LOCUS       BK006944              666816 bp    DNA     linear   PLN 29-JUN-2021
DEFINITION  TPA_inf: Saccharomyces cerevisiae S288C chromosome XI, complete
            sequence.
ACCESSION   BK006944
VERSION     BK006944.2
DBLINK      BioProject: PRJNA43747
KEYWORDS    Third Party Data; TPA; TPA:inferential.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 666816)
  AUTHORS   Dujon,B., Alexandraki,D., Andre,B., Ansorge,W., Baladron,V.,
            Ballesta,J.P., Banrevi,A., Bolle,P.A., Bolotin-Fukuhara,M.,
            Bossier,P. et al.
  TITLE     Complete DNA sequence of yeast chromosome XI
  JOURNAL   Nature 369 (6479), 371-378 (1994)
   PUBMED   8196765
REFERENCE   2  (bases 1 to 666816)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   3  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
REFERENCE   4  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   5  (bases 1 to 666816)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
COMMENT     On Apr 18, 2011 this sequence version replaced BK006944.1.
            Chromosome XI sequence was verified by resequencing.  The sequence
            was mapped to the previous GenBank records except for a 500 bp
            region.  That region was determined by sequencing a descendant of
            the S288C strain, AB972, and is present in GenBank as JF740677.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-3-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
PRIMARY     TPA_SPAN            PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1809              Z28225.1           1-1810
            799-2388            Z28224.1           1-1590
            2182-3502           Z28223.1           1-1321
            2722-6106           Z28222.1           1-3385
            5621-9090           Z28221.1           1-3470
            7529-14484          Z28220.1           1-6955
            11227-17358         Z28219.1           1-6131
            15709-22233         Z28218.1           1-6525
            18340-25214         Z28217.1           1-6876
            24085-26826         Z28216.1           1-2743
            26160-31081         Z28215.1           1-4922
            30688-31959         Z28214.1           1-1272
            31694-34542         Z28213.1           1-2849
            34108-36698         Z28212.1           1-2591
            36415-39162         Z28211.1           1-2748
            38154-42422         Z28210.1           1-4269
            42238-47156         Z28209.1           1-4919
            46296-48106         Z28208.1           1-1811
            47973-49005         Z28207.1           1-1032
            48891-50050         Z28206.1           1-1160
            49810-53703         Z28205.1           1-3894
            53354-55934         Z28204.1           1-2581
            55603-63820         Z28203.1           1-8215
            63360-65913         Z28201.1           1-2554
            65550-68271         Z28200.1           1-2723
            67107-70733         Z28198.1           1-3629
            70221-74931         Z28197.1           1-4713
            73866-75748         Z28196.1           1-1883
            75535-77257         Z28195.1           1-1723
            77033-78865         Z28194.1           1-1833
            78647-80159         Z28193.1           1-1513
            79883-81034         Z28192.1           1-1152
            80538-82946         Z28191.1           1-2409
            82640-84703         Z28190.1           1-2064
            83075-86224         Z28189.1           1-3150
            85904-89283         Z28188.1           1-3380
            88787-92743         Z28187.1           1-3957
            91537-94498         Z28186.1           1-2962
            93299-96756         Z28185.1           1-3458
            96266-98720         Z28184.1           1-2455
            98158-100670        Z28183.1           1-2513
            99642-107315        Z28182.1           1-7674
            106827-109268       Z28181.1           1-2442
            108600-110463       Z28180.1           1-1864
            109884-113214       Z28179.1           1-3331
            112504-115499       Z28177.1           1-2996
            114695-118792       Z28176.1           1-4098
            117987-120379       Z28175.1           1-2393
            120305-122516       Z28174.1           1-2212
            122237-125758       Z28173.1           1-3522
            125544-127474       Z28172.1           1-1931
            127043-130633       Z28171.1           1-3591
            130262-131287       Z28169.1           1-1026
            131069-133720       Z28168.1           1-2652
            133493-134508       Z28167.1           1-1016
            134135-137931       Z28166.1           1-3797
            135706-141793       Z28165.1           1-6088
            140692-144400       Z28164.1           1-3709
            142820-147629       Z28163.1           1-4810
            145379-149385       Z28162.1           1-4007
            148839-153268       Z28161.1           1-4430
            150688-153815       Z28160.1           1-3128
            153707-154990       Z28159.1           1-1284
            154452-155646       Z28158.1           1-1195
            155294-158612       Z28157.1           1-3320
            158181-159455       Z28156.1           1-1274
            158967-161600       Z28155.1           1-2634
            161343-163599       Z28154.1           1-2257
            162336-164916       Z28152.1           1-2581
            164386-166543       Z28151.1           1-2158
            165931-167611       Z28150.1           1-1681
            167453-169206       Z28149.1           1-1754
            168830-171550       Z28148.1           1-2721
            171130-174212       Z28146.1           1-3083
            173862-175842       Z28145.1           1-1981
            175617-176780       Z28144.1           1-1164
            176482-178514       Z28143.1           1-2033
            178173-179666       Z28142.1           1-1494
            179175-180778       Z28141.1           1-1604
            180264-182957       Z28140.1           1-2694
            182426-185285       Z28139.1           1-2860
            184545-185981       Z28138.1           1-1438
            185682-186415       Z28137.1           1-736
            186293-189123       Z28135.1           1-2831
            188641-191678       Z28134.1           1-3032
            191443-193573       Z28133.1           1-2131
            193071-195287       Z28131.1           1-2217
            195000-196348       Z28130.1           1-1349
            196029-200386       Z28129.1           1-4355
            200168-200381       Z28128.1           1-214
            200300-200800       JF740677.1         1-501
            200734-203540       Z28128.1           215-3021
            200739-200883       Z28129.1           4356-4500
            201772-205706       Z28127.1           1-3935
            205254-208246       Z28126.1           1-2993
            207750-210592       Z28125.1           1-2843
            210131-212494       Z28123.1           1-2364
            212424-214141       Z28122.1           1-1718
            212999-217343       Z28121.1           1-4345
            216701-218569       Z28120.1           1-1869
            218319-220323       Z28118.1           1-2005
            219392-221343       Z28117.1           1-1952
            220975-223351       Z28115.1           1-2377
            223286-224726       Z28114.1           1-1441
            224456-226569       Z28113.1           1-2114
            225876-228938       Z28111.1           1-3063
            228800-232226       Z28110.1           1-3427
            229881-234425       Z28109.1           1-4545
            233892-236140       Z28108.1           1-2249
            235788-237535       Z28107.1           1-1748
            237071-239184       Z28106.1           1-2114
            238892-243219       Z28105.1           1-4328
            242584-246137       Z28104.1           1-3554
            245374-248061       Z28103.1           1-2688
            247683-248919       Z28102.1           1-1237
            248368-253696       Z28101.1           1-5329
            253477-255700       Z28100.1           1-2224
            255461-256769       Z28099.1           1-1308
            256473-258502       Z28098.1           1-2030
            257844-261131       Z28097.1           1-3288
            258914-262276       Z28096.1           1-3363
            261852-263348       Z28095.1           1-1497
            263114-264788       Z28094.1           1-1675
            264291-266144       Z28093.1           1-1854
            265809-269717       Z28092.1           1-3909
            269460-271877       Z28091.1           1-2418
            270651-273393       Z28090.1           1-2743
            273210-275282       Z28089.1           1-2073
            275044-277188       Z28088.1           1-2145
            276999-278280       Z28087.1           1-1282
            277864-279122       Z28086.1           1-1259
            278665-280508       Z28085.1           1-1844
            280128-280920       Z28084.1           1-793
            280860-282890       Z28082.1           1-2031
            282330-285029       Z28081.1           1-2700
            283422-286602       Z28080.1           1-3181
            286209-288844       Z28079.1           1-2636
            288574-291452       Z28078.1           1-2879
            291053-292837       Z28077.1           1-1785
            292632-294609       Z28075.1           1-1978
            294309-296429       Z28074.1           1-2121
            296194-299581       Z28073.1           1-3388
            299076-305113       Z28072.1           1-6038
            301883-306210       Z28071.1           1-4328
            305885-307284       Z28070.1           1-1400
            306721-310198       Z28069.1           1-3478
            307828-314811       Z28068.1           1-6984
            313079-315280       Z28067.1           1-2202
            315274-316436       Z28066.1           1-1163
            315725-317763       Z28065.1           1-2039
            317058-321014       Z28064.1           1-3957
            320674-323227       Z28063.1           1-2554
            321519-325770       Z28062.1           1-4252
            325121-326407       Z28061.1           1-1287
            326113-328117       Z28060.1           1-2005
            327488-330165       Z28059.1           1-2678
            329444-330855       Z28058.1           1-1412
            330535-334411       Z28057.1           1-3877
            333970-335320       Z28056.1           1-1351
            334916-336536       Z28055.1           1-1621
            336158-339571       Z28054.1           1-3414
            338754-341311       Z28052.1           1-2558
            340547-342851       Z28051.1           1-2305
            342374-346074       Z28050.1           1-3701
            345621-347213       Z28049.1           1-1592
            346489-349462       Z28048.1           1-2973
            349137-351274       Z28047.1           1-2138
            351014-353492       Z28046.1           1-2479
            352625-356321       Z28045.1           1-3697
            355080-356747       Z28044.1           1-1668
            356643-358474       Z28043.1           1-1832
            357849-360142       Z28042.1           1-2293
            359567-361057       Z28041.1           1-1490
            360818-362621       Z28040.1           1-1804
            361829-365604       Z28039.1           1-3775
            364219-369364       Z28038.1           1-5146
            369118-371828       Z28035.1           1-2711
            371391-375455       Z28034.1           1-4064
            374106-380064       Z28033.1           1-5958
            378573-382071       Z28032.1           1-3499
            381859-382497       Z28031.1           1-639
            382486-385757       Z28029.1           1-3272
            384726-387561       Z28028.1           1-2836
            387207-389379       Z28027.1           1-2173
            388906-390239       Z28026.1           1-1334
            389884-392525       Z28025.1           1-2642
            392280-393720       Z28024.1           1-1441
            393141-394725       Z28023.1           1-1585
            394555-397343       Z28022.1           1-2789
            397249-398831       Z28021.1           1-1583
            398751-402567       Z28020.1           1-3817
            402081-404101       Z28019.1           1-2021
            403519-405189       Z28018.1           1-1671
            405092-407464       Z28017.1           1-2373
            407242-408543       Z28016.1           1-1302
            407990-411618       Z28015.1           1-3629
            411484-417507       Z28014.1           1-6024
            416914-418309       Z28013.1           1-1396
            418024-420154       Z28012.1           1-2131
            420062-421423       Z28011.1           1-1362
            421217-426241       Z28010.1           1-5025
            425876-427294       Z28009.1           1-1419
            426953-429301       Z28008.1           1-2349
            428552-431905       Z28007.1           1-3354
            430109-433092       Z28006.1           1-2984
            432433-435579       Z28005.1           1-3147
            434878-437096       Z28004.1           1-2219
            436786-438088       Z28003.1           1-1303
            437493-438776       Z28002.1           1-1284
            438545-440607       Z28001.1           1-2063
            439386-443231       Z28226.1           1-3846
            442723-445380       Z28227.1           1-2658
            444939-446798       Z28228.1           1-1860
            446728-448520       Z28229.1           1-1793
            447678-450422       Z28230.1           1-2745
            449865-451433       Z28231.1           1-1569
            451251-452200       Z28232.1           1-950
            451989-454351       Z28233.1           1-2363
            454079-458923       Z28234.1           1-4845
            457055-461634       Z28235.1           1-4580
            461240-463738       Z28236.1           1-2499
            462697-464116       Z28237.1           1-1420
            463959-465366       Z28238.1           1-1408
            464949-466960       Z28239.1           1-2012
            466072-469716       Z28240.1           1-3645
            468668-471693       Z28241.1           1-3026
            471340-473722       Z28242.1           1-2383
            473350-476215       Z28243.1           1-2866
            475901-478337       Z28244.1           1-2437
            478064-479233       Z28245.1           1-1170
            478833-482170       Z28246.1           1-3338
            481982-483418       Z28247.1           1-1437
            483140-485143       Z28248.1           1-2004
            485012-487769       Z28249.1           1-2758
            487373-488737       Z28250.1           1-1365
            488619-491363       Z28251.1           1-2745
            489656-494256       Z28252.1           1-4601
            493662-497577       Z28253.1           1-3915
            497555-500281       Z28254.1           1-2727
            499834-501343       Z28255.1           1-1510
            501104-506516       Z28256.1           1-5413
            506396-506878       Z28257.1           1-483
            506832-507304       Z28258.1           1-473
            506898-507919       Z28259.1           1-1022
            507708-508701       Z28260.1           1-994
            508562-510909       Z28261.1           1-2348
            510682-511998       Z28262.1           1-1317
            511798-515062       Z28263.1           1-3265
            513265-518062       Z28264.1           1-4798
            516872-518566       Z28265.1           1-1695
            518198-519271       Z28266.1           1-1074
            518951-520896       Z28267.1           1-1946
            520625-522014       Z28268.1           1-1390
            521713-523417       Z28269.1           1-1705
            523347-524222       Z28270.1           1-876
            523994-525256       Z28271.1           1-1263
            525075-525562       Z28272.1           1-488
            525387-526829       Z28273.1           1-1443
            526641-527814       Z28274.1           1-1174
            527232-530945       Z28275.1           1-3714
            530485-532549       Z28276.1           1-2065
            532203-534066       Z28277.1           1-1864
            533465-535646       Z28278.1           1-2182
            535282-548215       Z28279.1           1-12934
            547926-549447       Z28280.1           1-1522
            549092-551656       Z28281.1           1-2564
            551303-553177       Z28282.1           1-1875
            552003-554986       Z28283.1           1-2984
            554621-556517       Z28284.1           1-1897
            556175-557676       Z28285.1           1-1502
            557343-559665       Z28286.1           1-2323
            558955-560788       Z28287.1           1-1834
            560653-562546       Z28288.1           1-1894
            562298-565298       Z28289.1           1-3001
            565139-566112       Z28290.1           1-974
            565893-567917       Z28291.1           1-2025
            567199-570327       Z28292.1           1-3129
            570150-571611       Z28293.1           1-1462
            570910-573573       Z28294.1           1-2664
            573394-574933       Z28295.1           1-1540
            574633-576434       Z28296.1           1-1802
            575981-578186       Z28297.1           1-2206
            578124-579208       Z28298.1           1-1085
            578508-579826       Z28299.1           1-1319
            579677-582282       Z28300.1           1-2606
            580751-583652       Z28301.1           1-2902
            583396-584951       Z28302.1           1-1556
            584745-586788       Z28303.1           1-2044
            586710-590394       Z28304.1           1-3685
            589306-591505       Z28305.1           1-2200
            591358-592824       Z28306.1           1-1467
            592541-596420       Z28307.1           1-3880
            596299-597054       Z28308.1           1-756
            596823-599093       Z28309.1           1-2271
            598891-599856       Z28310.1           1-966
            599682-603194       Z28311.1           1-3513
            603073-604404       Z28312.1           1-1331
            604141-605632       Z28313.1           1-1492
            605419-608945       Z28314.1           1-3527
            608366-611806       Z28315.1           1-3440
            611067-612664       Z28316.1           1-1597
            612266-615729       Z28317.1           1-3464
            613886-617995       Z28318.1           1-4110
            617536-619804       Z28319.1           1-2269
            618743-626792       Z28320.1           1-8050
            625433-631151       Z28321.1           1-5715
            630381-633025       Z28322.1           1-2641
            632802-635850       Z28323.1           1-3049
            635180-639241       Z28324.1           1-4062
            638287-640467       Z28325.1           1-2180
            639969-646355       Z28326.1           1-6387
            642505-653079       Z28327.1           1-10575
            649866-656835       Z28328.1           1-6970
            656737-658715       Z28329.1           1-1979
            657757-661441       Z28330.1           1-3685
            660465-666816       Z28202.1           1-6352
FEATURES             Location/Qualifiers
     source          1..666816
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="genomic DNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XI"
     telomere        complement(1..807)
                     /note="TEL11L; Telomeric region on the left arm of
                     Chromosome XI; composed of an X element core sequence, X
                     element combinatorial repeats, and a short terminal
                     stretch of telomeric repeats"
                     /db_xref="SGD:S000028906"
     gene            complement(1810..2181)
                     /gene="PAU16"
                     /locus_tag="YKL224C"
     mRNA            complement(1810..2181)
                     /gene="PAU16"
                     /locus_tag="YKL224C"
                     /product="seripauperin PAU16"
     CDS             complement(1810..2181)
                     /gene="PAU16"
                     /locus_tag="YKL224C"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:26928762]"
                     /note="hypothetical protein; member of the seripauperin
                     multigene family encoded mainly in subtelomeric regions;
                     SWAT-GFP and mCherry fusion proteins localize to the
                     vacuole"
                     /codon_start=1
                     /product="seripauperin PAU16"
                     /protein_id="DAA08946.1"
                     /db_xref="SGD:S000001707"
                     /translation="MVKLTSIAAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVS
                     DIRAHLAQYYLFQAAHPSETYPVEIAEAVFNYGDFTTMLTGIPAEQVTRVITGVPWYS
                     TRLRPAISSALSKDGIYTIAN"
     gene            complement(3503..5620)
                     /locus_tag="YKL222C"
     mRNA            complement(3503..5620)
                     /locus_tag="YKL222C"
                     /product="hypothetical protein"
     CDS             complement(3503..5620)
                     /locus_tag="YKL222C"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:21777356]"
                     /experiment="EXISTENCE:direct assay:GO:0043565
                     sequence-specific DNA binding [PMID:19158363]"
                     /experiment="EXISTENCE:direct assay:GO:0072686 mitotic
                     spindle [PMID:21777356]"
                     /note="hypothetical protein; may interact with ribosomes,
                     based on co-purification experiments; similar to
                     transcriptional regulators from the zinc cluster
                     (binuclear cluster) family; null mutant is sensitive to
                     caffeine"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA08947.1"
                     /db_xref="SGD:S000001705"
                     /translation="MKNTELSQKKKLDRQSRRKPAKSCHFCRVRKLKCDRVRPFCGSC
                     SSRNRKQCEYKENTSAMEDQLRKKYRRCSKLEMARRIEELESQLTKQSQPNIHEGQNP
                     LSNMRYLSSKHNRHILYGPTSYRAILATQTDTFAKYREEIWQVLKLSRNNWKREHHYS
                     TLSEISSIETAPPHSGSPSVIEYLCESLPNYEVLCEYLTDFFASDFYDSYQIVHKEKV
                     LRDLQDCFVKGPRSHKTGQHTIISLNLDSKKNYYKVGVMTAIMCLASHPKEVPEAIEV
                     FHKVLTSFVSAKVFYTERVQFLFLRYLYINVAGLDGGDQSHCIFIHGLTIDTAIHMGL
                     NEDLRRLYLSKNHPIEEIPYLERLWLWILFTDVKISLSTGIPVRINDDFVNKVRLENY
                     SSSGDILLYKTTLRLRNIMKQIHAREKPPDIPLIIEDLKKFTIKMFKPLDFYLNASNL
                     NGNEFTELQLWHATLHMIGSLSNLYTLTHQDFDARIFNFSVLAPLNSLHLCFNVLETY
                     FELDNSKLSSKSLCLSKKWPHLNNALFLIYVNAFRALIQIYTIFLQYMENKDIQLFIQ
                     RNSSALTYSICPGDFEGPHNKCISLKIAFKEMENIFDHIHQEKLKPLTQIWQNSYYFS
                     IIISMEKIGRRAFNKGMKNIDEGPETENDATENSLTTILNDLEGPLEDFSENFIDDIL
                     GSPSAFFDTAISGWSNFEDFFSR"
     gene            6107..7528
                     /gene="MCH2"
                     /locus_tag="YKL221W"
     mRNA            6107..7528
                     /gene="MCH2"
                     /locus_tag="YKL221W"
                     /product="Mch2p"
     CDS             6107..7528
                     /gene="MCH2"
                     /locus_tag="YKL221W"
                     /note="Protein with similarity to mammalian
                     monocarboxylate permeases; monocarboxylate permeases are
                     involved in transport of monocarboxylic acids across the
                     plasma membrane but mutant is not deficient in
                     monocarboxylate transport"
                     /codon_start=1
                     /product="Mch2p"
                     /protein_id="DAA08948.2"
                     /db_xref="SGD:S000001704"
                     /translation="MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFI
                     LLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVIT
                     WLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLI
                     PLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCIICTSLSTIAL
                     MLTRTTHQGLRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTV
                     SLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHLVMAILCWAMWIPC
                     KNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPII
                     GLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNEL
                     HLNVKLSHMSKCLFRYKQLPRRV"
     rep_origin      7528..8309
                     /note="ARS1102; Putative replication origin; identified in
                     multiple array studies, not yet confirmed by plasmid-based
                     assay"
                     /db_xref="SGD:S000130137"
     gene            complement(9091..11226)
                     /gene="FRE2"
                     /locus_tag="YKL220C"
     mRNA            complement(9091..11226)
                     /gene="FRE2"
                     /locus_tag="YKL220C"
                     /product="ferric/cupric-chelate reductase"
     CDS             complement(9091..11226)
                     /gene="FRE2"
                     /locus_tag="YKL220C"
                     /EC_number="1.16.1.9"
                     /experiment="EXISTENCE:direct assay:GO:0000184
                     nuclear-transcribed mRNA catabolic process,
                     nonsense-mediated decay [PMID:31322728]"
                     /experiment="EXISTENCE:direct assay:GO:0000293
                     ferric-chelate reductase activity [PMID:8164662]"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005886 plasma
                     membrane [PMID:8164662]"
                     /experiment="EXISTENCE:direct assay:GO:0006826 iron ion
                     transport [PMID:8164662]"
                     /experiment="EXISTENCE:direct assay:GO:0015677 copper ion
                     import [PMID:9153234]"
                     /note="Ferric reductase and cupric reductase; reduces
                     siderophore-bound iron and oxidized copper prior to uptake
                     by transporters; expression induced by low iron levels but
                     not by low copper levels"
                     /codon_start=1
                     /product="ferric/cupric-chelate reductase"
                     /protein_id="DAA08949.1"
                     /db_xref="SGD:S000001703"
                     /translation="MHWTSILSAILLFCLSGARASPAKTVIRNKVPLLVTNACTRIFQ
                     KVTWEYTSKSKRSSPVCSYEPAFQSMLYCIYETLDEKGYSNKTLEKTFSTIKKNCASY
                     SDALQNMTNSEFYDVLNNGTRHMTPYVKGSANLTYPVEMDTQLRKAYYHALHGFYANL
                     DVGNIYGGIICAYFVAIMAFAGVLHCMNYTPFKTVLLKQKLVGYVRGYLTLPTIGSKH
                     ASDFSYFRIFTGYLPTRLEGIIILGYLVLHTVFLAYGYEYDPENIIFKSRRVQVARYV
                     ADRSGVLAFAHFPLIVLFAGRNNFLEYISGVKYTSFIMFHKWLGRMMFLDAMIHGSAY
                     TSYTVANKTWATSKNRLYWQFGVAALCLAGTMVFFSFAVFRKYFYEAFLFLHIVLGAM
                     FFYACWEHVVSLSGIEWIYTAIAIWIVDRIIRIIKASYFGFPKASLQLIGDDLIRLTV
                     KKPARPWRAKPGQYVFVSFLHPLYFWQSHPFTVLDSVSKNGELVIILKEKKGVTRLVK
                     KYVCRNGGKTSMRLAIEGPYGSSSPVNNYNNVLLLTGGTGLPGPIAHAIKLGKTSAAA
                     GKQSVKLVIAVRGFDVLEAYKPELMCLENLNVQLHIYNTMEVPSLTPSDSLDISQQDE
                     KADEKGTVVATTLEKSANPLGFDGVVFHCGRPNVKELLHEAAELSGSLSVVCCGPPIF
                     VDKVRNETAKIVLDKSAKAIEYFEEYQCW"
     gene            14485..15708
                     /gene="COS9"
                     /locus_tag="YKL219W"
     mRNA            14485..15708
                     /gene="COS9"
                     /locus_tag="YKL219W"
                     /product="Cos9p"
     CDS             14485..15708
                     /gene="COS9"
                     /locus_tag="YKL219W"
                     /note="Endosomal protein involved in turnover of plasma
                     membrane proteins; member of the DUP380 subfamily of
                     conserved, often subtelomeric COS genes; required for the
                     multivesicular vesicle body sorting pathway that
                     internalizes plasma membrane proteins for degradation; Cos
                     proteins provide ubiquitin in trans for nonubiquitinated
                     cargo proteins"
                     /codon_start=1
                     /product="Cos9p"
                     /protein_id="DAA08950.1"
                     /db_xref="SGD:S000001702"
                     /translation="MQIVRSCNSNNKPLIPSSNWHIAIRMRGDGVKDRSIDVLSLKHF
                     ESQKVVLPQDLFMDNFTWMFYEFFKCFTFRTWLLLLLLMWLPGFLSQIKSINRIFPFK
                     LCILVSCLVGIFLPNIYSFSHKSVLTNQLTQFSKEIVEHAPGTDTHDWETVAANLNSY
                     FYENKAWNTEYFFFNAAECQKAFRKVLLEPFSVKKDESSKIKSFGDSVPYIEEALQVY
                     STEFDKKWKLFNTEKVWSPDNLEHVQLPKKTYRYKFTWVLKRIFNLWLFPAFILFLAC
                     IYVSWDKGHLFRILCCGGGFLLMVRVFQNMRPFSMHMEDKMQFLSTIINEQESGANGW
                     DEIAKKMNRYLFEKKVWTSEEFFFDGIDCEWFFNHFFYRLLSTKKPMFDRPLNVELWP
                     YIKEAQLTRKQAPPV"
     gene            complement(17359..18339)
                     /gene="SRY1"
                     /locus_tag="YKL218C"
     mRNA            complement(17359..18339)
                     /gene="SRY1"
                     /locus_tag="YKL218C"
                     /product="threo-3-hydroxy-L-aspartate ammonia-lyase SRY1"
     CDS             complement(17359..18339)
                     /gene="SRY1"
                     /locus_tag="YKL218C"
                     /EC_number="4.3.1.16"
                     /experiment="EXISTENCE:direct assay:GO:0030848
                     threo-3-hydroxyaspartate ammonia-lyase activity
                     [PMID:12951240]"
                     /experiment="EXISTENCE:direct assay:GO:0042219 cellular
                     modified amino acid catabolic process [PMID:12951240]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030848
                     threo-3-hydroxyaspartate ammonia-lyase activity
                     [PMID:12951240]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042219
                     cellular modified amino acid catabolic process
                     [PMID:12951240]"
                     /note="3-hydroxyaspartate dehydratase; deaminates
                     L-threo-3-hydroxyaspartate to form oxaloacetate and
                     ammonia; required in the presence of hydroxyaspartate;
                     highly similar to mouse serine racemase (Srr) but has no
                     serine racemase activity"
                     /codon_start=1
                     /product="threo-3-hydroxy-L-aspartate ammonia-lyase SRY1"
                     /protein_id="DAA08951.1"
                     /db_xref="SGD:S000001701"
                     /translation="MIVPTYGDVLDASNRIKEYVNKTPVLTSRMLNDRLGAQIYFKGE
                     NFQRVGAFKFRGAMNAVSKLSDEKRSKGVIAFSSGNHAQAIALSAKLLNVPATIVMPE
                     DAPALKVAATAGYGAHIIRYNRYTEDREQIGRQLAAEHGFALIPPYDHPDVIAGQGTS
                     AKELLEEVGQLDALFVPLGGGGLLSGSALAARSLSPGCKIFGVEPEAGNDGQQSFRSG
                     SIVHINTPKTIADGAQTQHLGEYTFAIIRENVDDILTVSDQELVKCMHFLAERMKVVV
                     EPTACLGFAGALLKKEELVGKKVGIILSGGNVDMKRYATLISGKEDGPTI"
     gene            22234..24084
                     /gene="JEN1"
                     /locus_tag="YKL217W"
     mRNA            22234..24084
                     /gene="JEN1"
                     /locus_tag="YKL217W"
                     /product="Jen1p"
     CDS             22234..24084
                     /gene="JEN1"
                     /locus_tag="YKL217W"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0005886 plasma
                     membrane [PMID:17710650]"
                     /experiment="EXISTENCE:direct assay:GO:0071944 cell
                     periphery [PMID:26928762]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006849 plasma
                     membrane pyruvate transport [PMID:17710650]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015355
                     secondary active monocarboxylate transmembrane transporter
                     activity [PMID:17710650]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0035879 plasma
                     membrane lactate transport [PMID:10198029|PMID:17710650]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0097079
                     selenite:proton symporter activity [PMID:20861301]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0097080 plasma
                     membrane selenite transport [PMID:20861301]"
                     /note="Monocarboxylate/proton symporter of the plasma
                     membrane; transport activity is dependent on the pH
                     gradient across the membrane; mediates high-affinity
                     uptake of carbon sources lactate, pyuvate, and acetate,
                     and also of the micronutrient selenite, whose structure
                     mimics that of monocarboxylates; expression and
                     localization are tightly regulated, with transcription
                     repression, mRNA degradation, and protein endocytosis and
                     degradation all occurring in the presence of glucose"
                     /codon_start=1
                     /product="Jen1p"
                     /protein_id="DAA08952.1"
                     /db_xref="SGD:S000001700"
                     /translation="MSSSITDEKISGEQQQPAGRKLYYNTSTFAEPPLVDGEGNPINY
                     EPEVYNPDHEKLYHNPSLPAQSIQDTRDDELLERVYSQDQGVEYEEDEEDKPNLSAAS
                     IKSYALTRFTSLLHIHEFSWENVNPIPELRKMTWQNWNYFFMGYFAWLSAAWAFFCVS
                     VSVAPLAELYDRPTKDITWGLGLVLFVRSAGAVIFGLWTDKSSRKWPYITCLFLFVIA
                     QLCTPWCDTYEKFLGVRWITGIAMGGIYGCASATAIEDAPVKARSFLSGLFFSAYAMG
                     FIFAIIFYRAFGYFRDDGWKILFWFSIFLPILLIFWRLLWPETKYFTKVLKARKLILS
                     DAVKANGGEPLPKANFKQKMVSMKRTVQKYWLLFAYLVVLLVGPNYLTHASQDLLPTM
                     LRAQLGLSKDAVTVIVVVTNIGAICGGMIFGQFMEVTGRRLGLLIACTMGGCFTYPAF
                     MLRSEKAILGAGFMLYFCVFGVWGILPIHLAELAPADARALVAGLSYQLGNLASAAAS
                     TIETQLADRYPLERDASGAVIKEDYAKVMAILTGSVFIFTFACVFVGHEKFHRDLSSP
                     VMKKYINQVEEYEADGLSISDIVEQKTECASVKMIDSNVSKTYEEHIETV"
     gene            25215..26159
                     /gene="URA1"
                     /locus_tag="YKL216W"
     mRNA            25215..26159
                     /gene="URA1"
                     /locus_tag="YKL216W"
                     /product="dihydroorotate dehydrogenase"
     CDS             25215..26159
                     /gene="URA1"
                     /locus_tag="YKL216W"
                     /EC_number="1.3.98.1"
                     /experiment="EXISTENCE:direct assay:GO:0004152
                     dihydroorotate dehydrogenase activity [PMID:1511880]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:1409592]"
                     /experiment="EXISTENCE:direct assay:GO:0006207 'de novo'
                     pyrimidine nucleobase biosynthetic process
                     [PMID:10871048]"
                     /experiment="EXISTENCE:direct assay:GO:0019898 extrinsic
                     component of membrane [PMID:11921093]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004152
                     dihydroorotate dehydrogenase activity [PMID:4550660]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006207 'de
                     novo' pyrimidine nucleobase biosynthetic process
                     [PMID:4550660|PMID:5651325]"
                     /note="Dihydroorotate dehydrogenase; catalyzes the fourth
                     enzymatic step in the de novo biosynthesis of pyrimidines,
                     converting dihydroorotic acid into orotic acid"
                     /codon_start=1
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="DAA08953.1"
                     /db_xref="SGD:S000001699"
                     /translation="MTASLTTKFLNNTYENPFMNASGVHCMTTQELDELANSKAGAFI
                     TKSATTLEREGNPEPRYISVPLGSINSMGLPNEGIDYYLSYVLNRQKNYPDAPAIFFS
                     VAGMSIDENLNLLRKIQDSEFNGITELNLSCPNVPGKPQVAYDFDLTKETLEKVFAFF
                     KKPLGVKLPPYFDFAHFDIMAKILNEFPLAYVNSINSIGNGLFIDVEKESVVVKPKNG
                     FGGIGGEYVKPTALANVRAFYTRLRPEIKVIGTGGIKSGKDAFEHLLCGASMLQIGTE
                     LQKEGVKIFERIEKELKDIMEAKGYTSIDQFRGKLNSI"
     gene            complement(26827..30687)
                     /gene="OXP1"
                     /locus_tag="YKL215C"
     mRNA            complement(26827..30687)
                     /gene="OXP1"
                     /locus_tag="YKL215C"
                     /product="5-oxoprolinase"
     CDS             complement(26827..30687)
                     /gene="OXP1"
                     /locus_tag="YKL215C"
                     /EC_number="3.5.2.9"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095|PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0017168
                     5-oxoprolinase (ATP-hydrolyzing) activity [PMID:20402795]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006749
                     glutathione metabolic process [PMID:20349993]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0017168
                     5-oxoprolinase (ATP-hydrolyzing) activity [PMID:20402795]"
                     /note="5-oxoprolinase; enzyme is ATP-dependent and
                     functions as a dimer; similar to mouse Oplah gene; green
                     fluorescent protein (GFP)-fusion protein localizes to the
                     cytoplasm; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="5-oxoprolinase"
                     /protein_id="DAA08954.1"
                     /db_xref="SGD:S000001698"
                     /translation="MQKGNIRIAIDKGGTFTDCVGNIGTGKQEHDTVIKLLSVDPKNY
                     PDAPLEGIRRLLEVLEHKTIPRGIPLDISNVRSLRMGTTLATNCALERNGERCAFITT
                     KGFKDSLLIGDQTRPDIFNLNIKKVVPLYDTVVEIDERVTLEDFSEDPYFTKSSPNEQ
                     EGILEGNSGEMVRVIKKPDESSVRSILKVLYASGIKSIAIAFLHSYTFPDHERIVGNI
                     AREIGFSHVSLSSEVSPMIKFLPRAHSSVADAYLTPVIKKYLNSISAGLSHAEDTHIQ
                     FMQSDGGLVDGGKFSGLKSILSGPAGGVIGYSSTCYDKNNNIPLIGFDMGGTSTDVSR
                     YGDGRLEHVFETVTAGIIIQSPQLDIHTVAAGGSSILSWKNGLFRVGPDSAAADPGPA
                     AYRKGGPLTITDANLFLGRLVPEFFPKIFGPNEDESLDLETTTLKFRELTDVINKDLN
                     SNLTMEEVAYGFIKVANECMARPVRAITEAKGHVVSQHRLVSFGGAGGQHAIAVADSL
                     GIDTVLIHRYSSILSAYGIFLADVIEENQEPCSFILGEPETILKVKKRFLELSKNSIK
                     NLLSQSFSREDIVLERYLNLRYEGTETSLMILQKYDDQWNFREWFSEAHKKEFGFSFD
                     DKRIIIDDIRIRAIGKSGVRKEKTVDEQLIEISHFKKADVSKDASFTQKAYFDNKWVD
                     TAVFKIDDLPAGTIIEGPAILADGTQTNIILPNSQATILNSHIFIKINQKAAKTLSKS
                     GYELDIDPILLSIFSHRFMDIALQMGTQLRKTSVSTNVKERLDFSCALFDSKGNLVAN
                     APHVPVHLGSMSTCISAQAKLWEGKLKPGDVLITNHPDIGGTHLPDITVITPSFSSTG
                     ELIFYVASRAHHADIGGILPGSVPPNSKELYEEGTAIYSELVVKEGIFQEELIYKLFV
                     EDPGKYPGCSGSRRFSDNISDLKAQVAANTKGIQLIGSLTKEYDLATILKYMAAIQTN
                     ASESIKKMLAKMVEHFGTTKFSGEDRLDDGSLIKLQVIIRPEKEEYIFNFDGTSPQVY
                     GNLNAPEAITNSAILYCLRCLVGEDIPLNQGCLKPLTIKIPAGSLLSPRSGAAVVGGN
                     VLTSQRVTDVILKTFNVMADSQGDCNNFTFGTGGNSGNKTDKQIKGFGYYETICGGSG
                     AGADSWRGSGWNGSDAVHTNMTNTRMTDTEVFERRYPVLLKEFSIRRGSGGKGKYTGG
                     NGVVRDVQFRKAVTASILSERRVIGPHGIKGGQDGSRGENLWVRHSTGALINVGGKNT
                     IYAQPGDRFIIKTPGGGGFGQYKD"
     gene            complement(31082..31693)
                     /gene="YRA2"
                     /locus_tag="YKL214C"
     mRNA            complement(31082..31693)
                     /gene="YRA2"
                     /locus_tag="YKL214C"
                     /product="Yra2p"
     CDS             complement(31082..31693)
                     /gene="YRA2"
                     /locus_tag="YKL214C"
                     /experiment="EXISTENCE:direct assay:GO:0003723 RNA binding
                     [PMID:11390651]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:11390651]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016973
                     poly(A)+ mRNA export from nucleus [PMID:11390651]"
                     /note="Member of the REF (RNA and export factor binding
                     proteins) family; when overexpressed, can substitute for
                     the function of Yra1p in export of poly(A)+ mRNA from the
                     nucleus"
                     /codon_start=1
                     /product="Yra2p"
                     /protein_id="DAA08955.1"
                     /db_xref="SGD:S000001697"
                     /translation="MDKAFDEIIGNSHTDSSSNHKVTRYRRRDLRNELGPRLGFAPSD
                     AASRSKDRLYREREEPPLPKRIRISKIPLDVSDYTLDDMIKEFGSPIFSKIFDNKEDR
                     TCIYEFEDPEVLEKIVERYNGHELHNAKIEVEIYQPQRKHSRMNAHNRRKQTAQEHGR
                     GRPGSHYRQKPNRVSKKNKGREKNNTPTSVEALDAELDAYMKG"
     gene            complement(31960..34107)
                     /gene="DOA1"
                     /locus_tag="YKL213C"
                     /gene_synonym="UFD3"
                     /gene_synonym="ZZZ4"
     mRNA            complement(31960..34107)
                     /gene="DOA1"
                     /locus_tag="YKL213C"
                     /gene_synonym="UFD3"
                     /gene_synonym="ZZZ4"
                     /product="Doa1p"
     CDS             complement(31960..34107)
                     /gene="DOA1"
                     /locus_tag="YKL213C"
                     /gene_synonym="UFD3"
                     /gene_synonym="ZZZ4"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:14562095|PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095|PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0043130 ubiquitin
                     binding [PMID:16428438|PMID:21070969]"
                     /experiment="EXISTENCE:genetic interaction:GO:0043161
                     proteasome-mediated ubiquitin-dependent protein catabolic
                     process [PMID:23525333]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006303
                     double-strand break repair via nonhomologous end joining
                     [PMID:12399380]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0010992
                     ubiquitin recycling
                     [PMID:18508771|PMID:19805280|PMID:7615550]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0034517
                     ribophagy [PMID:20508643]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0043130
                     ubiquitin binding [PMID:16428438]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0043161
                     proteasome-mediated ubiquitin-dependent protein catabolic
                     process [PMID:2111732|PMID:23525333]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0072671
                     mitochondria-associated ubiquitin-dependent protein
                     catabolic process [PMID:32118579|PMID:21070972]"
                     /note="WD-repeat protein involved in ubiquitin-mediated
                     protein degradation; Ub-binding protein with a role in Ub
                     homeostasis; substrate-recruiting adaptor for Cdc48p in
                     mitochondria-associated degradation; inhibits degradation
                     of Ufd2p-dependent substrates; facilitates proteolysis of
                     Cse4p, a centromeric H3-like protein; required for
                     ribophagy; promotes NHEJ in postdiauxic/stationary phase;
                     protein increases in abundance and relocalizes from
                     nucleus to nuclear periphery upon DNA replication stress"
                     /codon_start=1
                     /product="Doa1p"
                     /protein_id="DAA08956.1"
                     /db_xref="SGD:S000001696"
                     /translation="MGYQLSATLKGHDQDVRDVVAVDDSKVASVSRDGTVRLWSKDDQ
                     WLGTVVYTGQGFLNSVCYDSEKELLLFGGKDTMINGVPLFATSGEDPLYTLIGHQGNV
                     CSLSFQDGVVISGSWDKTAKVWKEGSLVYNLQAHNASVWDAKVVSFSENKFLTASADK
                     TIKLWQNDKVIKTFSGIHNDVVRHLAVVDDGHFISCSNDGLIKLVDMHTGDVLRTYEG
                     HESFVYCIKLLPNGDIVSCGEDRTVRIWSKENGSLKQVITLPAISIWSVDCMSNGDII
                     VGSSDNLVRIFSQEKSRWASEDEINELSTQVEKSTISSKTIEFDESKLSPYEILQSPG
                     RKEGQIVVVKSPQGTIEAHQFSNSSWKKVGDVVGAGATGNDKKIEFEGKTYDYVFDVD
                     IEDGKPPLKLPINVSDNPYTAADNFLARYELPMSYRDQVVQFILKNTNGISLDQPNDN
                     ASSSAVSPSKTSVMKVLPVKQYLIMENYNPDTIFNGIVKINSNEKTFDDEILAQIGGA
                     LHDIDESWELLLSFANTIRSNWEIKTPAYDIVRLIVKKLPYSSDIKDYIEEGLGNKNI
                     TLTMLTVRILVNCFNNENWGVKLLESNQVYKSIFETIDTEFSQASAKQSQNLAIAVST
                     LIFNYSALVTKGNSDLELLPIVADAINTKYGPLEEYQECEEAAYRLTVAYGNLATVEP
                     TLRQFANSVTWLANIKRSYGNVPRFKDIFDDLS"
     gene            34543..36414
                     /gene="SAC1"
                     /locus_tag="YKL212W"
                     /gene_synonym="RSD1"
     mRNA            34543..36414
                     /gene="SAC1"
                     /locus_tag="YKL212W"
                     /gene_synonym="RSD1"
                     /product="phosphatidylinositol-3-phosphatase SAC1"
     CDS             34543..36414
                     /gene="SAC1"
                     /locus_tag="YKL212W"
                     /gene_synonym="RSD1"
                     /EC_number="3.1.3.64"
                     /experiment="EXISTENCE:direct assay:GO:0004438
                     phosphatidylinositol-3-phosphatase activity
                     [PMID:10625610]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0005741
                     mitochondrial outer membrane [PMID:16407407]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005797 Golgi
                     medial cisterna [PMID:22553352]"
                     /experiment="EXISTENCE:direct assay:GO:0030173 integral
                     component of Golgi membrane [PMID:15657391|PMID:8314848]"
                     /experiment="EXISTENCE:direct assay:GO:0030176 integral
                     component of endoplasmic reticulum membrane
                     [PMID:11514624|PMID:15657391|PMID:8314848]"
                     /experiment="EXISTENCE:direct assay:GO:0032541 cortical
                     endoplasmic reticulum [PMID:30785834]"
                     /experiment="EXISTENCE:direct assay:GO:0035339 SPOTS
                     complex [PMID:20182505]"
                     /experiment="EXISTENCE:direct assay:GO:0043812
                     phosphatidylinositol-4-phosphate phosphatase activity
                     [PMID:10625610]"
                     /experiment="EXISTENCE:direct assay:GO:0046856
                     phosphatidylinositol dephosphorylation [PMID:10625610]"
                     /experiment="EXISTENCE:direct assay:GO:0052629
                     phosphatidylinositol-3,5-bisphosphate 3-phosphatase
                     activity [PMID:10625610]"
                     /experiment="EXISTENCE:genetic interaction:GO:0046856
                     phosphatidylinositol dephosphorylation [PMID:10625610]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030173
                     integral component of Golgi membrane [PMID:15657391]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030176
                     integral component of endoplasmic reticulum membrane
                     [PMID:11514624|PMID:11792713|PMID:15657391]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0046856
                     phosphatidylinositol dephosphorylation
                     [PMID:10625610|PMID:22553352]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0061909
                     autophagosome-lysosome fusion [PMID:32693712]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0072517 host
                     cell viral assembly compartment [PMID:32269127]"
                     /note="Phosphatidylinositol phosphate phosphatase; role in
                     early and medial Golgi PtdIns4P hydrolysis; regulated by
                     Vps74p interaction; ER localized transmembrane protein
                     which cycles through the Golgi; role in protein
                     trafficking, processing, secretion, and cell wall
                     maintenance; regulates sphingolipid biosynthesis by
                     modulating PtdIns(4)P metabolism; PtdIns4P PPase activity
                     is crucial for autophagosome-vacuole fusion during
                     autophagy; human homolog SACM1L complements autophagy
                     defects of the null"
                     /codon_start=1
                     /product="phosphatidylinositol-3-phosphatase SAC1"
                     /protein_id="DAA08957.1"
                     /db_xref="SGD:S000001695"
                     /translation="MTGPIVYVQNADGIFFKLAEGKGTNDAVIHLANQDQGVRVLGAE
                     EFPVQGEVVKIASLMGFIKLKLNRYAIIANTVEETGRFNGHVFYRVLQHSIVSTKFNS
                     RIDSEEAEYIKLLELHLKNSTFYFSYTYDLTNSLQRNEKVGPAASWKTADERFFWNHY
                     LTEDLRNFAHQDPRIDSFIQPVIYGYAKTVDAVLNATPIVLGLITRRSIFRAGTRYFR
                     RGVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEINNLKYKPNLV
                     LGENSLDATKKHFDQQKELYGDNYLVNLVNQKGHELPVKEGYESVVHALNDPKIHYVY
                     FDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRTNC
                     MDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAPLLTSYQNLWADNADAVSV
                     AYSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGGFRPH
                     TASIKSPFPDRRPVYIQLIPMIICAALTVLGATIFFPKDRFTSSKNLLYFAGASIVLA
                     LSTKFMFKNGIQFVNWPKLVDVGFLVVHQTHDKEQQFKGLKYAQSPKFSKPDPLKRD"
     gene            complement(36699..38153)
                     /gene="TRP3"
                     /locus_tag="YKL211C"
     mRNA            complement(36699..38153)
                     /gene="TRP3"
                     /locus_tag="YKL211C"
                     /product="bifunctional anthranilate
                     synthase/indole-3-glycerol-phosphate synthase"
     CDS             complement(36699..38153)
                     /gene="TRP3"
                     /locus_tag="YKL211C"
                     /EC_number="4.1.1.48"
                     /EC_number="4.1.3.27"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:genetic interaction:GO:0004049
                     anthranilate synthase activity [PMID:3881257]"
                     /experiment="EXISTENCE:genetic interaction:GO:0004425
                     indole-3-glycerol-phosphate synthase activity
                     [PMID:6323449]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000162
                     tryptophan biosynthetic process [PMID:10790693]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004425
                     indole-3-glycerol-phosphate synthase activity
                     [PMID:3881257]"
                     /experiment="EXISTENCE:physical interaction:GO:0005950
                     anthranilate synthase complex [PMID:3881257]"
                     /note="Indole-3-glycerol-phosphate synthase; forms
                     bifunctional hetero-oligomeric anthranilate
                     synthase:indole-3-glycerol phosphate synthase enzyme
                     complex with Trp2p"
                     /codon_start=1
                     /product="bifunctional anthranilate
                     synthase/indole-3-glycerol-phosphate synthase"
                     /protein_id="DAA08958.1"
                     /db_xref="SGD:S000001694"
                     /translation="MSVHAATNPINKHVVLIDNYDSFTWNVYEYLCQEGAKVSVYRND
                     AITVPEIAALNPDTLLISPGPGHPKTDSGISRDCIRYFTGKIPVFGICMGQQCMFDVF
                     GGEVAYAGEIVHGKTSPISHDNCGIFKNVPQGIAVTRYHSLAGTESSLPSCLKVTAST
                     ENGIIMGVRHKKYTVEGVQFHPESILTEEGHLMIRNILNVSGGTWEENKSSPSNSILD
                     RIYARRKIDVNEQSKIPGFTFQDLQSNYDLGLAPPLQDFYTVLSSSHKRAVVLAEVKR
                     ASPSKGPICLKAVAAEQALKYAEAGASAISVLTEPHWFHGSLQDLVNVRKILDLKFPP
                     KERPCVLRKEFIFSKYQILEARLAGADTVLLIVKMLSQPLLKELYSYSKDLNMEPLVE
                     VNSKEELQRALEIGAKVVGVNNRDLHSFNVDLNTTSNLVESIPKDVLLIALSGITTRD
                     DAEKYKKEGVHGFLVGEALMKSTDVKKFIHELCE"
     gene            38811..38911
                     /gene="SNR64"
                     /locus_tag="YNCK0001W"
     ncRNA           38811..38911
                     /ncRNA_class="snoRNA"
                     /gene="SNR64"
                     /locus_tag="YNCK0001W"
                     /product="SNR64"
                     /experiment="EXISTENCE:curator inference:GO:0005730
                     nucleolus [PMID:10024243]"
                     /experiment="EXISTENCE:curator inference:GO:0031428 box
                     C/D RNP complex [PMID:10024243]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030562 rRNA
                     2'-O-ribose methylation guide activity [PMID:10024243]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031167 rRNA
                     methylation [PMID:10024243]"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of large subunit (LSU) rRNA at position
                     C2337"
                     /db_xref="SGD:S000006455"
     gene            39163..42237
                     /gene="UBA1"
                     /locus_tag="YKL210W"
     mRNA            39163..42237
                     /gene="UBA1"
                     /locus_tag="YKL210W"
                     /product="E1 ubiquitin-activating protein UBA1"
     CDS             39163..42237
                     /gene="UBA1"
                     /locus_tag="YKL210W"
                     /EC_number="6.2.1.45"
                     /experiment="EXISTENCE:direct assay:GO:0004839 ubiquitin
                     activating enzyme activity [PMID:1989885]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:7629121|PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:7629121|PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0016567 protein
                     ubiquitination [PMID:1989885]"
                     /note="Ubiquitin activating enzyme (E1); involved in
                     ubiquitin-mediated protein degradation and essential for
                     viability; protein abundance increases in response to DNA
                     replication stress"
                     /codon_start=1
                     /product="E1 ubiquitin-activating protein UBA1"
                     /protein_id="DAA08959.1"
                     /db_xref="SGD:S000001693"
                     /translation="MSSNNSGLSAAGEIDESLYSRQLYVLGKEAMLKMQTSNVLILGL
                     KGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAEL
                     NAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLF
                     GNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPDGTVTMLDDNRHGLEDGNFVRFSEVEG
                     LDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNP
                     EFVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQP
                     EVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFD
                     SLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEML
                     KNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPD
                     LKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLES
                     GTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYF
                     TDSAENVNMYLTQPNFVEQTLKQSGDVKGVLESISDSLSSKPHNFEDCIKWARLEFEK
                     KFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAY
                     NYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPNANAANGSDEI
                     DQLVSSLPDPSTLAGFKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTK
                     FIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIAS
                     PKGEYNNKKYDKIWDRFDIKGDIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPK
                     KLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGEDVEVPFITIHL"
     gene            complement(42423..46295)
                     /gene="STE6"
                     /locus_tag="YKL209C"
     mRNA            complement(42423..46295)
                     /gene="STE6"
                     /locus_tag="YKL209C"
                     /product="ATP-binding cassette a-factor transporter STE6"
     CDS             complement(42423..46295)
                     /gene="STE6"
                     /locus_tag="YKL209C"
                     /EC_number="7.4.2.7"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005794 Golgi
                     apparatus [PMID:8045256]"
                     /experiment="EXISTENCE:direct assay:GO:0005886 plasma
                     membrane [PMID:7679674]"
                     /experiment="EXISTENCE:direct assay:GO:0015440 ABC-type
                     peptide transporter activity [PMID:11389139|PMID:8626301]"
                     /experiment="EXISTENCE:direct assay:GO:0043332 mating
                     projection tip [PMID:12374868|PMID:7679674]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000770 peptide
                     pheromone export [PMID:2569166]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015440
                     ABC-type peptide transporter activity
                     [PMID:11389139|PMID:8626301]"
                     /note="Plasma membrane ATP-binding cassette (ABC)
                     transporter; required for the export of a-factor,
                     catalyzes ATP hydrolysis coupled to a-factor transport;
                     contains 12 transmembrane domains and two ATP binding
                     domains; expressed only in MATa cells; human homolog ABCB1
                     mediates multidrug resistance in many
                     chemotherapy-resistant tumors by effluxing toxic compounds
                     from the cell"
                     /codon_start=1
                     /product="ATP-binding cassette a-factor transporter STE6"
                     /protein_id="DAA08960.1"
                     /db_xref="SGD:S000001692"
                     /translation="MNFLSFKTTKHYHIFRYVNIRNDYRLLMIMIIGTVATGLVPAIT
                     SILTGRVFDLLSVFVANGSHQGLYSQLVQRSMAVMALGAASVPVMWLSLTSWMHIGER
                     QGFRIRSQILEAYLEEKPMEWYDNNEKLLGDFTQINRCVEELRSSSAEASAITFQNLV
                     AICALLGTSFYYSWSLTLIILCSSPIITFFAVVFSRMIHVYSEKENSETSKAAQLLTW
                     SMNAAQLVRLYCTQRLERKKFKEIILNCNTFFIKSCFFVAANAGILRFLTLTMFVQGF
                     WFGSAMIKKGKLNINDVITCFHSCIMLGSTLNNTLHQIVVLQKGGVAMEKIMTLLKDG
                     SKRNPLNKTVAHQFPLDYATSDLTFANVSFSYPSRPSEAVLKNVSLNFSAGQFTFIVG
                     KSGSGKSTLSNLLLRFYDGYNGSISINGHNIQTIDQKLLIENITVVEQRCTLFNDTLR
                     KNILLGSTDSVRNADCSTNENRHLIKDACQMALLDRFILDLPDGLETLIGTGGVTLSG
                     GQQQRVAIARAFIRDTPILFLDEAVSALDIVHRNLLMKAIRHWRKGKTTIILTHELSQ
                     IESDDYLYLMKEGEVVESGTQSELLADPTTTFSTWYHLQNDYSDAKTIVDTETEEKSI
                     HTVESFNSQLETPKLGSCLSNLGYDETDQLSFYEAIYQKRSNVRTRRVKVEEENIGYA
                     LKQQKNTESSTGPQLLSIIQIIKRMIKSIRYKKILILGLLCSLIAGATNPVFSYTFSF
                     LLEGIVPSTDGKTGSSHYLAKWSLLVLGVAAADGIFNFAKGFLLDCCSEYWVMDLRNE
                     VMEKLTRKNMDWFSGENNKASEISALVLNDLRDLRSLVSEFLSAMTSFVTVSTIGLIW
                     ALVSGWKLSLVCISMFPLIIIFSAIYGGILQKCETDYKTSVAQLENCLYQIVTNIKTI
                     KCLQAEFHFQLTYHDLKIKMQQIASKRAIATGFGISMTNMIVMCIQAIIYYYGLKLVM
                     IHEYTSKEMFTTFTLLLFTIMSCTSLVSQIPDISRGQRAASWIYRILDEKHNTLEVEN
                     NNARTVGIAGHTYHGKEKKPIVSIQNLTFAYPSAPTAFVYKNMNFDMFCGQTLGIIGE
                     SGTGKSTLVLLLTKLYNCEVGKIKIDGTDVNDWNLTSLRKEISVVEQKPLLFNGTIRD
                     NLTYGLQDEILEIEMYDALKYVGIHDFVISSPQGLDTRIDTTLLSGGQAQRLCIARAL
                     LRKSKILILDECTSALDSVSSSIINEIVKKGPPALLTMVITHSEQMMRSCNSIAVLKD
                     GKVVERGNFDTLYNNRGELFQIVSNQSS"
     gene            complement(46735..46806)
                     /gene="TRT2"
                     /locus_tag="YNCK0002C"
     tRNA            complement(46735..46806)
                     /gene="TRT2"
                     /locus_tag="YNCK0002C"
                     /product="tRNA-Thr"
                     /experiment="EXISTENCE:curator inference:GO:0005829
                     cytosol [PMID:9023104]"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /note="Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE
                     analysis; correct folding and efficient aminoacylation
                     require Lhp1p"
                     /db_xref="SGD:S000006748"
     gene            47157..47972
                     /gene="CBT1"
                     /locus_tag="YKL208W"
                     /gene_synonym="SOC1"
     mRNA            47157..47972
                     /gene="CBT1"
                     /locus_tag="YKL208W"
                     /gene_synonym="SOC1"
                     /product="Cbt1p"
     CDS             47157..47972
                     /gene="CBT1"
                     /locus_tag="YKL208W"
                     /gene_synonym="SOC1"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0006397 mRNA
                     processing [PMID:9339340]"
                     /experiment="EXISTENCE:direct assay:GO:0017004 cytochrome
                     complex assembly [PMID:9339340]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006397 mRNA
                     processing [PMID:16118200|PMID:9339340]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0017004
                     cytochrome complex assembly [PMID:9339340]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0048255 mRNA
                     stabilization [PMID:16118200]"
                     /note="Protein involved in 5' RNA end processing;
                     substrates include mitochondrial COB, 15S_rRNA, and RPM1
                     transcripts; may also have a role in 3' end processing of
                     the COB pre-mRNA; displays genetic interaction with cell
                     cycle-regulated kinase Dbf2p"
                     /codon_start=1
                     /product="Cbt1p"
                     /protein_id="DAA08961.1"
                     /db_xref="SGD:S000001691"
                     /translation="MVSYGSHSSEVSKVLKTPKFVLRYGNVSSKQRFALKRKINYKLR
                     ESKYQEYLNEYNTFVLYDWENSGAGSLVDSSYNLPSLWKEFITEGISKGAINDKLPTV
                     FMKRKLTNSALGHCLGLDFLTDPSESEHEYRCMFQTVQDIPSLSQLILFNSMPNVPVR
                     LKLHTIGININFGCKRSLISNGGDQDTEMSEAVSYIQPLLEESSRMYRNLNYWKLLKI
                     ARNNKKDEPLDQSTRIKSQVKLLLSQLATNRITSPSVTDHGGHNWLIFTRRRL"
     gene            48194..48955
                     /gene="EMC3"
                     /locus_tag="YKL207W"
                     /gene_synonym="AIM27"
     mRNA            48194..48955
                     /gene="EMC3"
                     /locus_tag="YKL207W"
                     /gene_synonym="AIM27"
                     /product="Emc3p"
     CDS             48194..48955
                     /gene="EMC3"
                     /locus_tag="YKL207W"
                     /gene_synonym="AIM27"
                     /experiment="EXISTENCE:direct assay:GO:0072546 EMC complex
                     [PMID:19325107]"
                     /experiment="EXISTENCE:genetic interaction:GO:0034975
                     protein folding in endoplasmic reticulum [PMID:19325107]"
                     /note="Member of conserved ER transmembrane complex;
                     required for efficient folding of proteins in the ER;
                     required for respiratory growth; null mutant displays
                     induction of the unfolded protein response; homologous to
                     worm Y62E10A.10/EMC-3, fly CG6750, human TMEM111"
                     /codon_start=1
                     /product="Emc3p"
                     /protein_id="DAA08962.1"
                     /db_xref="SGD:S000001690"
                     /translation="MLLDDQLKYWVLLPISIVMVLTGVLKQYIMTLITGSSANEAQPR
                     VKLTEWQYLQWAQLLIGNGGNLSSDAFAAKKEFLVKDLTEERHLAKAKQQDGSQAGEV
                     PNPFNDPSMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAKFKEML
                     QTGIICQDLDVRWVSSISWYFISVLGLNPVYNLIGLNDQDMGIQAGIGGPQGPQGPPQ
                     SQVDKAMHAMANDLTIIQHETCLDNVEQRVLKQYM"
     gene            complement(49006..49809)
                     /gene="ADD66"
                     /locus_tag="YKL206C"
                     /gene_synonym="PBA2"
                     /gene_synonym="POC2"
     mRNA            complement(49006..49809)
                     /gene="ADD66"
                     /locus_tag="YKL206C"
                     /gene_synonym="PBA2"
                     /gene_synonym="POC2"
                     /product="Add66p"
     CDS             complement(49006..49809)
                     /gene="ADD66"
                     /locus_tag="YKL206C"
                     /gene_synonym="PBA2"
                     /gene_synonym="POC2"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:17634286]"
                     /experiment="EXISTENCE:genetic interaction:GO:0043248
                     proteasome assembly [PMID:17431397]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0043248
                     proteasome assembly [PMID:17634286]"
                     /note="Protein involved in 20S proteasome assembly; forms
                     a heterodimer with Pba1p that binds to proteasome
                     precursors; interaction with Pba1p-Add66p may affect
                     function of the mature proteasome and its role in
                     maintaining respiratory metabolism; similar to human PAC2
                     constituent of the PAC1-PAC2 complex involved in
                     proteasome assembly"
                     /codon_start=1
                     /product="Add66p"
                     /protein_id="DAA08963.1"
                     /db_xref="SGD:S000001689"
                     /translation="MSCLVLPLVSVGNIPQLSIDWLLNSQANEWEYLEALDSKYLVEF
                     VGPLDRPEDGSDSLYKDADMKYSSALEVFYNKKRGLFAIQQRTPLVSVNYLNNFIVEI
                     ILPFLSKYNISEICIWDSLYAMEDENGVIVRPQEVYSLGEFYFDDEAELLSNLHLNDQ
                     ESMVNNWLHFTPTSFQDKISVDQPIFKILFQILNASQRPKALRSIKYCSCLANEGDNS
                     LDSQQFLQWIISQKVIKNAPPIVKFVRPISWQGAYGMADARDKFVDLYN"
     gene            50051..53353
                     /gene="LOS1"
                     /locus_tag="YKL205W"
     mRNA            50051..53353
                     /gene="LOS1"
                     /locus_tag="YKL205W"
                     /product="Ran GTPase-binding protein LOS1"
     CDS             50051..53353
                     /gene="LOS1"
                     /locus_tag="YKL205W"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:18045534]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0016363 nuclear
                     matrix [PMID:8366091]"
                     /experiment="EXISTENCE:direct assay:GO:0031267 small
                     GTPase binding [PMID:9774653]"
                     /experiment="EXISTENCE:genetic interaction:GO:0071528 tRNA
                     re-export from nucleus [PMID:20032305]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006409 tRNA
                     export from nucleus [PMID:9802895]"
                     /note="Nuclear pore protein; involved in nuclear export of
                     pre-tRNA and in re-export of mature tRNAs after their
                     retrograde import from the cytoplasm; deletion mutation
                     extends replicative lifespan, as does exclusion of Los1p
                     from the nucleus in response to caloric restriction"
                     /codon_start=1
                     /product="Ran GTPase-binding protein LOS1"
                     /protein_id="DAA08964.1"
                     /db_xref="SGD:S000001688"
                     /translation="MLERIQQLVNAVNDPRSDVATKRQAIELLNGIKSSENALEIFIS
                     LVINENSNDLLKFYGLSTLIELMTEGVNANPNGLNLVKFEITKWLKFQVLGNKQTKLP
                     DFLMNKISEVLTTLFMLMYSDCNGNQWNSFFDDLMSLFQVDSAISNTSPSTDGNILLG
                     LEFFNKLCLMINSEIADQSFIRSKESQLKNNNIKDWMRDNDIMKLSNVWFQCLKLDEQ
                     IVSQCPGLINSTLDCIGSFISWIDINLIIDANNYYLQLIYKFLNLKETKISCYNCILA
                     IISKKMKPMDKLAFLNMINLTNELTYYHQAISMNPQIITFDNLEVWESLTKLITSFGI
                     EFTIIIEQVNDDQKLDTLYKQSVISNVDSILLEKIIPILLEFMNNEFDSITAKTFPFW
                     SNYLAFLKKYKASSPNFVPLHKDFLDNFQQICFKRMKFSDDEVTQDDFEEFNETVRFK
                     LKNFQEIIVVIDPSLFLNNISQEISANLMNCKNESWQIFELTIYQIFNLSECTKNNYF
                     GLNKNEIMTSQPSLTLVRFLNELLMMKDFLLAIDNEQIQILFMELIVKNYNFIFSTSA
                     NTANATDDDEKYLLILNIFMSSFAMFNKRENVRLRSWYLFTRFLKLTRINLKKILFAN
                     KNLVNEITNKISPLLHIKVTSINAQGTDDNDTIFDNQLYIFEGIGFIITLNNSSQELT
                     AATANTPIDYDILDQILTPLFTQLEGCITQGASPVVILECHHILMAIGTLARGLHIGL
                     VPENQVNNMVVNKKLINDSLIHKFSNIAEVILVTFSFFNKFENIRDASRFTFARLIPI
                     LSNKILPFINKLIELILSSTDLKSWEMIDFLGFLSQLIHMFHTDTDCYQLFNQLLTPL
                     INKVHSIIEEIDEQHDQQSSSNKPIDTAVTATSVNKNIVVTDSYRDKILLKKAYCTFL
                     QSFTNNSVTSILLSDINRAILPVILNDLVTYTPQEIQETSMMKVSLNVLCNFIKCFGN
                     GTCLDNDDINKDPNLKIDGLNEYFIMKCVPIIFEIPFNPIYKFNIKEGNFKTMAYDLA
                     RLLRELFIVSSNPTTNENECVKYLTQIYLPQIQLPQELTIQLVNMLTTMGQKQFEKWF
                     VDNFISVLKQGQ"
     gene            53704..55602
                     /gene="EAP1"
                     /locus_tag="YKL204W"
     mRNA            53704..55602
                     /gene="EAP1"
                     /locus_tag="YKL204W"
                     /product="Eap1p"
