 ctacaaagga tttgggcaat gcatgcttcc tctccgcctc cttgccgttg ggagttcttc
506221 gtttttctct ttgtaaactg ctagtcagat tgccattctc aggtaattgc cgcaatactt
506281 cttggttttc taactcatct ggtctcgaat ttactctatc tacttcttca gtcaccgatc
506341 tatctgcctg aggtggagcg aagtgagttc cagacgctgt tgacacgtta gacatcaccc
506401 ttgtttatct atcctacctt ttcttcttgc gtacgtgcct ctcaatgcgt cgtgtgaatt
506461 atcagtgacc ggtcgtgcct ataatgtcct gctaatttcc cactaaatct ttccccatgg
506521 cgtattcatc gttatgtttg tgtcttttgt tcaacccaaa gggctgtagc aatcttcacc
506581 cgtttgtcgt tgataacgag tttccacctt atcacttatc actagtgcta atcaaacagc
506641 aaagaatgct tgatagaaac cgatcctggg cttatctcgc tgcattgtgg cggcatccct
506701 ggactgtaat cagcaagtgt tgcttagtat atatatacat ccagcgtcag cttgaatttg
506761 gatacagtta ctgttttttc gattttctct tggttattct ttctgagaca gtagtaattt
506821 tgtattactg agcgggatat tgtttatctg ccgtcatact atattacatt atattatatc
506881 atattatata taagagaatg gtgcttagtg attcgttgaa gctgccctcg cctacacttt
506941 cagctgctgc tggagtggat gattgtgacg gagaggacca ccccacgtgc cagaattgtt
507001 tcactgtcaa aacgccccta tggagaagag atgaacacgg tactgttctc tgtaatgcat
507061 gtggcctctt cctgaagttg cacggggaac caaggcctat cagcttgaag acggacacca
507121 ttaagtcaag aaataggaaa aagctgaata acaacaatgt gaacactaat gccaataccc
507181 attctaacga cccaaataaa atattcaaga gaaagaagag actgcttaca actggtggtg
507241 gttcattacc tacgaataat ccgaaggttt ctattctgga aaagtttatg gtgagcgggt
507301 ccattaagcc actgttaaaa ccaaaggaaa ccgttcccaa cacaaaggag tgctccacgc
507361 agcggggaaa attttctttg gacccctgcg aacctagtgg gaaaaactac ctctatcaga
507421 tcaacggttc agatatatac acgtcaaata tagagctgac aaggctgcct aatttgtcaa
507481 cattattaga accctcacct ttttcagatt ccgctgtacc agaaatagaa ctaacttgga
507541 agctacataa tgaggaggag gtaatcaaat tgaagaccaa gataagcgaa ttggagttgg
507601 tgacagacct atacaaaaag cacatattcc aactgaacga aaaatgcaag caactggaag
507661 tggaactaca ctccagagct tcagtacaat ctcacccaca acattaagaa aggatgtagc
507721 gttcatgaca gtataaatat aacaggatat agtatataaa atttaatatg atttagtgac
507781 acttattttt acgcgaacgg gtaacacact gccatttatc tggtgctgga aaattgcccc
507841 taaagaaatg ataagaatga aaacgaatca atgtgaaagc agtttgatga gatgtgagct
507901 actttgaaag tataggaagt cagacatcgc actgagaaat gtcacgtaat tctgcagcag
507961 gtttggaaaa cactcttttc caactaaagt ttacatcaaa acaattacaa aagcaagcca
508021 ataaagcctc aaaggaagaa aaacaggaaa ctaataagct caaacgtgct cttaatgaaa
508081 atgaagatat atctcgtata tatgcatcca atgctataag aaagaaaaat gaaagattac
508141 aactgttgaa gttggcatca cgggtggatt cggtcgcatc aagggtacaa accgccgtca
508201 cgatgaggca ggtgtcagca tcaatggggc aagtttgcaa aggcatggat aaggcgttac
508261 agaatatgaa cctccaacag ataaccatga taatggacaa gttcgaacag caattcgaag
508321 atttggacac cagtgttaac gtatatgaag atatgggtgt gaattcggat gccatgctgg
508381 tggacaacga taaggtggat gaactaatga gcaaagttgc tgacgaaaat ggcatggaat
508441 tgaagcaaag tgcaaaactg gacaatgttc cggagataaa ggcgaaagag gttaatgttg
508501 acgacgaaaa ggaagacaaa cttgcacaaa gactaagagc attgaggggc tgaaaaaaca
508561 tgctaacagg tcatgcattt ttagttcatc attacgtttc cagctatgtt atgtatgtat
508621 gaccacatat gctgtacata aattgtatac taaaatcaat aaaaaaagta taactctttt
508681 tatatataat ctttttcctt cctaaagtgt ccatacattg atgtctccat cgttgtgccc
508741 attgatcaga aatccgtctt tatacttgac aatagcaatt cttctgctca gctcatcccc
508801 atctagtgaa tgcggtggtt caggagtcat ccaatgctca tcgcgctcca tgttaaagac
508861 attaacccct ccctcgtttg cgccaacagt gattaattta ccatcgaaat ctaaggacga
508921 tactggtaaa tcgtaagcaa tcacgtcaag aattgagctt gtcctcaaat cccaaatcct
508981 tacgctattg tccatcgagc ctgttaccaa tttttcggaa tcaaacttca aacttgtaat
509041 tccatcggta tggccttcta gtaatctcac cggtttgcca actcttagat cccatagtcg
509101 cacaatgcca tcttttgttc ctgttgctaa tgcagagttg taacattgga gggctcctat
509161 cattggtgct tctgtgccaa gtaaacatgc accattgttt aatgaacgtg caggcatttt
509221 aatgtcgcta tgtgtaggtg tgaagataag gtcaagttgc tgaatacatt tgcccgtcgt
509281 taaatcccag tggaatattt ttttgtccct agatccgcta accaaagctt cagaatcaaa
509341 agacagggct gtgatttcgt ctttatgtaa ctcaaaatta tggatacatg gtgtaacaat
509401 ttcttctgtc ttctccttca atggactatg gtccaaatat atttctctac tcagatttaa
509461 gtcccataac ttcagagtgg catccttact tccagtaatc aacatattgt aatttttctt
509521 atctatttgc atgcaattaa cagtagcaag gtgaccaggc agctctccaa cttgtatccc
509581 atggttcaaa tcccacactt ttactatacg atcttggtag cttgatgagc acaaggttcc
509641 ccatggtgta tcaaagtcta atgcggttat gctgtttcca tgttcgccat ggggtattgt
509701 cattctgaaa gccgtggtat ttcggctata tgtttctgag ataatttgcc tgtttttatc
509761 gtggcttttt tcatggggca tcttgtaaaa atcttttaat ctcgtatcct tactttcaac
509821 atcacataac gacgatatgg cttcttcatt ttgcgtgaag gacgacgctt cagatgatct
509881 ttcttcttcc atttgcttcc gtaagctctg ttcacgatca gcttccaaat tgtattcctc
509941 gataaaattt attctatcct ttatcagtgt tacatcattc tcaagattgg tagacttact
510001 atcaatgtgc ttaacccttt ccaggatttt taatttcctg gattctagtt cgttgatcat
510061 ggaatctaat ctggtcaact catccatctc taacgtttta ttgattgaca gattttccac
510121 gttagtttct acatcctcaa gtaaatgtgt taggtcaatt ctagagtacg ttttattcac
510181 aaaaccagta ttaatatccg gcaattgaac gtatttttcc ttatcactat tcgtggcccc
510241 gtctacattg tctaacaaca gtctctgttg aatgatggaa acggtagctt tgaatccttc
510301 aaataaagaa ggtaaattct tttcagcggc accgttgggt agcgggtatc gctgctcatc
510361 taaatgagca agtattctga aagttgttgc agagtctgca taattgtttt gaaaggaaaa
510421 tatccctact tgtcctttct gggtatcttt tgtactttcg ggccaagcca cctctctgaa
510481 cagtagaagt ttggaaagat atctgtagat ggggctcgtt atatattttt gaaattgttg
510541 ttgcgctagt atggcatgtg gtagcttatt aagtataatt tcgattggtt tagctaccag
510601 agagctttct cctctagtat cgcccgaacc catatagaga tactcttttt tactctcgct
510661 cgtggtaatc ttatatgtca ttcatggtta gttttttttt tatgactatt ttttttttcc
510721 attacgatga ggaaagttta tgtgagaaac atgaagctac atgctttaac aggagacaga
510781 cccatggtgg atccgctcag ttggttttat acatttagat gtaaggtaat acataattat
510841 atgatttgca gtggcctatg tatgcaatta ggacaaagga aatatctatt cttgaggaga
510901 agtgctcccc tactcttgca agttggctat ctccatttct agccgcctaa tttcatcttt
510961 ttcttttcga ataatcttag caacgtcgtg agaagaagaa ggatggtact gtgacatagt
511021 ctttaagcga tcatcttgaa gcaaaacttc tttcttgatg aagcgcaatt tggaagaaag
511081 ttgttcataa ttatggtaca attggtcgta atcctgcttg aactctgtta gtggccataa
511141 atctgttact tcggccataa ctttaagaat taaatcagta gggaaatcct cgacaaagat
511201 ggtttttctt ctttggttat tggattcttc ttccatgagc acgcttccat tttccaaggc
511261 atataggagc ctttgaattt gcggatcatc cttgaacacg gctgataatg ctttgaatgt
511321 acctgaactt gaatttgaaa tgacagagga tcctataaga tcggtatcaa aaataaaacc
511381 gttcaagcca ccgccacttg tagtggcggt tcttctcctt ttattgttca aatcaagacg
511441 atctttgttc aaatatactt ccttgggcac atggatgatc ggtttttccc ctggtctgcc
511501 cagccttcta tttcttttca tgtccgtatc tcgtttaata acatagtcga atactccctc
511561 cttgccgtct ctacgtgaaa cggattgttt ctcagggttg actttgaaca gaagatacgc
511621 ctcgtcgtgg ttacagtcct ttattagtct agtaatgtct tttctaatgc ttgccttgtt
511681 gcttgctccc tgtaggatgg cattatgaaa aattcctggt ggcttgaaat agagtgtgga
511741 catagagtcc accgccctat taatatcatc tatacatcta tccaagcttt cccccattct
511801 gtaattgcca cgtcttattt tgttaggtga tgatctaatt tttttgagct ttgtttattg
511861 attattttca aatgtctctt gcttattttc gcgcttccac aaggttatac actgagctgt
511921 aaatgtaagg tgtatggcat atataaatat atatatatat tcgtagtgtg aacattaggc
511981 taactgtaac aaaaatcgtt aatcacgcca ggctgcgtat acttcatcgg ttctgaattt
512041 ctgcgtaaca acagtttcag aaaagtcctt cacgatccca cccattctat actctagtag
512101 tcctgcttgg gcaatcataa ctccgttatc gatacaaaac ctattatctg tagcatgtac
512161 ttgcccattg gccctgtctt tacacatttg cgccatcatt tcttgtaatc gcacgttaca
512221 accaacaccg cctacgatca aaacttgatt ggagttaacg tgagccatag ctctttctgt
512281 tatttcaact agcatggcga ataggttctc ttgcagagag tagcaaagat cctctacagt
512341 gactttttgc tcgcccgttg tcttgtcgaa taggatctta tttttcttat tgcccttaaa
512401 tagatccttg gcaagtaaat cgatggaagc caatatacca ctcatcgaaa gatccatccc
512461 ctttactgta tagggaagtt ctaccaagtt ttctttgtga ggggcttttt tagctaactg
512521 ctcgatgttg tagccaggcg agggctcatt aggtatcttc agagttcttg caaatctatc
512581 aagacaatta ccgatagcaa tatcaagcgt ttcaccaaag atacggtacc ttttttccga
512641 gtatgcaata acttgtgtat ttccaccact tacatacagt accacaggat tttgagcttt
512701 agtgatttct ctccccattt cgatgtgacc aatgcagtgg tttactccca ccagtggcac
512761 gtcccacagt aaggagcacg ttctggcggc gatgacaact gaatgcagag gggcccccat
512821 gccgggacct ttggtaaagc aaattacatc aatgtctagt gtcgggcttt tgatgtcagc
512881 ttcggccagt gcttgtttta tgagtcttat gcaccaattt ctgtgatgcc ttgccgtgtc
512941 tcgaggcaaa aatccctccc caggaggtgt gacatatgtg tctctaatat tagaaagcat
513001 ctcagcttcg caatcataag atagatcgct gttggcatgt ttaggcagaa gcggatgctt
513061 aactatacca acgcccagtt tatttgcaga accttcaagt ccaagcgcaa tgtagtagtc
513121 cctgccattt ttgggtggga tagtgttcaa gttgaccatt ttgctcccga ctgcattagg
513181 gaacgcttgg gaattccctt cacgtaaaag ataaatatat gcatcgttgc acgaagtaaa
513241 aatggttact ctcgaactca tcataatgaa agaattcagt ttttccgtat aaagcgatat
513301 tacaggagga ataaaaagca aaataaaaaa tctccgcgac ggggaattga accccgatct
513361 ggcacgcgac aagcgcccat tctgaccatt aaactatcac ggaacgttat ttgttggatt
513421 ttttctctta gttttaaata tttatatttc gtcgaattgg tacctctaca gctcagaagc
513481 agatgtcttc aagttttttt attgtgtcta aataagaatc aaccattatc ttgacaaatg
513541 ggtgaatttt aagataattg ttgggatgcc attgatgata aagactataa tatacataca
513601 cagaatatac tagaaattgt actcgagcac ataggaatcc tcaaaatgga atcgatattt
513661 ctacataata atactacgat tattttctgc tttcgtttta tatgtttcat tatcctatta
513721 tattatcaat ccttgcattt cagctttcat tagattgatg actatttttc aaccttatgt
513781 cctcttctta caccgcatat gatagtatac tagcaatatg aatattacta aacagatgat
513841 atttcaacat catgttttgc ttagtagact cttgcgggcg ttccatccgt gtgaaataca
513901 tcatttacac ctcgctctgg gtcaagtaat caaaaaatac ctcgtcgaat atcttcgaca
513961 aatctgtcgc ttggtttatg tttgacctga tgtatataaa atcatcacta cccaatttag
514021 agaacacatt gcgttgcccg gccggcaaaa aatcctgggc caaaagttaa aagaaacttt
514081 ctcatactca ctctgaagtt gtactattac gaagcactaa agcattgata gataaatcaa
514141 cacagaacat acatgattaa attagacaca gctctctgta ttttttactg tttgaactaa
514201 ggttctaata cttacacatt cttttcaacc catcagatgg tgtcttgccc ctgcttacgt
514261 aacctacaac aatagattag acacaccagt gccaaggaca atatgttgcg ttctgactag
514321 tcgaagtatc attacgctgt gcagatcgac ctgacaccag acacaaagga gaataggggc
514381 agcatgagtt ccgtcggcga ctcattccga ccttccacag gtccgttgat tactttttca
514441 ctgatccggt ggaatctatg gttgtttttt tcatcatgat atctgtttta ggactttttt
514501 tttcagccga tcgcttatct gctcactaga atcgtaatca gtgatatttt tattaataat
514561 tattatttat ttttttttat accatttcct tttgataagg ggtcgttggt gccgtgccgc
514621 tatcaggcag cctcactaat ctacccattg acctcatgca gcaaagtcac atcgcccata
514681 tctctcgagt gcgataacgg ggaacttgat ttggtaactg ataagattgt taaatgtcag
514741 tttggatgct ttttcttacg tccgattagc ttatcttctg gagcaaccgg ccatttacct
514801 cctcatagta aattaaacat gataagcgca tagttggggc aacacacctt tcttccggaa
514861 ttcgctctgg atgagacata taaagatgaa ggtgaagtcc acttaaatga atgtcaatga
514921 gacgatgttt tttctcctag attgattttt gaattccttg tatacaaagt cttgttttct
514981 tattgtcctc aacaaaacaa aagtagaaaa gaacagacca aggacagcaa catttataag
515041 aaacaaaaaa aagaaataaa aaatgagtaa tacttcttcg tacgagaaga ataatccaga
515101 taatctgaaa cacaatggta ttaccataga ttctgagttt ctaactcagg agccaataac
515161 cattccctca aatggctccg ctgtttctat tgacgaaaca ggttcagggt ccaaatggca
515221 agactttaaa gattctttca aaagggtaaa acctattgaa gttgatccta atctttcaga
515281 agctgaaaaa gtggctatca tcactgccca aactccattg aagcaccact tgaagaatag
515341 acatttgcaa atgattgcca tcggtggtgc catcggtact ggtctgctgg ttgggtcagg
515401 tactgcacta agaacaggtg gtcccgcttc gctactgatt ggatgggggt ctacaggtac
515461 catgatttac gctatggtta tggctctggg tgagttggct gttatcttcc ctatttcggg
515521 tgggttcacc acgtacgcta ccagatttat tgatgagtcc tttggttacg ctaataattt
515581 caattatatg ttacaatggt tggttgtgct accattggaa attgtctctg catctattac
515641 tgtaaatttc tggggtacag atccaaagta tagagatggg tttgttgcgt tgttttggct
515701 tgcaattgtt atcatcaata tgtttggtgt caaaggttat ggtgaagcag aattcgtctt
515761 ttcatttatc aaggtcatca ctgttgttgg gttcatcatc ttaggtatca ttctaaactg
515821 tggtggtggt ccaacaggtg gttacattgg gggcaagtac tggcatgatc ctggtgcctt
515881 tgctggtgac actccaggtg ctaaattcaa aggtgtttgt tctgtcttcg tcaccgctgc
515941 cttttctttt gccggttcag aattggttgg tcttgctgcc agtgaatccg tagagcctag
516001 aaagtccgtt cctaaggctg ctaaacaagt tttctggaga atcaccctat tttatattct
516061 gtcgctatta atgattggtc ttttagtccc atacaacgat aaaagtttga ttggtgcctc
516121 ctctgtggat gctgctgctt cacccttcgt cattgccatt aagactcacg gtatcaaggg
516181 tttgccaagt gttgtcaacg tcgttatctt gattgccgtg ttatctgtcg gtaactctgc
516241 catttatgca tgttccagaa caatggttgc cctagctgaa cagagatttc tgccagaaat
516301 cttttcctac gttgaccgta agggtagacc attggtggga attgctgtca catctgcatt
516361 cggtcttatt gcgtttgttg ccgcctccaa aaaggaaggt gaagttttca actggttact
516421 agccttgtct gggttgtcat ctctattcac atggggtggt atctgtattt gtcacattcg
516481 tttcagaaag gcattggccg cccaaggaag aggcttggat gaattgtctt tcaagtctcc
516541 taccggtgtt tggggttcct actgggggtt atttatggtt attattatgt tcattgccca
516601 attctacgtt gctgtattcc ccgtgggaga ttctccaagt gcggaaggtt tcttcgaagc
516661 ttatctatcc ttcccacttg ttatggttat gtacatcgga cacaagatct ataagaggaa
516721 ttggaagctt ttcatcccag cagaaaagat ggacattgat acgggtagaa gagaagtcga
516781 tttagatttg ttgaaacaag aaattgcaga agaaaaggca attatggcca caaagccaag
516841 atggtataga atctggaatt tctggtgtta atgaatcgaa caacgacaaa aaaagacttt
516901 attttttaga taatcataat aaatatattt attttctcgt cattaatcta aagaaaaaag
516961 ggaaatgttt atagtcaaaa attgtatatt tccgtgcact aataagataa attatactat
517021 gaaagaaagt aaggtatttc tattttttta ctttttgtta ttttatttat gtttttctag
517081 gaaatgtaaa aataaatctt ttagtagaca gcgagatgaa aactaatctg tgtgagcttc
517141 aatcaatcaa tatgatttcc ccgcattttg tttgatattt taattgattc cgattaaatc
517201 cgctggtagc agttttgttt caaactaatt cagcctcctt actccccatt tccttattga
517261 actttgggga ttcggagttc cttttttttt ccgccactcc gataactaaa ctttgcagtt
517321 tcactgcttg ttaaacattt tcctactata aatgacattt aaaacgtaat tgagacaaaa
517381 aaagttaaat cgttattaac tttcactgcg gctccgctct tttcctcata aggaaatccc
517441 ctcttatgat cttgagaaat gggggaatgt tgagataatt gttgggattc cattgttgat
517501 aaaggctata atattaggta tacagaatat actagaagtt ctcctcaagg atataggaat
517561 cctcaaaatg gaatctatat ttctacatac taatattacg attattcctc attccgtttt
517621 atatgtttca ttatcctatt acattatcaa tccttgcact tcagcttcct ctaacttcga
517681 tgacagcttc tcataactta tgtcatcatc ttaacaccgt atatgataat atattgataa
517741 tataactatt agttgataga cgatagtgga tttttattcc aacagatctt gatataagcc
517801 ctgtcattga ttgcaaatgc acaaattccg gagattgaac agccaacaca aagatagtat
517861 ttgggactta gcgggttgag aacggtaatt atatcatgaa tactccactc caagcttgtt
517921 tgatacatca cattcttgta aaaatatatg atccaattcc taggacatca gaaaatatat
517981 ctactatggg cgtgtggcgt agtcggtagc gcgctccctt agcatgggag aggtctccgg
518041 ttcgattccg gactcgtcca ttttaaaatt tctttttttt tttttctctt tccgtatgta
518101 agcttttttc cttttttttt tttttttttt tttttttttc ttcactactt ttcaatgaaa
518161 ctctcttcaa aagacagcat gcagtaaaag cgccgatatg agtgacgacg attatatgaa
518221 cagcgatgac gacaacgacg ccgaaaaaag atacgtaagg ccaattttcg tcagaaagcg
518281 caggagagaa gaagactacg ttgcaactag caaagacaac atccaccacc acccatgcga
518341 ttggtccgcg aaaccatcgc aacgtcaaaa cgaaaatgag caaaaaagca ccatacggct
518401 tgtaccagtg gcgatgaata cgccgaagtg tcaagagaaa aaaaagaaaa gaaagggcgt
518461 tggtacaact agtcatgagg ctacgctttt cgagtacggt gaaagcatag caggctacaa
518521 gtgtgttaca accgagagcg aaagagaccg cttgaaacga agtcatgaaa gcgaaagcag
518581 cagtgaaagc gaggtagacg ttttcgcctt tgaccaggca aaaggtatca gctctaaggt
518641 tgaagccgaa gaacgctacg cgcgggccgt tcgacagtat tggcgcatga ccaaagacga
518701 gccggctacc ttaccactgc caggcacacc taccctagcg gctgtgagtt tagatatgat
518761 tgatgacaaa agcgtagaac aattttacac aatgagcagt gccttgatgg atgcaaacag
518821 actagacttg attcgccgcg atagaatccg gtggcacccg gacaaacatc gttatcataa
518881 gtccaaagtc acaaaactgt ttcaggccat taacggcctg tgggagcaag aaaagaccga
518941 gaaaaggtaa tgaaaaagtg gaactagacc ccacgtcagc gggcctaggc ccttcaatgt
519001 gttagaatac acagcgtgcc tagttcctgg tgcctggatc tcgaggccgc ggcactggaa
519061 aagccctttc ttttccagat cgggaaacct aatgagtcca taaaaagaaa tgtagaggtg
519121 gtgttgacgt tttgccgctt ttgggcaagt aggtctttct gcacggcccg gcccgggtcg
519181 tgcggaaaaa gaaaaaagca gacaaaacaa aatttttcct ttttttcgcc tttgtttctc
519241 ctgattcggg tatataagtg aataccatct aatgtgtttc cttctcgaga cctcggcgtc
519301 tcccagatca aagctcagca aagattttaa accgcaattt acgctccttt catcggtaac
519361 taagaagaaa aaaaaaaaag tacgaccaca caatttccag tgtattcatt ccttaaactt
519421 cgtttatttt ttattcattc attcattttt atttgaatat aaccaactac tagtccttcc
519481 tttaaacaaa aatttaccct cccttaattt ttcaagaaat tccagtatga aattatccgc
519541 tctattagct ttatcagcct ccaccgccgt cttggccgct ccagctgtcc accatagtga
519601 caaccaccac cacaacgaca agcgtgccgt tgtcaccgtt actcagtacg tcaacgcaga
519661 cggcgctgtt gttattccag ctgccaccac cgctacctcg gcggctgctg atggaaaggt
519721 cgagtctgtt gctgctgcca ccactacttt gtcctcgact gccgccgccg ctactacctc
519781 tgccgccgcc tcttcttcct cctcttcctc ttcctcctct tcctcttctt cctctgttgg
519841 ttctggagat tttgaagatg gtaccatttc ctgttctgat ttcccatccg gacaaggtgc
519901 tgtctccttg gactggttag gtctaggcgg ctgggcttcc atcatggaca tgaacggtaa
519961 caccgccacc tcttgtcaag acggatacta ctgttcttac gcttgttctc caggttacgc
520021 taagacccaa tggccttctg aacaaccttc cgatggtaga tccgttggtg gtttatactg
520081 taagaacggt aaattatacc gttccaacac cgacactaac agtttgtgtg tagaaggtca
520141 aggctctgct caagctgtta acaaggtctc cggctccatt gctatctgtg gtaccgatta
520201 tccaggttct gaaaacatgg tcgttcctac cgtagttggc gctggttcct cccaaccaat
520261 caacgtcatc aaggaggact cctactatca atggcaaggt aagaagacct ctgcccaata
520321 ctacgttaac aacgctggtg tctctgtgga agatggttgt atctggggta ctgagggttc
520381 cggtgtcggt aactgggccc cagttgtctt gggtgctggt tacactgatg gtatcactta
520441 cttgtccatc attccaaacc caaacaacaa agaagcacca aactttaaca tcaagatcgt
520501 tgccaccgat ggctctaccg tcaatggtgc ttgctcttac gaaaatggtg tctactctgg
520561 ctctggctct gacggttgta ctgtttcagt tacttctggt tctgctaact ttgtcttcta
520621 ctaggccttt tttccttgaa tattgcaaat aagcttttgc tagtactttt tttactccgt
520681 tcattttatg gtttattttt caattagttc gtttttccac aatacaaaaa aacacagtcc
520741 tttgtactat cccttttatt tcattatttt ttctttttta agataccact agatattatc
520801 atatatagca tattatataa cataaaaagt caagaaaaaa aatgttttta tcactttcta
520861 taactgcata tctttttttg catttcgaat gattgcttac acatcgccat gctgggattc
520921 ctcctctggt ggtgagacaa atggacctgc taattccaat gcaggttcgt caatgttgtg
520981 gtgagcgtat gacaaaacac caatcccacc ggcgtccagt aagaaacatg gattgtctac
521041 caaatgtctg taagattcca atttcacata tggaactgtg tcgtcatcat aagatttgac
521101 attttgaatt tcttcaatcg tctcacactt cttttgcaca cccagtccaa accaaatagc
521161 agcaaaataa cgcaatgcat gtccgtgcgc aaagaccatg atgtctgatg ctctgccctc
521221 actctggtgc ttgcggtgca agttctggat tctggcaata gcgcgggaaa gtctcaaccc
521281 aatttgctga gtagtctcac cgttctcaca cccatctctc cagatattcc atggcctctc
521341 cttgtccaaa ccgcgtgact ttctcaattc aatgatttct cgagtcagca ttccctcgta
521401 gtcaccgtac tcccactctc gcaagtcgtc gtctaccacc acacggatct tagctctttg
521461 ctcgtcgctt aatggtttca aaaccaaatc cacagtttgc ctggcacgca aacgtggaga
521521 ggtgaagata taagtgatgt tgtctggatt caaaaactga ttattgcgga aaacactctc
521581 accggtcctc aacatttggc cctcaccgta gggcgttaac ggtagatctg tcaaaccagt
521641 atactggcct gacttggacc attcagtttg accgtgtctg acaatgatac atctgggggt
521701 tagcgaaggc attgttgctt gcaattaagt gtaggtgttt ccctatccac ttagctatga
521761 acaaaatgtg cttatctgag ctaatatttt ttcatttttg tcctataaat aataatggaa
521821 aaaaaaaact catcgcgtgg ttgaacagaa aaaaaacaat aagagtgagt aagcagtgaa
521881 aaatgtaaga tttacgcttt atataagcag attttggttt cctttatata tttttgcatt
521941 tgtctatcct taacattgga tagcaatttg gcggtgggta gtttataacg tgtgtgctct
522001 ctctttaagt aacgatgtca agagatgtaa gggcagagaa actagccata tcactattga
522061 ttttatcatt gtttctaata ttccaattag tggctgagat ttatctcaat aatggtgatc
522121 agtaccatac agagactagc ccctttacaa gaggaagatc acatgtaacg cgtgtgccca
522181 accatgatgc tagtttatct ataccgtttt tggacaagat caaccagttt tggcatgtag
522241 gcggtgccac gcaaattagg aatattcagt cgatcaaatt gactcaggac cgtgatcaag
522301 ataaacatgg attagtattg tccaatggaa ttggcgacaa caccatcaat gactttgaga
522361 ttgttttcac tttcagaatt tctcacgacc ccactacaca actcactggt gatggaatgt
522421 gttttgccat tacgcccgaa aatgggtttc tcacacagaa tttacagtcg tcgtatgcga
522481 aaaagcaata catgatgaat tctcagggcg tcatagccga taatacagat ctgatgggct
522541 tcccgaaaaa tctgcctggc ctatttattg tcttggatac gtatcgcaac caaggccacg
522601 accataagga ggtacccttt atggatgtgt ttataaatgt ggccccagaa agcgattggt
522661 acgatataaa tagtgatggt gaactcagta catcgctgcg gcttaattca agaggccaca
522721 taaaactcaa gaaaaatgcc ctgtggaatc gagtcacgaa actaagaata atatatttgg
522781 aaagtataag cttcctgaag atcgacgtgc agtacgcaaa agagggaaac tactggattg
522841 agttatttca aacaaccgaa aatctgtact tgccgaaaaa catgcacacg gggcaaagat
522901 acattggctg tagcgcatta aatggccaat taacggagac agtggagctg ctggacgtat
522961 ccactagcga attccattgg aacgacatgg atgcgtccat tgaggacacc tatgattacg
523021 caaaggaagc tgagctattc ctggagcagg aatttggcga ggtccttgac agggaacccg
523081 atgagttcac caaatggaaa atgatcaaag ctcaaccaaa catcaagact gggtcacagt
523141 cagctgaaca gaaaacttca aacaatcctc actctcggtt gttcaaggtc gtgctgacca
523201 tatggcatta tagcgagatt ttgctattga tcatgggcat ttatcttttt tctgcttgca
523261 taagagtttt ccaaagaagg ttcaaaaaaa ttagatccag aagaaaaagg gcaggctcgc
523321 attctgtggg gctattgccc atgtagcatt gcataggcac gcacatacat acatacacaa
523381 ataatacaat ataggacgtt catcttaggt agccaattca cggtcttctt gtggtagtgt
523441 tacttgcgtt cgacggcggg agggttcttg atcgatccaa tatactctgt ggtgggatgg
523501 ccagaacgct agaattcgtc tcaaacgtcc tgttagagaa tattgtgggc ctcgtagact
523561 gtattgaatg aatgtccgag aaagtagacg acttcactga cgaggaacaa aacgatacta
523621 gcggaataac acttgcgttg tcgttttgtt gttgctgctg ttgctgctgc tgctgtctta
523681 ctttgcctgt tggtggttca tcccatgcca ctcgacggtc tccttcgtca tcggattcgc
523741 tcgaatgcaa cgaatttcga tcaaccaatg gtcgcaacga cgaactgatg gttgttccat
523801 ccggatccaa ctcagcacgc ttaactcttg tggggccagc cctagtgccg cgtcttggtt
523861 tactgctcga gaccgatgcg ttagttgtgg tagtggtgtt tattattttt ttaacccaca
523921 ctgaaagttt gtttcttctt ccctgggatg tatgatgact gtttgacatg ctaggacttt
523981 cccttggcac catgtatatt cacttttatt gtctcttgat cgagctataa ccaaattttt
524041 tttttttttt ttttttttcg tttttataat tttttctttg gtattcaatt gtatatagtg
524101 ctcaaacagc aacgtacata atagctagca aacaatagat gaaataatag aataataaca
524161 aataactata taagagtggc aggaaaaaaa atcaggcgca cgattagcgc aaaaccaaat
524221 tactaattgg tcgacacagc cgcgggctta gaattggttt ggtcttctct tgaggccttt
524281 agcttctcaa tggtggcatt gcccaagtcc aacccggtgg atacaatggc tttagggacg
524341 ctttcagatt tacttagatt gttttcatag acagtggtga agcgttggta ggtttcgtta
524401 agcttagtct ttgttgggtc gatgtacaca gactgcaact tgtcagttgt gggcttcact
524461 atggcgtcgt acttttcttt agccaggtcc ttggttgggt cgatatagtt cgacttgacc
524521 ttggactgga tctcctgcga catacctctg gtcgttgaag acaactctgc cacgtggggc
524581 aaagaagaag catcagtgac cttgttctcc tcaccggaag agccgatctc cttcgatgcg
524641 gtagaacctt gcaagtgcaa tggcttgatc aggaactccc tcaacagagt attagaaatg
524701 ttggcgacgt agtcgacgaa gaaccacacc agccagatcc ctggcgtgtt ggaatgtgat
524761 ttccaattgt acagcaagcc gtcgacaccc tccttgaaca ccaagaggtt aactaactcg
524821 tccaacttga aggccccttc cttcccagca gcaacaactt gcttcaccag acgaggagag
524881 ctggacgatt cggaaaccca ctggttcaca gatcccaaaa caacgaggtt gaaggaaatc
524941 aatctctcca caggtggcag agattccgca tatttaataa acttggataa agctgggtat
525001 ctttgcagat gcgaccaggt tgcttgtggc aattccacag atggtttaga agaagaaata
525061 gatgattcag acataattac gctacggttc tggagagtga gtgatggtta atgattaccg
525121 atacattccg ttatctttcc ttttataacc cttgctgcta tattattaaa tccgaaagaa
525181 tacgatcatc ccccacggcg gagaaaatct aggctattat tatcattatt attattatta
525241 ttgtcgtctt agttacatgc gctttaacat atatttcagc ttacacactt acatgtatat
525301 acatatatat atctatatat gtatgtatac atatgtatat aaatatatga atacggttat
525361 gaccactctt gcgaagtgcg ttgggattat gactgcttgc attcaggagc ctgttccggc
525421 ctgccagcaa aatcgtcttg ctcttcggca gattccccgt cgtcatcctc caagccgtga
525481 tcatcatctt cttcttcgtc ttcgtcctcg tccgcttctt cttcgtcctc ctcgaactcg
525541 aattccaagg ctgcgccggt aaaccagtcc acggctctag gaattagctt gtccttaagt
525601 tgttccccga tggagtagtc taaagctaga cgttcctcga ggtcttcctc caactcctcg
525661 tcttggtctt cgttttggat cttgggaggg tcgaagaagt tgaaaaagga ttctatggga
525721 gtgatcttct cgatggtcct cacctgcttg gtggtcttgt ttctctgctt gcgcatttct
525781 aggtccacag tgacgttgtg ggcgttgtcc ttccaactga tctcgcagcc ttctgcgtgg
525841 tcgtagataa agtccccgga gtaaccgagc tccttctggt agaagtaggt cttgcacaga
525901 atgtcgttgg tgaagaatgg gttggcggaa gaatcaaatc tgaacaacag cttgaaaccg
525961 ggtctaccat ccgtcaagta ttccagacca atatcttgca ggtactccag aacttccgca
526021 tcgcggtcag tgatcgtgtc gcaaacgatg ggcaagttct ctaatgcggt tagccagaat
526081 gagggaattc ccttcacctg ttcctcctcg gaatcatttt gggccttctc ttcttcgtcc
526141 accaacaact ccgtctcatt gagtgactcc acaatctctt ggccctttgc gatctgttcc
526201 ggcttgggtt gctcttgtcc tgaaatgatc ctggaccgct gctcccaaat gggcttgtac