     CDS             53704..55602
                     /gene="EAP1"
                     /locus_tag="YKL204W"
                     /experiment="EXISTENCE:direct assay:GO:0003729 mRNA
                     binding [PMID:23222640]"
                     /experiment="EXISTENCE:direct assay:GO:0005844 polysome
                     [PMID:22890846]"
                     /experiment="EXISTENCE:direct assay:GO:0008190 eukaryotic
                     initiation factor 4E binding [PMID:10848587]"
                     /experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
                     stress granule [PMID:18981231|PMID:26777405]"
                     /experiment="EXISTENCE:direct assay:GO:0017148 negative
                     regulation of translation [PMID:10848587]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000290
                     deadenylation-dependent decapping of nuclear-transcribed
                     mRNA [PMID:22890846]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006402 mRNA
                     catabolic process [PMID:22890846]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0017148
                     negative regulation of translation [PMID:10848587]"
                     /note="eIF4E-associated protein, competes with eIF4G for
                     binding to eIF4E; accelerates mRNA degradation by
                     promoting decapping, facilitated by interaction with
                     eIF4E; essential for Puf5p mediated repression; associates
                     with Puf5p and Dhh1p; inhibits cap-dependent translation;
                     functions independently of eIF4E to maintain genetic
                     stability; plays a role in cell growth, implicated in the
                     TOR signaling cascade"
                     /codon_start=1
                     /product="Eap1p"
                     /protein_id="DAA08965.1"
                     /db_xref="SGD:S000001687"
                     /translation="MELNDPSIISSSQFSGELSDSDTAAATHKSQQAISNLFQKLAKK
                     GREEKPIGSVESSTDSSNISVATSGNNKESNKKKNKKTAMLNFSSLTDPITNYKPMDL
                     QYKTYAYSMNELYHLKPSLASASYEEDPLISELVRSLPKRKFWRLRMGPPDQKHANNH
                     HFNGNNGGGSWKAGYKNGKNDERRMSRTKNMQGGKRRSQQDDEEKKIDQEMLEMDKNL
                     QLGGDVGHSIADFEDWKAKMKELELKKLSKSKGISNSTAIAPRESASHETPTDLRPVI
                     PRGPSSITDFLNLKRQDKKEESSQQTPGIPVGQPSLSKTSIEQVNELETNSDLGKSSS
                     SRFSSFFNKSATSLPSLDNNNQVPSSNVSVVNNDGNSTPHQSGSRLMSFFKESRSSTP
                     NAESQLLSASDKDNGKMQTLPQFQQQPQQMQPMAFTQHPPNNNAFFNGLLNKGKSETS
                     TPPPPPPGLIAHQGPQFPVMGVPPNFPQRMMPPPPGLVQFQKDSKDVNKKEDRQLRQN
                     KNPNGTRNSKGKQEETATPDLPQQQYMPPPPPPGFFPMHPNFPNGPMPPLPQGFPIPP
                     NGMLPVTGQQPQPPYPNMMLQGNFPPNFQQGFGSNSPMPIPSIINANGKNVTNQLPPG
                     LNSKKNIK"
     rep_origin      55671..55917
                     /note="ARS1103; Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118401"
     gene            complement(55935..63359)
                     /gene="TOR2"
                     /locus_tag="YKL203C"
                     /gene_synonym="DRR2"
     mRNA            complement(55935..63359)
                     /gene="TOR2"
                     /locus_tag="YKL203C"
                     /gene_synonym="DRR2"
                     /product="phosphatidylinositol kinase-related protein
                     kinase TOR2"
     CDS             complement(55935..63359)
                     /gene="TOR2"
                     /locus_tag="YKL203C"
                     /gene_synonym="DRR2"
                     /EC_number="2.7.1.67"
                     /EC_number="2.7.11.1"
                     /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
                     vacuole membrane [PMID:8846782]"
                     /experiment="EXISTENCE:direct assay:GO:0004674 protein
                     serine/threonine kinase activity
                     [PMID:16055732|PMID:22307609]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0005886 plasma
                     membrane [PMID:10973982]"
                     /experiment="EXISTENCE:direct assay:GO:0006468 protein
                     phosphorylation [PMID:16055732|PMID:22307609]"
                     /experiment="EXISTENCE:direct assay:GO:0031234 extrinsic
                     component of cytoplasmic side of plasma membrane
                     [PMID:12631735|PMID:18723607]"
                     /experiment="EXISTENCE:genetic interaction:GO:0010507
                     negative regulation of autophagy [PMID:9461583]"
                     /experiment="EXISTENCE:genetic interaction:GO:0035025
                     positive regulation of Rho protein signal transduction
                     [PMID:9038344]"
                     /experiment="EXISTENCE:genetic interaction:GO:2001108
                     positive regulation of Rho guanyl-nucleotide exchange
                     factor activity [PMID:9038344]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004674 protein
                     serine/threonine kinase activity [PMID:16055732]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006468 protein
                     phosphorylation [PMID:16055732]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007010
                     cytoskeleton organization [PMID:9475724]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030950
                     establishment or maintenance of actin cytoskeleton
                     polarity [PMID:12408816]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031929 TOR
                     signaling [PMID:12719473|PMID:8186460]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0035025
                     positive regulation of Rho protein signal transduction
                     [PMID:9038344]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042254
                     ribosome biogenesis [PMID:10198052]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045807
                     positive regulation of endocytosis [PMID:14593073]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1905356
                     regulation of snRNA pseudouridine synthesis
                     [PMID:27268497]"
                     /experiment="EXISTENCE:mutant phenotype:GO:2001108
                     positive regulation of Rho guanyl-nucleotide exchange
                     factor activity [PMID:9038344]"
                     /experiment="EXISTENCE:physical interaction:GO:0005515
                     protein binding [PMID:12631735]"
                     /experiment="EXISTENCE:physical interaction:GO:0031931
                     TORC1 complex [PMID:12408816]"
                     /experiment="EXISTENCE:physical interaction:GO:0031932
                     TORC2 complex [PMID:12408816]"
                     /note="PIK-related protein kinase and rapamycin target;
                     subunit of TORC1, a complex that regulates growth in
                     response to nutrients and TORC2, a complex that regulates
                     cell-cycle dependent polarization of the actin
                     cytoskeleton; involved in meiosis; TOR2 has a paralog,
                     TOR1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="phosphatidylinositol kinase-related protein
                     kinase TOR2"
                     /protein_id="DAA08966.1"
                     /db_xref="SGD:S000001686"
                     /translation="MNKYINKYTTPPNLLSLRQRAEGKHRTRKKLTHKSHSHDDEMST
                     TSNTDSNHNGPNDSGRVITGSAGHIGKISFVDSELDTTFSTLNLIFDKLKSDVPQERA
                     SGANELSTTLTSLAREVSAEQFQRFSNSLNNKIFELIHGFTSSEKIGGILAVDTLISF
                     YLSTEELPNQTSRLANYLRVLIPSSDIEVMRLAANTLGRLTVPGGTLTSDFVEFEVRT
                     CIDWLTLTADNNSSSSKLEYRRHAALLIIKALADNSPYLLYPYVNSILDNIWVPLRDA
                     KLIIRLDAAVALGKCLTIIQDRDPALGKQWFQRLFQGCTHGLSLNTNDSVHATLLVFR
                     ELLSLKAPYLRDKYDDIYKSTMKYKEYKFDVIRREVYAILPLLAAFDPAIFTKKYLDR
                     IMVHYLRYLKNIDMNAANNSDKPFILVSIGDIAFEVGSSISPYMTLILDNIREGLRTK
                     FKVRKQFEKDLFYCIGKLACALGPAFAKHLNKDLLNLMLNCPMSDHMQETLMILNEKI
                     PSLESTVNSRILNLLSISLSGEKFIQSNQYDFNNQFSIEKARKSRNQSFMKKTGESND
                     DITDAQILIQCFKMLQLIHHQYSLTEFVRLITISYIEHEDSSVRKLAALTSCDLFIKD
                     DICKQTSVHALHSVSEVLSKLLMIAITDPVAEIRLEILQHLGSNFDPQLAQPDNLRLL
                     FMALNDEIFGIQLEAIKIIGRLSSVNPAYVVPSLRKTLLELLTQLKFSNMPKKKEESA
                     TLLCTLINSSDEVAKPYIDPILDVILPKCQDASSAVASTALKVLGELSVVGGKEMTRY
                     LKELMPLIINTFQDQSNSFKRDAALTTLGQLAASSGYVVGPLLDYPELLGILINILKT
                     ENNPHIRRGTVRLIGILGALDPYKHREIEVTSNSKSSVEQNAPSIDIALLMQGVSPSN
                     DEYYPTVVIHNLMKILNDPSLSIHHTAAIQAIMHIFQNLGLRCVSFLDQIIPGIILVM
                     RSCPPSQLDFYFQQLGSLISIVKQHIRPHVEKIYGVIREFFPIIKLQITIISVIESIS
                     KALEGEFKRFVPETLTFFLDILENDQSNKRIVPIRILKSLVTFGPNLEDYSHLIMPIV
                     VRMTEYSAGSLKKISIITLGRLAKNINLSEMSSRIVQALVRILNNGDRELTKATMNTL
                     SLLLLQLGTDFVVFVPVINKALLRNRIQHSVYDQLVNKLLNNECLPTNIIFDKENEVP
                     ERKNYEDEMQVTKLPVNQNILKNAWYCSQQKTKEDWQEWIRRLSIQLLKESPSACLRS
                     CSSLVSVYYPLARELFNASFSSCWVELQTSYQEDLIQALCKALSSSENPPEIYQMLLN
                     LVEFMEHDDKPLPIPIHTLGKYAQKCHAFAKALHYKEVEFLEEPKNSTIEALISINNQ
                     LHQTDSAIGILKHAQQHNELQLKETWYEKLQRWEDALAAYNEKEAAGEDSVEVMMGKL
                     RSLYALGEWEELSKLASEKWGTAKPEVKKAMAPLAAGAAWGLEQWDEIAQYTSVMKSQ
                     SPDKEFYDAILCLHRNNFKKAEVHIFNARDLLVTELSALVNESYNRAYNVVVRAQIIA
                     ELEEIIKYKKLPQNSDKRLTMRETWNTRLLGCQKNIDVWQRILRVRSLVIKPKEDAQV
                     RIKFANLCRKSGRMALAKKVLNTLLEETDDPDHPNTAKASPPVVYAQLKYLWATGLQD
                     EALKQLINFTSRMAHDLGLDPNNMIAQSVPQQSKRVPRHVEDYTKLLARCFLKQGEWR
                     VCLQPKWRLSNPDSILGSYLLATHFDNTWYKAWHNWALANFEVISMLTSVSKKKQEGS
                     DASSVTDINEFDNGMIGVNTFDAKEVHYSSNLIHRHVIPAIKGFFHSISLSESSSLQD
                     ALRLLTLWFTFGGIPEATQAMHEGFNLIQIGTWLEVLPQLISRIHQPNQIVSRSLLSL
                     LSDLGKAHPQALVYPLMVAIKSESLSRQKAALSIIEKMRIHSPVLVDQAELVSHELIR
                     MAVLWHEQWYEGLDDASRQFFGEHNTEKMFAALEPLYEMLKRGPETLREISFQNSFGR
                     DLNDAYEWLMNYKKSKDVSNLNQAWDIYYNVFRKIGKQLPQLQTLELQHVSPKLLSAH
                     DLELAVPGTRASGGKPIVKISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHED
                     IRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVL
                     IREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKS
                     RSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAA
                     ILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAF
                     DPLINWGFDLPTKKIEEETGIQLPVMNANELLSNGAITEEEVQRVENEHKNAIRNARA
                     MLVLKRITDKLTGNDIRRFNDLDVPEQVDKLIQQATSVENLCQHYIGWCPFW"
     gene            complement(63930..67466)
                     /gene="MNN4"
                     /locus_tag="YKL201C"
                     /gene_synonym="YKL200C"
     mRNA            complement(63930..67466)
                     /gene="MNN4"
                     /locus_tag="YKL201C"
                     /gene_synonym="YKL200C"
                     /product="Mnn4p"
     CDS             complement(63930..67466)
                     /gene="MNN4"
                     /locus_tag="YKL201C"
                     /gene_synonym="YKL200C"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006487 protein
                     N-linked glycosylation [PMID:9023541]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006493 protein
                     O-linked glycosylation [PMID:9813355]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0008047 enzyme
                     activator activity [PMID:9459307]"
                     /note="Putative positive regulator of mannosylphosphate
                     transferase Mnn6p; involved in mannosylphosphorylation of
                     N-linked oligosaccharides; expression increases in
                     late-logarithmic and stationary growth phases; coding
                     sequence contains length polymorphisms in different
                     strains; MNN4 has a paralog, YJR061W, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Mnn4p"
                     /protein_id="DAA08967.1"
                     /db_xref="SGD:S000001684"
                     /translation="MLQRISSKLHRRFLSGLLRVKHYPLRRILLPLILLQIIIITFIW
                     SNSPQRNGLGRDADYLLPNYNELDSDDDSWYSILTSSFKNDRKIQFAKTLYENLKFGT
                     NPKWVNEYTLQNDLLSVKMGPRKGSKLESVDELKFYDFDPRLTWSVVLNHLQNNDADQ
                     PEKLPFSWYDWTTFHELNKLISIDKTVLPCNFLFQSAFDKESLEAIETELGEPLFLYE
                     RPKYAQKLWYKAARNQDRIKDSKELKKHCSKLFTPDGHGSPKGLRFNTQFQIKELYDK
                     VRPEVYQLQARNYILTTQSHPLSISIIESDNSTYQVPLQTEKSKNLVQSGLLQEYIND
                     NINSTNKRKKNKQDVEFNHNRLFQEFVNNDQVNSLYKLEIEETDKFTFDKDLVYLSPS
                     DFKFDASKKIEELEEQKKLYPDKFSAHNENYLNSLKNSVKTSPALQRKFFYEAGAVKQ
                     YKGMGFHRDKRFFNVDTLINDKQEYQARLNSMIRTFQKFTKANGIISWLSHGTLYGYL
                     YNGMAFPWDNDFDLQMPIKHLQLLSQYFNQSLILEDPRQGNGRYFLDVSDSLTVRING
                     NGKNNIDARFIDVDTGLYIDITGLASTSAPSRDYLNSYIEERLQEEHLDINNIPESNG
                     ETATLPDKVDDGLVNMATLNITELRDYITSDENKNHKRVPTDTDLKDLLKKELEELPK
                     SKTIENKLNPKQRYFLNEKLKLYNCRNNHFNSFEELSPLINTVFHGVPALIPHRHTYC
                     LHNEYHVPDRYAFDAYKNTAYLPEFRFWFDYDGLKKCSNINSWYPNIPSINSWNPNLL
                     KEISSTKFESKLFDSNKVSEYSFKNLSMDDVRLIYKNIPKAGFIEVFTNLYNSFNVTA
                     YRQKELEIQYCQNLTFIEKKKLLHQLRINVAPKLSSPAKDPFLFGYEKAMWKDLSKSM
                     NQTTLDQVTKIVHEEYVGKIIDLSESLKYRNFSLFNITFDETGTTLDDNTEDYTPANT
                     VEVNPVDFKSNLNFSSNSFLDLNSYGLDLFAPTLSDVNRKGIQMFDKDPIIVYEDYAY
                     AKLLEERKRREKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEE
                     EKKKQEEEEKKKKEEEEKKKQEEGEKMKNEDEENKKNEDEEKKKNEEEEKKKQEEKNK
                     KNEDEEKKKQEEEEKKKNEEEEKKKQEEGHSN"
     gene            complement(68232..70220)
                     /gene="PTK1"
                     /locus_tag="YKL198C"
                     /gene_synonym="KKT8"
                     /gene_synonym="POT1"
                     /gene_synonym="STK1"
                     /gene_synonym="YKL199C"
                     /gene_synonym="YKT9"
     mRNA            complement(68232..70220)
                     /gene="PTK1"
                     /locus_tag="YKL198C"
                     /gene_synonym="KKT8"
                     /gene_synonym="POT1"
                     /gene_synonym="STK1"
                     /gene_synonym="YKL199C"
                     /gene_synonym="YKT9"
                     /product="putative serine/threonine protein kinase PTK1"
     CDS             complement(68232..70220)
                     /gene="PTK1"
                     /locus_tag="YKL198C"
                     /gene_synonym="KKT8"
                     /gene_synonym="POT1"
                     /gene_synonym="STK1"
                     /gene_synonym="YKL199C"
                     /gene_synonym="YKT9"
                     /EC_number="2.7.11.1"
                     /experiment="EXISTENCE:genetic interaction:GO:0000296
                     spermine transport [PMID:7488221]"
                     /note="Putative serine/threonine protein kinase; regulates
                     spermine uptake; involved in polyamine transport; possible
                     mitochondrial protein; PTK1 has a paralog, PTK2, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="putative serine/threonine protein kinase PTK1"
                     /protein_id="DAA08968.2"
                     /db_xref="SGD:S000001681"
                     /translation="MTVSHNHSTKISQQPISSVSAFKFFGKKLLSSSHGNKLKKKASL
                     PPDFHSTSTNDSESSSPKLPNSLKTSRRANSFAHTTNSKRSLSSASTKILPPAGSSTS
                     ISRGNRHSSTSRNLSNSKFSSERLVYNPYGVSTPSTSLSSVSTSMKKDPDLGFYLHDG
                     DSKIRMLPIPIVDPNEYLPDEMKEASIQLSDNFVFDDENKTIGWGGSCEVRKIRSKYR
                     KKDVFALKKLNMIYNETPEKFYKRCSKEFIIAKQLSHHVHITNTFLLVKVPTTVYTTR
                     GWGFVMELGLRDLFAMIQKSGWRSVALAEKFCIFKQVACGVKFCHDQGIAHRDLKPEN
                     VLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPPEVMFYDSKKHYD
                     TELQQPYDPRALDCYGLGIILMTLVNNVIPFLESCSFDTGFRDYCDAYENFIRLHDRA
                     FRNRGNYRPGPGMEYHLARNFKNGHASRVAWRLADPEAATRYTIDDLFEDPWFQGIET
                     CVDANDKYVCKKPIIKTTTYENPRGFHIATDVAATTPTSNPFLKNRVPIRSMVDIAAH
                     PSPTATVLASSPPPPPPATHVPAEALFTLRETPPPQLATLTLSEEPPATPAPSAPSAP
                     SARVRGHSPHRVVHHHLNIVNSLVHSSSAASSQVPAST"
     gene            complement(70734..73865)
                     /gene="PEX1"
                     /locus_tag="YKL197C"
                     /gene_synonym="PAS1"
     mRNA            complement(70734..73865)
                     /gene="PEX1"
                     /locus_tag="YKL197C"
                     /gene_synonym="PAS1"
                     /product="AAA family ATPase peroxin 1"
     CDS             complement(70734..73865)
                     /gene="PEX1"
                     /locus_tag="YKL197C"
                     /gene_synonym="PAS1"
                     /experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005778 peroxisomal
                     membrane [PMID:16911527]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0016562 protein
                     import into peroxisome matrix, receptor recycling
                     [PMID:16007078]"
                     /experiment="EXISTENCE:direct assay:GO:0043335 protein
                     unfolding [PMID:29321502]"
                     /experiment="EXISTENCE:genetic interaction:GO:0016562
                     protein import into peroxisome matrix, receptor recycling
                     [PMID:16007078]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016562 protein
                     import into peroxisome matrix, receptor recycling
                     [PMID:16007078]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016887 ATPase
                     [PMID:15634331]"
                     /note="AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p
                     and participates in the recycling of peroxisomal signal
                     receptor Pex5p from the peroxisomal membrane to the
                     cystosol; induced by oleic acid and upregulated during
                     anaerobiosis; mutations in human PEX1 can lead to severe
                     peroxisomal disorders and early death"
                     /codon_start=1
                     /product="AAA family ATPase peroxin 1"
                     /protein_id="DAA08969.1"
                     /db_xref="SGD:S000001680"
                     /translation="MTTTKRLKFENLRIQFSNAIVGNFLRLPHSIINVLESTNYAIQE
                     FGIAVHSHNSDIPIVHLGWDGHDSGSSENVVLINPVLATVYDLNQKSPLVDLYIQRYD
                     HTHLATEVYVTPETSDDWEIIDANAMRFQNGEILHQTRIVTPGETLICYLEGIVTKFK
                     IDRVEPSMKSARITDGSLVVVAPKVNKTRLVKAEYGHSNKTILKNGAIQLLKKVILRS
                     TVCKMDFPKDNLFVVYISDGAQLPSQKGYASIVKCSLRQSKKSDSDNKSVGIPSKKIG
                     VFIKCDSQIPENHIALSSHLWDAFFTHPMNGAKIKLEFLQMNQANIISGRNATVNIKY
                     FGKDVPTKSGDQYSKLLGGSLLTNNLILPTEQIIIEIKKGESEQQLCNLNEISNESVQ
                     WKVTQMGKEEVKDIIERHLPKHYHVKETGEVSRTSKDEDDFITVNSIKKEMVNYLTSP
                     IIATPAIILDGKQGIGKTRLLKELINEVEKDHHIFVKYADCETLHETSNLDKTQKLIM
                     EWCSFCYWYGPSLIVLDNVEALFGKPQANDGDPSNNGQWDNASKLLNFFINQVTKIFN
                     KDNKRIRVLFSGKQKTQINPLLFDKHFVSETWSLRAPDKHARAKLLEYFFSKNQIMKL
                     NRDLQFSDLSLETEGFSPLDLEIFTEKIFYDLQLERDCDNVVTRELFSKSLSAFTPSA
                     LRGVKLTKETNIKWGDIGALANAKDVLLETLEWPTKYEPIFVNCPLRLRSGILLYGYP
                     GCGKTLLASAVAQQCGLNFISVKGPEILNKFIGASEQNIRELFERAQSVKPCILFFDE
                     FDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLDGVYILAATSRPDLIDSALLRPGRL
                     DKSVICNIPTESERLDILQAIVNSKDKDTGQKKFALEKNADLKLIAEKTAGFSGADLQ
                     GLCYNAYLKSVHRWLSAADQSEVVPGNDNIEYFSINEHGRREENRLRLKTLLQQDVVH
                     ETKTSTSAASELTAVVTINDLLEACQETKPSISTSELVKLRGIYDRFQKDRNGEMPNG
                     ENSIDIGSRLSLM"
     repeat_region   74236..74518
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000007055"
     gene            74624..74697
                     /locus_tag="YNCK0003W"
     tRNA            74624..74697
                     /locus_tag="YNCK0003W"
                     /product="tRNA-Asn"
                     /experiment="EXISTENCE:curator inference:GO:0005829
                     cytosol [PMID:9023104]"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /note="Asparagine tRNA (tRNA-Asn), predicted by
                     tRNAscan-SE analysis"
                     /db_xref="SGD:S000006671"
     gene            complement(74932..75534)
                     /gene="YKT6"
                     /locus_tag="YKL196C"
     mRNA            complement(74932..75534)
                     /gene="YKT6"
                     /locus_tag="YKL196C"
                     /product="palmitoyltransferase YKT6"
     CDS             complement(74932..75534)
                     /gene="YKT6"
                     /locus_tag="YKL196C"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:15723044]"
                     /experiment="EXISTENCE:direct assay:GO:0005484 SNAP
                     receptor activity [PMID:11959998]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005768 endosome
                     [PMID:18541004]"
                     /experiment="EXISTENCE:direct assay:GO:0005794 Golgi
                     apparatus [PMID:18541004]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0006906 vesicle
                     fusion [PMID:11959998]"
                     /experiment="EXISTENCE:direct assay:GO:0016020 membrane
                     [PMID:9211930]"
                     /experiment="EXISTENCE:direct assay:GO:0016409
                     palmitoyltransferase activity [PMID:14685280]"
                     /experiment="EXISTENCE:direct assay:GO:0031201 SNARE
                     complex [PMID:11959998]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006888
                     endoplasmic reticulum to Golgi vesicle-mediated transport
                     [PMID:9211930]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006891
                     intra-Golgi vesicle-mediated transport [PMID:10591633]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042144 vacuole
                     fusion, non-autophagic [PMID:10385523]"
                     /note="Vesicle membrane protein (v-SNARE) with
                     acyltransferase activity; involved in trafficking to and
                     within the Golgi, endocytic trafficking to the vacuole,
                     and vacuolar fusion; membrane localization due to
                     prenylation at the carboxy-terminus; human homolog YKT6
                     can complement yeast ykt6 mutant"
                     /codon_start=1
                     /product="palmitoyltransferase YKT6"
                     /protein_id="DAA08970.1"
                     /db_xref="SGD:S000001679"
                     /translation="MRIYYIGVFRSGGEKALELSEVKDLSQFGFFERSSVGQFMTFFA
                     ETVASRTGAGQRQSIEEGNYIGHVYARSEGICGVLITDKEYPVRPAYTLLNKILDEYL
                     VAHPKEEWADVTETNDALKMKQLDTYISKYQDPSQADAIMKVQQELDETKIVLHKTIE
                     NVLQRGEKLDNLVDKSESLTASSKMFYKQAKKSNSCCIIM"
     gene            75821..77032
                     /gene="MIA40"
                     /locus_tag="YKL195W"
                     /gene_synonym="FMP15"
                     /gene_synonym="TIM40"
     mRNA            75821..77032
                     /gene="MIA40"
                     /locus_tag="YKL195W"
                     /gene_synonym="FMP15"
                     /gene_synonym="TIM40"
                     /product="Mia40p"
     CDS             75821..77032
                     /gene="MIA40"
                     /locus_tag="YKL195W"
                     /gene_synonym="FMP15"
                     /gene_synonym="TIM40"
                     /experiment="EXISTENCE:direct assay:GO:0003756 protein
                     disulfide isomerase activity [PMID:25451030]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion
                     [PMID:14562095|PMID:14576278|PMID:14690591|PMID:16823961|P
                     MID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005758
                     mitochondrial intermembrane space [PMID:15359280]"
                     /experiment="EXISTENCE:direct assay:GO:0006457 protein
                     folding [PMID:22990235|PMID:25451030]"
                     /experiment="EXISTENCE:direct assay:GO:0016972 thiol
                     oxidase activity [PMID:25451030]"
                     /experiment="EXISTENCE:direct assay:GO:0031305 integral
                     component of mitochondrial inner membrane
                     [PMID:15364952|PMID:15620710]"
                     /experiment="EXISTENCE:direct assay:GO:0051537 2 iron, 2
                     sulfur cluster binding [PMID:23834247]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016491
                     oxidoreductase activity [PMID:22990235]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045041 protein
                     import into mitochondrial intermembrane space
                     [PMID:15359280|PMID:15364952|PMID:17336303|PMID:27343349]"
                     /experiment="EXISTENCE:physical interaction:GO:0045041
                     protein import into mitochondrial intermembrane space
                     [PMID:15989955]"
                     /note="Import and assembly protein in mitochondrial
                     intermembrane space; component of MIA pathway which
                     mediates import and oxidative folding of substrates
                     including small proteins containing twin cysteine motifs;
                     acts in concert with Erv1p, which oxidizes the cysteine
                     residues of Mia40p to comprise a disulfide relay system
                     that catalyzes import; also mediates folding of Atp23p via
                     a chaperone-like activity; forms a dimer that binds
                     iron-sulfur cluster in vitro"
                     /codon_start=1
                     /product="Mia40p"
                     /protein_id="DAA08971.1"
                     /db_xref="SGD:S000001678"
                     /translation="MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQ
                     EKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNN
                     SKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDES
                     KVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEK
                     SQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTE
                     EEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKF
                     QHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDV
                     KKEPLNEESKP"
     gene            complement(77258..78646)
                     /gene="MST1"
                     /locus_tag="YKL194C"
     mRNA            complement(77258..78646)
                     /gene="MST1"
                     /locus_tag="YKL194C"
                     /product="threonine--tRNA ligase MST1"
     CDS             complement(77258..78646)
                     /gene="MST1"
                     /locus_tag="YKL194C"
                     /EC_number="6.1.1.3"
                     /experiment="EXISTENCE:direct assay:GO:0004829
                     threonine-tRNA ligase activity [PMID:21321019]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion
                     [PMID:2999113|PMID:14576278|PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0070159
                     mitochondrial threonyl-tRNA aminoacylation
                     [PMID:21321019]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004829
                     threonine-tRNA ligase activity [PMID:2999113]"
                     /note="Mitochondrial threonyl-tRNA synthetase;
                     aminoacylates both the canonical threonine tRNA tT(UGU)Q1
                     and the unusual threonine tRNA tT(UAG)Q2 in vitro; lacks a
                     typical editing domain, but has pre-transfer editing
                     activity stimulated by the unusual tRNA-Thr"
                     /codon_start=1
                     /product="threonine--tRNA ligase MST1"
                     /protein_id="DAA08972.1"
                     /db_xref="SGD:S000001677"
                     /translation="MKIQLVRWHCSRNALWNRAFYSTRKATKNASSATPATMTSMVSQ
                     RQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEK
                     SGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPL
                     HRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGS
                     GAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDI
                     MVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI
                     DSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHF
                     NVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQI
                     WEKFIELEKNYK"
     gene            complement(78866..79882)
                     /gene="SDS22"
                     /locus_tag="YKL193C"
                     /gene_synonym="EGP1"
     mRNA            complement(78866..79882)
                     /gene="SDS22"
                     /locus_tag="YKL193C"
                     /gene_synonym="EGP1"
                     /product="type 1 protein phosphatase-activating protein
                     SDS22"
     CDS             complement(78866..79882)
                     /gene="SDS22"
                     /locus_tag="YKL193C"
                     /gene_synonym="EGP1"
                     /experiment="EXISTENCE:direct assay:GO:0000164 protein
                     phosphatase type 1 complex [PMID:10775415]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:11801737|PMID:11914276|PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:11914276|PMID:14562095]"
                     /experiment="EXISTENCE:genetic interaction:GO:0004865
                     protein serine/threonine phosphatase inhibitor activity
                     [PMID:17142459]"
                     /experiment="EXISTENCE:genetic interaction:GO:0072542
                     protein phosphatase activator activity
                     [PMID:11801737|PMID:18172024]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004865 protein
                     serine/threonine phosphatase inhibitor activity
                     [PMID:17142459]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007059
                     chromosome segregation [PMID:11801737]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051457
                     maintenance of protein location in nucleus
                     [PMID:11801737]"
                     /note="Regulatory subunit of the type 1 protein
                     phosphatase (PP1) Glc7p; whether it functions as a
                     positive or negative regulator of Glc7p is controversial;
                     involved in the regulation of Glc7p nuclear localization
                     and function"
                     /codon_start=1
                     /product="type 1 protein phosphatase-activating protein
                     SDS22"
                     /protein_id="DAA08973.1"
                     /db_xref="SGD:S000001676"
                     /translation="MDKNSVNKDSEEKDERHKIEVVDDTNPDFITADSELTQDLPDDV
                     EVIDLVHLKIKSLEDLNLYRFKNLKQLCLRQNLIESISEVEVLPHDKIVDLDFYDNKI
                     KHISSNVNKLTKLTSLDLSFNKIKHIKNLENLTDLENLYFVQNSISKIENLSTLKSLK
                     NLELGGNKVHSIEPDSFEGLSNLEEIWLGKNSIPRLINLHPLKNLKILSIQSNKLKKI
                     ENLEELTNLEELYLSHNFITKIEGLEKNLKLTTLDVTSNKITSLENLNHLSNLTDIWA
                     SFNKIDQSFESLGENLSALSRLETIYLEGNPIQLENKTSYRRKLTMNLPPSLQKIDAT
                     YIRG"
     gene            complement(80160..80537)
                     /gene="ACP1"
                     /locus_tag="YKL192C"
     mRNA            complement(80160..80537)
                     /gene="ACP1"
                     /locus_tag="YKL192C"
                     /product="acyl carrier protein"
     CDS             complement(80160..80537)
                     /gene="ACP1"
                     /locus_tag="YKL192C"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0009107 lipoate
                     biosynthetic process [PMID:9187370]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016226
                     iron-sulfur cluster assembly [PMID:27540631]"
                     /experiment="EXISTENCE:physical interaction:GO:0099128
                     mitochondrial iron-sulfur cluster assembly complex
                     [PMID:27540631]"
                     /note="Mitochondrial matrix acyl carrier protein; involved
                     in biosynthesis of octanoate, which is a precursor to
                     lipoic acid; coordinates mitochondrial fatty acid and iron
                     sulfur cluster metabolism; activated by
                     phosphopantetheinylation catalyzed by Ppt2p"
                     /codon_start=1
                     /product="acyl carrier protein"
                     /protein_id="DAA08974.1"
                     /db_xref="SGD:S000001675"
                     /translation="MFRSVCRISSRVAPSAYRTIMGRSVMSNTILAQRFYSANLSKDQ
                     VSQRVIDVIKAFDKNSPNIANKQISSDTQFHKDLGLDSLDTVELLVAIEEEFDIEIPD
                     KVADELRSVGETVDYIASNPDAN"
     gene            81035..82639
                     /gene="DPH2"
                     /locus_tag="YKL191W"
     mRNA            81035..82639
                     /gene="DPH2"
                     /locus_tag="YKL191W"
                     /product="2-(3-amino-3-carboxypropyl)histidine synthase"
     CDS             81035..82639
                     /gene="DPH2"
                     /locus_tag="YKL191W"
                     /EC_number="2.5.1.108"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0017183
                     peptidyl-diphthamide biosynthetic process from
                     peptidyl-histidine [PMID:15485916|PMID:8406038]"
                     /note="Protein required for synthesis of diphthamide;
                     required along with Dph1p, Kti11p, Jjj3p, and Dph5p;
                     diphthamide is a modified histidine residue of translation
                     elongation factor 2 (Eft1p or Eft2p); forms a complex with
                     Dph1p that catalyzes the first step of diphthamide
                     biosynthesis"
                     /codon_start=1
                     /product="2-(3-amino-3-carboxypropyl)histidine synthase"
                     /protein_id="DAA08975.1"
                     /db_xref="SGD:S000001674"
                     /translation="MEVAPALSTTQSDVAFQKVETHEIDRSSYLGPCYNSDELMQLIS
                     AYYNVEPLVGYLEQHPEYQNVTLQFPDDLIKDSSLIVRLLQSKFPHGKIKFWVLADTA
                     YSACCVDEVAAEHVHAEVVVHFGDACLNAIQNLPVVYSFGTPFLDLALVVENFQRAFP
                     DLSSKICLMANAPFSKHLSQLYNILKGDLHYTNIIYSQVNTSAVEEKFVTILDTFHVP
                     EDVDQVGVFEKNSVLFGQHDKADNISPEDYHLFHLTTPQDPRLLYLSTVFQSVHIFDP
                     ALPGMVTGPFPSLMRRYKYMHVARTAGCIGILVNTLSLRNTRETINELVKLIKTREKK
                     HYLFVVGKPNVAKLANFEDIDIWCILGCSQSGIIVDQFNEFYKPIITPYELNLALSEE
                     VTWTGKWVVDFRDAIDEIEQNLGGQDTISASTTSDEPEFDVVRGRYTSTSRPLRALTH
                     LELEAADDDDSKQLTTRHTASGAVIKGTVSTSASALQNRSWKGLGSDFDSTEVDNTGA
                     DIEEGISGVARGYGFDREDAMKKENK"
     gene            82947..83550
                     /gene="CNB1"
                     /locus_tag="YKL190W"
                     /gene_synonym="CRV1"
                     /gene_synonym="YCN2"
     mRNA            join(82947..82998,83075..83550)
                     /gene="CNB1"
                     /locus_tag="YKL190W"
                     /gene_synonym="CRV1"
                     /gene_synonym="YCN2"
                     /product="calcineurin regulatory subunit B"
     CDS             join(82947..82998,83075..83550)
                     /gene="CNB1"
                     /locus_tag="YKL190W"
                     /gene_synonym="CRV1"
                     /gene_synonym="YCN2"
                     /experiment="EXISTENCE:direct assay:GO:0004723
                     calcium-dependent protein serine/threonine phosphatase
                     activity [PMID:1321337]"
                     /experiment="EXISTENCE:direct assay:GO:0005509 calcium ion
                     binding [PMID:1321337]"
                     /experiment="EXISTENCE:direct assay:GO:0005955 calcineurin
                     complex [PMID:1321337]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000754
                     adaptation of signaling pathway by response to pheromone
                     involved in conjugation with cellular fusion
                     [PMID:1321337]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006873
                     cellular ion homeostasis [PMID:8798496]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031505
                     fungal-type cell wall organization [PMID:7530227]"
                     /note="Calcineurin B; regulatory subunit of calcineurin, a
                     Ca++/calmodulin-regulated type 2B protein phosphatase
                     which regulates Crz1p (stress-response transcription
                     factor); other calcineurin subunit encoded by CNA1 and/or
                     CMP1; regulates function of Aly1p alpha-arrestin;
                     myristoylation by Nmt1p reduces calcineurin activity in
                     response to submaximal Ca signals, is needed to prevent
                     constitutive phosphatase activity; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="calcineurin regulatory subunit B"
                     /protein_id="DAA08976.1"
                     /db_xref="SGD:S000001673"
                     /translation="MGAAPSKIVDGLLEDTNFDRDEIERLRKRFMKLDRDSSGSIDKN
                     EFMSIPGVSSNPLAGRIMEVFDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIY
                     DIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEFKNAI
                     ETTEVAKSLTLQYDV"
     repeat_region   complement(83808..84115)
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000007050"
     gene            84208..84291
                     /locus_tag="YNCK0004W"
     tRNA            84208..84291
                     /locus_tag="YNCK0004W"
                     /product="tRNA-Leu"
                     /experiment="EXISTENCE:curator inference:GO:0005829
                     cytosol [PMID:9023104]"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /experiment="EXISTENCE:direct assay:GO:0030371 translation
                     repressor activity [PMID:27609601]"
                     /experiment="EXISTENCE:direct assay:GO:0043022 ribosome
                     binding [PMID:27609601]"
                     /experiment="EXISTENCE:direct assay:GO:0043555 regulation
                     of translation in response to stress [PMID:27609601]"
                     /note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006651"
     gene            84704..85903
                     /gene="HYM1"
                     /locus_tag="YKL189W"
     mRNA            84704..85903
                     /gene="HYM1"
                     /locus_tag="YKL189W"
                     /product="Hym1p"
     CDS             84704..85903
                     /gene="HYM1"
                     /locus_tag="YKL189W"
                     /experiment="EXISTENCE:direct assay:GO:0000131 incipient
                     cellular bud site [PMID:12972564]"
                     /experiment="EXISTENCE:direct assay:GO:0005933 cellular
                     bud [PMID:12972564]"
                     /experiment="EXISTENCE:direct assay:GO:0043332 mating
                     projection tip [PMID:12972564]"
                     /experiment="EXISTENCE:genetic interaction:GO:0007118
                     budding cell apical bud growth [PMID:12972564]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000920 septum
                     digestion after cytokinesis [PMID:11259593]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006355
                     regulation of transcription, DNA-templated
                     [PMID:12972564]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007118 budding
                     cell apical bud growth [PMID:12972564]"
                     /note="Component of the RAM signaling network; is involved
                     in regulation of Ace2p activity and cellular
                     morphogenesis; interacts with Sog2p; allosterically
                     activates Kic1p; localizes to sites of polarized growth
                     during budding and during the mating response"
                     /codon_start=1
                     /product="Hym1p"
                     /protein_id="DAA08977.1"
                     /db_xref="SGD:S000001672"
                     /translation="MFKKYKNQDLDMAFWWKKNPKTPSDYARLIIEQLNKFSSPSLTQ
                     DNKRKVQEECTKYLIGTKHFIVGDTDPHPTPEAIDELYTAMHRADVFYELLLHFVDLE
                     FEARRECMLIFSICLGYSKDNKFVTVDYLVSQPKTISLMLRTAEVALQQKGCQDIFLT
                     VGNMIIECIKYEQLCRIILKDPQLWKFFEFAKLGNFEISTESLQILSAAFTAHPKLVS
                     KEFFSNEINIIRFIKCINKLMAHGSYVTKRQSTKLLASLIVIRSNNALMNIYINSPEN
                     LKLIMTLMTDKSKNLQLEAFNVFKVMVANPRKSKPVFDILVKNRDKLLTYFKTFGLDS
                     QDSTFLDEREFIVQEIDSLPRIISSTTEVSNNNASSSNVASITSPSSVMNNQSSILTH
                     STSPDSR"
     gene            complement(86225..88786)
                     /gene="PXA2"
                     /locus_tag="YKL188C"
                     /gene_synonym="PAT1"
     mRNA            complement(86225..88786)
                     /gene="PXA2"
                     /locus_tag="YKL188C"
                     /gene_synonym="PAT1"
                     /product="ATP-binding cassette long-chain fatty acid
                     transporter PXA2"
     CDS             complement(86225..88786)
                     /gene="PXA2"
                     /locus_tag="YKL188C"
                     /gene_synonym="PAT1"
                     /experiment="EXISTENCE:direct assay:GO:0005777 peroxisome
                     [PMID:27663510]"
                     /experiment="EXISTENCE:direct assay:GO:0005779 integral
                     component of peroxisomal membrane [PMID:9395310]"
                     /experiment="EXISTENCE:direct assay:GO:0042626
                     ATPase-coupled transmembrane transporter activity
                     [PMID:9395310]"
                     /experiment="EXISTENCE:direct assay:GO:1902001 fatty acid
                     transmembrane transport [PMID:9395310]"
                     /note="Subunit of heterodimeric peroxisomal ABC transport
                     complex, with Pxa1p; required for import of long-chain
                     fatty acids into peroxisomes; similar to human
                     adrenoleukodystrophy transportesr ABCD1 and ABCD2, and
                     ALD-related proteins; mutations in ABCD1 cause X-linked
                     adrenoleukodystrophy (X-ALD), a peroxisomal disorder;
                     human ABCD1 and ABCD2 can each partially complement yeast
                     pxa1 pxa2 double null mutant"
                     /codon_start=1
                     /product="ATP-binding cassette long-chain fatty acid
                     transporter PXA2"
                     /protein_id="DAA08978.1"
                     /db_xref="SGD:S000001671"
                     /translation="MISTASAFYQKHRVNLLRSSYIILLLATLYNSNSSSSNNKTDKK
                     DSESTVLENKKIEEGKETAVDREEDESSKEELTIVSKHSTDSEDGAIIIDKESKTNHK
                     GGERKGKVDFLFKLLLHDKKCLILFITQAILLNIRTLLSLRVATLDGQLVSTLVRAQY
                     ANFTKILLGKWMILGIPASFINSLISYTTKLCAVTINRKVSDFLLSKYLSNHHTFYSV
                     ASAESVSEIQDNLTKDIYTFSMNSSLLLNQLLKPMLDLILCSFKLLTSNTSVMGEGTL
                     ALGLIVYASNSLLKLIQPNFTRLTMASASLESWFRSLHSNLHSSNEEIALLRGQKREL
                     ENVDYSFYRLVLFLNREIKARAIYDVATAFVIKYTWGAAGLVLCSIPIFFKNKPSEDT
                     LQLKEPGNDMTADFITNRRLLVTASSSIGRFVELKRNIQQLRGIRLRLNKFNDLLDAN
                     KGDDEKEPRDERCIVEYDDSRIKFENIPLITPANQVLVPELSFDLKHGNHLLIIGPNG
                     CGKSSLFRILGGLWPIRATPNKNHQSKLIMPRRTVDRDCAIFYLPQRPYMGNRSTFRE
                     QIIYPDSIEQFKERYHNDYDLGDADLIKILQLLDLEDLVTENMSLLLAQRTSKNDSQQ
                     LSTEDNQSPCAIKVRDAFSIVRNWSEELTIGVQQRLAMARMYYHKPKFAVLDECTSAV
                     APEMEQRMYENAQNFGISLISVCHRTSLWHFHNYLLKFDGKGGYQFGPFNPKERLCNE
                     EKLLELNAILDQQVPLWERKLKDLTIAKESNIIRKSETNLNLFEKIEDPKTSKSNALF
                     NANKGQRITSPTGQETSKRLPLFSQPSSSASSNLLRNNKSLNKKVKTKKEEGKER"
     rep_origin      88789..89287
                     /note="ARS1104; Putative replication origin; identified in
                     multiple array studies, not yet confirmed by plasmid-based
                     assay"
                     /db_xref="SGD:S000130138"
     gene            complement(89284..91536)
                     /gene="FAT3"
                     /locus_tag="YKL187C"
     mRNA            complement(89284..91536)
                     /gene="FAT3"
                     /locus_tag="YKL187C"
                     /product="Fat3p"
     CDS             complement(89284..91536)
                     /gene="FAT3"
                     /locus_tag="YKL187C"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0071944 cell
                     periphery [PMID:26928762]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015909
                     long-chain fatty acid transport [PMID:23349476]"
                     /note="Protein required for fatty acid uptake; protein
                     abundance increases in cortical patches in response to
                     oleate exposure; the authentic, non-tagged protein is
                     detected in a phosphorylated state in highly purified
                     mitochondria in high-throughput studies; FAT3 has a
                     paralog, YLR413W, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Fat3p"
                     /protein_id="DAA08979.1"
                     /db_xref="SGD:S000001670"
                     /translation="MRIEKHRTPLSKGIIWTILSVCLLFMFTTLILVIVATAGSTANY
                     KPLTNIYIGEADIKHINVSKVIPQIGPILTILGSALTAPNSSLDDIFGAMKNIADTPA
                     LTPLLTLLSNADNTTVTIESLTELAPLAISGNPASSTRQLTEINGLLKYSDNATETLD
                     GLSRLVSASLSSASSNSSSDSTTLVLDLLKDSDNPQNSTDALLTLNNLTMSEKAQLLP
                     VFRLFAFSTNQTATMTALATLMNTTISSSLAQTLLTQLQNTISNGGSLNNTFSTLQPL
                     VPQASAPAFDAVELLLNQTTSTNQTLSTLSDLLEQNLTQSSSAKKAFAALTQLMENSD
                     NSTMVVTSVQSLAAVTNTTQSTQQLIGLDDVISSSSNTNETLSILSELQSGLSGNSSS
                     VQYIPYLFSLLGASTDPKTTFSSLVTLTSWAQENPQTFLPILDILADAKSVQPISAEE
                     LNAMTPNILEYLKIPIYYRLSIFTLCHANLENKILDCNSPHAVQNLDFRSIIYDALVT
                     SDFQPYLNALNISANDLYLEGKLLHREHQYVPAVRSVLALNLLAIIFSFFTMIFIILL
                     YFNRYMFKQPLWLIALALHVCVGVATVLAAIIISVMIAIIKSGTADDKYGVVFKAGPA
                     YTGLIWTAFALSFIATGLIIYTWWRNRRSGRYMSGSVTNRKGEIYTYGDGSAISADRF
                     GDHNLGDDDDADFEKQVNRNEITAIDNSSSANNTDVTGSTSNRTELSHPDVTPKDSNG
                     PVNNNAHLVA"
     gene            complement(92744..93298)
                     /gene="MTR2"
                     /locus_tag="YKL186C"
     mRNA            complement(92744..93298)
                     /gene="MTR2"
                     /locus_tag="YKL186C"
                     /product="Mtr2p"
     CDS             complement(92744..93298)
                     /gene="MTR2"
                     /locus_tag="YKL186C"
                     /experiment="EXISTENCE:genetic interaction:GO:0000055
                     ribosomal large subunit export from nucleus
                     [PMID:17434126]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000055
                     ribosomal large subunit export from nucleus
                     [PMID:17434126|PMID:31439809]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000056
                     ribosomal small subunit export from nucleus
                     [PMID:22956913]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016973
                     poly(A)+ mRNA export from nucleus
                     [PMID:7865887|PMID:9774696]"
                     /experiment="EXISTENCE:physical interaction:GO:0005515
                     protein binding [PMID:10952996]"
                     /experiment="EXISTENCE:physical interaction:GO:0042272
                     nuclear RNA export factor complex [PMID:9774696]"
                     /note="mRNA transport regulator; essential nuclear
                     protein; Mex67p and Mtr2p form a mRNA export complex which
                     binds to RNA"
                     /codon_start=1
                     /product="Mtr2p"
                     /protein_id="DAA08980.1"
                     /db_xref="SGD:S000001669"
                     /translation="MNTNSNTMVMNDANQAQITATFTKKILAHLDDPDSNKLAQFVQL
                     FNPNNCRIIFNATPFAQATVFLQMWQNQVVQTQHALTGVDYHAIPGSGTLICNVNCKV
                     RFDESGRDKMGQDATVPIQPNNTGNRNRPNDMNKPRPLWGPYFGISLQLIIDDRIFRN
                     DFNGVISGFNYNMVYKPEDSLLKI"
     gene            94499..96265
                     /gene="ASH1"
                     /locus_tag="YKL185W"
     mRNA            94499..96265
                     /gene="ASH1"
                     /locus_tag="YKL185W"
                     /product="DNA-binding transcription repressor ASH1"
     CDS             94499..96265
                     /gene="ASH1"
                     /locus_tag="YKL185W"
                     /experiment="EXISTENCE:direct assay:GO:0000987
                     cis-regulatory region sequence-specific DNA binding
                     [PMID:11171979]"
                     /experiment="EXISTENCE:direct assay:GO:0001227 DNA-binding
                     transcription repressor activity, RNA polymerase
                     II-specific [PMID:19841732]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:8625408|PMID:8625409|PMID:9566907]"
                     /experiment="EXISTENCE:direct assay:GO:0005933 cellular
                     bud [PMID:8625408|PMID:8625409]"
                     /experiment="EXISTENCE:direct assay:GO:0033698 Rpd3L
                     complex [PMID:16286007|PMID:16314178|PMID:19040720]"
                     /experiment="EXISTENCE:direct assay:GO:0070210
                     Rpd3L-Expanded complex [PMID:19040720]"
                     /experiment="EXISTENCE:direct assay:GO:1900477 negative
                     regulation of G1/S transition of mitotic cell cycle by
                     negative regulation of transcription from RNA polymerase
                     II promoter [PMID:19841732]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000122
                     negative regulation of transcription by RNA polymerase II
                     [PMID:8625408|PMID:8625409]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0001227
                     DNA-binding transcription repressor activity, RNA
                     polymerase II-specific [PMID:11171979]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1900461
                     positive regulation of pseudohyphal growth by positive
                     regulation of transcription from RNA polymerase II
                     promoter [PMID:11046133]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1900477
                     negative regulation of G1/S transition of mitotic cell
                     cycle by negative regulation of transcription from RNA
                     polymerase II promoter [PMID:19841732]"
                     /note="Component of the Rpd3L histone deacetylase complex;
                     zinc-finger inhibitor of HO transcription; mRNA is
                     localized and translated in the distal tip of anaphase
                     cells, resulting in accumulation of Ash1p in daughter cell
                     nuclei and inhibition of HO expression; potential Cdc28p
                     substrate"
                     /codon_start=1
                     /product="DNA-binding transcription repressor ASH1"
                     /protein_id="DAA08981.1"
                     /db_xref="SGD:S000001668"
                     /translation="MSSLYIKTPLHALSAGPDSHANSSYYDNLLLPSFSNLSSNISRN
                     NITTDNNINSASPRKYSFHSLNVSPILSPISLANEILGKKSNTAPASPHHMDYNPISS
                     LTPGNSPEFNKASLSQISFTNPLNYGSGLGFSSNSQPRLPLLDRLSSVSLSKRPERPQ
                     QSLPSLRHLQLLPSPLLQENAARFPDTSKRTSNWKTDLTHWCKDTNYQDYVKIREEVA
                     HFKPLSIPNLTNNQNNDSFNYGKELESTRSSKFHSPSKESFDRTKLIPSILEAKDQFK
                     DLSNNAWSITPPVTPPMSPPTNRTMERTTLRGVEASFFEGKSSNNDSIFNPIISEKLV
                     QEVKHQRQLRGNSFPMPNASHKKTNSFKALQIKKLLANRDILSNNSKSNVRKPSKNKI
                     SKQASNVFGNTARQLVMKLDNASYSSVSASSSPSPSTPTKSGKMRSRSSSPVRPKAYT
                     PSPRSPNYHRFALDSPPQSPRRSSNSSITKKGSRRSSGSSPTRHTTRVCVSCHSSDSP
                     CWRPSWSPRKQDQLCNSCGLRYKKTHTRCLNDLCRKIPTKGEINIMKSNGIDKEFVPE
                     RNCEIEGYRCLFCNYITETVEN"
     gene            96757..98157
                     /gene="SPE1"
                     /locus_tag="YKL184W"
                     /gene_synonym="ORD1"
                     /gene_synonym="SPE10"
     mRNA            96757..98157
                     /gene="SPE1"
                     /locus_tag="YKL184W"
                     /gene_synonym="ORD1"
                     /gene_synonym="SPE10"
                     /product="ornithine decarboxylase SPE1"
     CDS             96757..98157
                     /gene="SPE1"
                     /locus_tag="YKL184W"
                     /gene_synonym="ORD1"
                     /gene_synonym="SPE10"
                     /EC_number="4.1.1.17"
                     /experiment="EXISTENCE:direct assay:GO:0004586 ornithine
                     decarboxylase activity [PMID:2681188]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0009446
                     putrescine biosynthetic process [PMID:7929015]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015940
                     pantothenate biosynthetic process [PMID:11154694]"
                     /note="Ornithine decarboxylase; catalyzes the first step
                     in polyamine biosynthesis; degraded in a
                     proteasome-dependent manner in the presence of excess
                     polyamines; deletion decreases lifespan, and increases
                     necrotic cell death and ROS generation"
                     /codon_start=1
                     /product="ornithine decarboxylase SPE1"
                     /protein_id="DAA08982.1"
                     /db_xref="SGD:S000001667"
                     /translation="MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLE
                     LKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDPGEENSFFICDLGEVKRLFNNW
                     VKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANP
                     CKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYG
                     CEMENVDVLLKAIKELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLP
                     PLKILDVGGGFQFESFKESTAVLRLALEEFFPVGCGVDIIAEPGRYFVATAFTLASHV
                     IAKRKLSENEAMIYTNDGVYGNMNCILFDHQEPHPRTLYHNLEFHYDDFESTTAVLDS
                     INKTRSEYPYKVSIWGPTCDGLDCIAKEYYMKHDVIVGDWFYFPALGAYTSSAATQFN
                     GFEQTADIVYIDSELD"
     rep_origin      98364..98523
                     /note="ARS1125; Autonomously Replicating Sequence"
                     /db_xref="SGD:S000119035"
     gene            complement(98395..98607)
                     /locus_tag="YKL183C-A"
     mRNA            complement(98395..98607)
                     /locus_tag="YKL183C-A"
                     /product="hypothetical protein"
     CDS             complement(98395..98607)
                     /locus_tag="YKL183C-A"
                     /note="hypothetical protein; identified by fungal homology
                     and RT-PCR"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA08983.1"
                     /db_xref="SGD:S000028558"
                     /translation="MYSKILLYRSNVLFMNFFSVFVCTIGTLFLVFADVYVLASAFFQ
                     SKKEKETKFKHLHYQKRSCFFLANIH"
     gene            98721..99641
                     /gene="LOT5"
                     /locus_tag="YKL183W"
     mRNA            98721..99641
                     /gene="LOT5"
                     /locus_tag="YKL183W"
                     /product="Lot5p"
     CDS             98721..99641
                     /gene="LOT5"
                     /locus_tag="YKL183W"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /note="hypothetical protein; gene expression increases in
                     cultures shifted to a lower temperature; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Lot5p"
                     /protein_id="DAA08984.1"
                     /db_xref="SGD:S000001666"
                     /translation="MMKKKPKCQIARTKPSVENVIPYNQFKKTQPRFNGNFSALNNEE
                     YIILFGGGRDLILGSLTPCSSSHLSNQANPQDTSEYGTDLFILNSCIIIWFNGLGYGL
                     EIPYSSVLYHASRRLPDGREGLQLEILLTLERDEVLDMLYQSLAPQACEFDGEEAHAF
                     TVRSVELTIRPKYSIYDRHYNNEIETLFTFENFGVNRGDDLVNNCNEALAVCMDLHGE
                     DVQDQDQEQYQDPSMAFEGAQDLNATYSGLGDTLHGPPVYQNDGLADDLDGDLVMDNV
                     VSRGGPEASMSMEFYANQNLAGRKNSRDNE"
     gene            100671..106826
                     /gene="FAS1"
                     /locus_tag="YKL182W"
     mRNA            100671..106826
                     /gene="FAS1"
                     /locus_tag="YKL182W"
                     /product="tetrafunctional fatty acid synthase subunit
                     FAS1"
     CDS             100671..106826
                     /gene="FAS1"
                     /locus_tag="YKL182W"
                     /EC_number="1.3.1.9"
                     /EC_number="2.3.1.38"
                     /EC_number="2.3.1.39"
                     /EC_number="2.3.1.86"
                     /EC_number="3.1.2.14"
                     /EC_number="4.2.1.59"
                     /experiment="EXISTENCE:direct assay:GO:0004313
                     [acyl-carrier-protein] S-acetyltransferase activity
                     [PMID:374077]"
                     /experiment="EXISTENCE:direct assay:GO:0004314
                     [acyl-carrier-protein] S-malonyltransferase activity
                     [PMID:365179|PMID:374077]"
                     /experiment="EXISTENCE:direct assay:GO:0004319
                     enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific)
                     activity [PMID:374077]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0005811 lipid
                     droplet [PMID:17803462]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:6025308]"
                     /experiment="EXISTENCE:direct assay:GO:0005835 fatty acid
                     synthase complex [PMID:65153]"
                     /experiment="EXISTENCE:direct assay:GO:0016409
                     palmitoyltransferase activity [PMID:365179]"
                     /experiment="EXISTENCE:direct assay:GO:0019171
                     3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
                     [PMID:374077]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004312 fatty
                     acid synthase activity [PMID:1100391|PMID:65153]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004313
                     [acyl-carrier-protein] S-acetyltransferase activity
                     [PMID:1100391]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004314
                     [acyl-carrier-protein] S-malonyltransferase activity
                     [PMID:1100391]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004319
                     enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific)
                     activity [PMID:1100391]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016409
                     palmitoyltransferase activity [PMID:1100391]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0019171
                     3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
                     [PMID:1100391]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042759
                     long-chain fatty acid biosynthetic process
                     [PMID:1735446|PMID:4127627]"
                     /note="Beta subunit of fatty acid synthetase; complex
                     catalyzes the synthesis of long-chain saturated fatty
                     acids; contains acetyltransacylase, dehydratase, enoyl
                     reductase, malonyl transacylase, and palmitoyl
                     transacylase activities"
                     /codon_start=1
                     /product="tetrafunctional fatty acid synthase subunit
                     FAS1"
                     /protein_id="DAA08985.1"
                     /db_xref="SGD:S000001665"
                     /translation="MDAYSTRPLTLSHGSLEHVLLVPTASFFIASQLQEQFNKILPEP
                     TEGFAADDEPTTPAELVGKFLGYVSSLVEPSKVGQFDQVLNLCLTEFENCYLEGNDIH
                     ALAAKLLQENDTTLVKTKELIKNYITARIMAKRPFDKKSNSALFRAVGEGNAQLVAIF
                     GGQGNTDDYFEELRDLYQTYHVLVGDLIKFSAETLSELIRTTLDAEKVFTQGLNILEW
                     LENPSNTPDKDYLLSIPISCPLIGVIQLAHYVVTAKLLGFTPGELRSYLKGATGHSQG
                     LVTAVAIAETDSWESFFVSVRKAITVLFFIGVRCYEAYPNTSLPPSILEDSLENNEGV
                     PSPMLSISNLTQEQVQDYVNKTNSHLPAGKQVEISLVNGAKNLVVSGPPQSLYGLNLT
                     LRKAKAPSGLDQSRIPFSERKLKFSNRFLPVASPFHSHLLVPASDLINKDLVKNNVSF
                     NAKDIQIPVYDTFDGSDLRVLSGSISERIVDCIIRLPVKWETTTQFKATHILDFGPGG
                     ASGLGVLTHRNKDGTGVRVIVAGTLDINPDDDYGFKQEIFDVTSNGLKKNPNWLEEYH
                     PKLIKNKSGKIFVETKFSKLIGRPPLLVPGMTPCTVSPDFVAATTNAGYTIELAGGGY
                     FSAAGMTAAIDSVVSQIEKGSTFGINLIYVNPFMLQWGIPLIKELRSKGYPIQFLTIG
                     AGVPSLEVASEYIETLGLKYLGLKPGSIDAISQVINIAKAHPNFPIALQWTGGRGGGH
                     HSFEDAHTPMLQMYSKIRRHPNIMLIFGSGFGSADDTYPYLTGEWSTKFDYPPMPFDG
                     FLFGSRVMIAKEVKTSPDAKKCIAACTGVPDDKWEQTYKKPTGGIVTVRSEMGEPIHK
                     IATRGVMLWKEFDETIFNLPKNKLVPTLEAKRDYIISRLNADFQKPWFATVNGQARDL
                     ATMTYEEVAKRLVELMFIRSTNSWFDVTWRTFTGDFLRRVEERFTKSKTLSLIQSYSL
                     LDKPDEAIEKVFNAYPAAREQFLNAQDIDHFLSMCQNPMQKPVPFVPVLDRRFEIFFK
                     KDSLWQSEHLEAVVDQDVQRTCILHGPVAAQFTKVIDEPIKSIMDGIHDGHIKKLLHQ
                     YYGDDESKIPAVEYFGGESPVDVQSQVDSSSVSEDSAVFKATSSTDEESWFKALAGSE
                     INWRHASFLCSFITQDKMFVSNPIRKVFKPSQGMVVEISNGNTSSKTVVTLSEPVQGE
                     LKPTVILKLLKENIIQMEMIENRTMDGKPVSLPLLYNFNPDNGFAPISEVMEDRNQRI
                     KEMYWKLWIDEPFNLDFDPRDVIKGKDFEITAKEVYDFTHAVGNNCEDFVSRPDRTML
                     APMDFAIVVGWRAIIKAIFPNTVDGDLLKLVHLSNGYKMIPGAKPLQVGDVVSTTAVI
                     ESVVNQPTGKIVDVVGTLSRNGKPVMEVTSSFFYRGNYTDFENTFQKTVEPVYQMHIK
                     TSKDIAVLRSKEWFQLDDEDFDLLNKTLTFETETEVTFKNANIFSSVKCFGPIKVELP
                     TKETVEIGIVDYEAGASHGNPVVDFLKRNGSTLEQKVNLENPIPIAVLDSYTPSTNEP
                     YARVSGDLNPIHVSRHFASYANLPGTITHGMFSSASVRALIENWAADSVSSRVRGYTC
                     QFVDMVLPNTALKTSIQHVGMINGRKLIKFETRNEDDVVVLTGEAEIEQPVTTFVFTG
                     QGSQEQGMGMDLYKTSKAAQDVWNRADNHFKDTYGFSILDIVINNPVNLTIHFGGEKG
                     KRIRENYSAMIFETIVDGKLKTEKIFKEINEHSTSYTFRSEKGLLSATQFTQPALTLM
                     EKAAFEDLKSKGLIPADATFAGHSLGEYAALASLADVMSIESLVEVVFYRGMTMQVAV
                     PRDELGRSNYGMIAINPGRVAASFSQEALQYVVERVGKRTGWLVEIVNYNVENQQYVA
                     AGDLRALDTVTNVLNFIKLQKIDIIELQKSLSLEEVEGHLFEIIDEASKKSAVKPRPL
                     KLERGFACIPLVGISVPFHSTYLMNGVKPFKSFLKKNIIKENVKVARLAGKYIPNLTA
                     KPFQVTKEYFQDVYDLTGSEPIKEIIDNWEKYEQS"
     gene            107316..108599
                     /gene="PRS1"
                     /locus_tag="YKL181W"
                     /gene_synonym="PRP1"
     mRNA            107316..108599
                     /gene="PRS1"
                     /locus_tag="YKL181W"
                     /gene_synonym="PRP1"
                     /product="ribose phosphate diphosphokinase subunit PRS1"
     CDS             107316..108599
                     /gene="PRS1"
                     /locus_tag="YKL181W"
                     /gene_synonym="PRP1"
                     /EC_number="2.7.6.1"
                     /experiment="EXISTENCE:direct assay:GO:0002189 ribose
                     phosphate diphosphokinase complex [PMID:15280369]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:11101685|PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
                     stress granule [PMID:26777405]"
                     /experiment="EXISTENCE:genetic interaction:GO:0004749
                     ribose phosphate diphosphokinase activity [PMID:15280369]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006015
                     5-phosphoribose 1-diphosphate biosynthetic process
                     [PMID:15280369]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006015
                     5-phosphoribose 1-diphosphate biosynthetic process
                     [PMID:10212224]"
                     /experiment="EXISTENCE:physical interaction:GO:0031505
                     fungal-type cell wall organization [PMID:15470112]"
                     /note="5-phospho-ribosyl-1(alpha)-pyrophosphate
                     synthetase; synthesizes PRPP, which is required for
                     nucleotide, histidine, and tryptophan biosynthesis; plays
                     a key role in cell wall integrity (CWI) pathway; one of
                     five related enzymes, which are active as heteromultimeric
                     complexes; missense mutations in human homolog PRPS1 are
                     associated with neuropathic Arts syndrome and
                     Charcot-Marie Tooth (CMTX5) disease"
                     /codon_start=1
                     /product="ribose phosphate diphosphokinase subunit PRS1"
                     /protein_id="DAA08986.1"
                     /db_xref="SGD:S000001664"
                     /translation="MRKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQI
                     GVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARKITAVIPQFPYSKQCKMKR
                     HRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVE
                     DYEDAVVVSKNPGGTKRVTALADSLKINFAMIHTDRRRSKDLYSQNKDLQQLKLRKQS
                     MLRKNRPIIRQGDHPNEEENIILSNGIQTARIRNGHVIGDDEADDDEDAILESDSELH
                     SIDGLDSHGLGGTYDAVDSEDEEEIPVLYREQLITLVGNVRGRSAIILDDMIDRPGSF
                     ISAAEHLVQNCGAKKVYVVATHGIFTGDCLEELEKSDAIDTIVVTNTYPISGERIAGS
                     KKLVTIDVSPIFAECIRRDHYGESISVLFDSLAAL"
     gene            109269..110129
                     /gene="RPL17A"
                     /locus_tag="YKL180W"
                     /gene_synonym="RPL17"
     mRNA            join(109269..109577,109884..110129)
                     /gene="RPL17A"
                     /locus_tag="YKL180W"
                     /gene_synonym="RPL17"
                     /product="ribosomal 60S subunit protein L17A"
     CDS             join(109269..109577,109884..110129)
                     /gene="RPL17A"
                     /locus_tag="YKL180W"
                     /gene_synonym="RPL17"
                     /experiment="EXISTENCE:direct assay:GO:0002181 cytoplasmic
                     translation [PMID:18782943]"
                     /experiment="EXISTENCE:direct assay:GO:0003735 structural
                     constituent of ribosome [PMID:18782943]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:11914276]"
                     /experiment="EXISTENCE:direct assay:GO:0022625 cytosolic
                     large ribosomal subunit [PMID:18782943]"
                     /experiment="EXISTENCE:direct assay:GO:0030687
                     preribosome, large subunit precursor [PMID:23268442]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000448
                     cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of
                     tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA,
                     LSU-rRNA) [PMID:23268442]"
                     /note="Ribosomal 60S subunit protein L17A; required for
                     processing of 27SB pre-rRNA and formation of stable 66S
                     assembly intermediates; copurifies with the Dam1 complex
                     (aka DASH complex); homologous to mammalian ribosomal
                     protein L17 and bacterial L22; RPL17A has a paralog,
                     RPL17B, that arose from the whole genome duplication;
                     protein abundance increases in response to DNA replication
                     stress"
                     /codon_start=1
                     /product="ribosomal 60S subunit protein L17A"
                     /protein_id="DAA08987.1"
                     /db_xref="SGD:S000001663"
                     /translation="MARYGATSTNPAKSASARGSYLRVSFKNTRETAQAINGWELTKA
                     QKYLEQVLDHQRAIPFRRFNSSIGRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAANA
                     EAKGLDATKLYVSHIQVNQAPKQRRRTYRAHGRINKYESSPSHIELVVTEKEEAVAKA
                     AEKKVVRLTSRQRGRIAAQKRIAA"
     gene            complement(110464..112503)
                     /gene="COY1"
                     /locus_tag="YKL179C"
     mRNA            complement(110464..112503)
                     /gene="COY1"
                     /locus_tag="YKL179C"
                     /product="Coy1p"
     CDS             complement(110464..112503)
                     /gene="COY1"
                     /locus_tag="YKL179C"
                     /experiment="EXISTENCE:direct assay:GO:0000139 Golgi
                     membrane [PMID:31073031]"
                     /experiment="EXISTENCE:direct assay:GO:0000149 SNARE