526261 ttctgcagaa acttgttctc tagctcaaac atctccacct gaaattcctt ttcaacttcg
526321 aatagctcgc tttgtaaagt cttcaagctc agcagctttt ccttaacgtt cttgggaaga
526381 ccccccacat acccgctgtc ctggcccacc agcgagccaa gtctgtcctg gatggactgt
526441 aacaacaggg gttggttagc caagatgtcc tcctcgttga tggtgccgat cttgtcatcc
526501 tgctcctgtg cctgggccct aactgggttg ccgtttttca aatagctcgg attcagaacc
526561 gatgctgggg tattgtgagg cgtaggggcg ttgtcgattt gcatcgacga cttgggtttc
526621 gttctgatag ggtctgacat gatcttgcgc tttgctcttg gtcccactgg gctcactaaa
526681 tcctcctaat ctaccatcaa actgccattt ttgatcccaa acgctgctat ttaaaaggaa
526741 aaattttccc aattacgcgg gtaatacaaa aaagatatag cccattgtta taaaaatatg
526801 tatgtgttca atatagtggt atataggtgt tatttgcgct gaatgatgta cttgtcaatg
526861 tctgcgggct catttcccac caacttgttt tcccagtcga cccaaagcgc ctcctttgga
526921 ttccaaagtc ccctctggac acacttctgc aggtccatcc cgaacgtcgg gtctgtgtgc
526981 ttgtatttga gcactgaatc cagctttgga atctgccttt gcaacgaaac tgggccttgc
527041 gggcacgaag ttctcatgta ttgcagctgg tcccacgtgg gaaagcggtt ggcgatttcc
527101 acgtcgaatc gatgagagac gtctcccttc agcaactgca ggcatttctg cgacttgata
527161 ttggacgcga tgtcattggt aaacaacgag atggtacgtg gctgtctctg caatgttttc
527221 caaaacgaca tttattgcgt ttgcgtttgc gatctcccgg tctgttattt tcatttgcac
527281 ttttcttaac gttctctttt ggttttatat gcccctttcc aagctgggtg gataccccgt
527341 ccattgagtg cccgtgccca atcaagctaa agccagacta aaaagaggaa gagttcaaga
527401 accatcaatg cctccagcac aatttcacaa cagcttgaca ctttggcaac ggttatatca
527461 gagcatagcg acgggattag agagatgcaa gacgacggaa gaaagaaggg agtgcccggc
527521 atgcgctgaa agcgccctgt agtacaagcg taccgccgtt gaataggcca tggtacatca
527581 cacgatgatt gataatttga tgcaagctgc catgctcaga tggttgtttc ccgtttctct
527641 ctttcacttt tgatctcctg cgaagaatag gatgagatgt gaattttcgt ttctaatccc
527701 ctcggccgtg cggctgaaaa agagaaatga tattggaata actaggtttc agatgatgag
527761 aaaagaggct attttgtact attcaccgac gataagaggc tgtaagaacc actcatgcca
527821 acagctaaga ggacgtcatc cagggcttcg ttggcactgc ccttccagtt acggttggtg
527881 cacaagaaat catggggcca tcggctaaga gacttcattt ccgggttctt aaaatcatgc
527941 agacccattg ctaaatacgt tttccccaac ttcatcgtgg tgcactatat ctacctgatc
528001 acgctgtcga ttatcgggtc cattctgtta tatccgtgca agaacacggc gttcatcgat
528061 gtgctatttc tggctgctgg agcgtctaca cagggcgggc tggccaccaa gagcactaac
528121 gatttcaacc tgtaccagca gatagtggtg tacgtcatta cattgctgtc cacgcctata
528181 cttattcatg ggtttttggc ctttgtcagg ctgtattggt ttgaaaggta cttcgacaac
528241 attagggata tctccaaaca gaattttaaa ctaagaagga ccatgacgtt gcaacaaagg
528301 gaactatcgg gcagcagtgg caatgccgct cgaagtagga gtttcaagga caacctgttc
528361 cgtgggaagt ttgtttccag agaagaccca cgacaatccg cttcagatgt gccgatggac
528421 tctcctgaca cgtccgcatt gtcctcaatc tcaccgttga atgtttcctc ctctaaggag
528481 gaatccagtg acacgcaaag ctcgcctcca aacttctcaa gtaagcgcca accctcagac
528541 gttgacccaa gagacattta caaatcgata atgatgctac aaaaacaaca agagaagagc
528601 aacgcaaact ccacggattc tttttcgagc gagaccaatg gacccgcttt cattgtgcag
528661 gaacgtcatg agagaagagc cccccactgc tcactgaaac gccattctgt cctgccatct
528721 tctcaggaat tgaacaagct agcccagacg aaaagtttcc agaaattgct tggcttgcgg
528781 agagatgaag gtgaccatga ctactttgac ggtgctcctc acaaatatat ggtcaccaag
528841 aagaaaaaaa tatctagaac gcaatcatgt aacatcccaa cgtatactgc ttcaccgagt
528901 cctaaaacct caggccaagt agttgaaaat catagaaact tggccaagtc ggcgccttca
528961 tcttttgttg atgaggagat gagcttttca ccgcaagagt ctttgaattt acagttccaa
529021 gcgcacccgc ccaaaccaaa acgacgtgaa ggtgatatag gccacccctt caccagaaca
529081 atgagcacca actatctatc gtggcagcca acctttggca gaaactccgt cttcattgga
529141 ctcacaaagc aacaaaagga ggaactcggc ggtgtcgaat atcgtgcttt gagattgctg
529201 tgctgcattc tcatggtata ctacatcgga ttcaacattt tggcgtttgt gaccatcgtt
529261 ccatgggcct gtacgaggca ccactactca gagattatta gacgaaatgg agtttctcca
529321 acctggtggg ggtttttcac tgcaatgagt gcattcagca acttgggtct gtctttgacc
529381 gctgattcaa tggtttcctt tgatactgcg ccgtatccgc tgattttcat gatgttcttc
529441 atcatcatag gcaatacagg cttcccaatt atgttacgat ttatcatttg gatcatgttc
529501 aagacctcga gagacctatc tcagtttaag gaaagtcttg ggtttctctt ggatcatccg
529561 cgcaggtgtt ttacgttgct gttccccagc ggccccacat ggtggctgtt tacaacttta
529621 gtcgtcttaa acgctacgga ttggattctt ttcataattc tggatttcaa ctccgctgta
529681 gtaaggcagg ttgctaaagg ttatcgagct ctcatgggcc tcttccagtc tgtatgcaca
529741 agaactgctg gattcaacgt tgttgactta agtaaattac acccgtccat tcaggtgtct
529801 tatatgctaa tgatgtacgt ttcggtcctg ccgctggcga tttccattag aagaacgaat
529861 gtttatgagg agcaatcgtt gggactatac gatagtggac aagatgacga aaatatcacc
529921 cacgaagacg atataaagga aacagaccat gatggcgaat ccgaagagcg agacactgta
529981 tctacaaagt ccaagccgaa gaaacagtcc ccaaaatcgt ttgttggtgc tcatttgagg
530041 aggcaactct cttttgattt atggtaccta ttccttggat tatttataat atgcatatgc
530101 gagggcagaa aaatcgaaga cgttaataaa cctgatttca atgtctttgc tatattgttt
530161 gaagttgtta gcgcttatgg tacagtgggt ttgtcattgg gttacccaaa caccaacaca
530221 tcactatctg cccagttcac cgtattatcg aagctagtca taattgccat gctaataaga
530281 ggaagaaata gaggtttacc atacactttg gatcgtgcca tcatgctgcc aagtgacaaa
530341 ctggaacaaa ttgatcgttt acaagatatg aaagctaagg gtaagttgtt agccaaagtt
530401 ggtgaggatc caatgactac ttacgtcaaa aagagatccc acaaactgaa aaaaatagca
530461 acaaagtttt gggggaagca ttaaaatcaa gtttacccct ctttacctac ataagagcca
530521 acgtaatttt ctctcagtat tatatgtatt atctccgaag tttattattc tttaacgaaa
530581 tataaaagaa aaataagaaa gattaagacc ctaaaaggtg taccactacg attcaacaag
530641 cacaacgaat cctatccgta atatactttt gatttctgac tattctagaa aaattttagt
530701 tcattttttt tccctctttt tacttattgt atttttcaca attgaattgc attttgtccc
530761 ctacgaaaaa aggcagaaaa cgagatctaa accactttca gatcagaata ataataataa
530821 taataaccaa ccaaagccat caacaggtcc actagaagca tctgccaagt tacgacctaa
530881 gcaaaggttt gagtgaaaag tgaattgcga cagtacaatc acaaaagtat agaaacataa
530941 ttgttatgga aaacaaacta ctttgttggt ggttgtactg gccatgcgtg tattcatcta
531001 ttatagctac cataatatct ttttacacca taactagaca cttattaaat taccgtaaac
531061 catatgaaca aagactatcc atacggatac tattgctcgt gcccattttt agtgtgtcat
531121 gcgcaagtgg cataattaag cctgaagcag ctcaatttta tgtcgatcct atcagagaat
531181 tttatgaagc attcgttatt tacacttttt tcacattttt aacactacta ctaggaggcg
531241 agaggaacat cattactgtt ttaagcttaa atcacgcccc cacaagacat ccgataccgc
531301 taataggtaa aatttgcaaa ccgatagact tatctgatcc ttttgatttt ctttttgtca
531361 aaaaaggcat attacagtat gtttggttca aaccatttta ttgttttggt acattgatat
531421 gcagtgcatg gaagctaccc aaattcgaaa tatttttgaa cgttttttat aatatttcag
531481 tgacttggtc actgtatagt ttagcactat tttggaagtg tctctatccg gaattaactc
531541 cttataaacc atggttgaaa tttttatgtg tcaaattgat tatttttgcc tcttattggc
531601 agagcatcat aatccagggt ctagtggtta ctggaaagtt gggtacggga aaccaagatc
531661 gaacctctgg atatgtgtac aagaatgggc tcctgtgtat agagatggtg cctttcgcca
531721 tcttgcatgc agtagctttc ccttggaaca aatacacagc atttagcata ccttatgggg
531781 ccaggatgaa attcatttac gctttgaaag attttcttgg ttgcggtgat ctaatatggg
531841 attttaaaca gactttgttt gctggtccct tgtactataa ttataggaac ttcgatcctg
531901 aagccatgga tctattaagc actagacaac aatccggtgc gactatggaa agactaaagc
531961 atgggctaag atttactgat aatggaagaa atagttattg ggtggcatat gggagtatag
532021 ataacaacct tgttccggaa tcaatagagg aatcatggga agatgatatt gctggtcaga
532081 gaacttttcc tgaggatcca aattatccgg ttgttcacga ctacacgatg ggccatcgat
532141 atagtagatc aatgaatgat ttaagaagag atgttcaaag taggtcatca atggcttgtt
532201 aaatgagtcg ttaaatgtac gtatatacat agttactgcg ctttcggtta tatacaaaat
532261 aaaacaacat ctacaagcaa tgcttttttt tcaattattg taacttggat gcttattcta
532321 ataaaatgaa ataaatgcta ctgtaatttt ttgccggagg attggctata tatgcagagt
532381 gggagttgga cgatatcacc attattatta tttttctatt attaccattg gacttgtctt
532441 ttgcagcaac aaaagtggca gcagcagcaa cagcaccacc accaatgcat tttggccttg
532501 ccttttataa gttgtcaaaa aaagttgacc tcgaaaaggg gaaaaaacat caatttttca
532561 ttaaaaaatg cttagcacat tcatatgcag tccaagaaat ggcagtggct ggtatattag
532621 ccactatcct tggtttcaaa cctcgccaaa accccttcca accatgaacc tccagtatgg
532681 ctcttgaggc tctaccaaaa gtgttcgcat ccttcattat ttcgatggag acagtttcgc
532741 tgcctctaac ctgtaataca gtctttatgc aatccaacgg tgtagttaac gcagcacatg
532801 ttgcaccact tatcccaccg caaagacaat gaatcaatgg attgtaggaa ttttgtgggt
532861 tgaagaattt gctggcagat tcatatatca tgaaattgaa cgctgcaaat gggatattca
532921 tggccaatgt tgtgggatag gagtagtaaa atgctgcaaa gccttcattt tgatatattt
532981 gcttagtaac attccaaact cttagattag tatccaattg tagtctttgt ttaacggtgt
533041 caaaggggtt catcaatgca tccgcagcaa tggtagcaat ggtaccactc agtgcggtct
533101 tcattggttg atgagtttgc atatcttcag ggcttatcag gcgagctttg caaaactcgt
533161 atgtaccaaa atatactgca tgcgcaggcc ctgcccccag tattaccgat tgaacaccct
533221 tccataaagc catcgaacct tccattgtag atattttgga tatctgagat atcatccctg
533281 tagaggcagc tttattcaat cctgcagcct gcactcgggt tttcagagca tctattggaa
533341 acatcaaaga atgctccatt atacctgcaa atgctcctgc cagtaactgg gaatgtagcg
533401 gagcatgtga tggaagagct tcgtagtcga tttcctcagc tattgacagt tctgaagtat
533461 tcataatatt aactgatatt tcggttgagt tttttacttc ttcactttgt acttctcacg
533521 aaagtcttcg tcaataaacc tctgataaag tgaaaattct atgagattcc aataaaacct
533581 ccaaatatct ttatatacag cttactactt agataagatg acgttcgcca atggtaggca
533641 aaagatagca gggtgttctt gcctttcagt cttcgccatg ctctcattca agaaagggtg
533701 ccaaaatacc gaaaagagac acgatcgggg gtgtcaaagt agcgattcct gtgggttaaa
533761 agagggtgaa ccacggcaaa catgcatgtg taaaacccaa aacgccgatc tagggcctgc
533821 gacgcatggt acgaacatcc tgaaggtata taaaagagct aaagtcttga ctcatgcctg
533881 aaatcttgat ttttcattgt tatatcctct ctatacatta gtaagcacca tagatgggct
533941 ggctatcaaa agcgagaaaa aaaaaatgct gaattccaaa tatgtactca tcggggtgaa
534001 tttcaatgat gtgttatgta gatacaatat atatgtataa gtcactaaat gcatacatac
534061 gagagtctac cttaagtttg tccaagtgaa aaaaactggg catagcaaaa agacggttgt
534121 aggtatacct gcgtatatga gaaaccttcc gacgatttcc actttggaaa caccgctgta
534181 caataaacac tcttcttctt cacttgtctc gttatggaaa tgaacctttt cgcttctatc
534241 atcgtgaaat ctgagtagtt taattaacag cgtgtagaca gctgtcttgc taatgacgtc
534301 tttccaaaca atcacagaag cgacacctac cagaggcctc aagaacacct tagaaccaca
534361 tgatgcgtac ctactacata caaggttcca tccgtatctt tcggttaacc agtcgctgca
534421 atccagccca ctgactacgc caatgaacgc tacgctatct tcgaaacaag gacattcatc
534481 aatgggcctg acgtggttaa acagaataaa caagccccat gctacactca aaaggggaaa
534541 ccagagatgt tcaccaatct ggaaatttcg taaagcatgc accacccaga ttcttataaa
534601 aaaacagata gctccaactg cggcgccgct aaataaatcc agcataccat gcataccgca
534661 gtaaactcta ccaaaaacca gggttaagta gtaaaatatc accagactca gtaaaagaag
534721 ctttgttggc cataccagtg tgtcagataa acatattctc caaaagaata atagacttac
534781 cgcagtagcg ttagcagaat gtgaactggg tgcaccatat tctttcgtag tgtattcact
534841 tagtgtgatt ctgtcaactg gcggtgattt tggccttggt aggcaccaat aatcctttaa
534901 gtagccactc aaataaattg aataaccaag aacgtagatc atgtcccgtg ttaaatcgcg
534961 gtatccaagc cacacaggca tgggaagcac gataacataa aacatgtggg aacccataag
535021 cgaagtgtat ttgaaataaa cgtctctaaa aggcgttctg tgcttttttt gtaaagaatg
535081 tacgaaatct gattggttgt ctgtgaatct agttagatac tgccttgttt gaaaccttag
535141 ccacgacatc tggctctcaa aatgctccgc tggatgatta ccgggatctg ccaataggtg
535201 tttgccgccg gaaggagcca tctgaacctt aatggtgtcc tcggtaacac ccaattcagt
535261 aaccgtctga ataatggtca taattaaatt cttttacagg cttgctattt tgtatatttt
535321 tttgaagact accactgcct aacttctttt tgtcatgtta tcaattcaac tagatgttga
535381 gaaggaagcc aaggcaaggc tgataaaaac taagaaaata aggaaaaatc attatgttat
535441 ataacatgaa ttctagacgt acgtgctcgt agttaggaag tatctaaata agagtcccca
535501 cgttacttta attagaagca cgccatcttc ctacaaccga tttttttgga ttgtagatat
535561 cagagtctca tcaaacaaga ggaacccaga ataggcacgt ccactgagaa aaccgcggac
535621 aagcaagaca cgcgtacctg aaaaggctac atttcttgaa gaagttgttc agttgagcta
535681 gccacctctt tagcctgaag acgttcgtaa ttcaaaatag attcccttgg caattgaagc
535741 catgaactga gtgaatctgc aggctcaatc gtattagaca gtatggcagt aagccttgcc
535801 cgttcctctt cttcactttg ttgaagaaga ggctgtggga ttcgtacccc aggaacgatc
535861 tgcaaattgt ccgagccgca gaatacgtgc gcacaaagtt tagcgaccac ttcaaggtct
535921 ttctcttcat cgatctttcc tccgtatacg atcgtagcta tgtgatctcg cacttgtgcc
535981 caaggaatgt tgttggtaga attggtggct aatacattct ctaaatacac tgaggcaaat
536041 tgaaagtcgc aatcattaaa gtaatacttc ttggaaaacc catgaggaac caatcgggtc
536101 ctggcagtga tcaaggcatg aaaccatgac aataggaagg tacaatacac gctccatact
536161 cctgaaattt taccagtgaa aaattgagaa ccccatagat ctttgacggt atctagtata
536221 cctgggatat cctcatacac aaatctatca gttctttgta gcaatggggc aggtagttta
536281 tcaccagtca aatggcatgt catgaacatt ttgaatttct catgttcttc tgccgccttt
536341 gtctcctcaa catgcttgtg cagatacgtt ttcacccatg atagcgacat ttgtatgttt
536401 tgtaataata tccaaccacc ttctatctta gattttgata tttcctcttg agcatagttt
536461 agattttcta tagaccctag cgggatgatt tttaacgatt ccttcgaggc tttcgccaat
536521 tcgattaatt tgaatgtgcc atcaacatct cgctcgcttg ccattgtaaa atagttgttc
536581 tcggaattgg ctaccacatc cgcgatattc cactcatcaa caaaaaactc atttttgaac
536641 cagttcaacg cagatatata cgatttggtt gtaacatagt cccataagta ccgcaaatca
536701 ttatttgtat ctacggttag ttttggtacg ccatcgctac tttcagagag aactccaatc
536761 atagttagaa ctgcctcttt atattgttca ctttcaatgt cgaatttata caaacaaaac
536821 atcgtcatag ccataatcat tttaaatttt ttgtcaagag cggtggagaa ttgacaatat
536881 acttcttgat ataatagcca aagaatttca tctacccgtg tcctagctgc tcttgtttcc
536941 ctagatttct taatgaagac acgtttgaaa catgatagaa attgtcctat agaaatgccg
537001 taaaaccaat gaaactgacc aaacttctcc aacatagaga atattttgac actatgctta
537061 ccgataatag aatactcttc taccagatta tcaaactgtg ggaaaaactc ttcagattca
537121 cttagctttt tttcaatgtt catggcctct ttcttcaggt tgttcaaagt caccatcagt
537181 tcatcatttt ccaacatatt cccctgtgag ttatttagtt cctccaaaag tcgcttttct
537241 agattcttca gtttcaactt gtattcggta ttcaatttta tcaaatcttc ccttttcctt
537301 tgcatttctg cattctcttc tgtcaaagtg atgtcaaaaa ttcgtgtctc aatactttcc
537361 ttattcgtga caaaatgaac taaccttacc ctagatctga ggaatattgg aatatctcca
537421 ctgggatcgc aagagtgaat gaataattta aaatcgcctg aaacatctac ttcatgatca
537481 ccaatctcca ccgtgactct gtttccggca tgattgaact ctctggagat tagtcttgat
537541 ataattggat caaagaattc tccatcctga attataacta cacttccgaa tctaattgca
537601 ttttctaatc ttttaacaaa accttcttca agaaaactga gaagtacagt tttattacca
537661 taataattcg agataactgt tatcatgtgg gagcttggat ccaaaagaaa aggaacagcg
537721 tcttgtgaat tcatgactat gctcatattt tccaaaaagt aatcgttctt atccaagcca
537781 cattcaagcc acttcatttt ttcatctagt gttaccaaat aatcgatgaa acgataattt
537841 acatcatatt taacagcaaa tttgcctagt aggcgcttta aaatgactaa catgtcagct
537901 ctttcccttt cattcaaatg accaaagtat gtttcatata tggatgaaat tatgcaattt
537961 ccaatcagct cttggctcgt cttactaaat tgctttgtag tgttcagcca cctttctttt
538021 tcgaaggtta aactcttaac taaagatata gacctatcaa gattagcctg cacgttactc
538081 atttctgtct tgatggcctc aacatcccta atcaacaaac tatattttcg ctttgaaact
538141 tcaatacttg cttctaaatc ctgtgtcatt tcttcagcgg caagtaaatt ggccttcgtc
538201 ttcaatgatt cgaactctat tcttttcatt tcttgtctca gcggatctac gttttctaaa
538261 actttactga agtttatttg ggcattgacc cactgatata gcggcccaca cgctttgctg
538321 gccctgttaa ttgtctcata agtaaaatta ggatctgaca aaaattcttc ctccatatat
538381 tttcgaattt ggggcttcat atgtaaggtg gtatcataat gtactatatt atgaataaag
538441 tcatcttttc taataaattg ttggatatct ctccagttgg aaaattggta gcccaagatg
538501 gcgcaaacag cctccataac aattttcaca ccagaggggg ggttgaccat tgatctgatt
538561 tctgtcaact gttgcttttt tatgttcttt acaccccgtt gtgcctctaa aatggtaggt
538621 tcgatatctt gaatactttt catgacgacc tcctttcttt ttcttatatc ttcttcttgt
538681 actttcaata tctttttgat ttcctctgta gcctcctgct ttctttccga ctcgttttgc
538741 tccataagca ttttatccaa tgtactccgg gcttcctttt ctttctcagt aagttccgta
538801 ctcttctttg acaaagtttt gtttagttcg ttaaccttca agacagactc gtttagtttt
538861 tcgagaccta cattaacaaa tctttgattt tcctgtaaat cttgatattt cgccgtaaca
538921 agcttcacta aggcacgtaa accatcaata aaatacccag gtgaccttgg atttacccca
538981 accttcattt tttggtaaaa atttctatca aaatgtatca gaatattaac cacagcatct
539041 cttatagttt ggattggctc cgtaaatacc aactctttat tgacctctgg aactataaaa
539101 tcggtaaatt ccatagggat cacgtccacc atattgttgg ccacttggga cattgttttc
539161 gtatcccaat cacccatcca attaattatg caacgattga aaagggctgg agaacttatc
539221 attgctgagg acttattgtt tgtaggatcg cagatcgtga agacaacatg aaggtttttg
539281 gcaatttctc caacaaacca gtcatacagt tcttgttctg tatccaataa aagacctaaa
539341 gacctggttt tatttcgcaa gttattcaag agcttatcat actcctctcc ttgaaacaaa
539401 tctggtatat cagcgttggc aagtaatgta ttcattctct ccaaaaaagc cgtctctaaa
539461 atgttggatt catcaatgat taaacaagta cgagattctt taagtgaaca gtctgaaata
539521 gcttttttca aaatcatatc aaagtcgcta agattggaat gacggtggat cttgggttga
539581 acaatcttca aaccgttcaa ccacgcgaca aacctagtta aaatagtttt acctgttctg
539641 cttgcaccaa ttagcatcat gtgaccttga acttgtttta acgcacgatc aatacgcaaa
539701 atatggtcaa ccatagactc gtgtataacc attggcactt ccagctcctc atcacagaat
539761 gttttaaatc tttcctctat aaagtttaca agatctgttt tgttgacctc tttgaaatca
539821 aggctcaaca agcccgaaaa gagaagtgaa gttgagctta tattacccaa atcctgatta
539881 ggtaaatatt tatcgactgt ctcataaaga agttgttcaa aactgttttt ttcttttaca
539941 ccaaccagcc tatctgcaaa tattctccaa gcttcgtaag cccataaccg tattagtgat
540001 cttagtgttt gccttggacc agtgttaatt gcagtgtaga cacccctaac caaacgtgtt
540061 aattctcttg gtgaaaaaag atagtgtgat tgaagcccag tactgtatct tgctttacat
540121 tcgttatata aatgaacgga agcgcgggcg aagggctctg tgtatgatct gaactcaggg
540181 actagcttga aaatggcttt gtaataaatt tcataaattt gagaaagaga ttttccgctg
540241 ggataaccta ggtaaagaat agcagcatgt cgtgtaaatc tttctgacat aggaattcta
540301 cctgggtcgg ttggaggatt gcaggcacca acaatatgta tcctctctat tgtcacccac
540361 ttattttctg gcgttttcca aaatccttgc ttttccatca actgccttaa gaataagacg
540421 acattttgag aaccatactt gtcgagtttt ggtaaattaa tctcgtcaca aaataatacc
540481 aaatttttta tatccgattt tggtaacaaa gtaaggcctt ttgatgtagt tacgtagttt
540541 gtatgcctat gcaaggctga caaaatatgt tctgtggtcg tgtctttcga aaaatttatt
540601 ccaacaacat catagagcga agagttccgg agtgcattat tcataatcat tgttttacca
540661 gatccaggtg gcccacaaag gataataccc ctttttgaat tgagcaagtc ataaaaaatt
540721 ttctcatgct taatcgtatc aattgtagga ataacaatgt caggcctcat gacctcatgt
540781 gcttctaaag aaacagaggg aatttcggaa caaaaggaac taaaactcaa cttatcgttc
540841 gcaataacta tggtagaata atctgatagt tcttggctgt catgtccaaa ataagtgttt
540901 atagtttgta taaaagctct ttgtgattca ccagttgaat caccagctag tgcatatagt
540961 agggatctct taatcaataa agtaatcaca tctttcaaac ttttatcgtc caagttttga
541021 aaccactgcc tataactcga tattaaatga acagccaact gcaccgcggt ttctaactta
541081 ttaaaggttc gaaccccgag aatgtgaact aaatcatttg aacacgtaaa aatattggtt
541141 aaagaggcca tatcaaaaga atcagatata aggtccttca acttatctaa ttcaaacatg
541201 gatagtttat tatcaagcgc ttcataactt ttattcagta ggtggtcaat cttggaggat
541261 attgaacaca catccgtaga aaaccacagc aaaccacatc ttgttatagt agcaggtgta
541321 gtatggtcaa ggttatccgt ttcaaataaa atgcgaaagt tcggcggaat aggaagtctt
541381 tcaccgtttg gaagcgttaa aattttatta tcatcaagaa cagaattcat ggcttccaca
541441 tattctgggt ctaaatcact atcaaatact acccaaattc tcgaattctt aaaagttcct
541501 gtgatatcat cgttaaccct tcttagaatc gaagtaaaaa gcccatctct ccactctagc
541561 gttgctttaa gcatacttcc atacaaggat tcttttgtaa gaacttttgt atcaataaca
541621 tagacgacgt tagcgtgacc atcaaaaatg gccatggcat caataacagt tttccacgtt
541681 gccgttttac cacagcctgc cttacctacc agtatcaaag cctgttgtgt tttttgcatg
541741 taataaaact gcatacattt cttgagaaat tcctcagaca ttgaaaagcc actcctttga
541801 ccagcgtcct ttaaacattg aacaatagcc ttcgaattta gcggcgttcc agcagaatca
541861 aatattttcg ataattcgtc tttgaatacc aattcatcgg tgtcaccgag cgatggtaaa
541921 atcactcttt tcaaactttc gactaccgtt ttttcccctt caccaaattc actaatcaaa
541981 gggctgcaat ttcttaatac accttttagc gttctcaaac caaaatgata atggttcatt
542041 gaactgcatt ttgaagacaa cagttctaaa aaatgaacaa ttttcgaagc taaagactta
542101 gaatcttcga accccataat ttgtaatatc atctctgcaa tagtaccact ttgcggagat
542161 ttcatagaga attctcgaaa actcttcttc aaattttccg gtaactctga ccttccatta
542221 tacccaggat tcaaagtaat aaacactgca gtgtgagggc tcaatggagt ttcttcttct
542281 aaaagtgtaa tatgggactt accaacctgg aggccatttt gtatttgttg gatattggca
542341 gacaccgcac tcaaaacttt ctcatcgagc ctattgaatt catcgaagca tccccatgcg
542401 ccaatctgtg tgatacctac tagaagcctg gaaagaacct gataatcgaa ggaatcatca
542461 caattaaaaa ctacaaccac gcgaccgaga ttttgaccaa atgctttcac agtttctgtt
542521 ttacctgtgc ccgcaggacc gaagaagcac ccaccatatt tttgatgcag agaatctgtg
542581 agtgtcgcaa acccaataag aagcaacggt gtatatatta atctttctgg gatgccaata
542641 tactcaaatt tatattgcaa gaggtagcca ctctgagaaa taaaaacgga gttgagatca
542701 tctaaagtgt cattcttttg ataaaacttt tgaactttcg cccatagtag tcgagcttct
542761 tccttagtgg aacaattttt aagctgtcca ataacgttat taaaatgcaa atactcaacc
542821 agtagggcct ctattttttt cttcacgtta tcggaagatt tattcaactt atccagcagt
542881 cccttaatct tcatatcaac ttctttccag tactttgaaa attgattagt ttgaaggcat
542941 ttttcaacga gctccgtcca cataacttga gctgagagaa gaatggcttg aaagatatat
543001 ttagatacaa ctacttcaat gtccgttcca tctttcagtt ggcccaaaca gtctctaaat
543061 tgagtgaaga cgcttagctt aatttctgtg tctaaaatgt ttaaccactc ttgagcttga
543121 atcgagtcct tcagctcgat tttttcattc aaatttagga cttcaccttc cactgaccgc
543181 acaccggtta tgaaatcttc gaggaatatt atagactcaa tgcttccgaa cattttcttc
543241 ataaactttg aaacttggtc gtggtgtttt ccagatccta tgatttttaa aagatcatcg
543301 ttgcctaaaa agtaaaacct tgggaattgt cttctttgtc tctctaaaaa tgtcgatagt
543361 gacgatttta tcatctttaa agaatctatc gttaacttca gagttgtgtc gaaatttgga
543421 atatgtatta cttcgattgt tgtgtcgagt tgaaacgctc ttgtggttat cattttatac
543481 tcactggtta agcttttaaa tttcgaagtt tcgagcggta agaagttttg aatgtccaag
543541 ttttcaccaa ggattccata caagtccaac cagtaaaact gtacttcaac ccaatttacc
543601 tgaatttcag ataattttgt cagtttagat tccaaatcca aacagtcttg ttcaaaaatc
543661 ttgtaataat tcgaagcttt catagaaact agctcctcta gatcctcttt acaggcttgc
543721 tccagtacat cccattccct cacaagcttg agtccactgg agtgctctat gacttcatat
543781 tgagcttcct tccaaaattt tttgattctg ttcagagact tttctataac aaattccttt
543841 tgggctcttt ctataatctt tgtaagtagt atttcattta aagttaaatt gaggaccatg
543901 acatctttaa gagaaaactc caatttatcc agtagatttt tttgtatctg tcttttacca
543961 atatcgcgga atatcatgtt ccaatgtcgt ggctttaaag caccatcctt taactccacc
544021 aagattttat ttacagaggt aagcatgtta acctgtgaaa atagcgattt atacatctca
544081 aattgtttga cagctctcgg cagttcatcc gccctccgaa gaaagtttgc caaatccgat
544141 tgaagtagca atacatctac tctacaccac ggcgtttcga aagttctttg aacatcttcc
544201 caaaggtttt taatgctcct ccaaactagg tcatacgttt tgacctcttc aaccacgtgt
544261 gttagctggt cattcaaaac aacggggatc agtaacattt ttgcagcggc tgcgacagag
544321 tgcatctttt tcttcaattt agtaattgat tcattgaaaa actctaggat tttaagtgct
544381 tcaggtggag ttaatgttgg agatattggt tttctgactg accaactttc gttcaaagat
544441 tgtgagagat tattgatatt ttcaacgcct tcttctagac tttttgctat aacaacgcga
544501 tgtttttgca actcttgttc aacatagctc aaactttgcc tcaacgaact aaaatcgtta
544561 tcgagctggt ctatatagac aaaatgcgat ggaaacctca ccttcagctt tgtaagcgcc
544621 ctcataacag acccaagcag cttgatttgg atatctcgtt cagtgagatg ccttttattt
544681 acattgacag cctcaatgat cactgttata ttctttaaag aggtaaaatt tatatccata
544741 tcctcgacag cttctctgtc cctgttcata tcttcatgca attttctagc atcgcgttca
544801 tatattgtta agagatgctt gctgacatat aagatccaag aatccatttt cgaacggata
544861 tgacgttgcg catcttctgt atgaagcact aagttctttg aaaagttatt tcggcttata
544921 attagatcga attttgactg agaatcaaga aggcctttta aaattccaaa gcatctttgt
544981 gtactgttat cgactacttc taaaaacgct tcctctgtaa tttgccagag aaattccatc
545041 ttttgccatt ctttgacgta agaatttatc ttacaatgta aattttgaac ctgttctata
545101 caattttgta tatcatcttt tagtttgatg actagcgaat taaaagtcag ggtagtggaa
545161 agaggatgat cagggtcatg caaaaaatta attaaaacaa ctttgtttaa aagagcctca
545221 atatccttca gtaaagaacg tttcatagca gctaacgatg gagatgatgt tattctacct
545281 tcattgaaac tgagtttcaa tacatgcttt gggaaatgca tttttttcaa atttaagcgt
545341 actttctcca agattatgct gataattaag ttattaaacg tggaaatatg gtcactaaca
545401 ttagtaagac ccttggtaaa aagattttca aaaatagctt gaatattgct tattatttcc
545461 tccacttcgt gcagatcatc agcagtaccg tcaaaagatt tcaggccaga aaattccttg
545521 gcaaactgag gctcggagtt tttcaatatt tgataatcag aaagaattcc atcaattgac
545581 ttttccaatc ttgctaggct gtgtaccgaa caggacattt cggaactttc ctcttgtaaa
545641 gattcccacg gcgttatcag aatttgttgt aatagtagcc atacagtttg cacgtttctc
545701 ttcagaaaga tgttcgtgta aaatgtatag gaaagtgatt tactaagtga aaaaaaagtt
545761 tgaattagtt caaccaagtt tattgccctc ggatacaaat acatgtaagt tctcgcaata
545821 cgtactatgt ggctaggcac ttgaaaagcc atataggtta aactccttaa ttccgagtaa
545881 gcagcagcta aggcaaaatc gaagttgact tttagttcat aatcatcctc attatttctt
545941 ataagcttta aaataggtgt cgtcaaaaga tttgctgttg ctttttcagg aaaattcccc
546001 aaccagtgaa ggaacacatc gtgaggattt gtttccttac gtagttgtac tatcgaagtt
546061 gatatcgaac gcccttcaag tgtgtcattc caattagaac caaaaagtgc ttcgagatac
546121 tgcactatat tgtcaatacg ggattgtaca ttcagaaagt aggaaattct tgcagatatg
546181 ggaggaatgt tatttaaagc ttccacgtgc agaattttag gcaagagctc taaaccagtc
546241 tccagttgcc gtatatcttt ttttatttca agtagcagta tctgttgatt ctctagtact