                     binding [PMID:31073031]"
                     /experiment="EXISTENCE:direct assay:GO:0048211 Golgi
                     vesicle docking [PMID:31073031]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000139
                     Golgi membrane [PMID:12429822]"
                     /experiment="EXISTENCE:genetic interaction:GO:0048193
                     Golgi vesicle transport [PMID:12429822]"
                     /note="Golgi membrane protein with similarity to mammalian
                     CASP; packaged into COPII vesicles for trafficking between
                     ER and Golgi; genetic interactions with GOS1 (encoding a
                     Golgi snare protein) suggest a role in Golgi function"
                     /codon_start=1
                     /product="Coy1p"
                     /protein_id="DAA08988.1"
                     /db_xref="SGD:S000001662"
                     /translation="MDTSVYSHALDIWAKADLTNLQRELDADVIEIKDKETLSLNSRK
                     SLATETKKFKKLEPEEKLNNVNKIIKQYQREIDNLTQRSKFSEKVLFDVYEKLSEAPD
                     PQPLLQSSLEKLGKIDDSKELKEKISYLEDKLAKYADYETLKSRLLDLEQSSAKTLAK
                     RLTAKTQEINSTWEEKGRNWKEREADLLKQLTNVQEQNKALEAKISKNIDIEGNGNED
                     GDQENNQKEVSTRIAEYNLVTQELETTQARIYQLEKRNEELSGALAKATSEAEKETEL
                     HAKELKLNQLESENALLSASYEQERKSTSHAINELKEQLNSVVAESESYKSELETVRR
                     KLNNYSDYNKIKEELSALKKIEFGVNEDDSDNDIRSEDKNDNTFESSLLSANKKLQAT
                     LAEYRSKSTAQEEERNELKKSVDQLKQQIATLKEANEKLETDLEKVENVSPHFNETAS
                     MMSGVTRQMNNRTSHKMSPTSSIIGIPEDGELSGNQSTILPIVTKQRDRFRSRNMDLE
                     KQLRQGNSEKGKLKLEISKLKGDNTKLYERIRYLQSYNNNNAPVNQSTERIDVESQYS
                     RVYDESLHPMANFRQNELNHYKNKKLSALEKLFSSFAKVILQNKMTRMVFLFYCIGLH
                     GLVFMMSMYVINISGYMTPEVGIVQSAKSSSNLNGGLGGAEKVAAGVGSVHGINR"
     gene            complement(113215..114627)
                     /gene="STE3"
                     /locus_tag="YKL178C"
                     /gene_synonym="DAF2"
     mRNA            complement(113215..114627)
                     /gene="STE3"
                     /locus_tag="YKL178C"
                     /gene_synonym="DAF2"
                     /product="Ste3p"
     CDS             complement(113215..114627)
                     /gene="STE3"
                     /locus_tag="YKL178C"
                     /gene_synonym="DAF2"
                     /experiment="EXISTENCE:direct assay:GO:0000755 cytogamy
                     [PMID:17369365]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005887 integral
                     component of plasma membrane [PMID:3006051]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000750
                     pheromone-dependent signal transduction involved in
                     conjugation with cellular fusion [PMID:3006051]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000755
                     cytogamy [PMID:17369365]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004933
                     mating-type a-factor pheromone receptor activity
                     [PMID:3006051]"
                     /note="Receptor for a factor pheromone; couples to MAP
                     kinase cascade to mediate pheromone response; transcribed
                     in alpha cells and required for mating by alpha cells,
                     ligand bound receptors endocytosed and recycled to the
                     plasma membrane; GPCR"
                     /codon_start=1
                     /product="Ste3p"
                     /protein_id="DAA08989.1"
                     /db_xref="SGD:S000001661"
                     /translation="MSYKSAIIGLCLLAVILLAPPLAWHSHTKNIPAIILITWLLTMN
                     LTCIVDAAIWSDDDFLTRWDGKGWCDIVIKLQVGANIGISCAVTNIIYNLHTILKADS
                     VLPDLSSWTKIVKDLVISLFTPVMVMGFSYLLQVFRYGIARYNGCQNLLSPTWITTVL
                     YTMWMLIWSFVGAVYATLVLFVFYKKRKDVRDILHCTNSGLNLTRFARLLIFCFIIIL
                     VMFPFSVYTFVQDLQQVEGHYTFKNTHSSTIWNTIIKFDPGRPIYNIWLYVLMSYLVF
                     LIFGLGSDALHMYSKFLRSIKLGFVLDMWKRFIDKNKEKRVGILLNKLSSRKESRNPF
                     STDSENYISTCTENYSPCVGTPISQAHFYVDYRIPDDPRKSQNKSKKYLFADKETDDI
                     LDEIDLKESRHIPYVTQGQSFDDEISLGGFSKVTLDYSEKLHNSASSNFEGESLCYSP
                     ASKEENSSSNEHSSENTAGP"
     gene            complement(115500..117986)
                     /gene="LST4"
                     /locus_tag="YKL176C"
     mRNA            complement(115500..117986)
                     /gene="LST4"
                     /locus_tag="YKL176C"
                     /product="Lst4p"
     CDS             complement(115500..117986)
                     /gene="LST4"
                     /locus_tag="YKL176C"
                     /experiment="EXISTENCE:direct assay:GO:0005096 GTPase
                     activator activity [PMID:26387955]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:26387955]"
                     /experiment="EXISTENCE:direct assay:GO:0005774 vacuolar
                     membrane [PMID:26387955]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0043547 positive
                     regulation of GTPase activity [PMID:26387955]"
                     /experiment="EXISTENCE:direct assay:GO:1990877 Lst4-Lst7
                     complex [PMID:26387955]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1904263
                     positive regulation of TORC1 signaling [PMID:26387955]"
                     /note="Subunit of the Lst4p-Lst7p GTPase activating
                     protein complex for Gtr2p; stimulates the GTPase activity
                     of Rag family GTPase Gtr2p, within the context of the
                     Gtr1p-Gtr2p heterodimer, after amino acid stimulation;
                     required for activation of TORC1 in response to amino acid
                     stimulation; recruited to the vacuolar membrane during
                     amino acid starvation and released from the membrane by
                     TORC1; required for the transport of amino acid permease
                     Gap1p from the Golgi to the cell surface"
                     /codon_start=1
                     /product="Lst4p"
                     /protein_id="DAA08990.1"
                     /db_xref="SGD:S000001659"
                     /translation="MLGNLLRNKTSSSGFEKSSEHSDFSSVVPNVPVYCKAASTGTTK
                     TAAGALLDTAVNVEKPSEMLSTTSPPILDHISDDLKLKLFGSRDIPYSRPIDTLQNNG
                     GLGTDKITSINEKTYAFRILIIEEAGQMACRNNYRDIFDYTTSKISNSMEQIRPSELK
                     EYIFGSPVRSSDLTQCDKIRTIPNSDLVLITRIFYYTHQYNRIAISLCIPRILLPVVA
                     ESWSSISSWLTQTQKMLIGFLTKNRIMQENTGNYSNNSVIKLSNIDIRTHYPKEIEIM
                     VQTLQKRVIPGLRSMSEIPRLFLYPETFKEFVHVWFKSIFNWIEIKDGPKLGFLPLLM
                     AMIISDYRHTIRELKTSKIVILSGNMVVANKLLFILSALLEPKYKGQITIRRENIRSD
                     SSAVSRNKSNNNFVDKPETELSTLTSTDNLLSRTENNSNHNYNNSNVSSNSIGSPNFH
                     SLRKGWQIPNRRNSNTSVSVSSSESLAEVIQPSSFKSGSSSLHYLSSSISSQPGSYGS
                     WFNKRPTISQFFQPSPSLKHNESWERLQTTAGNMQRTSSSSSLQQATSRLSLTTPQQS
                     PSISEYDEYPWMGTPGSPNVGDVSHAPPLVKNISYKFPLKNVELKRDCQRISQDDLLD
                     EAFERICQPSLADLNSTYEIFPGNSSYADILTTDSDIDDGLMNKPLELLPKYTMYLTH
                     FNNFFQLQACPAGQESESRITNSMKIDLLKADYTRSLLVSLRSRDIRDVALKREFTGN
                     NNNNSNQNIYDENFVGKRKYVLKQKTRKIFSCGKIGKLSTSLENCVNFVENSIKSAMM
                     LYDDNGIDSELRDSEALRIFSSLVHYCNAG"
     gene            118793..120304
                     /gene="ZRT3"
                     /locus_tag="YKL175W"
     mRNA            118793..120304
                     /gene="ZRT3"
                     /locus_tag="YKL175W"
                     /product="Zn(2+) transporter ZRT3"
     CDS             118793..120304
                     /gene="ZRT3"
                     /locus_tag="YKL175W"
                     /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
                     vacuole membrane [PMID:10856230]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005385 zinc
                     ion transmembrane transporter activity [PMID:10856230]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006829 zinc
                     ion transport [PMID:10856230]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006882
                     cellular zinc ion homeostasis [PMID:10856230]"
                     /note="Vacuolar membrane zinc transporter; transports zinc
                     from storage in the vacuole to the cytoplasm when needed;
                     transcription is induced under conditions of zinc
                     deficiency"
                     /codon_start=1
                     /product="Zn(2+) transporter ZRT3"
                     /protein_id="DAA08991.1"
                     /db_xref="SGD:S000001658"
                     /translation="MEKIPRWLLFSLISSVLCILGALCVPLLSVAFDSKRNSQSKLVN
                     YGLSLSAGSMITTSLYMLLPRIEKSNRFKVFPGLLLGICLSFFLNYLVHAFASESLVH
                     CADSGDHATGSHIHSKSHSHSHSHSHADSHSNFSNDHDLENAPSEHGYATSSSSVSEN
                     DPLITKDSDRPQMKKKMSLIDLLTRRKSEGECCDLNKCTPLLQSEQPEYIACVPPVIK
                     SSQSERNVPHGCEGSEDNGQSDDKDHRGLVCVENNIGYDLENLSLYRKNFLSSRHHHS
                     SESPENYGSNQLSHSFSSPLGNDVTENPAALADTQYHPENGSLYPHHHHLETPFSKLL
                     SIGMQTCLVLALHKFPEGFIIFYTNRSDSSKSLGFSIFLSLTIHNFVEGFAMTLPFYT
                     VFESKWVAILITAVLGGGSQPLGALIGYFIFKGSTPRDHEPNMDFLLSVTAGFLLVIG
                     LQMFQTGIGFSDGHHHHQGEGDEEMKQSHSSGTTCLKWCCTGVLLILASALFT"
     gene            complement(120380..122236)
                     /gene="TPO5"
                     /locus_tag="YKL174C"
     mRNA            complement(120380..122236)
                     /gene="TPO5"
                     /locus_tag="YKL174C"
                     /product="Tpo5p"
     CDS             complement(120380..122236)
                     /gene="TPO5"
                     /locus_tag="YKL174C"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005794 Golgi
                     apparatus [PMID:15668236]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015203
                     polyamine transmembrane transporter activity
                     [PMID:15668236]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015846
                     polyamine transport [PMID:15668236]"
                     /note="Protein involved in excretion of putrescine and
                     spermidine; putative polyamine transporter in the Golgi or
                     post-Golgi vesicles"
                     /codon_start=1
                     /product="Tpo5p"
                     /protein_id="DAA08992.1"
                     /db_xref="SGD:S000001657"
                     /translation="MPEYTLLADNIRENIVHFDPNGLFDNLHTIVHEDDSQENEEAEH
                     FNYDQVLDKSLLSRGSIVGLGLGLMSPVLGMCTSMAIGLINGGPLTIMLGFLISGVCI
                     WFSSLSLGEIVSKFPMELHVGSAMLAPEKLKLVCSWYTGWLMLIGNWTMSTSITFAGA
                     QLTISLILMTNSNLISEAHLIFYTVIVFYLVVTVVGLVNLKFARFIETINKVCVYWII
                     YAIIFIDILLLVFHKGKFRSLKYALFHFDNNLSGYKSAFLSFIIGFQQSNFTLQGFSM
                     LPALADEVKVPEKDIPRGMSNAVLLSAFSGVIFLIPIMLILPDNDLLFTNHKVLPIVN
                     IFTKSTDSVVLSFFLVLLILGNLLFSGIGSITTSSRAVYSFSRDQAIPYYDKWTYVEP
                     DSQSKVPKNSVVLSMIISYFLGLLALISTAAFNAFIGAAVLCLCSATFIPLVLVLFTR
                     RRAIRSAPVKIRYKFGWFINIVSIVWLLLSMVSVCLPTQVPVTFKTMNYALMVYVFCI
                     LVITGLYFKWGKYNFRLPLADDIKAPIPSDAEETVFELEDSNVEHTLNSGTTVKESVE
                     NNSEEGFIKVHPKSSTENPFEENEENVITDYGDEHHTAEQEFDLADDRRYDI"
     gene            122517..125543
                     /gene="SNU114"
                     /locus_tag="YKL173W"
                     /gene_synonym="GIN10"
     mRNA            122517..125543
                     /gene="SNU114"
                     /locus_tag="YKL173W"
                     /gene_synonym="GIN10"
                     /product="U5 snRNP GTPase SNU114"
     CDS             122517..125543
                     /gene="SNU114"
                     /locus_tag="YKL173W"
                     /gene_synonym="GIN10"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005682 U5 snRNP
                     [PMID:11720284|PMID:11720285]"
                     /experiment="EXISTENCE:direct assay:GO:0030623 U5 snRNA
                     binding [PMID:9848662]"
                     /experiment="EXISTENCE:direct assay:GO:0046540 U4/U6 x U5
                     tri-snRNP complex [PMID:10377396|PMID:10449419]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000349
                     generation of catalytic spliceosome for first
                     transesterification step [PMID:15911574]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000244
                     spliceosomal tri-snRNP complex assembly [PMID:16540695]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000388
                     spliceosome conformational change to release U4 (or
                     U4atac) and U1 (or U11) [PMID:16540695]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000398 mRNA
                     splicing, via spliceosome [PMID:9233818]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0003924 GTPase
                     activity [PMID:9233818]"
                     /note="GTPase component of U5 snRNP involved in mRNA
                     splicing via spliceosome; binds directly to U5 snRNA;
                     proposed to be involved in conformational changes of the
                     spliceosome; similarity to ribosomal translocation factor
                     EF-2"
                     /codon_start=1
                     /product="U5 snRNP GTPase SNU114"
                     /protein_id="DAA08993.1"
                     /db_xref="SGD:S000001656"
                     /translation="MEGDDLFDEFGNLIGVDPFDSDEEESVLDEQEQYQTNTFEGSGN
                     NNEIESRQLTSLGSKKELGISLEHPYGKEVEVLMETKNTQSPQTPLVEPVTERTKLQE
                     HTIFTQLKKNIPKTRYNRDYMLSMANIPERIINVGVIGPLHSGKTSLMDLLVIDSHKR
                     IPDMSKNVELGWKPLRYLDNLKQEIDRGLSIKLNGSTLLCTDLESKSRMINFLDAPGH
                     VNFMDETAVALAASDLVLIVIDVVEGVTFVVEQLIKQSIKNNVAMCFVINKLDRLILD
                     LKLPPMDAYLKLNHIIANINSFTKGNVFSPIDNNIIFASTKLGFTFTIKEFVSYYYAH
                     SIPSSKIDDFTTRLWGSVYYHKGNFRTKPFENVEKYPTFVEFILIPLYKIFSYALSME
                     KDKLKNLLRSNFRVNLSQEALQYDPQPFLKHVLQLIFRQQTGLVDAITRCYQPFELFD
                     NKTAHLSIPGKSTPEGTLWAHVLKTVDYGGAEWSLVRIYSGLLKRGDTVRILDTSQSE
                     SRQKRQLHDISKTETSNEDEDEDDETPSCEVEEIGLLGGRYVYPVHEAHKGQIVLIKG
                     ISSAYIKSATLYSVKSKEDMKQLKFFKPLDYITEAVFKIVLQPLLPRELPKLLDALNK
                     ISKYYPGVIIKVEESGEHVILGNGELYMDCLLYDLRASYAKIEIKISDPLTVFSESCS
                     NESFASIPVSNSISRLGEENLPGLSISVAAEPMDSKMIQDLSRNTLGKGQNCLDIDGI
                     MDNPRKLSKILRTEYGWDSLASRNVWSFYNGNVLINDTLPDEISPELLSKYKEQIIQG
                     FYWAVKEGPLAEEPIYGVQYKLLSISVPSDVNIDVMKSQIIPLMKKACYVGLLTAIPI
                     LLEPIYEVDITVHAPLLPIVEELMKKRRGSRIYKTIKVAGTPLLEVRGQVPVIESAGF
                     ETDLRLSTNGLGMCQLYFWHKIWRKVPGDVLDKDAFIPKLKPAPINSLSRDFVMKTRR
                     RKGISTGGFMSNDGPTLEKYISAELYAQLRENGLVP"
     gene            125759..127042
                     /gene="EBP2"
                     /locus_tag="YKL172W"
     mRNA            125759..127042
                     /gene="EBP2"
                     /locus_tag="YKL172W"
                     /product="Ebp2p"
     CDS             125759..127042
                     /gene="EBP2"
                     /locus_tag="YKL172W"
                     /experiment="EXISTENCE:direct assay:GO:0003729 mRNA
                     binding [PMID:23222640]"
                     /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
                     [PMID:10849420]"
                     /experiment="EXISTENCE:direct assay:GO:0030687
                     preribosome, large subunit precursor
                     [PMID:11583614|PMID:17443350]"
                     /experiment="EXISTENCE:direct assay:GO:0034399 nuclear
                     periphery [PMID:21822217]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000280 nuclear
                     division [PMID:15515129]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006364 rRNA
                     processing [PMID:10849420]"
                     /note="Required for 25S rRNA maturation and 60S ribosomal
                     subunit assembly; localizes to the nucleolus and in foci
                     along nuclear periphery; constituent of 66S pre-ribosomal
                     particles; cooperates with Rrs1p and Mps3p to mediate
                     telomere clustering by binding Sir4p, but is not involved
                     in telomere tethering"
                     /codon_start=1
                     /product="Ebp2p"
                     /protein_id="DAA08994.1"
                     /db_xref="SGD:S000001655"
                     /translation="MAKGFKLKELLSHQKEIEKAEKLENDLKKKKSQELKKEEPTIVT
                     ASNLKKLEKKEKKADVKKEVAADTEEYQSQALSKKEKRKLKKELKKMQEQDATEAQKH
                     MSGDEDESGDDREEEEEEEEEEEGRLDLEKLAKSDSESEDDSESENDSEEDEDVVAKE
                     ESEEKEEQEEEQDVPLSDVEFDSDADVVPHHKLTVNNTKAMKHALERVQLPWKKHSFQ
                     EHQSVTSETNTDEHIKDIYDDTERELAFYKQSLDAVLVARDELKRLKVPFKRPLDYFA
                     EMVKSDEHMDKIKGKLIEEASDKKAREEARRQRQLKKFGKQVQNATLQKRQLEKRETL
                     EKIKSLKNKRKHNEIDHSEFNVGVEEEVEGKRFDRGRPNGKRAAKNAKYGQGGMKRFK
                     RKNDATSSADVSGFSSRKMKGKTNRPGKSRRARRF"
     gene            127475..130261
                     /gene="NNK1"
                     /locus_tag="YKL171W"
     mRNA            127475..130261
                     /gene="NNK1"
                     /locus_tag="YKL171W"
                     /product="protein kinase NNK1"
     CDS             127475..130261
                     /gene="NNK1"
                     /locus_tag="YKL171W"
                     /EC_number="2.7.11.1"
                     /experiment="EXISTENCE:direct assay:GO:0004672 protein
                     kinase activity [PMID:16319894]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:22289182|PMID:11914276]"
                     /experiment="EXISTENCE:direct assay:GO:0006468 protein
                     phosphorylation [PMID:16319894]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006508
                     proteolysis [PMID:11595789]"
                     /note="Protein kinase; implicated in proteasome function;
                     interacts with TORC1, Ure2 and Gdh2; overexpression leads
                     to hypersensitivity to rapamycin and nuclear accumulation
                     of Gln3; epitope-tagged protein localizes to the
                     cytoplasm"
                     /codon_start=1
                     /product="protein kinase NNK1"
                     /protein_id="DAA08995.1"
                     /db_xref="SGD:S000001654"
                     /translation="MFTSQRQLRQNGSPMSSSRSSQHSSGTASPISDSPASNRSYGRD
                     LRGLMGIDIPANEPAFNRANSSDTIYFRPKKIYKMEHEHPSRSTLVQLQTRSQPDDVA
                     SSQVNPEGGTDDLELGDPCGNQSLYTIGAEYVPDLDFTKLVNEWQKSTEDLYEFRSSA
                     TPQVQIKDSGKGNYELWSSPDAILTQNKLRRDSFSQENSDSLSPEDSILSRNLHSKVK
                     PIPLPRNSQQIFTPLSNLEAERRSSYTTSSNNNSITQNNKFSFAKLKYSLPTQSSAVP
                     ASFDSNASSLNFLPTTTLSTLSELQISPNDMMDLIQKLPRNFLNLPYTQRKKVIIEHA
                     PSHDYKAMMSLVKKFMLTSSRSNFSLAGFANNASVSQATANDDNINSRNTPNNSNDTY
                     VNTRPLQRSRHGSIASQFLSSFSPSMTSIAKMNSNPLSGSAGGSARPDDKGMEILGHR
                     LGKIIGFGAWGIIRECFDIETGVGRVIKIVKFKGHQNIKKHVLREVAIWRTLKHNRIL
                     PLLDWKLDDNYAMYCLTERINDGTLYDLVISWDEFKRSKIPFAERCRLTIFLSLQLLS
                     ALKYMHSKTIVHGDIKLENCLLQKEGKKSDWKVFLCDFGMSCHFDEKHVYRNDTFDEN
                     LSSGNSHRKRKSIEQTNLIKYPTTNFLPDDRTNDFDASENLKYQFENRKHQPFTPKGM
                     VSSSSHSLKHLNQPSSSSSSNLFHKPASQPQPQHRSPFHGRHKTTDFSNLEPEPSKYI
                     GSLPYASPELLRYSDARRSKSVEMHIYDSPDSSQSEISAASSSSSNLSSLSSSTKASA
                     VTNSGVTTSSPSGSSTDFPCIVSPLGPASDIWALGVMLYTMLVGKLPFNHEFEPRLRS
                     LIKVGEFDRFSLAQVCKFDRKKNEGTIGQGLYDTVIGCLTIDLDKRWKLKRIEEVLQN
                     EMNLSEAIHDNNGS"
     gene            130634..131050
                     /gene="MRPL38"
                     /locus_tag="YKL170W"
                     /gene_synonym="uL14m"
     mRNA            130634..131050
                     /gene="MRPL38"
                     /locus_tag="YKL170W"
                     /gene_synonym="uL14m"
                     /product="mitochondrial 54S ribosomal protein YmL38/YmL34"
     CDS             130634..131050
                     /gene="MRPL38"
                     /locus_tag="YKL170W"
                     /gene_synonym="uL14m"
                     /experiment="EXISTENCE:curator inference:GO:0032543
                     mitochondrial translation [PMID:12392552|PMID:9151978]"
                     /experiment="EXISTENCE:direct assay:GO:0003735 structural
                     constituent of ribosome [PMID:12392552|PMID:9151978]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005762
                     mitochondrial large ribosomal subunit
                     [PMID:12392552|PMID:9151978]"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit; appears as two protein spots (YmL34 and YmL38) on
                     two-dimensional SDS gels; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein YmL38/YmL34"
                     /protein_id="DAA08996.1"
                     /db_xref="SGD:S000001653"
                     /translation="MIFLKSVIKVIDNSGAQLAECIKVIRKGSPKSPAMVGDRIVCVI
                     QKAKPLTQNITGTANTNRVKKGDICHAIVVRSKQRNMCRKDGSTVAFGDTACVLINKN
                     TGEPLGTRIMANDGCVDRTLKDKGYNKICSLASRVI"
     gene            complement(131288..133462)
                     /gene="KKQ8"
                     /locus_tag="YKL168C"
     mRNA            complement(131288..133462)
                     /gene="KKQ8"
                     /locus_tag="YKL168C"
                     /product="putative serine/threonine protein kinase KKQ8"
     CDS             complement(131288..133462)
                     /gene="KKQ8"
                     /locus_tag="YKL168C"
                     /EC_number="2.7.11.1"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:22289182|PMID:14562095]"
                     /note="Putative serine/threonine protein kinase with
                     unknown cellular role; KKQ8 has a paralog, HAL5, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="putative serine/threonine protein kinase KKQ8"
                     /protein_id="DAA08997.1"
                     /db_xref="SGD:S000001651"
                     /translation="MVMQEEKKRQQPVTRRVRSFSESFKNLFRPPRSRDSSPINVTRI
                     PYRSSSTSPKRSSEPPRRSTVSAQILDPKNSPIRQRSYTLKCCTPGLSHPFRQTGSGA
                     SNSPTRHRSISGEEQEIVNSLPEYKRSASHTFHGIRRPRSRSSSVSSCDSSNGTTSSS
                     DSQWAMDSLLDDSDNDLTPYRGSNKDILKSKDRAPYNYIDDYNKKALRRATSYPNPLP
                     SKQFYNERLYTRRSHPDEESLESLPRFAGADVQCIIEQNGFKVYEDGSHEHNIKLSGV
                     IAKLEKGNSLPAHRQGSLSRPRLGITLSGLFKHHKNECDIENALSLLPNVEKSQTNHE
                     KRTGQSPNDSNRSSPTQGREDYLKIVNPDASLGSDELKLINSLSSRIHKSLQNYLQEK
                     NLKPAECIGEQAPTFQDNYGHPVGLVGAGAYGEVKLCARLRNEKDSPPFETYHDSKYI
                     YYAVKELKPKPDSDLEKFCTKITSEFIIGHSLSHYHKNGKKPAPNILNVFDILEDSSS
                     FIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMKQLLHGVKFMHDHGIAHCDLKP
                     ENILFYPHGLLKICDFGTSSVFQTAWERRVHAQKGIIGSEPYVAPEEFVDGEYYDPRL
                     IDCWSCGVVYITMILGHYLWKVASREKDMSYDEFYKEMQRKNQFRVFEELKHVNSELA
                     TNRKIALYRIFQWEPRKRISVGKLLDMQWMKSTNCCLIYDST"
     gene            complement(133721..134134)
                     /gene="MRP49"
                     /locus_tag="YKL167C"
                     /gene_synonym="mL61"
     mRNA            complement(133721..134134)
                     /gene="MRP49"
                     /locus_tag="YKL167C"
                     /gene_synonym="mL61"
                     /product="mitochondrial 54S ribosomal protein MRP49"
     CDS             complement(133721..134134)
                     /gene="MRP49"
                     /locus_tag="YKL167C"
                     /gene_synonym="mL61"
                     /experiment="EXISTENCE:direct assay:GO:0003735 structural
                     constituent of ribosome [PMID:1544898]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0005762
                     mitochondrial large ribosomal subunit [PMID:1544898]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032543
                     mitochondrial translation [PMID:1544898]"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit; not essential for mitochondrial translation"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein MRP49"
                     /protein_id="DAA08998.1"
                     /db_xref="SGD:S000001650"
                     /translation="MSKVAQQLKFLNKISATTRLPQILVDPKKYSGLRLTFQTKNHNG
                     HMGARVFWHNYLPTLQFYNPRMKFDVIRIKNEDKQKSVPCKLEILSHEGSVVETIDMR
                     NKMHEDIMKDLLDKIEHVPLPENEIIRVGPQESII"
     gene            complement(134509..135705)
                     /gene="TPK3"
                     /locus_tag="YKL166C"
     mRNA            complement(134509..135705)
                     /gene="TPK3"
                     /locus_tag="YKL166C"
                     /product="cAMP-dependent protein kinase catalytic subunit
                     TPK3"
     CDS             complement(134509..135705)
                     /gene="TPK3"
                     /locus_tag="YKL166C"
                     /EC_number="2.7.11.11"
                     /experiment="EXISTENCE:direct assay:GO:0000932 P-body
                     [PMID:22899713]"
                     /experiment="EXISTENCE:direct assay:GO:0004672 protein
                     kinase activity [PMID:16319894]"
                     /experiment="EXISTENCE:direct assay:GO:0004691
                     cAMP-dependent protein kinase activity [PMID:3036373]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:19804918|PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:19804918|PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0006468 protein
                     phosphorylation [PMID:3036373|PMID:16319894]"
                     /experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
                     stress granule [PMID:22899713]"
                     /experiment="EXISTENCE:genetic interaction:GO:0004691
                     cAMP-dependent protein kinase activity [PMID:3036373]"
                     /experiment="EXISTENCE:genetic interaction:GO:0005952
                     cAMP-dependent protein kinase complex [PMID:3036373]"
                     /experiment="EXISTENCE:genetic interaction:GO:0007005
                     mitochondrion organization [PMID:19897478]"
                     /experiment="EXISTENCE:genetic interaction:GO:0007265 Ras
                     protein signal transduction [PMID:3036373]"
                     /experiment="EXISTENCE:genetic interaction:GO:0010607
                     negative regulation of cytoplasmic mRNA processing body
                     assembly [PMID:21925385]"
                     /experiment="EXISTENCE:genetic interaction:GO:0010737
                     protein kinase A signaling [PMID:20133652]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004691
                     cAMP-dependent protein kinase activity [PMID:3036373]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006468 protein
                     phosphorylation [PMID:3036373]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007005
                     mitochondrion organization [PMID:19897478]"
                     /experiment="EXISTENCE:mutant phenotype:GO:2000766
                     negative regulation of cytoplasmic translation
                     [PMID:22899713]"
                     /note="cAMP-dependent protein kinase catalytic subunit;
                     promotes vegetative growth in response to nutrients via
                     the Ras-cAMP signaling pathway; partially redundant with
                     Tpk1p and Tpk2p; localizes to P-bodies during stationary
                     phase; TPK3 has a paralog, TPK1, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="cAMP-dependent protein kinase catalytic subunit
                     TPK3"
                     /protein_id="DAA08999.1"
                     /db_xref="SGD:S000001649"
                     /translation="MYVDPMNNNEIRKLSITAKTETTPDNVGQDIPVNAHSVHEECSS
                     NTPVEINGRNSGKLKEEASAGICLVKKPMLQYRDTSGKYSLSDFQILRTLGTGSFGRV
                     HLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQ
                     VFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENIL
                     LDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEM
                     LAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSE
                     DVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEFNYGIQGEDPYM
                     DLMKEF"
     gene            complement(137932..140691)
                     /gene="MCD4"
                     /locus_tag="YKL165C"
                     /gene_synonym="FSR2"
                     /gene_synonym="SSU21"
                     /gene_synonym="ZRG16"
     mRNA            complement(137932..140691)
                     /gene="MCD4"
                     /locus_tag="YKL165C"
                     /gene_synonym="FSR2"
                     /gene_synonym="SSU21"
                     /gene_synonym="ZRG16"
                     /product="mannose-ethanolamine phosphotransferase MCD4"
     CDS             complement(137932..140691)
                     /gene="MCD4"
                     /locus_tag="YKL165C"
                     /gene_synonym="FSR2"
                     /gene_synonym="SSU21"
                     /gene_synonym="ZRG16"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:10514566]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:10069808|PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0006506 GPI anchor
                     biosynthetic process [PMID:12023081]"
                     /experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
                     cell wall [PMID:12023081]"
                     /experiment="EXISTENCE:direct assay:GO:0015867 ATP
                     transport [PMID:12807869]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006506 GPI
                     anchor biosynthetic process [PMID:16704983|PMID:17311586]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051377
                     mannose-ethanolamine phosphotransferase activity
                     [PMID:16704983|PMID:17311586]"
                     /note="Protein involved in GPI anchor synthesis;
                     multimembrane-spanning protein that localizes to the
                     endoplasmic reticulum; highly conserved among eukaryotes;
                     GPI stands for glycosylphosphatidylinositol"
                     /codon_start=1
                     /product="mannose-ethanolamine phosphotransferase MCD4"
                     /protein_id="DAA09000.1"
                     /db_xref="SGD:S000001648"
                     /translation="MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTP
                     TPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPT
                     ESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGAS
                     DPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFL
                     HLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSA
                     FGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIAS
                     LMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFF
                     YKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTY
                     NWRFIRTIVTFGFVGWIFFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWIL
                     FYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYE
                     GIVYGFFHRWTFTLITNILAFYPFICGVRELSVNILWIITSVLLSTFTLFDAVKIEDL
                     NQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQ
                     GLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFESL
                     FYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASIS
                     SFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIIS
                     MSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKNVIIQDK
                     TKKTQ"
     gene            complement(141018..141089)
                     /locus_tag="YNCK0005C"
     tRNA            complement(141018..141089)
                     /locus_tag="YNCK0005C"
                     /product="tRNA-Glu"
                     /experiment="EXISTENCE:curator inference:GO:0005829
                     cytosol [PMID:9023104]"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /note="Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE
                     analysis; thiolation of uridine at wobble position (34)
                     requires Ncs6p"
                     /db_xref="SGD:S000006558"
     gene            complement(141794..142819)
                     /gene="PIR1"
                     /locus_tag="YKL164C"
                     /gene_synonym="CCW6"
     mRNA            complement(141794..142819)
                     /gene="PIR1"
                     /locus_tag="YKL164C"
                     /gene_synonym="CCW6"
                     /product="beta-1,3-glucan linked protein"
     CDS             complement(141794..142819)
                     /gene="PIR1"
                     /locus_tag="YKL164C"
                     /gene_synonym="CCW6"
                     /experiment="EXISTENCE:direct assay:GO:0005199 structural
                     constituent of cell wall [PMID:9301021]"
                     /experiment="EXISTENCE:direct assay:GO:0005621 cellular
                     bud scar [PMID:16278454]"
                     /experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
                     cell wall [PMID:15781460|PMID:9192695]"
                     /experiment="EXISTENCE:direct assay:GO:0034399 nuclear
                     periphery [PMID:25817432]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006886
                     intracellular protein transport [PMID:11238901]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031505
                     fungal-type cell wall organization [PMID:10407261]"
                     /note="O-glycosylated protein required for cell wall
                     stability; attached to the cell wall via beta-1,3-glucan;
                     mediates mitochondrial translocation of Apn1p; expression
                     regulated by the cell integrity pathway and by Swi5p
                     during the cell cycle; PIR1 has a paralog, YJL160C, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="beta-1,3-glucan linked protein"
                     /protein_id="DAA09001.1"
                     /db_xref="SGD:S000001647"
                     /translation="MQYKKSLVASALVATSLAAYAPKDPWSTLTPSATYKGGITDYSS
                     TFGIAVEPIATTASSKAKRAAAISQIGDGQIQATTKTTAAAVSQIGDGQIQATTKTKA
                     AAVSQIGDGQIQATTKTTSAKTTAAAVSQIGDGQIQATTKTKAAAVSQIGDGQIQATT
                     KTTAAAVSQIGDGQIQATTKTTAAAVSQIGDGQIQATTNTTVAPVSQITDGQIQATTL
                     TSATIIPSPAPAPITNGTDPVTAETCKSSGTLEMNLKGGILTDGKGRIGSIVANRQFQ
                     FDGPPPQAGAIYAAGWSITPEGNLAIGDQDTFYQCLSGNFYNLYDEHIGTQCNAVHLQ
                     AIDLLNC"
     gene            144401..145378
                     /gene="PIR3"
                     /locus_tag="YKL163W"
                     /gene_synonym="CCW8"
     mRNA            144401..145378
                     /gene="PIR3"
                     /locus_tag="YKL163W"
                     /gene_synonym="CCW8"
                     /product="beta-1,3-glucan linked protein"
     CDS             144401..145378
                     /gene="PIR3"
                     /locus_tag="YKL163W"
                     /gene_synonym="CCW8"
                     /experiment="EXISTENCE:direct assay:GO:0005199 structural
                     constituent of cell wall [PMID:10407261]"
                     /experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
                     cell wall [PMID:15781460|PMID:9192695]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031505
                     fungal-type cell wall organization [PMID:10407261]"
                     /note="O-glycosylated covalently-bound cell wall protein;
                     required for cell wall stability; expression is cell cycle
                     regulated, peaking in M/G1 and also subject to regulation
                     by the cell integrity pathway; coding sequence contains
                     length polymorphisms in different strains; PIR3 has a
                     paralog, HSP150, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="beta-1,3-glucan linked protein"
                     /protein_id="DAA09002.1"
                     /db_xref="SGD:S000001646"
                     /translation="MQYKKPLVVSALAATSLAAYAPKDPWSTLTPSATYKGGITDYSS
                     SFGIAIEAVATSASSVASSKAKRAASQIGDGQVQAATTTAAVSKKSTAAAVSQITDGQ
                     VQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAA
                     KSTAAAASQISDGQVQATTSTKAAASQITDGQIQASKTTSGASQVSDGQVQATAEVKD
                     ANDPVDVVSCNNNSTLSMSLSKGILTDRKGRIGSIVANRQFQFDGPPPQAGAIYAAGW
                     SITPEGNLALGDQDTFYQCLSGDFYNLYDKHIGSQCHEVYLQAIDLIDC"
     gene            complement(147630..148838)
                     /locus_tag="YKL162C"
     mRNA            complement(147630..148838)
                     /locus_tag="YKL162C"
                     /product="type II protein arginine methyltransferase"
     CDS             complement(147630..148838)
                     /locus_tag="YKL162C"
                     /EC_number="2.1.1.320"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14562095]"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the mitochondrion"
                     /codon_start=1
                     /product="type II protein arginine methyltransferase"
                     /protein_id="DAA09003.1"
                     /db_xref="SGD:S000001645"
                     /translation="MMKRLHPLRIQVHLKSDYPLFTFEQLLSTNGIRRGQTARISLKD
                     YIEWQNFPNIMKRENFFTQRKPVTTTAKEEPFSFDNILDCEPQFSKCLAKWLLVNYKL
                     NDYPYYDLNIVNIYTDLPQAIQICKNLMSYLKSTLSDNMFQKIKYFMVPLYKCDKIPS
                     KLLDGIPGSVSLVQDYPVSPYFLQKKFHIEDPIQILMLNDVIKYTTHDLVRYSSDDKG
                     WQQCFVDINKNGQKSKSFDSAIDYSCELALEQMFNDRSHVSPGKELYIPTKLIEILMT
                     IKNNIPEHRLFIVDTPQRSSPTIISLLKSLISPRPTGSSQIVQPYSDSIFSDKRSGRI
                     CFMTDFLQLQNIYNGINSSSSSCEVEDVADFVEKWISPSERSTLSSQNGNRPQLEDIK
                     NSSLAVLHST"
     gene            complement(149386..150687)
                     /gene="KDX1"
                     /locus_tag="YKL161C"
                     /gene_synonym="MLP1"
     mRNA            complement(149386..150687)
                     /gene="KDX1"
                     /locus_tag="YKL161C"
                     /gene_synonym="MLP1"
                     /product="putative protein kinase KDX1"
     CDS             complement(149386..150687)
                     /gene="KDX1"
                     /locus_tag="YKL161C"
                     /gene_synonym="MLP1"
                     /EC_number="2.7.11.1"
                     /note="Protein kinase; implicated in Slt2p
                     mitogen-activated (MAP) kinase signaling pathway;
                     interacts with numerous components in the mating pheromone
                     and CWI MAPK pathways; associates with Rlm1p; KDX1 has a
                     paralog, SLT2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="putative protein kinase KDX1"
                     /protein_id="DAA09004.1"
                     /db_xref="SGD:S000001644"
                     /translation="MATDTERCIFRAFGQDFILNKHFHLTGKIGRGSHSLICSSTYTE
                     SNEETHVAIRKIPNAFGNKLSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFYPNGALN
                     GVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLL
                     VNSDCQLKICNFGLSCSYSENHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWS
                     TGCILAELLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIP
                     GRSFESILPGANPEALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEEFSCQKTF
                     RFEFEHIESMAELGNEVIKEVFDFRKVVRKHPISGDSPSSSLSLEDAIPQEVVQVHPS
                     RKVLPSYSPEFSYVSQLPSLTTTQPYQNLMGISSNSFQGVN"
     rep_origin      153020..153135
                     /note="ARS1106; Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118402"
     gene            153269..153706
                     /gene="ELF1"
                     /locus_tag="YKL160W"
     mRNA            153269..153706
                     /gene="ELF1"
                     /locus_tag="YKL160W"
                     /product="Elf1p"
     CDS             153269..153706
                     /gene="ELF1"
                     /locus_tag="YKL160W"
                     /experiment="EXISTENCE:direct assay:GO:0000993 RNA
                     polymerase II complex binding [PMID:20818391]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:19159085|PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0008023
                     transcription elongation factor complex [PMID:20818391]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006368
                     transcription elongation from RNA polymerase II promoter
                     [PMID:16260625]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006368
                     transcription elongation from RNA polymerase II promoter
                     [PMID:16260625]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0048096
                     chromatin-mediated maintenance of transcription
                     [PMID:16260625]"
                     /note="Transcription elongation factor with a conserved
                     zinc finger domain; implicated in the maintenance of
                     proper chromatin structure in actively transcribed
                     regions; deletion inhibits Brome mosaic virus (BMV) gene
                     expression"
                     /codon_start=1
                     /product="Elf1p"
                     /protein_id="DAA09005.1"
                     /db_xref="SGD:S000001643"
                     /translation="MGKRKKSTRKPTKRLVQKLDTKFNCLFCNHEKSVSCTLDKKNSI
                     GTLSCKICGQSFQTRINSLSQPVDVYSDWFDAVEEVNSGRGSDTDDGDEGSDSDYESD
                     SEQDAKTQNDGEIDSDEEEVDSDEERIGQVKRGRGALVDSDDE"
     gene            complement(153816..154451)
                     /gene="RCN1"
                     /locus_tag="YKL159C"
     mRNA            complement(153816..154451)
                     /gene="RCN1"
                     /locus_tag="YKL159C"
                     /product="Rcn1p"
     CDS             complement(153816..154451)
                     /gene="RCN1"
                     /locus_tag="YKL159C"
                     /experiment="EXISTENCE:curator inference:GO:0005737
                     cytoplasm [PMID:10887154]"
                     /experiment="EXISTENCE:direct assay:GO:0030346 protein
                     phosphatase 2B binding [PMID:10887154]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0008597
                     calcium-dependent protein serine/threonine phosphatase
                     regulator activity [PMID:10887154]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0019722
                     calcium-mediated signaling [PMID:17954914]"
                     /note="Protein involved in calcineurin regulation during
                     calcium signaling; has similarity to H. sapiens DSCR1
                     which is found in the Down Syndrome candidate region"
                     /codon_start=1
                     /product="Rcn1p"
                     /protein_id="DAA09006.1"
                     /db_xref="SGD:S000001642"
                     /translation="MGNIITDTIIITSDKCDIVDNDNVERIQVWLSKNILRKFQINEN
                     EPLQLIILKRFKRILLICPSHDISQHVMDASRALEMENFNFSYSLQDGQRNLTKQYLK
                     VPESEKMFLISPPASPPPEFDFSKCEDAPQRHIQSHIQQDQQQRLEASQLLPNNPDKN
                     NNGTFTLLKSKVGAITIDRCPTNDGNGQMQLADHVKTAFPPKSIFDTDDDD"
     gene            154991..158232
                     /gene="APE2"
                     /locus_tag="YKL157W"
                     /gene_synonym="LAP1"
                     /gene_synonym="YKL158W"
     mRNA            join(154991..155271,155655..158232)
                     /gene="APE2"
                     /locus_tag="YKL157W"
                     /gene_synonym="LAP1"
                     /gene_synonym="YKL158W"
                     /product="metallo-aminopeptidase"
     CDS             join(154991..155271,155655..158232)
                     /gene="APE2"
                     /locus_tag="YKL157W"
                     /gene_synonym="LAP1"
                     /gene_synonym="YKL158W"
                     /experiment="EXISTENCE:direct assay:GO:0005576
                     extracellular region [PMID:383482]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0030287 cell
                     wall-bounded periplasmic space [PMID:383482]"
                     /experiment="EXISTENCE:direct assay:GO:0043171 peptide
                     catabolic process [PMID:6352682]"
                     /experiment="EXISTENCE:direct assay:GO:0070006
                     metalloaminopeptidase activity [PMID:6352682]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0043171 peptide
                     catabolic process [PMID:3286257]"
                     /note="Aminopeptidase yscII; may have a role in obtaining
                     leucine from dipeptide substrates; APE2 has a paralog,
                     AAP1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="metallo-aminopeptidase"
                     /protein_id="DAA09007.2"
                     /db_xref="SGD:S000001640"
                     /translation="MPIVRWLLLKSAVRGSSLIGKAHPCLRSIAAHPRYLSNVYSPPA
                     GVSRSLRINVMWKQSKLTPPRFVKIMNRRPLFTETSHACAKCQKTSQLLNKTPNREIL
                     PDNVVPLHYDLTVEPDFKTFKFEGSVKIELKINNPAIDTVTLNTVDTDIHSAKIGDVT
                     SSEIISEEEQQVTTFAFPKGTMSSFKGNAFLDIKFTGILNDNMAGFYRAKYEDKLTGE
                     TKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVKNEYVKDGKK
                     VTLFNTTPKMSTYLVAFIVAELKYVESKNFRIPVRVYATPGNEKHGQFAADLTAKTLA
                     FFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDLLLDKDNSTLDRIQRVAE
                     VVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEWKVWEQYVTDTLQH
                     ALSLDSLRSSHPIEVPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFIKGVSQY
                     LNKFKYGNAKTEDLWDALADASGKDVRSVMNIWTKKVGFPVISVSEDGNGKITFRQNR
                     YLSTADVKPDEDKTIYPVFLALKTKNGVDSSVVLSERSKTIELEDPTFFKVNSEQSGI
                     YITSYTDERWAKLGQQADLLSVEDRVGLVADVKTLSASGYTSTTNFLNLVSKWNNEKS
                     FVVWDQIINSISSMKSTWLFEPKETQDALDNFTKQLISGMTHHLGWEFKSSDSFSTQR
                     LKVTMFGAACAARDADVEKAALKMFTDYCSGNKEAIPALIKPIVFNTVARVGGAENYE
                     KVYKIYLDPISNDEKLAALRSLGRFKEPKLLERTLGYLFDGTVLNQDIYIPMQGMRAH
                     QEGVEALWNWVKKNWDELVKRLPPGLSMLGSVVTLGTSGFTSMQKIDEIKKFFATKST
                     KGFDQSLAQSLDTITSKAQWVNRDRDVVNKYLKENGYY"
     gene            158613..159212
                     /gene="RPS27A"
                     /locus_tag="YKL156W"
     mRNA            join(158613..158615,158967..159212)
                     /gene="RPS27A"
                     /locus_tag="YKL156W"
                     /product="ribosomal 40S subunit protein S27A"
     CDS             join(158613..158615,158967..159212)
                     /gene="RPS27A"
                     /locus_tag="YKL156W"
                     /experiment="EXISTENCE:curator inference:GO:0002181
                     cytoplasmic translation [PMID:3533916]"
                     /experiment="EXISTENCE:direct assay:GO:0003735 structural
                     constituent of ribosome [PMID:3533916]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:11914276]"
                     /experiment="EXISTENCE:direct assay:GO:0022627 cytosolic
                     small ribosomal subunit [PMID:3533916]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000462
                     maturation of SSU-rRNA from tricistronic rRNA transcript
                     (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000028
                     ribosomal small subunit assembly [PMID:9271380]"
                     /note="Protein component of the small (40S) ribosomal
                     subunit; homologous to mammalian ribosomal protein S27, no
                     bacterial homolog; RPS27A has a paralog, RPS27B, that
                     arose from the whole genome duplication; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="ribosomal 40S subunit protein S27A"
                     /protein_id="DAA09008.1"
                     /db_xref="SGD:S000001639"
                     /translation="MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNIT
                     TVFSHAQTAVTCESCSTILCTPTGGKAKLSEGTSFRRK"
     gene            complement(159456..161342)
                     /gene="RSM22"
                     /locus_tag="YKL155C"
     mRNA            complement(159456..161342)
                     /gene="RSM22"
                     /locus_tag="YKL155C"
                     /product="mitochondrial 37S ribosomal protein RSM22"
     CDS             complement(159456..161342)
                     /gene="RSM22"
                     /locus_tag="YKL155C"
                     /experiment="EXISTENCE:curator inference:GO:0032543
                     mitochondrial translation [PMID:11278769]"
                     /experiment="EXISTENCE:direct assay:GO:0003735 structural
                     constituent of ribosome [PMID:11278769]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005763
                     mitochondrial small ribosomal subunit [PMID:11278769]"
                     /note="Mitochondrial ribosomal protein of the small
                     subunit; also predicted to be an
                     S-adenosylmethionine-dependent RNA methyltransferase"
                     /codon_start=1
                     /product="mitochondrial 37S ribosomal protein RSM22"
                     /protein_id="DAA09009.1"
                     /db_xref="SGD:S000001638"
                     /translation="MMKRCFSILPQNVRFSSKFTSLNLPKLDLADFIDSNKRGINVLP
                     SYRDETASTTQATNSKELRLLSKTLQGQSYRDQLELNPDVSKAINNNIMAVHIPNNLR
                     RVATNYYKEIQEPNSLHRPCRTKMEVDAHIASIFLQNYGSIFQSLKELQKRVGPDNFK
                     PQRILDVGYGPATGIVALNDILGPNYRPDLKDAVILGNAEMQERAKIILSRQLNEVVD
                     TVEENVSTEKEQETDRRNKNFQEDEHIGEVMTKKINIMTNLRSSIPASKEYDLIILTH
                     QLLHDGNQFPIQVDENIEHYLNILAPGGHIVIIERGNPMGFEIIARARQITLRPENFP
                     DEFGKIPRPWSRGVTVRGKKDAELGNISSNYFLKVIAPCPHQRKCPLQVGNPNFYTHK
                     EGKDLKFCNFQKSIKRPKFSIELKKGKLLATSWDGSQGNASRLKGTGRRNGRDYEILN
                     YSYLIFERSHKDENTLKEIKKLRNENVNGKYDIGSLGDDTQNSWPRIINDPVKRKGHV
                     MMDLCAPSGELEKWTVSRSFSKQIYHDARKSKKGDLWASAAKTQIKGLGDLNVKKFHK
                     LEKERIKQLKKEERQKARKAMESYNELEDSLQFDDHQFSNFEVMKKLSTFHGNDFLQH
                     VNRK"
     gene            161601..162335
                     /gene="SRP102"
                     /locus_tag="YKL154W"
     mRNA            161601..162335
                     /gene="SRP102"
                     /locus_tag="YKL154W"
                     /product="Signal recognition particle receptor subunit
                     beta"
     CDS             161601..162335
                     /gene="SRP102"
                     /locus_tag="YKL154W"
                     /experiment="EXISTENCE:curator inference:GO:0006614
                     SRP-dependent cotranslational protein targeting to
                     membrane [PMID:7844142]"
                     /experiment="EXISTENCE:direct assay:GO:0030176 integral
                     component of endoplasmic reticulum membrane
                     [PMID:9679135]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005047 signal
                     recognition particle binding [PMID:9679135]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045047 protein
                     targeting to ER [PMID:9679135]"
                     /experiment="EXISTENCE:physical interaction:GO:0005785
                     signal recognition particle receptor complex
                     [PMID:9679135]"
                     /note="Signal recognition particle (SRP) receptor beta
                     subunit; involved in SRP-dependent protein targeting;
                     anchors the alpha subunit, Srp101p to the ER membrane"
                     /codon_start=1
                     /product="Signal recognition particle receptor subunit
                     beta"
                     /protein_id="DAA09010.1"
                     /db_xref="SGD:S000001637"
                     /translation="MLSNTLIIACLLVIGTTIALIAVQKASSKTGIKQKSYQPSIIIA
                     GPQNSGKTSLLTLLTTDSVRPTVVSQEPLSAADYDGSGVTLVDFPGHVKLRYKLSDYL
                     KTRAKFVKGLIFMVDSTVDPKKLTTTAEFLVDILSITESSCENGIDILIACNKSELFT
                     ARPPSKIKDALESEIQKVIERRKKSLNEVERKINEEDYAENTLDVLQSTDGFKFANLE
                     ASVVAFEGSINKRKISQWREWIDEKL"
     gene            complement(162487..162558)
                     /locus_tag="YNCK0006C"
     tRNA            complement(162487..162558)
                     /locus_tag="YNCK0006C"
                     /product="tRNA-Arg"
                     /experiment="EXISTENCE:curator inference:GO:0005829
                     cytosol [PMID:9023104]"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /note="Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE
                     analysis; one of 11 nuclear tRNA genes containing the
                     tDNA-anticodon UCU (converted to mcm5-UCU in the mature
                     tRNA), decodes AGA codons into arginine, one of 19 nuclear
                     tRNAs for arginine"
                     /db_xref="SGD:S000006716"
     repeat_region   162831..163169
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000007056"
     gene            complement(163642..164385)
                     /gene="GPM1"
                     /locus_tag="YKL152C"
     mRNA            complement(163642..164385)
                     /gene="GPM1"
                     /locus_tag="YKL152C"
                     /product="phosphoglycerate mutase GPM1"
     CDS             complement(163642..164385)
                     /gene="GPM1"
                     /locus_tag="YKL152C"
                     /EC_number="5.4.2.11"
                     /experiment="EXISTENCE:direct assay:GO:0004619
                     phosphoglycerate mutase activity [PMID:1386023]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16962558|PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005758
                     mitochondrial intermembrane space [PMID:22984289]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:3332961]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004619
                     phosphoglycerate mutase activity [PMID:3033435]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006094
                     gluconeogenesis [PMID:3033435]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006096
                     glycolytic process [PMID:11015729]"
                     /note="Tetrameric phosphoglycerate mutase; mediates the
                     conversion of 3-phosphoglycerate to 2-phosphoglycerate
                     during glycolysis and the reverse reaction during
                     gluconeogenesis"
                     /codon_start=1
                     /product="phosphoglycerate mutase GPM1"
                     /protein_id="DAA09011.1"
                     /db_xref="SGD:S000001635"
                     /translation="MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLK
                     EKKVYPDVLYTSKLSRAIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETL
                     KKFGEEKFNTYRRSFDVPPPPIDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLL
                     PYWQDVIAKDLLSGKTVMIAAHGNSLRGLVKHLEGISDADIAKLNIPTGIPLVFELDE
                     NLKPSKPSYYLDPEAAAAGAAAVANQGKK"
     gene            complement(164917..165930)
                     /gene="NNR2"
                     /locus_tag="YKL151C"
     mRNA            complement(164917..165930)
                     /gene="NNR2"
                     /locus_tag="YKL151C"
                     /product="NADHX dehydratase"
     CDS             complement(164917..165930)
                     /gene="NNR2"
                     /locus_tag="YKL151C"
                     /EC_number="4.2.1.93"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0046496
                     nicotinamide nucleotide metabolic process [PMID:21994945]"
                     /experiment="EXISTENCE:direct assay:GO:0047453
                     ATP-dependent NAD(P)H-hydrate dehydratase activity
                     [PMID:21994945]"
                     /note="Widely-conserved NADHX dehydratase; converts
                     (S)-NADHX to NADH in ATP-dependent manner; YKL151C
                     promoter contains STREs (stress response elements) and
                     expression is induced by heat shock or methyl
                     methanesulfonate; downstream intergenic region drives
                     antisense expression and mediates coordinated regulation
                     of YKL151C and GPM1 phosphoglycerate mutase; protein
                     abundance increases in response to DNA replication stress;
                     homolog of Carkd in mammals and C-terminus of YjeF in
                     E.coli"
                     /codon_start=1
                     /product="NADHX dehydratase"
                     /protein_id="DAA09012.1"
                     /db_xref="SGD:S000001634"
                     /translation="MLAELSHRELIKLAQKRCIPPLLPKFHKGQSGGRVCIIGGCEDY
                     TGAPYFSANATALMGCDLTHVICEYNAGTVIKSYTPNLMVHPYLRMSNTKLDVDMDEQ
                     RKKINSLLDRIHVVVIGPGLGRDPLMLKSIKDIIRYILEKHEGKIPLVIDADGLFLVT
                     QDSEVKEMLKSYPKGRVILTPNVVEFKRLCDAIGKKGDSHSEMGSLIAQELNCIVVEK
                     GQSDKIFSPDSEKDMLTNSEEGSNKRVGGQGDTLTGAISCMLAFSRAMYDFKICEQEE
                     KGESSNDKPLKNWVDYAMLSCYAGCTITRECSRLGFKAKGRAMQTTDLNDRVGEVFAK
                     LFG"
     gene            166544..167452
                     /gene="MCR1"
                     /locus_tag="YKL150W"
     mRNA            166544..167452
                     /gene="MCR1"
                     /locus_tag="YKL150W"
                     /product="cytochrome-b5 reductase"
     CDS             166544..167452
                     /gene="MCR1"
                     /locus_tag="YKL150W"
                     /EC_number="1.6.2.2"
                     /experiment="EXISTENCE:direct assay:GO:0004128
                     cytochrome-b5 reductase activity, acting on NAD(P)H
                     [PMID:8001120]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005741
                     mitochondrial outer membrane [PMID:8001120|PMID:16407407]"
                     /experiment="EXISTENCE:direct assay:GO:0005758
                     mitochondrial intermembrane space [PMID:8001120]"
                     /experiment="EXISTENCE:direct assay:GO:0006696 ergosterol
                     biosynthetic process [PMID:10622712]"
                     /experiment="EXISTENCE:direct assay:GO:0031307 integral
                     component of mitochondrial outer membrane [PMID:16689936]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0034599
                     cellular response to oxidative stress [PMID:11420140]"
                     /note="Mitochondrial NADH-cytochrome b5 reductase;
                     involved in ergosterol biosynthesis"
                     /codon_start=1
                     /product="cytochrome-b5 reductase"
                     /protein_id="DAA09013.1"
                     /db_xref="SGD:S000001633"
                     /translation="MFSRLSRSHSKALPIALGTVAIAAATAFYFANRNQHSFVFNESN
                     KVFKGDDKWIDLPISKIEEESHDTRRFTFKLPTEDSEMGLVLASALFAKFVTPKGSNV
                     VRPYTPVSDLSQKGHFQLVVKHYEGGKMTSHLFGLKPNDTVSFKGPIMKWKWQPNQFK
                     SITLLGAGTGINPLYQLAHHIVENPNDKTKVNLLYGNKTPQDILLRKELDALKEKYPD
                     KFNVTYFVDDKQDDQDFDGEISFISKDFIQEHVPGPKESTHLFVCGPPPFMNAYSGEK
                     KSPKDQGELIGILNNLGYSKDQVFKF"
     gene            complement(167612..168829)
                     /gene="DBR1"
                     /locus_tag="YKL149C"
                     /gene_synonym="PRP26"
     mRNA            complement(167612..168829)
                     /gene="DBR1"
                     /locus_tag="YKL149C"
                     /gene_synonym="PRP26"
                     /product="RNA lariat debranching enzyme"
     CDS             complement(167612..168829)
                     /gene="DBR1"
                     /locus_tag="YKL149C"
                     /gene_synonym="PRP26"
                     /experiment="EXISTENCE:curator inference:GO:0005634
                     nucleus [PMID:1850323]"
                     /experiment="EXISTENCE:direct assay:GO:0006401 RNA
                     catabolic process [PMID:1850323]"
                     /experiment="EXISTENCE:direct assay:GO:0008419 RNA lariat
                     debranching enzyme activity [PMID:1850323]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000398 mRNA
                     splicing, via spliceosome [PMID:24919400]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006401 RNA
                     catabolic process [PMID:1850323]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007124
                     pseudohyphal growth [PMID:9055077]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0008419 RNA
                     lariat debranching enzyme activity [PMID:1850323]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016074
                     sno(s)RNA metabolic process [PMID:9740128]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032197
                     transposition, RNA-mediated [PMID:10652222]"
                     /note="RNA lariat debranching enzyme; catalyzes
                     debranching of lariat introns formed during pre-mRNA
                     splicing; required for efficient Ty1 transposition;
                     knockdown of human homolog Dbr1 rescues toxicity of
                     RNA-binding proteins TDP-43 and FUS which are implicated
                     in amyotrophic lateral sclerosis (ALS), suggests potential
                     therapeutic target for ALS and related TDP-43
                     proteinopathies; human homolog DBR1 can complement yeast
                     dbr1 null mutant"
                     /codon_start=1
                     /product="RNA lariat debranching enzyme"
                     /protein_id="DAA09014.1"
                     /db_xref="SGD:S000001632"
                     /translation="MTKLRIAVQGCCHGQLNQIYKEVSRIHAKTPIDLLIILGDFQSI
                     RDGQDFKSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGYVA
                     KNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKANIRNLYHVRI
                     SDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPFFEQDIKEGKLGSPVTWQL
                     LRDLRPQWWLSAHLHVRFMASIKHNKRSHEPPNKSTSKTKKNNNEIDLDLSSDEDERS
                     GIMNCQEENEYDSKYGETRFLALDKCLPRRRWLEILEIEPDTSHASWKDENHRMFWDP
                     EFINNLVICQKNKNLLSNKPFNSVNWIELSQSNREEGRDIDWENYAIPAYTLDIQKDE
                     VRQTKAFISKFMT"
     gene            complement(169207..171129)
                     /gene="SDH1"
                     /locus_tag="YKL148C"
     mRNA            complement(169207..171129)
                     /gene="SDH1"
                     /locus_tag="YKL148C"
                     /product="succinate dehydrogenase flavoprotein subunit
                     SDH1"
     CDS             complement(169207..171129)
                     /gene="SDH1"
                     /locus_tag="YKL148C"
                     /EC_number="1.3.5.1"
                     /experiment="EXISTENCE:curator inference:GO:0006099
                     tricarboxylic acid cycle [PMID:13445213]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:2826438|PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005749
                     mitochondrial respiratory chain complex II, succinate
                     dehydrogenase complex (ubiquinone) [PMID:9822678]"
                     /experiment="EXISTENCE:direct assay:GO:0006121
                     mitochondrial electron transport, succinate to ubiquinone
                     [PMID:2826438]"
                     /experiment="EXISTENCE:direct assay:GO:0008177 succinate
                     dehydrogenase (ubiquinone) activity [PMID:13445213]"
                     /experiment="EXISTENCE:direct assay:GO:0031966
                     mitochondrial membrane [PMID:1939170]"
                     /experiment="EXISTENCE:direct assay:GO:0050660 flavin
                     adenine dinucleotide binding [PMID:18279395]"
                     /experiment="EXISTENCE:genetic interaction:GO:0008177
                     succinate dehydrogenase (ubiquinone) activity
                     [PMID:16232921]"
                     /experiment="EXISTENCE:genetic interaction:GO:0045333
                     cellular respiration [PMID:16232921|PMID:9730279]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0008177
                     succinate dehydrogenase (ubiquinone) activity
                     [PMID:16232921|PMID:197391|PMID:9730279]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045333
                     cellular respiration [PMID:16232921|PMID:9730279]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0050660 flavin
                     adenine dinucleotide binding [PMID:1939170]"
                     /note="Flavoprotein subunit of succinate dehydrogenase;
                     couples the oxidation of succinate to the transfer of
                     electrons to ubiquinone as part of the TCA cycle and the
                     mitochondrial respiratory chain; FAD binding to Sdh1p is
                     required for the assembly of the succinate dehydrogenase
                     subunits; mutations in human ortholog SDHA are associated
                     with Leigh syndrome and predisposition to several cancers"
                     /codon_start=1
                     /product="succinate dehydrogenase flavoprotein subunit
                     SDH1"
                     /protein_id="DAA09015.1"
                     /db_xref="SGD:S000001631"
                     /translation="MLSLKKSALSKLTLLRNTRTFTSSALVRQTQGSVNGSASRSADG
                     KYHIIDHEYDCVVIGAGGAGLRAAFGLAEAGYKTACISKLFPTRSHTVAAQGGINAAL
                     GNMHKDNWKWHMYDTVKGSDWLGDQDSIHYMTREAPKSIIELEHYGVPFSRTENGKIY
                     QRAFGGQTKEYGKGAQAYRTCAVADRTGHALLHTLYGQALRHDTHFFIEYFALDLLTH
                     NGEVVGVIAYNQEDGTIHRFRAHKTIIATGGYGRAYFSCTSAHTCTGDGNAMVSRAGF
                     PLQDLEFVQFHPSGIYGSGCLITEGARGEGGFLVNSEGERFMERYAPTAKDLACRDVV
                     SRAITMEIREGRGVGKKKDHMYLQLSHLPPEVLKERLPGISETAAIFAGVDVTKEPIP
                     IIPTVHYNMGGIPTKWNGEALTIDEETGEDKVIPGLMACGEAACVSVHGANRLGANSL
                     LDLVVFGRAVAHTVADTLQPGLPHKPLPSDLGKESIANLDKLRNANGSRSTAEIRMNM
                     KQTMQKDVSVFRTQSSLDEGVRNITAVEKTFDDVKTTDRSMIWNSDLVETLELQNLLT
                     CASQTAVSAANRKESRGAHAREDYPNRDDEHWMKHTLSWQKDVAAPVTLKYRRVIDHT
                     LDEKECPSVPPTVRAY"
     gene            171783..173861
                     /gene="AVT3"
                     /locus_tag="YKL146W"
     mRNA            171783..173861
                     /gene="AVT3"
                     /locus_tag="YKL146W"
                     /product="Avt3p"
     CDS             171783..173861
                     /gene="AVT3"
                     /locus_tag="YKL146W"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:27246536]"
                     /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
                     vacuole membrane [PMID:26928762]"
                     /experiment="EXISTENCE:genetic interaction:GO:0005302
                     L-tyrosine transmembrane transporter activity
                     [PMID:11274162]"
                     /experiment="EXISTENCE:genetic interaction:GO:0015186
                     L-glutamine transmembrane transporter activity
                     [PMID:11274162]"
                     /experiment="EXISTENCE:genetic interaction:GO:0015188
                     L-isoleucine transmembrane transporter activity
                     [PMID:11274162]"
                     /experiment="EXISTENCE:genetic interaction:GO:0032974
                     amino acid transmembrane export from vacuole
                     [PMID:11274162]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000329
                     fungal-type vacuole membrane [PMID:11274162]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005302
                     L-tyrosine transmembrane transporter activity
                     [PMID:11274162]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015186
                     L-glutamine transmembrane transporter activity
                     [PMID:11274162]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015188
                     L-isoleucine transmembrane transporter activity
                     [PMID:11274162]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015824 proline
                     transport [PMID:27246536]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032974 amino
                     acid transmembrane export from vacuole [PMID:11274162]"
                     /note="Vacuolar transporter; exports large neutral amino
                     acids from the vacuole; member of a family of seven S.
                     cerevisiae genes (AVT1-7) related to vesicular
                     GABA-glycine transporters"
                     /codon_start=1
                     /product="Avt3p"
                     /protein_id="DAA09016.1"
                     /db_xref="SGD:S000001629"
                     /translation="MNGKEVSSGSGRTQSNNNKKNNNGGSTGISHASGSPLTDGNGGN
                     SNGNSRSRSRSRKSSGTTGGLLKKPPLLVNNEAVHASVPDASHTSCNNGTLEVSINNP
                     EPHVVDAVARHLIRNPSNSLQLQGGDITRDLYKWTNDHPSSPSQYQYPSQPALSTSIP
                     SQAPSFSNRKRSMSFSAASIASSSHLNNNSEANGNPLAAIGLAPAPMTHEEIRAPGGF
                     RRSFIIQKRRKHNVDAPIPNFFTRNFIEFLTLYGHFAGEDLSEEEEEEEETEEEPEEE
                     ALETESTQLVSREHGRHPHKSSTVKAVLLLLKSFVGTGVLFLPKAFHNGGWGFSALCL
                     LSCALISYGCFVSLITTKDKVGVDGYGDMGRILYGPKMKFAILSSIALSQIGFSAAYT
                     VFTATNLQVFSENFFHLKPGSISLATYIFAQVLIFVPLSLTRNIAKLSGTALIADLFI
                     LLGLVYVYVYSIYYIAVNGVASDTMLMFNKADWSLFIGTAIFTFEGIGLLIPIQESMK
                     HPKHFRPSLSAVMCIVAVIFISCGLLCYAAFGSDVKTVVLLNFPQDTSYTLTVQLLYA
                     LAILLSTPLQLFPAIRILENWTFPSNASGKYNPKVKWLKNYFRCAIVVLTSILAWVGA
                     NDLDKFVSLVGSFACIPLIYIYPPLLHYKASILSGTSRARLLLDLIVIVFGVAVMAYT
                     SWQTIKMWSQ"
     gene            174213..175616
                     /gene="RPT1"
                     /locus_tag="YKL145W"
                     /gene_synonym="CIM5"
                     /gene_synonym="YTA3"
     mRNA            174213..175616
                     /gene="RPT1"
                     /locus_tag="YKL145W"
                     /gene_synonym="CIM5"
                     /gene_synonym="YTA3"
                     /product="proteasome regulatory particle base subunit
                     RPT1"
     CDS             174213..175616
                     /gene="RPT1"
                     /locus_tag="YKL145W"
                     /gene_synonym="CIM5"
                     /gene_synonym="YTA3"
                     /experiment="EXISTENCE:direct assay:GO:0008540 proteasome
                     regulatory particle, base subcomplex [PMID:9741626]"
                     /experiment="EXISTENCE:direct assay:GO:0045732 positive
                     regulation of protein catabolic process [PMID:15135049]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045899
                     positive regulation of RNA polymerase II transcription
                     preinitiation complex assembly [PMID:19843524]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0070682
                     proteasome regulatory particle assembly [PMID:19412160]"
                     /experiment="EXISTENCE:physical interaction:GO:0006511
                     ubiquitin-dependent protein catabolic process
                     [PMID:15135049]"
                     /experiment="EXISTENCE:physical interaction:GO:0031625
                     ubiquitin protein ligase binding [PMID:10688918]"
                     /note="ATPase of the 19S regulatory particle of the 26S
                     proteasome; one of six ATPases of the regulatory particle;
                     involved in the degradation of ubiquitinated substrates;
                     required for optimal CDC20 transcription; interacts with
                     Rpn12p and Ubr1p; mutant has aneuploidy tolerance"
                     /codon_start=1
                     /product="proteasome regulatory particle base subunit
                     RPT1"
                     /protein_id="DAA09017.1"
                     /db_xref="SGD:S000001628"
                     /translation="MPPKEDWEKYKAPLEDDDKKPDDDKIVPLTEGDIQVLKSYGAAP
                     YAAKLKQTENDLKDIEARIKEKAGVKESDTGLAPSHLWDIMGDRQRLGEEHPLQVARC
                     TKIIKGNGESDETTTDNNNSGNSNSNSNQQSTDADEDDEDAKYVINLKQIAKFVVGLG
                     ERVSPTDIEEGMRVGVDRSKYNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQI
                     EKLREVVELPLLSPERFATLGIDPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIG
                     SELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFDDGAGGDNEVQRTML
                     ELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVEFSLPDLEGRANIFRIH
                     SKSMSVERGIRWELISRLCPNSTGAELRSVCTEAGMFAIRARRKVATEKDFLKAVDKV
                     ISGYKKFSSTSRYMQYN"
     gene            complement(175843..176481)
                     /gene="RPC25"
                     /locus_tag="YKL144C"
                     /gene_synonym="YKL1"
     mRNA            complement(175843..176481)
                     /gene="RPC25"
                     /locus_tag="YKL144C"
                     /gene_synonym="YKL1"
                     /product="DNA-directed RNA polymerase III subunit RPC25"
     CDS             complement(175843..176481)
                     /gene="RPC25"
                     /locus_tag="YKL144C"
                     /gene_synonym="YKL1"
                     /experiment="EXISTENCE:direct assay:GO:0001056 RNA
                     polymerase III activity [PMID:3905793]"
                     /experiment="EXISTENCE:direct assay:GO:0005666 RNA
                     polymerase III complex [PMID:10611227|PMID:3905793]"
                     /experiment="EXISTENCE:direct assay:GO:0042797 tRNA
                     transcription by RNA polymerase III [PMID:3905793]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006384
                     transcription initiation from RNA polymerase III promoter
                     [PMID:15612920]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042797 tRNA
                     transcription by RNA polymerase III
                     [PMID:15612920|PMID:8065349]"
                     /note="RNA polymerase III subunit C25; required for
                     transcription initiation; forms a heterodimer with Rpc17p;
                     paralog of Rpb7p"
                     /codon_start=1
                     /product="DNA-directed RNA polymerase III subunit RPC25"
                     /protein_id="DAA09018.1"
                     /db_xref="SGD:S000001627"
                     /translation="MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGL
                     CITIYDLLTVEEGQLKPGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLL
                     GIFDDIFIPQNMLFEGCYYTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVFVDVKP
                     KSPKERELEERAQLENEIEGKNEETPQNEKPPAYALLGSCQTDGMGLVSWWE"
     gene            176781..178172
                     /gene="LTV1"
                     /locus_tag="YKL143W"
                     /gene_synonym="YKL2"
     mRNA            176781..178172
                     /gene="LTV1"
                     /locus_tag="YKL143W"
                     /gene_synonym="YKL2"
                     /product="Ltv1p"
     CDS             176781..178172
                     /gene="LTV1"
                     /locus_tag="YKL143W"
                     /gene_synonym="YKL2"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:16888326]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:16888326|PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0030688
                     preribosome, small subunit precursor
                     [PMID:16738661|PMID:15167894]"
                     /experiment="EXISTENCE:direct assay:GO:0031902 late
                     endosome membrane [PMID:16732272]"
                     /experiment="EXISTENCE:direct assay:GO:0071986 Ragulator
                     complex [PMID:16732272]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000056
                     ribosomal small subunit export from nucleus
                     [PMID:16888326]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000056
                     ribosomal small subunit export from nucleus
                     [PMID:16888326]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006970
                     response to osmotic stress [PMID:15611164]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0034599
                     cellular response to oxidative stress [PMID:15611164]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042274
                     ribosomal small subunit biogenesis [PMID:15611164]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1904669 ATP
                     export [PMID:26585826]"
                     /note="Subunit of the EGO/GSE complex; the
                     vacuolar/endosomal membrane associated EGO/GSE complex
                     regulates exit from rapamycin-induced growth arrest,
                     stimulating microautophagy and sorting of Gap1p from the
                     endosome to the plasma membrane; required for ribosomal
                     small subunit export from nucleus; required for growth at
                     low temperature"
                     /codon_start=1
                     /product="Ltv1p"
                     /protein_id="DAA09019.1"
                     /db_xref="SGD:S000001626"
                     /translation="MSKKFSSKNSQRYVVVHRPHDDPSFYDTDASAHVLVPVSNPNKT
                     SPEADLRKKDVSSTKPKGRRAHVGEAALYGINFDDSEYDYTQHLKPIGLDPENSIFIA
                     SKGNEQKVEKKNIEDLFIEPKYRRDEIEKDDALPVFQRGMAKPEYLLHQQDTTDEIRG
                     FKPDMNPALREVLEALEDEAYVVNDDVVVEDISKKTQLQGDNYGEEEKEDDIFAQLLG
                     SGEAKDEDEFEDEFDEWDIDNVENFEDENYVKEMAQFDNIENLEDLENIDYQADVRRF
                     QKDNSILEKHNSDDEFSNAGLDSVNPSEEEDVLGELPSIQDKSKTGKKKRKSRQKKGA
                     MSDVSGFSMSSSAIARTETMTVLDDQYDQIINGYENYEEELEEDEEQNYQPFDMSAER
                     SDFESMLDDFLDNYELESGGRKLAKKDKEIERLKEAADEVSKGKLSQRRNRERQEKKK
                     LEKVTNTLSSLKF"
     gene            178515..179174
                     /gene="MRP8"
                     /locus_tag="YKL142W"
                     /gene_synonym="YKL3"
     mRNA            178515..179174
                     /gene="MRP8"
                     /locus_tag="YKL142W"
                     /gene_synonym="YKL3"
                     /product="Mrp8p"
     CDS             178515..179174
                     /gene="MRP8"
                     /locus_tag="YKL142W"
                     /gene_synonym="YKL3"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /note="hypothetical protein; undergoes sumoylation;
                     transcription induced under cell wall stress; protein
                     levels are reduced under anaerobic conditions; protein
                     abundance increases in response to DNA replication stress;
                     originally thought to be a mitochondrial ribosomal protein
                     based on sequence analysis"
                     /codon_start=1
                     /product="Mrp8p"
                     /protein_id="DAA09020.1"
                     /db_xref="SGD:S000001625"
                     /translation="MSNEIELLQKQVSELQDLVKKQSLIISKTGERVLELQLDKQKHD
                     VTDFDSKFSKSISKKSGSATQFDATDFATNEDLVELVKELQGELNFIEERSIRRLVNS
                     LKKDDDDVIAPLPNADGDIPAISDGVFPKSLKEFKDIPDLKLVRLAKFYERLPPTLKE
                     QEDFENFLEGKVEAFHINETTDEEISKELEKFSKDELDDAFNDVARYLGLSLRRGTEI
                     W"
     gene            179667..180263
                     /gene="SDH3"
                     /locus_tag="YKL141W"
                     /gene_synonym="CYB3"
                     /gene_synonym="YKL4"
     mRNA            179667..180263
                     /gene="SDH3"
                     /locus_tag="YKL141W"
                     /gene_synonym="CYB3"
                     /gene_synonym="YKL4"
                     /product="succinate dehydrogenase cytochrome b subunit
                     SDH3"
     CDS             179667..180263
                     /gene="SDH3"
                     /locus_tag="YKL141W"
                     /gene_synonym="CYB3"
                     /gene_synonym="YKL4"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005749
                     mitochondrial respiratory chain complex II, succinate
                     dehydrogenase complex (ubiquinone)
                     [PMID:22152483|PMID:9822678]"
                     /experiment="EXISTENCE:direct assay:GO:0042721 TIM22
                     mitochondrial import inner membrane insertion complex
                     [PMID:22152483]"
                     /experiment="EXISTENCE:genetic interaction:GO:0008177
                     succinate dehydrogenase (ubiquinone) activity
                     [PMID:18028869]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045039 protein
                     insertion into mitochondrial inner membrane
                     [PMID:22152483]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045333
                     cellular respiration [PMID:16232921]"
                     /note="Subunit of succinate dehydrogenase and of TIM22
                     translocase; functions as cytochrome b subunit of
                     succinate dehydrogenase, which couples oxidation of
                     succinate to transfer of electrons to ubiquinone as part
                     of the TCA cycle and the mitochondrial respiratory chain;
                     also required for mitochondrial inner membrane protein
                     import as part of the TIM22 complex; SDH3 has a paralog,
                     SHH3, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="succinate dehydrogenase cytochrome b subunit
                     SDH3"
                     /protein_id="DAA09021.1"
                     /db_xref="SGD:S000001624"
                     /translation="MSAMMVKLGLNKSALLLKPSAFSRAAALSSSRRLLFNTARTNFL
                     STSPLKNVASEMNTKAAIAEEQILNKQRAKRPISPHLTIYQPQLTWYLSSLHRISLVL
                     MGLGFYLFTILFGVSGLLGLGLTTEKVSNWYHQKFSKITEWSIKGSFAYLFAIHYGGA
                     IRHLIWDTAKELTLKGVYRTGYALIGFTAVLGTYLLTL"
     gene            180779..182425
                     /gene="TGL1"
                     /locus_tag="YKL140W"
                     /gene_synonym="YKL5"
     mRNA            180779..182425
                     /gene="TGL1"
                     /locus_tag="YKL140W"
                     /gene_synonym="YKL5"
                     /product="sterol esterase"
     CDS             180779..182425
                     /gene="TGL1"
                     /locus_tag="YKL140W"
                     /gene_synonym="YKL5"
                     /EC_number="3.1.1.13"
                     /experiment="EXISTENCE:direct assay:GO:0004771 sterol
                     esterase activity [PMID:15713625]"
                     /experiment="EXISTENCE:direct assay:GO:0005811 lipid
                     droplet [PMID:10515935|PMID:15713625|PMID:24868093]"
                     /experiment="EXISTENCE:direct assay:GO:0016021 integral
                     component of membrane [PMID:15713625]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016125 sterol
                     metabolic process [PMID:15713625]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0044255
                     cellular lipid metabolic process [PMID:10515935]"
                     /note="Steryl ester hydrolase; one of three gene products
                     (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester
                     hydrolase activity and involved in sterol homeostasis;
                     localized to lipid particle membranes"
                     /codon_start=1
                     /product="sterol esterase"
                     /protein_id="DAA09022.1"
                     /db_xref="SGD:S000001623"
                     /translation="MYFPFLGRLSITDYIIVVLVYIESIISSVLKLIPQPMINLFEWL
                     INFSTSSDDNTIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNR
                     FNNKVVYLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKP
                     PKSNKFWDFSIDEFAFFDIPNSIEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLN
                     RKVSHFIAIAPAMTPKGLHNRIVDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTLHPTL
                     FNLCIDIANKILFNWKSFNILPRQKIASYAKLYSTTSVKSIVHWFQILRSQKFQMFEE
                     SDNMLNSLTRPYQIANFPTRTNIKIPILLIYGGIDSLVDIDVMKKNLPFNSVFDVKVD
                     NYEHLDLIWGKDADTLVIAKVLRFIEFFNPGNVSVKTNQLLPSASLVEELPSTTWKTT
                     HPTHGLSYRTHSADRSPLSVQADEADEVHNADNSRFLRRVFSTSAIDEDNENEHQDDT
                     EDQIHKEQQRRLSAYLESSKDLRQLDANSSTTALDALNKE"
     gene            182958..184544
                     /gene="CTK1"
                     /locus_tag="YKL139W"
     mRNA            182958..184544
                     /gene="CTK1"
                     /locus_tag="YKL139W"
                     /product="cyclin-dependent serine/threonine protein kinase
                     CTK1"
     CDS             182958..184544
                     /gene="CTK1"
                     /locus_tag="YKL139W"
                     /EC_number="2.7.11.23"
                     /experiment="EXISTENCE:direct assay:GO:0004672 protein
                     kinase activity [PMID:16319894]"
                     /experiment="EXISTENCE:direct assay:GO:0004693
                     cyclin-dependent protein serine/threonine kinase activity
                     [PMID:7565723]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:9110987]"
                     /experiment="EXISTENCE:direct assay:GO:0005654 nucleoplasm
                     [PMID:15520468]"
                     /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
                     [PMID:15520468]"
                     /experiment="EXISTENCE:direct assay:GO:0006468 protein
                     phosphorylation [PMID:16319894]"
                     /experiment="EXISTENCE:direct assay:GO:0018105
                     peptidyl-serine phosphorylation [PMID:17545469]"
                     /experiment="EXISTENCE:direct assay:GO:0032786 positive
                     regulation of DNA-templated transcription, elongation
                     [PMID:9110987]"
                     /experiment="EXISTENCE:direct assay:GO:0070692 CTDK-1
                     complex [PMID:7565723]"
                     /experiment="EXISTENCE:genetic interaction:GO:0031124 mRNA
                     3'-end processing [PMID:12504017]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006413
                     translational initiation [PMID:25416238]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006468 protein
                     phosphorylation [PMID:1820212]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031124 mRNA
                     3'-end processing [PMID:12504017]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045903
                     positive regulation of translational fidelity
                     [PMID:17545469]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045943
                     positive regulation of transcription by RNA polymerase I
                     [PMID:15520468]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0070816
                     phosphorylation of RNA polymerase II C-terminal domain
                     [PMID:19328068]"
                     /note="Catalytic (alpha) subunit of C-terminal domain
                     kinase I (CTDK-I); phosphorylates both RNA pol II subunit
                     Rpo21p to affect transcription and pre-mRNA 3' end
                     processing, and ribosomal protein Rps2p to increase
                     translational fidelity; required for H3K36 trimethylation
                     but not dimethylation by Set2p; suggested stimulatory role
                     in 80S formation during translation initiation; similar to
                     the Drosophila dCDK12 and human CDK12 and probably CDK13"
                     /codon_start=1
                     /product="cyclin-dependent serine/threonine protein kinase
                     CTK1"
                     /protein_id="DAA09023.1"
                     /db_xref="SGD:S000001622"
                     /translation="MSYNNGNTYSKSYSRNNKRPLFGKRSPNPQSLARPPPPKRIRTD
                     SGYQSNMDNISSHRVNSNDQPGHTKSRGNNNLSRYNDTSFQTSSRYQGSRYNNNNTSY
                     ENRPKSIKRDETKAEFLSHLPKGPKSVEKSRYNNSSNTSNDIKNGYHASKYYNHKGQE
                     GRSVIAKKVPVSVLTQQRSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQG
                     EREGFPITSIREIKLLQSFDHPNVSTIKEIMVESQKTVYMIFEYADNDLSGLLLNKEV
                     QISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLARKMNSR
                     ADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIES
                     IFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLL
                     CYDQTKRFSATEALQSDYFKEEPKPEPLVLDGLVSCHEYEVKLARKQKRPNILSTNTN
                     NKGNGNSNNNNNNNNDDDDK"
     gene            complement(184803..185012)
                     /gene="HSK3"
                     /locus_tag="YKL138C-A"
     mRNA            complement(184803..185012)
                     /gene="HSK3"
                     /locus_tag="YKL138C-A"
                     /product="Hsk3p"
     CDS             complement(184803..185012)
                     /gene="HSK3"
                     /locus_tag="YKL138C-A"
                     /experiment="EXISTENCE:direct assay:GO:0008017 microtubule
                     binding [PMID:15664196|PMID:16777964]"
                     /experiment="EXISTENCE:direct assay:GO:0008608 attachment
                     of spindle microtubules to kinetochore [PMID:17620411]"
                     /experiment="EXISTENCE:direct assay:GO:0031116 positive
                     regulation of microtubule polymerization [PMID:15664196]"
                     /experiment="EXISTENCE:direct assay:GO:0042729 DASH
                     complex [PMID:15640796|PMID:15664196]"
                     /experiment="EXISTENCE:direct assay:GO:0051010 microtubule
                     plus-end binding [PMID:17620411|PMID:20479465]"
                     /experiment="EXISTENCE:direct assay:GO:0051987 positive
                     regulation of attachment of spindle microtubules to
                     kinetochore [PMID:20479465|PMID:20479468]"
                     /note="Essential subunit of the Dam1 complex (aka DASH
                     complex); complex couples kinetochores to the force
                     produced by MT depolymerization thereby aiding in
                     chromosome segregation; is transferred to the kinetochore
                     prior to mitosis"
                     /codon_start=1
                     /product="Hsk3p"
                     /protein_id="DAA09024.1"
                     /db_xref="SGD:S000028421"
                     /translation="MNANKQRQYNQLAHELRELQTNLQETTKQLDIMSKQCNENLVGQ
                     LGKVHGSWLIGSYIYYMEQMLGKTQ"
     gene            complement(185286..185681)
                     /gene="MRPL31"
                     /locus_tag="YKL138C"
                     /gene_synonym="mL60"
     mRNA            complement(185286..185681)
                     /gene="MRPL31"
                     /locus_tag="YKL138C"
                     /gene_synonym="mL60"
                     /product="mitochondrial 54S ribosomal protein YmL31"
     CDS             complement(185286..185681)
                     /gene="MRPL31"
                     /locus_tag="YKL138C"
                     /gene_synonym="mL60"
                     /experiment="EXISTENCE:curator inference:GO:0032543
                     mitochondrial translation [PMID:12392552]"
                     /experiment="EXISTENCE:direct assay:GO:0003735 structural
                     constituent of ribosome [PMID:12392552]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005762
                     mitochondrial large ribosomal subunit [PMID:12392552]"
                     /note="Mitochondrial ribosomal protein of the large
                     subunit"
                     /codon_start=1
                     /product="mitochondrial 54S ribosomal protein YmL31"
                     /protein_id="DAA09025.1"
                     /db_xref="SGD:S000001621"
                     /translation="MFGPFKLTSPVAGGLLWKIPWRMSTHQKTRQRERLRNVDQVIKQ
                     LTLGLHVQRCQDKGLTYQEAMESKKKYKPRSKSLRLLNKPSVFPKENQMSSKDKYWTF
                     DKKAVGYRKGIHKVPKWTKISIRKAPKFF"
     gene            185957..186292
                     /gene="CMC1"
                     /locus_tag="YKL137W"
     mRNA            185957..186292
                     /gene="CMC1"
                     /locus_tag="YKL137W"
                     /product="Cmc1p"
     CDS             185957..186292
                     /gene="CMC1"
                     /locus_tag="YKL137W"
                     /experiment="EXISTENCE:direct assay:GO:0005507 copper ion
                     binding [PMID:18443040]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005758
                     mitochondrial intermembrane space [PMID:19703468]"
                     /experiment="EXISTENCE:direct assay:GO:0031314 extrinsic
                     component of mitochondrial inner membrane [PMID:18443040]"
                     /experiment="EXISTENCE:genetic interaction:GO:0033617
                     mitochondrial cytochrome c oxidase assembly
                     [PMID:23198688]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0033617
                     mitochondrial cytochrome c oxidase assembly
                     [PMID:18443040|PMID:23198688]"
                     /note="Copper-binding protein of the mitochondrial
                     intermembrane space; evolutionarily conserved; may be
                     involved in delivering copper from the matrix to the
                     cytochrome c oxidase complex; contains a twin CX9C motif"
                     /codon_start=1
                     /product="Cmc1p"
                     /protein_id="DAA09026.1"
                     /db_xref="SGD:S000001620"
                     /translation="MEQNKDPQMISKHSSRLPIWVLSPREEQQARKNLKTETYKKCAN
                     FVQAMADCAKANGMKVFPTCDKQRDEMKSCLLFYQTDEKYLDGERDKIVLEKINKLEK
                     LCQKQSSTK"
     gene            complement(186460..188640)
                     /gene="APL2"
                     /locus_tag="YKL135C"
     mRNA            complement(186460..188640)
                     /gene="APL2"
                     /locus_tag="YKL135C"
                     /product="Apl2p"
     CDS             complement(186460..188640)
                     /gene="APL2"
                     /locus_tag="YKL135C"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0030121 AP-1
                     adaptor complex [PMID:10564262]"
                     /experiment="EXISTENCE:direct assay:GO:0030276 clathrin
                     binding [PMID:10564262]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006896 Golgi
                     to vacuole transport [PMID:17003107]"
                     /note="Beta-adaptin subunit of the clathrin-associated
                     protein (AP-1) complex; binds clathrin; involved in
                     clathrin-dependent Golgi protein sorting; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Apl2p"
                     /protein_id="DAA09027.1"
                     /db_xref="SGD:S000001618"
                     /translation="MPPLDKRIKKFLKDSIRIAPKISGKGELSELRTGLVSQYPQTRK
                     DAIKKTIQQMTLGKDVSSLFPDVLKNIATIDVEQKKLVYLYVMNYAETHPELCILAVN
                     TFITDAQDPNPLIRCMAIRTMSMIRVDKILEYIETPLRRTLHDDNAYVRKTAVICVAK
                     LFQLNKDLCVELGVVEDLVNALDDSNPLVIANATAALIEIHNMDMDAVDLSSLIQSHV
                     SQFLLALNECTEWARIIILGTLSEYSAKDSLEAQDIIDRVTAHLQHVNPAVVLATIKV
                     IVRNLPQIEYSSNSLIMKRLSSAFVSLMSTPPEMQYVALKNIRIILEKYPELLTKELR
                     IFYVKFNDPLYVKLEKIDILVRLVDPSNLKQCTLLLTELKEYAMEYEPEFVSRAIQAL
                     SQLGIKYAQESFVSKVLDILLELLERQDTIKDDCCISLCDLLRHCPGNDKMAKQVCAV
                     FNTWSNPEVLLQSDIAKCNYVWLLGQHPNNFSDLESKINIFIENFVQEEALTQMSLLM
                     TIVRLHATLTGSMLQSVLELATQQTHELDVRDMAMMYWRCLSMPNNESLVNDLCQNKL
                     PMISNTLEKFSPEVLEKLLMELGTISSIYFKPDSNRRKGKKYVQNIVKGKHIEELESM
                     AKNEISSKANDDVLLDFDERDDVTNTNAGMLNTLTTLGDLDDLFDFGPSEDATQINTN
                     DTKAVQGLKELKLGGDSNGISSGGKNNPDVSGGNIVSQDLLDLF"
     gene            complement(189124..191442)
                     /gene="OCT1"
                     /locus_tag="YKL134C"
     mRNA            complement(189124..191442)
                     /gene="OCT1"
                     /locus_tag="YKL134C"
                     /product="metalloendopeptidase"
     CDS             complement(189124..191442)
                     /gene="OCT1"
                     /locus_tag="YKL134C"
                     /EC_number="3.4.24.59"
                     /experiment="EXISTENCE:direct assay:GO:0004222
                     metalloendopeptidase activity [PMID:8831696]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005759
                     mitochondrial matrix [PMID:8035833]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006879
                     cellular iron ion homeostasis [PMID:10332043]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004222
                     metalloendopeptidase activity [PMID:8831696]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006627 protein
                     processing involved in protein targeting to mitochondrion
                     [PMID:8035833]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006879
                     cellular iron ion homeostasis [PMID:10332043]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0050821 protein
                     stabilization [PMID:21525245]"
                     /note="Mitochondrial intermediate peptidase; cleaves
                     destabilizing N-terminal residues of a subset of proteins
                     upon import, after their cleavage by mitochondrial
                     processing peptidase (Mas1p-Mas2p); may contribute to
                     mitochondrial iron homeostasis"
                     /codon_start=1
                     /product="metalloendopeptidase"
                     /protein_id="DAA09028.2"
                     /db_xref="SGD:S000001617"
                     /translation="MLRTIILKAGSNASIPSPSRQNKLLRFFATAGAVSRTSPGSIKK
                     IFDDNSYWRNINGQDANNSKISQYLFKKNKTGLFKNPYLTSPDGLRKFSQVSLQQAQE
                     LLDKMRNDFSESGKLTYIMNLDRLSDTLCRVIDLCEFIRSTHPDDAFVRAAQDCHEQM
                     FEFMNVLNTDVSLCNILKSVLNNPEVSSKLSAEELKVGKILLDDFEKSGIYMNPDVRE
                     KFIQLSQEISLVGQEFINHTDYPGSNSVKIPCKDLDNSKVSTFLLKQLNKDVKGQNYK
                     VPTFGYAAYALLKSCENEMVRKKLWTALHSCSDKQVKRLSHLIKLRAILANLMHKTSY
                     AEYQLEGKMAKNPKDVQDFILTLMNNTIEKTANELKFIAELKAKDLKKPLTTNTDEIL
                     KLVRPWDRDYYTGKYFQLNPSNSPNAKEISYYFTLGNVIQGLSDLFQQIYGIRLEPAI
                     TDEGETWSPDVRRLNVISEEEGIIGIIYCDLFERNGKTSNPAHFTVCCSRQIYPSETD
                     FSTIQVGENPDGTYFQLPVISLVCNFSPILIASKKSLCFLQLSEVETLFHEMGHAMHS
                     MLGRTHMQNISGTRCATDFVELPSILMEHFAKDIRILTKIGKHYGTGETIQADMLQRF
                     MKSTNFLQNCETYSQAKMAMLDQSFHDEKIISDIDNFDVVENYQALERRLKVLVDDQS
                     NWCGRFGHLFGYGATYYSYLFDRTIASKIWYALFEDDPYSRKNGDKFKKHLLKWGGLK
                     DPWKCIADVLECPMLEKGGSDAMEFIAQSHKS"
     gene            complement(191679..193070)
                     /gene="RCI50"
                     /locus_tag="YKL133C"
     mRNA            complement(191679..193070)
                     /gene="RCI50"
                     /locus_tag="YKL133C"
                     /product="Rci50p"
     CDS             complement(191679..193070)
                     /gene="RCI50"
                     /locus_tag="YKL133C"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:26928762]"
                     /note="Mitochondrial hypothetical protein; not required
                     for growth of cells lacking the mitochondrial genome;
                     SWAT-GFP and mCherry fusion proteins localize to the
                     mitochondria; YKL133C has a paralog, MGR3, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="Rci50p"
                     /protein_id="DAA09029.2"
                     /db_xref="SGD:S000001616"
                     /translation="MWKYLHRSVKNEGTVERLTNLNLFTNHRFKFYSTLKEQSFWRIP
                     FKRRSKLQKWVLSTGIVSFIAFNIWWVYWPHHTFPKPVAKILRKGLHSEIKKEGANYQ
                     KSLEYYLEALEECKAENVDLLSDEYTGIEIKIGEMYEKLHMYNDATALYGDMLKKFYN
                     ELSKTTDKSTKRKFFLLKRDLQILVRFNEINKDSETNATLLIMHLLLAQREFLENSPE
                     FKNVLSKSELLNNQQLDWKNFKGLPFIGKSKPDYQMHLNSKRKQELKIKEPESEQCVF
                     MKELLTARDLYTRYCLNRSNLSGALNSKITTLEWMLLADSPLDDILLAQAELGSIFYL
                     NSEKFEGSLYAIDNEPYKKSEPLELIRSRLQENQNSCLQYSADCYKSIISFANENQYP
                     KVAMESEMDQRILKALSLAHYGIGVINLHKGRLRASKKELKKAIRISEMIRFNELIEE
                     AQRELKKVDGTPI"
     gene            complement(193574..194866)
                     /gene="RMA1"
                     /locus_tag="YKL132C"
     mRNA            complement(193574..194866)
                     /gene="RMA1"
                     /locus_tag="YKL132C"
                     /product="putative tetrahydrofolate synthase"
     CDS             complement(193574..194866)
                     /gene="RMA1"
                     /locus_tag="YKL132C"
                     /EC_number="6.3.2.17"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961]"
                     /note="Putative dihydrofolate synthetase; similar to E.