546301 tttactttta tcctaggaca aagttccatt aatggcttga attttactag ataacttaat
546361 ttttcggttg gacagtgatc agagtccata aaacttgcca acgtattttg taacttcttt
546421 tccaaatcga gcatgttttt actgaattca ctttcggctt gctccaattt caatcgaaaa
546481 ttcacggaaa tatcatggat ctgctcaaat ggatgataca atctctgtat ttcttcgtga
546541 taagtagaag gggatatact cttaatggtt tctgccaatg aaaaaaatcg cttgcgtgtg
546601 cttaaaattt catccaaagt agcctttacg gatgcacttg taaatgttag cttttgtata
546661 agtagctcct gtggtgctct tttcctaaga tcctctctta ttaaaagatt gacatcctgg
546721 acaatatcat cccattcttc tatcatgcct gctgattttt catataaacc caaaaaagaa
546781 ccatactcta gctgaaataa atctgaaaga ttacttagaa ttgcatccat gacttcttgt
546841 gaaattttgt ccatcagcac aacaaatctt tgaactggat aacctgaata tctgaacttc
546901 ttcaaagaag atgctaaaac aggaaatagt tcctgcaagt cctcaagatt gcttgcctgg
546961 cgaacctcat cgatagggat tgacgataga aattggttat atttatccgc tagcttaaat
547021 ttatctgaaa gtgaaccttc attcaataaa tttgttaaat tatgaaatct ctttgcgttt
547081 gttagaacgg atagacacac ctgaaattct tggctttgtg tttgttcaat taacgacttc
547141 agtacttcgt agaaattcga ccaaaactca acttcgtcta aaaaagaacc attttttata
547201 tctctgtcaa tggctaatgt ttgtttaaga accaaaaacc atttgtttgc aatgctttgt
547261 aaaatgttca aaaatctcat actttccaaa tcattactag gaaggtagtt tgcataatca
547321 tgtgaagtag ccccttttga tacagccaat ttgataatgc tagggaccat cgctaaaaga
547381 tctggcgttt caattgaggt atgtaactgt tgaaattgtt tagaaatgtc gtcaagtttc
547441 ctcctcgttt tatctatagt ttcgacagaa tatgtctttg tatctgattt tatcaattgg
547501 ccaaacacag acgatacgcc atgtgtgata attgaggcca ggttccccgc atttactgga
547561 ccaggtaagt atatggcact tatttgtgtt gcaatcggtt ctgcatccac aataacactt
547621 ctagatttaa taattaatag agtagaatac tttttattcg ccaagttggc atcatatata
547681 gcctcttcac caatgtctat tgtaactatt gttctatcca gctcttcaaa aaggaagaca
547741 aacaacgtgt cgaactctct cccatccaat aatcccaaaa aaaattgaaa ccgttcaagg
547801 tattgacaat gtagataatc aatgaatgct tgctcattct ctttgggaga attctttata
547861 cccgttacag tagctgcaac aaattctatc agctcattag caagtcttgc ctcattcttg
547921 cacattgcct aaaaaacgtt ttgacgtact ttccaattta agctctgaac gagtattatt
547981 gcccttctat gttctatgct ttctgttaat ttttatatgt aatgtttgtt tacctttcat
548041 tagcttattt attagaatcc gtacaatgcg accttccgcg catcaattcg ggatgatctg
548101 attaagtagt tatagcctta cgttaagacg acaaaagaca tgataagcat ccctcaaaag
548161 ttacagcaaa cttaagtcaa ataggtccaa aaatctccaa tagtaacgct ttttcatgaa
548221 tacactatta tttaagcgaa aaggtggcaa ttgtgggaac gaaagtaaca tagtttcgca
548281 gggatcgccc tcaagtagca atcttcctga atcacctggc actttagatg aaaagaatct
548341 tcccagattg cctactccat tcgctagaag cctttctacc attcctagtt atgagcagat
548401 gaaacgtaca aacaaactgc cagattatca cctaaagatt gttgttgtgg gagatggcgc
548461 tgtagggaag acgtgcctgc tgatatctta tgtccaagga acatttccga ctgattatat
548521 tcctactatt ttcgaaaatt atgtcacaaa catagaagga cccaacggtc aaattataga
548581 attggcatta tgggacactg ccggccaaga agagtatagt agacttagac cgctttcata
548641 tacgaatgca gatgtgctga tggtgtgcta ttctgttggt agtaagacat cgcttaaaaa
548701 tgtggaagat ctctggttcc cagaggttaa gcatttttgt ccttccactc caatcatgct
548761 agtcggcctt aaatcagatc tatatgaagc tgataacctt tcagatctgg tggaaccaag
548821 ttcagcagaa tccttggcca agcgtctggg ggcatttgca catattcaat gctcagcacg
548881 attgaaagaa aatatcgatg aagtatttga aactgccata cacacgttac tttccgattc
548941 attatatgct cccagagagc ctacacatac aatcaaaaat ccctttaaaa gaaataccac
549001 cagatcagat atcgattctt ctactggaga taccagcgtc tctatttccg gaacgaaaag
549061 attaagaaaa aacaagtgta ttataatgta agaataatga tgaagattat tctgttgccc
549121 attctgtacg cacttacaac atttgaaaag tggcaagaaa aaatacacac attttactat
549181 cttccgctat cttatttatc aagacgaaac aattagaacc tgatttaatt taacttccat
549241 ttttctgaat ctggtgtgat ataccgctcc aatatattcg aatttatccc aattttatca
549301 taataattca ttttaattcg atgtcataaa gtactaattc gatattaatc tagcctaatt
549361 acattaaata cttaataaaa gcttctgtga cataaaagta caaatctgtc attttatttt
549421 agaggaatag tttaggacaa agtcattatg tacgaacagt ttgaattttc tttttttttc
549481 ttcgaaaatt cagacaataa ggttaaatat aaagctcatc tcatctcatc gataaaacgc
549541 tggagtatta tcacatgcat gcgttgcttt tggaccgtac agaagtctat atttaaagct
549601 aggtttttcg cttgcagaaa ctttgtcaag aagcataatt ataaactaat cagcaccatg
549661 actggaagta ctgaaatggt accaccaaca atgaaacata ccgttgacaa caaaaggctt
549721 tcgtctcctt tgacagattc tggtaaccgc cggactaaga agccaaagtt gagaaagtac
549781 aaggccaaaa aggttgaaac aacttctccg atgggtgtcc tagaatttga agtgaacgat
549841 ttgttaaaat ctcaaaattt gtccagggag caggttctga acgatgttac ttcaattcta
549901 aatgataagt cctcaacaga tggacctatc gtcttacaat atcaccgaga ggtaaaaaat
549961 gtcaaggtct tagaaattac ttccaatggc aacgggttgg ctttgatcga taatcctgtt
550021 gaaacagaaa agaagcaagt tgttatcata ccgtttggcc tgcccggtga tgtagttaat
550081 atcaaagtct ttaagaccca cccttactat gtcgagagtg atttattaga cgtagtggaa
550141 aaatctccaa tgagaagaga tgatttaatt agggataaat atttcgggaa atcttcagga
550201 agtcaattag agttcttaac ttacgatgac caactagaat tgaaaagaaa aacaattatg
550261 aatgcctaca agttcttcgc accaaggtta gttgctgaaa aacttttacc cccatttgac
550321 accaccgtag cttccccttt acaatttggc tacaggacca aaattacgcc tcatttcgat
550381 atgccaaaaa gaaaacaaaa ggaactatca gtaaggcctc ctttaggatt tggtcaaaag
550441 ggtagacctc aatggagaaa agatactttg gatatcggcg gacatggttc gatattagat
550501 atcgatgaat gtgtgcttgc aactgaagtt ctcaacaaag gattgactaa tgaaagaaga
550561 aagtttgagc aagagtttaa aaactacaaa aaaggcgcga ctattttact gagagagaat
550621 accactattt tagacccttc caaaccaact ttagaacagt taaccgaaga agcctctagg
550681 gatgaaaatg gtgatataag ttatgtcgaa gtcgaagaca aaaagaacaa tgtcaggctg
550741 gctaaaactt gcgttaccaa tcctagacaa attgtcactg aatatgttga tggatatact
550801 tttaatttta gtgcgggtga gttttttcaa aataataact ctatcctgcc aatagtgacc
550861 aagtatgtcc gtgataactt gcaagctccc gctaaaggtg atgataataa aacaaagttt
550921 ctagtagatg cttattgtgg atcaggtctt ttcagtatat gcagctccaa gggcgtagat
550981 aaagtgattg gtgtagaaat ttccgctgac agtgtctctt ttgcagaaaa aaatgcaaag
551041 gcaaatggtg ttgaaaactg tagattcatc gttggaaagg ctgagaaact ctttgagtct
551101 attgatactc caagtgaaaa cacttccgtt atcttggatc caccacgcaa gggctgtgac
551161 gaattattcc taaagcaatt agccgcatat aatccagcca agattattta catatcgtgt
551221 aatgtccatt cccaggcacg tgatgtcgag tacttcctca aagaaacaga aaacggttcc
551281 gcccaccaga ttgaaagcat aagaggattt gatttctttc cacaaacgca ccacgttgag
551341 agtgtgtgta taatgaagag aatctaattg cacatataaa atatctatca ctatgtatat
551401 ctttctagag taaatgtctt cctgtacttt taaatccgta cattttgaaa attgaaaatg
551461 tatctcagat tcatttttca attcgaaatg aacgaaaatt acactaaaaa ggtaacgtgt
551521 agagtgatat tatgcacaac gattttttga aaatttcata tacgttattc taatgtttag
551581 tagagagttt agcggaagat ataaggtgat caggcgtaaa ttaaccacat acaaaccata
551641 gaaacatcat accaaaatgg aaaacgataa gggccaatta gtatgttcga gaaatctata
551701 agatttttta tattttaacg gatgaatgga aagtgcatgg ctgtttaaat aaatgtaaga
551761 aagatatcat aatgcaaaca aaacgtaggc atccgcaatg tatggaaaac atacttatgg
551821 ttaccgataa taagcaactc cgaaggtgcc atagaccagc tctgaatgca gcctacaaaa
551881 gttgagcaat ttctgacaaa attcttcgat tactttcttc acatgtatta aatcatcact
551941 caccaccacc aacaatgtgt tttttaaact agcataacta acaaagattt gttttacatc
552001 aggtcgaact ttacgttcca agaaaatgtt ctgctaccaa cagaatcatc aaggctgatg
552061 accacgcatc tgttcaaatc aacgtcgcta aggttgatga agaaggacgt gctatcccag
552121 gtgagtacgt tacctacgct ttgtccggtt acgttagatc cagaggtgaa tctgatgatt
552181 ctttgaaccg tttggctcaa aacgatggtt tgttaaagaa cgtctggtct tactcacgtt
552241 aagagaaaag aaaaagagga ttcgatttaa gcttcatatc gttcagacta ataggtaact
552301 gacgattttt ctcttcatta ccaacttttc accatatgtt ctaattcgtc ggattttcga
552361 tgaagcgttt taggtactct ataggtattt aggttataat aatatattgt atttttagac
552421 aaccggaacc tgtttaattt gaagagtcat tgtattcttg gctattctgt ttaaagtttt
552481 gcagtgtgga gtccctgaga aacccccgag caaaaaaaag accccaaaac cccgtaaata
552541 ttactactct acttgtgtgt tatacatttt caggagtcaa aacgtactaa caaccttaag
552601 cttgcttaaa gaggtgctat atatgtcgat aagaagcaga gtataagggt gcctgaaaat
552661 gtttgttgct tgtaagctat gcctttactc ttgacttact tcaatattgt tggcaattcg
552721 tggtggagac ttagtaggga ttctattttc gcgtactagt gtgatgggaa tgtataagaa
552781 gctggctatt gccacattgc tctattccgc agattattta ccaggtgtgt ttgcccttgg
552841 tcaccaagtg aataaattgt tagaggaagc aggcaaaaaa ggcgacattg aaacatgcct
552901 tattgtgacg acctctctat ttaatggcac tttaagcgag ctagccaaga atattttaca
552961 atcaatatac accaaaattg tgttggtaga gcctttaaat tgccaagaag aaagcataca
553021 gaagaatagt gagaatttag ctcttttgga aagacctgaa ttatcctttg ccttaatcaa
553081 agcaagacta tgggaattaa ctcagttcga acaagttctt tacttggatt ccgacacttt
553141 acctctgaat aaagaatttt taaagttgtt tgacattatg tctaaacaaa ccacgtcaca
553201 agtgggtgct attgctgata tcggctggcc tgatatgttc aatagcggtg tcatgatgct
553261 aataccggat gctgatactg catccgtttt acaaaattat atttttgaaa acacttcaat
553321 tgatggttct gaccagggca ttttaaacca gttcttcaat caaaattgtt gcactgatga
553381 gctagttaaa gacagtttct ctcgagaatg ggtacagtta tcatttacgt ataacgtaac
553441 tattcctaat ttaggctacc aatcttcacc tgctatgaat tactttaaac ctagcattaa
553501 gttgattcat ttcattggga aacacaagcc atggtcattg tggtcccaaa agaatttcat
553561 taaaaacgag tatcatgatc aatggaatga ggtatacgag gaatttaagg aagaacatca
553621 attaaataac gaagtttcga agccaaagat tagtgattcc gataaaactg agactcctga
553681 aacgataacc ccagtggatg cccctccatc gaacgaaccc actacgaatc aagagatcga
553741 cacaattagt acagtggaag aaaacgtgga caaccagaac gccgagcctg ttcctaactc
553801 ggatcatagc cctgctccta accctgtccc attggatttt accaagtggt taacaacctt
553861 tattaacaaa gatcacttga ctaatcagcc agtaaatgaa agcagagaat attcgaaaga
553921 gaatgataac aatataatca atagcagttc aaaccgcgac caagaaagtc ctccaaatag
553981 tactcaggaa ctaaacagct cttatagcgt tgtgagtact caagctgata gcgatgagca
554041 ccaaaatgca gaagaggagg atagtacgac agataacgct tcaaattctg gagaagaaag
554101 ccacctcgat gatataagca cggccgcttc ttccaataac aatgtaagta atcaaccaga
554161 tggcaaaaat tttagcaatt ctaaagaaaa taatatcagt gtcgaatcta gcccttcaaa
554221 tccagaacag aaaaggtcaa ctgacaatat acaaaaacca agtgtttcta ctaatgactt
554281 accagacgac gtagaaccac atacctctgt tgatgacaat atacagtact tagaaaaaga
554341 caaggaaggt tatgaagaat ttcttccgga cgtgtacgag tcaaatgcaa tcgataacga
554401 agaagaattt tttgatgacg atgcaagaga tgctaccgaa ggagaaacga agacgagtgc
554461 agttgcagat aaacaggagg atatgaaact tacagcagag gaaaccaacc aaccgcaaca
554521 agaaatgccc aacttcaaat ttgactggga ggactctgat tatctatcca aagtagagag
554581 gtgtttccct gatgatattt ttgagtatgc agtagagtaa acttccacgc acatattagg
554641 aaaattaaaa gacatatcta tgtaaagacc ttttcgacta tacaaaaatg cataactatt
554701 ctatatacat tcaaactcga aatttacttt aaaggtttat cagcaacaac atccgatgct
554761 tgctgtttat cttttctcac ctcacaacgt ttatagtgac tgaaaaattt ttgcattctc
554821 acctcgtcta ttgaatgatg tgctaagaac ttgagctaac atcacagaac aaaggtatga
554881 atatacgcag ccctgacatt tgtagatttt ttatttggtc tctagtcttt tcttttctta
554941 ttttataaca aattcgttaa acggcctcct tctaattata tacaagatgt ctgaaggtat
555001 tactgatatt gaagaatccc aaattcaaac caactatgac aaggttgtct acaagttcga
555061 tgatatggaa ttggacgaaa acttgttaag aggtgttttc ggttacggtt tcgaagaacc
555121 atctgccatt caacaacgtg ccatcatgcc tattattgaa ggtcacgatg tcttggctca
555181 agctcaatct ggtactggta agaccggtac cttttccatt gctgctttgc aaagaattga
555241 cacctctgtc aaggctcctc aagctttgat gttggctcca actagagaat tggctttgca
555301 aatccaaaag gttgtcatgg ctttggcttt ccacatggac atcaaggtcc acgcttgtat
555361 cggtggtact tcctttgttg aagacgctga aggtttgaga gatgctcaaa tcgtcgttgg
555421 tactccaggt cgtgtttttg acaacatcca aagacgtaga ttcagaactg acaagatcaa
555481 gatgttcatc ttagatgaag ctgatgaaat gttgtcttct ggtttcaagg aacaaatcta
555541 ccaaattttc accttacttc caccaaccac tcaagttgtt ctattgtccg ccaccatgcc
555601 aaatgacgtc ttggaagtta ccaccaaatt tatgagaaac ccagttagaa ttttggttaa
555661 gaaggatgaa ttgactttgg aaggtatcaa acaattctac gttaatgttg aagaagaaga
555721 atacaaatac gagtgtttga ccgatttata cgactctatc tccgttactc aagctgtcat
555781 cttctgtaac accagaagaa aggtcgaaga attgaccact aagttaagaa acgacaaatt
555841 taccgtttct gccatctact ctgatttacc acaacaagaa agagacacca tcatgaagga
555901 attcagaagt ggttcttcca gaattttgat ctccactgat ttgttggcta gaggtatcga
555961 tgtccaacaa gtttctttgg ttattaacta cgacttacca gctaacaaag aaaactatat
556021 tcacagaatc ggtagaggtg gtcgtttcgg tagaaagggt gttgccatca actttgttac
556081 taacgaagac gttggcgcta tgagagaact agaaaagttc tactccactc aaattgaaga
556141 attgccatcc gacatcgcta ctttgttgaa ctaagggaga caaaaacttc ttaaaaaagt
556201 atcttgtgag gctatcttga taacgtaaca tatatttcta aaaagttata tatgcttttt
556261 gtatttaatt tgtttttctt tttacattcc tattattctt caaagtccaa aagactctcg
556321 gcacgaaggt tgaaataccc tatactaatt gtttgctttg tctttttgta tatatccgaa
556381 cgtatctatc tgaaattttt caaatttata aaaaataata tatataaaag gaaaaaaaaa
556441 aaaatcgatg ccctactaat agagattgga gctgaaaaga aaaagtgtac atcaaacgct
556501 atatctcgag gtttgggatg gttgagtcaa atgatattat aaaaagtggg ctggcagaga
556561 aagcactaaa ggctctaatt ttacaatgtg aagagaaccc atctttaaaa aatgataagg
556621 acatacacat aatcatcaac acgggcaaaa aaatgggcat aaacagggac aacatccccc
556681 gtattattcc attaacaaag tacaagctat ttaaaccaag ggacctaaac atattactca
556741 ttaccaagga tccctctgcc ttgtatagag aaactttgac gaaagacgag catacgtcgg
556801 aattattcaa ggaaattata agtgtcaaga acttgagacg tagattcaaa gggagtaaac
556861 tgacccaact ttataaagat tttgacttgg tcgttgccga ttacagagtt caccacttac
556921 ttccggaggt tcttggtagc agattttatc acggtagtaa aaaattgcca tacatgatcc
556981 gcatgtcgaa agaagtaaaa ttgaagcgtc aacaaatggt cgaaaaatgt gaccccattt
557041 acgtgagagc acaattgaga agtatatgta agaatacctc atacattccc aataatgaca
557101 actgcttaag cgtcagggtc ggttatattc aaaaacactc cataccagaa attttgcaaa
557161 acatccaaga tacaataaac tttctcactg ataaaagtaa gagaccgcaa ggcggcgtca
557221 ttaaaggagg aataatatct atatttgtca agaccagtaa cagtactagt ttgcctatat
557281 atcagttttc agaggctaga gaaaatcaga aaaatgaaga tctgagtgat attaaattgt
557341 aaaattaaag catcatcttt taaatacggt atttaaacac tcccaatgaa aaagcgtgat
557401 tttgtctaac taattatagc attaataaag tgttttaaac tttaattcct ttcaagaatt
557461 tgcaagatta tagaaattta gtaagcgaaa aaaaaaaaga aaaaaaaaag aacagacacc
557521 ctataaaaat agaataaaca taataagcca ccatttgcct gtctgatgat attcttgatt
557581 ctttatatct cttcaggtat gtgacaccta tacatgcaac gctttttttg cgttttttct
557641 atacaatagt tgtttattta aaagcgtagg agcttcatgc aaatctgcaa ggtatttctt
557701 acacaggtta aaaaactact ttttgttagt cttctatttt gcttgatagc tcaaacatgt
557761 tggcttgcac ttgtaccata tcagagacag ctgagcctag attcgtattt ttttagaaga
557821 tctcgagaag tttcatcgag atatgatttt acaaggaggc gacatatgaa tcagacgctg
557881 aagctatcta gcaacactta taatgatgaa ccactaaaca agaccaaggg aataaaaaat
557941 caaagagaaa atgctacatt gttaatgctt gtgcgtaatt gggaactttc gggggcactc
558001 cgttccatga gatcactaga agaccgtttc aataaaaact accagtatga ctggacattt
558061 cttaatgatg tcccatttga tcaagagttc atcgaagcca ccacagccat ggctagtggt
558121 agaacgcaat acgctttaat ccctgcggag gactggaaca ggccatcttg gatcaacgaa
558181 actctatttg aagaggcttt acaattaatg gaggaaaaaa atatcttgta cggtgggtca
558241 aagtcatata gaaatatgtg ccgatttaat tctggatttt tctttagaca aaagatatta
558301 gatccgtacg atttttattt cagagttgag ccagatgtag agtatttttg cgattttccc
558361 tacgatccat tcaaggtgat gaggcagaac aataagaaat atggctttgt gataactatg
558421 tatgaatacg aagatacaat tccgagccta tgggaagctg tagaagaata tctcgaagaa
558481 acagagtcag cagatattga catggaaagc aacgctttcg ggttcgtatc aaatttcgac
558541 ttcatcggta aatcttttgg tgtcatcgat agtaacagcg gctataattt atgtcatttt
558601 tggacaaatt ttgaaattgg cgatttgaac tttttcagaa gtgagaaata cattagattt
558661 ttcgagtact tggattcaaa gggcggtttt tactatgaaa ggtggggaga tgcaccagtt
558721 cattcgattg ctgcctcact tcttttgaaa aaagacgaaa tcatccattt tgatgaatta
558781 ggctataagc atatgccttt tggcacgtgt ccatctgcat actacctgag acttcaacaa
558841 agatgtcttt gtgatagcaa tcacccagac aatattgatc tcaatgtcat cagctgcctg
558901 agaagatggt ggaaggacgg cagcggtaaa tacttcctca aacacgattc atagcgagaa
558961 aagcgtgtat ccgcatacta taaatacgta tatataacaa agtaaccatc aagaaagatg
559021 ttccatacct caggtcatca ccatttcatg ggtcgcttaa ccgaaaatat cagaagcaac
559081 ctctaacggc gatggtttta aagatggatt acctcagcac caacagttac actattcgga
559141 accgaagatt tatctacgat actcattatc ctttctctat ctcaccctga aataatttat
559201 taaaaataaa ctatgccaaa gaagagaaaa gagaaaaatt taaaaaaaac gagagccatt
559261 gcaacagttt tggaagtaag aataggttga aaattagtca aaaagacaaa tccggctcct
559321 ataaaccatc aaacaatagg ctccctaaag catcacaaat tgttatgctt tcttttaaga
559381 gaaatgtttt ttaaagcatc aaaggtccag ggcaagaaaa attctttctg gtagcaaatg
559441 ctatagttca cggcttttat agtcaaaatg ttatatgcga gaagaaaaag aaaagcgcga
559501 gcttacttcg ggtaagaagt tcacttacga atcagggcaa aagagctaat aagaagtgaa
559561 ctagttacat aaccgtgtgc tctgtagaac acgagaaagc tgttacacag aactgtttta
559621 taccaagtag ttcgttcgat ttggaaaaga gagtagtctt ttgcgatgag taaaaacagg
559681 gaccctctac tggctaattt gaacgctttc aaaagcaaag tgaagtctgc cccggtgatc
559741 gcacccgcta aagttggaca gaagaagacc aatgacacag tgattactat agatggaaac
559801 actaggaaga ggacggcctc cgaacgtgcg caagaaaaca ctttgaactc tgcgaaaaat
559861 cctgtgttag tggatatcaa gaaagaagct gggagcaata gctctaatgc tatttcatta
559921 gatgacgacg atgacgacga agattttggt agctctcctt caaaaaaagt aaggcctggc
559981 tctattgctg cagccgcttt acaagcaaat caaacagata tttccaagag tcacgattct
560041 tcaaagttgc tttgggcgac tgaatacatt caaaagaaag gtaagcccgt tttggtgaat
560101 gagttattgg actacttgtc aatgaaaaaa gatgacaagg ttattgagct tttaaaaaaa
560161 ttagatagaa tagagtttga ccccaagaag gggactttca aatacctttc cacctacgat
560221 gtccattccc cttcggaact gctgaagttg ttacgttcac aagtaacatt caaaggtatt
560281 tcctgcaaag acttgaaaga cggttggcca caatgcgatg aaacgattaa ccaactggag
560341 gaagacagca aaattttggt gttaagaact aaaaaggata aaactccaag atacgtttgg
560401 tataacagcg gtggtaactt gaaatgtatt gacgaggagt ttgttaaaat gtgggaaaat
560461 gtgcaattac cgcaatttgc agaattgcca agaaagctgc aagatttagg tctaaagcct
560521 gctagtgtcg atcctgctac tatcaaaaga caaacaaaga gagttgaagt taaaaagaag
560581 agacaaagaa agggtaagat tactaacact catatgaccg gtatcttgaa agattattcc
560641 catagagtat gaggttgttt tgattaaatc attttcgttt gcatattagg ttaaagagac
560701 tgtgattata tatacatgca cgttagggtg cagcatacaa ctcagcttta tagtctacaa
560761 cgtatttata acgagcattg gaaacaggtt acaggacacc aaagggtttg ggtttccaat
560821 tttgaaccct tgaccaattt tttactggtg tagctctgtt ctcctcttgt ttattttttt
560881 tacctactgt tccgaaactg ctcattctct gtttcaaaga cgccaaatcg cctagtatat
560941 cattggtatc agcctttaat gccggactca cttccttctt caatggaacg gaatcttttt
561001 ccgcaggaat aaaatcatac agctttattt caccttcatt aaaccttaat gataaattgt
561061 ctatgttttc cttcagtttt gcctcgattt ccactgtgct atcaatttgt tttctccgtt
561121 ttttgtttct ccatgagtta ccagtaattt tttcagtctc tagtttggcc agcatagatt
561181 ggcaaaaata caatatcaag tatgacgcat tttcatcaat aagtttctcc caattttgcc
561241 atttattttt aaaattttta ttgttaaggt tatttataat aacatctaac agcctttttt
561301 gtagttcttt ccaggcattg aatttccttt ttaaaattgt cgttatatta ctatcatctt
561361 gttgggttct gtaattccta gctacccact caatgacctt ccaatcaaaa ttgttcaaat
561421 taagcattaa aactttgagt aaaagtgggt cataattgtt aaaaaatttc tcaagaacca
561481 cattgtgata aatggataat ttccaaagtt cttgccattg acgcaaattt tccctgatca
561541 tagtttctga tgaacttgcg tgtgaacttt tcctcttttc ggcatcatag ttcaccaaat
561601 tatccccaga aaagttacta cttgtaatta aactatcgtt tgcattctcc cacacccatt
561661 tgtattccag aaactcgttt ctaagtcgct tccatttatc aagtgtttta gttaatgact
561721 ccatatattt ctccagttta tcatttcttc tgtatccgta accggtatca tcatcatcgt
561781 catcatcatc cctgtcatct tctaattcct catcgttcca gtagtgatca tatagccaag
561841 ataacgcttc attggcggcc caacgaagca tttctaatcc aggtaaatct ctctcatgtg
561901 taccccagtg tctcaaatca acaaaccagg acggcagtcc aattttagca gctaatgtgt
561961 gtaagggaat agcgaactga gattgttgcg ttggatccaa taagccattg acaaaccgaa
562021 tcaaagccat tacatacgat aaccggatag gaatagaatc ctgatgtact cctaaacacg
562081 cttccttttc gtctagcaat accgcacatg ttatttgtgc tgtagagtcc accacgtgag
562141 gtaaatattg ggaacccttt agtcggtagc tctgtactct ttgcactgca cgctgtcgct
562201 tatcttcaat ggttcctttg cttttcgggt aaaaccaaag tttcagctcc tctagttcag
562261 caaaatccct ccatggaacg attcgtggtg gtatcattag attgcccttt tttcattgct
562321 ttctagaaat gacttttgtt taagctaatt taggcattct taggtatttt tttcactctt
562381 tctgcgactg cgatgagctt attaatcttt cacattcggg taattttttg cataacaata
562441 agtcatgaat ttattgttgc gattttgcag tgttatgagt ctatgaagag aagaaagaaa
562501 ctagaaacca attgatacca gactttagtt gacaactgat ctcataatgg gatatgactc
562561 ccaagttagg acaaaaaaac gacatcgaat tactgtagta tgcacaaatt gcaaaaaaag
562621 gaaaagtaag tgcgatcgaa cgaaaccatg tggaacatgt gtacgactgg gagatgtgga
562681 cagctgtgtc tatctcaccg atagctctgg acaacctgaa agcagtcctt cattgaatga
562741 tgctgaccct ctgaggaaac aatcaactcc tgcggaacga ataagtccag gtttcattaa
562801 gaaaagaaga tcgtcacaga caagacaaga cgaagatcac tggcaaagag tacgagaact
562861 tgaaaatcaa tcatcacttt attatctacc aattcatgaa gaaactccat tttttattga
562921 cctcatccct aatgggtttt atttagagac caaaaggtct gctgataatt tatttggtct
562981 gttcacggat agagcaattg aaaatcgcga cccctatctc caagcaatgg taacatttag
563041 aagtatcgca atcaaaaaaa tgatggataa attgggaagc aacggcaata atgtgaaaaa
563101 tggaagcttg cctaaatctt tcgaagcttt atccactttc gatgctgatg acgaacgcca
563161 cattagcgat gatgttgttg gtaagggcaa taacttccgc atgcatcaga ctattcacaa
563221 atcattgttt aacaaattcg ctcaatacag agaaaataat gctaaaaaat tcagctcaga
563281 aactatatta gcaaaggatt atttgcctcc tttaaaaata cttgaaagtg aggttttagc
563341 actttttgaa gaaaaaattt acaatatgat accgattttc gatatgaaag ttttgcgtca
563401 tgaaataacg atattttatc aaaatatagt cgagaaaggg aatccaattt ctataaaaca
563461 ctacgatcat atggttttct gcataatctt gttgattatt aaaatatgcc gactttctgt
563521 ccagttttcg aagctaactc catatatata cccggttctt caagaaattg atacctctaa
563581 gtttttggct cttgttaaac actatttgtt cgagacgaag gtcctcagaa aatgtaattt
563641 attacagttg caatgtctca tattactaag gttcttgcac tggtgtgccc ctgaagatgg
563701 cgatggaccc gaaactcaat attgtcaaat cttaatgggg acaataatat catcatgtaa
563761 agaaatgggc attaactggt attgcttctc tcatccagaa aaatattcat ttaaaataaa
563821 ccgacatacg aggccttcat acgatataat gaaacctagc gattacattt cagttttcag
563881 aaagatatgg agttatgttt tattttggga caggaagatg tgttttatta gcggtgaaga
563941 atgtcaaatt gggaaaacct tgcagtgcca tttcaaagaa gaagcagata cacccacatg
564001 gtatatacga atgttaaccc tggataactt gatgaaaaag ataaacgata cgttgaacga
564061 tgatccagga aaggtagatt tgaacttgtt gcaccgacta ataaatgatt taaaaagaaa
564121 ctttcatatt ttaaaaagcc tgtcgaaaaa cgaaaaagaa acaatgcgtc attttgattt
564181 cgaaatggaa tggataatag atttattctc actaagtttg ctgcacggag aaatgatctt
564241 ttatgaatat gactgcaata ttacaaaatt ttataagagt ttccaagatt tgtgggatat
564301 ggtcattcat atctcagaga agtgctacaa ttactttttt aacagtgatg ccttagaggt
564361 ggattcattg acaaagtttt ataccaatag aatcgtggaa attgtcgcaa acaaagtttt
564421 ggtcattgtt ccggcattca ttctcagagg agaccgcttc aaaacaattc agtacgccga
564481 caagaagaaa atgatagaat ttctttacgg ggtctcgtct gtgtatttta acgaatttgg
564541 ctttgagtac tatcgttgtt ttagaaaaat gttcaccgct aaaattgcct acaagatctt
564601 gaatcgctca tgtgaaaaag atgcatggag aattatttta aaatttttgc tgaatgaatt
564661 gaaactagaa gataacggtg atagttatat agattacaac gatatgagat taaatgacat
564721 ctgtccaata atactagaat ttcaggagac agtacaaaaa tatgatgggt ataggccaga
564781 tattctaagt atatggaaca atgagtttta tcccataggt aaatacaacg atgatatgac
564841 aggatttaag tttcaaatgc gcataaagga aatgcaagaa ttcttggata tggagaaata
564901 ttccgacagg tttaatattt tttcatcctt ttatgatcac gccagttcac aattagctaa
564961 acatactgaa gttgatacca acataagcat tacgaatgaa caagtagctg aaattccgca
565021 aaaagaacta ctacaacaac ctttagcacc cgctttgcct gttaatgatt taattgtctc
565081 agagtttgac gtgattgaag atatttttga tcctgtggat ttcgtatcat ttttttaaag
565141 tcagagataa aagagacgta taggacatat acaatattca tacctttcac ttcctcccta
565201 tttcattcga attatttagt agcgttatat atcgcactac tttattcata tatgtatata
565261 tacagagtct gagaagaagg aaaagatcac acgttcaatc acaaaaattc tttggctttc
565321 tttgcgtaag cgtgacaatc tcttaaccat tgcttatatt cctttaagga acctatcttt
565381 tcaccgtaat aatctggaac aggattactg aaactttgag aagaggcatc gaccctgtta
565441 ttgatgatat gttttagaaa ctctttattt ttgttgttga actgtgccaa ttgttggtta
565501 tgggaaagtt tgaaaacttg cgaaccaact atcggaccca acaagtagcc tagtgcacca
565561 gaggctatta tcccagctga aattacagtt aatgggtcga atccgaatag catttgagtc
565621 gggtctattt ccattgtgga aaggtaagcc catgaaacgt tacagcccaa aagagcagta
565681 aacagcgaag aaccaacatt gattctacgc tgctgtttcc tcaatttgaa aaaatcagac
565741 catgtcaaga tactggagtc ttgaagggat gcgggctgag aatatgatct taagggtaag
565801 gttgtagcag tcgagcgcaa tgccgcagcg gtgacagaag gttgactagc gaacagtctt
565861 tgcgatgaca atctaatggc actggtaaac attttgaaga ggcggacaat gttttctgaa
565921 tgtttttaac acttctttga acatagtttc ccttatgata taccattgta tggctttcca
565981 tttttcatag acgtaccgta caaacgtatt agatgatatt cagaaaaaag cataagccta
566041 aataataata aatataataa atagataaat aatacgaaat ataaccaata aataatatct
566101 ttcctcagtg acctataaac cttgttcctc taaagtcttg aaaataaatg gactgggcgc
566161 gtctttaggg aaagtgatac cgttctccaa cagtttttca aaagctttgg aaaaatcctt
566221 gaagaacttg tcctggtcat tagcgtattc tttcacaatg cttaagtact tgggatcctg
566281 aatcaaagaa taatcagtgg gcagcatcat gtagccgctc ttagagtccc actgttcgtt
566341 gttcgcgtcg ttcttttcca atttccagtc ttcattcagc aagttcaagt aaaactcatt
566401 ggtaaagacg ttgttagcgg ctccccatgg cccttcgtat ccagagttct tcaagtgggt
566461 cttgcccaga gcgtgagccc ccataagagc aactacttct ctgtcattca tattaagtct
566521 ttgaaaaaat gttctgacat agtcagcgtc tttatcagcg tcaggcagtc tcccgttgtc
566581 aggggtagta tcctctggcg tgtcgactct accacatctc catggaatct tgggaccctg
566641 catttcctgc acggcagtga caccccctag actgaacaga tcacccgagg agatccaggg
566701 aaactctttg tgaatgggct ccaggaactt gaagccattc tgcaagcccg cattggatgg
566761 atcgttaaac tcctttttga atctgtatgt accaccgtat gacccgcctg tattgtcgtg
566821 cttgtcccag gtccctgaag tgtgccaagc aagacggact aatacgggcc catagcctat
566881 atagttgtca tattcgtcat cttccctcag cttgagtgca atcgcattgt acaccttttg
566941 gaagtcctcg tatgacctcc ctttttcgac agaggcgaca tgaacgagcg gtgtagtgga
567001 agccaaagca gctgccttcc cccagttgtt ccatccgtgg ttactaccac ccccgggaga
567061 agacgatgat ctcttttggg attgcgagta agcaaaagtt gcagcagcag cagcagcagc
567121 agcagcggag aacaggtaga gagacctctt atgggcggtt ctgcccagtg aaggtaaaag
567181 cctaacagca gtagtcataa ttgtagatat acgtgtgtgt ttgcgtctgc atgaatgcga
567241 aattcatgtt cttgagttag cgagcgtgta caatagtctc tgcttaagta cttttcgctc
567301 cagggtcctt tcctaaattg gtaacagccg gcttgggccg gcccctggat gccaagagag
567361 tcatattact cagtactcag gaccaaataa ctcatcgctg tcgttggtaa agaaaactac
567421 aaatctgggc ctgaccatgg tttacgaaat tcctgacaaa gcaggatatt ctttggcttt
567481 ggaatttcca ttggcgagat ctagctgcgg gagaaatcat cccgacatta tgtaagctac
567541 ataggtcgct gaagtgtagt cgccacacgg cagcgctaaa tgataactag taattggtgt
567601 ggagcgacca cattttcgca tcgatccaag ctcgtctttt ggctttcttg gctattctta
567661 ctagttatat tgaattatta cagctcttgc tggaacacca gtaacccgcc gttgctccgc
567721 attttcgaag taaatggctc actttgattg taaggttgag aggagtaata aagaggggag
567781 agaaaagagg agagaccctg aagaagtggc agcttgagta taagatagtg tcttttcgtg
567841 cttcgtcgct agagcaaaat tctactttca catctaataa agccgattaa tcgatcagtt
567901 attgctccct ttcctttatg tctgctcccg ctgccgatca taacgctgcc aaacctattc
567961 ctcatgtacc tcaagcgtcc cgacggtaca aaaattcata caatggattc gtatacaata
568021 tacatacatg gctgtatgat gtgtctgtat ttctgtttaa tattttgttc actattttct
568081 tcagagaaat taaggtacgt ggtgcatata acgttcccga agttggggtg ccaaccatcc
568141 ttgtgtgtgc ccctcatgca aatcagttca tcgacccggc tttggtaatg tcgcaaaccc
568201 gtttgctgaa gacatcagcg ggaaagtccc gatccagaat gccttgtttt gttactgctg
568261 agtcgagttt taagaaaaga tttatctctt tctttggtca cgcaatgggc ggtattcccg
568321 tgcctagaat tcaggacaac ttgaagccag tggatgagaa tcttgagatt tacgctccgg
568381 acttgaagaa ccacccggaa atcatcaagg gccgctccaa gaacccacag actacaccag
568441 tgaactttac gaaaaggttt tctgccaagt ccttgcttgg attgcccgac tacttaagta
568501 atgctcaaat caaggaaatc ccggatgatg aaacgataat cttgtcctct ccattcagaa
568561 catcgaaatc aaaagtggtg gagctcttga ctaatggtac taattttaaa tatgcagaga
568621 aaatcgacaa tacggaaact ttccagagtg tttttgatca cttgcatacg aagggctgtg
568681 taggtatttt ccccgagggt ggttctcatg accgtccttc gttactaccc atcaaggcag
568741 gtgttgccat tatggctctg ggcgcagtag ccgctgatcc taccatgaaa gttgctgttg
568801 taccctgtgg tttgcattat ttccacagaa ataaattcag atctagagct gttttagaat
568861 acggcgaacc tatagtggtg gatgggaaat atggcgaaat gtataaggac tccccacgtg
568921 agaccgtttc caaactacta aaaaagatca ccaattcttt gttttctgtt accgaaaatg
568981 ctccagatta cgatactttg atggtcattc aggctgccag aagactatat caaccggtaa
569041 aagtcaggct acctttgcct gccattgtag aaatcaacag aaggttactt ttcggttatt
569101 ccaagtttaa agatgatcca agaattattc acttaaaaaa actggtatat gactacaaca
569161 ggaaattaga ttcagtgggt ttaaaagacc atcaggtgat gcaattaaaa actaccaaat
569221 tagaagcatt gaggtgcttt gtaactttga tcgttcgatt gattaaattt tctgtctttg
569281 ctatactatc gttaccgggt tctattctct tcactccaat tttcattatt tgtcgcgtat
569341 actcagaaaa gaaggccaaa gagggtttaa agaaatcatt ggttaaaatt aagggtaccg
569401 atttgttggc cacatggaaa cttatcgtgg cgttaatatt ggcaccaatt ttatacgtta
569461 cttactcgat cttgttgatt attttggcaa gaaaacaaca ctattgtcgc atctgggttc
569521 cttccaataa cgcattcata caatttgtct atttttatgc gttattggtt ttcaccacgt
569581 attcctcttt aaagaccggt gaaatcggtg ttgacctttt caaatcttta agaccacttt
569641 ttgtttctat tgtttacccc ggtaagaaga tcgaagaaat ccaaacaaca agaaagaatt
569701 taagtctaga gttgactgct gtttgtaacg atttaggacc tttggttttc cctgattacg
569761 ataaattagc gactgagata ttctctaaga gagacggtta tgatgtctct tctgatgcag
569821 agtcttctat aagtcgtatg agtgtacaat ctagaagccg ctcttcttct atacattcta
569881 ttggctcgct agcttctaac gccctatcaa gagtgaattc aagaggctcg ttgaccgata
569941 ttccaatttt ttctgatgca aagcaaggtc aatggaaaag tgaaggtgaa actagtgagg
570001 atgaggatga atttgatgag aaaaatcctg ccatagtaca aaccgcacga agttctgatc
570061 taaataagga aaacagtcgc aacacaaata tatcttcgaa gattgcttcg ctggtaagac
570121 agaaaagaga acacgaaaag aaagaatgat caaaaaatag aaaaataaaa aaaaaagcat
570181 ttgacaatgt ttgtaaataa tataatatga aagtaactac tgaacaaaaa cattaaggat
570241 aacatttcta cgtaggaaaa taatgtatac ctaaataacg acaccaataa taacaaaaat
570301 cacgaaaaaa aaaagcttac atgtccacta atcttcgccg atcggtattt cgtcttttaa
570361 aattctattt aacttaacct tgatctccgt ctgagagtct cctctcaaga tatccgacac
570421 aaaccagaca tcacaatcca gctgcaccat ttcaagtgac cctttcaaaa caccacacaa
570481 tatattggaa taccagagcg atttcatagc gtccatgggt aactccacaa agtcagccaa
570541 tgggttttca tccaaaatca atgaaaaagt atccttgtta tgcgaccagt tcgttatgtt
570601 gggtgtgatg tttaaaaata ttttgaatgc acacttactt agtacttcgc ttgtcttcac
570661 taaattctca cagcgtggca atgccgttct agccaagaaa tcctcaataa gtctacaccc
570721 aatattatat cccatgctat acaaatgatc attcactttg ttaaagtccc gttcataatc
570781 ttggcacaat tgtgccacta tggacccata tgttagcgta aataattctg tattaatttt
570841 ttctgtttta tttttccaga tctcttctcc catggccttc aaagacctcg attgcgtggt
570901 agaaaccatt tttgacccag ttttggttat caatgaacac ttgaagcttt actctgcatt
570961 cccatctcta tagctatggg taatcacagc tacgatcact tactctgtta ttattatatt
571021 aagttcaatg ttggccaaac cgggtaacat gtaacacttt caggttggcc ttacctttgg
571081 cttggagttt cgcaagtttt caaatttttg gctcctgctg tcaaggtgca tagaatagcg
571141 cttatttatc tatttatatc caagatgtac aatcctcgtt ctctgagtcc aacatatttg
571201 ctcgcaactg tagaaatcac aactacagca acagtaaaga tatcattttc tattttcgtt
571261 attggtttct cgaccttttt atatacgata cgtcaaactt gaatcatttt atacgttttt
571321 ctctttctag aaatgccatt atgcacgtga cattacaaat tgtggtgaaa aaaggctctc
571381 ataataaact gtgaacggac tcataatgaa atttgcttca ctatgtgaat catcgctaat
571441 aaactcgcta caaaagtcga gtatgcttaa gtcaaaaaaa tgatatatat atataattta
571501 cttatgtgtt tctgcaaagt tgtaggcttc atttagaatt gctcagatat tccatcccaa
571561 ttaaaaaaag cacggataga gtgataaata aactaagaaa atttcaaaag aatggtacga
571621 gacttagtga cattgccttc atcactgccc ttgattactg ctggttttgc tactgatcag
571681 gttcatttgc ttattggtac agggtccacg gactcagtaa gcgtttgtaa gaatagaatc
571741 cactccattt tgaatgctgg tggtaatccc atagtagtga atccctcgtc accaagccat
571801 actaaacaat tacaattgga atttggtaag tttgcaaagt tcgaaatagt agaaagggag
571861 tttaggttat ctgatttaac tactttgggg agagttctgg tatgcaaggt agtggataga
571921 gtattcgtag atctacccat aacacaaagt cgcctatgcg aggagatctt ttggcaatgc
571981 caaaaactga gaattcccat aaatacattc cacaaaccag agttttctac cttcaatatg
572041 attcctacgt gggtcgaccc aaaaggaagt ggtttacaaa tctcagttac tacgaatggg
572101 aatggataca tcttggcaaa caggataaaa agagatataa tatcacactt acctccaaac
572161 atatctgagg tggtgataaa catggggtat ttgaaagacc gtattataaa cgaagaccat
572221 aaggccttgt tagaggaaaa gtactaccag actgacatgt cattacctgg atttggctac
572281 ggcttagatg aggacggttg ggagagccat aagtttaata agctaattcg tgaatttgaa
572341 atgaccagta gagaacagag acttaagaga accagatggt tatctcagat aatggagtat
572401 tacccgatga acaagctgag tgacatcaag ttggaagatt tcgagacttc atcttctcca
572461 aataaaaaga caaagcagga aactgtcaca gagggtgtag tacctcctac cgatgaaaat
572521 attgaaaacg gtacaaaaca actacaatta tcggaagtga aaaaagagga gggacctaaa
572581 aaactaggga agatttcttt agtcggaagt ggtccaggct cggtatctat gctaacgata
572641 ggtgcattac aagaaataaa gtctgcagat ataatactgg cagataaact ggtaccgcaa
572701 gccattttag atttaatacc tccaaaaact gaaaccttca tagccaaaaa atttcccggt
572761 aatgcagaac gagcacaaca ggaattacta gctaaaggtt tagaatcgtt ggataatgga
572821 ttgaaagtag tccgtttgaa gcaaggtgat ccgtatattt ttggccgtgg tggcgaggaa
572881 tttaatttct tcaaagatca cggatatatt cctgtggttt taccgggcat aagctcatcc
572941 ctagcttgta ctgtattggc tcagataccc gctactcaac gtgatatagc agaccaagtg
573001 ctcatatgta ctgggactgg gagaaagggc gctctgccta taattcctga atttgttgaa
573061 agcagaacca ccgtctttct aatggcactg catcgcgcca acgttctgat cacgggatta
573121 ttgaagcatg gctgggatgg tgatgtcccc gctgcaattg tcgagagagg atcgtgccct
573181 gaccagcgtg ttactagaac tcttcttaaa tgggtaccag aagtcgtgga ggagattggt
573241 tcaaggcccc ccggtgtctt ggttgtaggc aaggctgtga atgcattggt tgaaaaagat
573301 ctgataaatt ttgacgaatc aagaaaattt gtcattgatg aaggttttag agaatttgag
573361 gttgatgtag atagtctatt taagttatac taatatgtat ataaagacaa gatatcattc
573421 aaacgctgac gttaaagttt taaggttaat cgtgtatgca ttatgttcta gattcatcaa
573481 cactggatat tgagcaaaaa ggacgtatcc gaggcccgaa aaggtccttc aaccaagtcg
573541 tcaaaatatt ggcaagccaa aagagcagcg agaatgattg gcaaacggtt tttccaaaca
573601 acaagtaaaa agattgcttt tgcattcgat attgatggtg tgttgttcag gggcaaaaag
573661 ccaattgctg gtgccagcga cgcattgaag ctgttgaacc gaaataaaat tccatatatt
573721 ttactcacta atggtggagg gttctctgaa agggcacgga cagagtttat ctcgagtaaa
573781 ttggacgttg atgtatcacc cttgcaaatt attcaaagtc atactcctta caagtccctt
573841 gttaacaaat attcaaggat cttggccgtt ggtacacctt ccgtgagagg cgttgcagaa
573901 ggctacggat ttcaagatgt tgttcaccaa acggatattg taagatacaa tagggacatt
573961 gcaccattta gtgggctatc tgatgaacaa gtgatggagt actcaaggga tattccagat
574021 ttaaccacta agaaattcga tgccgtcttg gtatttaacg atcctcatga ttgggctgcc
574081 gatatacaaa tcatctcaga tgcaatcaac agcgaaaatg ggatgttaaa taccttgaga
574141 aacgaaaaga gtggcaaacc ttccatcccc atttactttt cgaaccagga tttactgtgg
574201 gccaatcctt ataaattgaa tagatttgga caaggtgcct tccgcttact agttagaagg
574261 ctttatctcg agttaaatgg tgaacccttg caagattata ctttgggtaa gcctacaaag
574321 ttgacttatg atttcgctca tcatgttctc attgattggg aaaaaagact aagcgggaaa
574381 ataggccaat ctgtgaagca aaaactgcca ctcttaggca cgaaaccttc aacttctcca
574441 ttccatgcgg tttttatggt aggtgataat cctgcaagtg acatcattgg agctcaaaat
574501 tacggttgga acagttgttt ggtgaagaca ggtgtgtata acgaaggtga tgacttaaag
574561 gaatgtaagc ctaccttgat cgtgaatgat gtatttgatg cggttactaa aacgttagaa
574621 aagtacgcat gaaagactac tatggaatat cttttcctgc ctttgagctg tactgttatg
574681 atagatttat taatagctta aacgctttta caaaatatat gcaatataca taacgggtta
574741 aataatgggt tgggaaattg gtaatcacgg tataatgagt acctgttttc ttctatttaa
574801 aaaaataaaa actaccaact ctttttggta aaattagtaa cctaccaaag tcaatcgatc
574861 aatgcatcta aaaaaattca ccttcaccaa agtagaccaa ttgacgtcat ttactgaaac
574921 gaatgtgcag ggtttacaag tcatctgaaa tgctgtccaa attgataggt tgaccaggct
574981 tgaaagcagg aagacccaag tagggacaac cactacatct aaaggcatcc cctagagaac
575041 aagaaccaca gccgccaact ttcttcccat cgatagtgaa atcaatctcg gtcaactcgt
575101 cttctgtaaa tttgacaact ttatcttgtt gagatcttat atcgtttatt tcattttctt
575161 cctgttcttt cataccacag gtgcaatctt tacaagcctt cttcttctta gttttggatt
575221 taccgcatgt aatcatagta atcattgact taccagaacc atcctcgtcg attaattctt
575281 cttcttcaat ggaatcatcg ctggtatcca cttgatcaaa atattgggct ttggaagagt
575341 cactagagaa atcatcatca tcgctatcct caatcaggtc gtctacgact cggtagactt
575401 ttggttcagt ggtcattttg aaactaggtg gtttgaagct gtctgtttcc ttaactatag
575461 gttgcctact gtgatctgct tttttgaatg agggtaaatt agaggttgaa gaactagctt
575521 ttttaaaagt tggtagctta ctaccactct gtagcttagt attgttcgtt ttcttttttt
575581 tcagtggtat agaaacagtt tggtttagtt tagaggaatc cattttaatc cagcaataat
575641 ctggttcgtt aattatttca aacccattga ttaatgcatc tactttataa atatcactta
575701 aaccaattag tgagccgttt ggtttcaatg agtcagctaa gacagaaatt aactttttcg
575761 gaaacttaat atcagtctgg gcttctggcg tcaaatagtg tactgtttca tattttgcgt
575821 tttccaaagt tatggaccca tcatttagtt tattgattaa aaactggtcc acgaacttga
575881 ctttctttga tgcagcttga gccttagtgt tctctactag ctctggcgtt gtagtcaccg
575941 ccggatgtat taaaagtaaa ccagttttgt attgtgacat cgataccttc acttacagtg
576001 tatatgctta gatcaaatgt gatgaaagac ttctgcttag aatacctttt taatatgtca
576061 tgaaattaaa tgattactaa tcatttcttt tttttatttt ttttttccag aagcttttga
576121 atagtatcgg acttattccg gtaccgggat atgtcaaaaa aagaaaaatg agaaacgaat
576181 agatatttac ccagaaagta atgaatgtat ttaatgaatt actgaattat taaaattagt
576241 aataaatagc ggtttatatg aagagctcta tgtacgctag tatggcatta catacctact
576301 gcaagtaaaa aaggaaaaaa atttgtgaca ttttgtaaat atgctgcgtg aatttgccta
576361 atgagtattt ttccagaaat tacaaaacac aaataagtag aatgtgttta gtgtatttgt
576421 aattcataga ctatttattg atgcttatct attatacctg gggtttctgc ttcgtcctcg
576481 tcctcgtcat catcgtcgtc gtcgtcgtcg tcgtcgtcgt cgtcgtcgtc gtcatcgtcg
576541 tcatcgtcat catcatcgtt gttgttttcg ttcttatctt ctgtatcttc ttcttcgtcg
576601 tcgtcttctt cctcatcctc atcatcgtcc tcttcctcgt tattttttgg gtacccaccc
576661 aatttcataa cgattttgtt aacaatctca ttccagtcca tcataccccc gagaccaata
576721 tcaccattta tatccataac tttctcagac ggcttgaaaa cagtgaccca ggacatttcc
576781 tcctttatcg tttgtagttg cttctttgtc atcatagaat taaaagtgct actcaccata
576841 gaaggtgcca aaagaatggg ataactcgga ttccaagctc taatgacact tgtcagaaga
576901 ttgtcgcaca ggcccaaagc aatttttgat aatgtgtttg cagttaatgg agctactacc
576961 agtatatccg cccagcgacg tagttctata tgaagtacag gatcagttcg ttgtttccat
577021 gcgtcccatt catcttggtc ggtccatagt tgaatatgtg ggggtaactc gactacttga
577081 gccatgttgc attgtcctgg tgttggtgtc actggagttg ccggagtgga ttcgtactgc
577141 gacattttat ttagtttttc tgaagatttg ataattttct tggtatatct ttgttcgaaa
577201 aactgtgttg ctgattgagt gaggataact tgaatgctta ttctatcacg tccatatatt
577261 tcttctagtt ttttaatcat tggcttgatc ttaaataccg ataacgaacc tgtagcgcca
577321 aacaacacgt gcaattttcc atcatcttga ggtagtctgg gatccaaatt cttggagttc
577381 tctcttttgg ggatgatgga aggaatgacg gactgcttca ctggcgtttc ttccggggta
577441 gaacgcacat taatttggcc tgaaacattg ttagcttgat cttgtgcatc ttcctttcga
577501 agtgtaatac tggtgggggc tttggcggtt accttattat tttctctact tattggcgtt
577561 gaagtggcca tgattttgtc aggcttcatg gtatcaacta ttttaagagc actgtctttt
577621 ttcttaggat cataatcttt catttcgttg acgagtggag acccagataa ttgcgttgtt
577681 cttgaagtgt tggtgtggtt cggtataact gcatgattgc caggaatgga atttgagaca
577741 ggagcaggat tactatttgg agacttggtc ctttctgagt cgttcttcag ctgagtcaga
577801 ctatcctgct tttgctgttg ctttagatca ctgaaagtga cggcggggac tctcttcaaa
577861 ccaggctccg gagtattact tactactgcg ccggaggtgc cggtggcatt cataatagat
577921 ttcgtagtcg tggtagtagc attcgacaaa gtagggctta ttgattgcct ccctgacacg
577981 ggggagttga ttattgaatc cttccccttc gcatcctcat ggtccaacaa aatctctttc
578041 tgtccacgcg aaaaccttgg acactctata gactggttat ggtcagcatc ttgcttcccg
578101 ctagtagagg cgacggcagt cattgctgtt tgcttctaga tctttcttcc ctattaattt
578161 tttcctaact aatatttctt tatattttat cccggaatat aaagtagtat gacagcaaag
578221 aaggccaggc taaaaaaaga tctctccaaa tgtaactgga cggcgctgat aagtggacaa
578281 gtacaagtga gggatcgtga tccaagagca ctctgtgact tcttctcctc taatatcacc
578341 tccccagaaa agcatcgatg ccattttttg caagagaaaa agttgcgtgc gtcactgccc
578401 acgagcacat ggggtgagtt atataacata agaatattgc tttgactcat gttaaaagca
578461 aaagaaaaaa taataatgat cattagagat acatcaaaga cgatcatggc attaacccag
578521 ggtacgtgtg ttagatatga tagggtaccc cgcgcgtata agttacgcct tgaatgatat
578581 aacacgttaa agtttctaga tcacgtgaat cattaccatt ttttaggtca tcctacggat
578641 aatggcgaaa ccacataatt gctttgtaga tctcttttta tgctggatgg atggccctct
578701 ggaatgcatc cttcacgaac acaatttatg aaacctcagg tttgatgctc cggaaagcct
578761 atttctcacg ttttccggca cttaatgcgc atataaaaac atagtctcta cgttacgagg
578821 atttatcata gaacccaaat cagcagtaat aaatttccac ggtcaaatta aactcttgtc
578881 gttgatatgg gtgtagtgtg atggtggtga ccactatttc gcctttatta gttatttata
578941 tgagttagcc ctccgaagaa ctcatccttg ttagctcagt tggtagagcg ttcggctttt
579001 aagcgcattt gcttaagcaa ggataccgaa atgtcagggg ttcgagcccc ctatgaggag
579061 ttctttactt ttttagattc ggcgttcaat gctaaagaaa aaaaatgaaa ataagtttca
579121 attaatagtg aaagaaaagg aaggaagtta gaactgaaat gcgtagacta cctcccccaa
579181 attttttctt gtttggttgc attatttcat gaattcaact aaaaggctga aaatgtcaac
579241 aacctttcat gattatgact tggaagagcc attaacctca aatgccagac cactaaagaa
579301 ctccgttatt acaatccgag taataaaatc tttcccatat agaaacgtca agaacatagt
579361 gctgcacgat tacgatcttg ctgataaaac tgcaaaggac ctgttcaatg acgttttgaa
579421 caaaattcaa aatgaaggtt cattcagacc attccgtaat gttaagtttg atactttaaa
579481 gatatacacg cacgcacatg gttccaagac ggttaatctc gtgatcaatt ttgaccacga
579541 tgacgactgg actttagaca tagagaatga caaaaaaaag ctgttcgagt atggcattga
579601 gaatgaaacc gaaatttcgc ttttcaacaa agaggattac ctaaggttta aagaaaaccc
579661 tgaagaaaaa tggtgagatg ttgtttggct tatggccttc attaataagt aagtgctatg
579721 aatatattac atatatatat atatatatgt tgtgtacgag agtatactcg tatgtaaatt
579781 aacatcaaat gtgtatgtgg aaatgcagaa gagagcaaac tctcctttaa aaaacaacct
579841 ggttcctata aaaaatgtct tcttccatag tgccaaatgt atagttgctg aactcataat
579901 gagcttcttt tattgtttca tcagaatgag aactattttg atggtgatgg tgatgatggc
579961 gacgatggtg acggcgatgg tggcgggaat gttggatatc gtttatgttg atgagggatt
580021 cgcggatagt cccctttgag tcgatctccc tcttcatcac ggcttggtta aacttcaact
580081 tcctggggaa ttgttccttc ttttcgttca taaggtcttc agaatcttca tctatggagg
580141 aaattttagt gcatgtagaa tgctggtcga aaatggaaga cgtgtgagaa tcaacagacg
580201 atgggcatga aatgtcttct aatttcacca aagcgttgtc attgctctct atagaagcgt
580261 taatctcatc cacctcctcg gttacccagc attccgtatt tttctttaaa gcagatttta
580321 gattttttgt ttgtttctgg tcaatttggt tctggaccgg cgatatttcg ttttcattac
580381 tatctatgtt agtcaaatct ggaccgtaca acaccgttac atcggtttct ttgttccagt
580441 tgatggacag tggattggat ttggagttct gtaaaccata gtgatttatg gaccaacgcc
580501 tccagaggca atgatgtagc ctaacgaggt acatgttgta atctagcacg tcctctgaag
580561 agcaacttgg taatcgaagt agtttatgtt tgcgcatctt caatagtagt gtccatgaag
580621 ccgatatttc caagcttgca tcattaaatt catgatggaa atagtcaatc gcaggcttgt
580681 tgtagttggt catgttatcc agtaacatta tattctggta cgaaattatt gtatcgtcca
580741 aactagtcat tttctgtata tgtatctatt tgtgtgtgta tgaacacttg tgtgtagtat
580801 ctgaatgcga taagagaaag ggccaaagtt gaactgaatg caaaaagtaa aacctataaa
580861 accgtgttga ccatacgctt tcatatatat atatatatat gtttgttttt gctaagaccc
580921 ggtaactgta ctttttctgc agtcatccaa gggaagacaa aagaagaaag aaaaaacaag
580981 attaatgtcc ccaggttttt tcttttcctg gcggaaaaag ctcaaatcta acatttcccc
581041 gcgggggttt ctttgtaaag agtatcgagt cggaaacgaa aaaaaaaaaa agatgagaaa
581101 atgaattttt ccggtcgcct aaagatagag gtaccagcgg aaaaaatgca gcaaaagcaa
581161 aataccccat tcaagttccc cctgtctcgc ccctctcacg cttcactgtc ccccgctttc
581221 ggtttttccg gctacggcat ttctgttgaa agttgccgga aaaaccccaa aaagcataaa
581281 aaaaaagagc ggggggaaga aaaaaagatt cctttctatc ttttccttcc ccggcctatt
581341 cgggtactcg cttccgggtc cgctgtcgtt tataatgatt agtgcagaga gctttcttct
581401 cttagttttt catgtggtaa aggcaatgcc atttagaagg atactacgtg gggttcaaaa
581461 ccgtgaatac gttgtctatc gtgttatgta tgttctgagt ttctttttgt cattctacta
581521 gtttatggac tgggactatg tatcttgcag tatgatttcg tcaggaagct tgtcatagca
581581 aggcctgaac aaatcgtacg ttaaaataaa aatgagcacc aattcgagtc actgatgcct
581641 actgctcaat ccaaccatct agttctgcaa agatacttac tccgcataat taaaaaaata
581701 aggtatttta aagttgtgta gtgacgaatg tagtgacgcg gaaacgtttt actcgtcaat
581761 ggacatttgc gaatgtgtcc gataaatagt tgaggctttt cctgcattct gtcaagaagg
581821 gtatgtgtat gaacatgcaa atgacactgt aaaatgattc attaccctga ttatggagtg
581881 attttctttc cttttttttt ttacatttag tttcattatt atgcaaatta gagggtatac
581941 agttgagatt ttaacacttt gaattaaaaa gtgttacaga ggaaaccgac gcaaaaggct
582001 tggtgacgca aacttttcca tctttatttc acctcttcag acggtcctaa gaccttttga
582061 acgtatcaat atagttttat catctgttct ctgttgttct ccgttactaa gatattagtc
582121 agctcttgaa atttcacacc cctatttatt tgtcttagcg tccaacccct ctcaaccctt
582181 ttccatttct tgtataaagg tagttaatta ggtaacgctg ctcttaccat cactacagtg
582241 cttacgagaa tttacccaaa ccctgcgcaa gataaataag aaatgtcgaa acagtgggcg
582301 agtggtacaa acggagcttt caaaagacag gtttcgtcct tcagagaaac aatctctaag
582361 caacacccaa tttataagcc agcaaaggga agatattggt tgtatgtttc acttgcatgc
582421 ccatgggccc atagaacact aattacgagg gctttgaagg gattaacctc tgttatagga
582481 tgtagcgtag tccattggca ccttgacgag aaaggatgga gatttttgga catggaaaag
582541 caattggagg acagtgaaga ttttttggaa cattggcacg atgttgcagg tggtattaga
582601 actgctaaag aggattccag caagagcttc gccgagatca agaatgacag tcaaagattc
582661 atggttgatg ctaccaatga gcctcactat ggatacaaga gaatcagtga cttatattac
582721 aagagcgatc ctcaatactc ggcaaggttc accgtcccag tcctgtggga cttagaaacc
582781 caaacaattg ttaacaacga aagtagcgaa attataagga ttttgaactc tagtgcgttc
582841 gatgaatttg tcgacgacga tcacaagaaa acggaccttg ttcctgctca gttgaaaaca
582901 cagatcgatg acttcaattc ttgggtttac gacagcatca acaatggtgt atacaagacc
582961 ggattcgcag agaaagcaga agtttacgaa agtgaagtca acaacgtatt tgaacatttg
583021 gacaaagtgg agaaaatcct gagtgacaaa tattccaaat tgaaggccaa atacggtgaa
583081 gaagatagac aaaaaatctt gggtgagttc ttcactgtgg gtgatcaatt aacagaagct
583141 gacattagat tgtatactac cgtcataaga ttcgatcctg tgtacgtcca acatttcaaa
583201 tgcaatttta cctctattag agccggatat ccatttattc atttgtgggt aagaaattta
583261 tactggaatt atgatgcctt caggtacaca acagattttg accatatcaa gttacactac
583321 acgcgttccc acacaaggat caaccccttg ggaattacgc ccctgggacc caagccagat
583381 attcgtcctt tataacaagc tgtaattaaa taatcaaatg tctataatct ccctgagttg
583441 cctctttttc tatactcaat tgggtaattg acgcgaaacg cgttaaagtg caaaaaaagg
583501 cctggaaatt atatttaacg caatgaaata ttttcataat atgacattca tgcacagctg
583561 tattcattct tctactttgt agtttgttat tcttctttat cggtttcgtt ttacaaaaga
583621 ttttagcaag gaagcagttt ttaaaccaat caatggtata cacaacaccg caacaacagc
583681 agagattcag ctccacaccg caatctagcc acactcttat cttctcgcca atcagagccc
583741 cttcaatgca aacgccctcc tcattggatt accaatcacc ttcaattgtt gtgtcatcgt
583801 cttcaatgaa ggttcacggc cggtcttcca gtttcggtaa attttcactg tctattgggc
583861 aaaatggtaa ggctacaata ctggggccta taaacgtcct tcccactgat acatcgaaaa
583921 tggagaaacc tgtaccaaag aaaaagcctg ttacttctga ccgtgtcgaa aagactcgta
583981 tattatcttt gttgaaaaaa atgagaaaca agagcagtac tgtcaacaaa aaatatagta
584041 aagtaccatt aaagtctacg acaagtttgc aaccagcagc tactgcacct tcaccactag
584101 tgtccaacat cataaagccg tctcccaaaa agttagcttc cccaagaact ccgaatgcaa
584161 actccaattt aaatctaaac tttacttcat ttcagattaa aacaggtttc actcccaatc
584221 tcgatggaat tttacttgaa aacttcacgt ctcctaacac aaccgctgat tcacagggta
584281 attccgccag taacatcata aataataatc acggtagcgc aaataatacc aaccaatttc
584341 tttttaatct accacttcaa tcatcaccaa ggcaattcag gtctcctgca agattaatag
584401 atccccttcc catatcggac tggaacacca gtctcttgat gtcaccccca agaacgacga
584461 attttgaatc tgcaaacaat cacttcaatt caaattttgc tcaagcatcg atgttaagac
584521 gcccttcact accgcacata gatgaggtga ttccacagga ctctaatcca gccaattact
584581 cagatagatc ggactatcta tctgtggacc agaacgccaa taatcataat ggtgcacttt
584641 cagaacagac ctataataat ataatgaaat cttctatgat ttcgttacct atagaaaaag
584701 atgatgccac aatggcacta cgaaaacttg tctccagaga gtaggtccat ttggttttcg
584761 taaaatacac tacgtaagat ttcattatat attcaaaacc gaagaacttt atttaattaa
584821 ttctattcaa tatttttttt ttcccattaa attgtgtagt ggaagcaaaa tgcactgcgc
584881 ttatgtgaaa aagttacaca atagggaata catggaacag cagatcagaa ctgcaaccct
584941 acagattaga tatggagaac gacaaggcgt cacatgcgag cccaagcatt ggagtgaacg
585001 aatttgtcgt tcaaggggag atatccatag acgactccga aaggtctgtc aagagtgtta
585061 gcgttagcat aagtgatgat gaggatagta agacagatgt acaagataat atggccacac
585121 cgtccacaag atcgaaattt caaacagatc tggccattga taataggcta ttggaaaaag
585181 atccaaagta caaaaaactt ttcactgaaa aaagaagacg tcgaagacca gaaagctgta
585241 ttaacctcat gactaaaggt aagggcactg gacaaaaaga taacattaat gatcaaattt
585301 tcagcctaag aatattacca ggctccgatt taaactcttt aaaggattct ttatggataa
585361 taaagatctc tacccagcca gatgttgaaa aaacaatcgc aagagctttt tctgatttct
585421 attggttata tcatcaatta caaaataacc actggggaaa aacgattcct ccgcctacaa
585481 ggtccaacat tcttgtagag aaggacgaat ttgccataaa tcatcttttt atgatacgta
585541 ataatgagaa gtatgatcca atttttaatt tcaaaccgga atatatcata tcattgcaat
585601 tgatggcaat gattaagcac atattcaatg acaaggtttt acgtttggat tcaaatttca
585661 tagattttat tagttgggat gacgatcttc ctgaaagttt gcaaatagta gtcgatgaca
585721 gtaccttcac aggggataaa atactaatga catcttctca atttcgagaa ttaaaagagt
585781 ttcataaaca atcaaaaaaa gtggaatcaa taacaaattc acatgcttcg ttaatacccg
585841 taacagaact taccgaaata tatataagcc cgaccaaatt attctctaga aaagactacc
585901 aaaggctttt tcaacctcaa agcacagaca acacctttaa taacaatgac ccgttgattc
585961 aagagtggat accaaaaagc aaaacattat tcactagttt atcctttggt tcaagtgcac
586021 ctacttatca agaagcgtca actgagatac aggcatgcca tgactgggta agcatatcca
586081 aggagcaatg gaaacagtta ctctaccatg tattacagta cattgtagac gaggcagtga
586141 aggtgaattc tgtgataaac gaatttactg agtgtcttaa gcaaatttct ttggacgaag
586201 tcattagagc aaactctgaa ctatttttga aattttccaa actgaatgaa tcctttctaa
586261 aaaaattcaa aggtgcatcg aggcaagaca ttctgaagct aatcatatta tttgatgaaa
586321 atgtaagatt ttgcgaatca tttgaatcca tcttaaatca aagattgaag cttggtaaaa
586381 ttctaagcat catagaagtg gatctagaca agaagaaaaa ctttcttgac aaactatctc
586441 cgggaaacaa caacagtaac aatgaagacc ttaagatacg cacggcagag gatgaatacc