                     coli folylpolyglutamate synthetase/dihydrofolate
                     synthetase; the authentic, non-tagged protein is detected
                     in highly purified mitochondria in high-throughput
                     studies; RMA1 has a paralog, FOL3, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="putative tetrahydrofolate synthase"
                     /protein_id="DAA09030.1"
                     /db_xref="SGD:S000001615"
                     /translation="MDDISGRQTLPRINRLLEHVGNPQDSLSILHIAGTNGKETVSKF
                     LTSILQHPGQQRQRVLIGRYTTSSLLNAKEEDISINNEAISLIEYSRIEKELIEADSS
                     LKLQCNNLELLTSVALVYFAKKNCQWCIIETGLAGKQDPGSIIAGQSRVCCAITNVGI
                     SDEAFLCKFLSQITESSTNKAIFLLDGSNDEFVRNTITKRCHDVGCPLEITDPSLRDY
                     NVHTDTWGTLEVRLPYSEEEYQIFNLRVAIAVLDFLSKEKKVCISKDQLSQGLISVDW
                     PRSLHRLDYCYESTSGKKIALLLDNANNAKAARNLACHLRTTYGDTPLTFVIAITTGK
                     KVSPLLDPLIRPQDYVIVTRFGSVVGMPWIQSLEPVNLLAFIKNRYTRNVNMQPDLQS
                     VWTFLETSGLKTIVPVIVCGSLYICKELLRLHNCHLPV"
     gene            complement(195288..196028)
                     /gene="SHE2"
                     /locus_tag="YKL130C"
     mRNA            complement(195288..196028)
                     /gene="SHE2"
                     /locus_tag="YKL130C"
                     /product="She2p"
     CDS             complement(195288..196028)
                     /gene="SHE2"
                     /locus_tag="YKL130C"
                     /experiment="EXISTENCE:direct assay:GO:0003729 mRNA
                     binding [PMID:11101531]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:8625407]"
                     /experiment="EXISTENCE:direct assay:GO:0005789 endoplasmic
                     reticulum membrane [PMID:16890529|PMID:24056370]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005934 cellular
                     bud tip [PMID:11032818]"
                     /experiment="EXISTENCE:direct assay:GO:0008289 lipid
                     binding [PMID:24056370]"
                     /experiment="EXISTENCE:direct assay:GO:0008298
                     intracellular mRNA localization
                     [PMID:11032818|PMID:24056370]"
                     /experiment="EXISTENCE:direct assay:GO:1990825
                     sequence-specific mRNA binding [PMID:28092367]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007533 mating
                     type switching [PMID:8625407]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0008298
                     intracellular mRNA localization [PMID:28092367]"
                     /note="RNA-binding protein that binds specific mRNAs and
                     interacts with She3p; part of the mRNA localization
                     machinery that restricts accumulation of certain proteins
                     to the bud; binds to ER-derived membranes and targets
                     mRNAs to cortical ER"
                     /codon_start=1
                     /product="She2p"
                     /protein_id="DAA09031.1"
                     /db_xref="SGD:S000001613"
                     /translation="MSKDKDIKVTPGTCELVEQILALLSRYLSSYIHVLNKFISHLRR
                     VATLRFERTTLIKFVKKLRFYNDCVLSYNASEFINEGKNELDPEADSFDKVILPIASM
                     FVKCVETFDLLNYYLTQSLQKEILSKTLNEDLTLTAESILAIDDTYNHFVKFSQWMIE
                     SLRIGSNLLDLEVVQFAIKCADEDGTNIGETDNIFLQEILPVNSEEEFQTLSAAWHSI
                     LDGKLSALDEEFDVVATKWHDKFGKLKN"
     rep_origin      196042..196287
                     /note="ARS1126; Autonomously Replicating Sequence"
                     /db_xref="SGD:S000119036"
     gene            complement(196349..200167)
                     /gene="MYO3"
                     /locus_tag="YKL129C"
     mRNA            complement(196349..200167)
                     /gene="MYO3"
                     /locus_tag="YKL129C"
                     /product="myosin 3"
     CDS             complement(196349..200167)
                     /gene="MYO3"
                     /locus_tag="YKL129C"
                     /experiment="EXISTENCE:direct assay:GO:0071944 cell
                     periphery [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:2000601 positive
                     regulation of Arp2/3 complex-mediated actin nucleation
                     [PMID:11604421]"
                     /experiment="EXISTENCE:genetic interaction:GO:0051666
                     actin cortical patch localization [PMID:18177206]"
                     /note="One of two type I myosins; localizes to actin
                     cortical patches; deletion of MYO3 has little effect on
                     growth, but myo3 myo5 double deletion causes severe
                     defects in growth and actin cytoskeleton organization;
                     MYO3 has a paralog, MYO5, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="myosin 3"
                     /protein_id="DAA09032.2"
                     /db_xref="SGD:S000001612"
                     /translation="MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLL
                     SKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVP
                     PHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKI
                     KDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVV
                     GQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGT
                     LEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVD
                     ASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVN
                     VSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYE
                     REKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLF
                     NSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFP
                     DDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLH
                     QVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLIL
                     RDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAA
                     IKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKG
                     SYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKY
                     TQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIM
                     IKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNP
                     GGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYN
                     PKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSK
                     GVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGD
                     IVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSS
                     QIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDD
                     NDDGDDDDDW"
     gene            complement(200884..201771)
                     /gene="PMU1"
                     /locus_tag="YKL128C"
     mRNA            complement(200884..201771)
                     /gene="PMU1"
                     /locus_tag="YKL128C"
                     /product="putative phosphomutase"
     CDS             complement(200884..201771)
                     /gene="PMU1"
                     /locus_tag="YKL128C"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /note="Putative phosphomutase; contains a region
                     homologous to the active site of phosphomutases;
                     overexpression suppresses the histidine auxotrophy of an
                     ade3 ade16 ade17 triple mutant and the temperature
                     sensitivity of a tps2 mutant"
                     /codon_start=1
                     /product="putative phosphomutase"
                     /protein_id="DAA09033.1"
                     /db_xref="SGD:S000001611"
                     /translation="MSLRAVPGYFAAYPSEGFQGLDSTKYDHLELINHKNWKELYHAI
                     PRNTKNRHYKLLILARHGQGYHNAAILRYGMEKWDAYWSLLSGDEHGEWLDSKLTPLG
                     KDQVRRTGSNVLLPMAKQLGMLPHVFFSSPMRRCLETFIESWTPVLAETQELPAGTKI
                     STRIIEGLRETLGSHTCDKRVAHSMAVDEYQDFSTESGHTVHWQYVPDYPEDDELWLP
                     DHRETCAEMDKRTLNGLFELFNQLSSEEKFISLTCHSGVIQSVLRNLQHPPIYNLDTG
                     KVVAVVVEVPVNTADRGRL"
     repeat_region   complement(202644..202983)
                     /note="Ty3 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000007054"
     gene            202999..203071
                     /locus_tag="YNCK0007W"
     tRNA            202999..203071
                     /locus_tag="YNCK0007W"
                     /product="tRNA-Lys"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:8915539]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:8915539]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030533 triplet
                     codon-amino acid adaptor activity [PMID:17560369]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032543
                     mitochondrial translation [PMID:17560369]"
                     /note="Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE
                     analysis; a small portion is imported into mitochondria
                     via interaction with mt lysyl-tRNA synthetase Msk1p and is
                     necessary to decode AAG codons at high temperature, when
                     base modification of mt-encoded tRNA-Lys is reduced"
                     /db_xref="SGD:S000006626"
     gene            203541..205253
                     /gene="PGM1"
                     /locus_tag="YKL127W"
     mRNA            203541..205253
                     /gene="PGM1"
                     /locus_tag="YKL127W"
                     /product="phosphoglucomutase PGM1"
     CDS             203541..205253
                     /gene="PGM1"
                     /locus_tag="YKL127W"
                     /EC_number="5.4.2.2"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:8385141]"
                     /experiment="EXISTENCE:genetic interaction:GO:0004614
                     phosphoglucomutase activity [PMID:8119301]"
                     /experiment="EXISTENCE:genetic interaction:GO:0005978
                     glycogen biosynthetic process [PMID:9252577]"
                     /experiment="EXISTENCE:genetic interaction:GO:0005992
                     trehalose biosynthetic process [PMID:9252577]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006011
                     UDP-glucose metabolic process [PMID:9252577]"
                     /experiment="EXISTENCE:genetic interaction:GO:0019255
                     glucose 1-phosphate metabolic process [PMID:8119301]"
                     /experiment="EXISTENCE:genetic interaction:GO:0019388
                     galactose catabolic process [PMID:8119301]"
                     /experiment="EXISTENCE:genetic interaction:GO:0051156
                     glucose 6-phosphate metabolic process [PMID:8119301]"
                     /note="Phosphoglucomutase, minor isoform; catalyzes the
                     conversion from glucose-1-phosphate to
                     glucose-6-phosphate, which is a key step in hexose
                     metabolism; PGM1 has a paralog, PGM2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="phosphoglucomutase PGM1"
                     /protein_id="DAA09034.1"
                     /db_xref="SGD:S000001610"
                     /translation="MSLLIDSVPTVAYKDQKPGTSGLRKKTKVFMDEPHYTENFIQAT
                     MQSIPNGSEGTTLVVGGDGRFYNDVIMNKIAAVGAANGVRKLVIGQGGLLSTPAASHI
                     IRTYEEKCTGGGIILTASHNPGGPENDLGIKYNLPNGGPAPESVTNAIWEASKKLTHY
                     KIIKNFPKLNLNKLGKNQKYGPLLVDIIDPAKAYVQFLKEIFDFDLIKSFLAKQRKDK
                     GWKLLFDSLNGITGPYGKAIFVDEFGLPAEEVLQNWHPLPDFGGLHPDPNLTYARTLV
                     DRVDREKIAFGAASDGDGDRNMIYGYGPAFVSPGDSVAIIAEYAPEIPYFAKQGIYGL
                     ARSFPTSSAIDRVAAKKGLRCYEVPTGWKFFCALFDAKKLSICGEESFGTGSNHIREK
                     DGLWAIIAWLNILAIYHRRNPEKEASIKTIQDEFWNEYGRTFFTRYDYEHIECEQAEK
                     VVALLSEFVSRPNVCGSHFPADESLTVIDCGDFSYRDLDGSISENQGLFVKFSNGTKF
                     VLRLSGTGSSGATIRLYVEKYTDKKENYGQTADVFLKPVINSIVKFLRFKEILGTDEP
                     TVRT"
     gene            205707..207749
                     /gene="YPK1"
                     /locus_tag="YKL126W"
                     /gene_synonym="SLI2"
     mRNA            205707..207749
                     /gene="YPK1"
                     /locus_tag="YKL126W"
                     /gene_synonym="SLI2"
                     /product="serine/threonine protein kinase YPK1"
     CDS             205707..207749
                     /gene="YPK1"
                     /locus_tag="YKL126W"
                     /gene_synonym="SLI2"
                     /EC_number="2.7.11.1"
                     /experiment="EXISTENCE:direct assay:GO:0004674 protein
                     serine/threonine kinase activity
                     [PMID:19966303|PMID:22080611|PMID:29352143]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:10825204|PMID:12221112]"
                     /experiment="EXISTENCE:direct assay:GO:0005886 plasma
                     membrane [PMID:10825204]"
                     /experiment="EXISTENCE:direct assay:GO:0005935 cellular
                     bud neck [PMID:10825204]"
                     /experiment="EXISTENCE:direct assay:GO:0006468 protein
                     phosphorylation [PMID:19966303]"
                     /experiment="EXISTENCE:direct assay:GO:0018105
                     peptidyl-serine phosphorylation [PMID:29352143]"
                     /experiment="EXISTENCE:direct assay:GO:0046777 protein
                     autophosphorylation [PMID:19966303]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006650
                     glycerophospholipid metabolic process [PMID:25258318]"
                     /experiment="EXISTENCE:genetic interaction:GO:0018105
                     peptidyl-serine phosphorylation [PMID:26582391]"
                     /experiment="EXISTENCE:genetic interaction:GO:0060237
                     regulation of fungal-type cell wall organization
                     [PMID:12221112]"
                     /experiment="EXISTENCE:genetic interaction:GO:0070941
                     eisosome assembly [PMID:18296441]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000749
                     response to pheromone triggering conjugation with cellular
                     fusion [PMID:25378585]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004674 protein
                     serine/threonine kinase activity
                     [PMID:10825204|PMID:26274562]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006468 protein
                     phosphorylation [PMID:10825204|PMID:19966303]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006650
                     glycerophospholipid metabolic process [PMID:25258318]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0060237
                     regulation of fungal-type cell wall organization
                     [PMID:12221112]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0061093
                     negative regulation of phospholipid translocation
                     [PMID:19966303]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0071311
                     cellular response to acetate [PMID:27671892]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0090155
                     negative regulation of sphingolipid biosynthetic process
                     [PMID:22080611]"
                     /note="S/T protein kinase; phosphorylates, downregulates
                     flippase activator Fpk1p; inactivates Orm1p and Orm2p by
                     phosphorylation in response to compromised sphingolipid
                     synthesis; involved in the TORC-dependent phosphorylation
                     of ribosomal proteins Rps6a/b (S6); mutations affect
                     receptor-mediated endocytosis and sphingolipid-mediated
                     and cell integrity signaling pathways; human homolog SGK1
                     can complement a null mutant and the inviability of a ypk1
                     ypk2 double mutant"
                     /codon_start=1
                     /product="serine/threonine protein kinase YPK1"
                     /protein_id="DAA09035.1"
                     /db_xref="SGD:S000001609"
                     /translation="MYSWKSKFKFGKSKEEKEAKHSGFFHSSKKEEQQNNQATAGEHD
                     ASITRSSLDRKGTINPSNSSVVPVRVSYDASSSTSTVRDSNGGNSENTNSSQNLDETA
                     NIGSTGTPNDATSSSGMMTIKVYNGDDFILPFPITSSEQILNKLLASGVPPPHKEISK
                     EVDALIAQLSRVQIKNQGPADEDLISSESAAKFIPSTIMLPGSSTLNPLLYFTIEFDN
                     TVATIEAEYGTIAKPGFNKISTFDVTRKLPYLKIDVFARIPSILLPSKTWQQEMGLQD
                     EKLQTIFDKINSNQDIHLDSFHLPINLSFDSAASIRLYNHHWITLDNGLGKINISIDY
                     KPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHT
                     LAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFY
                     TAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGT
                     PEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPD
                     GFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVS
                     NSMDTSNFDEEFTREKPIDSVVDEYLSESVQKQFGGWTYVGNEQLGSSMVQGRSIR"
     gene            208247..210130
                     /gene="RRN3"
                     /locus_tag="YKL125W"
     mRNA            208247..210130
                     /gene="RRN3"
                     /locus_tag="YKL125W"
                     /product="rDNA-binding RNA polymerase I transcriptional
                     factor"
     CDS             208247..210130
                     /gene="RRN3"
                     /locus_tag="YKL125W"
                     /experiment="EXISTENCE:direct assay:GO:0000182 rDNA
                     binding [PMID:23393135]"
                     /experiment="EXISTENCE:direct assay:GO:0001042 RNA
                     polymerase I core binding [PMID:11032814]"
                     /experiment="EXISTENCE:direct assay:GO:0001179 RNA
                     polymerase I general transcription initiation factor
                     binding [PMID:11032814]"
                     /experiment="EXISTENCE:direct assay:GO:0001181 RNA
                     polymerase I general transcription initiation factor
                     activity [PMID:11032814]"
                     /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
                     [PMID:19416370]"
                     /experiment="EXISTENCE:genetic interaction:GO:0001181 RNA
                     polymerase I general transcription initiation factor
                     activity [PMID:11032814]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006361
                     transcription initiation from RNA polymerase I promoter
                     [PMID:8670901]"
                     /experiment="EXISTENCE:physical interaction:GO:0001042 RNA
                     polymerase I core binding [PMID:11032814]"
                     /experiment="EXISTENCE:physical interaction:GO:0001179 RNA
                     polymerase I general transcription initiation factor
                     binding [PMID:11032814]"
                     /experiment="EXISTENCE:physical interaction:GO:0001181 RNA
                     polymerase I general transcription initiation factor
                     activity [PMID:11032814]"
                     /note="Protein required for transcription of rDNA by RNA
                     polymerase I; transcription factor independent of DNA
                     template; involved in recruitment of RNA polymerase I to
                     rDNA; structure reveals unique HEAT repeat fold and a
                     surface serine patch; phosphorylation of serine patch
                     impairs cell growth and reduces RNA polymerase I binding
                     in vitro and RNA polymerase I recruitment to the rDNA gene
                     in vivo"
                     /codon_start=1
                     /product="rDNA-binding RNA polymerase I transcriptional
                     factor"
                     /protein_id="DAA09036.1"
                     /db_xref="SGD:S000001608"
                     /translation="MMAFENTSKRPPQDFVAPIDQKKRKVQFSDSTGLVTLQPEEIKD
                     EVFSAAMYSRFVKSALDDLDKNDSTQIGIIANQVALPSKNPERINDKNLNILLDILSS
                     NINRIESSRGTFLIQSIINFEKWWELPPHTLSKYIYFIKILCSSIPKWWQDVSMILVS
                     CFILPIKQTVCHHDMLKYFLRMIPSSMGFIDTYLAKFFPNKNDTRRKLVNYTSNLLKL
                     RGYCSELGFQIWSLLIEKIISIDVELQNELDELDDDVDDDDLEEVDLEDDDDLDDDSG
                     DDDDENCGNSNEELRSGAADGSQSDSEDMDIIEGMDGTEEYNVELTQGIKELSTKLDS
                     ILTLVSTHVEEQVTPESLESGEGVGVFNTLTTLFKTHVLPTYYTRSIQYIMFHVSQQQ
                     LELMDSFLVTLIDISFAVNEAAEKKIKSLQYLGSYIARAKKLSRTQIIFVASYLTSWL
                     NRYVIEREEEVDQRGGMERFKHFYAAFQALCYIFCFRHNIFRDTDGNWECELDKFFQR
                     MVISKFNPLKFCNENVMLMFARIAQQESVAYCFSIIENNNNERLRGIIGKADSDKKEN
                     SAQANTTSSSWSLATRQQFIDLQSYFPYDPLFLKNYKILMKEYYIEWSEASGEYESDG
                     SDD"
     gene            210593..212332
                     /gene="SSH4"
                     /locus_tag="YKL124W"
                     /gene_synonym="MLF4"
     mRNA            210593..212332
                     /gene="SSH4"
                     /locus_tag="YKL124W"
                     /gene_synonym="MLF4"
                     /product="Ssh4p"
     CDS             210593..212332
                     /gene="SSH4"
                     /locus_tag="YKL124W"
                     /gene_synonym="MLF4"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:17287526]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:genetic interaction:GO:0016192
                     vesicle-mediated transport [PMID:17287526]"
                     /experiment="EXISTENCE:genetic interaction:GO:0043328
                     protein transport to vacuole involved in
                     ubiquitin-dependent protein catabolic process via the
                     multivesicular body sorting pathway
                     [PMID:18367543|PMID:30361468]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1990756
                     ubiquitin ligase-substrate adaptor activity
                     [PMID:30361468]"
                     /note="Specificity factor required for Rsp5p-dependent
                     ubiquitination; also required for sorting of cargo
                     proteins at the multivesicular body; identified as a
                     high-copy suppressor of a SHR3 deletion, increasing
                     steady-state levels of amino acid permeases"
                     /codon_start=1
                     /product="Ssh4p"
                     /protein_id="DAA09037.1"
                     /db_xref="SGD:S000001607"
                     /translation="MYVTFNEALDSSFGNLESPNHDFKVGDPNMVPTPPMDSDSAAIS
                     LAFLISLSITFAILMLILVVIAAYVTFCGDDESEYDEENALGTRTSGTLHSLFGKKHS
                     GILLDSSFASPGGFDDEIVLQERELEELPKMSAYEVELYIRAKEFQMMSPPMVKDFGT
                     YLDSDDQQFIKDRGIQSYFLLPSINDNIDEYGNFLPSFIVQDKLDIQFSKFNKSSSTV
                     MNYPLPHNRKDAVYFEVKIFRHIQKSNSIFSIGLTTVPYPYFRVPGMAKYSIAYESTG
                     KLRINNPFTASTLLPKLEEGDTVGFGYRYKTGTIFITHNGKKLMDVTQNIGIDLFIGI
                     GAFNAAYTRTYTRDGLLEDPDNVSFREALSEGKDIEVAKDLQRVHDPHDESDEMTSDE
                     VELHVNLGQVGFVFIEANVKKYAFGSVYGQIGIPPAYNGTEIKKDTILQKGEELPPRY
                     ADTDNFFGSMKVKEGSSSRITAQTSKPLWSVGTYERISSNFDRENNVYHDSLETDDNN
                     TDNNVNNNDENAGCNENSPLLEDDGNKRPENSNTPREVSDGAINKNPRNKSTKKRQRN
                     RGKSSKKKNRSRK"
     gene            complement(212495..212998)
                     /gene="SRP21"
                     /locus_tag="YKL122C"
     mRNA            complement(212495..212998)
                     /gene="SRP21"
                     /locus_tag="YKL122C"
                     /product="signal recognition particle subunit SRP21"
     CDS             complement(212495..212998)
                     /gene="SRP21"
                     /locus_tag="YKL122C"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:11914276]"
                     /experiment="EXISTENCE:direct assay:GO:0005786 signal
                     recognition particle, endoplasmic reticulum targeting
                     [PMID:7925282]"
                     /experiment="EXISTENCE:direct assay:GO:0006614
                     SRP-dependent cotranslational protein targeting to
                     membrane [PMID:10921896]"
                     /note="Subunit of the signal recognition particle (SRP);
                     SRP functions in protein targeting to the endoplasmic
                     reticulum membrane; not found in mammalian SRP; forms a
                     pre-SRP structure in the nucleolus that is translocated to
                     the cytoplasm"
                     /codon_start=1
                     /product="signal recognition particle subunit SRP21"
                     /protein_id="DAA09038.1"
                     /db_xref="SGD:S000001605"
                     /translation="MSVKPIDNYITNSVRLFEVNPSQTLFSISYKPPTQKTDTKVSFR
                     THNSHLSLNYKFTTNKSKDVSRLLSALGPRGVSITPGKIEKIAQSKKKNNKIKESSKK
                     IKGKSIQDIVGLATLIVNTDVEKSDPAAKKTATEPKQKANAVQNNNGNSAASKKKKNK
                     NKGKKKR"
     rep_origin      213439..213743
                     /note="ARS1127; Autonomously Replicating Sequence"
                     /db_xref="SGD:S000119037"
     gene            214142..216700
                     /gene="DGR2"
                     /locus_tag="YKL121W"
     mRNA            214142..216700
                     /gene="DGR2"
                     /locus_tag="YKL121W"
                     /product="Dgr2p"
     CDS             214142..216700
                     /gene="DGR2"
                     /locus_tag="YKL121W"
                     /note="hypothetical protein; null mutant is resistant to
                     2-deoxy-D-glucose and displays abnormally elongated buds;
                     DGR2 has a paralog, YMR102C, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="Dgr2p"
                     /protein_id="DAA09039.1"
                     /db_xref="SGD:S000001604"
                     /translation="MFKSKTSTLSYDETPNSNEGDRNATPVNPKEKSQTKHLNIPGDR
                     SRHSSIADSKRSSSRYDGGYSADIIPAQLRFIDNIDYGTRLRKTLHRNSVVSNGYNKL
                     SENDRWYFDLFDRKYFENYLEEPTYIKIFKKKEGLEQFDRMFLAQELKIPDVYKSTTY
                     QGEPAVANSELFKNSICCCTFSHDGKYMVIGCKDGSLHLWKVINSPVKRSEMGRSEKS
                     VSASRANSLKIQRHLASISSHNGSISSNDLKPSDQFEGPSKQLHLYAPVFYSDVFRVF
                     MEHALDILDANWSKNGFLITASMDKTAKLWHPERKYSLKTFVHPDFVTSAIFFPNDDR
                     FIITGCLDHRCRLWSILDNEVSYAFDCKDLITSLTLSPPGGEYTIIGTFNGYIYVLLT
                     HGLKFVSSFHVSDKSTQGTTKNSFHPSSEYGKVQHGPRITGLQCFFSKVDKNLRLIVT
                     TNDSKIQIFDLNEKKPLELFKGFQSGSSRHRGQFLMMKNEPVVFTGSDDHWFYTWKMQ
                     SFNLSAEMNCTAPHRKKRLSGSMSLKGLLRIVSNKSTNDECLTETSNQSSSHTFTNSS
                     KNVLQTQTVGSQAIKNNHYISFHAHNSPVTCASIAPDVAIKNLSLSNDLIFELTSQYF
                     KEMGQNYSESKETCDNKPNHPVTETGGFSSNLSNVVNNVGTILITTDSQGLIRVFRTD
                     ILPEIRKKIIEKFHEYNLFHLEAAGKINNHNNDSILENRMDERSSTEDNEFSTTPPSN
                     THNSRPSHDFCELHPNNSPVISGMPSRASAIFKNSIFNKSNGSFISLKSRSESTSSTV
                     FGPHDIPRVSTTYPKLKCDVCNGSNFECASKNPIAGGDSGFTCADCGTILNNFR"
     gene            217344..218318
                     /gene="OAC1"
                     /locus_tag="YKL120W"
     mRNA            217344..218318
                     /gene="OAC1"
                     /locus_tag="YKL120W"
                     /product="Oac1p"
     CDS             217344..218318
                     /gene="OAC1"
                     /locus_tag="YKL120W"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005743
                     mitochondrial inner membrane [PMID:10428783]"
                     /experiment="EXISTENCE:direct assay:GO:0008272 sulfate
                     transport [PMID:10428783]"
                     /experiment="EXISTENCE:direct assay:GO:0015116 sulfate
                     transmembrane transporter activity [PMID:10428783]"
                     /experiment="EXISTENCE:direct assay:GO:0015131
                     oxaloacetate transmembrane transporter activity
                     [PMID:10428783]"
                     /experiment="EXISTENCE:direct assay:GO:0015729
                     oxaloacetate transport [PMID:10428783]"
                     /experiment="EXISTENCE:direct assay:GO:0034658
                     isopropylmalate transmembrane transporter activity
                     [PMID:18682385]"
                     /experiment="EXISTENCE:direct assay:GO:0034659
                     isopropylmalate transport [PMID:18682385]"
                     /experiment="EXISTENCE:direct assay:GO:1901239
                     malonate(1-) transmembrane transporter activity
                     [PMID:10428783]"
                     /note="Mitochondrial inner membrane transporter;
                     transports oxaloacetate, sulfate, thiosulfate, and
                     isopropylmalate; member of the mitochondrial carrier
                     family"
                     /codon_start=1
                     /product="Oac1p"
                     /protein_id="DAA09040.1"
                     /db_xref="SGD:S000001603"
                     /translation="MSSDNSKQDKQIEKTAAQKISKFGSFVAGGLAACIAVTVTNPIE
                     LIKIRMQLQGEMSASAAKVYKNPIQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSRL
                     GFYEPIRSSLNQLFFPDQEPHKVQSVGVNVFSGAASGIIGAVIGSPLFLVKTRLQSYS
                     EFIKIGEQTHYTGVWNGLVTIFKTEGVKGLFRGIDAAILRTGAGSSVQLPIYNTAKNI
                     LVKNDLMKDGPALHLTASTISGLGVAVVMNPWDVILTRIYNQKGDLYKGPIDCLVKTV
                     RIEGVTALYKGFAAQVFRIAPHTIMCLTFMEQTMKLVYSIESRVLGHN"
     gene            complement(218570..219217)
                     /gene="VPH2"
                     /locus_tag="YKL119C"
                     /gene_synonym="CLS10"
                     /gene_synonym="VMA12"
     mRNA            complement(218570..219217)
                     /gene="VPH2"
                     /locus_tag="YKL119C"
                     /gene_synonym="CLS10"
                     /gene_synonym="VMA12"
                     /product="Vph2p"
     CDS             complement(218570..219217)
                     /gene="VPH2"
                     /locus_tag="YKL119C"
                     /gene_synonym="CLS10"
                     /gene_synonym="VMA12"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005789 endoplasmic
                     reticulum membrane [PMID:9325326]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007035
                     vacuolar acidification [PMID:1628805]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0070072
                     vacuolar proton-transporting V-type ATPase complex
                     assembly [PMID:9325326]"
                     /experiment="EXISTENCE:physical interaction:GO:1990871
                     Vma12-Vma22 assembly complex [PMID:9660861]"
                     /note="Integral membrane protein required for V-ATPase
                     function; not an actual component of the vacuolar
                     H+-ATPase (V-ATPase) complex; functions in the assembly of
                     the V-ATPase; localized to the endoplasmic reticulum (ER);
                     involved in methionine restriction extension of
                     chronological lifespan in an autophagy-dependent manner"
                     /codon_start=1
                     /product="Vph2p"
                     /protein_id="DAA09041.1"
                     /db_xref="SGD:S000001602"
                     /translation="MFEIKLNDRITEFLRKFKNSAKSNEGIDEDIDLFLKRHAIPMQS
                     LLFYVKEYRKDSDLQCSIKELLKPLEFEFKPKAVRGLHYSEDFKKKLEFLKYQEQELE
                     YQSMVKRSKSVFSLQEDDELTPSQINKQIKEQVTTVFNVLVSVISVVVAIWYWTGSST
                     NFPVHVRLLLCLFFGILVLVADVVVYNSYLKKLEEAKVKEKTKVEKKKVLSKITL"
     repeat_region   complement(219395..219723)
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000007051"
     gene            219895..219967
                     /locus_tag="YNCK0008W"
     tRNA            219895..219967
                     /locus_tag="YNCK0008W"
                     /product="tRNA-Ala"
                     /experiment="EXISTENCE:curator inference:GO:0005829
                     cytosol [PMID:9023104]"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
                     analysis; one of 11 nuclear tRNA genes containing the
                     tDNA-anticodon AGC (converted to IGC in the mature tRNA),
                     decodes GCU and GCC codons into alanine, one of 16 nuclear
                     tRNAs for alanine"
                     /db_xref="SGD:S000006515"
     gene            220324..220974
                     /gene="SBA1"
                     /locus_tag="YKL117W"
                     /gene_synonym="CST18"
     mRNA            220324..220974
                     /gene="SBA1"
                     /locus_tag="YKL117W"
                     /gene_synonym="CST18"
                     /product="Hsp90 cochaperone SBA1"
     CDS             220324..220974
                     /gene="SBA1"
                     /locus_tag="YKL117W"
                     /gene_synonym="CST18"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:10207098]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:10207098]"
                     /experiment="EXISTENCE:direct assay:GO:0032212 positive
                     regulation of telomere maintenance via telomerase
                     [PMID:17389357]"
                     /experiment="EXISTENCE:direct assay:GO:0043392 negative
                     regulation of DNA binding [PMID:23022381]"
                     /experiment="EXISTENCE:direct assay:GO:0051972 regulation
                     of telomerase activity [PMID:17389357]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006457 protein
                     folding [PMID:9632755]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032212
                     positive regulation of telomere maintenance via telomerase
                     [PMID:17389357]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051087
                     chaperone binding [PMID:9632755]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051972
                     regulation of telomerase activity [PMID:17389357]"
                     /experiment="EXISTENCE:physical interaction:GO:0006457
                     protein folding [PMID:9632755]"
                     /experiment="EXISTENCE:physical interaction:GO:0051087
                     chaperone binding [PMID:9632755]"
                     /note="Co-chaperone that binds and regulates Hsp90 family
                     chaperones; plays a role in determining prion variants;
                     important for pp60v-src activity in yeast; homologous to
                     the mammalian p23 proteins, and like p23 can regulate
                     telomerase activity; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="Hsp90 cochaperone SBA1"
                     /protein_id="DAA09042.1"
                     /db_xref="SGD:S000001600"
                     /translation="MSDKVINPQVAWAQRSSTTDPERNYVLITVSIADCDAPELTIKP
                     SYIELKAQSKPHVGDENVHHYQLHIDLYKEIIPEKTMHKVANGQHYFLKLYKKDLESE
                     YWPRLTKEKVKYPYIKTDFDKWVDEDEQDEVEAEGNDAAQGMDFSQMMGGAGGAGGAG
                     GMDFSQMMGGAGGAGSPDMAQLQQLLAQSGGNLDMGDFKENDEEDEEEEIEPEVKA"
     gene            complement(221344..222900)
                     /gene="PRR1"
                     /locus_tag="YKL116C"
     mRNA            complement(221344..222900)
                     /gene="PRR1"
                     /locus_tag="YKL116C"
                     /product="serine/threonine protein kinase PRR1"
     CDS             complement(221344..222900)
                     /gene="PRR1"
                     /locus_tag="YKL116C"
                     /EC_number="2.7.11.1"
                     /experiment="EXISTENCE:direct assay:GO:0004672 protein
                     kinase activity [PMID:16319894]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0006468 protein
                     phosphorylation [PMID:16319894]"
                     /experiment="EXISTENCE:genetic interaction:GO:0031138
                     negative regulation of conjugation with cellular fusion
                     [PMID:11337509]"
                     /experiment="EXISTENCE:genetic interaction:GO:0046020
                     negative regulation of transcription from RNA polymerase
                     II promoter by pheromones [PMID:11337509]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031138
                     negative regulation of conjugation with cellular fusion
                     [PMID:11337509]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0046020
                     negative regulation of transcription from RNA polymerase
                     II promoter by pheromones [PMID:11337509]"
                     /note="Serine/threonine protein kinase; inhibits pheromone
                     induced signaling downstream of MAPK, possibly at the
                     level of the Ste12p transcription factor"
                     /codon_start=1
                     /product="serine/threonine protein kinase PRR1"
                     /protein_id="DAA09043.1"
                     /db_xref="SGD:S000001599"
                     /translation="MDEYSSIYSQPKTPRLKQEGFPDSIGDQHEKALIDENGEEDKKM
                     ASTEGTTGDSRSTPLTVSIPTFENVQALPTPMTYTPLSPGNLSMSPIDQSSLNIPKRR
                     SHARLLDDMLSVTQPNQRVVSELIAPANLSPQRVVSLPTVTEEALVNDSVDSDNYTKE
                     PYFPESSSSTEKCDDDIFQGFLLDHWDRPLLWKKVRPIGSGNFSTVLLYELMDQSNPK
                     LKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLG
                     INNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRI
                     FTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLC
                     KKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFDPPPN
                     ASARQRSRATSHRIARFDWRWYRLSDYKTNVGKQIVENTLTRKNQRWSINEIYESPFV
                     KTIADTLSFS"
     gene            complement(223352..224455)
                     /gene="APN1"
                     /locus_tag="YKL114C"
     mRNA            complement(223352..224455)
                     /gene="APN1"
                     /locus_tag="YKL114C"
                     /product="DNA-(apurinic or apyrimidinic site) lyase APN1"
     CDS             complement(223352..224455)
                     /gene="APN1"
                     /locus_tag="YKL114C"
                     /experiment="EXISTENCE:direct assay:GO:0003906
                     DNA-(apurinic or apyrimidinic site) endonuclease activity
                     [PMID:12767225]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:7690756]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:11238901]"
                     /experiment="EXISTENCE:direct assay:GO:0006284
                     base-excision repair [PMID:9295360]"
                     /experiment="EXISTENCE:direct assay:GO:0008081 phosphoric
                     diester hydrolase activity [PMID:3056935]"
                     /experiment="EXISTENCE:direct assay:GO:0008311
                     double-stranded DNA 3'-5' exodeoxyribonuclease activity
                     [PMID:16024777]"
                     /experiment="EXISTENCE:direct assay:GO:0017005
                     3'-tyrosyl-DNA phosphodiesterase activity [PMID:12397185]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0003906
                     DNA-(apurinic or apyrimidinic site) endonuclease activity
                     [PMID:1693433]"
                     /note="Major apurinic/apyrimidinic endonuclease; 3'-repair
                     diesterase; involved in repair of DNA damage by oxidation
                     and alkylating agents; also functions as a 3'-5'
                     exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine;
                     genetically interacts with NTG1 to maintain mitochondrial
                     genome integrity"
                     /codon_start=1
                     /product="DNA-(apurinic or apyrimidinic site) lyase APN1"
                     /protein_id="DAA09044.1"
                     /db_xref="SGD:S000001597"
                     /translation="MPSTPSFVRSAVSKYKFGAHMSGAGGISNSVTNAFNTGCNSFAM
                     FLKSPRKWVSPQYTQEEIDKFKKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSY
                     ESFMDDLNRCEQLGIGLYNLHPGSTLKGDHQLQLKQLASYLNKAIKETKFVKIVLENM
                     AGTGNLVGSSLVDLKEVIGMIEDKSRIGVCIDTCHTFAAGYDISTTETFNNFWKEFND
                     VIGFKYLSAVHLNDSKAPLGANRDLHERLGQGYLGIDVFRMIAHSEYLQGIPIVLETP
                     YENDEGYGNEIKLMEWLESKSESELLEDKEYKEKNDTLQKLGAKSRKEQLDKFEVKQK
                     KRAGGTKRKKATAEPSDNDILSQMTKKRKTKKE"
     gene            complement(224727..225875)
                     /gene="RAD27"
                     /locus_tag="YKL113C"
                     /gene_synonym="ERC11"
                     /gene_synonym="FEN1"
                     /gene_synonym="RTH1"
     mRNA            complement(224727..225875)
                     /gene="RAD27"
                     /locus_tag="YKL113C"
                     /gene_synonym="ERC11"
                     /gene_synonym="FEN1"
                     /gene_synonym="RTH1"
                     /product="multifunctional nuclease RAD27"
     CDS             complement(224727..225875)
                     /gene="RAD27"
                     /locus_tag="YKL113C"
                     /gene_synonym="ERC11"
                     /gene_synonym="FEN1"
                     /gene_synonym="RTH1"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:19699691|PMID:22932476|PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:19699691]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:22932476]"
                     /experiment="EXISTENCE:direct assay:GO:0006303
                     double-strand break repair via nonhomologous end joining
                     [PMID:15342630]"
                     /experiment="EXISTENCE:direct assay:GO:0008409 5'-3'
                     exonuclease activity [PMID:9166764]"
                     /experiment="EXISTENCE:direct assay:GO:0017108 5'-flap
                     endonuclease activity [PMID:11825897]"
                     /experiment="EXISTENCE:direct assay:GO:0043137 DNA
                     replication, removal of RNA primer [PMID:16837458]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006286
                     base-excision repair, base-free sugar-phosphate removal
                     [PMID:9927726]"
                     /experiment="EXISTENCE:genetic interaction:GO:0035753
                     maintenance of DNA trinucleotide repeats [PMID:16079237]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006286
                     base-excision repair, base-free sugar-phosphate removal
                     [PMID:9927726]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007534 gene
                     conversion at mating-type locus [PMID:10025407]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0035753
                     maintenance of DNA trinucleotide repeats [PMID:16079237]"
                     /note="5' to 3' exonuclease, 5' flap endonuclease;
                     required for Okazaki fragment processing and maturation,
                     for long-patch base-excision repair and large loop repair
                     (LLR), ribonucleotide excision repair; member of the S.
                     pombe RAD2/FEN1 family; relocalizes to the cytosol in
                     response to hypoxia"
                     /codon_start=1
                     /product="multifunctional nuclease RAD27"
                     /protein_id="DAA09045.1"
                     /db_xref="SGD:S000001596"
                     /translation="MGIKGLNAIISEHVPSAIRKSDIKSFFGRKVAIDASMSLYQFLI
                     AVRQQDGGQLTNEAGETTSHLMGMFYRTLRMIDNGIKPCYVFDGKPPDLKSHELTKRS
                     SRRVETEKKLAEATTELEKMKQERRLVKVSKEHNEEAQKLLGLMGIPYIIAPTEAEAQ
                     CAELAKKGKVYAAASEDMDTLCYRTPFLLRHLTFSEAKKEPIHEIDTELVLRGLDLTI
                     EQFVDLCIMLGCDYCESIRGVGPVTALKLIKTHGSIEKIVEFIESGESNNTKWKIPED
                     WPYKQARMLFLDPEVIDGNEINLKWSPPKEKELIEYLCDDKKFSEERVKSGISRLKKG
                     LKSGIQGRLDGFFQVVPKTKEQLAAAAKRAQENKKLNKNKNKVTKGRR"
     gene            226570..228765
                     /gene="ABF1"
                     /locus_tag="YKL112W"
                     /gene_synonym="BAF1"
                     /gene_synonym="EBF2"
                     /gene_synonym="OBF1"
                     /gene_synonym="REB2"
                     /gene_synonym="SBF1"
     mRNA            226570..228765
                     /gene="ABF1"
                     /locus_tag="YKL112W"
                     /gene_synonym="BAF1"
                     /gene_synonym="EBF2"
                     /gene_synonym="OBF1"
                     /gene_synonym="REB2"
                     /gene_synonym="SBF1"
                     /product="DNA-binding protein ABF1"
     CDS             226570..228765
                     /gene="ABF1"
                     /locus_tag="YKL112W"
                     /gene_synonym="BAF1"
                     /gene_synonym="EBF2"
                     /gene_synonym="OBF1"
                     /gene_synonym="REB2"
                     /gene_synonym="SBF1"
                     /experiment="EXISTENCE:direct assay:GO:0000113
                     nucleotide-excision repair factor 4 complex
                     [PMID:10601031]"
                     /experiment="EXISTENCE:direct assay:GO:0000978 RNA
                     polymerase II cis-regulatory region sequence-specific DNA
                     binding [PMID:7663308|PMID:27016735]"
                     /experiment="EXISTENCE:direct assay:GO:0001228 DNA-binding
                     transcription activator activity, RNA polymerase
                     II-specific [PMID:7663308]"
                     /experiment="EXISTENCE:direct assay:GO:0003688 DNA
                     replication origin binding [PMID:16824194|PMID:3281162]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:15522095]"
                     /experiment="EXISTENCE:direct assay:GO:0006261
                     DNA-dependent DNA replication [PMID:11756546]"
                     /experiment="EXISTENCE:direct assay:GO:0006338 chromatin
                     remodeling [PMID:10684934|PMID:11713306]"
                     /experiment="EXISTENCE:direct assay:GO:0043565
                     sequence-specific DNA binding
                     [PMID:3275867|PMID:7663308|PMID:19111667]"
                     /experiment="EXISTENCE:direct assay:GO:0044374
                     sequence-specific DNA binding, bending [PMID:8206955]"
                     /experiment="EXISTENCE:direct assay:GO:0070911 global
                     genome nucleotide-excision repair [PMID:15177043]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006338
                     chromatin remodeling [PMID:10684934|PMID:11713306]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000122
                     negative regulation of transcription by RNA polymerase II
                     [PMID:15192094]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005634 nucleus
                     [PMID:15522095]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030466 silent
                     mating-type cassette heterochromatin assembly
                     [PMID:16908533|PMID:8582634]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045944
                     positive regulation of transcription by RNA polymerase II
                     [PMID:15192094]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0070911 global
                     genome nucleotide-excision repair [PMID:10601031]"
                     /note="DNA binding protein with possible
                     chromatin-reorganizing activity; involved in
                     transcriptional activation, gene silencing, and DNA
                     replication and repair"
                     /codon_start=1
                     /product="DNA-binding protein ABF1"
                     /protein_id="DAA09046.1"
                     /db_xref="SGD:S000001595"
                     /translation="MDKLVVNYYEYKHPIINKDLAIGAHGGKKFPTLGAWYDVINEYE
                     FQTRCPIILKNSHRNKHFTFACHLKNCPFKVLLSYAGNAASSETSSPSANNNTNPPGT
                     PDHIHHHSNNMNNEDNDNNNGSNNKVSNDSKLDFVTDDLEYHLANTHPDDTNDKVESR
                     SNEVNGNNDDDADANNIFKQQGVTIKNDTEDDSINKASIDRGLDDESGPTHGNDSGNH
                     RHNEEDDVHTQMTKNYSDVVNDEDINVAIANAVANVDSQSNNKHDGKDDDATNNNDGQ
                     DNNTNNDHNNNSNINNNNVGSHGISSHSPSSIRDTSMNLDVFNSATDDIPGPFVVTKI
                     EPYHSHPLEDNLSLGKFILTKIPKILQNDLKFDQILESSYNNSNHTVSKFKVSHYVEE
                     SGLLDILMQRYGLTAEDFEKRLLSQIARRITTYKARFVLKKKKMGEYNDLQPSSSSNN
                     NNNNDGELSGTNLRSNSIDYAKHQEISSAGTSSNTTKNVNNNKNDSNDDNNGNNNNDA
                     SNLMESVLDKTSSHRYQPKKMPSVNKWSKPDQITHSDVSMVGLDESNDGGNENVHPTL
                     AEVDAQEARETAQLAIDKINSYKRSIDDKNGDGHNNSSRNVVDENLINDMDSEDAHKS
                     KRQHLSDITLEERNEDDKLPHEVAEQLRLLSSHLKEVENLHQNNDDDVDDVMVDVDVE
                     SQYNKNTTHHNNHHSQPHHDEEDVAGLIGKADDEEDLSDENIQPELRGQ"
     gene            complement(228939..229880)
                     /gene="KTI12"
                     /locus_tag="YKL110C"
                     /gene_synonym="TOT4"
     mRNA            complement(228939..229880)
                     /gene="KTI12"
                     /locus_tag="YKL110C"
                     /gene_synonym="TOT4"
                     /product="Kti12p"
     CDS             complement(228939..229880)
                     /gene="KTI12"
                     /locus_tag="YKL110C"
                     /gene_synonym="TOT4"
                     /experiment="EXISTENCE:direct assay:GO:0003682 chromatin
                     binding [PMID:15772087]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:12139626]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:12139626]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006357
                     regulation of transcription by RNA polymerase II
                     [PMID:15772087]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0002098 tRNA
                     wobble uridine modification [PMID:18755837]"
                     /note="Protein that plays a role in modification of tRNA
                     wobble nucleosides; protein plays role in tRNA wobble
                     nucleoside modification with Elongator complex; involved
                     in sensitivity to G1 arrest induced by zymocin; interacts
                     with chromatin throughout the genome; also interacts with
                     Cdc19p"
                     /codon_start=1
                     /product="Kti12p"
                     /protein_id="DAA09047.1"
                     /db_xref="SGD:S000001593"
                     /translation="MPLVLFTGYPCSGKTTLAKHLVQLLQSKIDATPSLSKYSITYHS
                     DESLGIKHSDYITSQDERKLRSEIISAVKRDLSKNKIVIVDSLNYIKGFRYQLHCEVK
                     NLSTTFCVIQTLCPPETIFEWNKTSNPNPWEPELLNQLIQRYEEPNSSNRWDSPLFAI
                     LTPQDNITDYIDDICKVVFQTSKSAKNSGHNDPLSKGLQKPNSATVLKPASQSNFIQV
                     LDIETSKIIKTIMNHIKSLTSIGGVSNGTRVIVSEGITDINDDGCFFVDLPIGNVVTL
                     AQLQRLKRQFINFNKLRDIDQDRIGPLFADYLNKNLN"
     gene            232227..233891
                     /gene="HAP4"
                     /locus_tag="YKL109W"
     mRNA            232227..233891
                     /gene="HAP4"
                     /locus_tag="YKL109W"
                     /product="transcription factor HAP4"
     CDS             232227..233891
                     /gene="HAP4"
                     /locus_tag="YKL109W"
                     /experiment="EXISTENCE:direct assay:GO:0016602
                     CCAAT-binding factor complex [PMID:2676721]"
                     /experiment="EXISTENCE:direct assay:GO:0061629 RNA
                     polymerase II-specific DNA-binding transcription factor
                     binding [PMID:11423663]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000436 carbon
                     catabolite activation of transcription from RNA polymerase
                     II promoter [PMID:2676721]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0003713
                     transcription coactivator activity [PMID:2123465]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0043457
                     regulation of cellular respiration [PMID:2676721]"
                     /experiment="EXISTENCE:physical interaction:GO:0061629 RNA
                     polymerase II-specific DNA-binding transcription factor
                     binding [PMID:11423663]"
                     /note="Transcription factor; subunit of the
                     heme-activated, glucose-repressed Hap2p/3p/4p/5p
                     CCAAT-binding complex, a transcriptional activator and
                     global regulator of respiratory gene expression; provides
                     the principal activation function of the complex; involved
                     in diauxic shift"
                     /codon_start=1
                     /product="transcription factor HAP4"
                     /protein_id="DAA09048.1"
                     /db_xref="SGD:S000001592"
                     /translation="MTAKTFLLQASASRPRSNHFKNEHNNIPLAPVPIAPNTNHHNNS
                     SLEFENDGSKKKKKSSLVVRTSKHWVLPPRPRPGRRSSSHNTLPANNTNNILNVGPNS
                     RNSSNNNNNNNIISNRKQASKEKRKIPRHIQTIDEKLINDSNYLAFLKFDDLENEKFH
                     SSASSISSPSYSSPSFSSYRNRKKSEFMDDESCTDVETIAAHNSLLTKNHHIDSSSNV
                     HAPPTKKSKLNDFDLLSLSSTSSSATPVPQLTKDLNMNLNFHKIPHKASFPDSPADFS
                     PADSVSLIRNHSLPTNLQVKDKIEDLNEIKFFNDFEKLEFFNKYAKVNTNNDVNENND
                     LWNSYLQSMDDTTGKNSGNYQQVDNDDNMSLLNLPILEETVSSGQDDKVEPDEEDIWN
                     YLPSSSSQQEDSSRALKKNTNSEKANIQAKNDETYLFLQDQDESADSHHHDELGSEIT
                     LADNKFSYLPPTLEELMEEQDCNNGRSFKNFMFSNDTGIDGSAGTDDDYTKVLKSKKI
                     STSKSNANLYDLNDNNNDATATNELDQSSFIDDLDEDVDFLKVQVF"
     gene            234426..235787
                     /gene="SLD2"
                     /locus_tag="YKL108W"
                     /gene_synonym="DRC1"
     mRNA            234426..235787
                     /gene="SLD2"
                     /locus_tag="YKL108W"
                     /gene_synonym="DRC1"
                     /product="Sld2p"
     CDS             234426..235787
                     /gene="SLD2"
                     /locus_tag="YKL108W"
                     /gene_synonym="DRC1"
                     /experiment="EXISTENCE:direct assay:GO:0003688 DNA
                     replication origin binding [PMID:21109535]"
                     /experiment="EXISTENCE:direct assay:GO:0003697
                     single-stranded DNA binding [PMID:21109535]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0031261 DNA
                     replication preinitiation complex [PMID:20231317]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006270 DNA
                     replication initiation [PMID:17167415|PMID:17167417]"
                     /experiment="EXISTENCE:genetic interaction:GO:0031261 DNA
                     replication preinitiation complex [PMID:20231317]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000727
                     double-strand break repair via break-induced replication
                     [PMID:20516198]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0003688 DNA
                     replication origin binding [PMID:21109535]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0003697
                     single-stranded DNA binding [PMID:21109535]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031333
                     negative regulation of protein-containing complex assembly
                     [PMID:24307213]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0033314 mitotic
                     DNA replication checkpoint signaling [PMID:10097122]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0071163 DNA
                     replication preinitiation complex assembly
                     [PMID:20231317]"
                     /note="Single-stranded DNA origin-binding and annealing
                     protein; required for initiation of DNA replication;
                     phosphorylated in S phase by cyclin-dependent kinases
                     (Cdks), promoting origin binding, DNA replication and
                     Dpb11p complex formation; component of the preloading
                     complex; binds the Mcm2-7p complex to prevent
                     inappropriate Mcm2-7p interaction with the GINS complex in
                     G1; required for S phase checkpoint; relative distribution
                     to the nucleus increases upon DNA replication stress"
                     /codon_start=1
                     /product="Sld2p"
                     /protein_id="DAA09049.1"
                     /db_xref="SGD:S000001591"
                     /translation="MYSFELDKLKIELKTWEHDFIDKNKREPTRDDIKSLRTVRQMYK
                     QYSTLKKKQSLQRQKVDTQESVELPAHKKDHDEVVEIGPTPQVYGKAISIFDMNLSPI
                     KPIYMTFTNNIDVNNDNSKTISNESSPRKTILLKSSPADRTLVAEPISSVKRQLNFQM
                     LNASSTRTPTSSPCKNRNGKLVEIKKCSPTINPPLESGKPSGYYGPNSPLKLDEENIH
                     LNISLNSSTKRRLQIAYPSLQKTPSKDQADISTSFSPSPLIRRPLTKSLIELAREHTE
                     IVKEFGVLQEEDIEEEEEGEEGENGYDEKNHEDDFGLEDELIRPKVVKDIFQEDDDND
                     DSQAREDTFIRKRPKRRKVIRRLRDNDPETETAGFERDVHKELVKLKRRKVAEFLGST
                     SQISDTEFEHDPEASSGVVSSEQKPTAKRKGRKKYNLVSNNFRRLKLPKKNRFSNGRW
                     GRR"
     gene            236141..237070
                     /locus_tag="YKL107W"
     mRNA            236141..237070
                     /locus_tag="YKL107W"
                     /product="putative short-chain dehydrogenase/reductase"
     CDS             236141..237070
                     /locus_tag="YKL107W"
                     /experiment="EXISTENCE:direct assay:GO:0004029 aldehyde
                     dehydrogenase (NAD+) activity [PMID:31115629]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:31115629]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1901426
                     response to furfural [PMID:31115629]"
                     /note="NADH-dependent aldehyde reductase; involved in the
                     detoxification of acetaldehyde, glycolaldehyde, furfural,
                     formaldehyde and propionaldehyde; localizes to the
                     endoplasmic reticulum; member of the classical short-chain
                     dehydrogenase/reductase (SDR) family"
                     /codon_start=1
                     /product="putative short-chain dehydrogenase/reductase"
                     /protein_id="DAA09050.1"
                     /db_xref="SGD:S000001590"
                     /translation="MFWKKDPTVSWERKNINDIDFSRFNVAIIGGTGGLGRAISRELA
                     QRNARVTVVGQTFRDEDLKDKINFVKADLSLVSECKRISHSDEIPYEELTHLIFTTGI
                     FASRQRQATSEGLEKDMAVSYLSRYIIFHDVAKRLGISRTKKDDLPKVFIAGFPGNGQ
                     VGDPDDLNSDEKKYSAYATHMNTVAANESLVIDAKDRYTNIDTFGLNPGLIKTNIRNN
                     LLGSDTYLSRITEWIISWTCQSAETYAKTICTLIASPAIESRSGTMFSNKGDAILPSP
                     GLTKDVVEKFMENSELLVEKALRNQSPFTSSNE"
     gene            complement(237147..237266)
                     /locus_tag="YKL106C-A"
     mRNA            complement(237147..237266)
                     /locus_tag="YKL106C-A"
                     /product="hypothetical protein"
     CDS             complement(237147..237266)
                     /locus_tag="YKL106C-A"
                     /note="hypothetical protein; identified by homology to
                     uncharacterized proteins in other fungi"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA09051.1"
                     /db_xref="SGD:S000007616"
                     /translation="MPFPSILHLTIGRYASYDSNNHMRRRAKLMEAIFRIRTI"
     gene            237536..238891
                     /gene="AAT1"
                     /locus_tag="YKL106W"
     mRNA            237536..238891
                     /gene="AAT1"
                     /locus_tag="YKL106W"
                     /product="aspartate transaminase AAT1"
     CDS             237536..238891
                     /gene="AAT1"
                     /locus_tag="YKL106W"
                     /EC_number="2.6.1.1"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion
                     [PMID:22010850|PMID:14576278|PMID:16823961|PMID:24769239]"
                     /note="Mitochondrial aspartate aminotransferase; catalyzes
                     the conversion of oxaloacetate to aspartate in aspartate
                     and asparagine biosynthesis"
                     /codon_start=1
                     /product="aspartate transaminase AAT1"
                     /protein_id="DAA09052.1"
                     /db_xref="SGD:S000001589"
                     /translation="MLRTRLTNCSLWRPYYTSSLSRVPRAPPDKVLGLSEHFKKVKNV
                     NKIDLTVGIYKDGWGKVTTFPSVAKAQKLIESHLELNKNLSYLPITGSKEFQENVMKF
                     LFKESCPQFGPFYLAHDRISFVQTLSGTGALAVAAKFLALFISRDIWIPDPSWANHKN
                     IFQNNGFENIYRYSYYKDGQIDIDGWIEQLKTFAYNNQQENNKNPPCIILHACCHNPT
                     GLDPTKEQWEKIIDTIYELKMVPIVDMAYQGLESGNLLKDAYLLRLCLNVNKYPNWSN
                     GIFLCQSFAKNMGLYGERVGSLSVITPATANNGKFNPLQQKNSLQQNIDSQLKKIVRG
                     MYSSPPGYGSRVVNVVLSDFKLKQQWFKDVDFMVQRLHHVRQEMFDRLGWPDLVNFAQ
                     QHGMFYYTRFSPKQVEILRNNYFVYLTGDGRLSLSGVNDSNVDYLCESLEAVSKMDKL
                     A"
     gene            complement(239185..242583)
                     /gene="SEG2"
                     /locus_tag="YKL105C"
     mRNA            complement(239185..242583)
                     /gene="SEG2"
                     /locus_tag="YKL105C"
                     /product="Seg2p"
     CDS             complement(239185..242583)
                     /gene="SEG2"
                     /locus_tag="YKL105C"
                     /experiment="EXISTENCE:direct assay:GO:0071944 cell
                     periphery [PMID:26928762]"
                     /note="Eisosome component; likely plays only a minor role
                     in eisosome assembly; shown to interact with Seg1p by
                     affinity purification and mass spec; SWAT-GFP and mCherry
                     fusion proteins localize to the cell periphery; similar to
                     A. gossypii SEG gene which is important for stabilizing
                     eisosomes; SEG2 has a paralog, SEG1, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Seg2p"
                     /protein_id="DAA09053.1"
                     /db_xref="SGD:S000001588"
                     /translation="MIQESSPDALAAAAAIGNALSYNGRTVDKSKIPQYNQSFTSRTT
                     SIAGINRYTMLSNSRTNSRMLLMNGNVRQYSKRTSSLPNQGHKNTSNNSAGRRQHRAH
                     EDAETTFREFGGKQSSKVLNISSSTGQNSKSRTTSLGNSGSTIRTIKKYIPGPRGLMA
                     VEVPVEVEPPRYSLSNRSNQRGGRAYSLPTRNNKTSLMHRNKTTKKAGSQEKKSESGG
                     KSKNDYHGKVLSKMHTTSLKQRHNNVPLIPTTMNEETEQELQEDLHDPLEFKPMIISD
                     DENSFIEPSVLDRSIPKKDKSGLSGREKKEEIETLLKEVHSLEEKISNIEIAKLNEEE
                     REQSLILELRKVKLDEERRMELLKRELNIVKENADLEAQELKLIESKRKQHFHKGQEV
                     ASEVKSITIRQPTLSEPKPAYVPPEDVEKEPSTLSNQTQNIENAENIDSVDAEGNLVD
                     PILLGSLNNSNFHMNSDNEVRCIADSNSLTGSELSDYNYIEGSATDLRATAKTSVESE
                     IGGNQVGLKIPQDDDSEKQEERTKGKKSGLVDTNCFLVQKEDQEEALSDNEPESSEKF
                     PSTSGIENVKLEDETGSVMDKNNGPNNDKDDDDDKDNDNDDDDDKDDDVNDDDKDENV
                     DDDENVDDDDDDDDDDDDEYHDSYDVIMRDPVQIEQDISDVPSLKHPSEYSTETEDNK
                     KKEQNSENAEVSQSGTNMAKYLRGANPYLTNTSSDTFSLDSENVNSKSSTDTTRVAPD
                     LLKSSLQPQLRSDLKQSAVPSSTSSSIYSIETSPNIDSSTGKTASNTKTNSHGPPTSI
                     SKQKYDQSSSHQIPVMSPKRLDDKRKITNRSCLRTLRGSSNEATLSHNIVYPASDSSS
                     SPPYHSKKPSNPPSSGNLASHEASKCFPKAPQASTTSRRLPDHVPLYIDKNNSALYPK
                     EPPARKSSFEKERPAKDNLGFRSMSLREPLITKNATATAAENLDVEEKKEKGGHVSRK
                     SWTFGLPSPLKRRTSHSTHTTNETEIVNPMTNFKNKTNENDMPILANKKSCNNDDSSP
                     YTASSMNTNDVSEAGTEGHRFSLFGNKSQLSNRNISGGTATLESSNPDLPTALPLSVP
                     VTIIDKNGEIHKLHNDDAAIKDKSHDRHGHSKFGRKLKKIFGRK"
     gene            complement(243220..245373)
                     /gene="GFA1"
                     /locus_tag="YKL104C"
     mRNA            complement(243220..245373)
                     /gene="GFA1"
                     /locus_tag="YKL104C"
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing) GFA1"
     CDS             complement(243220..245373)
                     /gene="GFA1"
                     /locus_tag="YKL104C"
                     /EC_number="2.6.1.16"
                     /experiment="EXISTENCE:direct assay:GO:0004360
                     glutamine-fructose-6-phosphate transaminase (isomerizing)
                     activity [PMID:2656689]"
                     /experiment="EXISTENCE:genetic interaction:GO:0034221
                     fungal-type cell wall chitin biosynthetic process
                     [PMID:11895440]"
                     /note="Glutamine-fructose-6-phosphate amidotransferase;
                     catalyzes the formation of glucosamine-6-P and glutamate
                     from fructose-6-P and glutamine in the first step of
                     chitin biosynthesis; GFA1 has a paralogous region,
                     comprising ORFs YMR084W-YMR085W, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing) GFA1"
                     /protein_id="DAA09054.1"
                     /db_xref="SGD:S000001587"
                     /translation="MCGIFGYCNYLVERSRGEIIDTLVDGLQRLEYRGYDSTGIAIDG
                     DEADSTFIYKQIGKVSALKEEITKQNPNRDVTFVSHCGIAHTRWATHGRPEQVNCHPQ
                     RSDPEDQFVVVHNGIITNFRELKTLLINKGYKFESDTDTECIAKLYLHLYNTNLQNGH
                     DLDFHELTKLVLLELEGSYGLLCKSCHYPNEVIATRKGSPLLIGVKSEKKLKVDFVDV
                     EFPEENAGQPEIPLKSNNKSFGLGPKKAREFEAGSQNANLLPIAANEFNLRHSQSRAF
                     LSEDGSPTPVEFFVSSDAASVVKHTKKVLFLEDDDLAHIYDGELHIHRSRREVGASMT
                     RSIQTLEMELAQIMKGPYDHFMQKEIYEQPESTFNTMRGRIDYENNKVILGGLKAWLP
                     VVRRARRLIMIACGTSYHSCLATRAIFEELSDIPVSVELASDFLDRKCPVFRDDVCVF
                     VSQSGETADTMLALNYCLERGALTVGIVNSVGSSISRVTHCGVHINAGPEIGVASTKA
                     YTSQYIALVMFALSLSDDRVSKIDRRIEIIQGLKLIPGQIKQVLKLEPRIKKLCATEL
                     KDQKSLLLLGRGYQFAAALEGALKIKEISYMHSEGVLAGELKHGVLALVDENLPIIAF
                     GTRDSLFPKVVSSIEQVTARKGHPIIICNENDEVWAQKSKSIDLQTLEVPQTVDCLQG
                     LINIIPLQLMSYWLAVNKGIDVDFPRNLAKSVTVE"
     gene            245032..245286
                     /locus_tag="YKL104W-A"
     mRNA            245032..245286
                     /locus_tag="YKL104W-A"
                     /product="hypothetical protein"
     CDS             245032..245286
                     /locus_tag="YKL104W-A"
                     /note="Novel ORF identified by enrichment-based
                     proteomics"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAD54808.1"
                     /db_xref="SGD:S000303811"
                     /translation="MNDHKLVFWVRSLRVTVNLFWSTVSSPSSMRNTTMRDKSNVSVR
                     ILLSNLLFQSTHFTDLLIDESRISFVTIDSNTGGIIASIF"
     gene            complement(246138..247682)
                     /gene="APE1"
                     /locus_tag="YKL103C"
                     /gene_synonym="API"
                     /gene_synonym="LAP4"
                     /gene_synonym="YSC1"
     mRNA            complement(246138..247682)
                     /gene="APE1"
                     /locus_tag="YKL103C"
                     /gene_synonym="API"
                     /gene_synonym="LAP4"
                     /gene_synonym="YSC1"
                     /product="metalloaminopeptidase APE1"
     CDS             complement(246138..247682)
                     /gene="APE1"
                     /locus_tag="YKL103C"
                     /gene_synonym="API"
                     /gene_synonym="LAP4"
                     /gene_synonym="YSC1"
                     /EC_number="3.4.11.22"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:1400574]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0034270 Cvt complex
                     [PMID:9151668|PMID:9412464|PMID:20659891]"
                     /experiment="EXISTENCE:direct assay:GO:0070006
                     metalloaminopeptidase activity [PMID:3882418]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032258
                     cytoplasm to vacuole transport by the Cvt pathway
                     [PMID:18725539]"
                     /note="Vacuolar aminopeptidase yscI; zinc
                     metalloproteinase that belongs to the peptidase family
                     M18; often used as a marker protein in studies of
                     autophagy and cytosol to vacuole targeting (CVT) pathway;
                     protein increases in abundance and relative distribution
                     to cytoplasmic foci increases upon DNA replication stress"
                     /codon_start=1
                     /product="metalloaminopeptidase APE1"
                     /protein_id="DAA09055.1"
                     /db_xref="SGD:S000001586"
                     /translation="MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCI
                     LEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKF
                     YTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPY
                     GGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGP
                     FDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQ
                     MDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVT
                     LYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNP
                     NFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNS
                     RSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVY
                     DEFGEL"
     gene            complement(248062..248367)
                     /locus_tag="YKL102C"
     mRNA            complement(248062..248367)
                     /locus_tag="YKL102C"
                     /product="hypothetical protein"
     CDS             complement(248062..248367)
                     /locus_tag="YKL102C"
                     /note="hypothetical protein; conserved across S.
                     cerevisiae strains; deletion confers sensitivity to citric
                     acid; predicted protein would include a thiol-disulfide
                     oxidoreductase active site"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA80309.1"
                     /db_xref="SGD:S000001585"
                     /translation="MCALFAEVSSTAAASCSFGVLLCSGSNCGRLVGSERRKVLYVFN
                     VNVCKKMSSYYFLRHDNIVIPYLLRLLVSDKEASNKNPLLPFLMDKERSHHFVRNMN"
     gene            248920..253476
                     /gene="HSL1"
                     /locus_tag="YKL101W"
                     /gene_synonym="ELM2"
                     /gene_synonym="NIK1"
     mRNA            248920..253476
                     /gene="HSL1"
                     /locus_tag="YKL101W"
                     /gene_synonym="ELM2"
                     /gene_synonym="NIK1"
                     /product="protein kinase HSL1"
     CDS             248920..253476
                     /gene="HSL1"
                     /locus_tag="YKL101W"
                     /gene_synonym="ELM2"
                     /gene_synonym="NIK1"
                     /EC_number="2.7.11.1"
                     /experiment="EXISTENCE:direct assay:GO:0000144 cellular
                     bud neck septin ring [PMID:27053666|PMID:9925642]"
                     /experiment="EXISTENCE:direct assay:GO:0004672 protein
                     kinase activity [PMID:9925642|PMID:16319894]"
                     /experiment="EXISTENCE:direct assay:GO:0004674 protein
                     serine/threonine kinase activity [PMID:11408575]"
                     /experiment="EXISTENCE:direct assay:GO:0005935 cellular
                     bud neck [PMID:10805747|PMID:15282802]"
                     /experiment="EXISTENCE:direct assay:GO:0006468 protein
                     phosphorylation [PMID:9925642|PMID:16319894]"
                     /experiment="EXISTENCE:direct assay:GO:0018105
                     peptidyl-serine phosphorylation [PMID:11408575]"
                     /experiment="EXISTENCE:direct assay:GO:0046777 protein
                     autophosphorylation [PMID:11408575|PMID:16861226]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000086 G2/M
                     transition of mitotic cell cycle [PMID:10490630]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004674 protein
                     serine/threonine kinase activity [PMID:11408575]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006468 protein
                     phosphorylation [PMID:10490630|PMID:10490648]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0018105
                     peptidyl-serine phosphorylation [PMID:11408575]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0044257
                     cellular protein catabolic process [PMID:23042131]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0044879 mitotic
                     morphogenesis checkpoint signaling [PMID:9925642]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0046777 protein
                     autophosphorylation [PMID:16861226]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051726
                     regulation of cell cycle [PMID:8647431]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1902935 protein
                     localization to septin ring [PMID:27053666]"
                     /experiment="EXISTENCE:physical interaction:GO:0000144
                     cellular bud neck septin ring [PMID:9925642]"
                     /note="Nim1p-related protein kinase; septin-binding kinase
                     that localizes to the bud neck septin ring and regulates
                     the morphogenesis checkpoint; phosphorylates Hsl7p and
                     cooperates with Elm1p to recruit Hsl7p to the mother-bud
                     neck, as a prerequisite for the subsequent recruitment,
                     phosphorylation, and degradation of Swe1p;
                     autophosphorylation enhances interactions with Hsl7p"
                     /codon_start=1
                     /product="protein kinase HSL1"
                     /protein_id="DAA09056.2"
                     /db_xref="SGD:S000001584"
                     /translation="MTGHVSKTSHVPKGRPSSLAKKAAKRAMAKVNSNPKRASGHLER
                     VVQSVNDATKRLSQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNME
                     TGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYG
                     IEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIH
                     YFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCG
                     SPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQM
                     PSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARG
                     KSNSDLHLLNNVSPSIVTLHSKGEIDESILRSLQILWHGVSRELITAKLLQKPMSEEK
                     LFYSLLLQYKQRHSISLSSSSENKKSATESSVNEPRIEYASKTANNTGLRSENNDVKT
                     LHSLEIHSEDTSTVNQNNAITGVNTEINAPVLAQKSQFSINTLSQPESDKAEAEAVTL
                     PPAIPIFNASSSRIFRNSYTSISSRSRRSLRLSNSRLSLSASTSRETVHDNEMPLPQL
                     PKSPSRYSLSRRAIHASPSTKSIHKSLSRKNIAATVAARRTLQNSASKRSLYSLQSIS
                     KRSLNLNDLLVFDDPLPSKKPASENVNKSEPHSLESDSDFEILCDQILFGNALDRILE
                     EEEDNEKERDTQRQRQNDTKSSADTFTISGVSTNKENEGPEYPTKIEKNQFNMSYKPS
                     ENMSGLSSFPIFEKENTLSSSYLEEQKPKRAALSDITNSFNKMNKQEGMRIEKKIQRE
                     QLQKKNDRPSPLKPIQHQELRVNSLPNDQGKPSLSLDPRRNISQPVNSKVESLLQGLK
                     FKKEPASHWTHERGSLFMSEHVEDEKPVKASDVSIESSYVPLTTVATSSRDPSVLAES
                     STIQKPMLSLPSSFLNTSMTFKNLSQILADDGDDKHLSVPQNQSRSVAMSHPLRKQSA
                     KISLTPRSNLNANLSVKRNQGSPGSYLSNDLDGISDMTFAMEIPTNTFTAQAIQLMNN
                     DTDNNKINTSPKASSFTKEKVIKSAAYISKEKEPDNSDTNYIPDYTIPNTYDEKAINI
                     FEDAPSDEGSLNTSSSESDSRASVHRKAVSIDTMATTNVLTPATNVRVSLYWNNNSSG
                     IPRETTEEILSKLRLSPENPSNTHMQKRFSSTRGSRDSNALGISQSLQSMFKDLEEDQ
                     DGHTSQADILESSMSYSKRRPSEESVNPKQRVTMLFDEEEEESKKVGGGKIKEEHTKL
                     DNKISEESSQLVLPVVEKKENANNTENNYSKIPKPSTIKVTKDTAMESNTQTHTKKPI
                     LKSVQNVEVEEAPSSDKKNWFVKLFQNFSSHNNATKASKNHVTNISFDDAHMLTLNEF
                     NKNSIDYQLKNLDHKFGRKVVEYDCKFVKGNFKFKIKITSTPNASTVITVKKRSKHSN
                     TSSNKAFEKFNDDVERVIRNAGRS"
     gene            complement(253697..255460)
                     /gene="YPF1"
                     /locus_tag="YKL100C"
     mRNA            complement(253697..255460)
                     /gene="YPF1"
                     /locus_tag="YKL100C"
                     /product="aspartic endopeptidase"
     CDS             complement(253697..255460)
                     /gene="YPF1"
                     /locus_tag="YKL100C"
                     /experiment="EXISTENCE:direct assay:GO:1990578 perinuclear
                     endoplasmic reticulum membrane [PMID:25454947]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0009267
                     cellular response to starvation [PMID:25454947]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042500
                     aspartic endopeptidase activity, intramembrane cleaving
                     [PMID:25454947]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051603
                     proteolysis involved in cellular protein catabolic process
                     [PMID:25454947]"
                     /note="Intramembrane aspartyl protease of the perinuclear
                     ER membrane; acts in a branch of ER-associated degradation
                     (ERAD) that degrades functional proteins rather than
                     misfolded proteins; regulates abundance of high-affinity
                     plasma membrane transporters, such as Ctr1p and Zrt1p,
                     during the starvation response; has a presenilin fold;
                     member of the GxGD family of intramembrane proteases;
                     closest human homolog is signal peptide peptidase (SPP)"
                     /codon_start=1
                     /product="aspartic endopeptidase"
                     /protein_id="DAA09057.1"
                     /db_xref="SGD:S000001583"
                     /translation="MDKYLNSFVDHLSEWSSRAFRNNSSSANQSASNKELEQVFEQIN
                     AIVENHNNKLTTAFDKISYRVAHKITHLVESHSLVFNYATLVLIASALVVIGSFTSIS
                     SIPFTALPPTREHSLFDPTDFDVDHDCHVIYRENDEDKKKKKKSKRFFDMMDEKHAII
                     LPLTSGCTLLALYFVIKKLHLNWLKYVVKILNFNITLLNIPAGTFVYSYFLNSLFRNL
                     SHLASWNPLVVLPRYRVTIADDNEDLNKIGGFVTNLNYKDGLTNSVVHKKTLDEIEKD
                     HWMKHFYRRELVEPKDIKSKRQISNMYLNSALIVSFVLSIVSTVYFYLSPNDWLISNA
                     VSMNMAIWSIAQLKLKNLKSGALILIALFFYDICFVFGTDVMVTVATNLDIPVKLSLP
                     VKFNTAQNNFNFSILGLGDIALPGMFIAMCYKYDIWKWHLDHDDTEFHFLNWSYVGKY
                     FITAMVSYVASLVSAMVSLSIFNTAQPALLYIVPSLLISTILVACWNKDFKQFWNFQY
                     DTIEVDKSLKKAIEKKENSITYSTFILSEYYNDADKYALLGDDVNENFDDDEEFVQEE
                     DLSDSSEEELSEEDLLDDESS"
     gene            complement(255720..256472)
                     /gene="UTP11"
                     /locus_tag="YKL099C"
     mRNA            complement(255720..256472)
                     /gene="UTP11"
                     /locus_tag="YKL099C"
                     /product="rRNA-processing protein UTP11"
     CDS             complement(255720..256472)
                     /gene="UTP11"
                     /locus_tag="YKL099C"
                     /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
                     [PMID:12068309]"
                     /experiment="EXISTENCE:direct assay:GO:0032040
                     small-subunit processome [PMID:12068309]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000447
                     endonucleolytic cleavage in ITS1 to separate SSU-rRNA from
                     5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript
                     (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15489292]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000472
                     endonucleolytic cleavage to generate mature 5'-end of
                     SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
                     [PMID:15489292]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000480
                     endonucleolytic cleavage in 5'-ETS of tricistronic rRNA
                     transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
                     [PMID:15489292]"
                     /note="Subunit of U3-containing Small Subunit (SSU)
                     processome complex; involved in production of 18S rRNA and
                     assembly of small ribosomal subunit"
                     /codon_start=1
                     /product="rRNA-processing protein UTP11"
                     /protein_id="DAA09058.1"
                     /db_xref="SGD:S000001582"
                     /translation="MAKLVHDVQKKQHRERSQLTSRSRYGFLEKHKDYVKRAQDFHRK
                     QSTLKVLREKAKERNPDEYYHAMHSRKTDAKGLLISSRHGDEEDESLSMDQVKLLKTQ
                     DSNYVRTLRQIELKKLEKGAKQLMFKSSGNHTIFVDSREKMNEFTPEKFFNTTSEMVN
                     RSENRLTKDQLAQDISNNRNASSIMPKESLDKKKLKKFKQVKQHLQRETQLKQVQQRM
                     DAQRELLKKGSKKKIVDSSGKISFKWKKQRKR"
     gene            256770..257843
                     /gene="MTC2"
                     /locus_tag="YKL098W"
     mRNA            256770..257843
                     /gene="MTC2"
                     /locus_tag="YKL098W"
                     /product="Mtc2p"
     CDS             256770..257843
                     /gene="MTC2"
                     /locus_tag="YKL098W"
                     /note="hypothetical protein; mtc2 is synthetically sick
                     with cdc13-1"
                     /codon_start=1
                     /product="Mtc2p"
                     /protein_id="DAA09059.1"
                     /db_xref="SGD:S000001581"
                     /translation="MGDHNLPDFQTCLKFSVTAKKSFLCMYRDSVSKEKLASSMPSTC
                     DIQLKRAINDAYPGGGIKVTVLNSTTASLDSLATTHVKEFEIVIIPDINSLLQPDQAK
                     LVKIMRDCTVAIEKAQSTRIFIGVVHWNNPVQPSGAAKDGDEAGKPAPKTRIFLPTSF
                     RMGAWLKHKFWFACAPPYLDFESSTESSINTRANNSIGMAEEEKQEPESKRSIILNEE
                     ANLNDVFVGSTVRRYILDIMVHLRTHRLTYNAKAGGVYTNSLDDVVLLSRLIGLHSGK
                     MFVSPSHVKEASRWYFPMHLELVQRSSMDSSLLYGSDPNLVDEMLEKLAKIKCEEVNE
                     FENPLFLESLVVKNVLSKVVPPV"
     gene            complement(258503..258913)
                     /locus_tag="YKL097C"
     mRNA            complement(258503..258913)
                     /locus_tag="YKL097C"
                     /product="hypothetical protein"
     CDS             complement(258503..258913)
                     /locus_tag="YKL097C"
                     /note="hypothetical protein; conserved across S.