586501 gcattgtatt aaaaagatat aaccgtgtta agcagagctg ggagaaaatt atggaagata
586561 tcttaaatga acggaaagaa tttgagaaga gagaagccgc cgaggttaat agttgtttaa
586621 aatcaataag agatttgaac atggatgaaa agaaacacta tttacaatta tggcaagact
586681 ttgtaccaga tgagcacata agccaatgaa tatgtacata ataacgtaat taaagaagat
586741 aatttactac tgaaaaagca acaatataag aagttaagat gaattatact aatttttctt
586801 gtgtttctta agtttgactt ccaaatcttg tacgctttca acgtcatcaa catcttcttc
586861 ttcttccttt tcttcaacaa atgccttatt cagcagtgga aaaatacgct gctgttcacc
586921 aattttctca taatcaacga tcatactgtc gaaagcaaaa caaaattctc tcgccatcac
586981 atcaatatta ttgtctaatt ggggcaattt gggatatctc tgggaaaagt gtgttaagat
587041 caacttccta gcattcattt tgttcgaaac accgattgct tcattaatag tgcagtgttt
587101 tttcttcacg gcatcctcca gtagctgatt ttctagtgta gcttcgtgaa ttaatagatc
587161 tgaattatag cctatttcga gggaaaattt ctcgatgtta ggtcttgtat cgcctgaata
587221 tgaaaccttg aatgtattat gctcattgtt ttcgtccatt cggaaggtaa ttgagttcga
587281 atatgcccag tcacaatgta tagctctgca agtttgaaaa tattctatcg ataaatcctc
587341 atacatttgt ctgatcaagt caacatccct atatgaagaa tctctatcca gttccagttt
587401 tctgtttgat tcttgattgc tattttcttt caatatttca ttgaactctg ccaaaggaac
587461 agattgtgtc tgcattctta caaacgaatc attgatgaaa tgctcacaac ttatgtattt
587521 gattctcttt aaaatctctt tattttctag aactaaccat tcattaacaa atttgtgata
587581 ttgccatgga gtaaccacat atatataact cgtttcatca tccttgttat atttgtacca
587641 ttcatttagc acgctgatta ttcccaaatg gtggtctgca tgcaagtgac tcagatatat
587701 cattttcaaa tcctgaaata ttgacttgac tgctagctga gaaaacatcc tgtgtatggt
587761 acctaaagta ttttcaccag catctagcat aatgtttcta tttatggtat ttccatcggc
587821 gtcagtaaaa ggaactttaa caagtgtgga gacaacgttt ctatatttag aaggcaatgc
587881 actaccggtt cctaaggtga taatttcaac gtgtttcttc ttttctgctg aattgttaaa
587941 gttatccacg tgtagttgat tattgataac tgtatcgaca tcagctaagg gaaattctaa
588001 tggttttaca tgttcttcga aaatttcttg ccacgagaaa tccgccactt caccgttgat
588061 gttgcatttc atcggttctt cgttcatccg aaatggttcg aaagttactg tcttgttttg
588121 tgaaaaaata tgaatgttat ccttctctat tattgtattc aaaggctctt cctgggattt
588181 acacatagat gtacctctgc tgagtggtgt atcgaatctg tcgtagaagt ccttggaaaa
588241 cacacgatct gtttttggta aattgtaatt atttacttgt agtgccttta atttcaatgt
588301 ggtcaatgca gaaccgaaaa atgatatcgt gtttggagaa attttattgt gggatatcat
588361 atgatttact ttaccataat tgtttttctc aaatatgtca atgaacgcga atagattatc
588421 attaatggta acctcatcac caagaaaata atacaccatg ccaagctcag cacaatcata
588481 atccttgaat ttttctacga aagcgttcaa atataggtca tctgggatat ccaggatcaa
588541 tactttggca aaatgacgtt cattctccaa tacctgttcc ggagttacaa caataccgtt
588601 atccaaagta attgtttggc ccttggttaa ctttgcaaat aagggaccct tcggaacacc
588661 tagtttaata gcttcctcca ctttaaattt acccctcact ggactgaatg aaatctcgta
588721 attcgtagaa acttccactt tggcgtctaa gtcaggcaac tctacattca agtgcggatc
588781 actagaagga tcgtacctat cggtgggtgc atgtttgggg aacatttttg ctactatgga
588841 acgtaataca cctttttgaa aactatcgaa gacgcctaac ctgtcttccc ccccattttt
588901 cagaacatta aaggatttaa cagctattat cttatcttta tatacttcct tgtctttcat
588961 aatgtgatcg ttcaagtcta ttccgaatct aaagacgaag tatctccaag tggaaactat
589021 gtaattcaaa atgtcattgc cgtaatgcaa aacaagatta cttttccctt gatcagcaat
589081 agtcaaaatc attccaggta atccacctat atctgaccag tttaattcac cagtaaggaa
589141 aatatccttc aatttggata tcctgatctt attttcagtc agactccttt gggatccttc
589201 accaatttta ccgaagaaat acttttcccc atgtgcagac tggactagca gcaatgggtg
589261 ctttgtatcc gatgtaggat gggtgatggg tataaatgtg aacatcgttg aaaaccttcc
589321 aggactcttt tctttgcggg tggtcgttct attagtctgt tgctttttag gtccctttct
589381 gtatgattta tacctcctga ccaaatggga aaatgcagat gagaaggatt tcaagtgtga
589441 atgactattt agtagtatat tcgacagttt gaattatgct tgaggaagat tatttcactg
589501 ccgctctata tcctttcggg tattttagag agagaaaagg aggcaaaaaa caaccaccta
589561 gacagaatca ttaaaaggtg gtatgaactg ccgaaaaagg gcccaagaca aggtttagga
589621 tgctaattat gtcttccctt tacgtcagtt atagattatg cgatgcccaa aaattttttt
589681 cactgcgggt aagtgttctg aaataccgag cagttactat gtagaaacgc tacgtcctcg
589741 tttgagatat cagtgggcga tattaatgca accaggaata ccgcaacccc attacaatgg
589801 cctagcaaac attctgtaac agcaattttg atttgttgag tgggttgctc ttttttttat
589861 agcatgacaa tgatatccgt aggaacagtg acatcgtatt tcaaatatgc attcgaaaaa
589921 aaataaccca actgaggctg tagtatattg tttatgcagg ctgtcacctc cataaattga
589981 tattttatgg cattattcgc tactccaagg taccctaaga ggccctactt ttttgcgaaa
590041 aaccccaaga caatttattc ttttcctagt ccaagtcctg acaaaaaatg aaagccctgc
590101 gactcttttt ggcggagtca gcccgaatca acacaagccc taatattccc aatgaactgg
590161 taaatagatt tctacaacgt tgtaaagact aatattactg tctttactat tatgatatat
590221 tgactcagta gaaaaggaaa aaaagcaact acgcaaagta tttaagtgcc ttgcaaccag
590281 cttcttcttg ggctgagata caatacctcc ttgtctattc aagtgtacag tatcgcaaag
590341 cacagtaaaa ttaattccta tcaacacaac ccatcaatat aaatctatag agaaatgtcg
590401 aagcctggtc gtactatttt agcaagcaag gtcgccgaaa ctttcaatac cgaaataatt
590461 aacaacgtag aggaatacaa gaagacacat aatggtcaag gtccccttct tgtgggattc
590521 ctagctaata atgatcctgc tgcaaagatg tatgctacat ggactcaaaa gactagcgag
590581 tcaatggggt tccgctatga cttaagggtc attgaagata aggatttttt ggaagaagcg
590641 ataatacaag ctaacggcga tgactctgtg aacggtatca tggtatactt tcctgttttc
590701 ggtaatgctc aagatcagta tttgcaacag gttgtgtgca aggaaaaaga tgtagaaggg
590761 ttaaatcatg tttactacca aaacctgtac cataatgtca gatacctgga caaagaaaac
590821 cgtttgaaat ccattctacc ttgcacacca ctagctatcg ttaagatatt ggaattcttg
590881 aaaatttaca acaatttgtt accagaagga aacagactgt atgggaagaa atgcatagta
590941 attaacaggt cagaaatcgt cggtagacca ctggcggcgc tattagccaa tgacggtgcc
591001 acagtatact ctgtggacgt taacaacatt caaaaattca cccgtggtga aagtttgaaa
591061 ttaaacaagc atcatgtgga agaccttggg gagtactctg aagatctgtt gaaaaagtgt
591121 tctcttgatt cagatgtggt catcactggt gtccctagtg aaaattacaa attccccacc
591181 gaatacatca aagaaggtgc cgtctgcatc aattttgcat gcaccaaaaa ttttagcgat
591241 gatgtcaagg aaaaagcttc tctttacgtt ccaatgactg gtaaagttac cattgcaatg
591301 ttgttgagaa acatgttacg tttagtaagg aacgtagaac tgtctaaaga aaaatagaac
591361 atttgtggct gttcaaataa gcataggtaa aacagaatac ataaaaataa gggaaaaaaa
591421 gaaagatcat ttgtaatgta cttactacat acatatagaa ttctcctctc ttagattatc
591481 atataatata caaagtttat gggtcttatt tcttctgtct tttagcagag ggctcaatat
591541 cagtggcact gacgaactct tcttcgtatt cttgtccatc atccgaatac gacgcttcat
591601 cttcgtagtc ttcatctacc tctccatcac cttcttcagt tccttggtcg aatttggatt
591661 tcaaaccctt catctttctt gtttgtagtt tacccaaatc ttgtttgccc atatggattc
591721 tacccaattt atcacccatg atatctaatt ctacattctt ctttgtcttc atttctaatt
591781 gttttggctt cttgtgagct tcagtgacca tatctggact tggagtatga attctgccga
591841 ttttgaaatc tagacgtggc ccaatctcca ccaattcaat acgtggtaat ctcttaccac
591901 cttggtcgct tttataactt tttaatttgt aaacacggaa tagaacgttc ggcaatggct
591961 caccatcttg gaagtcacct tgaatggtca tggaaatgac atgttgtaat cccgcaacat
592021 cctgtaaatc agtagattcg cctctaaaga aatctaaaaa caaagattta atttgcttgt
592081 atacgggatg tgtatcaaat gcagcacctt ggaatgtaaa cataggcttc aaccctacag
592141 taaatgttaa tttcttaaaa tcagataaca acttgaaatt atctgcaacc attagttcaa
592201 tcatatcata tattttgtag ccaaatgtac gtataaaggt catgttgttt ttacgctttt
592261 tggaacttgt catcagcacc atcaatgaac agtcattctt ttcactaaag aactctagtg
592321 gcgacatgtc ttcgaaagga tgaatatcat tcttacgatt gaacctcttc atatctggct
592381 tcttcaaggc actcaaatct accataatat cgtgcagatt cttgttacag ctttgccctg
592441 gaatgaatag cgcttgcttg acattctcta ccaacttagc ttccctcttt accaaagctc
592501 tcttggctct tgcattcttg ggttttacgg ttctaatcat tttttctgcc agtgttctcc
592561 tgcgcttttg gatatgataa cttcaataca actcatcgat ataccaaatc actttccaat
592621 aatgcattac actataagaa aattcgatcc ttagctcatc gcaaaaaaat gaaaaatttt
592681 caaatcgtat aaaacgatat atttgaggat ttaggaatca aaatagcaga ataaaccaaa
592741 acatacacca tttaggaata aggtttagag gagctcgagc atactgttac atccaattca
592801 agtgaagtac attaggatag ccatatgagt gaaaaaaaag tacatcttcg tttgcggaag
592861 gaacttagcg tacccattgc ggtggttgaa aacgaatccc tggcgcagtt gtcttatgaa
592921 gaggaaagcc aggcctctct aatggacatt tccatggagc agcaacagtt aaggttacat
592981 tcgcactttg ataattccaa ggttttcaca gaaaataaca gatacatagt aaaaaccctt
593041 caaacagact acagtagcgg attcagtaac gatgacgaat tgaatggata tatcgatatg
593101 caaattggat atggactagt caatgaccac aagaaggttt acatctggaa tattcactcc
593161 actcaaaagg atacgcccta tataactgta ccatttcgtt ctgatgataa tgatgaaata
593221 gcagtcgcgc ccaggtgcat actaactttc cctgctacaa tggatgagtc tccattagca
593281 ctgaatccta atgatcagga cgaaaccgga gggcttatca ttatcaaagg tagcaaagcg
593341 atatattatg aggatatcaa ctccataaat aatttgaact ttaagttatc tgaaaaattc
593401 tctcacgagt tagaattacc catcaactct tcgggcggag agaagtgtga cctaatgtta
593461 aactgcgaac ctgctggtat agtgctttct acaaatatgg gcagaatatt ttttataacc
593521 attagaaatt ccatgggtaa acctcaactg aagttaggca aactattaaa taaacctttc
593581 aaattgggta tctggtccaa aattttcaat acaaacagtt cagttgtctc attacgaaat
593641 ggacctatcc tcggtaaggg gacaaggtta gtatatatta ctactaacaa aggaattttt
593701 caaacatggc agttgtctgc cacgaattcc catccaacaa aattgattga tgtaaacatt
593761 tacgaagcca ttttagagtc gctccaggat ttgtatccat ttgctcatgg tacgttgaag
593821 atttgggact ctcatccatt acaagatgaa agttcacaac ttttcctgtc atctatttac
593881 gacagttcat gcaatgaaac atattatatt ctttccacga ttatcttcga ttcttcttct
593941 aatagtttta ctattttttc cacttataga ttgaacactt ttatggagtc aataaccgac
594001 acaaagttta agcctaagat atttatacct cagatggaga atgctaacga taccaatgag
594061 gtaacttcca ttttggtaat gttccccaat gctgttgtca ttactcaggt gaactcaaaa
594121 ttggactcta gctattcaat gagaagaaag tgggaagata ttgttagcct tagaaatgac
594181 attgatataa ttggttctgg ttacgactca aaatctttgt atgttttaac gaaacaaatg
594241 ggggtgctac agttttttgt gaaagagaat gaggaaacaa attctaaacc ggaagttggg
594301 tttgtcaaat ctcatgttga tcaagctgtt tatttctcca aaataaatgc aaatcccata
594361 gatttcaatt tacctccaga aatttcacta gatcaagaat ctatagagca tgatttaaaa
594421 ttaaccagcg aggagatttt tcattccaac ggcaagtaca taccccctat gctaaatacg
594481 ttggggcaac atctctctgt ccgtaaagaa ttttttcaaa atttcctgac atttgttgct
594541 aagaacttca actataaaat atcacccgaa ctgaaattgg atctgatcga aaaatttgag
594601 atcttgaatt gctgtattaa gttcaatagt atcatcagac aatctgatgt attgaacgat
594661 atatgggaga agactttatc aaactataat ctgacacaaa atgaacactt aactactaaa
594721 acagttgtaa tcaacagtcc cgacgtattt ccagtaatct ttaaacaatt tttaaaccat
594781 gttgtgtttg ttttgttccc atcacaaaat caaaatttca aactaaatgt taccaattta
594841 atcaacttat gcttttatga tggaattctt gaagaaggtg aaaaaactat aaggtatgaa
594901 cttttggagt tagacccgat ggaggttgat acatccaagc taccatggtt cataaacttt
594961 gattacttaa actgtatcaa tcaatgtttt tttgatttta catttgcgtg tgaggaggaa
595021 ggaagtctgg attcttataa agagggcttg ttaaagattg tgaaaatttt atattatcag
595081 ttcaaccaat ttaaaatatg gatcaacacg caacccgtta aatctgtgaa cgccaatgat
595141 aattttataa atatcaacaa tctttatgat gataaccacc tggattggaa ccacgtcctt
595201 tgtaaggtaa atctaaaaga acagtgtatt caaatagcag aattttacaa agatttatct
595261 ggattggtgc aaacattaca aactttagat caaaatgact caacaaccgt atcgctatac
595321 gaaacattct tcaacgaatt ccctaaagag tttagcttta cattatttga atatttaatc
595381 aagcataaaa aattgaacga cctcatcttc aggttcccac aacaacacga tgttttaata
595441 cagtttttcc aagagtccgc tccaaagtac ggtcatgtag catggatcca acagattctg
595501 gatgggtcgt acgcagatgc catgaatact ttaaaaaaca ttactgttga tgattcaaag
595561 aagggcgaaa gcttgagcga atgtgaattg cacttgaatg ttgcaaaatt aagctcgttg
595621 ctagttgaaa aggataattt ggacattaat actttgagaa agatccaata taatttagat
595681 acaattgatg ctgagaaaaa tatttcaaac aaattgaaaa agggcgaagt tcagatatgt
595741 aaacgcttca agaatggctc tatcagggaa gttttcaaca tattagtgga agagcttaaa
595801 tcaacaacag tagtcaatct atcggatctc gttgagttgt attctatgct cgacgatgaa
595861 gagagcttat tcataccgct aaggcttctt tctgttgatg gaaacttact gaattttgaa
595921 gttaaaaagt tcttgaatgc tttggtatgg agaagaatcg ttctactaaa tgctagtaat
595981 gaaggagata aactgcttca gcatatagtc aaacgtgttt ttgatgaaga actacccaaa
596041 aataatgatt tccccttgcc cagtgtggat cttttatgtg acaaatcgtt actgacgcca
596101 gaatacataa gcgaaacata tggcaggttt cctattgatc agaatgccat acgtgaagag
596161 atatatgaag aaatatctca agtggaaacg ttgaactcag acaactcact cgagataaag
596221 ttgcactcga ctattggttc tgtagcgaaa gaaaaaaact ataccatcaa ctatgaaacc
596281 aacactgtag aatactaata tctataatac aattttacat atatataata aactttactg
596341 gggaatgata ataataaata tgtatatgct attatcgcaa ctgccttctt ccgatttata
596401 taagatcctt ttctttctgt tcattcgtta ccatctaccc taattctgac cattgtttcc
596461 ggcaagggta ccagatcttc atcctcatca ttatcttcat cattcttatc attttcttgc
596521 gcttcaagac ctgtttcatt tgattgttca gattcctttt tcttagaatc tttccacggt
596581 cctatctcat aatcaccctc tgcatattgc aataatccca aacttgcttg cgatatattg
596641 tttattatag aatcccaatt gttcatcaat tgggccactg aatccgcatt cattcccatt
596701 tctttgatct gctcattcaa ctctgttagc tgaattttta agccatccgt taaactggtt
596761 atcttttgta atgactgaag ttcttttcgc tttatagcaa tttgttcatc tattgaatcc
596821 ataataactg tctgaattat gagtttttca aacctattca atagtttttt agatatattc
596881 agaggcaggt attcttttgt attgtcgccc tctaaccttt tgtaagtact ttcatatttt
596941 tattttcgcg ttacactaaa ttcaaatatt aaaaaaggat cgctattaat gtgtagaaat
597001 tgaaaaaatt acatacagaa gcgtataaaa ttcttatcat ctattttcac ccttctactg
597061 agttatttcg gatattttac ctgccgcaat ggttctaccg tcctttctaa gaacaactct
597121 tcccaaacgg tcattttcat gggcagttaa taaaggaatc cacctcttta cttcaattag
597181 ttctatttct acaaatgctc gttgtttaga gcctagatgt ctaatctttt tcttgcttgc
597241 agtattgccc ttgtctataa atgaaatcaa tcttttgatt cgagcaggtt gctccttgac
597301 tccgatgaaa agaataaacg gtgttcctgg cagcaaaggt cggttcatgt caaaggtggt
597361 caattccaga acaaaacact gtgctgaatg aatggacgaa taatcaactg atgctgccaa
597421 atcaccattt tgaatatctt ctggataggc tttgcgcaat ttcaaagtga caaaatcacc
597481 cttaatggca acatctgtct cttcgtgatt cgttgattgg ccctgttgag aaccaacctg
597541 aattttatcc acaatacaac tctgttccga cggatatatt gtcaaagatt caccaggttg
597601 aatagaacct gattccaatt ttcctgaaac tagtgctaaa tcgttacttg tttttttcga
597661 tgggatgatc tccaacacag aaaacaaaaa cggatcatct ttgttaattc cttcattctc
597721 ctttgaaatc ttgaacgccg cattttccaa agtagacatt aagttaggac cattgtacca
597781 ttgtctcact tcatctgtat attcaatttt ataaacacct tctccggaaa agccactgat
597841 aggtacccaa ttaatattat cctcaaaaaa cccaatatca accagatatg gcaacaattt
597901 cgatttaatc tcttcaaacc tttgttggga ccagtcaaca ttatccatct tattcatagc
597961 aataatcaga ttgtgaattc caagactaga tgccagtagc atatgctcct ttgtttgccc
598021 atccaagtca aatcctgatt cgaaagcatt ggtgctacag tctacacaaa gtatagccat
598081 atctgcttgt gatatcccca ttatagcgtt tggaacaaaa tctctatggc ctggcgcatc
598141 cacaatagta aaatttgccc tatgggtaga gaaatgcgat gtacaaattg acactgttac
598201 accacgttcg cgctcttcat ttgtctgatc cataatccat gcaaatttga aggatgactt
598261 acccatagtt tcactctctc tttgtagctt tctcagttgg gattggttga caatgttcag
598321 atcataaagt agtctgccca ttagagttga ttttcccgca tcaacatgac caagaacaac
598381 aaaacttaag tgaggtaagg cagatttaac aaatgcagaa atatcatgag gtttctttgg
598441 tttcgttggc accgtagtct tatagtatct ttgaactgtc ttttcatcat tggcttcctc
598501 accattgcgt tcaccctcac tttcttcctc gtcaagccag tctggaagcc gatcatttgg
598561 cctttgttgc gaaattgaga tgtttgccag tttttgagta acattcgcac tcccattagc
598621 agcagcaatt ggcttctttg gtgtcttctt cttcttcaaa gttttcttca attccgccag
598681 cgtgctttcc aaatcgaaat tgttgtcaaa caaagctagc ttaagtgaaa gattatccca
598741 gccttggtaa tcctgtaact gcgcctttag agtaggaaat acctcgttca ttagatcata
598801 ttcatcgtca ttcaaataat catcaaattc accttcgtcg tgaaagtccg gcatgtcgtc
598861 tgctccatcg ctgtagtcac tgtaagccat ctcgatagtc aatagttgtc gaagcagaag
598921 cctttgggtg tctccaagct gtacttaact ctttttaaat tgcttattgg ttagctttca
598981 tgtggtatat tcaagtcaca ttaatgggcg tctccgtgca ttgtgatcaa tatatgaata
599041 cgaagtactt atagagtagt atttacacga ttgttattat atttatatag cattcacgcc
599101 tggtaccaca ggagttttct acgcttacgg tcctctctgg ctatacgcct cttctccttc
599161 cagcgtgatt ggatttcttg caatctactt tccataattt gtacatgttg ttcactaggt
599221 ttcgagacca tggatacaaa taatggcgaa atgccatatt ttgcagccaa aaatttgcgt
599281 gtatactttt gaggattgtc aagacgtaac ttccggatct catcaatttc ttgaggtccc
599341 agatgatagg ttttgccgtt cactgtgctc ttacctacga gaacatttgg acactgcttc
599401 gctttagtgc tttgaacagg catgtcaagc cctctacgag ggtcactggc tgccataaag
599461 ctacgtggaa tggtctcact gttaacagat ccggttgcga tggattctga tggttgatag
599521 tacattcctg gagcatctct gtgctttaaa taccctttat agttagatgc gctcttagtc
599581 ttgttgtaaa tcgttgtcac ttgtgttttg ggaaatccaa attgcttcca ggcagatcca
599641 gcagtgtgga acgatctgca gcacacacct ctgccaatca ttcttgtgct attttacttt
599701 gtctttaatt ttccatttta acttgttgaa agtatctctt tttgccctct tttctatttt
599761 ctcaaataat aaaagcggtg aaagctgaaa aattcatgag atgactgcag atgataaaac
599821 acaagaaggc ccaaagacaa tacaaatacc tctggtatgg gtcattcggg gcgtgaggaa
599881 aggataaaag acatatttaa ggaacttacg tcaaaagaac taacgcctgg gttgcttttg
599941 acactgcaga aactagcgca aaagccgaat actaatctag aacagtttat tgccagctgt
600001 aaagctttga cgaaactcag cagtaacaat ccaatcattt ttaatgaact tctggagctc
600061 ctcaagaata aatctgaaga ggactcgaca ggcccaaaga aaatcgcccc ttctataaat
600121 aagagaaaga aatttaagat ccagttagac cttgacgata atgaagatga gctagattct
600181 ccagttcaaa aaaaaccagc acctacacgg acgttgttca agagaataga taaactaaag
600241 gccaaacagt tgaggcagta ttcgcccacc gtgaaggatc cttctccaaa tagtgaacag
600301 caaacacaga atggtcatgc tgaaacgaag gactatgaac cgactcgaag cgaagtagtt
600361 gaggaggaca gagaatggta tgataatgat gatgattatg gaaatttggt gcctgaacct
600421 ctgtctgaat tgcctgagga agcgaaacta ctacctgtca ttaggaatat cgacaacgat
600481 gatgccttac gaaataccgt tcaattatac cccataccac tcaagcaaag aatggaatgg
600541 atccctcctt ttttatcaaa gtttgctctt gaaaacaaag tgcccacttc cataattatc
600601 gggtccatct ctgagacgtc cagccaagta tccgctttat caatggtgaa tccatttagg
600661 aatcctgaca gtgaattttc tgcgaacgcc aaacgaggta gtaagctggt tgccttgaga
600721 aggataaaca tggaacatat tcaacaatct cgagacaaca ccactgtttt gaacactgcc
600781 atgggggaag tactaggctt ggagaataac aataaagcaa aagataagag caaccaaaag
600841 atttgcgacg atacagctct tttcacgcca tcaaaagatg acattaaaca tactaaagag
600901 caactgcctg ttttccgctg cagatctcaa ttgttatcat tgataagaga aaatcaagta
600961 gtggtgataa ttggtgaaac gggctcaggt aaaaccacgc aacttgcaca gtatttatat
601021 gaagaaggat atgccaacga tagggggaaa tctattgttg tcacacagcc gagaagagta
601081 gcagccatat ccgttgcaaa aagggttgca atggaaatgc aagttccatt gggtaaggaa
601141 gtaggctatt ctataaggtt tgaagatgtg acggattctg agtgtacaaa acttaagttt
601201 gtaacggatg gtattctact cagagagacc ttattggatg atacactcga taaatattcg
601261 tgtgttatta ttgatgaagc tcatgaaagg tcattaaata cagacatttt actaggtttt
601321 ttcaagattt tattagcacg tagaagagat ctaaaactca taatcacttc agcaacaatg
601381 aatgcgaaga agttctccgc attttttggt aatgctcctc agttcacaat tcctggaaga
601441 actttccccg tacagaccat atatacttcc aaccctgttc aagactacgt agaagctgca
601501 gtttctcagg ctgtgaaaat tcatttagca aacgattgtt caagcggtga tattctcatt
601561 ttcatgacag gtcaagaaga tattgaaaca acgttcgaca ctctgcaaga aaagtttttg
601621 caagtatatt ctaaaaagtt tggtaccgca aactttgaag agatcaatga tattgaaatt
601681 ttaccaatct actcggcttt acctgcagat ttgcaattca aaatttttca ggatctacat
601741 ggcactaaaa ggaaaattat aattgcgaca aatattgcag agacttcatt gaccattaaa
601801 ggtattagat atgtcattga ttgtggttac tctaaactga aagtttacaa tccaaagatt
601861 gggcttgata gtttagtaat aacgcccata tcaaaagcta acgccgacca aagatccgga
601921 agagcgggaa gaactgcgcc aggcactgca tatcgattat acacggaaga tacattcaaa
601981 gaagatatgt acttacagac aatacctgag atccaaagaa cgaatttgtc aaacaccctt
602041 ttactgctaa aatctctgga cgttactgac gaattgagta agttcccgtt cattgataaa
602101 ccacccttac aaacattttt atcctcattg tatgagttat ggttcatagg ggctatagac
602161 actagtggac aattgactcc attgggatta cagatggcaa aatttcccct gcaaccttcc
602221 ctttccaaaa ttttattaat tgcagttaga aacggctgca gtgatgaaat gttaacaata
602281 gtttccatgc tttctgttcc acaagtcttt tatagaccca aggaaagaca gaaagaagca
602341 gatattgcta gaaataaatt ttttatcgcg aaatcagatc acttaacgtt acttaatgtt
602401 tttgaacaat ggagggcaaa taattttagt tcgcattggt gtaacaaaca ttttgttcaa
602461 tacaaatcac ttgtcagggc aagagacatt cgagaccagt tgctaacaat actaaaatct
602521 caaaaaattc cggtcatttc ctccggtaag gactgggata ttattaaaaa atgtatttgt
602581 tcaggatttg ctcatcaagc agccaaaata acaggactac gaaattacgt tcatttaaaa
602641 actggcgtaa gtgttcaact acaccctaca agtgcattac acggattggg ggatttaccc
602701 ccttacgtgg tatatcatga attattaatg actagcaaag aatacatttg ttgtgttact
602761 tctgtagatc cattctggtt aatggaatat ggtgggttac tctacgacat caagcgtatt
602821 aaaaatgatc aggaggccac aactacaggc ctctttggtg aacactatga acatactctg
602881 gacaaggttg aagatgatat tgatatcaat attaggagat gtaaggatat gagagacagt
602941 gtgatacagg agctcaaaat gaccgacaat tcaaacaaag aagacaaaaa gcaaaaaacg
603001 aaaaagcaaa atatactgaa cggcaaagaa aattcaatga aacctttcaa aagaaggaag
603061 cctttttttt agtttatggg aagagcgtgc taataggcaa aatattcata tatgttatta
603121 tatagttata tgcatgcata aaacaaaggg ttatttattg ggtacaaaag aaaagagcat
603181 aactcgtgga gtgcttacat tgagaaaaaa cttttataat agttacccat actgctacaa
603241 tcagattgtt cataaatttc attagctttt ggcaaccatt tcgacatatt ctctattcta
603301 cgagtgcttg ctggatgtgt acttagaaac tccatattca caacaccccc tctattcatt
603361 tgcttttcaa aatttgccat tctttcccac acttttattg actcctgtgg ttgaaaacat
603421 gcccttgaca ttatcatcag gccaatgtaa tcagcttcgg tttccatctg tcttgatgct
603481 ggcattcgca aaaacccatc caatagtata ttgttgatag catgagctcc agtaacagta
603541 tataacacca aacccaaaag agaatatata ggagccttcg acaaattttc ggctgtgtgt
603601 cttgctagct gatgagcaaa ttcgtgtgct aaaacagtgg caatcccatc atcattagca
603661 caaataggta aaatagagct gaatataaag accttacccc ctggtaaaac gaatgcattt
603721 ggtgaagcag ttggatcatt gaccacatga atttcccact tgattccgtc cagtagtgag
603781 ttgtctacac tagggtcctt ataagcagct tcgacaattt tcatgaaaat attctcaatt
603841 ttgatggaca gcggatgctg tggaggtaat atttcctgct gcgtttgtct ccaaattgat
603901 ttgtatgtgt aatttccgat agttaactct aatggacgcg atacccagat gaacctggac
603961 ctatcgctta ccggtgcttt atccaaatgt gtataataaa agagagagca tccaccaaat
604021 aataaagcta agtattttct tgatgactta tcgagaagaa tgcttttaaa cgatgatttt
604081 tgggaatact ctccattatt aaatcgacga tatgaaggac cattgtcata gcggtaacat
604141 cgcgttaact gaacacgaaa tgatacaggt tttaaaaatc ctccactggt cccttttcca
604201 aatcctttga acctgatgat gttgcgtaac atttcttgta ttttatcttt ccatacctta
604261 acttagattg gttgatgtcg cttcgaaaaa ctgctttttg tcttttaagt tctttatatc
604321 ggacgtagaa agaagtagaa atagtaattt gggttaccca tataaaacca acttatctaa
604381 acatatataa acgtatacgg aggattagac ctcaaaagac aattcaggta gttgatcagt
604441 ggacacttga cggtcgcggt tttgtagttc taaatatctc ttcttagtct tgaagtataa
604501 gagccatgct gtaagactta ggattaataa tgtgataata atgcttacca agtcaaatac
604561 cctagatcct gtagattcag attctgcgag actctttaca cgagaaccta taaatagata
604621 gatgaacagc tttggtgtgg ttattatgtt ggcaatggaa aagttgcgta ccgagatacc
604681 gtaaacacca gctatggcac cattagtcaa agaatatggg aagggacata atctcagtag
604741 agctagaatc caatagctat tgttttcttg taaaattgaa gccaatgctt caaatcttct
604801 attcaaatgc acaagctttt ctgctcttga atgcaagatc gtcttgaaca caacgaaaga
604861 ggcaatggaa cctgttacag atcccaaagc tagcgtaacc catccctcaa aactgacacc
604921 atagatcaac ccagtagtgg tggataataa ggagtagcca atcataggag gaaatgcgac
604981 aaagaatatc agaaccatta atataaaatg tgttgacatc ttttctctca aatcgttcga
605041 agtaacaaca actttatgta aaatcgcatt atggaagacg agcaacaata tacccattat
605101 cattagcatt atgccgagga ggacaatgat aatctgttgc cataagcgta gtgaataaaa
605161 ataaaactgt aatttttgaa cattcttcct gatattatgc atcaatctct ctctagggga
605221 catattataa atgtctaaaa aatcatcatc attaacattt acttcgtcat tgaatgacaa
605281 tccagcatta gtaccaaccc tttgtccatt attactattt ggcatgatat cgttgtcaaa
605341 gtcttcgaaa tagccatcaa attcatcatc ctccccttgg cccatattgg catttcctgc
605401 ttcgtaagac tgactcattt gtgtaaccaa tatctttctt ccaccataat aatattttca
605461 aatatgttga aggtattgtt ttagtaaagt ggcttttttt cttagtgcag ctcgagagaa
605521 aacaatgatt tcgatttccg ctttgaaaat gatatgaatg agaaaggcca ttcgaataaa
605581 tacatagatg aaaaagaata tctagaggat atataagcaa gcccgtgttt tcttattgag
605641 taaaactggt ggtgcttttg tgctgcgttg aagaagaagg cctcgatcga aacggtgagc
605701 tctttgtagc ttgagaaggg ggtcttccat caatgctatg acgcctgaaa ttgcccgcta
605761 aatcactatg aatcattgcg tctgaatcga agttacttat cagtctcaat gtaggatggt
605821 cttctttatc cgaatctgtg tataatatgt tgctactgct gacccatttt ttgttcatat
605881 gcctcaagta tctactcttt cggccaaaat gcaatttctt gtctaccatg gcaggtgttt
605941 caatgctggc agaatgtggg ataagttcat ggctttccgg gtcataggtc ttggcatcca
606001 taggaaacat tagccggccc atacttgttt ttttctgcag aattggcggt gggtgtccat
606061 tgattttgct ggattgcctc aacatccttg atgtgggaga agcaactgaa aatgaaaagg
606121 atttggctgg tcgccttgaa gttgaaatag tatctgattt ccttctttgg tgacgcggat
606181 tgagagaagc ggacgtaatg gaataccgcg gtctaaaccc ggaaggtgac cgcccatatg
606241 tgcttgcatt ctcacgtaac aatagcaaag agtttgtcga ttctgattct aataagttgt
606301 catctaaaac attggaaata tgattgtcac ccttggttgg agtcctagtt agcaatgttg
606361 aattttctgg gtttttggac tcatctgacg tttgctctgg agctttaatt aatccaatga
606421 ctgaatcagc aaattggaag ggggttttta aagaggaggt gacaatcatc ctacctttga
606481 tataagaaat cgccttatcc agagcaaatt cctggccaca gtgattttga ataatggaaa
606541 ccttgggcca cgtagctttt gcaccattgg tgatttccct taataaaaat tcttttgttg
606601 ggtttgacaa cagctccttt attctaaaaa gcatacacat gtcgggcaaa atagtgatgt
606661 caccagaata ttgttgagat aataccgatc tcagttttgt aagcgcgttt ttggcaattc
606721 ccatctcact tccaatttct agaatatgaa tagcttcatt ggccataaaa ttgtatatac
606781 ttgataagtt ttgctttaat cttgcactaa attcgtcctc aatttccccg ccaacacagg
606841 atagtgatag tttcaaaaag ggaaatacgt gaatattcac ctggcatgcg ataatatggt
606901 ctacattaaa catttcagaa agacgagaaa tgggcaagtc attgtccaca gaaccatcga
606961 caaatttgac cgaactacta ccagtccatg gtttcctttc tcccgttttt ggatcttttt
607021 cgtaaagtgg gctcgagggg aaaattcccg gtagtgaaca tgatgcacat acggcggacc
607081 aaatcaggac gtttggtgca gtcaaattat tcagcaagcg cggttgttca aataaagatg
607141 ccggcgaaac ggttatattc aaaattttac ccgttctatt gtaagcttcc ctaaatgtca
607201 aatctcccaa aaattctatc attgtattta ccagatgctt gttatcaaac cacgtaccgt
607261 ttttgaagaa cctagatatt tttattaaca aattctcgct ttcacttttc tgtttatcgt
607321 ctttgaaaat gttgaattct ttatccaaaa tatgatttag taaaaccgga atttcttctt
607381 tgtgatggac agataatatg cttgctacaa ttgcaccagc actgctacca ctaatcactc
607441 tgggtaataa atccaattca aatagagtac caaggacacc gatgtggaaa agaccaaaag
607501 ttccaccccc actgagaact aaagcggtac gaccaatatt tcttctcgtt tgttgcagta
607561 tacccaaaag gtaactatca tcaagatcag actccattaa agattctagc gctaacctag
607621 actccatcat atactcgtca attaaatatt tggtgcctac atgggagtgc ctatataggt
607681 ttacattccc catatttccc aggtttcgta cccaattcgt cctaatgatg tacaacaatt
607741 gagcgtaatt cctattcaag cgctcctcac gcattctaga tgttaaatct tttattagct
607801 tgtaatcata caagggactt tccaatttct gcttccattc tgttttccca gtgaggtcat
607861 ccaatctggc gcccgcagaa caccattctt caaatgacat cgcatgttgc ttttgtgaac
607921 agactttgtc aataagaatg tctctttcat agtttcccac aaaaacgttg taaagaaatg
607981 atttgcattt actggctaaa gatgaccctt gcctttcatc ttcgccttcg tctgtctcaa
608041 ccatctcgat atcattattt tcattttctg ttactgtctc ttggtcatcg tcaagtttat
608101 cctcgtttcc agtatccagg ttgaaattta ctttgttcgt agttttgttc ttgccagttt
608161 gcagtctttt accagcatcc tcctccaccc tttcaacatc tgaattatcc ttactgggcc
608221 taataaactt gttcttcgga tttaaaatag gaattatgtt ctgggaagtg cccaggatct
608281 gttcgtaata tttttcgatt agttgttgcg taacaaggag gggcttattt tgtgtagatg
608341 taagatctga tattttgctg ctcattcaga cttttattac atatacctgt actcccttca
608401 ataattatta cagcgctaat ttttttgatc aaatacttga atacaggcct cttttacgag
608461 tacaataatg acataatgac aatttgaatc aaccatactt tataattgtg gtttagcgtt
608521 tcatagtcgc aattatcgta taagaggggt aatatgtcag ccctagttta ccctactttt
608581 tttaaacccc ttaagatctt ttttcctttt ttctaatatt taacctacta atattggtaa
608641 gtaaacctaa tgactttttg aagcgcctag ccctatttct ttcgaaattt tcaattcgcg
608701 tcctttttca attccatgaa taataggaaa catgaaaaaa taagtaaata ataataatag
608761 aaaagctgga gtgttgcaaa tttaagaggt agccttaaaa tatatttctg ctgtgttgaa
608821 tatttaattt atacagctag aataggatat tatagccgaa tttttttcaa gcttcttcaa
608881 agcttatagt gaataacgta aggggaaaaa caagaataaa tttagcaaaa gaaacgctca
608941 agtcaatgta taactcaatc tacgggtccc ccttccctaa aataaatccg aaggtccgct
609001 acaaaactgc tctagaaaga gcagggtttg acactaagcc gcgtaatccg ttcagtagtc
609061 agaggaatgc ttccactgga agtttacaag cttccgtgaa gtcgccgcca ataacccgtc
609121 aaagaaatgt atctgccgcc ccatctgttc cggtcacgat gaagagtgcg tatacggcgt
609181 cttcaaagag tgcttattca tctgtaaagg gcgagtctga catttatccg cctcccgtat
609241 tggagaatag cgagaggcgg agtgtaactc ctccaaagaa tagcaatttt acgtcttcga
609301 gacccagtga catatctcgt tctatttcca ggcccagcga gcgtgcttcg caagaggatc
609361 ccttccgttt tgaacgcgac ttagaccgtc aggcggaaca atatgctgcc tctaggcata
609421 catgtaaatc acctgctaac aaggaattcc aagccgcaga taacttcccc ttcaacttcg
609481 aacaagaaga tgctggtaat actgaaaggg aacaagattt gagccctatt gaaagaagtt
609541 tcatgatgct gactcaaaat gacactgcaa gcgttgtaaa ttctatgaac caaaccgata
609601 acagaggtgt gctcgaccaa aaactcggaa aagaacagca aaaagaggaa agttcaatcg
609661 aatatgaaag tgaaggacag caggaggatg agaatgatat tgaaagccta aattttgaac
609721 cagatcctaa actacagatg aatcttgaaa atgaaccact tcaagatgat tttccagaag
609781 caaaacaaga ggaaaagaat acagaaccta aaattccgga aattaatgtt acgagggaaa
609841 gtaatacacc atctttaacc atgaacgcac tagactctaa aatatatcct gatgataact
609901 tttctggcct ggaatcttca aaggaacaga aatcacctgg tgtgtcatca tcgtcaacaa
609961 aagttgaaga tttaagtctt gatgggttaa atgagaaacg tctttcaata acttcttcag
610021 aaaacgtgga aacaccatac actgctacga acctccaagt cgaacaattg attgctcaat
610081 tagacgatgt ttccctatct agaaatgcaa agctcgatat gaacggcaat tgcctcaacg
610141 cagtggacag aaaggcttct agattcaaaa agtcaagcgc atatttatct gggtatccca
610201 gcatggatat acccgtaacg cagcaaacat caattgtgca aaacagcaat acgaacttat
610261 ccagacaaac tattctggta gataaaggcg atgtcgatga agacgcgcca tctgaatcta
610321 caactaatgg tggcacaccc attttttaca agtttaaaca gtcgaacgta gaatactcca
610381 ataatgaagg gatgggttcg caagaaactt tcagaacgaa acttcccaca attgaagcac
610441 tacaactgca gcataagcgc aacataacag atctgagaga agaaattgat aattccaaat
610501 ctaatgactc tcatgtatta cctaacggcg gcactacgag atacagctct gatgcagatt
610561 ataaagaaac ggagcccatt gagtttaaat atccgcctgg ggagggacct tgcagagcat
610621 gcggcttgga agtcacaggg aaaagaatgt tttccaaaaa ggaaaacgaa ctgtcgggtc
610681 aatggcatcg tgaatgtttt aaatgcattg aatgtggtat caaattcaat aaacatgttc
610741 cctgttatat tctaggcgat gaaccatatt gtcaaaagca ctatcacgag gagaatcaca
610801 gtatttgtaa ggtttgttca aatttcatag agggtgaatg tctggaaaat gataaggtgg
610861 aacgattcca cgtggattgt ctaaactgtt tcttatgcaa gactgccatt actaatgatt
610921 attatatatt caatggggaa attccattgt gcggtaatca cgacatggaa gctctcttga
610981 aggaaggtat cgacaatgct acatcaagca atgataagaa caatactctc tctaaaagga
611041 gaacgaggct catcaacttc aactagcatc actacccatt tgtctttcct agcacacatg
611101 tttcataaca ttcttaataa gattttgatt ttttatatta ttagccagcc ttgttcattt
611161 ataaattgta tagcgcagga aaaaggcatc tgcctatcta tggtatcaac aacattagtc
611221 gtcattagtt agttagttat aaagacatca ttcactcata ttcactacgt tgtcttcttc
611281 tcaacaacta cctctaactg tttttttacg cgtcatttaa ttgtagcgaa tttctatttt
611341 tggacattct cgtaccggtg cattaaaggc taaaagctaa aaagggaaca ggagcctaag
611401 aatagagaat aaggaaattt atttaaggaa aggctaagca atgaaatgtt tcgttatttt
611461 attgtatttt caagaggatg gaagaagaac ctgagcacaa acggataaat aatagacgaa
611521 tataatgttt cttaagacac ctaattggga aacggtaaat gagactccca aatcgagagt
611581 cttaacgata aacgaattga tctctcccaa cctggatact gaatctaaca gccttctggc
611641 gacgccggca aggaaatatt tcaaaacttc aataagtgaa gcgcaagatt ctcctacatc
611701 tgccccttcg cccgatggca atgaggatcc cacatatcaa tacaacgtac aatttcattt
611761 tccaggacca ataacaccta caacacccag gtctaagaat gcagaaatgt ttccatcccc
611821 cacgccccca ttggtttctc ccacagcggt tatcgaggaa gagaatgacg attccgtacg
611881 ggagttttca cgcacgctaa aatcaagact caactgcgca atggttaagc tatcaaagga
611941 acatgagcaa gtagctttga ttcctccacc tccgacggaa aagatacgaa agggctctta
612001 tagtaataaa tttgccgcta agcataggcg ctgtcactcg ttagatgaat ccaaaaagtt
612061 tctgagttct ctggaagatt catccgctca tgcagcgttc ttgaaggcaa tttcgtccaa
612121 acatgccaaa agcaataggg tagacaacgt taacgtttcg ccgttacgtt ggtcatctca
612181 tagaagaacg caaagtacac aggagaattc tttacaagaa gttgttgcta tcgatacatt
612241 attgaagatg tcctcatcgg actgaactaa tgattcgggt ttcgcatata tacatggctt
612301 tggctacttt taggtttata gttcttgctg tttatatcac taatatttag tatatagctg
612361 cgaagaaaga aaaagaaaat attcacctct aggagccaaa aacataaaaa aaaaaataat
612421 taaaaaaaac ttttattgaa tgcttaatta tttagtgacg cgattaccta tataccaggt
612481 tatttatttt ttcttttttc aaaggaaaac aatacaaaat attactgtta ccatttttgt
612541 tactattatt attgtcttta ttactattat ttttctatcg ttgctataat tacaatttgt
612601 ttactctaca acttaaaagg agattactcc agacaacgag ttttgtttta tgtttcctat
612661 tcttttaatc ttggaatttg tatgaaccac tttctaatgt aatggatcca cctctgtaag
612721 aacctctctt cattttattt ttgttcttcg tgaaatcttt acctcttact ctacctaatt
612781 tttcatttgc cttttcaccc catgttccag ccgcgccttt gtaggtgttg tctgtcaact
612841 cccaagcttc gaaattaatc ttcgatctat ctactctgga aaaatgcttt ctttggccct
612901 ctttgatctc gtcggttcca gcaggaatgt tcaatttatt ggcgcttgat gaactggaag
612961 cagatggagt tgattcgtta gatgaggcag gcgtttcttc ggccttggat tcgtctgcag
613021 ttgcttcttt tgtttccaat tcagagctag aaccagagtc tgagtcggaa tccgaatcgg
613081 aggaatcaga agatgtagat tcgtcggaac ttgaatcaga cgagcttgaa gaatcggacg
613141 agcctgaaga gtctgagtcc gagcttgagt cggaatccga atctgaatcc gaggaagagc
613201 tgctagagct ggagctagag tcggagtcag atgaagagtc gctggagctg gagtcggagt
613261 cagacgaaga gtcgctagag ctggagctag aacttgattg agaatctgat tcagaatctg
613321 attcggaatc agaagaacta cttgagctag aacttgagtc agaatcagat tccgaacctg
613381 attctgattc tgaagatgac gatgacccgc tagagcttga ctccgatgag gaagagcttt
613441 ctggttcagt tttagccttt ttagtctcct tagcatcttc gttgtctgat tctcttgctc
613501 ttttcttggt ttcatcttct gattcggatt ccgaagaaga ttcgtcagaa ctagagctag
613561 aggaagaaga agatccactg gagctagagt cggattcact agaagattca gagtcactgg
613621 aacttgagct tgagctagaa gaagaagatg atgatgagct agattcagag tcactgctgt
613681 cactgctgtc actgctgctg ctgctgctgc tgctgctgct gctgcttgaa gattcgccgc
613741 tagaactgga cgaggaagat gaagaagaag aggaggagga ggaggaggag gaggaggaag
613801 aagaagaaga agatttctct tcaatctcct tctccttaac acttaatttt ggcacttcgt
613861 caactttaat tttcttggaa gccattgcta tgtattctta gtgtactgcg acttgggttt
613921 ctttcttgct ttgtataaaa gtgcgatgag ttcaatcatc aagtgaattt ttttttttca
613981 gcctgcattg aaaaaaaaaa aattgtatgc tcgagcgatg ggaaggtttt ttcctcttcc
614041 cgttcaaagc ttcctcggac caactccact ttttctcggc ccgttgtaaa gaaatgggta
614101 agagaactaa attgcaataa gcttcgaatt atcgttttga tccagacata aagagatgta
614161 caaactacaa aacaagagta aaataactcg aacgaagggt acaccttctg taataaaaca
614221 aattcactat aactgcctta ttggagtgaa aaaacaagat tatgtagacc ccctctcgcg
614281 ataaagaaca ttaatgactg caacacccgc acaccacaag gtgaagggca aaggtgaatt
614341 aaccaaagtg aagaggacga cgtagaatca accaggtatc cttgataagg ggaggagtaa
614401 gaaaaaagtg tgtcgaacgt aaatttatgt gtctaatgaa agtatcttca cactaagatt
614461 ataattctcc ttggcaaaac aaaatgacac ctttgtcctg ttttcgttat ctactttttt
614521 ttgtgtcaga tgtcattttg gtctcctacg catccactac atccttgtca caatttgtta
614581 tcagtaacca acttagatga cttgcaccag cgccacatct tcgaaagcgt tgaaacaaac
614641 tacgtaaaca aacaaaaagt caacatcctg tagatgtggc tgcaaaacca cagaatcctc
614701 gtgtgggaga aaatattgat aggaccagag cgaacttttt tgatacagac gtaggaggta
614761 gccgttaccg cattagtata ctatatgcgt acggccgcca agagcccaag aaagagacac
614821 aaaactacgt gggataagct tggggtaacg caatcagtat tgttcatttt ttttcccgga
614881 aaagctaaga gttttctggc gagataagat aacggcgccg aaggcagcgg cgaactgact
614941 tacctccgtc ggctccggcg tacggcacca aaaaatcccg caataacttg acaccaatgg
615001 gctaacggcg tccgcagaac cgtgacgcaa tctgcggttt gtgtcaagac agagaagtgg
615061 gctgcttctc ccctttcaac actcccctcc catggctgaa tactcagacg ttttctgtgg
615121 tggaaatggc atcaaaagtg ccactggctg gcgaatccag actattttgt gtcaaagaaa
615181 catgcgtacc tgcacaataa aaagaaaagg cccgccctac tgacatcctg ttcaggatcc
615241 tcgaagaaca ggaaaaagga caaccgtcct tttcacttca cgttcgcagg gctttcctcg
615301 atataatggc gattacacaa gcggtggcgt cttgaaaaaa gttgggtttc ttatctgtac
615361 ggcgatcact cccctcatat gatagctgtg tagagtgact tgctctttga ttggccttac
615421 ttcttgcatc tatcatcctt tcttttactc tctccaatca ccacaactca tatcattcta
615481 catttcattt tattgttctg tacaattttt aggtttgtaa aatatataag tgatgtacat
615541 atcttctata tcctttccgt ttgtgtctat tttagggttg gcttattacg cattattcct
615601 actttatttt tacttgctta cttgaaaaag aaggtatacc acagtgctgc tccactgcaa
615661 acaatataaa atattatcaa ttattttttt ttttcttctt ttgaattaga tcactaataa
615721 actcttataa tgctcaacca tcccagccaa ggctcagatg atgctcagga cgaaaagcaa
615781 ggcgacttcc cggtcatcga agaggagaag acccaggctg taacgctgaa ggattcgtat
615841 gttagcgacg acgtcgccaa ctccacggaa cgctacaact tgtccccttc tccggaggac
615901 gaagacttcg aaggccccac tgaagaagaa atgcagactt taaggcacgt tggtggtaaa
615961 attcctatga ggtgttggtt aattgctatt gtagagcttt ccgagagatt ctcctactac
616021 gggctttccg caccattcca aaactacatg gaatatggac ctaatgactc cccaaagggt
616081 gttctgagct tgaacagtca gggtgccact gggttgtcgt attttttcca gttttggtgt
616141 tacgttacac cagttttcgg tggttacgtt gcggacacct tctggggtaa atataataca
616201 atttgttgcg gtaccgctat ttacattgcc ggtattttca ttctatttat cacttcgatt
616261 ccctccgttg gtaacagaga cagtgctatt ggtgggttca ttgctgccat tattctgatc
616321 ggtattgcca ctggtatgat taaagctaac ctttccgtgt tgattgccga ccagcttcct
616381 aagcggaaac cctccatcaa agttttaaaa tcgggcgaaa gagtcattgt cgattcaaat
616441 attactttac aaaacgtttt tatgttcttc tatttcatga tcaatgtcgg ttctctatca
616501 ttaatggcca ctactgaatt ggaatatcat aaggggttct gggcggccta tctattgccc
616561 ttctgcttct tttggatcgc tgttgtcact ttgatttttg gtaaaaagca atacattcaa
616621 agaccaatcg gagataaagt catcgctaaa agttttaaag tttgttggat tttaactaag
616681 aataagttcg acttcaacgc tgctaaacct tctgttcatc cagaaaagaa ctatccatgg
616741 aatgacaaat ttgttgatga aattaagaga gctttggcgg cttgtaaagt ctttatattc
616801 tacccaattt attggaccca atacggtacc atgatttcca gtttcatcac tcaggccagt
616861 atgatggaat tacatggaat tcccaacgat ttcttacaag cattcgattc cattgcgttg
616921 atcattttca tcccaatttt tgaaaaattc gtatatcctt tcattagaag atacactcca
616981 ctaaaaccaa ttacaaaaat tttcttcggt ttcatgtttg gatcttttgc catgacatgg
617041 gctgctgttc tacaaagttt cgtttacaag gctggtccat ggtataatga acctctgggt
617101 cacaacaccc caaatcatgt ccacgtttgc tggcaaatac ccgcatatgt cttgatttct
617161 ttttcagaga tctttgcctc tatcactggg ttggaatacg cttattccaa agccccagct
617221 tccatgaaat cgtttattat gtccattttc ttattgacta acgcctttgg ttctgcaatc
617281 ggttgtgcat tgtccccagt gaccgttgat cctaaattta catggttatt cactggtttg
617341 gctgttgcct gctttatttc tggttgtttg ttctggttgt gcttcaggaa gtataatgat
617401 acagaggaag aaatgaacgc tatggactac gaagaagaag acgaatttga tctcaatcca
617461 atttccgcac ctaaagctaa cgatattgaa atattagaac caatggaaag tctaagatcc
617521 accaccaaat attagtgcgt ttaattaact tactgtcttt tttttttttt tttttttaac
617581 catattacgt tgacgggagt tttctgtgct gctgttattt gtttcacaga actctctcct
617641 cttccattgc tatcgaacag ataaaatgga atttctttat gtataattac tattgtataa
617701 tattcagtaa atctaaattt taagctcata tatctaaaca ctacaacatg gaagcagctt
617761 gtcctcttca ggctcactgt atccgtttac tcttatttcg cgtatttgca taccattatc
617821 tcaaatgact tgttattata tcttgatata tattgtatta tagaacaatt tgtgaagaga
617881 ggtccatatt aagatttcct cccatttaca aatagaatag aaaaggaaat atatatgtag
617941 taaaaaaatc gtgatgtata caaactttgg atttgtggag atcgtaataa atcgattatt
618001 tcaacttctt ctttggacgc aattggttgg tgtgaccaca ctttctcttt ctacagttgg
618061 tagctcttgg tggtaatctg gcgtaacatt tacgacaaac agatttgtca cagttgtatt
618121 tggaagccaa ggctttcaaa gatggttcaa tgataccacc tcttaatctc aagaccaaat
618181 gtaaagtgga ttccttttgg atgttgtagt cagatagagt tctaccgtct tccaattgct
618241 taccagcaaa gatcaatctt tgttggtcag gtgggatacc ttccttgtct tggatcttgg
618301 acttgacatt gtcaatggtg tcagaagatt caacttccaa agtgatggtc ttaccagtca
618361 aagtcttaac gaagctgtac aaaattggaa taagttcatt tatggagtaa gcacagacgt
618421 gcgtgcgtac atcataaaga aagaaacttc acgttagtaa aaaatatttt ttatgcgacc
618481 aagtaaatat aactatgtta tgcaaaataa gatggaacaa acaaaccctt cagcacatat
618541 gcgacatttt caatttgctc tacagattta atgtaaactc agaagcttgc cgcaggtaat
618601 agtttttctc aattgctact tgtttaataa attgtgagct tgtcaatcat tttccattta
618661 tgtctttcgt ttatggcttt tttgctatcg tataatcctc atattatttc gaacatagta
618721 ttctgtattc gccgtaacat acatttgcat tttgaacctt tggtggcttt acctcttgct
618781 gaacgggaaa aagtgatata taaggttgct cttatttgtg tatttgagat tatgagttgc
618841 atacccataa tgcctgggat agatgggtaa tggctagtat gaggcggatc atatggcgga
618901 ttatccgcca tatcctattg cggtacttca gaatctgaaa aacatgaaaa aaaaaaaaaa
618961 gttcagcaaa aatggaaaga ttgcacccag acaactacac aaatctatta gaggcacgga
619021 tggaaatagt atttaaaaag gattgtcgaa agatgatatg gcctccgatg agaagaaagg
619081 cggctatcct catccacata tagaacacaa atgaatgcca ataggtaata aatcactaaa
619141 tctactagtt tgtaaaaggt tcgaaataat atgtcataaa tttcgctgtt accttattgc
619201 tcaggcgctt aacgccaaat tgcattgccc atcattgaag aacacaacct aacgcgttaa
619261 tatctcaagc aatgaattca agtatcccta tgcaagaatt taaaaatttc tctctctatt
619321 tgaactgaac cagcattttt tatatctctc cacatatcgc agaaagcttt tctactctca
619381 agaaaaaatt gagggatggg tcaaccttcc atagattcta tatggaataa taaaatttac
619441 ttcttactaa cattatatca gggtgaatat tactgacaaa aataataact taagtcttct
619501 ttataatatg atgatcgacg cgcggggtaa cgcgctcttc ccatctttgt ttcctttcat
619561 tcctcttgac atgacaacaa gagtatatgg gaaaagaaaa ctggaaggca aattgaatac
619621 agacagagat atcaataaaa gtggtccatt gagtcttacg gcgccggaga gatacgctcc
619681 atttacaata tttactgata gatatattgc tgcctgtcta tttttccatc tcttgtgctg
619741 actaggactt aactgatact cgccgaagct acacaaatag tcagtaacgc cacgttttag
619801 gataatgtcg gatcatgata ctccaatgga aagcatacaa aatggtgaaa attcagacga
619861 aagattgaac gccattgcgt cttttttcgg ttgctcttta gagcaggtta aatcatttga
619921 cggtgatgtg gtaaaacacc ttaacgataa acttttacag tttaatgaac ttaaatcgga
619981 gaatctaaag gttaccgtct cattcgatga attgaaggct agttctttaa agaaaattga
620041 tggtttgaag acagaaatgg aaaacgttat aagagaaaat gataaaatcc gaaaagagag
620101 gaatgatact tttgttaagt tcgaatctgt agaaaatgaa aagatgaaat tatcaagtga
620161 gctagagttt gtgaaaagga agctcgatga tttaactgag gagaaaaagg aaacccagag
620221 taatcaacag cgaaccctga aaatactgga tgaaagacta aaagaaatag aattggtcag
620281 ggttgagaat aatcgctcca atagtgaatg taagaaacta cgctctacaa taatggattt
620341 agaaacaaaa caacagggct atattactaa tgacctgaat tctagaactg aactggaaag
620401 aaaaacacaa gaattgactt tattgcagtc aaataatgat tggctagaaa aggagctacg
620461 ttcaaaaaat gaacagtatc tctcctacag acaaaaaacc gacaaagtaa ttctagatat
620521 caggaatgaa ttaaatcgtt taaggaatga ttttcaaatg gaaagaacga ataatgatgt
620581 tttgaagcaa aaaaataacg aattgtcaaa atctttacaa gaaaaactac tggaaatcaa
620641 gggtctatcc gactccctaa attccgaaaa gcaagaattt tctgcagaaa tgtccctaaa
620701 gcaacgttta gtggaccttt tagaatcaca attgaacgct gtaaaagaag aattgaacag
620761 tataagagag ttgaacactg caaaggtaat agcagatgat tcaaaaaaac aaactcccga
620821 aaatgaagac ttacttaagg aattgcagtt aacgaaagaa aaattagcac aatgcgaaaa
620881 agaatgtcta cgtttatcct ctataactga cgaagcagat gaagataatg aaaatttatc
620941 tgcaaaatct agttctgatt ttatattcct gaagaaacaa ttaattaaag aaaggcgtac
621001 caaggaacat cttcaaaatc aaattgaaac attcatcgta gagttggaac ataaagtgcc
621061 cattataaac tctttcaaag aaagaactga catgttggaa aacgaattga ataacgctgc
621121 attgttacta gagcatacat cgaacgagaa gaatgcaaag gttaaggaat taaatgccaa
621181 aaaccaaaag ctagtggaat gtgaaaatga tcttcaaact ttaactaaac aacgtctcga
621241 tctatgccgt caaatacaat accttttaat taccaattct gtttctaatg actcgaaggg
621301 acccttacgt aaggaagaaa ttcaatttat tcaaaacatt atgcaggaag acgatagtac
621361 tatcacagaa tctgactctc aaaaagtcgt aactgaaaga ctagttgaat tcaaaaacat
621421 tattcaatta caagaaaaaa atgcagaact tttgaaagta gtaagaaact tagccgataa
621481 gttggaatcg aaagaaaaga aatctaaaca aagtcttcag aaaatcgaaa gtgaaacagt
621541 aaatgaggct aaagaggcta taataacttt aaagagtgaa aaaatggatc tagaatcaag
621601 aattgaggaa ctacagaaag agcttgaaga attgaaaact tctgttccca acgaagatgc
621661 gtcatacagc aatgtaacta taaaacagtt aaccgaaact aagagagacc tcgaatctca
621721 agtacaagac ttgcaaactc gtatctcgca aattactagg gagtctactg aaaatatgtc
621781 acttttaaac aaggagatac aggacctgta tgacagcaag agcgacatat ccattaagct
621841 tggaaaggaa aaatcatcga gaatattggc agaggaacga tttaaactac tttcgaatac
621901 gttagatcta actaaagctg agaacgacca actgcgcaaa aggtttgatt atttacagaa
621961 tactatttta aaacaagatt ccaaaacaca cgagacactt aatgaatacg tttcctgtaa
622021 atctaagtta agcattgttg aaacagaatt attgaacctg aaagaagaac agaaattaag
622081 agttcattta gaaaagaact tgaaacaaga actgaataaa ctctcccctg aaaaggacag
622141 tttacgcatc atggtaactc aattacaaac tttacaaaag gagcgtgaag atctattgga
622201 agagactagg aaatcatgtc aaaagaaaat agatgaactt gaagatgctc tcagcgaact
622261 taaaaaggaa acttctcaaa aagaccatca tatcaaacag ctggaagaag acaacaattc
622321 aaatatagaa tggtaccaaa ataaaatcga agctttgaag aaagattatg aatcagtaat
622381 aacttctgta gatagtaagc aaactgacat tgagaaatta caatataaag tcaaatcact
622441 agaaaaggaa atcgaggagg acaagattcg tttacatact tataatgtta tggatgaaac
622501 aattaacgat gattccctac gcaaggagtt ggaaaaatcc aagattaact taactgatgc
622561 ttattcacaa atcaaagaat acaaggatct ctacgagact acctctcagt ctttgcagca
622621 aacgaattct aaattggatg aatctttcaa ggactttact aaccagatta aaaacctaac
622681 tgatgaaaaa actagtttgg aggataagat ttcgcttcta aaagagcaaa tgtttaattt
622741 gaataatgag ctagatttgc agaaaaaagg gatggaaaaa gaaaaagctg actttaagaa
622801 aaggatatca attttacaga acaataataa agaagtcgaa gctgttaagt ccgaatatga
622861 atcgaagtta tcaaaaatcc aaaacgacct tgatcaacaa actatatatg ctaatactgc
622921 gcaaaacaac tatgaacaag aactacagaa acatgcagat gtttctaaga cgattagtga
622981 attaagagag caattacata cgtacaaagg tcaagttaag accctgaact tatcgcgtga
623041 tcaactggag aatgctctga aagaaaacga aaagagttgg tcctcccaga aggaatcttt
623101 attagaacag ctagatttat cgaattctcg tattgaggat ttatcctccc aaaataaact
623161 attgtatgat caaatacaaa tctacacagc tgcggacaaa gaagtcaata attcgacaaa
623221 cggacctggt ttgaataata ttttaattac actacgtcgc gaaagggata ttcttgatac
623281 aaaagtgacg gtggctgaaa gagatgcaaa aatgttgaga caaaaaattt ctttgatgga
623341 tgttgaatta caagatgctc gtactaagct agataattca agagttgaaa aggaaaatca
623401 ttcttccatt attcaacagc atgacgacat tatggagaaa ttaaatcaat taaatctatt
623461 aagagaaagt aacataacat tgcggaatga gctggaaaac aacaataaca agaagaagga
623521 actgcaatct gaattagata aattgaagca aaatgttgcg cctatcgagt ccgaattgac
623581 agccttgaaa tattctatgc aagaaaaaga gcaagagctc aaattagcta aagaagaggt
623641 tcatcgttgg aaaaagcgct cacaagacat attggagaaa catgaacaat tgagctcaag
623701 cgattatgag aagctagaaa gcgagataga aaatttgaag gaggaactag aaaataagga
623761 gcgtcaagga gcggaagccg aggaaaaatt taacaggctg agaagacaag cgcaagagag
623821 attaaaaaca tcaaaactct cacaggactc attgactgaa caagtaaata gtctaaggga
623881 tgcaaagaac gtgttggaaa attccttgag tgaggcaaac gcgagaatcg aagagttaca
623941 aaatgcaaaa gtagcacaag gtaacaacca gttagaagca ataagaaaat tacaagaaga
624001 cgcagaaaag gcttcaagag agcttcaagc caagttagaa gaaagtacga cttcttacga
624061 atctacgata aacggcttaa atgaagagat tacaacatta aaagaagaaa ttgaaaaaca
624121 aaggcaaatc cagcaacagt tacaagctac atctgcaaat gaacaaaatg acttatctaa
624181 catagttgag tctatgaaaa agtcttttga agaagataaa atcaaattca tcaaagaaaa
624241 aacccaagaa gttaatgaaa aaatactcga ggcccaagaa aggctaaatc aaccttccaa
624301 tatcaatatg gaggagatta aaaaaaaatg ggaatctgag cacgaacagg aagtatctca
624361 aaagattcgc gaagctgagg aagccctcaa aaagcgaatc agattaccca ctgaggagaa
624421 aattaataag ataatcgaac gaaagaagga ggaattggaa aaagagtttg aagaaaaggt
624481 tgaggagaga ataaaatcaa tggaacaatc tggagaaata gacgtggtgc ttcgaaaaca
624541 gctagaagct aaggttcaag agaaacaaaa ggaattggaa aacgagtata acaaaaaatt
624601 acaagaagaa ctcaaagatg taccacactc aagtcatatc tcagatgatg aaagggacaa
624661 attacgagca gaaatcgaaa gcaggttgag ggaggagttc aacaatgaac tgcaagccat
624721 aaagaagaaa tccttcgacg aaggaaagca acaagcaatg atgaaaacta cccttttgga
624781 aagaaaactt gccaagatgg aatctcaatt gtcagaaaca aaacaaagtg ccgagagtcc
624841 tccgaaatct gttaacaatg tacaaaatcc attactagga ttacctagga aaatcgaaga
624901 gaattcaaat tcaccattca atccgttact ttccggtgaa aaactcttaa agctaaattc
624961 taagtcttca tcaggtggat ttaacccttt tacctcgcca tccccaaata agcacttaca
625021 aaatgataat gacaaaaggg agtcgttggc taacaagaca gatccaccaa ctcatttgga
625081 acccagcttc aacattcccg cctcaagggg tctaatatct tcatcttcca ctttgtcaac
625141 tgatacaaat gatgaagaac ttactagcaa caatcctgcc caaaaggatt catcgaacag
625201 aaatgttcaa tcggaagagg atacagaaaa aaagaaagag ggagaacctg ttaaaagagg
625261 agaggcaata gaagagcaga cgaaatccaa caagcgacct attgatgagg taggagagct
625321 gaaaaatgat gaagacgaca ctacagaaaa cattaatgag tcaaaaaaga tcaagactga
625381 agatgaggaa gaaaaagaaa ccgataaggt gaatgacgag aacagtatat aaaggagata
625441 gtaaaaacaa gggatcaata caaactaaac ctttttcaat gtggaggagc ttcattctgc
625501 cctatgtcaa gaccatttgt aatatacgta caacagcatt cttgtttcat aaagtttata
625561 tatgtataag ctaagatgaa gtcacgtaaa tagctcaaat gccgattttt taatactcca
625621 aacacagaat cctctatata tggaaatgga atcatgaatc ttacggtttg tgttttgaat
625681 gttccaaaca gattttctta gtgttccgat ctctgttcca cccaccaaac gagaaaaaag
625741 taggtcttcg cgaaaactcc agcgacaccg ctggtccttt aagttaaaat aatatgaatg
625801 gtggaagaac ccagatcaac ttgactgaaa caagtctgcc aacatagaca gctaagaaaa
625861 ttgatgacaa gcaaacggga aaagtcactg gatcacacat tgtaagtaga agcagttttt
625921 caatgggaag accgcactgc atagtttact aactatttaa actttccaaa cattagagaa
625981 ctaaagatac cgtttgaaac ggagcgacaa gcgaccatag caaccaaagt cctatctccg
626041 gacccgattt tgaagccaca agattttcaa gtagactaca gttccgagaa aaatgtcatg
626101 ctagtccagt tcagaagcat tgatgatagg gtgcttcgag tgggagttag cagtatcata
626161 gacagtatca aaaccattgt ggaagccatg gacgttctat cataaataat tagaacaccg
626221 tattagtgta catatagtat aagtatctag acggcattca tgcacatcat aacttaaata
626281 tttaaaatag cattaagata aaaaaataaa gagaggtata gttgctaaat gtcctggggt
626341 tgcgtgtaaa taaacaattg tttgctttga gtaaagcaag catgtggatg gtagatgagg
626401 ccttatttac tcccattagc tgggtaacgc agaaagtttt aatatgaaag ggtgacggcg
626461 cttggcgttt ttcttggatt gtagaagtca tgctaggccc ttggagtaag ataagagaga
626521 acaaataaaa gctttggcaa atatcaactc agacgtcttt tttaaagagg atatagagct
626581 ttggtgttgg cctatttccc atcgctgtta aatttccgct tttttgtttt ttttttccct