                     cerevisiae strains; not conserved in closely related
                     Saccharomyces species"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA80310.1"
                     /db_xref="SGD:S000001580"
                     /translation="MFLFTFTILESEKLIIWPVPAVVLGVMAPKRAYSTPFGPWPGPA
                     ECLWNCPSELRQFSSCCLPLPKLRPPRPTFASLWRVVAAIAALFQVPWRRKTGVGKAI
                     FCIGCCCLAYQWRRTRYFAYKIMTGTCFMTDLAP"
     gene            complement(259073..259222)
                     /locus_tag="YKL096C-B"
     mRNA            complement(259073..259222)
                     /locus_tag="YKL096C-B"
                     /product="hypothetical protein"
     CDS             complement(259073..259222)
                     /locus_tag="YKL096C-B"
                     /note="hypothetical protein; identified by gene-trapping,
                     microarray-based expression analysis, and genome-wide
                     homology searching"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA09060.1"
                     /db_xref="SGD:S000028667"
                     /translation="MKLFILDYEKKRTKIGKGMARRELKMMNKKPDLYTIIVSYFSIF
                     SLFFF"
     gene            259253..259531
                     /gene="CWP2"
                     /locus_tag="YKL096W-A"
                     /gene_synonym="LPR1"
                     /gene_synonym="YKL097W-A"
     mRNA            259253..259531
                     /gene="CWP2"
                     /locus_tag="YKL096W-A"
                     /gene_synonym="LPR1"
                     /gene_synonym="YKL097W-A"
                     /product="Cwp2p"
     CDS             259253..259531
                     /gene="CWP2"
                     /locus_tag="YKL096W-A"
                     /gene_synonym="LPR1"
                     /gene_synonym="YKL097W-A"
                     /experiment="EXISTENCE:direct assay:GO:0005199 structural
                     constituent of cell wall [PMID:7768807]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
                     cell wall [PMID:11956747]"
                     /experiment="EXISTENCE:direct assay:GO:0031505 fungal-type
                     cell wall organization [PMID:7768807]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031505
                     fungal-type cell wall organization
                     [PMID:7768807|PMID:31537451]"
                     /note="Covalently linked cell wall mannoprotein; major
                     constituent of the cell wall; plays a role in stabilizing
                     the cell wall; involved in low pH resistance; precursor is
                     GPI-anchored"
                     /codon_start=1
                     /product="Cwp2p"
                     /protein_id="DAA09061.1"
                     /db_xref="SGD:S000001956"
                     /translation="MQFSTVASVAFVALANFVAAESAAAISQITDGQIQATTTATTEA
                     TTTAAPSSTVETVSPSSTETISQQTENGAAKAAVGMGAGALAAAAMLL"
     gene            261132..261851
                     /gene="CWP1"
                     /locus_tag="YKL096W"
                     /gene_synonym="YJU1"
     mRNA            261132..261851
                     /gene="CWP1"
                     /locus_tag="YKL096W"
                     /gene_synonym="YJU1"
                     /product="Cwp1p"
     CDS             261132..261851
                     /gene="CWP1"
                     /locus_tag="YKL096W"
                     /gene_synonym="YJU1"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005199 structural
                     constituent of cell wall [PMID:7768807]"
                     /experiment="EXISTENCE:direct assay:GO:0005628 prospore
                     membrane [PMID:18756268]"
                     /experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
                     cell wall [PMID:15781460|PMID:9335273]"
                     /experiment="EXISTENCE:direct assay:GO:0031505 fungal-type
                     cell wall organization [PMID:7768807]"
                     /experiment="EXISTENCE:direct assay:GO:0071597 cellular
                     birth scar [PMID:16672383]"
                     /experiment="EXISTENCE:genetic interaction:GO:0032120
                     ascospore-type prospore membrane formation
                     [PMID:18756268]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031505
                     fungal-type cell wall organization [PMID:7768807]"
                     /note="Cell wall mannoprotein that localizes to birth
                     scars of daughter cells; linked to a beta-1,3- and
                     beta-1,6-glucan heteropolymer through a phosphodiester
                     bond; required for propionic acid resistance"
                     /codon_start=1
                     /product="Cwp1p"
                     /protein_id="DAA09062.1"
                     /db_xref="SGD:S000001579"
                     /translation="MKFSTALSVALFALAKMVIADSEEFGLVSIRSGSDLQYLSVYSD
                     NGTLKLGSGSGSFEATITDDGKLKFDDDKYAVVNEDGSFKEGSESDAATGFSIKDGHL
                     NYKSSSGFYAIKDGSSYIFSSKQSDDATGVAIRPTSKSGSVAADFSPSDSSSSSSASA
                     SSASASSSTKHSSSIESVETSTTVETSSASSPTASVISQITDGQIQAPNTVYEQTENA
                     GAKAAVGMGAGALAVAAAYLL"
     gene            262277..263113
                     /gene="YJU2"
                     /locus_tag="YKL095W"
                     /gene_synonym="CWC16"
     mRNA            262277..263113
                     /gene="YJU2"
                     /locus_tag="YKL095W"
                     /gene_synonym="CWC16"
                     /product="mRNA splicing protein YJU2"
     CDS             262277..263113
                     /gene="YJU2"
                     /locus_tag="YKL095W"
                     /gene_synonym="CWC16"
                     /experiment="EXISTENCE:direct assay:GO:0000349 generation
                     of catalytic spliceosome for first transesterification
                     step [PMID:17515604]"
                     /experiment="EXISTENCE:direct assay:GO:0000384 first
                     spliceosomal transesterification activity [PMID:17515604]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0071006 U2-type
                     catalytic step 1 spliceosome [PMID:17515604]"
                     /note="Essential protein required for pre-mRNA splicing;
                     associates transiently with the spliceosomal NTC
                     ('nineteen complex') and acts after Prp2p to promote the
                     first catalytic reaction of splicing"
                     /codon_start=1
                     /product="mRNA splicing protein YJU2"
                     /protein_id="DAA09063.1"
                     /db_xref="SGD:S000001578"
                     /translation="MSERKAINKYYPPDYNPLEAEKLSRKMAKKLKTMNKSHASIRLM
                     TPFSMRCLECNEYIPKSRKFNGKKELLKEKYLDSIKIYRLTISCPRCANSIAFRTDPG
                     NSDYVMEVGGVRNYVPQKPNDDLNAKTAVESIDETLQRLVREKEMEQNEKMGIKEQAD
                     DKMDLLEKRLAKIQQEQEDDEELENLRKKNLEMSQRAEMINRSKHAQQEKAVTTDDLD
                     NLVDQVFDNHRQRTNKPGNNNDEKRTPLFNPTSTKGKIQKKSSVRTNPLGIVIKRGKS
                     LK"
     gene            263349..264290
                     /gene="YJU3"
                     /locus_tag="YKL094W"
     mRNA            263349..264290
                     /gene="YJU3"
                     /locus_tag="YKL094W"
                     /product="acylglycerol lipase"
     CDS             263349..264290
                     /gene="YJU3"
                     /locus_tag="YKL094W"
                     /EC_number="3.1.1.23"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:11914276]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005741
                     mitochondrial outer membrane [PMID:16407407]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005811 lipid
                     droplet [PMID:10515935|PMID:20554061|PMID:24868093]"
                     /experiment="EXISTENCE:direct assay:GO:0005886 plasma
                     membrane [PMID:16622836]"
                     /experiment="EXISTENCE:direct assay:GO:0016020 membrane
                     [PMID:20554061]"
                     /experiment="EXISTENCE:direct assay:GO:0017171 serine
                     hydrolase activity [PMID:14645503]"
                     /experiment="EXISTENCE:direct assay:GO:0071944 cell
                     periphery [PMID:26928762]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006641
                     triglyceride metabolic process [PMID:20554061]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0047372
                     acylglycerol lipase activity [PMID:20554061]"
                     /note="Monoglyceride lipase (MGL) that hydrolyzes fatty
                     acid ethyl esters; required for removal of toxic
                     metabolites in ethanol producing yeast cells; localizes to
                     lipid particles and membranes; member of the eukaryotic
                     serine hydrolase family; functional ortholog of mammalian
                     MGL"
                     /codon_start=1
                     /product="acylglycerol lipase"
                     /protein_id="DAA09064.1"
                     /db_xref="SGD:S000001577"
                     /translation="MAPYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVL
                     LIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF
                     VEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMY
                     NKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDF
                     MQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLY
                     PGARHSIFSLETDKVFNTVFNDMKQWLDKHTTTEAKP"
     gene            264789..265808
                     /gene="MBR1"
                     /locus_tag="YKL093W"
     mRNA            264789..265808
                     /gene="MBR1"
                     /locus_tag="YKL093W"
                     /product="Mbr1p"
     CDS             264789..265808
                     /gene="MBR1"
                     /locus_tag="YKL093W"
                     /experiment="EXISTENCE:mutant phenotype:GO:0009060 aerobic
                     respiration [PMID:8208248]"
                     /note="Protein involved in mitochondrial functions and
                     stress response; overexpression suppresses growth defects
                     of hap2, hap3, and hap4 mutants; MBR1 has a paralog, ISF1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Mbr1p"
                     /protein_id="DAA09065.1"
                     /db_xref="SGD:S000001576"
                     /translation="MRMEKTTDKPLSAGDMNDEYSRGPIDDIDCLNFFERAVQDPCCE
                     ACDTEDADEELRAKLSSFNFQPDSSPCNAKCQQTLNPLCKIDEALPAESELAPSRNGS
                     VSEANSDTNSIASTVHDPVDSKYGGMPSLRKAKTTSYFTSSSSNNTTMRNPLKKCNTN
                     INGLLVNGRSSSSSRQSIPELFSGACTKKKNNVLLKSETPNSEFSSNSLQHCNSRSFS
                     LPRSRSRSSAIAIPTHLYGLEKYVSPGLDTLTADPEESIERFSNNRPREISSCCPNDT
                     GDTSSSLSHSNTSSSLNFPLGTNTNQFHQPRQPVQQQQSSKPNFGAGRKKSFIEMSLA
                     SSFAG"
     gene            complement(266145..269459)
                     /gene="BUD2"
                     /locus_tag="YKL092C"
                     /gene_synonym="CLA2"
                     /gene_synonym="ERC25"
     mRNA            complement(266145..269459)
                     /gene="BUD2"
                     /locus_tag="YKL092C"
                     /gene_synonym="CLA2"
                     /gene_synonym="ERC25"
                     /product="GTPase-activating protein BUD2"
     CDS             complement(266145..269459)
                     /gene="BUD2"
                     /locus_tag="YKL092C"
                     /gene_synonym="CLA2"
                     /gene_synonym="ERC25"
                     /experiment="EXISTENCE:direct assay:GO:0000131 incipient
                     cellular bud site [PMID:10444589]"
                     /experiment="EXISTENCE:direct assay:GO:0005096 GTPase
                     activator activity [PMID:8371782]"
                     /experiment="EXISTENCE:direct assay:GO:0005628 prospore
                     membrane [PMID:24390141]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005935 cellular
                     bud neck [PMID:10444589|PMID:14562095]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007120 axial
                     cellular bud site selection [PMID:2065354|PMID:22558355]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007121 bipolar
                     cellular bud site selection [PMID:2065354]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007163
                     establishment or maintenance of cell polarity
                     [PMID:23783029]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030447
                     filamentous growth [PMID:15645503]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031578 mitotic
                     spindle orientation checkpoint signaling [PMID:22558355]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0036267
                     invasive filamentous growth [PMID:23783029]"
                     /note="GTPase activating factor for Rsr1p/Bud1p; plays a
                     role in spindle position checkpoint distinct from its role
                     in bud site selection; required for both axial and bipolar
                     budding patterns; mutants exhibit random budding in all
                     cell types; contains two PH-like domains"
                     /codon_start=1
                     /product="GTPase-activating protein BUD2"
                     /protein_id="DAA09066.1"
                     /db_xref="SGD:S000001575"
                     /translation="MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLN
                     DWKTHYLQITSTGALTHSIDELTADSTNIQPIIKHLQQCRIEIIKDKHSSFKDINANC
                     NFIIQVNTSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSK
                     KMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNG
                     MLDLLLQSDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFR
                     IENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKIS
                     NSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSNSSNPFWREEFQF
                     NELLRLTNSYLEIKQLFHDLNNKKRLRLIGKIKITQEIINDTRYNKETRLPIMDVDNK
                     NFQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQ
                     TSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSIL
                     TKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYK
                     RLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLR
                     FFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFID
                     KRHNDLLDYIDKMTQKKLDFNSKILNLSSTISRPKLAIEQTMLDDLPQIPYLLDKNLR
                     ETEFVNLIVNFSQEDMTKMEKYNHMDNGGKGELIEEEGLLSGSSLNLSVDKKDLDSPI
                     EVKPEIGELEFEKITENNTEIFGDDLMNLLKSDDVGSRSRDLDNGANSGIKFNSIIPK
                     AEEEKHAMKELEQESCLLYNRINHIRKRLSGYECASSTLFEDKKYSISLSHKIFYEEI
                     KEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDSYCKFLTIDVSDENPKS
                     SNKTSVHGTSSENGAKDDYLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNS
                     RKLTRWFKKKKETGGS"
     gene            complement(269718..270650)
                     /locus_tag="YKL091C"
                     /gene_synonym="SFH1"
     mRNA            complement(269718..270650)
                     /locus_tag="YKL091C"
                     /gene_synonym="SFH1"
                     /product="phosphatidylinositol/phosphatidylcholine-binding
                     protein"
     CDS             complement(269718..270650)
                     /locus_tag="YKL091C"
                     /gene_synonym="SFH1"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:12869188]"
                     /experiment="EXISTENCE:direct assay:GO:0031210
                     phosphatidylcholine binding [PMID:18243114]"
                     /experiment="EXISTENCE:direct assay:GO:0035091
                     phosphatidylinositol binding [PMID:18243114]"
                     /note="Putative phosphatidylinositol/phosphatidylcholine
                     transfer protein; possibly involved in lipid metabolism;
                     localizes to the nucleus; contains a CRAL/TRIO domain and
                     binds several lipids in a large-scale study; YKL091C has a
                     paralog, SEC14, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="phosphatidylinositol/phosphatidylcholine-binding
                     protein"
                     /protein_id="DAA09067.1"
                     /db_xref="SGD:S000001574"
                     /translation="MTTSILDTYPQICSPNALPGTPGNLTKEQEEALLQFRSILLEKN
                     YKERLDDSTLLRFLRARKFDINASVEMFVETERWREEYGANTIIEDYENNKEAEDKER
                     IKLAKMYPQYYHHVDKDGRPLYFEELGGINLKKMYKITTEKQMLRNLVKEYELFATYR
                     VPACSRRAGYLIETSCTVLDLKGISLSNAYHVLSYIKDVADISQNYYPERMGKFYIIH
                     SPFGFSTMFKMVKPFLDPVTVSKIFILGSSYKKELLKQIPIENLPVKYGGTSVLHNPN
                     DKFYYSDIGPWRDPRYIGPEGEIPNIFGKFTVTS"
     gene            271878..273209
                     /gene="CUE2"
                     /locus_tag="YKL090W"
     mRNA            271878..273209
                     /gene="CUE2"
                     /locus_tag="YKL090W"
                     /product="Cue2p"
     CDS             271878..273209
                     /gene="CUE2"
                     /locus_tag="YKL090W"
                     /experiment="EXISTENCE:direct assay:GO:0004519
                     endonuclease activity [PMID:31219035]"
                     /experiment="EXISTENCE:direct assay:GO:0006379 mRNA
                     cleavage [PMID:31219035]"
                     /experiment="EXISTENCE:direct assay:GO:0043130 ubiquitin
                     binding [PMID:12628920|PMID:12787503]"
                     /experiment="EXISTENCE:direct assay:GO:0070966
                     nuclear-transcribed mRNA catabolic process, no-go decay
                     [PMID:31219035]"
                     /note="Ubiquitin-binding endonuclease involved in mRNA
                     decay; recruited to stalled ribosomes to promote breakdown
                     of transcript body of nuclear-transcribed mRNA with stalls
                     in translation elongation; cleaves mRNA within A site of
                     colliding ribosome; has two CUE domains that bind
                     ubiquitin, which may facilitate intramolecular
                     monoubiquitination"
                     /codon_start=1
                     /product="Cue2p"
                     /protein_id="DAA09068.1"
                     /db_xref="SGD:S000001573"
                     /translation="MSMDNNDDHESKLSILMDMFPAISKSKLQVHLLENNNDLDLTIG
                     LLLKENDDKSTVDNELHQLYDMFPQLDCSVIKDQFVINEKSVESTISDLLNYETLQKL
                     KDNQANSPDSVKRNEKKNNWESTNDHIESIIKFTDAPKNIAQEYLAENGFDTVKAIIK
                     IILDYYDKRDFKKDVDTFKVKRSPNTTVRGGRVQSSTGLAHVLKKGKESANVAQESLK
                     RPRSYKHSLDSPQMVELNELVADNRDLKAINHEFLQKCLQFYDGDVVKVLNISSLLIE
                     DDKNITKTWNFDEGFTLTSRDNCKQHLPKFSTPQISRRNEVGNTYKLPLHDKETPEGA
                     VPVINNLFQTYRLDFHGFLPSEAVSTLKLALNKWWSKEVAERELNSHNINSYGSKVQF
                     VSPLIVVTGRGIHSIGGISKVRLQVKSFLEKNHYIFWEESSYFRIEGKKKK"
     gene            273394..275043
                     /gene="MIF2"
                     /locus_tag="YKL089W"
     mRNA            273394..275043
                     /gene="MIF2"
                     /locus_tag="YKL089W"
                     /product="Mif2p"
     CDS             273394..275043
                     /gene="MIF2"
                     /locus_tag="YKL089W"
                     /experiment="EXISTENCE:direct assay:GO:0000779 condensed
                     chromosome, centromeric region [PMID:9407032]"
                     /experiment="EXISTENCE:direct assay:GO:0019237 centromeric
                     DNA binding [PMID:9407032|PMID:18701705]"
                     /experiment="EXISTENCE:direct assay:GO:0044877
                     protein-containing complex binding [PMID:14581449]"
                     /experiment="EXISTENCE:genetic interaction:GO:0007059
                     chromosome segregation [PMID:22561346]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007052 mitotic
                     spindle organization [PMID:8408221]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007059
                     chromosome segregation [PMID:8408221]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051382
                     kinetochore assembly [PMID:18701705]"
                     /note="Centromeric CDEIII region binding protein;
                     nucleates kinetochore assembly; required for the
                     structural integrity of elongating spindles; copurifies
                     with subunits of the MIND complex and centromeric
                     nucleosome components (Cse4p and histones H2A, H2B, and
                     H4); phosphorylated by Ipl1p; orthologous to human
                     centromere constitutive-associated network (CCAN) subunit
                     CENP-C and fission yeast cnp3; localizes to the
                     kinetochore"
                     /codon_start=1
                     /product="Mif2p"
                     /protein_id="DAA09069.1"
                     /db_xref="SGD:S000001572"
                     /translation="MDYMKLGLKSRKTGIDVKQDIPKDEYSMENIDDFFKDDETSLIS
                     MRRKSRRKSSLFLPSTLNGDTKNVLPPFLQSYKSQDDEVVQSPSGKGDGSRRSSLLSH
                     QSNFLSPANDFEPIEEEPEQEENDIRGNDFATPITQKLSKPTYKRKYSTRYSLDTSES
                     PSVRLTPDRITNKNVYSDVPDLVADEDDDDRVNTSLNTSDNALLEDELEDDGFIPESE
                     EDGDYIESDSSLDSGSDSASDSDGDNTYQEVEEEAEVNTNDNEDDYIRRQASDVVRTD
                     SIIDRNGLRKSTRVKVAPLQYWRNEKIVYKRKSNKPVLDIDKIVTYDESEDEEEILAA
                     QRRKKQKKKPTPTRPYNYVPTGRPRGRPKKDPNAKENLIPEDPNEDIIERIESGGIEN
                     GEWLKHGILEANVKISDTKEETKDEIIAFAPNLSQTEQVKDTKDENFALEIMFDKHKE
                     YFASGILKLPAISGQKKLSNSFRTYITFHVIQGIVEVTVCKNKFLSVKGSTFQIPAFN
                     EYAIANRGNDEAKMFFVQVTVSEDANDDNDKELDSTFDTFG"
     gene            275283..276998
                     /gene="CAB3"
                     /locus_tag="YKL088W"
     mRNA            275283..276998
                     /gene="CAB3"
                     /locus_tag="YKL088W"
                     /product="phosphopantothenoylcysteine decarboxylase
                     complex subunit CAB3"
     CDS             275283..276998
                     /gene="CAB3"
                     /locus_tag="YKL088W"
                     /experiment="EXISTENCE:direct assay:GO:0004633
                     phosphopantothenoylcysteine decarboxylase activity
                     [PMID:19915539]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095|PMID:14690591]"
                     /experiment="EXISTENCE:direct assay:GO:0071513
                     phosphopantothenoylcysteine decarboxylase complex
                     [PMID:19915539]"
                     /experiment="EXISTENCE:direct assay:GO:1990143
                     CoA-synthesizing protein complex [PMID:23789928]"
                     /experiment="EXISTENCE:genetic interaction:GO:0015937
                     coenzyme A biosynthetic process
                     [PMID:19266201|PMID:19915539]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004633
                     phosphopantothenoylcysteine decarboxylase activity
                     [PMID:19915539]"
                     /note="Subunit of PPCDC and CoA-SPC complexes involved in
                     CoA biosynthesis; subunits of the
                     phosphopantothenoylcysteine decarboxylase (PPCDC) complex
                     are: Cab3p, Sis2p, Vhs3p, while the subunits of the
                     CoA-synthesizing protein complex (CoA-SPC) are: Cab2p,
                     Cab3p, Cab4p, and Cab5p as well as Sis2p and Vhs3p; null
                     mutant lethality is complemented by E. coli coaBC"
                     /codon_start=1
                     /product="phosphopantothenoylcysteine decarboxylase
                     complex subunit CAB3"
                     /protein_id="DAA09070.1"
                     /db_xref="SGD:S000001571"
                     /translation="MTDEKVNSDQNMNGKQGVNLISSLPTTQVPVSILTNKERRKSIH
                     DESNFERSDSHEDQSKSNSNRRNIYKNDYSTNLRDFSFANLKQNSERNKDGHEIQINT
                     SMPANTNGQQKRFSPSLPSAVSFTVPEVERLPYHRYSISNKPGKQQQQQEQLQQNQQQ
                     EEQQKAQLQEQNQRAKQQEEVKQIQEQVQKKQTERQQLIDEKERIANAIFKENTTNDG
                     TDIRKHSVSSGTSNSEDEVDSPSMEKNSIVHMPGDFIYFNPKSNASKPITAKAAPLSA
                     NNSTHKNKEVITAPTGPRVPFTEFFQKEDDKKFHILIGATGSVATIKVPLIIDKLFKI
                     YGPEKISIQLIVTKPAEHFLKGLKMSTHVKIWREEDAWVFDAVNKNDTSLSLNLILHH
                     ELRKWADIFLIAPLSANTLAKLANGICNNLLTSVMRDWSPLTPVLIAPAMNTFMYINP
                     MTKKHLTSLVQDYPFIQVLKPVEKVLICGDIGMGGMREWTDIVEIVRRRINEIRKARD
                     EETGDKEQEQEEQEGADNEDDDDEDDEEDEEDEEEEEALNETASDESNDEEDEEDEED
                     VKTEV"
     gene            complement(277189..277863)
                     /gene="CYT2"
                     /locus_tag="YKL087C"
     mRNA            complement(277189..277863)
                     /gene="CYT2"
                     /locus_tag="YKL087C"
                     /product="cytochrome c1 heme lyase CYT2"
     CDS             complement(277189..277863)
                     /gene="CYT2"
                     /locus_tag="YKL087C"
                     /EC_number="4.4.1.17"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005758
                     mitochondrial intermembrane space [PMID:7559417]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004408
                     holocytochrome-c synthase activity [PMID:1499554]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0018063
                     cytochrome c-heme linkage [PMID:1499554]"
                     /note="Cytochrome c1 heme lyase; involved in maturation of
                     cytochrome c1, which is a subunit of the mitochondrial
                     ubiquinol-cytochrome-c reductase; links heme covalently to
                     apocytochrome c1; human homolog HCCS can complement yeast
                     cyt2 null mutant"
                     /codon_start=1
                     /product="cytochrome c1 heme lyase CYT2"
                     /protein_id="DAA09071.1"
                     /db_xref="SGD:S000001570"
                     /translation="MMSSDQQGKCPVDEETKKLWLREHGNEAHPGATAPGNQLECSAN
                     PQDNDKTPEYHTTVDLSQSREVSTIPRTNSDRNWIYPSEKQFYEAMMKKNWDPNSDDM
                     KVVVPLHNSINERVWNYIKSWEDKQGGEACGGIKLTNFKGDSKKLTPRAWFRSRILHL
                     AKPFDRHDWQIDRCGKTVDYVIDFYSTDLNDANSQQQPLIYLDVRPKLNSFEGFRLRF
                     WKSLGF"
     gene            278281..278664
                     /gene="SRX1"
                     /locus_tag="YKL086W"
     mRNA            278281..278664
                     /gene="SRX1"
                     /locus_tag="YKL086W"
                     /product="sulfiredoxin"
     CDS             278281..278664
                     /gene="SRX1"
                     /locus_tag="YKL086W"
                     /EC_number="1.8.98.2"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0032542
                     sulfiredoxin activity [PMID:14586471]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0034599
                     cellular response to oxidative stress [PMID:14586471]"
                     /note="Sulfiredoxin; contributes to oxidative stress
                     resistance by reducing cysteine-sulfinic acid groups in
                     the peroxiredoxin Tsa1p, which is formed upon exposure to
                     oxidants; conserved in higher eukaryotes; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="sulfiredoxin"
                     /protein_id="DAA09072.1"
                     /db_xref="SGD:S000001569"
                     /translation="MSLQSNSVKPTEIPLSEIRRPLAPVLDPQKIDAMVATMKGIPTA
                     SKTCSLEQAEAAASAGELPPVDVLGVRVKGQTLYYAFGGCHRLQAYDRRARETQNAAF
                     PVRCRVLPATPRQIRMYLGSSLDIE"
     gene            279123..280127
                     /gene="MDH1"
                     /locus_tag="YKL085W"
     mRNA            279123..280127
                     /gene="MDH1"
                     /locus_tag="YKL085W"
                     /product="malate dehydrogenase MDH1"
     CDS             279123..280127
                     /gene="MDH1"
                     /locus_tag="YKL085W"
                     /EC_number="1.1.1.37"
                     /experiment="EXISTENCE:direct assay:GO:0003729 mRNA
                     binding [PMID:21124907]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:11502169|PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005759
                     mitochondrial matrix [PMID:9774331]"
                     /experiment="EXISTENCE:direct assay:GO:0030060 L-malate
                     dehydrogenase activity [PMID:1898005]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005739
                     mitochondrion [PMID:10777592]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006099
                     tricarboxylic acid cycle [PMID:3312168]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0009060 aerobic
                     respiration [PMID:3312168]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030060
                     L-malate dehydrogenase activity [PMID:10777592]"
                     /experiment="EXISTENCE:physical interaction:GO:0005739
                     mitochondrion [PMID:16962558]"
                     /note="Mitochondrial malate dehydrogenase; catalyzes
                     interconversion of malate and oxaloacetate; involved in
                     the tricarboxylic acid (TCA) cycle; phosphorylated;
                     mutation in human homolog MDH2 causes early-onset severe
                     encephalopathy"
                     /codon_start=1
                     /product="malate dehydrogenase MDH1"
                     /protein_id="DAA09073.1"
                     /db_xref="SGD:S000001568"
                     /translation="MLSRVAKRAFSSTVANPYKVTVLGAGGGIGQPLSLLLKLNHKVT
                     DLRLYDLKGAKGVATDLSHIPTNSVVKGFTPEEPDGLNNALKDTDMVLIPAGVPRKPG
                     MTRDDLFAINASIVRDLAAATAESAPNAAILVISNPVNSTVPIVAQVLKNKGVYNPKK
                     LFGVTTLDSIRAARFISEVENTDPTQERVNVIGGHSGITIIPLISQTNHKLMSDDKRH
                     ELIHRIQFGGDEVVKAKNGAGSATLSMAHAGAKFANAVLSGFKGERDVIEPSFVDSPL
                     FKSEGIEFFASPVTLGPDGIEKIHPIGELSSEEEEMLQKCKETLKKNIEKGVNFVASK
                     "
     gene            280509..280859
                     /gene="HOT13"
                     /locus_tag="YKL084W"
     mRNA            280509..280859
                     /gene="HOT13"
                     /locus_tag="YKL084W"
                     /product="Hot13p"
     CDS             280509..280859
                     /gene="HOT13"
                     /locus_tag="YKL084W"
                     /experiment="EXISTENCE:direct assay:GO:0005758
                     mitochondrial intermembrane space [PMID:15294910]"
                     /experiment="EXISTENCE:direct assay:GO:0008270 zinc ion
                     binding [PMID:18787558]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045041 protein
                     import into mitochondrial intermembrane space
                     [PMID:15294910]"
                     /note="Zinc-binding mitochondrial intermembrane space
                     (IMS) protein; involved in a disulfide relay system for
                     IMS import of cysteine-containing proteins; binds Mia40p
                     and stimulates its Erv1p-dependent oxidation, probably by
                     sequestering zinc"
                     /codon_start=1
                     /product="Hot13p"
                     /protein_id="DAA09074.1"
                     /db_xref="SGD:S000001567"
                     /translation="MIETAIYGKTVDDQSRCVHWHLPKDVIAIRFKCCDKYYACFECH
                     QELSSHPLEKYDLLDDANKHLIICGVCRHEMTFAEYYDYNSNLICPNCRSPFNPGCKL
                     HYHLYFQNPPPAMC"
     gene            complement(281025..282329)
                     /gene="RRP14"
                     /locus_tag="YKL082C"
     mRNA            complement(281025..282329)
                     /gene="RRP14"
                     /locus_tag="YKL082C"
                     /product="ribosome biosynthesis protein RRP14"
     CDS             complement(281025..282329)
                     /gene="RRP14"
                     /locus_tag="YKL082C"
                     /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
                     [PMID:11489916|PMID:17804645]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042273
                     ribosomal large subunit biogenesis
                     [PMID:17272295|PMID:17804645]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042274
                     ribosomal small subunit biogenesis [PMID:17272295]"
                     /note="Essential protein, constituent of 66S pre-ribosomal
                     particles; interacts with proteins involved in ribosomal
                     biogenesis and cell polarity; member of the SURF-6 family"
                     /codon_start=1
                     /product="ribosome biosynthesis protein RRP14"
                     /protein_id="DAA09075.1"
                     /db_xref="SGD:S000001565"
                     /translation="MSNSLEERLRANSSAFDGLLALIPAKYYYDEKSQEQWKAKKKTK
                     EQSKNDKLKKLDPEQRDDETSSTLEVMKKKEKDAKPVVLPGEKFKHMKMQKQKEATSK
                     VEGDSDLNVEVNDPMIIAPDEDEEEEEDIKVIFDDEGNEIPLESKKDTTEPDRSVEKK
                     SITEEEKLQRKKNLEALRSKLQAKISDMKSKRKAPGSREAILAQRKRKEELKKRKRLE
                     SEQEQDQDEIASDSDMEDIDSDLENNSKKRFKKGKKDSEINADGVMFQNIIFDDGARA
                     TSDLQRLRKAGRTKGPAKNDVKSHLKLLEAKKNKMEAKDELEQIKQKEKEKWQKAMLQ
                     AEGIKIRDDEKLLRKAIKRKEAQKRKSAIEWSERKRVVEDTISERQKRREENLRIRKD
                     NKGKKRNKQEKMKRKYVGSAVPKKRAGFEGRLKTGKKKGGPK"
     gene            282891..284455
                     /gene="TEF4"
                     /locus_tag="YKL081W"
                     /gene_synonym="EFC1"
     mRNA            join(282891..283095,283422..284455)
                     /gene="TEF4"
                     /locus_tag="YKL081W"
                     /gene_synonym="EFC1"
                     /product="translation elongation factor EF1B gamma"
     CDS             join(282891..283095,283422..284455)
                     /gene="TEF4"
                     /locus_tag="YKL081W"
                     /gene_synonym="EFC1"
                     /experiment="EXISTENCE:direct assay:GO:0005085
                     guanyl-nucleotide exchange factor activity [PMID:3528160]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0006414
                     translational elongation [PMID:3528160]"
                     /experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
                     stress granule [PMID:23451152|PMID:26777405]"
                     /note="Gamma subunit of translational elongation factor
                     eEF1B; stimulates the binding of aminoacyl-tRNA (AA-tRNA)
                     to ribosomes by releasing eEF1A (Tef1p/Tef2p) from the
                     ribosomal complex"
                     /codon_start=1
                     /product="translation elongation factor EF1B gamma"
                     /protein_id="DAA09076.1"
                     /db_xref="SGD:S000001564"
                     /translation="MSQGTLYINRSPRNYASEALISYFKLDVKIVDLEQSSEFASLFP
                     LKQAPAFLGPKGLKLTEALAIQFYLANQVADEKERARLLGSDVIEKSQILRWASLANS
                     DVMSNIARPFLSFKGLIPYNKKDVDACFVKIDNLAAVFDARLRDYTFVATENISLGDL
                     HAAGSWAFGLATILGPEWRAKHPHLMRWFNTVAASPIVKTPFAEVKLAEKALTYTPPK
                     KQKAEKPKAEKSKAEKKKDEAKPADDAAPAKKPKHPLEALGKSTFVLDDWKRKYSNDD
                     TRPVALPWFWEHYNPEEYSIWKVGYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGC
                     LVVYGENNNNGIVGAVMVRGQDFAPAFDVAPDWESYEYTKLDPTKEEDKEFVNNMWAW
                     DKPVVVNGEDKEIVDGKVLK"
     gene            283185..283279
                     /gene="SNR38"
                     /locus_tag="YNCK0009W"
     ncRNA           283185..283279
                     /ncRNA_class="snoRNA"
                     /gene="SNR38"
                     /locus_tag="YNCK0009W"
                     /product="SNR38"
                     /experiment="EXISTENCE:curator inference:GO:0005730
                     nucleolus [PMID:8674114]"
                     /experiment="EXISTENCE:curator inference:GO:0031428 box
                     C/D RNP complex [PMID:8674114]"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of large subunit (LSU) rRNA at position
                     G2815"
                     /db_xref="SGD:S000007301"
     gene            285030..286208
                     /gene="VMA5"
                     /locus_tag="YKL080W"
                     /gene_synonym="CSL5"
                     /gene_synonym="VAT3"
     mRNA            285030..286208
                     /gene="VMA5"
                     /locus_tag="YKL080W"
                     /gene_synonym="CSL5"
                     /gene_synonym="VAT3"
                     /product="H(+)-transporting V1 sector ATPase subunit C"
     CDS             285030..286208
                     /gene="VMA5"
                     /locus_tag="YKL080W"
                     /gene_synonym="CSL5"
                     /gene_synonym="VAT3"
                     /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
                     vacuole membrane [PMID:26928762]"
                     /note="Subunit C of the V1 peripheral membrane domain of
                     V-ATPase; part of the electrogenic proton pump found
                     throughout the endomembrane system; required for the V1
                     domain to assemble onto the vacuolar membrane; the V1
                     peripheral membrane domain of vacuolar H+-ATPase
                     (V-ATPase) has eight subunits"
                     /codon_start=1
                     /product="H(+)-transporting V1 sector ATPase subunit C"
                     /protein_id="DAA09077.1"
                     /db_xref="SGD:S000001563"
                     /translation="MATALYTANDFILISLPQNAQPVTAPGSKTDSWFNETLIGGRAF
                     VSDFKIPEFKIGSLDTLIVESEELSKVDNQIGASIGKIIEILQGLNETSTNAYRTLPI
                     NNMPVPEYLENFQWQTRKFKLDKSIKDLITLISNESSQLDADVRATYANYNSAKTNLA
                     AAERKKTGDLSVRSLHDIVKPEDFVLNSEHLTTVLVAVPKSLKSDFEKSYETLSKNVV
                     PASASVIAEDAEYVLFNVHLFKKNVQEFTTAAREKKFIPREFNYSEELIDQLKKEHDS
                     AASLEQSLRVQLVRLAKTAYVDVFINWFHIKALRVYVESVLRYGLPPHFNIKIIAVPP
                     KNLSKCKSELIDAFGFLGGNAFMKDKKGKINKQDTSLHQYASLVDTEYEPFVMYIINL
                     "
     gene            286603..288573
                     /gene="SMY1"
                     /locus_tag="YKL079W"
     mRNA            286603..288573
                     /gene="SMY1"
                     /locus_tag="YKL079W"
                     /product="Smy1p"
     CDS             286603..288573
                     /gene="SMY1"
                     /locus_tag="YKL079W"
                     /experiment="EXISTENCE:direct assay:GO:0000131 incipient
                     cellular bud site [PMID:8188749]"
                     /experiment="EXISTENCE:direct assay:GO:0005934 cellular
                     bud tip [PMID:8188749|PMID:9472039]"
                     /experiment="EXISTENCE:direct assay:GO:0005935 cellular
                     bud neck [PMID:8188749]"
                     /experiment="EXISTENCE:direct assay:GO:0043332 mating
                     projection tip [PMID:8188749|PMID:19053807]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006904
                     vesicle docking involved in exocytosis [PMID:27307583]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0003774 motor
                     activity [PMID:9472039]"
                     /experiment="EXISTENCE:physical interaction:GO:0005515
                     protein binding [PMID:27307583]"
                     /note="Kinesin-like myosin passenger-protein; interacts
                     with Myo2p and enhances its interaction with Sec4p during
                     transport of secretory vesicles; controls actin cable
                     structure and dynamics"
                     /codon_start=1
                     /product="Smy1p"
                     /protein_id="DAA09078.1"
                     /db_xref="SGD:S000001562"
                     /translation="MHWNIISKEQSSSSVSLPTLDSSEPCHIEVILRAIPEKGLQNNE
                     STFKIDPYENTVLFRTNNPLHETTKETHSTFQFDKVFDANATQEDVQKFLVHPIINDV
                     LNGYNGTVITYGPSFSGKSYSLIGSKESEGILPNICKTLFDTLEKNEETKGDSFSVSV
                     LAFEIYMEKTYDLLVPLPERKPLKLHRSSSKMDLEIKDICPAHVGSYEDLRSYIQAVQ
                     NVGNRMACGDKTERSRSHLVFQLHVEQRNRKDDILKNSSLYLVDLHGAEKFDKRTEST
                     LSQDALKKLNQSIEALKNTVRSLSMKERDSAYSAKGSHSSAYRESQLTEVLKDSLGGN
                     RKTKVILTCFLSNVPTTLSTLEFGDSIRQINNKVTDNTTGLNLKKKMDLFIQDMKIKD
                     DNYVAQINILKAEIDSLKSLHNKSLPEDDEKKMLENTKKENIKLKLQLDSITQLLSSS
                     TNEDPNNRIDEEVSEILTKRCEQIAQLELSFDRQMNSNSKLQQELEYKKSKEEALESM
                     NVRLLEQIQLQEREIQELLTTNAILKGELETHTKLTETRSERIKSLESSVKELSLNKS
                     AIPSPRRGSMSSSSGNTMLHIEEGSEISNSPWSANTSSKPLVWGARKVSSSSIATTGS
                     QESFVARPFKKGLNLHSIKVTSSTPKSPSSGS"
     gene            288845..291052
                     /gene="DHR2"
                     /locus_tag="YKL078W"
     mRNA            288845..291052
                     /gene="DHR2"
                     /locus_tag="YKL078W"
                     /product="RNA helicase"
     CDS             288845..291052
                     /gene="DHR2"
                     /locus_tag="YKL078W"
                     /EC_number="3.6.4.13"
                     /experiment="EXISTENCE:direct assay:GO:0003724 RNA
                     helicase activity [PMID:10982841]"
                     /experiment="EXISTENCE:direct assay:GO:0005730 nucleolus
                     [PMID:10982841]"
                     /experiment="EXISTENCE:direct assay:GO:0042254 ribosome
                     biogenesis [PMID:10982841]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000462
                     maturation of SSU-rRNA from tricistronic rRNA transcript
                     (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16449634]"
                     /note="Predominantly nucleolar DEAH-box ATP-dependent RNA
                     helicase; required for 18S rRNA synthesis"
                     /codon_start=1
                     /product="RNA helicase"
                     /protein_id="DAA09079.1"
                     /db_xref="SGD:S000001561"
                     /translation="MAANSNSRVASNHTSKKQKVRRNIHPFTNNTRIKRASKIVKFND
                     SGEGDHVSDQRSNKENVLTYKSLKSRASDLLKMRETLPVYQHKREIMSYIESNPVTVL
                     IGETGSGKSTQIPQFVLEKLYDTKKHGSIAVTQPRRVAAINLATRVAQEHGCKLGEQV
                     GYSVRFDNTTTTRTRLKYLTDGMLLRELMMNSDLREYSVIVIDEAHERTVLTDLILGF
                     LKSLIQGPRPDLRIIVMSATLQAEKFSEFFNNAPILFVEGRKFDVKQYYLKAPTDDIV
                     DAVIRCCIQINQGEELGDILCFLPGQEEIDKAVTIMEKIAKYVSDEAPVPLIVPYPLY
                     AALPAVQQSLVFAPIKGFKRKVVFSTNIAETSVTISGVKFVVDSGLRKVKVWRHQLGL
                     ATLLTVPISQASAMQRSGRAGRESEGKSFRLYCESDYVKLPKQSEPEIARSDVTSPVL
                     MLKRYGVDDLLNWTWFENPGKEAIVMGLQELYELGALDTRGKITKRGQQMALLPLQPH
                     LSSVLIKASEVGCLSQVIDIVSCLSVENLLLNPSPEERDEVNERRLSLCNAGKRYGDL
                     IMLKELFDIYFYELGKSQDASSERNDWCKGLCISIRGFKNVIRVRDQLRVYCKRLFSS
                     ISEEDEESKKIGEDGELISKILKCFLTGFIKNTAIGMPDRSYRTVSTGEPISIHPSSM
                     LFMNKSCPGIMYTEYVFTTKGYARNVSRIELSWLQEVVTNAAAVAKQKVSDSK"
     gene            291453..292631
                     /gene="PSG1"
                     /locus_tag="YKL077W"
     mRNA            291453..292631
                     /gene="PSG1"
                     /locus_tag="YKL077W"
                     /product="Psg1p"
     CDS             291453..292631
                     /gene="PSG1"
                     /locus_tag="YKL077W"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005794 Golgi
                     apparatus [PMID:28727280]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006605 protein
                     targeting [PMID:28727280]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051604 protein
                     maturation [PMID:28727280]"
                     /note="Protein that promotes the transport and maturation
                     of Pma1 with Exp1; cleaved specifically by Kex2p;
                     localizes to the Golgi apparatus and to the endoplasmic
                     reticulum in HTP studies"
                     /codon_start=1
                     /product="Psg1p"
                     /protein_id="DAA09080.1"
                     /db_xref="SGD:S000001560"
                     /translation="MRFHDSILIFFSLASLYQHVHGARQVVRPKEKMTTSEEVKPWLR
                     TVYGSQKELVTPTVIAGVTFSEKPEETPNPLKPWVSLEHDGRPKTIKPEINKGRTKKG
                     RPDYSTYFKTVSSHTYSYEELKAHNMGPNEVFVEEEYIDEDDTYVSLNPIVRCTPNLY
                     FNKGLAKDIRSEPFCTPYENSRWKVDKTYFVTWYTRFFTDENSGKVADKVRVHLSYVK
                     ENPVEKGNYKRDIPATFFSSEWIDNDNGLMPVEVRDEWLQDQFDRRIVVSVQPIYISD
                     EDFDPLQYGILLYITKGSKVFKPTKEQLALDDAGITNDQWYYVALSIPTVVVVFFVFM
                     YFFLYVNGKNRDFTDVTRKALNKKRRVLGKFSEMKKFKNMKNHKYTELPSYKKTSKQN
                     "
     gene            complement(292956..294308)
                     /locus_tag="YKL075C"
     mRNA            complement(292956..294308)
                     /locus_tag="YKL075C"
                     /product="hypothetical protein"
     CDS             complement(292956..294308)
                     /locus_tag="YKL075C"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042493
                     response to drug [PMID:16121259]"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm; proposed
                     to be involved in resistance to streptozotocin and
                     camptothecin"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA09081.1"
                     /db_xref="SGD:S000001558"
                     /translation="MAKDLLPKQAANEPSLKDCTCKRCLKLGASKEKKIRRKKKGEEK
                     RERHYGNRRKLTFNFLKHTNMENTNYDVITSVGYLNEKYGLKKSHYIEKFIKCIHRKI
                     NIDVSKITDAYVNSLNPWVKVKLFLLLVTLSEKGGPEYWLDKTDGEKNSEASSTDNSL
                     ENSTKGADSAGSTALRDEMVKSHKNLFPTLTEQIIQHNINQDFTESTYDEDYVFSSIW
                     ANFMEGLINHYLEKVIVPYSEMKVCQQLYKPMMKIISLYNEYNELMVKSEKNGFLPSL
                     QDSENVQGDKGEKESKDDAVSQERLERAQKLLWQAREDIPKTISKELTLLSEMYSTLS
                     ADEQDYELDEFVCCAEEYIELEYLPALVDVLFANCGTNNFWKIMLVLEPFFYYIEDVG
                     GDDDEDEDNVDNSEGDEESLLSRNVEGDDNVVERHFKPDPRVITLEKICEVAARQKWI
                     "
     gene            complement(294610..296193)
                     /gene="MUD2"
                     /locus_tag="YKL074C"
     mRNA            complement(294610..296193)
                     /gene="MUD2"
                     /locus_tag="YKL074C"
                     /product="Mud2p"
     CDS             complement(294610..296193)
                     /gene="MUD2"
                     /locus_tag="YKL074C"
                     /experiment="EXISTENCE:direct assay:GO:0000243 commitment
                     complex [PMID:7926772]"
                     /experiment="EXISTENCE:direct assay:GO:0003729 mRNA
                     binding [PMID:23222640]"
                     /experiment="EXISTENCE:direct assay:GO:0045131 pre-mRNA
                     branch point binding [PMID:7926772]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000348 mRNA
                     branch site recognition [PMID:18375978]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000243
                     commitment complex [PMID:7926772]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000348 mRNA
                     branch site recognition [PMID:9130720]"
                     /note="Protein involved in early pre-mRNA splicing;
                     component of the pre-mRNA-U1 snRNP complex, the commitment
                     complex; interacts with Msl5p/BBP splicing factor and
                     Sub2p; similar to metazoan splicing factor U2AF65"
                     /codon_start=1
                     /product="Mud2p"
                     /protein_id="DAA09082.1"
                     /db_xref="SGD:S000001557"
                     /translation="MADEKRLEDLRSKIMESIGKSEKDVVPIENKRFNTDNAVIDTHF
                     KRQKSDGELPKAPKSRNVSHSNNRGPSSIITMSTNRTTYEQTRAGPHRQSYRDASGRS
                     YNRENRYSSHNTGPQWNNNPYNRQRDERRGRNERFDRRGRNGNGNYDRFNYQRKNEGS
                     KFNGDRDKRQLQTNKYDMNYNSQNVMYPGSSFDSPAYYNMASSKANSRLVISGLSQSS
                     DPSIVARLKDLLENFISGLQKTESNAEDFKISNFYIGEGRPDHIIVEFSSQICSTMVL
                     ACRSFFNAKLGTFDLKWRRPNDYVQQLDHLVDFCRGTVIALENLENIGEGEDYRMKEL
                     FSSLNVTNGTAKPLFYKCSSNTNNTGKESEFTKCILLSFEVVTQDILDKLKPYKWFKP
                     NDGKISQVTSWITFQSLPNLVTQSVRVESRVLLLLNCLDPLDLKDETFITEIKETLKY
                     SIAGADTIKICQPGVDYRLNFENLASGAGNIYIKFKTLEAAKHAMEELPGTQFNDRTV
                     LCTYIDEDDFDMMEATQLS"
     gene            296430..299075
                     /gene="LHS1"
                     /locus_tag="YKL073W"
                     /gene_synonym="CER1"
                     /gene_synonym="SSI1"
     mRNA            296430..299075
                     /gene="LHS1"
                     /locus_tag="YKL073W"
                     /gene_synonym="CER1"
                     /gene_synonym="SSI1"
                     /product="Hsp70 family chaperone LHS1"
     CDS             296430..299075
                     /gene="LHS1"
                     /locus_tag="YKL073W"
                     /gene_synonym="CER1"
                     /gene_synonym="SSI1"
                     /experiment="EXISTENCE:direct assay:GO:0000774
                     adenyl-nucleotide exchange factor activity
                     [PMID:14704430]"
                     /experiment="EXISTENCE:direct assay:GO:0005524 ATP binding
                     [PMID:19759005]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005788 endoplasmic
                     reticulum lumen [PMID:8654361|PMID:8887673]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005524 ATP
                     binding [PMID:19759005]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006986
                     response to unfolded protein [PMID:8654361|PMID:8887673]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031204
                     posttranslational protein targeting to membrane,
                     translocation [PMID:8654361|PMID:8887673]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051082
                     unfolded protein binding
                     [PMID:10409721|PMID:8654361|PMID:8887673]"
                     /note="Molecular chaperone of the endoplasmic reticulum
                     lumen; involved in polypeptide translocation and folding;
                     nucleotide exchange factor for the ER lumenal Hsp70
                     chaperone Kar2p; regulated by the unfolded protein
                     response pathway"
                     /codon_start=1
                     /product="Hsp70 family chaperone LHS1"
                     /protein_id="DAA09083.1"
                     /db_xref="SGD:S000001556"
                     /translation="MRNVLRLLFLTAFVAIGSLAAVLGVDYGQQNIKAIVVSPQAPLE
                     LVLTPEAKRKEISGLSIKRLPGYGKDDPNGIERIYGSAVGSLATRFPQNTLLHLKPLL
                     GKSLEDETTVTLYSKQHPGLEMVSTNRSTIAFLVDNVEYPLEELVAMNVQEIANRANS
                     LLKDRDARTEDFVNKMSFTIPDFFDQHQRKALLDASSITTGIEETYLVSEGMSVAVNF
                     VLKQRQFPPGEQQHYIVYDMGSGSIKASMFSILQPEDTTQPVTIEFEGYGYNPHLGGA
                     KFTMDIGSLIENKFLETHPAIRTDELHANPKALAKINQAAEKAKLILSANSEASINIE
                     SLINDIDFRTSITRQEFEEFIADSLLDIVKPINDAVTKQFGGYGTNLPEINGVILAGG
                     SSRIPIVQDQLIKLVSEEKVLRNVNADESAVNGVVMRGIKLSNSFKTKPLNVVDRSVN
                     TYSFKLSNESELYDVFTRGSAYPNKTSILTNTTDSIPNNFTIDLFENGKLFETITVNS
                     GAIKNSYSSDKCSSGVAYNITFDLSSDRLFSIQEVNCICQSENDIGNSKQIKNKGSRL
                     AFTSEDVEIKRLSPSERSRLHEHIKLLDKQDKERFQFQENLNVLESNLYDARNLLMDD
                     EVMQNGPKSQVEELSEMVKVYLDWLEDASFDTDPEDIVSRIREIGILKKKIELYMDSA
                     KEPLNSQQFKGMLEEGHKLLQAIETHKNTVEEFLSQFETEFADTIDNVREEFKKIKQP
                     AYVSKALSTWEETLTSFKNSISEIEKFLAKNLFGEDLREHLFEIKLQFDMYRTKLEEK
                     LRLIKSGDESRLNEIKKLHLRNFRLQKRKEEKLKRKLEQEKSRNNNETESTVINSADD
                     KTTIVNDKTTESNPSSEEDILHDEL"
     gene            299582..301882
                     /gene="STB6"
                     /locus_tag="YKL072W"
     mRNA            299582..301882
                     /gene="STB6"
                     /locus_tag="YKL072W"
                     /product="Stb6p"
     CDS             299582..301882
                     /gene="STB6"
                     /locus_tag="YKL072W"
                     /note="Protein that binds Sin3p in a two-hybrid assay;
                     STB6 has a paralog, STB2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Stb6p"
                     /protein_id="DAA09084.1"
                     /db_xref="SGD:S000001555"
                     /translation="MQLEATHQKENHLSPLASFIFPDFRALFNIGFNLYSNINYKEVD
                     INGFEIYIVEQWAAQRKISTLITSYTGNLQDTISAVEVALPEDPEEWPCCLKKYHEEL
                     LKFSSPKKTAKGTLFVTNLSSFKSTLNLLHVECGNLKKIWKNFKTNYDLKRLHCGGRS
                     AQLLKKTPSASIAKFAQLYKFPNSAFSHEITSDFQQPSLQNDNSSISSIENIPVNHCP
                     VVELTTLVQISLSYFALFEYKKERDGLLCNGTKQSLEKWWEIYGKRYHGIDKPKNETI
                     LGPTTVASLLSLVLTCYFKLMVEDCMSAKDPFDEEEFYSGLYAFQKKYGLSKNNKQTS
                     LDELTIDKLFEVSSKTSNKDIFKFKKVVKSTVQDMTGKGNFMHLSNEILTTDLDTLVK
                     NIHGGSLGKLWKGRSASRKETCMVWERKTFLSFKFERGDPSLQLENNELFYGTSVPSE
                     QLTTSNKEDSDTQPTKRNSIYDIANGSKSSLSISSMFCNYDETRYKSTNNLNRAYRGE
                     YFRRNSIPFCNDGIHDTKKISADLNKIDGLYRCNSYSEVQNAIELWSLPFDSSVIRLA
                     RDLLKIQSLMSVQRQLDEIRDGYLGKNSQRSYQNDLMFRQSLNKLQEMCERCKRGSNE
                     FHWEYGNMQNKQQILESEKKDMKSLSSKLKYNVRILDRRVRDVEASVDHFDRKLEDVR
                     KKLLEQNNSKDISMALESPCDKFEFDSFMDSIVQSQQTKYEGLCFKILDKKSLRKLKK
                     EFWKWSTWTFDTFLYKNRPNKEKDTL"
     repeat_region   complement(302334..302625)
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000007052"
     gene            302918..303023
                     /locus_tag="YNCK0010W"
     tRNA            join(302918..302953,302988..303023)
                     /locus_tag="YNCK0010W"
                     /product="tRNA-Trp"
                     /experiment="EXISTENCE:curator inference:GO:0005829
                     cytosol [PMID:9023104]"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /note="Tryptophan tRNA (tRNA-Trp), predicted by
                     tRNAscan-SE analysis"
                     /db_xref="SGD:S000006774"
     gene            305114..305884
                     /gene="OSI1"
                     /locus_tag="YKL071W"
     mRNA            305114..305884
                     /gene="OSI1"
                     /locus_tag="YKL071W"
                     /product="Osi1p"
     CDS             305114..305884
                     /gene="OSI1"
                     /locus_tag="YKL071W"
                     /experiment="EXISTENCE:direct assay:GO:0004022 alcohol
                     dehydrogenase (NAD+) activity [PMID:29034432]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0110095
                     cellular detoxification of aldehyde [PMID:19854918]"
                     /note="NADH-dependent aldehyde reductase; involved in
                     detoxification of furfural; expression is upregulated in
                     cells treated with the aldehydes furfural and
                     glycolaldehyde, the mycotoxin patulin, and also the
                     quinone methide triterpene celastrol; green fluorescent
                     protein (GFP)-fusion protein localizes to the cytoplasm"
                     /codon_start=1
                     /product="Osi1p"
                     /protein_id="DAA09085.1"
                     /db_xref="SGD:S000001554"
                     /translation="MNTSSRITYFIIGGSRGIGFNLVKILSASTGNTVITSIRGSPSL
                     PKNKQVEDLAKIRKNIHIVQLDLTKDESIGNIADEIKKTPFFLGIDIFIACSAVSDSY
                     YKVLETPKSVWLNHYSTNALGPILALQKVYPLLLLKKTRKIFFISSVAGSINAFVPLS
                     VSAYGQSKAALNYAVKTLSFELKPEGFTVVAFHPGMVSTDMGQYGLDHFKEKNIDISG
                     VNIITPEESASALIDVFRKILPEDNGKFFNYDGSEGVF"
     gene            306211..306720
                     /locus_tag="YKL070W"
     mRNA            306211..306720
                     /locus_tag="YKL070W"
                     /product="hypothetical protein"
     CDS             306211..306720
                     /locus_tag="YKL070W"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:14576278|PMID:16823961]"
                     /note="hypothetical protein; expression induced in cells
                     treated with mycotoxins patulin or citrinin; the
                     authentic, non-tagged protein is detected in highly
                     purified mitochondria in high-throughput studies"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA09086.1"
                     /db_xref="SGD:S000001553"
                     /translation="MYIPKHFESMELSRYKLSKKPPLGTLFSSKASRQGFFGWRTSSN
                     KDDPDFGMCASHIPFVFVEFDNGEHKLIAHLARKNKHVEMLERVQKCLVVFQSVDSYI
                     SPAWFPMKKKTHKFVPTWDFAAVHVYGTPRIIRDDKDWLINMLSTLTDQEEEKRPEGE
                     NVRSKVERF"
     gene            307285..307827
                     /locus_tag="YKL069W"
                     /gene_synonym="YKG9"
     mRNA            307285..307827
                     /locus_tag="YKL069W"
                     /gene_synonym="YKG9"
                     /product="L-methionine (R)-S-oxide reductase"
     CDS             307285..307827
                     /locus_tag="YKL069W"
                     /gene_synonym="YKG9"
                     /EC_number="1.8.4.14"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:14562095|PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095|PMID:22842922]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0070191
                     methionine-R-sulfoxide reductase activity [PMID:19049972]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0034599
                     cellular response to oxidative stress [PMID:19049972]"
                     /note="Methionine-R-sulfoxide reductase; reduces the R
                     enantiomer of free Met-SO, in contrast to Ycl033Cp which
                     reduces Met-R-SO in a peptide linkage; has a role in
                     protection against oxidative stress; relative distribution
                     to the nucleus increases upon DNA replication stress"
                     /codon_start=1
                     /product="L-methionine (R)-S-oxide reductase"
                     /protein_id="DAA09087.1"
                     /db_xref="SGD:S000001552"
                     /translation="MGSSTGFHHADHVNYSSNLNKEEILEQLLLSYEGLSDGQVNWVC
                     NLSNASSLIWHAYKSLAVDINWAGFYVTQASEENTLILGPFQGKVACQMIQFGKGVCG
                     TAASTKETQIVPDVNKYPGHIACDGETKSEIVVPIISNDGKTLGVIDIDCLDYEGFDH
                     VDKEFLEKLAKLINKSCVFK"
     gene            complement(308144..308217)
                     /locus_tag="YNCK0011C"
     tRNA            complement(308144..308217)
                     /locus_tag="YNCK0011C"
                     /product="tRNA-Val"
                     /experiment="EXISTENCE:curator inference:GO:0005829
                     cytosol [PMID:9023104]"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006760"
     gene            309206..309442
                     /locus_tag="YKL068W-A"
     mRNA            309206..309442
                     /locus_tag="YKL068W-A"
                     /product="hypothetical protein"
     CDS             309206..309442
                     /locus_tag="YKL068W-A"
                     /note="hypothetical protein; identified by homology to
                     Ashbya gossypii"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA09088.1"
                     /db_xref="SGD:S000028524"
                     /translation="MQANHSVSYLYESSTSKRSNGLFSQTQKQGSFQKALSQTQEEIE
                     DEDLMVDLNTGSLTPVKLKYWTQMSAMTEKFGKL"
     gene            310199..313078
                     /gene="NUP100"
                     /locus_tag="YKL068W"
                     /gene_synonym="NSP100"
     mRNA            310199..313078
                     /gene="NUP100"
                     /locus_tag="YKL068W"
                     /gene_synonym="NSP100"
                     /product="FG-nucleoporin NUP100"
     CDS             310199..313078
                     /gene="NUP100"
                     /locus_tag="YKL068W"
                     /gene_synonym="NSP100"
                     /experiment="EXISTENCE:direct assay:GO:0005643 nuclear
                     pore [PMID:10684247|PMID:8195299]"
                     /experiment="EXISTENCE:direct assay:GO:0017056 structural
                     constituent of nuclear pore [PMID:19098896]"
                     /experiment="EXISTENCE:direct assay:GO:0044613 nuclear
                     pore central transport channel [PMID:18046406]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006606
                     protein import into nucleus [PMID:20647373]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006607
                     NLS-bearing protein import into nucleus [PMID:15039779]"
                     /experiment="EXISTENCE:genetic interaction:GO:0017056
                     structural constituent of nuclear pore [PMID:20647373]"
                     /experiment="EXISTENCE:genetic interaction:GO:0036228
                     protein localization to nuclear inner membrane
                     [PMID:21659568]"
                     /experiment="EXISTENCE:genetic interaction:GO:0045893
                     positive regulation of transcription, DNA-templated
                     [PMID:15817685]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000973
                     posttranscriptional tethering of RNA polymerase II gene
                     DNA at nuclear periphery [PMID:20932479]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0017056
                     structural constituent of nuclear pore [PMID:17418788]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031990 mRNA
                     export from nucleus in response to heat stress
                     [PMID:18258809]"
                     /experiment="EXISTENCE:mutant phenotype:GO:2000238
                     regulation of tRNA export from nucleus [PMID:27932586]"
                     /experiment="EXISTENCE:physical interaction:GO:0006406
                     mRNA export from nucleus [PMID:11104765]"
                     /experiment="EXISTENCE:physical interaction:GO:0017056
                     structural constituent of nuclear pore
                     [PMID:12917401|PMID:17803941|PMID:19098896|PMID:17418788]"
                     /note="FG-nucleoporin component of central core of the
                     nuclear pore complex; contributes directly to
                     nucleocytoplasmic transport and maintenance of the nuclear
                     pore complex (NPC) permeability barrier and is involved in
                     gene tethering at the nuclear periphery; NUP100 has a
                     paralog, NUP116, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="FG-nucleoporin NUP100"
                     /protein_id="DAA09089.1"