626641 aaatttgagg aacagctgtt tatattgatt tccttctttc ctggtgcata ttggttgaat
626701 catcaacgct taacgactaa caaattagat ccagagttac agacgggtga gattcatata
626761 tagaccgaag gagtttcaca atccactata ttatgccaga aacctctgtt cagaatccat
626821 taaggctttc tgaaaatgaa aatactcgtt cgatgtttct gtctgcatca cagcagcagc
626881 ggccatctgc cactccatcc ttccctaggt tggtacggaa taccacagca aatttgagtt
626941 tatcagattt tcaagtgtta aatccgtctt ctaaaaggca aaattcaaac tcggtttacg
627001 atgatataaa tagcagtaag aggcgaataa gtagacctag attttcagat atcgaaggaa
627061 aaaataatga ccatacttac ccagaaagaa caacagtcaa ggaatcagag aaaaatcctt
627121 ctcccagata tgtgagtagt tcgaaaaggg ccctgaaaag ggaaaactca gttggaatta
627181 ctcaatcctc tgcattgatt tcgaaatcat ttagtgaaaa cggcggaagc attgcacatg
627241 agaaatggag cccggaaaat atgataaaac cactgaacgt ttcacagaat tcgctagctt
627301 tcgtggatgc agggtcagat gaacagtcca agagtgaaat tgtaggcggt ttccagcgta
627361 aatctaataa tagtcaagaa atcaacgaca aggataacag tgcccgagat caggatttca
627421 ataacagtgg caacaacaac aataataaca atcacagtag caataacaat gacaataaca
627481 ataataacaa cgacgacaac aacaacaaca ataacagcaa cagccgtgat aataacaata
627541 atagtgatga tagtaatgaa agggaagaaa atgattcctg caagccagca agtaataaga
627601 gatcgggcat tgctctaata caaaaattac aagaattgta caaagtgata gttaagcaag
627661 aaattgaatt gcaggagcgg tgctcacaac taacaaactc tcaaaccacc gaactaaaaa
627721 gcttgtggac tatctataaa atcaatacag atcttgttaa caattatgtc acttttatca
627781 ctacagcttt actaccatcc caaccgcctc acgatttggt catcggccaa gaaattgtcg
627841 aaatatatag gatcgaaaga aggctatggg tttacggcac gataacattt ctagacgttc
627901 taaagaactt ttctaacttc atggatcctg aagtttgctg ccaatttatc actcacgtct
627961 ttgtttcatt atcaactatg atttctgaca taccgtccaa atattctatc acttggttac
628021 aaagactagg agacttatca agaatggcta tagcactata tccctcgagt tttatcgatt
628081 ggaaactgag tgctgagcat tggtatactg aggcgatgaa atacatatac aatcatggaa
628141 agctatatta tcatatgtct accgtacagc aaaacactct tgaagctttt gtaaatttgg
628201 ggaaaagcgt cttttgtcag gaaacattca ctccgtctcc gcaatatatg caattggtta
628261 ttgataacat ttatcaaaga gcctttgtag aaagaaataa tggcaatctt agaaactctt
628321 tattaattga gtatttgaaa catagtgaag ccatgctatt acccagtttt ttagaaagtc
628381 cagatttaca aaatgtcgtg ttgagctatt tcattgaaaa gttcggtata gatgcaaacg
628441 gttgtaacat ttttaacgca gaagatatgt ttgttcagaa tcctgatttt ttcaagtatt
628501 tcttcaggca tggcccctct tttgcacaat cgcatatttt acaaattgtt ggatttggag
628561 agccaaaaaa cccatttgca attttatttg aattgccgaa gtatttgaag gagaggaaag
628621 acaagaagga acgtaaaaaa tcttcaaata atgactcctc cgtgacggaa agttcaacgg
628681 gcaatagccg aaatgacaac gaagatgacg atgaaataat gagttctacc acttccatat
628741 ctgatcacga tctcttagca gaattcttca atgacatcga taccttaagg cgtccgatac
628801 tgccttcaat gctaacaaac gaagcatggt tggaaacatt aaagtttcta aatatgacct
628861 cattaaaatg cggtataata gtgcttcgga agtttctaca tgggccttta ggtatcgcat
628921 taccccatat cttaccatgg atatacttta tcatctcaat ttgtttgaaa agcagccaat
628981 tgagtgatcc agttagtaaa gaattctgga tgattattgt taagagagct tttccatggg
629041 atacaatggt tacctttatg aatgttttga ttgtgtattt attggataac caaacatcga
629101 actctattat tggagattta tgcgatgact acgataaatt aagcctttct gaacttttag
629161 aattattcaa tgaaggcgaa gaattaccag aaattttggg ctgttgggga acattgtggt
629221 ttgacacaat ttgcgaaaag aatacgcatt cgattagtag tgaagataat tttcaagaaa
629281 tcggtataaa agattatatg gcattggatt cgccgacaga tggaattata tttgatgaaa
629341 aggacgaaaa tggtgaaaaa ttctggaaaa gggcatgcag aaccatattt ctttttagag
629401 agctgtcaag aagttttcca ataggcgtaa taatcagaaa cgatccgttg atatatcgtt
629461 catcatttca aaatactaat atattgggaa gtttagtctt caaactcgaa cccttgtgca
629521 atatacacaa caatatacca gtattaggtg ccctggaaag tattattgac atatctgagg
629581 caagaagtga aaacaacact gatctgcacg ctgtgccgga actaagtgtc aacgagggcg
629641 ataatatctt ccactatgtt ggctacaaga aacttcgtgc cgattatacg tgcttcgata
629701 aaaatggaga atttttaagc gcctcgcttt acactacatg gtatgtcccg aacagcaaca
629761 acactaacat agaggacaac atcaattata acagcgaaaa ggaaaatgaa ggtctatttc
629821 tggaatgtat aaaatctgat tatccagaaa tagattttaa aactacatac tttgtctttg
629881 atgcaacttc ttggctaaga cattccgcac gcatattcaa gctagctcaa aacagactgc
629941 taagatttgc catttgttta accacattcc aagagctgag atttttacga aagtcaaagg
630001 acgaaaacgt catggaggct gccacaagag gtataataac tataaggcag ctttactatg
630061 agaataaagt attaccccta agattcacag gtaatgtagc gacacacatc gaagagaact
630121 tagaatttga agaacaaata acatggagga cacatgtcga cgagtttgtc atcgaatccg
630181 taatgaaggc gcaagaaaaa ctagagagtg ccagcgaacc gcgtctttcc cctcgccgct
630241 ttaactacgt agttctgata tctgacgacg acgccatgaa gaaaaaagca gaagaaaaag
630301 aaataaaaac gctaagcaca cgatttgtgt tttctttgtg cacaaaactt ggcgaacagc
630361 gccatctgtg tacagactga tcgttcgttg tacgtacatt tacaacaaca ccaattctac
630421 tcaccgccat aaataacact ttaattttaa tatatacttt tatatgcata taaccaactg
630481 acttccatac aattctgacc agagcacttg ggcagagccc ccacccaggg ccttgtcgga
630541 aaaaatcgga atatcccaca cgatccaccg gagaatatcg ggacgctgac gggtgaatgg
630601 agatctggat ttcctaattt ggatacatct cttttctttt tttgactcac aataggaaaa
630661 aaccgagctt cctttcatcc ggcgcggctg tgttctacat atcactgaag ctccgggtat
630721 tttaagttat acaagggaaa gatgccggct agactagcaa gttttaggct gcttaacatt
630781 atggataggc ggataaaggg cccaaacagg attgtaaagc ttagacgctt ctggttggac
630841 aatggtacgt ttgtgtatta agtaaggctt ggctggggat agcaacattg ggcagagtat
630901 agaagaccac aaaaaaaagg tatataaggg cagagaagtc tttgtaatgt gtgtaacttc
630961 tcttccatgt gtaatcagta tttctactta cttcttaaat atacagaagt aagacagata
631021 accaacagcc tttcccagat atacatatat atctttattt cagcttaaac aataattata
631081 tttgtttaac tcaaaaataa aaaaaaaaaa ccaaactcac gcaactaatt attccataat
631141 aaaataacaa catgtcccct tctaaaatga atgctacagt aggatctact tccgaagttg
631201 aacaaaaaat cagacaagaa ttggctctta gtgacgaagt caccaccatc agacgcaatg
631261 ctccagctgc cgttttgtat gaagatggtc taaaagaaaa taaaactgtc atttcatcaa
631321 gcggtgcatt gatcgcttat tccggtgtta aaaccggaag atctccaaag gacaaacgta
631381 ttgttgaaga acctacctcg aaagacgaaa tttggtgggg tccggtcaat aaaccatgtt
631441 ctgaaagaac atggtctatc aaccgtgaaa gagctgcaga ttacttgaga acaagagacc
631501 acatttatat tgtcgatgca tttgcaggat gggatccaaa atacagaatc aaagtccgcg
631561 ttgtttgtgc cagggcttac cacgctttat tcatgacaaa tatgcttatt agacctacag
631621 aagaagaatt agcccatttt ggagaacctg attttactgt ctggaacgct ggtcagttcc
631681 cagccaattt acacacccag gatatgtctt caaagagtac tatagaaatt aacttcaaag
631741 caatggaaat gatcatttta ggtaccgaat acgccggtga aatgaaaaaa ggtattttca
631801 cagttatgtt ttacttgatg cctgtgcacc ataacgtttt aactttgcac tcttccgcca
631861 accagggtat tcaaaacggt gacgttactt tattctttgg cctaagtggt accgggaaaa
631921 ccactttatc cgcagaccca catagattgt tgatcggcga tgatgaacat tgttggtccg
631981 accatggtgt cttcaatatc gaaggtggtt gttacgccaa gtgtattaat ttatctgccg
632041 aaaaggagcc tgaaattttc gacgctatca agtttggttc tgtattagaa aacgttatct
632101 atgacgagaa gtcgcatgta gtcgactatg acgactcttc tattactgaa aatactagat
632161 gtgcctaccc aattgactac attccaagtg ccaagattcc atgtttggcg gactctcatc
632221 caaagaacat tatcctgcta acttgtgatg cttcgggtgt tttaccacca gtatctaaat
632281 tgactcctga acaagtcatg taccatttca tctctggtta cacttctaaa atggctggta
632341 ctgagcaagg tgtcactgaa cctgaaccaa cattttcatc ttgtttcgga caacccttcc
632401 tagccttgca ccctattaga tacgcaacca tgttagctac aaagatgtct caacataaag
632461 ctaatgcgta cttaatcaac accggctgga ctggttcttc ctacgtatct ggtggtaaac
632521 gttgcccatt gaagtacaca agggccattc tggattctat tcatgatggt tcgttagcca
632581 atgaaacgta cgaaacttta ccgattttca atcttcaagt acctaccaag gttaacggtg
632641 ttccagctga gcttttgaat cctgctaaaa actggtctca aggtgaatcc aaatacagag
632701 gtgcagttac caacttggcc aacttgtttg ttcaaaattt caagatttat caagacagag
632761 ccacaccaga tgtattagcc gctggtcctc aattcgagta aacgaaacat gttcgttcga
632821 tatgttcaat ccaaaaaaaa aaaaaagaat tagaattatt tcgacatcat aaatgttcgt
632881 aatatattat tttgtcaatt ttttctcttc ccatttcagc ttttttttaa taactgaaac
632941 tggatcaaca agcacatgtt tttctaatta atctttcaaa catatttatg tatatacata
633001 aggaaaattc aaaaatccga tgcaattaac agaattcttc ttcatagttc tcttcatcca
633061 ttctttcgta gaataagacg tatacctcat cgctagacat ttctgttttg ccggcttcaa
633121 agttgttgcg atccttgcga tgttgctgta tataatcgtc atcaaatgta acccaaactt
633181 gtctattcag tccaatttca tggctctttt ctttgttcac aacagaagta tagtgtccat
633241 tgataaggtt accggaatga ttcaccgttc catataactt gtatcgaatc actttaccgt
633301 tctttaaaat aatgttcaat atcaaagggt aggttattac agtgctgttt ttttttgtta
633361 aatcataata gaaccttgat aaatgaatga caagtatcgg aggtaaaact ataaagtcta
633421 aactcttaat cgtggttaac tttttagaat ttcgcttctt tgcatttttt gttgaatcat
633481 cgctgctatg gtgatgatgg tgatgatggt ggggtgattt tgaccttgat ctggaatgaa
633541 aaccgaatat ggttgatttt ttcttctggc tagtaatttc ttcttttttg gatttagaat
633601 cagtaattct acaattagga caatcccaag cattgtcgcc tgacagttct tcatcgcctg
633661 taaataagtt tatgcaatcc tctaatttaa tttttctcga cttacttgta aagctataca
633721 atgatagttt tggaatcgca agtgacagaa catagaaggt agaatagcta taagaagaat
633781 taccacagcg ctgacatttc aaaatgttct ccaactgccc tcgatatatg tgatcaattg
633841 gagataaacc atcagtaata acatttctct cgtaccattt ctcgtatttg gatgggttaa
633901 cttgtaaagc attcgcatca tatgacacta gatctggata atacttgaca acattttcgt
633961 tcgagagctc ttcatgtatt cgtgctaaaa ctattagtag aaattcctgt gtatcctgtt
634021 gatcatctgg gatgttcaaa tctggcctta acttcttgca catttttaag aatctatttg
634081 gtataatcgc tcttcctcca ttcaaataca tttttttgaa caaaacgtaa atcgagcggg
634141 aaagttggac ttctttcgga tatttgttag tattgaggaa tagcctatat ttcttggtta
634201 aaaacaaatc ccgaaataag gtagtgccaa acagacattg aattatactg ttaatatagc
634261 atgtattgca tggattttgc aggccagtaa tagataactc tgataacaga tcattagaat
634321 cttcaattac tggtagattg taagctttcg gggccgaaga ttctatggcc tcgatctttc
634381 cttcttcctc ctttggcttt tccaccttgg ataaagagga tgaagaatct tggctagaat
634441 ctctgatttg tgacgaaacc tccaaggagt gcacgggggg agcagttgct ggactagaca
634501 gcgttttgaa taatgcatcc tttccagtac tgagttttaa atacgagggt tttgataatg
634561 cttctttgct tgtgtagtac gccacttcag aaccagcttc caatttatta cttgatgcta
634621 tctgattact ttccctgact atgtcctctt tcgaattatc atttgttggt tttgttagct
634681 cattcggtat ttcatgtagt gagccatcaa acttgttatg tattgacaaa gaggccatat
634741 gaacaggtaa aggccgtagc ggtaaggagt aggctctttt tctttttatg gtcctgcaaa
634801 ttccgtttga ctccgctaaa taccggtcaa caataacagt actttcatct cttaccactt
634861 ttaacacata acccatcacg tgttcgtctt gatagtcgtt ttttagcttt gcgtaactgc
634921 tgtagagatt atttcttgtt tggaattgta acgattgtgg aataataagg tacagataat
634981 aacaaccaat aataaatgct gtcaaagctt ccatttcctg attgatttct aaatccctca
635041 ggtaaacatt aaacagatga gcagcatggt ctaacaatcc tcttaagttc tttagccgta
635101 attgcgaata aaactgttta atatctactt catatacttt tcgaactagg tttagaattt
635161 gatctgggtt taataacatt gtctttatga cttccgattt agcgaaaaga aaacggaaag
635221 taagatcaat gccacggtta tttagtttac tgaagatcct gaaagactac tagcagtagc
635281 agtaaccttt cagagcttat aatcaaccta atgattactc agcgcacaat ctaaaagggt
635341 ttctcaacta attctcgaag aaatgtcaat ccctttttta agcactccgg aaaaacttta
635401 taatagatgt ggggaaatca cctttgacga tgtgcaacgg agaaactatt tttttttttc
635461 tttttttctt tttttttttt tttttggtcc gaacaatgcg atgagccaga cgaagaaaaa
635521 aataaaaaat gagaatgagt aattatgtta agacctttag aagaaatagg gtccagtcac
635581 agaataaagc cccaggaaac tttaaagcaa tcgaaattaa ccagctatat ttatataata
635641 agaaattttt cttattagtt tactataaag gactagtgta cgttttttgt gtttaattat
635701 ttgctttctg ataatccggt ttgctgattt gaatcgttct ctgcaacaat tgttgatctc
635761 tagtggggta aacaaaatta gttttgttta aaacttttgt tgtagcgttt ttgctctttt
635821 ttttttatcg cagaatacat tttatcgaga atgtcgaata taagtaccaa agatatacga
635881 aaaagtaagc caaaaagagg atccggcttc gatttacttg aagtgactga atcacttggc
635941 tatcagacac acaggaaaaa tggaagaaat tcatggtcaa aggacgacga taatatgcta
636001 cgatcgctag taaacgaatc cgcaaaggag ttaggctatg agaatggact tgaagacgta
636061 aaaacaattc aacaatccaa ccatctttct aaatgtattg cttgggatgt tttagctaca
636121 cgattcaaac acaccgtaag aacttcaaag gatgtaagaa agcgttggac aggatctctg
636181 gacccaaact tgaagaaagg taaatggaca caagaagagg atgagcagct cttgaaagct
636241 tatgaagaac atgggcctca ctggctgagt atctccatgg atatccctgg aagaacagag
636301 gatcaatgtg cgaaaaggta cattgaagtg ttgggacctg gaagtaaagg tagattaaga
636361 gaatggacgc tcgaggaaga tttaaatctg ataagtaaag tgaaggcata cggcacgaaa
636421 tggagaaaga tttcgtcgga aatggaattc agaccaagtt taacgtgcag gaacagatgg
636481 cggaaaatta ttactatggt tgtgcgagga caagcatcag aagtaataac aaaggctata
636541 aaagaaaaca agaacataga catgacagac ggaaaactcc gacaacatcc aatcgccgat
636601 tctgatatac gctcagattc tacaccgaat aaagaagaac agttgcagct atctcaacag
636661 aacaaccctt cattgataaa gcaggatata ttgaatgtta aagagaacga atcgagcaaa
636721 ctaccaagat taaaggataa tgatggaccc attttaaatg acagcaagcc acaagcatta
636781 cctcccttaa aagagatatc tgcacctcca ccaatcagga tgacgcaagt cggtcagact
636841 cataccagtg gtagcattag gagcaaagta tctttaccaa ttgaaggtct ttctcaaatg
636901 aacaagcaaa gtcctggagg aatctcagat agcccacaga caagccttcc cccagcattc
636961 aatccagcat ctctcgatga gcatatgatg aatagtaata gtatttcaga ttctccgaag
637021 catgcttatt ctactgtgaa aactagagaa ccaaattcct ctagcacaca atggaaattt
637081 acattaaaag atggtcaagg tttgtcaatt tctaacggaa ctattgacag cacaaaatta
637141 gtaaaagaat tggttgacca agctaagaag tactctttaa aaatttcgat acatcaacat
637201 attcacaatc attatgttac atccacagac catcctgtca gcagcaatac tggattgtca
637261 aatataggaa atataaatgg aaaccctcta ttaatggata gtttcccaca tatgggtaga
637321 caactgggaa atggtcttcc agggttaaat tcaaatagtg acacttttaa cccagaatat
637381 aggacttctc tggacaacat ggatagcgat tttttatcaa gaacacccaa ctataacgca
637441 ttcagcttgg aagcaacttc acacaatccc gctgacaatg caaatgaact tggttcacaa
637501 agcaatagag aaacaaacag cccgtctgta ttttatcctc aagcaaatac attgatccca
637561 actaattcta ccgctacaaa taatgaaatc attcaaggaa acgttagtgc taatagtatg
637621 tcaccgaatt tcaatggaac aaatggcaag gcaccaagtt cgacggcatc atatacaacg
637681 agcggttcag aaatgccacc tgatgtaggt cctaatagaa tagcgcattt caactatttg
637741 ccaccaacta tacggcctca tttaggctca tcagatgcga caagaggtgc tgacttgaat
637801 aagttactca atccatctcc aaattcagta agaagtaacg gcagtaaaac taagaaaaaa
637861 gaaaaaagaa aaagtgaatc atctcagcat cattcttcat catctgtgac aaccaataaa
637921 ttcaatcaca ttgatcagtc ggagatatca aggactacat ccagatctga tactccattg
637981 agagatgaag acggcctgga tttttgggaa acgttaagat ccttggctac tacgaatcca
638041 aatcctccag ttgaaaagtc agctgaaaat gatggtgcca agcctcaagt ggtacatcaa
638101 gggattggct cacatacaga agatagcagc ctaggttccc atagcggagg atacgatttt
638161 tttaacgaac tgttggataa aaaggcagat acactgcata atgaggctaa gaagacgagc
638221 gagcatgata tgacgtcagg aggttctacc gataatgggt cagtcctgcc actgaatcct
638281 agttgagaag gcaaggccga aaaaaaacac aaatctttca attgtttaac atattagttt
638341 tgtaataagc ataagtgtat attatacata gcacaagatg gataatattc tctgaaaaaa
638401 acgtgtagtt tcatgactcg catttttttt tttttttctt tcatgttgat taacatactt
638461 gaattctgta tttaagctgt ataaaaagtt gttctatttc atatacggcg attttgcata
638521 attaagaact ttgccttgta cactatttta ctagggtatt cttccaagat ttctcttctt
638581 attttttccc tttataagtc attgtagcaa cataatttcc tggaaatttt aagggaatat
638641 atttctttcc gcccacaaac acaaagggcg tttagtaaat tatgcggcga tgtataaaag
638701 agaaagcagg caaaaagaaa atgaaaaatg agactatgaa ctttaagaat tatgtcttga
638761 ctaatttttt aaaacccatc atccatgaag agttctgttt gtattgttta cgtttgatgt
638821 ttgaagtgaa tttaatagaa ttgttcctct ttttttcttc tttttttaac tataatataa
638881 tgtttagtat atcaacagta ctatttaggc cttagacttt ctatgaactc tctcttactc
638941 tgtgagtagt tggtaaattc gttttcgtat tgatcttcct cagcaatttc cccgatattg
639001 cccacatcat agttattctg taatttgtat aaatccttat ctttatctgt tattgcagac
639061 ctgctatcct ttaccgagtg gtcagcatcc attccttcgt tatctttatc aaaagtgttt
639121 ggtaactgtg attgagccgc acttttgggt gttgcaaaca catcctctag ggcatcgcgc
639181 ttatttaccg atgttataga ggaattcctt gtatggaagg acgcgtttga aatgttacca
639241 tttaaaaacg aggatgaagc tctccttggg taatacgaac caaagtcctg attctgcaaa
639301 tttcttatca gattttcatt actagattgg cgagtattat gtttaagttc tatcatcgaa
639361 gctttgtttt ggtcattgct agtattagta tcactggaag gatctgcgaa aaagtttggt
639421 ccttcatcag aaataacagg gaccatctga tcataaacgc tgatctgtct ctttgttata
639481 tgccgttggg aagatgataa ggaaacattg gagctgttat ttatacttgg taaatccaca
639541 acggacttct gcctggcatt attgccgtag ttattatttc gtacttgaag taaatttatt
639601 ttcctacggt atgctggcac atagtattta ctattctttt tccctaacgg tttctcttga
639661 tctcgcgatt ttccatcttt ttcttctgga tgagcagatc cttccgatga accagaagtg
639721 tgatcaggat tttttagctc ggagctggct agtgctgctt catctttact gtctcttaag
639781 ggtccaaaat tgtcaaagga cacgaaacca ctttcatcat aaatagccct ttccaattct
639841 ctatcgtctt gttcctccct cttgtatctt ttttgtaggt taaaccagaa acatactgct
639901 attataatac ctacaccgac gggtataccc accgcacaac ccaccgcaac tgatgtgctg
639961 gcagtcatct cttttacttc ttactacgat gagctcccaa aaaaaaaata tatccctgat
640021 aaataacaca aaactaagaa gccggaccta ggtgaagagt aaaataagga ctcgaaattt
640081 tgtctaatac tcaataactc agtacaaaaa ctgcctcaca gtataaaata tccaacttag
640141 agatattcgt tttaattgtc ccgagcaggc aaacgataac tgatccttag tcacaataat
640201 aagtctatgc tttctgttga aaaagaacaa atagcgagcg agtcagcaag cagaatctaa
640261 agaggcttgc aacgaatggt aggcaaagaa tttctaaccc gaaacctcaa gcgaatggtg
640321 gattccttac ttccaatctt ctaaaagtct ttaactctga tttcgaggat cagtactttt
640381 tctatggttt attaatatcg gcctcgaaaa gtttgtcgcg agaatttggg cacatgtgac
640441 ccggaatgta tattgagtaa tataagaatg agaacaataa tgtcaataat cacacgtcgt
640501 tataagcagc tgaaaaatta taagataata tcaaaaaaaa tgctacagat caactccagg
640561 cttgcagtta ttgatggatg gctggtagac actgtgaagc gaaaaccaat aaattttcgg
640621 agtcctgaag taagattact gttacccaat gacgatgact acaaaaagct atcacaacaa
640681 aacttggtgg actggacgcg attaaagaag gattctaatt cggtgctcgt tggagtgaaa
640741 tctatggaac tatttaaaca cataaagcta gttttgcgag agtttttctt gttagaagat
640801 ggaagaataa ttctgaagag gatcagaagc aaattacgtt acaaagttgt caagaaatta
640861 acttgtaaat gctgcaggtt atatttacca aaatggggca ccgtgtacat acatccgatg
640921 ctaaaagata aagaaaagcc cttagcgggg gtatgtgaat tttcattgga tgtaaaccct
640981 gatcgggagt atccccttat tgagatcaat gttagtcatc aatacattat aattgagggc
641041 ttccttctat acttaaatga aaggaggctc tataggtgga acgataacaa tttgaggagt
641101 caggttggct taacaaaatg ggcccattta agaaaaactt acaatccggt aagccttgac
641161 atactttata gtttgaattc aaatttttat tttgtaaagg atgatctgct atttcaatta
641221 ttaggaaaga gggtatttgt taaattttgt aaagtaatgg aaaatggaaa atgcggtaag
641281 gctccactgt ggtatcgtgt gaagagaacg acaactgcca aagcaacaca tattgcatat
641341 gccatatcaa attcaacagc cccagattca ttcaaaagta aaaataacga ttataggttt
641401 attgtcaggg aaaagccaat tgtggagaat actatctcca acctggatta ttcagacata
641461 aaaaaacagc agtttactga agcagaggtt gtaaaaagaa agatctcagc agatatttct
641521 caaatagaga atgtgcatac gcaatttaat agtcaaaagg aaaaaaataa tatcagggtg
641581 aataaggttt ctagcgaggt cctagatcaa atttcgaaat ttcctgtgtc cagagtcacc
641641 ttactgttga tgtctgctgg tcaagataaa aattatattg aacttgttga agaattggca
641701 agaaggttgg aaaaaatatg catagaaaaa accacacaat ctttagaaga gataagggat
641761 acttttcagg cgaatcctga gatgcaggct agctttgata aggaatatta ccagagcatt
641821 gaagaatata aaattacact cgaacttatt aaggaagacc ttttgattac tctgataaaa
641881 caaatggaaa atatgtgggc agctgaaaaa aagtttagta cagaggagga gtatgtttcg
641941 ccgaggtttt tagtagcaga tggatttcta atcgacctag cagaggaaaa accgattaac
642001 ccaaaggatc cgcgcttact gacactgcta aaagatcatc agcgtgccat gattgaccaa
642061 atgaatttag ttaagtggaa tgacttcaaa aaatatcaag atcctatccc gctgaaagcc
642121 aaaaccttat ttaaattttg taaacaaata aagaaaaaat tcctacgagg tgcggacttc
642181 aagttacata cattacctac agaagcaaat ttaaagtatg agccggagcg gatgacagtt
642241 ttgtgttcct gtgtccctat tcttttggat gaccaaactg tccaatatct gtatgatgac
642301 agcattattc ctgaatttga agcaacatct tcatatgcaa caaagcagtc aaagtgtggg
642361 cggaaaatgt ctttgcaaat ggagcctgac ctcctttttc aagaggccat tagacggatg
642421 cgacatttaa ctgcttatga cgttttgaga agaaactata ttgcggcatt tgaggagcta
642481 tatatgggaa actgtaacga ttaaatagtt ggtaagatta tcagttatgg ataccaacat
642541 ataagcgggt gatgtctcat ttcaatgagg tcagataact ggtacagttt cgcctttaat
642601 acacttgttt gacagaaact tgtttttaat tgcttgatta gctaagtaac tcgagccgta
642661 ctgtagtacc gttaaatata tattatgtag gacttagtag aatatactaa taatagatac
642721 tgcaattgat gatcccaatt actgttttat tgactaactt tcactgaaat gttttcattc
642781 tctgatttta tatttagttg gcgaactagc tcatcctaat tataattaaa cttatatata
642841 gcataaaccg acaataatgc gtgggtggtc ctccatgccg aatttgtgaa ctgaattatt
642901 atctaagcac tggatcgatc accttaagat gatatattat ttataactaa aacgcagcag
642961 cattacactc cagagtaact cctgaatttc gtcatggcat gtacttatac tatataacca
643021 acaaaggatg actgaataag aaccaaatac ttttcaagag ataagatacg cgttgccatt
643081 gttcgcaagg cagatcaaga agcttcctag gcctgtgaaa aaaggaggaa aaaagaaatg
643141 aattttctag ctgtatttag attggatttg aggttcacta gtataagcaa cagctccagt
643201 tctttagtca agtgccagct tcccttgaaa tattaacctc ccttttttct tcgtaaacca
643261 ctattatgac catcggcctg ttaataagga gaaaaataga aaactgaagc aatagcggta
643321 tcataaagct gaccgtgtaa agtcaccact aacctcccaa taaactcttc caactctgtt
643381 tttttcaaag ctagtggtgc atttgaacgc tatttaggat tccgatctct tcagaaacat
643441 gctgatttag aagtagtcaa attacttata ggcgtgaatt tcgaaattga tctcttaagc
643501 agaatttagt tgtatcaaac tatattcgtt ttggagcgca tatactttac atttcgatgc
643561 gtttaacgtt gcctctgttc ttttcctatt aattctatta gataagttta tttccatctc
643621 atataaagaa gaacctgtcg aggttatatg atctcttttc cgtcttttta ccgattctgg
643681 ttagtgtatg cttcatttga gtttcttgca ctgctttgcc gaccaaatat ggaaatcatc
643741 tattttaact ctattattga agaggctttt cctggcacat ataaatatga atataaatgt
643801 tgtgcggctg taatatttgg ctagaattac cagcctgatt gcgggttata tattgccttc
643861 ttttggacat ttactcccgg tgtaatgttg gcagcagtag tacctatacc tgtgtgccac
643921 ccgtttggat attactataa cttcaaaata tgggaggatt actttctcga aagttgctaa
643981 aaaaatcatt cgggaatttt cgctacagat taatcaaatg tagctcgaca gtcttcatat
644041 tatgagttta aaagttcttt aatattcttg tacatctcaa ttgttatgtc aaccaattac
644101 cagttaaaaa gagagaaatt ttatgagtta ttagatgatt atgcggtgca gaacattgag
644161 gttcctcgtg ataatgataa tacgcacagt tagagagcaa gttagaaagc agattagaga
644221 gggacaagaa agataatatc ttcagttctg taaggctact tttaaaccaa atgagccaga
644281 agacttctct attcgtgagc gtcccaaaag ttatggtcat tgccagtgga gacgaagctg
644341 tactttttac tgcttcacct gtgttttata tagatagctc ataaagagat attgacacca
644401 aactcaaacg aaagcttaca attccgcatc agcattgaga ccctatattc ccctcatcta
644461 ttccaaataa gaatcatata aagaattcac taggcacaga taactgctga tttatagaca
644521 taatcccttc gcatccacgt tagcatgatt ggtgacacgc tttctgagca ttagcttgcg
644581 ataggtttcc agcatctcca gttacaatca tggataaata cacaaggcga cgttcaaaca
644641 tgactgagga aatgcagtat ttaaagctta ctctttcctc agttgagtac ggtaaaatcg
644701 attaacaagc catttcaata gttataattt ttttttttgg tcatggaaga cctgaactaa
644761 agtgttttag taaaccaatt ggagtgagag tttttcattc cgaagattct ttatctcaaa
644821 atttctttat cgaaagacac ttctgtgtca ctgtccgttc aatcagtcag atagttccaa
644881 ctccgatgtc ttccaatacc tcaacgaaga ccgaaaaata aaaggtttgt ttgacggagt
644941 gtgttgatta gtgcattggt gacgtggggt agcaaaatcc agatacttct attttttgaa
645001 aaagaaaaga gagagtgcta gaatgttttc acgtttatca gtacacgaaa aacaaaacct
645061 gaagcaaatg attaccataa ctattgtcca cttatgggga agttgctaaa aataacacat
645121 tatttactaa gggaacacaa attgctcata gtatacttga ctttttttac ttaacttttg
645181 cagcgattgg tgatgaaatg tttcaaaaaa aaaaaaaaaa tcgaaaatcc attgtattgc
645241 ataagaaatg gcgaatttta ggcacgaaat taacttacat ctctccattc ctttcctcat
645301 gaaagaaccg ttatgttagc tagccctgaa cttcttattt tggaaggacc ctcacctcaa
645361 ttttcaaatg aaccgcggac ttcactttct acggtcgttt cttcaaaaat ctttacaacg
645421 tatatcgcct gttgcattgc ctttttcgga aaaccttatt ttacgacaaa ccttttttag
645481 gattaaagtt taaaaaattt cttcgtctgc ctcaaaattg cgcagcttta agcttccaga
645541 atgttttaca cgaaataccc tagcgctgca tttctttttt tcctcagttg cggtagtaga
645601 aaagtattac atcagcacga gtaacaactt atggtgtcag tttcataatt tcacgcacta
645661 aagttaattt ccccttttgt tcaaaaactt tcaggaggtg tggccatgat ggacagaaag
645721 aatgttatgc tttaggatta ttgtacaatt atttagattt gctaaagcgc gtcttatagt
645781 aatcgtgcag taaattttgt aattcagttc cagttcactt tatcatgata gtgttttatc
645841 agtttcgaat ttttggcaca cgaaagcttg ttttccttta taattctttt caggaattat
645901 accttacttc aatttagaag cgcatagcaa acgggaagaa tgcgtacact gcagggttgt
645961 tgtgatccgt cacgtgtatg caaaacgcgt tagagagtag ttatgtgcta actgtgtggt
646021 agaaatttat atttctcttt taaggttgtt tggtatgtat ccgccgtgaa aaaagtaaga
646081 aaacatccaa atgggctcct gcctgaatgt ttccttcgat aaacgtatac gccaatagtg
646141 aagaaagtcg cctaaattta ttctgttgta acgaatgatt catggtttaa cttttttaga
646201 ctctagtata actagcaagt atacatattt gctcaaaaca tgttcgagtg cgaaagtgtt
646261 gacatataaa gagacacttc ttttacgttc cactgtttcg agtttacgtt gaagatttgt
646321 tttagggtgc ttaatcaaag aacaacaaat aaaaaatgcc tgtggctgct cgatatatat
646381 ttttgaccgg cctatttttg ctatctgtag ctaatgttgc tctaggtact acagaggctt
646441 gtttgccagc tggagagaag aaaaatggta tgactataaa cttttaccaa tattccttaa
646501 aagattcatc tacatactca aatccgtcat atatggccta tggttatgct gatgcagaaa
646561 aactgggttc tgtaagtggg caaacaaagc tttccatcga ttattccatc ccatgtaatg
646621 gcgcatcaga tacttgtgct tgttccgatg atgatgctac tgaatatagc gcttcccagg
646681 ttgtaccagt gaagcgtggc gttaaacttt gttctgataa tacaactctt tcttctaaaa