                     /db_xref="SGD:S000001551"
                     /translation="MFGNNRPMFGGSNLSFGSNTSSFGGQQSQQPNSLFGNSNNNNNS
                     TSNNAQSGFGGFTSAAGSNSNSLFGNNNTQNNGAFGQSMGATQNSPFGSLNSSNASNG
                     NTFGGSSSMGSFGGNTNNAFNNNSNSTNSPFGFNKPNTGGTLFGSQNNNSAGTSSLFG
                     GQSTSTTGTFGNTGSSFGTGLNGNGSNIFGAGNNSQSNTTGSLFGNQQSSAFGTNNQQ
                     GSLFGQQSQNTNNAFGNQNQLGGSSFGSKPVGSGSLFGQSNNTLGNTTNNRNGLFGQM
                     NSSNQGSSNSGLFGQNSMNSSTQGVFGQNNNQMQINGNNNNSLFGKANTFSNSASGGL
                     FGQNNQQQGSGLFGQNSQTSGSSGLFGQNNQKQPNTFTQSNTGIGLFGQNNNQQQQST
                     GLFGAKPAGTTGSLFGGNSSTQPNSLFGTTNVPTSNTQSQQGNSLFGATKLTNMPFGG
                     NPTANQSGSGNSLFGTKPASTTGSLFGNNTASTTVPSTNGLFGNNANNSTSTTNTGLF
                     GAKPDSQSKPALGGGLFGNSNSNSSTIGQNKPVFGGTTQNTGLFGATGTNSSAVGSTG
                     KLFGQNNNTLNVGTQNVPPVNNTTQNALLGTTAVPSLQQAPVTNEQLFSKISIPNSIT
                     NPVKATTSKVNADMKRNSSLTSAYRLAPKPLFAPSSNGDAKFQKWGKTLERSDRGSST
                     SNSITDPESSYLNSNDLLFDPDRRYLKHLVIKNNKNLNVINHNDDEASKVKLVTFTTE
                     SASKDDQASSSIAASKLTEKAHSPQTDLKDDHDESTPDPQSKSPNGSTSIPMIENEKI
                     SSKVPGLLSNDVTFFKNNYYISPSIETLGNKSLIELRKINNLVIGHRNYGKVEFLEPV
                     DLLNTPLDTLCGDLVTFGPKSCSIYENCSIKPEKGEGINVRCRVTLYSCFPIDKETRK
                     PIKNITHPLLKRSIAKLKENPVYKFESYDPVTGTYSYTIDHPVLT"
     gene            complement(313401..313472)
                     /locus_tag="YNCK0012C"
     tRNA            complement(313401..313472)
                     /locus_tag="YNCK0012C"
                     /product="tRNA-His"
                     /experiment="EXISTENCE:curator inference:GO:0005829
                     cytosol [PMID:9023104]"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /experiment="EXISTENCE:direct assay:GO:0030371 translation
                     repressor activity [PMID:27609601]"
                     /experiment="EXISTENCE:direct assay:GO:0043022 ribosome
                     binding [PMID:27609601]"
                     /experiment="EXISTENCE:direct assay:GO:0043555 regulation
                     of translation in response to stress [PMID:27609601]"
                     /note="Histidine tRNA (tRNA-His), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006598"
     repeat_region   complement(313602..313919)
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000007053"
     repeat_region   314193..314524
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000007057"
     gene            314812..315273
                     /gene="YNK1"
                     /locus_tag="YKL067W"
                     /gene_synonym="NDK1"
     mRNA            314812..315273
                     /gene="YNK1"
                     /locus_tag="YKL067W"
                     /gene_synonym="NDK1"
                     /product="nucleoside diphosphate kinase"
     CDS             314812..315273
                     /gene="YNK1"
                     /locus_tag="YKL067W"
                     /gene_synonym="NDK1"
                     /EC_number="2.7.4.6"
                     /experiment="EXISTENCE:direct assay:GO:0004550 nucleoside
                     diphosphate kinase activity [PMID:12472466]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0005758
                     mitochondrial intermembrane space [PMID:12472466]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:12472466]"
                     /experiment="EXISTENCE:direct assay:GO:0006165 nucleoside
                     diphosphate phosphorylation [PMID:1659321]"
                     /experiment="EXISTENCE:direct assay:GO:0009142 nucleoside
                     triphosphate biosynthetic process [PMID:1659321]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006974
                     cellular response to DNA damage stimulus [PMID:18983998]"
                     /note="Nucleoside diphosphate kinase; catalyzes the
                     transfer of gamma phosphates from nucleoside
                     triphosphates, usually ATP, to nucleoside diphosphates by
                     a mechanism that involves formation of an
                     autophosphorylated enzyme intermediate; protein abundance
                     increases in response to DNA replication stress"
                     /codon_start=1
                     /product="nucleoside diphosphate kinase"
                     /protein_id="DAA09090.1"
                     /db_xref="SGD:S000001550"
                     /translation="MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVKA
                     DDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAP
                     GTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE"
     gene            315954..316175
                     /gene="DPC7"
                     /locus_tag="YKL065W-A"
     mRNA            315954..316175
                     /gene="DPC7"
                     /locus_tag="YKL065W-A"
                     /product="Dpc7p"
     CDS             315954..316175
                     /gene="DPC7"
                     /locus_tag="YKL065W-A"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /note="hypothetical protein; SWAT-GFP fusion protein
                     localizes to endoplasmic reticulum (ER) while mCherry
                     fusion localizes to both ER and vacuole"
                     /codon_start=1
                     /product="Dpc7p"
                     /protein_id="DAA09091.1"
                     /db_xref="SGD:S000113563"
                     /translation="MRSNILKLLQRTSRRYVSSKDFEPVIGSNPKKQTSRLMVGSVGV
                     MIPVLLYLFYKNDSKHSEIKKIYQNEKKI"
     gene            complement(316437..317057)
                     /gene="YET1"
                     /locus_tag="YKL065C"
     mRNA            complement(316437..317057)
                     /gene="YET1"
                     /locus_tag="YKL065C"
                     /product="Yet1p"
     CDS             complement(316437..317057)
                     /gene="YET1"
                     /locus_tag="YKL065C"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:20378542|PMID:14562095|PMID:26928762]"
                     /note="Endoplasmic reticulum transmembrane protein; may
                     interact with ribosomes, based on co-purification
                     experiments; homolog of human BAP31 protein; YET1 has a
                     paralog, YET2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Yet1p"
                     /protein_id="DAA09092.2"
                     /db_xref="SGD:S000001548"
                     /translation="MSLYFTTLFLLLTVEMVMLFIFVLPLPFRIRRGIFSTYNQLTAK
                     QQIKTIIFITGCLVGLLFIDSWKRSQIRVSLYHNDNSGSIGSSAVTPIQALASRAYNQ
                     RNMYISGFILYFSICIPTVMSIVKRLVKYQGLINEQEKQKLNKPSSNSKKDSNEADST
                     KLQEELRKKQISLEGLQKQVKNLEKYFDEKNQPGNVAAAEASKKGN"
     gene            317764..320673
                     /gene="MNR2"
                     /locus_tag="YKL064W"
     mRNA            317764..320673
                     /gene="MNR2"
                     /locus_tag="YKL064W"
                     /product="putative Mg(2+) transporter MNR2"
     CDS             317764..320673
                     /gene="MNR2"
                     /locus_tag="YKL064W"
                     /experiment="EXISTENCE:direct assay:GO:0000329 fungal-type
                     vacuole membrane
                     [PMID:19720860|PMID:19001347|PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:1990816
                     vacuole-mitochondrion membrane contact site
                     [PMID:25026036]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0010961
                     cellular magnesium ion homeostasis [PMID:19720860]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015095
                     magnesium ion transmembrane transporter activity
                     [PMID:19720860]"
                     /note="Vacuolar membrane protein required for magnesium
                     homeostasis; putative magnesium transporter; has
                     similarity to Alr1p and Alr2p, which mediate influx of
                     Mg2+ and other divalent cations; localizes to sites of
                     contact between the vacuole and mitochondria (vCLAMPs)"
                     /codon_start=1
                     /product="putative Mg(2+) transporter MNR2"
                     /protein_id="DAA09093.1"
                     /db_xref="SGD:S000001547"
                     /translation="MSTDNSQKDEGVPLLSPYSSSPQLRKKKRNQKRRKDKFVGHLKS
                     DSRRPTQLLHDNLQHNHGQITDFDQIDSWGMLHESDSTSNDIIKSEDPSLKGAFIDHR
                     PSMSQPREGPQSVSSTVQPQPIMKFSTPSYKKPAGLRPSDQNRSLVSDLSPSELESWL
                     KRRKSVHKSFVDENSPTDRRQSNANNDVVIDVDALMNHVNNNASTGVNDNSKRRKKKR
                     GSDDSSNKNSKSTSSDSNDEEDEYNSRPSSSLSSNNSSLDDVCLVLDDEGSEVPKAWP
                     DCTVLEEFSKEETERLRSQAIQDAEAFHFQYDEDEEDGTSNEDGILFSKPIVTNIDVP
                     ELGNRRVNETENLKNGRLRPKRIAPWHLIQRPMVLGSNSTKDSKSRIQSGLQDNLLVG
                     RNIQYPPHIISNNPEHFRFTYFRVDLDSTVHSPTISGLLQPGQKFQDLFVASIYSQDN
                     SAGHIKTHPNSPTPGIKAETVSQLQGLTAKNPSTLSSMSVANIEDVPPFWLDVSNPTE
                     EEMKILSKAFGIHPLTTEDIFLGEVREKVELFRDYYLICFRSFDIVAEKHVRRRRKEK
                     QESATLDHESISRRKSQAYGATMSNESNANNNNSTSNASRSKWLPSILRARRRSSANR
                     TTNTSSSSYKRRVKSEKKKMEENEKFKRKSGDRHKPREGELEPLNVYIIVFRTGVLTF
                     HFAPTPHPINVRRRARLLKDYLNVTSDWIAYALIDDITDAFAPMIELIEDEVYEIEDA
                     ILKMHQSDDSSDSDSSDSDSDSGASDEDAFPFDVYSKKTSYSSAKSSVSSRSMSTSEA
                     SFNANLIGWKRKGDMLRRIGECRKRVMSILRLLGSKADVIKGFAKRYNEQWEASPQSE
                     IAMYLGDIQDHIVTMVSSLNHYEKLLSRSHSNYLAQINIDMTKVNNDMNDVLGKITIL
                     GTIVLPMNVITGLWGMNVIVPGQYRDSLTWFIGIVLFMCMLACSAYMYTKRRFGF"
     gene            complement(321015..321518)
                     /locus_tag="YKL063C"
     mRNA            complement(321015..321518)
                     /locus_tag="YKL063C"
                     /product="hypothetical protein"
     CDS             complement(321015..321518)
                     /locus_tag="YKL063C"
                     /experiment="EXISTENCE:direct assay:GO:0005794 Golgi
                     apparatus [PMID:14562095]"
                     /note="hypothetical protein; green fluorescent protein
                     (GFP)-fusion protein localizes to the Golgi"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA09094.1"
                     /db_xref="SGD:S000001546"
                     /translation="MQGDIRRKKDLLPRYKTGSKYNSRRRGGYLTTPMKKIIVYIILL
                     CGVYFVIKVAYSDLNKETEIKLESHSSDVSASASDHTNIAAGGAADATNNKQPQQAKV
                     PKEKFNNEVAKQQEVKNLENDLKPQIDSEKQKQINKDKKEQKQQLQKEKQDLAKENLA
                     NNEILDN"
     gene            323228..325120
                     /gene="MSN4"
                     /locus_tag="YKL062W"
     mRNA            323228..325120
                     /gene="MSN4"
                     /locus_tag="YKL062W"
                     /product="stress-responsive transcriptional activator
                     MSN4"
     CDS             323228..325120
                     /gene="MSN4"
                     /locus_tag="YKL062W"
                     /experiment="EXISTENCE:direct assay:GO:0000981 DNA-binding
                     transcription factor activity, RNA polymerase II-specific
                     [PMID:23435728|PMID:27637775]"
                     /experiment="EXISTENCE:direct assay:GO:0000987
                     cis-regulatory region sequence-specific DNA binding
                     [PMID:8321194|PMID:8641288]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:12732613|PMID:9472026]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:12732613|PMID:9472026]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006338
                     chromatin remodeling [PMID:18070923]"
                     /experiment="EXISTENCE:genetic interaction:GO:0045944
                     positive regulation of transcription by RNA polymerase II
                     [PMID:20398213|PMID:27637775|PMID:10652100|PMID:11102521|P
                     MID:11179418|PMID:15053871|PMID:15483057|PMID:15922872|PMI
                     D:16710843|PMID:17055490|PMID:17150183|PMID:17914901|PMID:
                     19073887|PMID:21749328|PMID:26947009|PMID:8641288|PMID:197
                     02872]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000981
                     DNA-binding transcription factor activity, RNA polymerase
                     II-specific [PMID:27637775|PMID:8650168]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045944
                     positive regulation of transcription by RNA polymerase II
                     [PMID:11102521|PMID:15922872]"
                     /experiment="EXISTENCE:physical interaction:GO:0005515
                     protein binding [PMID:27637775]"
                     /note="Stress-responsive transcriptional activator;
                     activated in stochastic pulses of nuclear localization in
                     response to various stress conditions; binds DNA at stress
                     response elements of responsive genes, inducing gene
                     expression; involved in diauxic shift"
                     /codon_start=1
                     /product="stress-responsive transcriptional activator
                     MSN4"
                     /protein_id="DAA09095.1"
                     /db_xref="SGD:S000001545"
                     /translation="MLVFGPNSSFVRHANKKQEDSSIMNEPNGLMDPVLSTTNVSATS
                     SNDNSANNSISSPEYTFGQFSMDSPHRTDATNTPILTATTNTTANNSLMNLKDTASLA
                     TNWKWKNSNNAQFVNDGEKQSSNANGKKNGGDKIYSSVATPQALNDELKNLEQLEKVF
                     SPMNPINDSHFNENIELSPHQHATSPKTNLLEAEPSIYSNLFLDARLPNNANSTTGLN
                     DNDYNLDDTNNDNTNSMQSILEDFVSSEEALKFMPDAGRDARRYSEVVTSSFPSMTDS
                     RNSISHSIEFWNLNHKNSSNSKPTQQIIPEGTATTERRGSTISPTTTINNSNPNFKLL
                     DHDVSQALSGYSMDFSKDSGITKPKSISSSLNRISHSSSTTRQQRASLPLIHDIESFA
                     NDSVMANPLSDSASFLSEENEDDAFGALNYNSLDATTMSAFDNNVDPFNILKSSPAQD
                     QQFIKPSMMLSDNASAAAKLATSGVDNITPTPAFQRRSYDISMNSSFKILPTSQAHHA
                     AQHHQQQPTKQATVSPNTRRRKSSSVTLSPTISHNNNNGKVPVQPRKRKSITTIDPNN
                     YDKNKPFKCKDCEKAFRRSEHLKRHIRSVHSTERPFACMFCEKKFSRSDNLSQHLKTH
                     KKHGDF"
     gene            325771..326112
                     /gene="BLI1"
                     /locus_tag="YKL061W"
     mRNA            325771..326112
                     /gene="BLI1"
                     /locus_tag="YKL061W"
                     /product="Bli1p"
     CDS             325771..326112
                     /gene="BLI1"
                     /locus_tag="YKL061W"
                     /experiment="EXISTENCE:direct assay:GO:0005768 endosome
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0031083 BLOC-1
                     complex [PMID:23547030]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007032
                     endosome organization [PMID:23547030]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032880
                     regulation of protein localization [PMID:23547030]"
                     /note="Subunit of the BLOC-1 complex involved in endosomal
                     maturation; interacts with Msb3p; green fluorescent
                     protein (GFP)-fusion protein localizes to the endosome"
                     /codon_start=1
                     /product="Bli1p"
                     /protein_id="DAA09096.1"
                     /db_xref="SGD:S000001544"
                     /translation="MGEQNKLYYDVEKLVNSLQESFDLDCAQSVSLFTSKSRSNEAWL
                     EELENKFKLKDDVELDDVENLRAEIDMKLNMLEDKVSYYERLYKELEEFQNEIKIKTV
                     VNNRRQSRTPK"
     gene            complement(326408..327487)
                     /gene="FBA1"
                     /locus_tag="YKL060C"
                     /gene_synonym="LOT1"
     mRNA            complement(326408..327487)
                     /gene="FBA1"
                     /locus_tag="YKL060C"
                     /gene_synonym="LOT1"
                     /product="fructose-bisphosphate aldolase FBA1"
     CDS             complement(326408..327487)
                     /gene="FBA1"
                     /locus_tag="YKL060C"
                     /gene_synonym="LOT1"
                     /EC_number="4.1.2.13"
                     /experiment="EXISTENCE:direct assay:GO:0004332
                     fructose-bisphosphate aldolase activity [PMID:2647491]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:11914276]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16806052|PMID:16962558|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:16806052]"
                     /experiment="EXISTENCE:direct assay:GO:1904408 melatonin
                     binding [PMID:31708896]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004332
                     fructose-bisphosphate aldolase activity [PMID:2647491]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006094
                     gluconeogenesis [PMID:6384192]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006096
                     glycolytic process [PMID:6384192]"
                     /note="Fructose 1,6-bisphosphate aldolase; required for
                     glycolysis and gluconeogenesis; catalyzes conversion of
                     fructose 1,6 bisphosphate to glyceraldehyde-3-P and
                     dihydroxyacetone-P; locates to mitochondrial outer surface
                     upon oxidative stress; N-terminally propionylated in vivo"
                     /codon_start=1
                     /product="fructose-bisphosphate aldolase FBA1"
                     /protein_id="DAA09097.1"
                     /db_xref="SGD:S000001543"
                     /translation="MGVEQILKRKTGVIVGEDVHNLFTYAKEHKFAIPAINVTSSSTA
                     VAALEAARDSKSPIILQTSNGGAAYFAGKGISNEGQNASIKGAIAAAHYIRSIAPAYG
                     IPVVLHSDHCAKKLLPWFDGMLEADEAYFKEHGEPLFSSHMLDLSEETDEENISTCVK
                     YFKRMAAMDQWLEMEIGITGGEEDGVNNENADKEDLYTKPEQVYNVYKALHPISPNFS
                     IAAAFGNCHGLYAGDIALRPEILAEHQKYTREQVGCKEEKPLFLVFHGGSGSTVQEFH
                     TGIDNGVVKVNLDTDCQYAYLTGIRDYVLNKKDYIMSPVGNPEGPEKPNKKFFDPRVW
                     VREGEKTMGAKITKSLETFRTTNTL"
     gene            complement(328118..329443)
                     /gene="MPE1"
                     /locus_tag="YKL059C"
     mRNA            complement(328118..329443)
                     /gene="MPE1"
                     /locus_tag="YKL059C"
                     /product="cleavage polyadenylation factor subunit MPE1"
     CDS             complement(328118..329443)
                     /gene="MPE1"
                     /locus_tag="YKL059C"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:22932476]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:22932476]"
                     /experiment="EXISTENCE:direct assay:GO:0005847 mRNA
                     cleavage and polyadenylation specificity factor complex
                     [PMID:12819204]"
                     /experiment="EXISTENCE:direct assay:GO:0006378 mRNA
                     polyadenylation [PMID:11713271]"
                     /experiment="EXISTENCE:direct assay:GO:0036002 pre-mRNA
                     binding [PMID:25135474]"
                     /experiment="EXISTENCE:genetic interaction:GO:0016567
                     protein ubiquitination [PMID:25135474]"
                     /experiment="EXISTENCE:genetic interaction:GO:0098789
                     pre-mRNA cleavage required for polyadenylation
                     [PMID:11713271]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000209 protein
                     polyubiquitination [PMID:32009536]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006378 mRNA
                     polyadenylation [PMID:11713271]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016567 protein
                     ubiquitination [PMID:25135474]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0036002
                     pre-mRNA binding [PMID:25135474]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0061630
                     ubiquitin protein ligase activity [PMID:32009536]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0098789
                     pre-mRNA cleavage required for polyadenylation
                     [PMID:11713271]"
                     /note="Subunit of CPF cleavage and polyadenylation factor
                     and E3 Ub-ligase; involved in 3' end formation of mRNA via
                     cleavage and polyadenylation of pre-mRNA; binds pre-mRNA
                     via the zinc knuckle and RING finger; E3 ubiquitin ligase
                     involved in polyubiquitination of the endonuclease Ysh1p;
                     contains a ubiquitin-like (UBL) domain, a RNA-binding zinc
                     knuckle motif and a RING finger domain; possible role in
                     ubiquitination of Pap1p; relocalizes to the cytosol in
                     response to hypoxia; homolog of human RBBP6"
                     /codon_start=1
                     /product="cleavage polyadenylation factor subunit MPE1"
                     /protein_id="DAA09098.1"
                     /db_xref="SGD:S000001542"
                     /translation="MSSTIFYRFKSQRNTSRILFDGTGLTVFDLKREIIQENKLGDGT
                     DFQLKIYNPDTEEEYDDDAFVIPRSTSVIVKRSPAIKSFSVHSRLKGNVGAAALGNAT
                     RYVTGRPRVLQKRQHTATTTANVSGTTEEERIASMFATQENQWEQTQEEMSAATPVFF
                     KSQTNKNSAQENEGPPPPGYMCYRCGGRDHWIKNCPTNSDPNFEGKRIRRTTGIPKKF
                     LKSIEIDPETMTPEEMAQRKIMITDEGKFVVQVEDKQSWEDYQRKRENRQIDGDETIW
                     RKGHFKDLPDDLKCPLTGGLLRQPVKTSKCCNIDFSKEALENALVESDFVCPNCETRD
                     ILLDSLVPDQDKEKEVETFLKKQEELHGSSKDGNQPETKKMKLMDPTGTAGLNNNTSL
                     PTSVNNGGTPVPPVPLPFGIPPFPMFPMPFMPPTATITNPHQADASPKK"
     rep_origin      329682..329930
                     /note="ARS1109; Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118403"
     gene            330166..330534
                     /gene="TOA2"
                     /locus_tag="YKL058W"
     mRNA            330166..330534
                     /gene="TOA2"
                     /locus_tag="YKL058W"
                     /product="transcription initiation factor IIA subunit
                     gamma"
     CDS             330166..330534
                     /gene="TOA2"
                     /locus_tag="YKL058W"
                     /experiment="EXISTENCE:direct assay:GO:0005672
                     transcription factor TFIIA complex [PMID:7862117]"
                     /experiment="EXISTENCE:direct assay:GO:0006367
                     transcription initiation from RNA polymerase II promoter
                     [PMID:7862117]"
                     /experiment="EXISTENCE:direct assay:GO:0017025 TBP-class
                     protein binding [PMID:7604282]"
                     /experiment="EXISTENCE:direct assay:GO:0051123 RNA
                     polymerase II preinitiation complex assembly
                     [PMID:15132995]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051123 RNA
                     polymerase II preinitiation complex assembly
                     [PMID:15132995]"
                     /note="TFIIA small subunit; involved in transcriptional
                     activation, acts as antirepressor or as coactivator;
                     required, along with Toa1p, for ribosomal protein gene
                     transcription in vivo; homologous to smallest subunit of
                     human and Drosophila TFIIA; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="transcription initiation factor IIA subunit
                     gamma"
                     /protein_id="DAA09099.1"
                     /db_xref="SGD:S000001541"
                     /translation="MAVPGYYELYRRSTIGNSLVDALDTLISDGRIEASLAMRVLETF
                     DKVVAETLKDNTQSKLTVKGNLDTYGFCDDVWTFIVKNCQVTVEDSHRDASQNGSGDS
                     QSVISVDKLRIVACNSKKSE"
     gene            complement(330856..333969)
                     /gene="NUP120"
                     /locus_tag="YKL057C"
                     /gene_synonym="RAT2"
     mRNA            complement(330856..333969)
                     /gene="NUP120"
                     /locus_tag="YKL057C"
                     /gene_synonym="RAT2"
                     /product="Nup120p"
     CDS             complement(330856..333969)
                     /gene="NUP120"
                     /locus_tag="YKL057C"
                     /gene_synonym="RAT2"
                     /experiment="EXISTENCE:direct assay:GO:0005643 nuclear
                     pore [PMID:10684247]"
                     /experiment="EXISTENCE:direct assay:GO:0031080 nuclear
                     pore outer ring [PMID:11823431]"
                     /experiment="EXISTENCE:direct assay:GO:0045893 positive
                     regulation of transcription, DNA-templated
                     [PMID:15817685]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006302
                     double-strand break repair [PMID:15725626]"
                     /experiment="EXISTENCE:genetic interaction:GO:0045893
                     positive regulation of transcription, DNA-templated
                     [PMID:15817685]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000055
                     ribosomal large subunit export from nucleus
                     [PMID:11071906]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000122
                     negative regulation of transcription by RNA polymerase II
                     [PMID:22110603]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000973
                     posttranscriptional tethering of RNA polymerase II gene
                     DNA at nuclear periphery [PMID:20932479]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006302
                     double-strand break repair [PMID:16418532|PMID:17538013]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006406 mRNA
                     export from nucleus
                     [PMID:8557736|PMID:8557737|PMID:8565072]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006606 protein
                     import into nucleus [PMID:12730220]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006611 protein
                     export from nucleus [PMID:8557736]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0017056
                     structural constituent of nuclear pore [PMID:22331846]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031509
                     subtelomeric heterochromatin assembly [PMID:16418532]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031990 mRNA
                     export from nucleus in response to heat stress
                     [PMID:18258809]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0034398
                     telomere tethering at nuclear periphery [PMID:16418532]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045944
                     positive regulation of transcription by RNA polymerase II
                     [PMID:22110603]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051664 nuclear
                     pore localization
                     [PMID:22331846|PMID:8557736|PMID:8557737|PMID:8565072|PMID
                     :9725905]"
                     /note="Subunit of the Nup84p subcomplex of the nuclear
                     pore complex (NPC); contributes to nucleocytoplasmic
                     transport and NPC biogenesis and is involved in
                     establishment of a normal nucleocytoplasmic concentration
                     gradient of the GTPase Gsp1p; also plays roles in several
                     processes that may require localization of genes or
                     chromosomes at the nuclear periphery, including
                     double-strand break repair, transcription and chromatin
                     silencing; homologous to human NUP160"
                     /codon_start=1
                     /product="Nup120p"
                     /protein_id="DAA09100.1"
                     /db_xref="SGD:S000001540"
                     /translation="MACLSRIDANLLQYYEKPEPNNTVDLYVSNNSNNNGLKEGDKSI
                     STPVPQPYGSEYSNCLLLSNSEYICYHFSSRSTLLTFYPLSDAYHGKTINIHLPNASM
                     NQRYTLTIQEVEQQLLVNVILKDGSFLTLQLPLSFLFSSANTLNGEWFHLQNPYDFTV
                     RVPHFLFYVSPQFSVVFLEDGGLLGLKKVDGVHYEPLLFNDNSYLKSLTRFFSRSSKS
                     DYDSVISCKLFHERYLIVLTQNCHLKIWDLTSFTLIQDYDMVSQSDSDPSHFRKVEAV
                     GEYLSLYNNTLVTLLPLENGLFQMGTLLVDSSGILTYTFQNNIPTNLSASAIWSIVDL
                     VLTRPLELNVEASYLNLIVLWKSGTASKLQILNVNDESFKNYEWIESVNKSLVDLQSE
                     HDLDIVTKTGDVERGFCNLKSRYGTQIFERAQQILSENKIIMAHNEDEEYLANLETIL
                     RDVKTAFNEASSITLYGDEIILVNCFQPYNHSLYKLNTTVENWFYNMHSETDGSELFK
                     YLRTLNGFASTLSNDVLRSISKKFLDIITGELPDSMTTVEKFTDIFKNCLENQFEITN
                     LKILFDELNSFDIPVVLNDLINNQMKPGIFWKKDFISAIKFDGFTSIISLESLHQLLS
                     IHYRITLQVLLTFVLFDLDTEIFGQHISTLLDLHYKQFLLLNLYRQDKCLLAEVLLKD
                     SSEFSFGVKFFNYGQLIAYIDSLNSNVYNASITENSFFMTFFRSYIIENTSHKNIRFF
                     LENVECPFYLRHNEVQEFMFAMTLFSCGNFDQSYEIFQLHDYPEAINDKLPTFLEDLK
                     SENYHGDSIWKDLLCTFTVPYRHSAFYYQLSLLFDRNNSQEFALKCISKSAEYSLKEI
                     QIEELQDFKEKQHIHYLNLLIHFRMFEEVLDVLRLGHECLSDTVRTNFLQLLLQEDIY
                     SRDFFSTLLRLCNAHSDNGELYLRTVDIKIVDSILSQNLRSGDWECFKKLYCFRMLNK
                     SERAAAEVLYQYILMQADLDVIRKRKCYLMVINVLSSFDSAYDQWILNGSKVVTLTDL
                     RDELRGL"
     gene            complement(334412..334915)
                     /gene="TMA19"
                     /locus_tag="YKL056C"
                     /gene_synonym="MMI1"
     mRNA            complement(334412..334915)
                     /gene="TMA19"
                     /locus_tag="YKL056C"
                     /gene_synonym="MMI1"
                     /product="Tma19p"
     CDS             complement(334412..334915)
                     /gene="TMA19"
                     /locus_tag="YKL056C"
                     /gene_synonym="MMI1"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16806052]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:16806052]"
                     /experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
                     stress granule [PMID:26777405]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0002181
                     cytoplasmic translation [PMID:16702403]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0010507
                     negative regulation of autophagy [PMID:31936125]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0034599
                     cellular response to oxidative stress [PMID:16806052]"
                     /note="Protein that associates with ribosomes; homolog of
                     translationally controlled tumor protein; green
                     fluorescent protein (GFP)-fusion protein localizes to the
                     cytoplasm and relocates to the mitochondrial outer surface
                     upon oxidative stress; homolog of human TPT1"
                     /codon_start=1
                     /product="Tma19p"
                     /protein_id="DAA09101.1"
                     /db_xref="SGD:S000001539"
                     /translation="MIIYKDIFSNDELLSDAYDAKLVDDVIYEADCAMVNVGGDNIDI
                     GANPSAEGGDDDVEEGAEMVNNVVHSFRLQQTAFDKKSFLTYIKGYMKAVKAKLQETN
                     PEEVPKFEKGAQTYVKKVIGSFKDWEFFTGESMDPDAMVVMLNYREDGTTPFVAIWKH
                     GIVEEKI"
     gene            complement(335321..336157)
                     /gene="OAR1"
                     /locus_tag="YKL055C"
     mRNA            complement(335321..336157)
                     /gene="OAR1"
                     /locus_tag="YKL055C"
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase
                     (NADPH)"
     CDS             complement(335321..336157)
                     /gene="OAR1"
                     /locus_tag="YKL055C"
                     /EC_number="1.1.1.100"
                     /experiment="EXISTENCE:direct assay:GO:0004316
                     3-oxoacyl-[acyl-carrier-protein] reductase (NADPH)
                     activity [PMID:19571038]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:24769239]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004316
                     3-oxoacyl-[acyl-carrier-protein] reductase (NADPH)
                     activity [PMID:9388293]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005739
                     mitochondrion [PMID:9388293]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006631 fatty
                     acid metabolic process [PMID:9388293]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0009060 aerobic
                     respiration [PMID:9388293]"
                     /note="Mitochondrial 3-oxoacyl-[acyl-carrier-protein]
                     reductase; may comprise a type II mitochondrial fatty acid
                     synthase along with Mct1p; human homolog CBR4 complements
                     yeast null mutant"
                     /codon_start=1
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase
                     (NADPH)"
                     /protein_id="DAA09102.1"
                     /db_xref="SGD:S000001538"
                     /translation="MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERT
                     AIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPC
                     NKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMM
                     KSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEP
                     RNIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTAL
                     ET"
     gene            complement(336537..338753)
                     /gene="DEF1"
                     /locus_tag="YKL054C"
                     /gene_synonym="VID31"
     mRNA            complement(336537..338753)
                     /gene="DEF1"
                     /locus_tag="YKL054C"
                     /gene_synonym="VID31"
                     /product="DNA damage-responsive RNA polymerase-degradation
                     factor DEF1"
     CDS             complement(336537..338753)
                     /gene="DEF1"
                     /locus_tag="YKL054C"
                     /gene_synonym="VID31"
                     /experiment="EXISTENCE:direct assay:GO:0006511
                     ubiquitin-dependent protein catabolic process
                     [PMID:11859374]"
                     /experiment="EXISTENCE:direct assay:GO:0062058
                     transcription factor TFIIH holo complex binding
                     [PMID:29180430]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006283
                     transcription-coupled nucleotide-excision repair
                     [PMID:17537816]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000723
                     telomere maintenance [PMID:15863512]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005634 nucleus
                     [PMID:11859374]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006511
                     ubiquitin-dependent protein catabolic process
                     [PMID:11859374]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006974
                     cellular response to DNA damage stimulus [PMID:11859374]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016567 protein
                     ubiquitination [PMID:24465179]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0060261
                     positive regulation of transcription initiation from RNA
                     polymerase II promoter [PMID:29180430]"
                     /note="RNAPII degradation factor; forms a complex with
                     Rad26p in chromatin, enables ubiquitination and
                     proteolysis of RNAPII present in an elongation complex;
                     interacts with general transcription factor TFIIH; mutant
                     is deficient in Zip1p loading onto chromosomes during
                     meiosis"
                     /codon_start=1
                     /product="DNA damage-responsive RNA polymerase-degradation
                     factor DEF1"
                     /protein_id="DAA09103.1"
                     /db_xref="SGD:S000001537"
                     /translation="MSTQFRKSNHNSHSSKKLNPALKSKIDTLTELFPDWTSDDLIDI
                     VQEYDDLETIIDKITSGAVTRWDEVKKPAKKEKYEKKEQQHSYVPQQHLPNPEDDITY
                     KSSNNSNSFTSTKHNSSNNYTQARNKKKVQTPRAHTTGKHVNLDKGKHVPSKPVSNTT
                     SWAAAVSVDTKHDVPQDSNDNNNEELEAQGQQAQEKNQEKEQEEQQQQEGHNNKEEHK
                     QIEQPSLSSKKTTSRTSASQPKKMSWAAIATPKPKAVKKTESPLENVAELKKEISDIK
                     KDDQKSEASEEKVNEQETSAQEQEEETAEPSEENEDRVPEVDGEEVQEEAEKKEQVKE
                     EEQTAEELEQEQDNVAAPEEEVTVVEEKVEISAVISEPPEDQANTVPQPQQQSQQPQQ
                     PQQPQQPQQPQQPQQQQQPQQPQQPQQQLQQQQQQQQQPVQAQAQAQEEQLSQNYYTQ
                     QQQQQYAQQQHQLQQQYLSQQQQYAQQQQQHPQPQSQQPQSQQSPQSQKQGNNVAAQQ
                     YYMYQNQFPGYSYPGMFDSQGYAYGQQYQQLAQNNAQTSGNANQYNFQQGYGQAGANT
                     AAANLTSAAAAAAASPATAHAQPQQQQPYGGSFMPYYAHFYQQSFPYGQPQYGVAGQY
                     PYQLPKNNYNYYQTQNGQEQQSPNQGVAQHSEDSQQKQSQQQQQQQPQGQPQPEVQMQ
                     NGQPVNPQQQMQFQQYYQFQQQQQQAAAAAAAAAQQGVPYGYNGYDYNSKNSRGFY"
     gene            complement(339182..339442)
                     /gene="MDM35"
                     /locus_tag="YKL053C-A"
     mRNA            complement(339182..339442)
                     /gene="MDM35"
                     /locus_tag="YKL053C-A"
                     /product="Mdm35p"
     CDS             complement(339182..339442)
                     /gene="MDM35"
                     /locus_tag="YKL053C-A"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005758
                     mitochondrial intermembrane space [PMID:17095012]"
                     /experiment="EXISTENCE:direct assay:GO:0015914
                     phospholipid transport [PMID:27354379]"
                     /experiment="EXISTENCE:direct assay:GO:0045332
                     phospholipid translocation [PMID:26235513]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007005
                     mitochondrion organization [PMID:11907266]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0033108
                     mitochondrial respiratory chain complex assembly
                     [PMID:19703468]"
                     /experiment="EXISTENCE:physical interaction:GO:0005515
                     protein binding [PMID:26235513]"
                     /note="Mitochondrial intermembrane space protein; forms
                     complex with Ups2p that transfers phosphatidylserine from
                     outer membrane to inner membrane for
                     phosphatidylethanolamine synthesis; mutation affects
                     mitochondrial distribution and morphology; contains twin
                     cysteine-x9-cysteine motifs; protein abundance increases
                     in response to DNA replication stress"
                     /codon_start=1
                     /product="Mdm35p"
                     /protein_id="DAA09104.1"
                     /db_xref="SGD:S000007243"
                     /translation="MGNIMSASFAPECTDLKTKYDSCFNEWYSEKFLKGKSVENECSK
                     QWYAYTTCVNAALVKQGIKPALDEAREEAPFENGGKLKEVDK"
     gene            complement(339668..340546)
                     /gene="ASK1"
                     /locus_tag="YKL052C"
     mRNA            complement(339668..340546)
                     /gene="ASK1"
                     /locus_tag="YKL052C"
                     /product="Ask1p"
     CDS             complement(339668..340546)
                     /gene="ASK1"
                     /locus_tag="YKL052C"
                     /experiment="EXISTENCE:direct assay:GO:0008017 microtubule
                     binding [PMID:15664196|PMID:16777964]"
                     /experiment="EXISTENCE:direct assay:GO:0031116 positive
                     regulation of microtubule polymerization [PMID:15664196]"
                     /experiment="EXISTENCE:direct assay:GO:0042729 DASH
                     complex [PMID:15640796|PMID:15664196]"
                     /experiment="EXISTENCE:direct assay:GO:0051010 microtubule
                     plus-end binding [PMID:17620411|PMID:20479465]"
                     /experiment="EXISTENCE:direct assay:GO:0051987 positive
                     regulation of attachment of spindle microtubules to
                     kinetochore [PMID:20479465|PMID:20479468]"
                     /note="Essential subunit of the Dam1 complex (aka DASH
                     complex); couples kinetochores to the force produced by MT
                     depolymerization thereby aiding in chromosome segregation;
                     phosphorylated during the cell cycle by cyclin-dependent
                     kinases; sumoylated in an Mms21p-dependent manner; protein
                     abundance increases in response to DNA replication stress"
                     /codon_start=1
                     /product="Ask1p"
                     /protein_id="DAA09105.1"
                     /db_xref="SGD:S000001535"
                     /translation="MDSASKEETLEKLDQEITVNLQKIDSNLSFCFHKITQDIIPHVA
                     TYSEICERIMDSTEWLGTMFQETGLVNLQANAAAPVGNAPVKSLVSNNVGIFPTSAEE
                     ASRQSQTDNGPNEADSAVHVNRDVHSMFNNDSIDDFHTANITSTGQILKLPDSSDEDT
                     GSEAVPSREQTDLTGEGHGGADDEQDESTIQRQSRKRKISLLLQQQYGSSSSMVPSPI
                     VPNKMRKQLAHEEHINNDGDNDDENSNNIESSPLKQGHHHPKGQADDNNEGPDEEEST
                     KEVPKPGTIIHFSTNR"
     gene            341312..342373
                     /gene="SFK1"
                     /locus_tag="YKL051W"
     mRNA            341312..342373
                     /gene="SFK1"
                     /locus_tag="YKL051W"
                     /product="Sfk1p"
     CDS             341312..342373
                     /gene="SFK1"
                     /locus_tag="YKL051W"
                     /experiment="EXISTENCE:direct assay:GO:0005886 plasma
                     membrane [PMID:12015967]"
                     /experiment="EXISTENCE:direct assay:GO:0071944 cell
                     periphery [PMID:26928762]"
                     /experiment="EXISTENCE:genetic interaction:GO:0007033
                     vacuole organization [PMID:12015967]"
                     /experiment="EXISTENCE:genetic interaction:GO:0030036
                     actin cytoskeleton organization [PMID:12015967]"
                     /experiment="EXISTENCE:genetic interaction:GO:0048017
                     inositol lipid-mediated signaling [PMID:12015967]"
                     /experiment="EXISTENCE:genetic interaction:GO:0061093
                     negative regulation of phospholipid translocation
                     [PMID:29540528]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005886 plasma
                     membrane [PMID:12015967]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0061093
                     negative regulation of phospholipid translocation
                     [PMID:29540528]"
                     /note="Protein that regulates phospholipid asymmetry at
                     plasma membrane; may act to generate normal levels of
                     PI4P; may act together with or upstream of Stt4p; at least
                     partially mediates proper localization of Stt4p to the
                     plasma membrane"
                     /codon_start=1
                     /product="Sfk1p"
                     /protein_id="DAA09106.1"
                     /db_xref="SGD:S000001534"
                     /translation="MIQFKSPGNWLFIVPWIAFIPWYGMLIAMLICWASQGHPIYWFM
                     HSEQFPVYISDIGATNLRPLFISCAGWQGLGYVITVALEFFQRSGYLPFQLKKKDPSI
                     SDSTSYAEKLHSGKYLMPPYYTKDERNLIFAAFVLGSIGELALLFSSIFSTALYHRVH
                     IAMVSVFVVFMFLSTCCLIAEYFLMGRHYASVHPLASPHFNPQSSEKSFNQDYNTVDE
                     LPWYKWKGHVWNKFTISATLKVIWLTLAVVWAICFGAINDRSKSACFEWLLAFWFGII
                     FMILSADFYLGGRYRQSRYFNHVESFSGYYKYDKALGLYHSEDVLPSDDNAGVIATET
                     ASSNIYNNSSSNESIQVVV"
     gene            complement(342852..345620)
                     /locus_tag="YKL050C"
     mRNA            complement(342852..345620)
                     /locus_tag="YKL050C"
                     /product="hypothetical protein"
     CDS             complement(342852..345620)
                     /locus_tag="YKL050C"
                     /note="hypothetical protein; the YKL050W protein is a
                     target of the SCFCdc4 ubiquitin ligase complex and YKL050W
                     transcription is regulated by Azf1p; YKL050C has a
                     paralog, EIS1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="DAA09107.1"
                     /db_xref="SGD:S000001533"
                     /translation="MSLISALQTTDVESVQTSPEQITERKAVRVSTLQESLHSSEMHR
                     AAPETPRSISNSVHKLKTIYSTYQQSGQPLSKEAIFRAKQKYGILNTPANYKTLGLGD
                     SKSESVDLAARLASKRTKVSPDDCVETAIEQKARGEAFKVTFSKIPLTPPEDVPITVN
                     LGLKGRRDFLTRLAAQKALAFSPSLDNSMKGTSDSSSVKKKRFSGAPIGNEFDANLVN
                     PQHPAGFKSLDLSKVLDGAERRAISRVNDRLYPQKVNFKNGLQSSDQSGVSKANKEVF
                     KKGTLEKLEHSAEQFLESHAGNERQRLSDQQYMCAKGAADAVKDLDPKTLEDPDFAAR
                     EAQKKLYIKQVASPVVLNEAQKLANRKLQDIDSRDTYMLLFGNQAYNKLAVNIALQHY
                     SVKQEEKKKIYLGGGLWMTPEEVNAVAKKLISPVVNEIDERASRQRDVDKDIERRSRV
                     LDQEYEDGNSMERAKEQNDGQLLLAMASKQQQEKEAKKAEEGQRYDQFVQKMNIKLQQ
                     KEKELENARENRENLRNELQERLSKNLSGENDELNDWNDACERDLKNSSIEHYYAVRS
                     HFDNLGNSERGYDELLEERSKIQVEIERLVASIAEHKTAIHGFGETADAGGAIPAVQK
                     QKIPTRKDLLDATVNDPLVISAEMAKEEAEMATEECMLKELQVDEMIIIRNIMLRECE
                     KKLEEEKETAKRSRRGTEESKNNSNFSRDVIMSTPDNNEKVTPIGKSASPKDVVKSRF
                     LSTYNTGKDIDSSASARSITGVSGVLDDGPKTPTSNKENELIDDEVKSYKVHQAVDGT
                     GEDSIANKRDKSSRPAANSGGSITIEQFLFNKNADKQGLSKTESVTMKREPVVDQMDS
                     KKGHDFTHCNDNGRRSFSGFSQGSIENDYSNEVTDDQDDQEGSEIRVRDSNDSNTSPK
                     ESFFKEVI"
     gene            complement(346075..346764)
                     /gene="CSE4"
                     /locus_tag="YKL049C"
                     /gene_synonym="CSL2"
     mRNA            complement(346075..346764)
                     /gene="CSE4"
                     /locus_tag="YKL049C"
                     /gene_synonym="CSL2"
                     /product="centromeric DNA-binding histone H3-like protein
                     CSE4"
     CDS             complement(346075..346764)
                     /gene="CSE4"
                     /locus_tag="YKL049C"
                     /gene_synonym="CSL2"
                     /experiment="EXISTENCE:direct assay:GO:0000776 kinetochore
                     [PMID:22365852]"
                     /experiment="EXISTENCE:direct assay:GO:0000779 condensed
                     chromosome, centromeric region
                     [PMID:16207811|PMID:23623551]"
                     /experiment="EXISTENCE:direct assay:GO:0005729
                     2-micrometer circle DNA [PMID:16966420]"
                     /experiment="EXISTENCE:direct assay:GO:0019237 centromeric
                     DNA binding [PMID:11063678|PMID:23623551]"
                     /experiment="EXISTENCE:direct assay:GO:0043505 CENP-A
                     containing nucleosome [PMID:11063678|PMID:19782029]"
                     /experiment="EXISTENCE:direct assay:GO:0043565
                     sequence-specific DNA binding [PMID:16966420]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000776
                     kinetochore [PMID:10958698]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000779
                     condensed chromosome, centromeric region [PMID:11063678]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000070 mitotic
                     sister chromatid segregation [PMID:7698647]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030543
                     2-micrometer plasmid partitioning [PMID:16966420]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0051382
                     kinetochore assembly [PMID:16207811]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0061644 protein
                     localization to CENP-A containing chromatin
                     [PMID:28980861]"
                     /note="Centromeric histone H3-like protein; associates
                     with promoters, accessible chromatin, and RNAPII-bound
                     regions; phosphorylated Cse4p associates with centromeres;
                     required for kinetochore function; Ipl1p-dependent
                     phosphorylation destabilizes defective kinetochores
                     promoting bi-orientation; increases association of Sgo1p
                     with centromeric chromatin; proteolysis regulated by
                     multiple E3 ligases, resulting in faithful chromosome
                     segregation; CSE4 complements mutations in the human
                     homolog CENPA"
                     /codon_start=1
                     /product="centromeric DNA-binding histone H3-like protein
                     CSE4"
                     /protein_id="DAA09108.1"
                     /db_xref="SGD:S000001532"
                     /translation="MSSKQQWVSSAIQSDSSGRSLSNVNRLAGDQQSINDRALSLLQR
                     TRATKNLFPRREERRRYESSKSDLDIETDYEDQAGNLEIETENEEEAEMETEVPAPVR
                     THSYALDRYVRQKRREKQRKQSLKRVEKKYTPSELALYEIRKYQRSTDLLISKIPFAR
                     LVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDM
                     QLARRIRGQFI"
     gene            complement(347214..349136)
                     /gene="ELM1"
                     /locus_tag="YKL048C"
                     /gene_synonym="LDB9"
     mRNA            complement(347214..349136)
                     /gene="ELM1"
                     /locus_tag="YKL048C"
                     /gene_synonym="LDB9"
                     /product="serine/threonine protein kinase ELM1"
     CDS             complement(347214..349136)
                     /gene="ELM1"
                     /locus_tag="YKL048C"
                     /gene_synonym="LDB9"
                     /EC_number="2.7.11.1"
                     /experiment="EXISTENCE:direct assay:GO:0000144 cellular
                     bud neck septin ring [PMID:27053666]"
                     /experiment="EXISTENCE:direct assay:GO:0004672 protein
                     kinase activity [PMID:16319894]"
                     /experiment="EXISTENCE:direct assay:GO:0004674 protein
                     serine/threonine kinase activity
                     [PMID:12847291|PMID:16201971|PMID:9180279]"
                     /experiment="EXISTENCE:direct assay:GO:0005935 cellular
                     bud neck [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0006468 protein
                     phosphorylation
                     [PMID:12847291|PMID:16201971|PMID:9180279|PMID:16319894]"
                     /experiment="EXISTENCE:direct assay:GO:0031954 positive
                     regulation of protein autophosphorylation [PMID:16861226]"
                     /experiment="EXISTENCE:direct assay:GO:0046777 protein
                     autophosphorylation [PMID:16861226]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006468
                     protein phosphorylation [PMID:12847291]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000144
                     cellular bud neck septin ring [PMID:27053666]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000281 mitotic
                     cytokinesis [PMID:10725226]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000902 cell
                     morphogenesis [PMID:16607009|PMID:9427410]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000921 septin
                     ring assembly [PMID:10725226]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007117 budding
                     cell bud growth [PMID:10234786]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007124
                     pseudohyphal growth [PMID:9891070]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031954
                     positive regulation of protein autophosphorylation
                     [PMID:16861226]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042149
                     cellular response to glucose starvation [PMID:15340085]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042493
                     response to drug [PMID:16751665]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0046777 protein
                     autophosphorylation [PMID:16861226]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1902935 protein
                     localization to septin ring [PMID:27053666]"
                     /note="Serine/threonine protein kinase; regulates the
                     orientation checkpoint, the morphogenesis checkpoint and
                     the metabolic switch from fermentative to oxidative
                     metabolism by phosphorylating the activation loop of
                     Kin4p, Hsl1p and Snf1p respectively; cooperates with Hsl7p
                     in recruiting Hsl1p to the septin ring, a prerequisite for
                     subsequent recruitment, phosphorylation, and degradation
                     of Swe1p; forms part of the bud neck ring; regulates
                     cytokinesis"
                     /codon_start=1
                     /product="serine/threonine protein kinase ELM1"
                     /protein_id="DAA09109.1"
                     /db_xref="SGD:S000001531"
                     /translation="MSPRQLIPTLIPEWAPLSQQSCIREDELDSPPITPTSQTSSFGS
                     SFSQQKPTYSTIIGENIHTILDEIRPYVKKITVSDQDKKTINQYTLGVSAGSGQFGYV
                     RKAYSSTLGKVVAVKIIPKKPWNAQQYSVNQVMRQIQLWKSKGKITTNMSGNEAMRLM
                     NIEKCRWEIFAASRLRNNVHIVRLIECLDSPFSESIWIVTNWCSLGELQWKRDDDEDI
                     LPQWKKIVISNCSVSTFAKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKL
                     SDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCHLGNSKRDFVTDGFK
                     LDIWSLGVTLYCLLYNELPFFGENEFETYHKIIEVSLSSKINGNTLNDLVIKRLLEKD
                     VTLRISIQDLVKVLSRDQPIDSRNHSQISSSSVNPVRNEGPVRRFFGRLLTKKGKKKT
                     SGKGKDKVLVSATSKVTPSIHIDEEPDKECFSTTVLRSSPDSSDYCSSLGEEAIQVTD
                     FLDTFCRSNESLPNLTVNNDKQNSDMKTDRSESSSHSSLKIPTPIKAMIRLKSSPKEN
                     GNRTHINCSQDKPSSPLMDRTVGKRTVNNSGARKLAHSSNILNFKAYINSEDSDIRET
                     VEDVKTYLNFADNGQI"
     gene            349463..351013
                     /gene="ANR2"
                     /locus_tag="YKL047W"
     mRNA            349463..351013
                     /gene="ANR2"
                     /locus_tag="YKL047W"
                     /product="Anr2p"
     CDS             349463..351013
                     /gene="ANR2"
                     /locus_tag="YKL047W"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005811 lipid
                     droplet [PMID:24868093]"
                     /note="hypothetical protein; may have a role in lipid
                     metabolism, based on localization to lipid droplets;
                     predicted to be palmitoylated"
                     /codon_start=1
                     /product="Anr2p"
                     /protein_id="DAA09110.1"
                     /db_xref="SGD:S000001530"
                     /translation="MNSGGEEPTIKPNVFNITQLLNSNGEKPGIACIFLSKFDMKKGN
                     IIIWSKSINGAAIDLSNIEFKSLPAGIHEQTDDVVNFVVPKELDVCQTAKTTTYDYGI
                     AYFKQNSFDIIENDNRIDRSKVQMFSLGVIIDVQNASSDSKKHFYKEIYHAYAANRYS
                     SYLESLLGQWIRQRDLDKFDIFEKFFDENNQGHMAENSVEVFEHSPKERRHLVEYLPY
                     WTRKLGPLIFPLWKASLLQSRILILVPQGESFELCNSLAYCVFLISMLPKNLIGNHVS
                     DEYIKPIFTVSTSDIPFLESFKKGNGYVATTSEEILLYKPEIYDIVVKLTSSSTIEES
                     PEKEVEILTASGEQNKATPLDLEVYEKLILGELQEDASTNATCRHHEVTEPISWLQFL
                     IDGFFLLTTAGYLVAPYHLANNFKIPRHVSGPEPNNSEIQIAENLVRYFHRRTSNLYN
                     DLKDVIQKSENIDSEQPITIAASFLTKLNLDCFSKQDHQFVKDIALKWFQRSIDISNL
                     PECLGNLC"
     gene            complement(351275..352624)
                     /gene="DCW1"
                     /locus_tag="YKL046C"
     mRNA            complement(351275..352624)
                     /gene="DCW1"
                     /locus_tag="YKL046C"
                     /product="putative mannan endo-1,6-alpha-mannosidase"
     CDS             complement(351275..352624)
                     /gene="DCW1"
                     /locus_tag="YKL046C"
                     /EC_number="3.2.1.101"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:14562095|PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005933 cellular
                     bud [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0009272 fungal-type
                     cell wall biogenesis [PMID:12421307]"
                     /experiment="EXISTENCE:direct assay:GO:0046658 anchored
                     component of plasma membrane [PMID:12421307]"
                     /experiment="EXISTENCE:genetic interaction:GO:0007117
                     budding cell bud growth [PMID:15470258]"
                     /note="Putative mannosidase; GPI-anchored membrane protein
                     required for cell wall biosynthesis in bud
                     formation;homologous to Dfg5p"
                     /codon_start=1
                     /product="putative mannan endo-1,6-alpha-mannosidase"
                     /protein_id="DAA09111.1"
                     /db_xref="SGD:S000001529"
                     /translation="MLVNKVIGLLGVLFATRFTNAVELDLDNYESLQNATSLIAYGLM
                     DYYTGNQYGKTVGMFSDPYYWWEAGGAWGCMLDYWFFMDNDTYNDEIIAAMIHQAGDD
                     NDYIPLNQSTTEGNDDQAFWGIAAMTAAERNFTNPPENEPQWLYLAQAVFNTMALRWD
                     ADSCGGGLRWQIFVWNSGYDYKNTVSNGALFHIAARLARYTGNQTYVDWAEKVYEWMV
                     GVNLISNGTYKYVYDGVSIDDNCTKVTSYQWTYNQGLLLAGSAYLYNFTGSDLWHTRT
                     KEFLNASQVFFHDGIVYEAACQGPNSCNTDQRSFKAYFARFLGVTAQLVPETRNQIMS
                     WLNTSAIAAAKSCSGGTDGHTCGLNWFNGTWDGMYGLGEQMSALEVMVNTRALDKPAP
                     YTAENGGSSVGDGAAGTQAQPTNLAPLNITKGSKAGAGIITAVIGISIVACALWLVF"
     gene            353493..355079
                     /gene="PRI2"
                     /locus_tag="YKL045W"
     mRNA            353493..355079
                     /gene="PRI2"
                     /locus_tag="YKL045W"
                     /product="DNA primase subunit PRI2"
     CDS             353493..355079
                     /gene="PRI2"
                     /locus_tag="YKL045W"
                     /experiment="EXISTENCE:curator inference:GO:0006270 DNA
                     replication initiation [PMID:3888995]"
                     /experiment="EXISTENCE:curator inference:GO:0006273
                     lagging strand elongation [PMID:3888995]"
                     /experiment="EXISTENCE:direct assay:GO:0003697
                     single-stranded DNA binding [PMID:20404922]"
                     /experiment="EXISTENCE:direct assay:GO:0003896 DNA primase
                     activity [PMID:3061469|PMID:3888995]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:15282802]"
                     /experiment="EXISTENCE:direct assay:GO:0005635 nuclear
                     envelope [PMID:15282802]"
                     /experiment="EXISTENCE:direct assay:GO:0005658 alpha DNA
                     polymerase:primase complex [PMID:22593576|PMID:3888995]"
                     /experiment="EXISTENCE:direct assay:GO:0006269 DNA
                     replication, synthesis of RNA primer [PMID:2644256]"
                     /experiment="EXISTENCE:genetic interaction:GO:0003896 DNA
                     primase activity [PMID:8436268]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0003896 DNA
                     primase activity [PMID:8436268]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006260 DNA
                     replication [PMID:2023935]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006302
                     double-strand break repair [PMID:10025407]"
                     /note="Subunit of DNA primase; DNA primase is required for
                     DNA synthesis and double-strand break repair"
                     /codon_start=1
                     /product="DNA primase subunit PRI2"
                     /protein_id="DAA09112.1"
                     /db_xref="SGD:S000001528"
                     /translation="MFRQSKRRIASRKNFSSYDDIVKSELDVGNTNAANQIILSSSSS
                     EEEKKLYARLYESKLSFYDLPPQGEITLEQFEIWAIDRLKILLEIESCLSRNKSIKEI
                     ETIIKPQFQKLLPFNTESLEDRKKDYYSHFILRLCFCRSKELREKFVRAETFLFKIRF
                     NMLTSTDQTKFVQSLDLPLLQFISNEEKAELSHQLYQTVSASLQFQLNLNEEHQRKQY
                     FQQEKFIKLPFENVIELVGNRLVFLKDGYAYLPQFQQLNLLSNEFASKLNQELIKTYQ
                     YLPRLNEDDRLLPILNHLSSGYTIADFNQQKANQFSENVDDEINAQSVWSEEISSNYP
                     LCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFN
                     KEYRYSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRS
                     MKLTQAQIISVLDSCQKGEYTIACTKVFEMTHNSASADLEIGEQTHIAHPNLYFERSR
                     QLQKKQQKLEKEKLFNNGNH"
     gene            356322..356642
                     /gene="MMO1"
                     /locus_tag="YKL044W"
     mRNA            356322..356642
                     /gene="MMO1"
                     /locus_tag="YKL044W"
                     /product="Mmo1p"
     CDS             356322..356642
                     /gene="MMO1"
                     /locus_tag="YKL044W"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:26928762]"
                     /note="hypothetical protein; SWAT-GFP, seamless-GFP and
                     mCherry fusion proteins localize to the mitochondria; mRNA
                     identified as translated by ribosome profiling data; MMO1
                     is a non-essential gene"
                     /codon_start=1
                     /product="Mmo1p"
                     /protein_id="DAA35123.1"
                     /db_xref="SGD:S000001527"
                     /translation="MGYVIMTFSSARMSERRARIIYIWMHLSAYKINFPFVQFPTFFS
                     LFRLQKKAAILIKNPSPFFLFFLFPYRKNSTARTIHQINQAVALVLLCVSHHLTYLPS
                     VPSL"
     gene            356748..357848
                     /gene="PHD1"
                     /locus_tag="YKL043W"
     mRNA            356748..357848
                     /gene="PHD1"
                     /locus_tag="YKL043W"
                     /product="Phd1p"
     CDS             356748..357848
                     /gene="PHD1"
                     /locus_tag="YKL043W"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:8114741]"
                     /experiment="EXISTENCE:direct assay:GO:0043565
                     sequence-specific DNA binding
                     [PMID:19111667|PMID:19158363]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0003700
                     DNA-binding transcription factor activity [PMID:16449570]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045944
                     positive regulation of transcription by RNA polymerase II
                     [PMID:8114741]"
                     /experiment="EXISTENCE:mutant phenotype:GO:2000222
                     positive regulation of pseudohyphal growth [PMID:8114741]"
                     /note="Transcriptional activator that enhances
                     pseudohyphal growth; physically interacts with the
                     Tup1-Cyc8 complex and recruits Tup1p to its targets;
                     regulates expression of FLO11, an adhesin required for
                     pseudohyphal filament formation; similar to StuA, an A.