646741 ctgagaaacg tgaaaatgac gattgcgatc aaggcgctgc ctactggagt tcagatctgt
646801 tcggattcta cacaacaccc accaacgtaa ccgtggaaat gacaggttac tttttaccac
646861 caaaaactgg tacctacaca tttggcttcg ctactgtgga tgattcagca attttatcgg
646921 ttggaggtaa tgttgccttt gaatgttgta aacaggaaca gcctcctatc acatcaacgg
646981 atttcactat taacggtatt aaaccatgga acgcagatgc acctaccgac ataaaggggt
647041 caacgtacat gtacgccggt tactattacc cgatcaaaat tgtttattca aatgctgtat
647101 cctggggtac gcttcctgtt agtgtggtat tgccagatgg tactgaggtt aatgatgatt
647161 ttgaaggata tgttttttct tttgacgata atgctactca agctcactgt tccgttccaa
647221 accctgctga gcatgcaaga acttgtgtat catctgcaac atcttcctgg tcgtccagtg
647281 aagtctgtac agagtgtacc gagaccgagt ctaccagtta tgtgacacca tatgtcacta
647341 gctcttcctg gtcgtccagt gaagtctgta cagagtgcac cgagaccgag tctactagca
647401 cctctactcc atatgtcacc agctcttcct cgtcgtccag tgaagtctgt acggagtgca
647461 ccgaaactga gtctaccagt tatgtgacac catatgtcag ctcgtctact gctgccgcaa
647521 actacactag ctcattctca tcgtccagtg aagtctgtac agagtgcacc gaaactgagt
647581 ctactagcac ctctactcca tatgtcacta gctcttcctg gtcgtccagt gaagtctgta
647641 cagagtgcac cgagaccgag tctaccagtt atgtgacacc atatgtcagc tcgtctactg
647701 ctgccgcaaa ctacactagc tcattctcat cgtccagtga agtctgtaca gagtgcaccg
647761 aaactgagtc tactagcacc tctactccat atgtcactag ctcttcctcg tcgtccagtg
647821 aagtctgtac agagtgcacc gagaccgagt ctaccagtta tgtgacacca tatgtcagct
647881 cgtctactgc tgccgcaaac tacactagct ctttctcatc gtccagtgaa gtctgtacag
647941 agtgcaccga aaccgagtct actagcacct ctactccata tgtcaccagc tcttcctggt
648001 cgtccagtga agtctgtaca gagtgcaccg agaccgagtc taccagttat gtgacaccat
648061 atgtcagctc gtctactgct gccgcaaact acactagctc attctcatcg tccagtgaag
648121 tctgtacaga gtgcaccgaa accgagtcta caagcacatc cactccatat gcaacctcat
648181 ctactggcac agctacttca tttaccgctt caacttccaa taccatgacg tctttggtcc
648241 aaacagacac aaccgtttct ttcagcctat cttcaactgt aagcgagcat accaacgctc
648301 caacttcatc tgtagagtca aatgctagta ctttcatatc gtcaaataaa ggcagcgtta
648361 aaagttatgt tacgtcatcc atacatagca ttacgcccat gtatcctagt aaccaaaccg
648421 taacatctag ctctgttgtc tccacaccaa ttacttccga atcttctgaa tcctcggcct
648481 cagttaccat tctaccctca actatcactt ctgaattcaa accatctaca atgaaaacga
648541 aggtcgttag tatctcctca tcaccaacta atttgattac cagctatgac actacatcta
648601 aggattcaac tgttggttca tccacatcgt ctgtaagcct gatctctagt atttctctac
648661 caagtagtta ttcagcttct agcgaacaaa tatttcacag ctccatcgtt agttcaaacg
648721 gtcaagcatt aacaagtttt tcttcgacca aagtcagttc ctcagaatct tctgaatcac
648781 atagaacatc gcccactaca tccagtgaat caggcatcaa atcttcaggc gttgaaatcg
648841 aatctacaag tacctcttct ttcagctttc acgaaacttc tacagcctcc acctccgttc
648901 aaatatcttc tcagtttgtg actccatcct cccctatttc cacagttgcc cctcgttcta
648961 cagggctcaa tagtcaaact gaaagtacaa attcttccaa ggaaaccatg tcgtctgaaa
649021 atagcgccag cgttatgcct tcttcatcag ctacatctcc caaaacaggc aaagttacca
649081 gtgatgaaac ttcttccgga ttttctcgtg atcgcaccac tgtgtatagg atgacttcag
649141 aaacaccctc cacaaatgaa caaacaactt tgattactgt aagttcttgt gaatcaaata
649201 gctgctcaaa cacagtctca agtgctgtag tttccacggc caccactacc atcaatggga
649261 ttaccactga atatactaca tggtgccctc tttctgctac ggaattaaca acggtaagta
649321 aattagagtc agaagaaaaa accaccctaa ttacggttac ttcttgtgag tctggtgtct
649381 gttccgaaac tgcttcacct gctatcgttt cgacagccac tgctaccgtc aatgatgtcg
649441 ttacagttta ttccacatgg agcccacagg ctacaaataa actagcggtt agttctgaca
649501 tcgaaaatag tgccagtaag gcttcattcg tttcagaggc tgctgagaca aaatccataa
649561 gcagaaacaa caattttgtt ccaacttctg ggactacttc tattgaaaca catacaacca
649621 ctacaagcaa cgcgtctgaa aatagcgaca atgtttctgc ttctgaggct gtcagtagca
649681 aaagtgtcac aaatcccgtg ttgattagtg tatctcaaca gcctcgtggc acaccagcaa
649741 gtagtatgat aggatctagt acagcctctt tagagatgtc aagctacctc ggcattgcaa
649801 atcatctact aaccaatagt ggtattagta ttttcattgc ctccctatta ctggcaatcg
649861 tttaataggt gcagaaatat cctttggatt gatacttctg cgtctacgat tcgtcctagt
649921 gccatattat gtacctattt atttactatt catttctttg ttcttctact tcaaatagct
649981 cagaatgtat tattttttta ttaaaatcat ttctatatat aggattaacg agaaaccatt
650041 ccgggagtgg catctctatg ttttctctat gtaagccaca ccagagaacg ttgctgtact
650101 aagacaccca tttcgagtat agaagcttat tgaaaatgaa ctgatatttt ttaatacata
650161 taaatctcga ttaaagacaa agcttattgg acatggagta gatgttttga tcaatagatt
650221 ttcaacaaat tgaacggttt gctttagata ccgtttgaga taaaatactg cattttaatg
650281 aaacataaag tcaaccaaca gctgaagctt aacaatagtt actactgccc ggcgttatta
650341 tcacaacaat tcgttctacc aaaaaactgt gatctttact aaaagacctt ttttttttca
650401 gacaattttg cttaacgcag taaaatgtag taaagacgaa ctttcggata aaagactcca
650461 aagatagtat gataaacaga cagtggtatc agtactatag acaccagtta agacgttggc
650521 actgtcttca aatcttggct agaaattttg gagggtatca gtcaattgct gtctgcgcat
650581 cccaataaac agttgtctag gaaagaacaa cggttttaat tgacacaaca tgctgaagaa
650641 tataggaaaa ggagtagcgg caacggatga gctagcaaga aaagcatcac tctctatctg
650701 aaagcttcca tgatttatct ttcaacccag caaggtagtg tttttccaat ataagaagca
650761 tacggggtta tagaagctaa tcgtgcccag catgagtcct aacaaacaga acagactctt
650821 tatccatccg aattctagta agtaattatt ctgttcactt ctatccaacg aaatgggcgt
650881 acgattgaaa taacagttga ttgaaattat aggggcccta ttcgccttct acaaagcaca
650941 aggaaaggaa catttacaat gaataatacg aaacagctgg caaatgtgct gaaaaccatt
651001 gagcgatgtt accacgctga gatccatgtt ttcaagagtg ggctgtacta taatgaacca
651061 atgtgttctt taaaattgtt agtgtgtttt cccaacatga aattgctact ggaagaaatt
651121 gatattgtaa taatatatgt gagtatctaa tcacacactg gctgcatcac attgattcat
651181 gttatgtttt tgaaattaat gtattcgttg tgcatggatg ttacacatat cctaaaccta
651241 aattatgagt acaaacacac ctaggtagag agctctacgt cgtcttagtt ctcagcttgt
651301 aagctttaat ttacgcgaaa agctatttac aattttttat ttgaaaattg atcgcataac
651361 ttaatgaaag tgtacaaagt aggataggca ttctttggta ccgattttct gaattgtcac
651421 cagcaaagcc tcatttattt gaaatcatga aacttgttaa cgattaaatc tagcatggcg
651481 atactcggaa agtccataaa gaacttctgg caagagccga aattcacggt aattttaatt
651541 gagcaccact atagcagtgt ctttattgag ttggctaaca ctaaggtcgt attcagtact
651601 tctgaatttc cagataatat aatagacgct catactaaga aaatattcac tataagaacc
651661 tttcacaaat actaacctag aatatttatc tttctatttg agtaagaatg gaaaataaaa
651721 aagtgttaat aaggtataac agagtgtatt ttcaaccgta aagaaatgaa taagaataaa
651781 cgcgatttaa gcttaataga aagtacataa gcaacgtcgc gaaccggtaa tggaaaaaat
651841 aattgtttta tcgcttttct tcagagggtt tttgtaatcg atatttgggt ggaaaattct
651901 ggggccctac gaaatgacga actaaaagcc aagagttcta aaacccttca gtgtagtgct
651961 ttttgaaaag ccagttttgt tatgagcaac aaatacatgt gagcttagaa agatagattg
652021 agcttacctg aatcaatgtg aatcgaaaat ttcctccgtc ctacaagtat atattggagg
652081 aagataaaac caagattgat gcactgcgtt ttgtaaatag gttctgggat taccaacgta
652141 cttcttgata aaatgggcta tttttaaacg ctttactttt tttcttcagc ggaacccggt
652201 ggtttttatg atctttatac ttaattgatg attacagttt tggaatcaaa agctttattc
652261 ggaatattgt gcaaatatat tgttgttttt attggataat ggtgtctaga tttaaccaag
652321 atattagatt tatttcgctt atagcatcat tttttttttg atcaaaattt tcaactcttt
652381 gaaagtgcca tatttcacaa aatataacat ttgtcccacg atttagaaaa ataccataat
652441 cactcttcaa caattttatt tctttactct cctactacag ttgcgtacat tttaactaca
652501 cgtttaaaat attcaagatt tatgagactg tcatcgaatg gtatataaaa taaaaaaaaa
652561 ttatatctta gagtcctagt ttaatagaaa gaataaaaaa ggtcacggaa catcactttc
652621 taacatatct tcctgggttt catctttact agaactgacg gtcaaaggtc tttggagagt
652681 actcgctttt ttgatgaaaa tcacgatagt taatttttcc gccatgttgt aactttctca
652741 aaactgcaat ttcagggtgt ccaatttact gtcaatatgc aaccaaaaat ataacaaagt
652801 ccttttgagc aaataaagtc ggacatgaca gtacaacgca tgatcgatta ttaaacgaaa
652861 atgggatatc atactgtttt agaagttatt gggtgcatta ctctgtcata aaaaaatcat
652921 gttactatct ataaaaaatg cctaaaaaat tggattacca cttgttatgg aaagatcagt
652981 aaaatatagg ataaccatag cgtaagtctg gcgttctgga atatttgttt tttagttatt
653041 aaacatactt ttcacgattc acagtattaa tttttaggaa tgataaaaaa tggtacatgc
653101 ccctattggg aacgtgatga tctttcggaa tgtgctaggc gagaatatat cgagtttaaa
653161 tttcctctat ttatattgtt gactggtatg atatacgcgt tttgcaaagt ctttcgagcc
653221 ttttatctaa gggggaaaaa tcatacaaat gaagcgccag aatttgaaga acaaggtaat
653281 ggaaaccacg aatatgcaag gttctcagtt ttaagactaa aatctgcatg ggaaagccgt
653341 agcttttgta atgttaataa tagatctact ttcgacaaat tcaaaaaatt tatagagggt
653401 gccttcattg ttttgcagct tactatccac ctgtatattt tatctagtat gccaatggat
653461 aacaaaaagt tctttcacca aggttttctg gttcaaatgt ttctctggat tttactgctt
653521 gttgttatta cacttcgttt aatttcagca agccagtcat ttcggtgggt tttagcatgt
653581 aagcgtgatt tatgggctgt ttcgttttac tcatatgcat ccctgtttac tctttcgatt
653641 ttacctcttc gttccgtctt cattggaaag ataaaagata aaattatggt caaatatatc
653701 atttccgaga ctttcattga tttagcgctt ttattattat tatcaacgtc aagtatagaa
653761 ggaactaggt actcattttt ggttgaaaat gagaacaaaa agttgccacc ggctcctacc
653821 gtctttggcc ttcttacttt ttctaggatt gatcggctta tttggaaagc atacaaacac
653881 tgccttggaa acgctgatat ttgggatttg gatattaata ataagtctat agcaattttg
653941 gcgaactttg aaatgtcttc taaaaaagga aggctccttc caaacattat ttgttatttt
654001 aaggctgttt tcatctccca attatttctg gcttttgtat ctagtttttt gaactttgta
654061 ccctcattgt tgatgccaag aatactatca tacgttaatg acccaaagtc aaaatcatgg
654121 aacttggtgt ctttatacgt ctcatctatg ctcgtcagta aaatcattgc cacgacttgt
654181 agaggtcaag gattgttttt aggtgaaaag ggtactatgc aactaagaac agttttgata
654241 tccaatatct attccaaaac cttaagaaga acaattctaa aagactcaac aacgtcactt
654301 caaaaaaatg cgtcaacatc ctttgaagaa aatcctgact cttctgaagc ggaacctaga
654361 aaaaagtcta gtaggaaaga caactctgtg aacaatgtta tgtcaattga cgctttcaag
654421 gtttctgaag ctatgaacac tttttatctg gcatgtgaag cagttttcat gacagttacg
654481 gccctaatga tactatattc cctactggga tggtccgcct ttgctggtac ctttgctctt
654541 cttgccatga ttcctttgaa tttttggtgt gcaacttttt acgggaacta tcaggccgat
654601 caattaatcc taactgacaa gcgtacctct gggattagtg aggctctgaa ctcaatacgt
654661 gtaataaagc tactggcatg ggaaaatctg ttttatcaaa agattataaa cgtaagagat
654721 ggggaaataa gactccttaa aaagaaggca acaattttct ttttgaacca tctcatttgg
654781 ttctttgggc ccactttggt ctctgcaata acattctcag tgtttattaa attccaaaat
654841 cagacactta ctcctacaat agcatttaca gctctttctt tatttgcaat attgaggaca
654901 cccatggacc aaattgcttc gactgtcagc cttttgatac agtcttttat ttctcttgaa
654961 agaatccagg attatcttaa tgaatcagaa acaagaaaat atgagatttt ggaacaaagc
655021 aatactaaat ttggctttga agatgcaagc atggaatggg aagctgctga aacaagtttt
655081 aaacttaaga acatttctat tgattttaag ctgaatagtc tcaacgcaat tataggtccg
655141 actgggtcag gaaagtcttc gctattactt ggactattgg gagaattgaa ccttctttct
655201 ggaaaaatat acgtacctac agttgaatcc cgcgacgact tagagattgg taaagacgga
655261 atgacgaatt caatggcata ttgttctcaa actccgtggt tgattagtgg aacaattaaa
655321 gataacgttg tttttggaga aatcttcaac aaacaaaaat ttgatgatgt aatgaaatcc
655381 tgttgtcttg acaaagatat caaagcaatg acagctggca taagaacaga cgtgggtgat
655441 ggaggatttt ccttatctgg cggacagcag caaaggattg ctttagccag agcaatttac
655501 tcctcttcca ggtatttgat ccttgatgat tgcttgagtg cagtagatcc tgaaactgca
655561 ctttatatat atgaagagtg tttatgcggc cccatgatga aaggaaggac ctgcatcatt
655621 acgagtcata atatttcttt agttacgaaa cgggctgact ggcttgtgat tttagatcgt
655681 ggcgaggtga aatcacaggg taaaccatcg gacctcatta aatctaatga gtttttgagg
655741 gaaagcataa acaatgattc aaaaaataca actcacaatc aaattgactt gaaaagatca
655801 acaacatcaa agaaaactaa gaatggagat cccgagggag ggaactcgca agacgaagtg
655861 tgtgctgaag ttgaaaattt tgaggaaaca aaaatggaag gatcagttaa attttcagct
655921 tacaaatggt tagcagacta tttcggggga ctgggagttg tttttgtttt cacctcgtcc
655981 tccatcctta ttcatggaat cacactgtct cagggctttt ggctcagata ctggctggac
656041 actggatctt cagggagtaa gtctacctgg ctttatagaa tagttgaggg tcactctaac
656101 atctatttct tactgactta tattatcata ggtcttgttt cttcattttt aacttctggt
656161 aaagtttgga tagcaataat ttcaggtacc aacgtcacca agaaaatatt tgcgaagctt
656221 ctatccagta tcttatatgc caagttacgt tttcataatg tcacgccgac tggaagaata
656281 atgaacagat ttagcaagga tatggatatt attgatcaac aattgatccc taatttcgaa
656341 ggactctctt atagcgtcgt tgtttgtctg tggattatac ttttaattgg atatgttact
656401 cctcaatttc tgttatttgc tattccttta tgcgctcttt attataccgt atgtacgtta
656461 tatcttcgtg catctagaga gttgaagaga atagataaca tcaatatctc tccaatacac
656521 cagttattcg ctgaagccat caaaggagta actacaatta gagcattagc agatgagcgt
656581 aggtttatca ctcaatcttt ggttgcaatt gacagaagta atgctccatt tttttatctc
656641 aatatggcca ccgagtggat cacatataga gtggatataa ttgggacact tgttcttttt
656701 agttcttctg taatgatcat aatgaaggcc tcatagttgg atgcggggct agcggggata
656761 ctgttatcga atgccttttc ctttactgaa actgctcaat ggatcataaa agtattttca
656821 agcgttgaac ttttgatgag ttcagtagag agaataaaag aatatacaga tataccttcc
656881 gaatcaaacg gctacatatc acctccagct aattggcctc aaacaggaga tgttgaacta
656941 aaaaacttat cattgcgcta ttctcctcat tcctctaagg cactagataa tgtatcattc
657001 aaggtaaaag caggaacaaa agttggtatt gttggtagaa caggggctgg gaaatcttct
657061 attatagcgg ctatttaccg gctttcagac tgggaaaacg gtacgattac tattgataac
657121 aaagacataa aacatatccc tttagagcgt ttaagaaatt ctataagctg catcccacag
657181 gatcctactt tatttgatgg aactgttcga tctaatttag atcctttcga tcggtattct
657241 gatgtacaaa tttatggcgt actatccaaa gtgggattaa ttgaagaatg cgatgaattg
657301 tgcttgattt ttgagcaaga gcagcctaat ttttctagtc ataaactaag aaatagattc
657361 attgatttga atactgttgt gaaatcaggt ggttcaaact tatctcaagg gcaaagacaa
657421 cttttgtgct tggcacgatc catgcttggt gcacgtaata taatgctaat tgacgaagca
657481 accgcctcaa tagattatat ttctgatgct aaaattcaga aaactataag agaaacaatg
657541 aaaaatacaa caattttgac tattgctcat cgattaaggt cagtaataga ttatgacaaa
657601 attctggtga tggaaatggg cagagtcaag gagtatgatc atccatacac tctaatatct
657661 gatcgaaata ccatttttta ccgcctctgt aggcagagtg gcgagttcga aaaccttttc
657721 gagttggcta aagtctcatt cgataataaa agataagaca actagaattt cctattttta
657781 ttcattccag ttctagctac gaagtatacg atctgcttac gtcatatatt tgtgtgtaat
657841 tagaaggcat tcaggaagtc gcttttaact tttcagggct atatgtccta atccactact
657901 ttttttgaga actttaagaa ataactcctt tgaacctgtc tgtgccaaac aaaattttgc
657961 tggtacattt tatggtatat aaacaagcta cgttattatt actttttttt gatagtttta
658021 cttatactag aaaataatat tatatcatca caaaagaaac tctctcgtta agaatcccga
658081 atattcagca ggagcaaaaa aaaaatacca taatttaaat gcttattcag tacttagctg
658141 ctgattttat cgcaagtata ctattggaga gtaccgtggt tcatatcgtg ctatttttat
658201 ctatatttaa atttatagaa gtttatcgta gtatactatg taattctctg ccgtattggc
658261 ggcaaagaca aaagcactga cagtaaacag tttttctgat gagaatttat gtcgaggaac
658321 aaacgaaaat tttgctggcc aaatttgctt acgcctttaa tgtgattgcg gttgaggtct
658381 gttattacgc agctgctatc atgtgtctat ttgagattct ctttacaggt tatcgctgca
658441 tttttgtcaa gaaaagaaaa gaagacaacc tttttcttgc actgcgatga gtatattcag
658501 gctcgcgaat tttccagatt tcttactaaa gacacatctt tgaacgcacc agcatgaatt
658561 ttatgaacta ctgatccata tattaatagg ttttaagtac atatagaata cttaagaaat
658621 tacattccat tgcgatacac ctatttgatt ctgattgtgt tgaagtctgt ataaaaggcg
658681 aaaaaaaata aaatgaaaat aagaaaataa ctgcgctact tgtcttctaa attatcttct
658741 ggtgtatcgt ccttttttgg tatgattaat ttcttattgg atgaaaaact acaaaacaaa
658801 aatcctaagg cataaaaccc tagatccatc caaaatacgt tcttaatgga gtcgcttaaa
658861 atgtttccaa tagtcgaatg agaaccgtcg tagttttgaa gacgatacaa aatcatgtca
658921 tcaaccgttt ttccttcgta aggctctaga tgagctcgtg atactttatt gtgaaaggag
658981 gcggaaaaaa cagtggttga aagcacacca ccaagagttg tacctaatga cttcatgaat
659041 gtattgaaag ctgttacttc aataaagtcc atagcagctt ctggacgatc tttggtaatt
659101 tgaagctgtg cactcatgag cgatgcttgt agagcaaatc caagggaaaa ccccggtaat
659161 agcaaaacac caatttgagt tgacttcgtg gacgtatttg tcataagtgt cataagccct
659221 gctccaatta ccccaagaac gcctccaaat attaagagtg gtttaactaa accgagcttt
659281 ttggtaatca caccacttgc aatggccgca ataacgttgg taataacgat tggtatcaag
659341 tgaagaccgg ctttccatgc actcgacgca aatataagtt ggaaaaactg gacagagtat
659401 atcatttgcc cattgtaacc ggtacataat agaaatgtta ccatgtttac tattattatg
659461 gctggttttg ctaccaatct tcttagaagg agaggcctgt aggatatatt atcaggttcc
659521 gggttgaatt tatcgaatag gaagaaatcg tacaccaatg aaaaaataaa aagtaagaca
659581 cccaaaacca aatatgtgat gacttggcca gagttccaac tatatttatt accaccaaag
659641 gttagcccca gtaggaaaag gaccagccct gcagagcaga gggcaaaacc aaagaagtca
659701 aacttgaaga ttatgccatt cataagtctt ttaaaattaa cttggtgtct gaacttacta
659761 aaagtaaagc tcgagattgt tcctatagca tctttaattt gttgaagtat acccttattc
659821 tcggccttat aggtgagtaa aaacataata atggcaagac caccgatagg aagattgata
659881 tagaagcacc acctccaggt aacatgggtt gtaaaggcac ctccgattat aggaccaacg
659941 atagcagcta cagcaaatgc acaacttagg atggaaatca ccaatggacg tgacctttca
660001 ccaaccatcg tacaaccaat aacaaagcaa agcgtttgga gtccgcttcc cccaacacca
660061 gcaacaactc taccgaaaat gagcatattc attgaagagg caagggcagc aattagggat
660121 ccggcttcaa aaataagtat tgctaaaatg agactatgct ggaaacctat gatagatgcg
660181 aatcttcccc aaatgagact cagaatagca tttggtaaac tgtagcctgt aacgagccaa
660241 cctgttttgg agtagtttcc gaactgttct gcgaccacgt caataatagt tcccactatc
660301 aaaatatcca gtgcagttat gaatagtaca agagttaacg aagccaggca gaggtacaag
660361 gaaagtccca ttggagaatc attgctacct ctagcattca atgaagcgtc tgaaccacat
660421 gctccttcta tctcctgctg cgaagagtac ttagtttcct ccatattttt gaatttctat
660481 cgattaagct ctataccagg tatgatctgg tctgatcagt tctaggtatg agtataacta
660541 gaatacatct atatatatgt atatatatat ttaaaccaaa aaaaaaaaaa attcgcttct
660601 cataaaggtg tgatgacact attatctttt gcatattttg tcgactcgta tcatgtacgc
660661 gctgcatatg aggtgcggcg ctatctgtta aatatgtact aatttgcacc tgctgcaaag
660721 gaaatgtggc actactttta ctcgcatgtt aactttcacc tactatatat agaaaaaagg
660781 gtgttgcttt caatcgccga ctaatttgct caaatactct ttacacaaag gaaattgtgt
660841 atcagtaacc cttacggttt gtttatgaag gaactttgct cgtcctacac caccggatct
660901 aggtactcaa ttttttgatg attttgcact tgtgctcata tcctgtcgac aggcaccgca
660961 tttttttcct tgtttcaaca gacataaaca caagcttcac tcattagttt gaaaagagat
661021 agtttcgacg gtacagtatt cttgtcgtac aaaagtcttc ggtataactg gttcgttgtg
661081 gattttcgga aagtaagttg attgtacgac gacaggtcaa agttaaagtt aaagtcacca
661141 ggtgtataga caccacattg aaggggcgtc acagcaattt tttttatttt tttttgatac
661201 tcaataatta cgagcatata attttagtac ttccaaaaaa aagttaaaaa aaaaatagtg
661261 acaaaatgtg tcagtaaaat atatatgaga acatggaatg tattaaagta attccatttc
661321 tagcagatgt agcgaccgta gaatcttaaa tactatttac ataaataaga aaagtaaaat
661381 agttttatgg actggaacga gaaaaaaaaa aaaaagaata atcaagtaaa taaattatcg
661441 gatgagttct agtgttgttg gtgcctcaag taataaaaaa agtggaatta ggcagtcctg
661501 tgagattatt gagcgagaac gtcactcaaa cgatgacacg tactctatga catcgacctt
661561 ttttaagctc aaagaaaacg aaattatgtc tgcacagttt gattccttga aatataaaat
661621 tctactgata agtaccgcgt ttgtatgtgg gtttggaatt agtttagact acacacttag
661681 atcgacctat acgggctatg caacgaactc atattcagaa cactccttac tttcaactgt
661741 ccaagttatc aatgctgttg tgagtgtcgg atcccaagtt gtctactcta gactctctga
661801 ccacttcgga agactaaggc tttttttagt tgcaactatt ttttatataa tgggaaccat
661861 cattcaatca caggcgaccc gtctcaccat gtatgcagca ggatcggttt tctataactg
661921 tggatacgtc ggaacaaatc tgctcctgac attaatactc tcagatttct cctccttgaa
661981 atggagaatg ttttaccagt acgcctcata ttggccatat atcataatac catggatttc
662041 aggcaatatt atcacagcag caaatcctca gaaaaactgg tcctggaata ttgcaatgtg
662101 ggcttttatt tacccactct ctaccttgcc aattatattt cttattcttt atatgaagta
662161 caaatcttca aagactgctg agtggagatc tctcaaagaa caggctagaa aggaaagaac
662221 gggcggatta tttgagaatt tggtgtttct attctggaaa ctcgatattg ttggcatatt
662281 attaataact gtgtcgctag ggtgtattct tgttcctttg acgttggcta atgagacatc
662341 acaaaagtgg cacaattcaa aaataattgc cactttagtt tcaggtggct gtttattttt
662401 cattttttta tattgggagg ccaaatttgc caaatctcct cttctaccgt tcaaattact
662461 aagtgatcgt ggaatttggg caccccttgg tgttactttt ttcaattttt tcaccttttt
662521 catttcgtgc gactatctgt atcctgtttt gctggtatcg atgaaagaat cgtccacttc
662581 ggctgctcgg atagtaaacc ttcctgactt tgttgctgct actgcatctc cattctacag
662641 tttgttggtg gcaaagacaa ggaaactgaa actttctgta atcggaggtt gtgctgcatg
662701 gatggtgtgc atgggccttt tttacaaata cagaggagga tctgggtctc atgaaggtgt
662761 tatcgctgca tctgttatca tgggtttgag cggtctccta tgcagcaatt cagtgatcgt
662821 catactgcaa gccatgacta cgcatagtag gatggctgta ataaccggca ttcagtatac
662881 cttttcaaag ctaggcgctg ctatcggtgc ctccgtttct ggtgccatat ggacacaaac
662941 catgcctaac caactctaca agaaccttgg aaacgataca ttggcagaaa tagcatatgc
663001 atcaccttat acattcatta gtgattatcc ttggggctca ccggaaagag atgctgtggt
663061 tgaatcttac agatatgttc aacgaataat aatgacggtt ggcttggcat gtacggtacc
663121 gttctttacg tttacaatgt tcatgagaaa cccggaacta atagacaagg cgacacacga
663181 agaattcact gaagatggtt tggttgtctt gccagatgag gaaaatattt tctctcaaat
663241 caaggcactt tttagacata atcgaagtaa caagaaatca ggatgttgat ccccaagctg
663301 gtgaaaaaag ggcaaaaaaa aaatgaaagc aaaatcacaa aaaaggcaaa aacaagtgat
663361 ttctacattt ttattacttc cgataaaaat gacataacag gataggataa acatgctcga
663421 tagacccaca tttgaacttg cgacgcatat agctgtgtcg tactttttat tttcacaagc
663481 gtcggtaaaa actcagcgtc ggtaaagact cagcgtcagt aaaagagtca gcgtcattga
663541 tattaaaagt gcgggaggag ttactatcca ataaatgatg ctggaaatgc gctctgtatg
663601 aatgcattaa ttatgttgta ccgaaaaaga aagaaagaaa gaaaaaaaag aatatcatgt
663661 aacttctagt aagggcgtca tgtcatagca cttttctaag tgtatgccat tgtaaatcat
663721 tctaagcgaa aaaaagtgat atgtctcctg gtattttgta ttgttgtcgt tacaagttga
663781 tgtgttccgt agtgtgagtg caacatgcga ttttggtacc gcaaaaaagg tacagatcac
663841 atgggcacag atacaacaat tctttatgcc tgtattgaga tcatagtttt cttggagtcg
663901 gcaacagtct acgggtgaac ccaataatcc agcagtaaat ctactaaccg aacattgtgt
663961 cggaatttac acattactga tataattcgt cccattaaac ttgctgcgag tgatttccaa
664021 aacaagtact acattgagcg tgttcagcgt gcccaaaaga aatggacttg aaaatcttgt
664081 tgaattaact gtatatcctt taaattagct gccacaatga tagctacctc cgcgatatat
664141 tgacgttact aaccttttga gattcttcac caatgttgca gcgtgattta attttgatga
664201 aatcattttt gttgaaagag taggatcctg tacaggctga aatatactgt tcttcaatat
664261 atcacttatt ttaaatgata cagccatgta ttttggggat atcagagata atatcatacc
664321 cgattgagct ggaactccta ggattgttga cagatgtcga ctatggctcc ttactaacag
664381 agtatggttg tgaagctaat acagataatg tctcactcgt gcagtcacat ctccattgaa
664441 agctgtggag tttttccaga caccagtagc agcgccaatg gcagcactac agcgaaagtt
664501 gaactcatag cacatccctg aatcgtggac agttaatgta tgttgttgtg actcagacga
664561 taacgataag cctcaaaaag ttgtgtcctc tcatcatcct cgagcaccag tatatcataa
664621 gcaaagaatc ttcgataatg atttggaaaa aaagcgaaag cgaagccaat gtgttttatt
664681 actgctgcat tactgaagag atataagaag cgctaactca attacaagag cacataacgg
664741 aattaatcct gcgaaacaga acagtaattg acacccttat agtagccttt tttaacagtt
664801 aattatggaa aactgagttt gaaattcaat gttaacgcaa gtttctgtta tttttgcgaa
664861 tctagacggt ctcaacgaga cgatatgctc taagattcta cttctctgcg gatgattctt
664921 tcggttatcg atgcccttta ccaaggcctc tcataccata gtatcagaag agcaatgcat
664981 attcattcat agatataatg tgatatggag agcaataatt aaatttatgc gagaaaaatg
665041 tgttcaatat aagaatattg aaaaaaatat taaaatgaaa attgaaaaag gcctctttga
665101 tacacacaaa taatgccatc tcttccagta aaagataagt aagataaact ggctatgtta
665161 tgctgtctgt ttatatgttg atacaaggaa ttaagatcta tcttatatgc cttagcgtag
665221 cgcaagaatt gaacatttct atataaaata agtataagac acgtagggtt actacttctc
665281 tgtgtgcata tacctgtgtt acggtattgc atgcgagatg gggctagacg agaccgtagg
665341 gacatatagc accttagaaa taaccttgta tgaaatcttt cattatttcc tgtttagaca
665401 cttgcgtcaa ggtatttttt ttatcgtggt gttgaatgtg gtaacccaat agcataatat
665461 gagtaatgct ttagtattgt ttcagagctg ttttagataa agaaaacata tagtagcaaa
665521 cctctaatcc ggtagtactt aagaaactat agtttctatg tacaaaacgg taactatgta
665581 attcttacat ttacataaca tgtagaagaa tccaataaac ttactacaat atgacatata
665641 agctagatcg taattcatta cgtcaacata ccgtaaaatt atttggcgtt tcgttaactc
665701 ctacaaaaac aacaaaccta tcaccgtatc gtcttcttta gatatagtct cttcgtatga
665761 gtagtgtcac atacaagatt aaagatgcat tagttatgct tttaggatat tgcggttagc
665821 atatgggaat agaaatagga tgccattgta tcatagcacc tgcatgagtg cgagccacta
665881 ccatattgtt tctcggtgaa taaagagtgt gtttatgtat tattgtcgaa agatagaata
665941 tttttatgtt taggtgattt tggtggtgat tttttggtta tattaacata agtgtatata
666001 aattgagtgg ttagtatatg gtgtaaaagt ggtataacgt atgtattaag agcatttata
666061 cgatatttgg gcccgccgaa tgagatatag atattaaaat gtggataatc gtgggaatta
666121 tgcgtaaatg gcacagggta tagaccgctg aggcaagtgc cgtgcataat gatgtgggtg
666181 catttggtac tgatttaatg agaatgggcc atggattgga gtgtgagagt agggtaagtt
666241 tgagagtggt atatactgta gcatccgtgt gcgtatgacc gatcagaata caagtgagga
666301 tggctatggc atgtggtagt gggattagag tggtagggta agtatgtatg tattatttac
666361 gatcatttgt taacgtttca tatggtgggt agaacaacag tatggtgagt aacagatggc
666421 tgatggtagg gtaatggcag ggtaagtggt ggagttggat atgggtaatt ggagggtaac
666481 ggttatgatg gatggtggtt gggattggta gggttgaatg gcacagggta acgaatgatg
666541 agttgggtaa tggaggtgta agttgtgaga caggttcatc agggttggag tagggtagtg
666601 ttagggttgt gggtgtgtgg gtgtggtgtg ggtgtggtgt gggtgtgggt gtggtgtggg
666661 tgtggtgtgg gtgtggtgtg ggtgtgtggg tgtggtgtgt gggtgtgtgg tgtgtgggtg
666721 tgtgtgggtg tggtgtgtgt gggtgtggtg tgtgtgggtg tggtgtgtgt gtgtgtgggt
666781 gtggtgtgtg tgtgggtgtg ggtgtggtgt gtgtgt
//