                     nidulans developmental regulator; potential Cdc28p
                     substrate; PHD1 has a paralog, SOK2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Phd1p"
                     /protein_id="DAA09113.1"
                     /db_xref="SGD:S000001526"
                     /translation="MYHVPEMRLHYPLVNTQSNAAITPTRSYDNTLPSFNELSHQSTI
                     NLPFVQRETPNAYANVAQLATSPTQAKSGYYCRYYAVPFPTYPQQPQSPYQQAVLPYA
                     TIPNSNFQPSSFPVMAVMPPEVQFDGSFLNTLHPHTELPPIIQNTNDTSVARPNNLKS
                     IAAASPTVTATTRTPGVSSTSVLKPRVITTMWEDENTICYQVEANGISVVRRADNNMI
                     NGTKLLNVTKMTRGRRDGILRSEKVREVVKIGSMHLKGVWIPFERAYILAQREQILDH
                     LYPLFVKDIESIVDARKPSNKASLTPKSSPAPIKQEPSDNKHEIATEIKPKSIDALSN
                     GASTQGAGELPHLKINHIDTEAQTSRAKNELS"
     gene            358475..359566
                     /gene="SPC42"
                     /locus_tag="YKL042W"
     mRNA            358475..359566
                     /gene="SPC42"
                     /locus_tag="YKL042W"
                     /product="Spc42p"
     CDS             358475..359566
                     /gene="SPC42"
                     /locus_tag="YKL042W"
                     /experiment="EXISTENCE:direct assay:GO:0005821
                     intermediate layer of spindle pole body [PMID:9215630]"
                     /experiment="EXISTENCE:direct assay:GO:0005823 central
                     plaque of spindle pole body [PMID:9215630]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005200
                     structural constituent of cytoskeleton [PMID:9215630]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030474 spindle
                     pole body duplication [PMID:9153752]"
                     /note="Central plaque component of spindle pole body
                     (SPB); involved in SPB duplication, may facilitate
                     attachment of the SPB to the nuclear membrane"
                     /codon_start=1
                     /product="Spc42p"
                     /protein_id="DAA09114.1"
                     /db_xref="SGD:S000001525"
                     /translation="MNGSPTPKRYSSKSSRLYDDYYNIPYQYSNPTPMNRDYNDVGSR
                     INADKLVPEEYKRNTEFINKAVQQNKELNFKLREKQNEIFELKKIAETLRSKLEKYVD
                     ITKKLEDQNLNLQIKISDLEKKLSDANSTFKEMRFPKVKDPMVDDDPVSENYDQINVP
                     KHRAPDATGNPRTTNKVSNTSDQDSRLKAIERTLSVLTNYVMRSEDGNNDRMSPLPSP
                     LNTILPINNRLNFQEPKRYNPTVKVNPSDDDIMMYESAELKRVEEEIEELKRKILVRK
                     KHDLRKLSLNNQLQELQSMMDGDDNIKLDNVSKHNHATHRHSSQSSRDYSPSSDACLE
                     CSNDLYEKNRVKPENNMSETFATPTPNNR"
     gene            360143..360817
                     /gene="VPS24"
                     /locus_tag="YKL041W"
                     /gene_synonym="DID3"
                     /gene_synonym="VPL26"
     mRNA            360143..360817
                     /gene="VPS24"
                     /locus_tag="YKL041W"
                     /gene_synonym="DID3"
                     /gene_synonym="VPL26"
                     /product="ESCRT-III subunit protein VPS24"
     CDS             360143..360817
                     /gene="VPS24"
                     /locus_tag="YKL041W"
                     /gene_synonym="DID3"
                     /gene_synonym="VPL26"
                     /experiment="EXISTENCE:curator inference:GO:0043162
                     ubiquitin-dependent protein catabolic process via the
                     multivesicular body sorting pathway [PMID:15086794]"
                     /experiment="EXISTENCE:direct assay:GO:0000815 ESCRT III
                     complex [PMID:12194857]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:9606181]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:26928762]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045324 late
                     endosome to vacuole transport [PMID:9606181]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0070676
                     intralumenal vesicle formation [PMID:19234443]"
                     /experiment="EXISTENCE:mutant phenotype:GO:1904669 ATP
                     export [PMID:26585826]"
                     /note="One of four subunits of the ESCRT-III complex;
                     forms an endosomal sorting complex required for transport
                     III (ESCRT-III) subcomplex with Did4p; involved in the
                     sorting of transmembrane proteins into the multivesicular
                     body (MVB) pathway"
                     /codon_start=1
                     /product="ESCRT-III subunit protein VPS24"
                     /protein_id="DAA09115.1"
                     /db_xref="SGD:S000001524"
                     /translation="MDYIKKAIWGPDPKEQQRRIRSVLRKNGRNIEKSLRELTVLQNK
                     TQQLIKKSAKKNDVRTVRLYAKELYQINKQYDRMYTSRAQLDSVRMKIDEAIRMNTLS
                     NQMADSAGLMREVNSLVRLPQLRNTMIELEKELMKSGIISEMVDDTMESVGDVGEEMD
                     EAVDEEVNKIVEQYTNEKFKNVDQVPTVELAANEEEQEIPDEKVDEEADRMVNEMRER
                     LRALQN"
     gene            complement(361058..361828)
                     /gene="NFU1"
                     /locus_tag="YKL040C"
                     /gene_synonym="NUB1"
     mRNA            complement(361058..361828)
                     /gene="NFU1"
                     /locus_tag="YKL040C"
                     /gene_synonym="NUB1"
                     /product="Nfu1p"
     CDS             complement(361058..361828)
                     /gene="NFU1"
                     /locus_tag="YKL040C"
                     /gene_synonym="NUB1"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005759
                     mitochondrial matrix [PMID:10468587]"
                     /experiment="EXISTENCE:genetic interaction:GO:0106035
                     protein maturation by [4Fe-4S] cluster transfer
                     [PMID:27532773]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006880
                     intracellular sequestering of iron ion [PMID:10588895]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016226
                     iron-sulfur cluster assembly
                     [PMID:10468587|PMID:10588895]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0097428 protein
                     maturation by iron-sulfur cluster transfer
                     [PMID:12065597]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0106035 protein
                     maturation by [4Fe-4S] cluster transfer [PMID:27532773]"
                     /experiment="EXISTENCE:physical interaction:GO:0106035
                     protein maturation by [4Fe-4S] cluster transfer
                     [PMID:27532773]"
                     /note="Protein involved in Fe-S cluster transfer to
                     mitochondrial clients; protects [4Fe-4S] clusters from
                     damage due to oxidative stress; acts along with Bol3 at a
                     late step in the transfer of [4Fe-4S] clusters from the
                     ISA complex to client proteins; Fe-S loaded homodimer at
                     steady state; similar to NifU, a bacterial protein
                     required for Fe/S cluster maturation; ortholog of the
                     human NFU1, mutations of which are associated with
                     Multiple Mitochondria Dysfunctions Syndrome (MMDS1)"
                     /codon_start=1
                     /product="Nfu1p"
                     /protein_id="DAA09116.1"
                     /db_xref="SGD:S000001523"
                     /translation="MFKSVAKLGKSPIFYLNSQRLIHIKTLTTPNENALKFLSTDGEM
                     LQTRGSKSIVIKNTDENLINHSKLAQQIFLQCPGVESLMIGDDFLTINKDRMVHWNSI
                     KPEIIDLLTKQLAYGEDVISKEFHAVQEEEGEGGYKINMPKFELTEEDEEVSELIEEL
                     IDTRIRPAILEDGGDIDYRGWDPKTGTVYLRLQGACTSCSSSEVTLKYGIESMLKHYV
                     DEVKEVIQIMDPEQEIALKEFDKLEKKLESSKNTSHEK"
     gene            362622..364193
                     /gene="PTM1"
                     /locus_tag="YKL039W"
     mRNA            362622..364193
                     /gene="PTM1"
                     /locus_tag="YKL039W"
                     /product="Ptm1p"
     CDS             362622..364193
                     /gene="PTM1"
                     /locus_tag="YKL039W"
                     /note="hypothetical protein; copurifies with late Golgi
                     vesicles containing the v-SNARE Tlg2p; PTM1 has a paralog,
                     YHL017W, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Ptm1p"
                     /protein_id="DAA09117.1"
                     /db_xref="SGD:S000001522"
                     /translation="MRVYQFCRPFQLFTCFLCYLLVFVKANKEKISQKNYQVCAGMYS
                     KEDWKGKIDPFISFNLKKISGLSDESDPGLVVAIYDFQDFEHLGVQLPDEEMYYICDD
                     YAIDIGICEEENRDEFIVQDVVYDPYTSTNRSLANPIMTFSQNEVGLHDTRYPIKETG
                     FYCVTAFRSSTSTKFNAVVNFRNAYGQLAGTEINKLPLYGLLAVAYVVAMALYSFAFW
                     KHKHELLPLQKYLLAFFVFLTAETIFVWAYYDLKNEKGDTAGIKVYMVFLSILTAGKV
                     TFSFFLLLIIALGYGIVYPKLNKTLMRRCQMYGALTYAICIGFLIQSYLTDMEAPSPL
                     ILITLIPMALALIIFYYMIIRSMTKTVIYLKEQRQIVKLNMYKKLLYIIYASFLSVLA
                     GSIVSSFIYVGMNTIDMIEKNWRSRFFVTDFWPTLVYFIVFVTIAFLWRPTDTSYMLA
                     ASQQLPTDPENVADFDLGDLQSFDDQDDASIITGERGIDEDDLNLNFTDDEEGHDNVN
                     NHSQGHGPVSPSPTK"
     gene            364776..364876
                     /gene="SNR69"
                     /locus_tag="YNCK0013W"
     ncRNA           364776..364876
                     /ncRNA_class="snoRNA"
                     /gene="SNR69"
                     /locus_tag="YNCK0013W"
                     /product="SNR69"
                     /experiment="EXISTENCE:curator inference:GO:0005730
                     nucleolus [PMID:10024243]"
                     /experiment="EXISTENCE:curator inference:GO:0031428 box
                     C/D RNP complex [PMID:10024243]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0030562 rRNA
                     2'-O-ribose methylation guide activity [PMID:10024243]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031167 rRNA
                     methylation [PMID:10024243]"
                     /note="C/D box small nucleolar RNA (snoRNA); guides
                     2'-O-methylation of large subunit (LSU) rRNA at position
                     C2948"
                     /db_xref="SGD:S000006460"
     gene            365605..369117
                     /gene="RGT1"
                     /locus_tag="YKL038W"
     mRNA            365605..369117
                     /gene="RGT1"
                     /locus_tag="YKL038W"
                     /product="Rgt1p"
     CDS             365605..369117
                     /gene="RGT1"
                     /locus_tag="YKL038W"
                     /experiment="EXISTENCE:curator inference:GO:0005634
                     nucleus [PMID:10087931]"
                     /experiment="EXISTENCE:direct assay:GO:0000122 negative
                     regulation of transcription by RNA polymerase II
                     [PMID:12861007]"
                     /experiment="EXISTENCE:direct assay:GO:0000978 RNA
                     polymerase II cis-regulatory region sequence-specific DNA
                     binding [PMID:12239282|PMID:12861007|PMID:8887670]"
                     /experiment="EXISTENCE:direct assay:GO:0001228 DNA-binding
                     transcription activator activity, RNA polymerase
                     II-specific [PMID:8887670]"
                     /experiment="EXISTENCE:direct assay:GO:0003677 DNA binding
                     [PMID:12861007]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:12861007]"
                     /experiment="EXISTENCE:direct assay:GO:0045944 positive
                     regulation of transcription by RNA polymerase II
                     [PMID:8887670]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000122
                     negative regulation of transcription by RNA polymerase II
                     [PMID:8887670]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006006
                     glucose metabolic process [PMID:8013905]"
                     /note="Glucose-responsive transcription factor; regulates
                     expression of several glucose transporter (HXT) genes in
                     response to glucose; binds to promoters and acts both as a
                     transcriptional activator and repressor; recruits
                     Tup1p/Cyc8p to target gene promoters; RGT1 has a paralog,
                     EDS1, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Rgt1p"
                     /protein_id="DAA09118.1"
                     /db_xref="SGD:S000001521"
                     /translation="MNELNTVSTNSSDSTKNGGTSNSPDDMDSAAAASHAIKKRTKAS
                     RACDQCRKKKIKCDYKDEKGVCSNCQRNGDRCSFDRVPLKRGPSKGYTRSTSHPRTNE
                     IQDHNNSRSYNTFDNSNNTLNNNTGNSGDNGINSNTVPSTPSRSNSVLLPPLTQYIPQ
                     AGGIPPSFQNPAIQSTMPAGNIGQQQFWKVPYHEFQHQRKGSIDSLQSDISVRTLNPN
                     EQLSYNTVQQSPITNKHTNDSGNANGSVTGSGSASGSGGYWSFIRTSGLLAPTDDHNG
                     EQTRRSSSIPSLLRNTSNSLLLGGQPQLPPPQQQSQPQAHQQKLQQGQNLYSYSQFSQ
                     QQPYNPSISSFGQFAANGFHSRQGSVASEAMSPSAPAMFTSTSTNPVNVAQQTQRPQG
                     QQVPQFSSELDGNKRRQSAPVSVTLSTDRLNGNENNNGEINNNNGSNNSGSSKDTSQH
                     SQESVTTPAALEASSPGSTPQRSTKKRRKSYVSKKTKPKRDSSISITSKDSAHPMTTS
                     STIAYGQISDVDLIDTYYEFIHVGFPIIPLNKTTLTSDLLLVNTQPISNIHEVNSYVI
                     LWFRNSLELLVRVALKQKPGGKFFDNIVGVALSPSNDNNKAGFTTATARDDAEKTRRD
                     SHNEVQDTLEVQSVFIAALNECFQKIVDIHPKFRENNDQISPKIKVIYLSTFILLNYI
                     LAFVGYDNSFVLGMSVTIFNEFKLYKLLLFPEPDINDVKPPVDEEVSTGNGNTKTSEF
                     EIGSESAGHMNPSNSPNSMDENISHYSVLFKRLYVLLSVFDSLQSCAFGGPKLLNISI
                     QGSTERFFSNDLGSKWCLEQSQLRLKSVLQSLKLGELMSELTRNRISMNGNRKPGFDI
                     TNSSSLLSEYVETQPLSVAQLFCKLLIGKHNFINCLLSLYDSEAGVYSDLTLDLSSKI
                     ADSLCSLISIILQVLTLILRLNPTNSIDFNYRPPNPPANNPTVQEGPSAMGSSPVAGN
                     LSAAPPSEGNPDFYKKLLGLKQDTGTILSDLCRGIISPFAIAILHEVYNITELVKQMP
                     TSLISIMMTATTTQNTQDTKKSQDLVMKLSNSMNEVVQITSVLTMIKPFKIFEHELNK
                     PIMSLTGGLSSTTRNDVMWPKSGQGLRESSVMKTLLDERRTSGTQPTTAPVAAEEPRL
                     ENVALENFVSIGWKLLDDSELGWY"
     gene            369365..369721
                     /gene="AIM26"
                     /locus_tag="YKL037W"
     mRNA            369365..369721
                     /gene="AIM26"
                     /locus_tag="YKL037W"
                     /product="Aim26p"
     CDS             369365..369721
                     /gene="AIM26"
                     /locus_tag="YKL037W"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:19793921]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000422
                     autophagy of mitochondrion [PMID:19793921]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016236
                     macroautophagy [PMID:19793921]"
                     /note="hypothetical protein; null mutant is viable and
                     displays elevated frequency of mitochondrial genome loss;
                     null mutation confers sensitivity to tunicamycin and DTT"
                     /codon_start=1
                     /product="Aim26p"
                     /protein_id="DAA09119.1"
                     /db_xref="SGD:S000001520"
                     /translation="MQTMGGEHLLLSQLKGSFFLLLLAYFFRGRSPYYARCYRRLAVT
                     PGAITIAIAIATDSIPALAKSKVLVSVCSHTDPCTASCNLIPFPRPFSNSLTRFLFCL
                     GSARFCISFPCFGLSI"
     gene            369891..371390
                     /gene="UGP1"
                     /locus_tag="YKL035W"
     mRNA            369891..371390
                     /gene="UGP1"
                     /locus_tag="YKL035W"
                     /product="UTP glucose-1-phosphate uridylyltransferase"
     CDS             369891..371390
                     /gene="UGP1"
                     /locus_tag="YKL035W"
                     /EC_number="2.7.7.9"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005886 plasma
                     membrane [PMID:16622836]"
                     /experiment="EXISTENCE:direct assay:GO:0010494 cytoplasmic
                     stress granule [PMID:26777405]"
                     /experiment="EXISTENCE:direct assay:GO:0070569
                     uridylyltransferase activity [PMID:22580055]"
                     /experiment="EXISTENCE:genetic interaction:GO:0005978
                     glycogen biosynthetic process [PMID:9252577]"
                     /experiment="EXISTENCE:genetic interaction:GO:0005992
                     trehalose biosynthetic process [PMID:9252577]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006011
                     UDP-glucose metabolic process [PMID:9252577]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0003983
                     UTP:glucose-1-phosphate uridylyltransferase activity
                     [PMID:7588797]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0005978
                     glycogen biosynthetic process [PMID:9252577]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006011
                     UDP-glucose metabolic process [PMID:7588797|PMID:9252577]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006078
                     (1->6)-beta-D-glucan biosynthetic process [PMID:17531808]"
                     /note="UDP-glucose pyrophosphorylase (UGPase); catalyses
                     the reversible formation of UDP-Glc from glucose
                     1-phosphate and UTP, involved in a wide variety of
                     metabolic pathways, expression modulated by Pho85p through
                     Pho4p; involved in PKA-mediated oxidative stress
                     resistance and long-term survival in stationary phase;
                     UGP1 has a paralog, YHL012W, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="UTP glucose-1-phosphate uridylyltransferase"
                     /protein_id="DAA09120.1"
                     /db_xref="SGD:S000001518"
                     /translation="MSTKKHTKTHSTYAFESNTNSVAASQMRNALNKLADSSKLDDAA
                     RAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKYEIISQQPENVSNLS
                     KLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDVPLLLMNS
                     FNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSPLDAWYPPGHGD
                     LFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGAEYIMELTDKTR
                     ADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINLKAVKRLIES
                     SNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHFDGAHGVVVPRSRFLPVKTCSD
                     LLLVKSDLFRLEHGSLKLDPSRFGPNPLIKLGSHFKKVSGFNARIPHIPKIVELDHLT
                     ITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVTGNLQILEH"
     gene            371829..374105
                     /gene="TUL1"
                     /locus_tag="YKL034W"
     mRNA            371829..374105
                     /gene="TUL1"
                     /locus_tag="YKL034W"
                     /product="ubiquitin-protein ligase TUL1"
     CDS             371829..374105
                     /gene="TUL1"
                     /locus_tag="YKL034W"
                     /EC_number="2.3.2.27"
                     /experiment="EXISTENCE:direct assay:GO:0000324 fungal-type
                     vacuole [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005794 Golgi
                     apparatus [PMID:11788821]"
                     /experiment="EXISTENCE:direct assay:GO:0044695 Dsc E3
                     ubiquitin ligase complex [PMID:22681890]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004842
                     ubiquitin-protein transferase activity [PMID:11788821]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016567 protein
                     ubiquitination [PMID:11788821]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0043162
                     ubiquitin-dependent protein catabolic process via the
                     multivesicular body sorting pathway [PMID:11788821]"
                     /note="Subunit of the DSC ubiquitin ligase complex;
                     golgi-localized RING-finger ubiquitin ligase (E3) involved
                     in sorting polar transmembrane domain containing membrane
                     proteins to multivesicular bodies for delivery to the
                     vacuole; proposed involvement in the quality control of
                     misfolded TMD containing proteins; ortholog of fission
                     yeast dsc1"
                     /codon_start=1
                     /product="ubiquitin-protein ligase TUL1"
                     /protein_id="DAA09121.1"
                     /db_xref="SGD:S000001517"
                     /translation="MEIDGNTLVFIIVILFLFFSSPGGDGVSSQYEFNQLQRLKQQFR
                     TEHNTFVNMTYTDSFRNITGLKLSYQDMLNNPLQNATYPLPGKDYDRWFPNQNYMVLP
                     NDVIEAINTEVWNTSNDDASNLFPPNITSTLLGKIDLVSNNKYEKIRMPVPRFYEPAT
                     DFSEDIPPEGETYWSEWPSYGELHNVSFQHGEIAIQISHMSNLQDNNNYLRRNFINKK
                     NDRWKLLNLQIDFSDKAEKEKHSIYSKAVYDIQRGRILSISQSSKFHSLFALPHYMSF
                     QNDYNEKIFNDVKELVDEFWNFTDYTDVMTMKDVQDAYNNANFKCEYLIFLQLEPWNQ
                     YTRDQIKLIDDELNWPLGRPANLSSLPPINVVSGLLYSPDCGVRLGLHNVKGTRYELK
                     IMSIRKHLLFGIALFAAQIYLLLTQMHHTNTPSMVNKISFYCFSMINLVDGSLATLYF
                     VAASVVPELYLPLVISAFSCFILASIFEIRYLISIYASQVNEQNVGIINLLRGNTGTY
                     DENRPRPAFIPDEGSIGGSLYGRFFFMLIIFTFLILSSTSWPRQLRMVFEYILIFILN
                     SYWIPQIFRNAVKGIPSRRERARSSIGGNRSQNKMPLLWSFVIGTTIIRSLPVVYVFT
                     YSSNVFRHHKDVHFVVFLSLWLLFQISILYSQDVLGSRWFLPKHTIPDGYSYFKPLSN
                     EYISEHGGGTAEHTVDCAICMSDVPIYIEEIPETHKVDQHSYMVTPCNHVFHTSCLEN
                     WMNYKLQCPVCRSPLPPL"
     gene            374505..375215
                     /locus_tag="YKL033W-A"
     mRNA            374505..375215
                     /locus_tag="YKL033W-A"
                     /product="putative hydrolase"
     CDS             374505..375215
                     /locus_tag="YKL033W-A"
                     /experiment="EXISTENCE:direct assay:GO:0008253
                     5'-nucleotidase activity [PMID:26071590]"
                     /experiment="EXISTENCE:direct assay:GO:1990738
                     pseudouridine 5'-phosphatase activity [PMID:26071590]"
                     /note="hypothetical protein; similar to uncharacterized
                     proteins from other fungi"
                     /codon_start=1
                     /product="putative hydrolase"
                     /protein_id="DAA09122.1"
                     /db_xref="SGD:S000007242"
                     /translation="MTHPVAVKACLFDMDGLLINTEDIYTETLNETLAEFGKGPLTWD
                     VKIKLQGLPGPEAGKRVIEHYKLPITLDEYDERNVALQSLKWGTCEFLPGALNLLKYL
                     KLKNIPIALCTSSNKTKFRGKTSHLEEGFDLFDTIVTGDDPRIAKGRGKPFPDIWQLG
                     LKELNEKFHTDIKPDECIVFEDGIPGVKSAKAFGAHVIWVPHPEAHAVLGDTEALLAG
                     KGELLSSLEKLEMSKYGL"
     gene            375456..378572
                     /gene="TTI1"
                     /locus_tag="YKL033W"
     mRNA            375456..378572
                     /gene="TTI1"
                     /locus_tag="YKL033W"
                     /product="Tti1p"
     CDS             375456..378572
                     /gene="TTI1"
                     /locus_tag="YKL033W"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0070209 ASTRA
                     complex [PMID:19040720]"
                     /note="Subunit of the ASTRA complex, involved in chromatin
                     remodeling; telomere length regulator involved in the
                     stability or biogenesis of PIKKs such as TORC1; similar to
                     S. pombe Tti1p; detected in highly purified mitochondria
                     in high-throughput studies"
                     /codon_start=1
                     /product="Tti1p"
                     /protein_id="DAA09123.1"
                     /db_xref="SGD:S000001516"
                     /translation="MNSDTNAFKDIRISCVELSRIAFLPTESFDPNSLTLLACLKKVE
                     EKLSAYEDDSLSPKFADYVFVPIASLLKQPALGESQTEYVLLIIFHLLRTCWSSNGKF
                     SEQLGQQLFPLITFLVSSDKDNQKLITRSDEFKYAGCLVLHQFFKSVRSQRYHKEFFS
                     NSKPNLLPALGHSVTILLKILEQSPQNNELQFKALASLEVLFQDIISDGEMLSFILPG
                     NVSVFAKILTKPGRQIHYKVCVRTLEVLAKLLVLVYDDFSLDIKVNKLTDIRELSDTK
                     LKHEINQSFMFNGPIVLLRTDGKTHRDTSWLTATSGQINIALEAFIPKLLKRNNESID
                     EALATFVSILLTRCENSLNNCEKVLVSTLVHLERDPMSKLPSHLVKLKEVVNEDLHKL
                     SDIIRFENADRLSSLSFAITILEKNNERDTMINEVVRCLFESLNESIEPPSLINHKER
                     IIEQSSQLTTTVNFENLESTNALIALPRLSEDMSLKLKKFTYHMGSLLLERHILNDVV
                     TELISEQVDSPRTQKIVALWLSTNFIKAMEKQPKEEEVYLQFESDANYSSSMVEEVCL
                     IVLEFCNELSQDISMEIEGKGIKKSDEFAVCTVLFSIETICAVMREEFQPELIDYIYT
                     VVDALASPSEAIRYVSQSCALRIADTLYHGSIPNMILSNVDYLVESISSRLNSGMTER
                     VSQILMVICQLAGYETIENFKDVIETIFKLLDYYHGYSDLCLQFFQLFKIIILEMKKK
                     YINDDEMILKIANQHISQSTFSPWGMTDFQQVLNILDKETQVKDDITDENDVDFLKDD
                     NEPSNFQEYFDSKLREPDSDDDEEEREEEVEGSSKEYTDQWTSPIPSDSYKILLQILG
                     YGERLLTHPSKRLRVQILIVMRLIFPLLSTQHNLLIREVASTWDSIIQCVLCSDYSIV
                     QPACSCVEQMIKYSGDFVAKRFIELWQKLCQDSFILKELRIDPTVHNHEKKSISKHVK
                     FPPVTENALVSMVHMVLEGVKITEYLISEAVLEQIIYCCIQVVPVEKISSMSLIVGDI
                     VWKIRNIN"
     gene            379680..379753
                     /locus_tag="YNCK0014W"
     tRNA            379680..379753
                     /locus_tag="YNCK0014W"
                     /product="tRNA-Val"
                     /experiment="EXISTENCE:curator inference:GO:0005829
                     cytosol [PMID:9023104]"
                     /experiment="EXISTENCE:curator inference:GO:0006414
                     translational elongation [PMID:9023104]"
                     /note="Valine tRNA (tRNA-Val), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="SGD:S000006761"
     gene            complement(380065..381858)
                     /gene="IXR1"
                     /locus_tag="YKL032C"
                     /gene_synonym="ORD1"
     mRNA            complement(380065..381858)
                     /gene="IXR1"
                     /locus_tag="YKL032C"
                     /gene_synonym="ORD1"
                     /product="DNA-binding transcription repressor IXR1"
     CDS             complement(380065..381858)
                     /gene="IXR1"
                     /locus_tag="YKL032C"
                     /gene_synonym="ORD1"
                     /experiment="EXISTENCE:direct assay:GO:0000785 chromatin
                     [PMID:19807692]"
                     /experiment="EXISTENCE:direct assay:GO:0001046 core
                     promoter sequence-specific DNA binding [PMID:29449612]"
                     /experiment="EXISTENCE:direct assay:GO:0003684 damaged DNA
                     binding [PMID:8634251]"
                     /experiment="EXISTENCE:direct assay:GO:0043565
                     sequence-specific DNA binding
                     [PMID:11115121|PMID:19807692]"
                     /experiment="EXISTENCE:genetic interaction:GO:0071456
                     cellular response to hypoxia [PMID:19807692]"
                     /experiment="EXISTENCE:genetic interaction:GO:2000819
                     regulation of nucleotide-excision repair [PMID:8538651]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000122
                     negative regulation of transcription by RNA polymerase II
                     [PMID:11115121]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0071456
                     cellular response to hypoxia [PMID:19807692]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0072718
                     response to cisplatin [PMID:29449612]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0090069
                     regulation of ribosome biogenesis [PMID:29449612]"
                     /note="Transcriptional repressor that regulates hypoxic
                     genes during normoxia; involved in the aerobic repression
                     of genes such as COX5b, TIR1, and HEM13; binds DNA
                     intrastrand cross-links formed by cisplatin; HMG (high
                     mobility group box) domain containing protein which binds
                     and bends cisplatin-modified DNA, blocking excision
                     repair; IXR1 has a paralog, ABF2, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="DNA-binding transcription repressor IXR1"
                     /protein_id="DAA09124.1"
                     /db_xref="SGD:S000001515"
                     /translation="MNTGISPKQDDASNSNLLNIGQDHSLQYQGLEHNDSQYRDASHQ
                     TPHQYLNQFQAQPQQQQQQQQQQQQQQQQAPYQGHFQQSPQQQQQNVYYPLPPQSLTQ
                     PTSQSQQQQQQQQQQQYANSNSNSNNNVNVNALPQDFGYMQQTGSGQNYPTINQQQFS
                     EFYNSFLSHLTQKQTNPSVTGTGASSNNNSNNNNVSSGNNSTSSNPAQLAASQLNPAT
                     AAAAAANNAAGPASYLSQLPQVQRYYPNNMNALSSLLDPSSAGNAAGNANTATHPGLL
                     PPNLQPQLTHHQQQMQQQLQLQQQQQLQQQQQLQQQHQLQQQQQLQQQHHHLQQQQQQ
                     QQHPVVKKLSSTQSRIERRKQLKKQGPKRPSSAYFLFSMSIRNELLQQFPEAKVPELS
                     KLASARWKELTDDQKKPFYEEFRTNWEKYRVVRDAYEKTLPPKRPSGPFIQFTQEIRP
                     TVVKENPDKGLIEITKIIGERWRELDPAKKAEYTETYKKRLKEWESCYPDENDPNGNP
                     TGHSHKAMNMNLNMDTKIMENQDSIEHITANAIDSVTGSNSNSTNPNTPVSPPISLQQ
                     QPLQQQQQQQQQQQHMLLADPTTNGSIIKNE"
     gene            complement(382716..384725)
                     /gene="MAE1"
                     /locus_tag="YKL029C"
     mRNA            complement(382716..384725)
                     /gene="MAE1"
                     /locus_tag="YKL029C"
                     /product="malate dehydrogenase
                     (oxaloacetate-decarboxylating)"
     CDS             complement(382716..384725)
                     /gene="MAE1"
                     /locus_tag="YKL029C"
                     /EC_number="1.1.1.38"
                     /experiment="EXISTENCE:direct assay:GO:0004470 malic
                     enzyme activity [PMID:9603875]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion
                     [PMID:9603875|PMID:14576278|PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006090
                     pyruvate metabolic process [PMID:9603875]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006520
                     cellular amino acid metabolic process [PMID:9603875]"
                     /note="Mitochondrial malic enzyme; catalyzes the oxidative
                     decarboxylation of malate to pyruvate, which is a key
                     intermediate in sugar metabolism and a precursor for
                     synthesis of several amino acids"
                     /codon_start=1
                     /product="malate dehydrogenase
                     (oxaloacetate-decarboxylating)"
                     /protein_id="DAA09125.1"
                     /db_xref="SGD:S000001512"
                     /translation="MLRTRLSVSVAARSQLTRSLTASRTAPLRRWPIQQSRLYSSNTR
                     SHKATTTRENTFQKPYSDEEVTKTPVGSRARKIFEAPHPHATRLTVEGAIECPLESFQ
                     LLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFM
                     TSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSI
                     ECRLATYGGDKDVDYIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLP
                     VCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKKVYPSAVLHFEDFGV
                     KNARRLLEKYRYELPSFNDDIQGTGAVVMASLIAALKHTNRDLKDTRVLIYGAGSAGL
                     GIADQIVNHMVTHGVDKEEARKKIFLMDRRGLILQSYEANSTPAQHVYAKSDAEWAGI
                     NTRSLHDVVENVKPTCLVGCSTQAGAFTQDVVEEMHKHNPRPIIFPLSNPTRLHEAVP
                     ADLMKWTNNNALVATGSPFPPVDGYRISENNNCYSFPGIGLGAVLSRATTITDKMISA
                     AVDQLAELSPLREGDSRPGLLPGLDTITNTSARLATAVILQALEEGTARIEQEQVPGG
                     APGETVKVPRDFDECLQWVKAQMWEPVYRPMIKVQHDPSVHTNQL"
     gene            385758..387206
                     /gene="TFA1"
                     /locus_tag="YKL028W"
     mRNA            385758..387206
                     /gene="TFA1"
                     /locus_tag="YKL028W"
                     /product="transcription factor TFIIE subunit TFA1"
     CDS             385758..387206
                     /gene="TFA1"
                     /locus_tag="YKL028W"
                     /experiment="EXISTENCE:direct assay:GO:0000993 RNA
                     polymerase II complex binding [PMID:8702741]"
                     /experiment="EXISTENCE:direct assay:GO:0001097 TFIIH-class
                     transcription factor complex binding [PMID:8702741]"
                     /experiment="EXISTENCE:direct assay:GO:0001113
                     transcription open complex formation at RNA polymerase II
                     promoter [PMID:10973956]"
                     /experiment="EXISTENCE:direct assay:GO:0003697
                     single-stranded DNA binding [PMID:9271406]"
                     /experiment="EXISTENCE:direct assay:GO:0005673
                     transcription factor TFIIE complex
                     [PMID:1429681|PMID:7961670]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961]"
                     /experiment="EXISTENCE:direct assay:GO:0006366
                     transcription by RNA polymerase II
                     [PMID:1331084|PMID:1429681|PMID:7961670]"
                     /experiment="EXISTENCE:direct assay:GO:0097550
                     transcription preinitiation complex [PMID:22751016]"
                     /experiment="EXISTENCE:genetic interaction:GO:0001113
                     transcription open complex formation at RNA polymerase II
                     promoter [PMID:10973956]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006366
                     transcription by RNA polymerase II
                     [PMID:9188494|PMID:9271406]"
                     /experiment="EXISTENCE:physical interaction:GO:0000993 RNA
                     polymerase II complex binding [PMID:11779853]"
                     /note="TFIIE large subunit; involved in recruitment of RNA
                     polymerase II to the promoter, activation of TFIIH, and
                     promoter opening"
                     /codon_start=1
                     /product="transcription factor TFIIE subunit TFA1"
                     /protein_id="DAA09126.1"
                     /db_xref="SGD:S000001511"
                     /translation="MDRPIDDIVKNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLK
                     QLLSINKTELGPLIARLRSDRLISIHKQREYPPNSKSVERVYYYVKYPHAIDAIKWKV
                     HQVVQRLKDDLDKNSEPNGYMCPICLTKYTQLEAVQLLNFDRTEFLCSLCDEPLVEDD
                     SGKKNKEKQDKLNRLMDQIQPIIDSLKKIDDSRIEENTFEIALARLIPPQNQSHAAYT
                     YNPKKGSTMFRPGDSAPLPNLMGTALGNDSSRRAGANSQATLHINITTASDEVAQREL
                     QERQAEEKRKQNAVPEWHKQSTIGKTALGRLDNEEEFDPVVTASAMDSINPDNEPAQE
                     TSYQNNRTLTEQEMEERENEKTLNDYYAALAKKQAKLNKEEEEEEEEEEDEEEEEEEE
                     MEDVMDDNDETARENALEDEFEDVTDTAGTAKTESNTSNDVKQESINDKTEDAVNATA
                     TASGPSANAKPNDGDDDDDDDDDEMDIEFEDV"
     gene            387562..388905
                     /gene="TCD2"
                     /locus_tag="YKL027W"
     mRNA            387562..388905
                     /gene="TCD2"
                     /locus_tag="YKL027W"
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
     CDS             387562..388905
                     /gene="TCD2"
                     /locus_tag="YKL027W"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion
                     [PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005741
                     mitochondrial outer membrane [PMID:16407407]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0061503 tRNA
                     threonylcarbamoyladenosine dehydratase [PMID:23242255]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0061504 cyclic
                     threonylcarbamoyladenosine biosynthetic process
                     [PMID:23242255]"
                     /note="tRNA threonylcarbamoyladenosine dehydratase;
                     required for the ct6A tRNA base modification, where an
                     adenosine at position 37 is modified to form a cyclized
                     active ester with an oxazolone ring; localized to the
                     mitochondrial outer membrane; TCD2 has a paralog, TCD1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="DAA09127.1"
                     /db_xref="SGD:S000001510"
                     /translation="MVEKDTWKLITATALFTVAVTTITDYAWTSWQAQKQVIAQQKNK
                     NKGGQTKSDTDKYHQYDEQFIRQSLKNNVEFLGEDTIEKLSNQYVVVVGAGGVGSWVV
                     NSLVRSGCRKIRVVDFDQVSLSSLNRHSCAILNDVGTPKVECLRRHMREIAPWCEIDP
                     INELWTLQNGERLTLGNGTPDFIVDCIDNIDTKVDLLEFAYNHGIKVISSMGASAKSD
                     PTKLNVGDLATTEEDPLARVVRRKLKKRGILSGIPVVFSAEKPDPKKAKLLPLPDEEY
                     ERGKVDELSALKDFRVRILPVLGTMPSLFGLTITTWILSNISDKPLEPVEGKNRIKVY
                     DGIYQSLAGQMSRVGIPSQRIPLALKDVSYLVEEVFKGKSPISGISTRLTLTKWDPSK
                     PISLQNVVVLTKNEQKVHEDRVLKGKESLQDVYDAKVLKLVSQRFREEAYYSQFR"
     rep_origin      388970..389264
                     /note="ARS1112; Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118404"
     gene            complement(389380..389883)
                     /gene="GPX1"
                     /locus_tag="YKL026C"
     mRNA            complement(389380..389883)
                     /gene="GPX1"
                     /locus_tag="YKL026C"
                     /product="glutathione peroxidase GPX1"
     CDS             complement(389380..389883)
                     /gene="GPX1"
                     /locus_tag="YKL026C"
                     /EC_number="1.11.1.9"
                     /EC_number="1.11.1.24"
                     /experiment="EXISTENCE:direct assay:GO:0005782 peroxisomal
                     matrix [PMID:22659048]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0031315 extrinsic
                     component of mitochondrial outer membrane [PMID:22659048]"
                     /experiment="EXISTENCE:direct assay:GO:0047066
                     phospholipid-hydroperoxide glutathione peroxidase activity
                     [PMID:11445588]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004602
                     glutathione peroxidase activity [PMID:10480913]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0007031
                     peroxisome organization [PMID:22659048]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0034599
                     cellular response to oxidative stress [PMID:11445588]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0047066
                     phospholipid-hydroperoxide glutathione peroxidase activity
                     [PMID:11445588]"
                     /note="Phospholipid hydroperoxide glutathione peroxidase;
                     induced by glucose starvation that protects cells from
                     phospholipid hydroperoxides and nonphospholipid peroxides
                     during oxidative stress; glutathione peroxidase activity
                     is neuroprotective in models of Huntington's disease; GPX1
                     has a paralog, HYR1, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="glutathione peroxidase GPX1"
                     /protein_id="DAA09128.1"
                     /db_xref="SGD:S000001509"
                     /translation="MQEFYSFSPIDENGNPFPFNSLRNKVVLIVNVASHCAFTPQYKE
                     LEYLYEKYKSHGLVIVAFPCGQFGNQEFEKDKEINKFCQDKYGVTFPILHKIRCNGQK
                     QDPVYKFLKNSVSGKSGIKMIKWNFEKFVVDRNGKVVKRFSCMTRPLELCPIIEELLN
                     QPPEEQI"
     gene            complement(390240..392279)
                     /gene="PAN3"
                     /locus_tag="YKL025C"
                     /gene_synonym="ECM35"
     mRNA            complement(390240..392279)
                     /gene="PAN3"
                     /locus_tag="YKL025C"
                     /gene_synonym="ECM35"
                     /product="Pan3p"
     CDS             complement(390240..392279)
                     /gene="PAN3"
                     /locus_tag="YKL025C"
                     /gene_synonym="ECM35"
                     /experiment="EXISTENCE:direct assay:GO:0000289
                     nuclear-transcribed mRNA poly(A) tail shortening
                     [PMID:8816488]"
                     /experiment="EXISTENCE:direct assay:GO:0003723 RNA binding
                     [PMID:24872509]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:direct assay:GO:0006281 DNA repair
                     [PMID:11953437]"
                     /experiment="EXISTENCE:direct assay:GO:0008143 poly(A)
                     binding [PMID:24872509]"
                     /experiment="EXISTENCE:direct assay:GO:0031251 PAN complex
                     [PMID:8816488]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006301
                     postreplication repair [PMID:11953437]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000289
                     nuclear-transcribed mRNA poly(A) tail shortening
                     [PMID:8816488]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0003723 RNA
                     binding [PMID:24872509]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0008143 poly(A)
                     binding [PMID:24872509]"
                     /experiment="EXISTENCE:physical interaction:GO:0006301
                     postreplication repair [PMID:11953437]"
                     /note="Essential subunit of the Pan2p-Pan3p
                     poly(A)-ribonuclease complex; poly (A) mRNA binding
                     subunit which recruits mRNA to the complex; the
                     Pan2p-Pan3p complex controls poly(A) tail length and
                     regulates the stoichiometry and activity of
                     postreplication repair complexes"
                     /codon_start=1
                     /product="Pan3p"
                     /protein_id="DAA09129.1"
                     /db_xref="SGD:S000001508"
                     /translation="MDKINPDWAKDIPCRNITIYGYCKKEKEGCPFKHSDNTTATTIN
                     DVPPPIDVGEATTPTMTSVPKFNAKVSASFTPMTVGSDSLTTVTNTTSAATNATGNIA
                     MAATSATASTVNPMINPIVNSSLVNNNNNNSNISISIPTTASSSNYDPFNAPIFTPSS
                     TSSIHTNANAHSFPFPSIANSGGININATDDNSNNMSMANNVPPPMQPPPIESSNLKY
                     PRIYPPPHSLLQYHLYAPEQPSSLKSLLKPNERSADQLFIPNNIREDLTKKNLSILQV
                     FPSSGKVIPSIVQDYFNLVPLNFNNNDFLNKTTLFKVFSNYDGKAYVLKRLPNIDKSM
                     NPNKISKIYQIWSKINCTNLIKFRDIFQTTKFGDLSICLVFDYYPNSLSLYDYHFVNF
                     PKFPITNNYLWIYLVQLTNVINSIHSQNLSIGNTLNWRKVLITGDPGRIKLSHCNFMD
                     LLFNDDTDTVVSSGGSTIEGQQQLDYKYLGELLFNLSINIENSNNNTAPKEYRLEEIT
                     PQSIDDMRQIDDKFKDVLKYLISDNGDSKKSIHDLTSHFYDKMFMVLESSQTYTEYME
                     SVLSRELENGRLFRLVNKLNCIFGRIESRIDINWSESGTKFPIILFYDYVFHQVDSNG
                     KPIMDLTHVLRCLNKLDAGIQEKLMLVTPDELNCIIISYKELKDLIESTFRSITQ"
     gene            complement(392526..393140)
                     /gene="URA6"
                     /locus_tag="YKL024C"
                     /gene_synonym="SOC8"
     mRNA            complement(392526..393140)
                     /gene="URA6"
                     /locus_tag="YKL024C"
                     /gene_synonym="SOC8"
                     /product="bifunctional uridylate/adenylate kinase"
     CDS             complement(392526..393140)
                     /gene="URA6"
                     /locus_tag="YKL024C"
                     /gene_synonym="SOC8"
                     /EC_number="2.7.4.14"
                     /experiment="EXISTENCE:direct assay:GO:0004017 adenylate
                     kinase activity [PMID:1333436]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:8391780]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:8391780]"
                     /experiment="EXISTENCE:direct assay:GO:0006139
                     nucleobase-containing compound metabolic process
                     [PMID:2549068]"
                     /experiment="EXISTENCE:direct assay:GO:0006207 'de novo'
                     pyrimidine nucleobase biosynthetic process [PMID:8391780]"
                     /experiment="EXISTENCE:direct assay:GO:0009041 uridylate
                     kinase activity [PMID:1655742|PMID:2549068]"
                     /experiment="EXISTENCE:genetic interaction:GO:0004017
                     adenylate kinase activity [PMID:1333436]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0009041
                     uridylate kinase activity [PMID:1655742]"
                     /note="Uridylate kinase; catalyzes the seventh enzymatic
                     step in the de novo biosynthesis of pyrimidines,
                     converting uridine monophosphate (UMP) into
                     uridine-5'-diphosphate (UDP)"
                     /codon_start=1
                     /product="bifunctional uridylate/adenylate kinase"
                     /protein_id="DAA09130.1"
                     /db_xref="SGD:S000001507"
                     /translation="MTAATTSQPAFSPDQVSVIFVLGGPGAGKGTQCEKLVKDYSFVH
                     LSAGDLLRAEQGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLI
                     DGFPRKMDQAISFERDIVESKFILFFDCPEDIMLERLLERGKTSGRSDDNIESIKKRF
                     NTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDVQDAIRDSL"
     gene            complement(393146..393373)
                     /gene="MIN9"
                     /locus_tag="YKL023C-A"
     mRNA            complement(393146..393373)
                     /gene="MIN9"
                     /locus_tag="YKL023C-A"
                     /product="Min9p"
     CDS             complement(393146..393373)
                     /gene="MIN9"
                     /locus_tag="YKL023C-A"
                     /note="Mitochondrial hypothetical protein"
                     /codon_start=1
                     /product="Min9p"
                     /protein_id="DAA09131.1"
                     /db_xref="SGD:S000113559"
                     /translation="MNPRYRFILRFYSSKKPTFHNTAPSKTNVNVPRANKSQSKGKHK
                     GKLLVLVGTLALVTSVISVNYQKNEPVEFLE"
     gene            393721..394554
                     /gene="SKA1"
                     /locus_tag="YKL023W"
     mRNA            393721..394554
                     /gene="SKA1"
                     /locus_tag="YKL023W"
                     /product="Ska1p"
     CDS             393721..394554
                     /gene="SKA1"
                     /locus_tag="YKL023W"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0034427
                     nuclear-transcribed mRNA catabolic process,
                     exonucleolytic, 3'-5' [PMID:31304628]"
                     /note="SKI complex-associated protein; involved in 3'-5'
                     degradation of long 3'UTR-containing mRNA, poorly
                     translated mRNA, and other RNA regions devoid of
                     ribosomes; proposed to assist the cytoplasmic exosome in a
                     Ska1-SKI complex when a direct interaction between the
                     ribosome and the SKI complex is absent"
                     /codon_start=1
                     /product="Ska1p"
                     /protein_id="DAA09132.2"
                     /db_xref="SGD:S000001506"
                     /translation="MNKEELLGFLLDDSIDSQKRCVTDQQAYSNWLKNDNDERTAHEE
                     SSSQSTIAALNKKKQTEAAQEDIEELLNGLEGIIGGADPRNLKSKSKRKTKKGGSKPR
                     EENVNTEKHIVMLEVEDFSDMSTHEDVNGASPSPNLDRSKKNEKRRKNAKELSYDELK
                     DKLEVTTRKSRLECKDLKKKVHGLERRNLELEQRLEELKIENQTLIEINNKLLKNTNE
                     DEINKSQRNKEKDRKRRERRTARRKDERKQEKKQEKKQDNKTSQSFPSSTDMNGQPIE
                     F"
     gene            complement(394726..397248)
                     /gene="CDC16"
                     /locus_tag="YKL022C"
     mRNA            complement(394726..397248)
                     /gene="CDC16"
                     /locus_tag="YKL022C"
                     /product="anaphase promoting complex subunit CDC16"
     CDS             complement(394726..397248)
                     /gene="CDC16"
                     /locus_tag="YKL022C"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:22932476]"
                     /experiment="EXISTENCE:direct assay:GO:0005680
                     anaphase-promoting complex [PMID:9469814]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:22932476]"
                     /experiment="EXISTENCE:direct assay:GO:0016567 protein
                     ubiquitination [PMID:16481473]"
                     /experiment="EXISTENCE:direct assay:GO:0031145
                     anaphase-promoting complex-dependent catabolic process
                     [PMID:8895471]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0016567 protein
                     ubiquitination [PMID:16481473]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031145
                     anaphase-promoting complex-dependent catabolic process
                     [PMID:16481473]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0032297
                     negative regulation of DNA-dependent DNA replication
                     initiation [PMID:9660930]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0061630
                     ubiquitin protein ligase activity [PMID:16481473]"
                     /experiment="EXISTENCE:physical interaction:GO:0005515
                     protein binding [PMID:29883473]"
                     /note="Subunit of the anaphase-promoting complex/cyclosome
                     (APC/C); which is a ubiquitin-protein ligase required for
                     degradation of anaphase inhibitors, including mitotic
                     cyclins, during the metaphase/anaphase transition;
                     required for sporulation; relocalizes to the cytosol in
                     response to hypoxia"
                     /codon_start=1
                     /product="anaphase promoting complex subunit CDC16"
                     /protein_id="DAA09133.1"
                     /db_xref="SGD:S000001505"
                     /translation="MKFCLYCCHCYIVICGKATHYYKSSKATSNLKSSNRVLMRNPMS
                     PSEQHSQHNSTLAASPFVSNVSAARTQQSLPTDAQNDRLQQPWNRTNTATSPYQSLAN
                     SPLIQKLQANIMTPHQPSANSNSNSNSITGNVVNDNNLLASMSKNSMFGSTIPSTLRK
                     VSLQREYKDSVDGVVRDEDNDEDVHNNGDAAANANNDRESKLGHNGPLTTTTLTTTTT
                     ATQLDVSELSAIERLRLWRFDALMQHMYRTAEYIADKVYNISNDPDDAFWLGQVYYNN
                     NQYVRAVELITRNNLDGVNILCRYLLGLSFVKLQRFDDALDVIGEYNPFSEDPSTTAA
                     NTMSNNGNNSNTSQPVTDGGIKMESSLCFLRGKIYFAQNNFNKARDAFREAILVDIKN
                     FEAFEMLLSKNLLTPQEEWDLFDSLDFKEFGEDKEIMKNLYKINLSKYINTEDITKSN
                     EILAKDYKLADNVDVVRSKVDICYTQCKFNECLELCETVLENDEFNTNILPAYIGCLY
                     ELSNKNKLFLLSHRLAETFPKSAITWFSVATYYMSLDRISEAQKYYSKSSILDPSFAA
                     AWLGFAHTYALEGEQDQALTAYSTASRFFPGMHLPKLFLGMQFMAMNSLNLAESYFVL
                     AYDICPNDPLVLNEMGVMYFKKNEFVKAKKYLKKALEVVKDLDPSSRTTISIQLNLGH
                     TYRKLNENEIAIKCFRCVLEKNDKNSEIHCSLGYLYLKTKKLQKAIDHLHKSLYLKPN
                     NSSATALLKNALELNVTLSLDASHPLIDKSNLMSQASKDKASLNKKRSSLTYDPVNMA
                     KRLRTQKEIFDQNNKALRKGGHDSKTGSNNADDDFDADMELE"
     gene            complement(397344..398750)
                     /gene="MAK11"
                     /locus_tag="YKL021C"
     mRNA            complement(397344..398750)
                     /gene="MAK11"
                     /locus_tag="YKL021C"
                     /product="Mak11p"
     CDS             complement(397344..398750)
                     /gene="MAK11"
                     /locus_tag="YKL021C"
                     /experiment="EXISTENCE:direct assay:GO:0016020 membrane
                     [PMID:2826479]"
                     /experiment="EXISTENCE:genetic interaction:GO:0000027
                     ribosomal large subunit assembly [PMID:17308036]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000027
                     ribosomal large subunit assembly [PMID:17308036]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000463
                     maturation of LSU-rRNA from tricistronic rRNA transcript
                     (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17308036]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000466
                     maturation of 5.8S rRNA from tricistronic rRNA transcript
                     (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17308036]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0042273
                     ribosomal large subunit biogenesis [PMID:7739558]"
                     /experiment="EXISTENCE:physical interaction:GO:0000027
                     ribosomal large subunit assembly [PMID:17308036]"
                     /note="Protein involved in an early step of 60S ribosomal
                     subunit biogenesis; essential for cell growth and
                     replication of killer M1 dsRNA virus; contains four
                     beta-transducin repeats"
                     /codon_start=1
                     /product="Mak11p"
                     /protein_id="DAA09134.1"
                     /db_xref="SGD:S000001504"
                     /translation="MLLNTTYTVFIFFLLRIIKFKIKAENFLEHEKLKTHGTSSRKDP
                     KGQVKNSCRKMSAIGDKNQFRIIVGSYEHNILCLSLDIPNQKENDAAKTPHFMPIFHF
                     QAHSLSIKCLAVSRRYLVSGSNDEHIRIYDLQKRKELGTLLSHQGSITALQFSHPASS
                     SEDAAVSKGSKNSKWLLSASEDHKIMVWRVKDWETVGTLKGHTARVNDVDIHPTNRIA
                     ISVSDDHSIRLWNLMTLRNAAVLKLRKYNTNGTCVRWLGAKGDYFAVGLRDRVLIYET
                     GSAKVFKEIVFQRKTLMHIETHILPFDNKEYLSVGISDGNVHFYPCEELFEKVEENEK
                     QEDDDDKEDISPAFSLLGHTNRIKDFKFYTNEFGTYLVTIGSDGKIVVWDMSTKEQVA
                     VYDCGERLNCLTLCDESIEKYNTMKKRDAETADIGDQSEVESDTEELKKIMFGEKKKL
                     NKKKRKQLKKSKVSVELE"
     gene            complement(398832..402080)
                     /gene="SPT23"
                     /locus_tag="YKL020C"
     mRNA            complement(398832..402080)
                     /gene="SPT23"
                     /locus_tag="YKL020C"
                     /product="Spt23p"
     CDS             complement(398832..402080)
                     /gene="SPT23"
                     /locus_tag="YKL020C"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:11007476]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0030176 integral
                     component of endoplasmic reticulum membrane
                     [PMID:11007476]"
                     /experiment="EXISTENCE:genetic interaction:GO:0030466
                     silent mating-type cassette heterochromatin assembly
                     [PMID:11063674]"
                     /experiment="EXISTENCE:genetic interaction:GO:0045944
                     positive regulation of transcription by RNA polymerase II
                     [PMID:9927444]"
                     /experiment="EXISTENCE:genetic interaction:GO:0070417
                     cellular response to cold [PMID:11855848]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045944
                     positive regulation of transcription by RNA polymerase II
                     [PMID:11557770]"
                     /note="ER membrane protein involved in regulation of OLE1
                     transcription; inactive ER form dimerizes and one subunit
                     is then activated by ubiquitin/proteasome-dependent
                     processing followed by nuclear targeting; SPT23 has a
                     paralog, MGA2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Spt23p"
                     /protein_id="DAA09135.1"
                     /db_xref="SGD:S000001503"
                     /translation="MMSGTGNVSSMLHSYSANIQHNDGSPDLDLLESELLDIALLNSG
                     SSLQDPGLLSLNQEKMITAGTTTPGKEDEGELRDDIASLQGLLDRHVQFGRKLPLRTP
                     YANPLDFININPQSLPLSLEIIGLPKVSRVETQMKLSFRIRNAHARKNFFIHLPSDCI
                     AKDKFFTSSDDPTNLTIPNRDINERTLFLDAFLLCASNNNSNNFKQTYVCNRCINREK
                     RRASRRKSGLNDNSIWQNNENKRAIIFNSKQLFIISNNGLSGNSNCINFDLPTRIVCY
                     CRHHKATNGFVVLFLLRDHNGDILAKTITDPIMIMDKKNASNTTTPTSTSNAQVSPMT
                     NDTRSFSSPQSDLNFPSEFPLPSNSKNFVISTNCMLDSNCNNNNNDNDNKNNIKTNTA
                     MMNNNRHFPSPNSSSEDSNHSFSDIHFSNNNDNNLHRSLDSWSSTGFNSSSNPALTTL
                     TSDFSAASARHTGKRQRSVNEPFMSTPNTFSRLPQKFIDSSKDISNHNSVPVALNNKP
                     SIQRVIPAQGSINGGIEVTLLGSKFKQGLIIKFGENIALSSQCWNESTMVTYLPPSSK
                     PGPVLVTIVDPSETSMRNNSNSSVSTSNSTNDILHLNKYTGEKAIFTYVDDTDRQLIE
                     LALQIVGLKMNGKLEDARNIAKRIVGSDSSPSNNNAGLHSQNSSLNSYTNMMRNINDE
                     QLITEVIKSFKRNNNLSTVNLSMCDVRGRTLLHLAAFNNWYSLVSLLIKYGSHLNDQD
                     LFGFTPLHMACINGDLRIIRLLLECNVNIMKKTRNGFIAKQFFLMNYTVNKTRYSNYE
                     TSLFDDILTRLTKNTTGSSDTQPFERNVSQSSFNSSLFDDDDADHDYVQERKYLLADS
                     AALAPEQSNCNDNTSFSILDSDSGYDISDCESSSDEIALEFFNTHKIKDFSSKPNEIP
                     KTTKTSIEPDGSLWNRMLTRLNDELPKYEDLFPKKPKNWELGSKSVEIGPDNSAQMTV
                     DDSQTSSEDDELEALQVGFNTIFSKKQNFQNDKMLLFFWIPLTLVLLLCFTLSNLGKD
                     DDMFHNLSKIVQEYLRIGLAKVLLGNERMKTSFKMQLSKFQNNNILNDMRVN"
     gene            402568..403518
                     /gene="RAM2"
                     /locus_tag="YKL019W"
     mRNA            402568..403518
                     /gene="RAM2"
                     /locus_tag="YKL019W"
                     /product="bifunctional protein farnesyltransferase/protein
                     geranylgeranyltransferase"
     CDS             402568..403518
                     /gene="RAM2"
                     /locus_tag="YKL019W"
                     /EC_number="2.5.1.58"
                     /EC_number="2.5.1.59"
                     /experiment="EXISTENCE:direct assay:GO:0004660 protein
                     farnesyltransferase activity [PMID:1763050]"
                     /experiment="EXISTENCE:direct assay:GO:0004661 protein
                     geranylgeranyltransferase activity [PMID:2034682]"
                     /experiment="EXISTENCE:direct assay:GO:0004662
                     CAAX-protein geranylgeranyltransferase activity
                     [PMID:1400380]"
                     /experiment="EXISTENCE:direct assay:GO:0005953
                     CAAX-protein geranylgeranyltransferase complex
                     [PMID:1400380]"
                     /experiment="EXISTENCE:direct assay:GO:0005965 protein
                     farnesyltransferase complex [PMID:1763050]"
                     /experiment="EXISTENCE:direct assay:GO:0007323 peptide
                     pheromone maturation [PMID:1763050]"
                     /experiment="EXISTENCE:direct assay:GO:0018343 protein
                     farnesylation [PMID:1763050]"
                     /experiment="EXISTENCE:direct assay:GO:0018344 protein
                     geranylgeranylation [PMID:1400380]"
                     /note="Alpha subunit of farnesyltransferase and
                     geranylgeranyltransferase-I; farnesyltransferase
                     (Ram2p-Ram1p heterodimer) catalyzes the addition of
                     15-carbon isoprenoid farnesyl to substrate proteins
                     containing a CAAX consensus motif; type I
                     geranylgeranyltransferase (Ram2p-Cdc43p heterodimer)
                     catalyzes the addition of the 20-carbon isoprenoid
                     geranylgeranyl to substrate proteins containing a CaaL
                     consensus motif; required for membrane localization of Ras
                     proteins and a-factor"
                     /codon_start=1
                     /product="bifunctional protein farnesyltransferase/protein
                     geranylgeranyltransferase"
                     /protein_id="DAA09136.1"
                     /db_xref="SGD:S000001502"
                     /translation="MEEYDYSDVKPLPIETDLQDELCRIMYTEDYKRLMGLARALISL
                     NELSPRALQLTAEIIDVAPAFYTIWNYRFNIVRHMMSESEDTVLYLNKELDWLDEVTL
                     NNPKNYQIWSYRQSLLKLHPSPSFKRELPILKLMIDDDSKNYHVWSYRKWCCLFFSDF
                     QHELAYASDLIETDIYNNSAWTHRMFYWVNAKDVISKVELADELQFIMDKIQLVPQNI
                     SPWTYLRGFQELFHDRLQWDSKVVDFATTFIGDVLSLPIGSPEDLPEIESSYALEFLA
                     YHWGADPCTRDNAVKAYSLLAIKYDPIRKNLWHHKINNLN"
     gene            complement(403580..403879)
                     /gene="MCO12"
                     /locus_tag="YKL018C-A"
     mRNA            complement(403580..403879)
                     /gene="MCO12"
                     /locus_tag="YKL018C-A"
                     /product="Mco12p"
     CDS             complement(403580..403879)
                     /gene="MCO12"
                     /locus_tag="YKL018C-A"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /note="Putative mitochondrial hypothetical protein;
                     identified by homology; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm"
                     /codon_start=1
                     /product="Mco12p"
                     /protein_id="DAA09137.1"
                     /db_xref="SGD:S000007615"
                     /translation="MLGMIRWVVEGTLVAMLLSAIRRETGMIFFYNQYQLGGWIHRYL
                     SWGEMCYTRTLKMVKRSKFFRKQLNEDGFGRINDSGPKRRGRDQSQYSSRFVELD"
     gene            404102..405091
                     /gene="SWD2"
                     /locus_tag="YKL018W"
                     /gene_synonym="CPS35"
                     /gene_synonym="SAF37"
     mRNA            404102..405091
                     /gene="SWD2"
                     /locus_tag="YKL018W"
                     /gene_synonym="CPS35"
                     /gene_synonym="SAF37"
                     /product="WD-repeat containing protein SWD2"
     CDS             404102..405091
                     /gene="SWD2"
                     /locus_tag="YKL018W"
                     /gene_synonym="CPS35"
                     /gene_synonym="SAF37"
                     /experiment="EXISTENCE:direct assay:GO:0005847 mRNA
                     cleavage and polyadenylation specificity factor complex
                     [PMID:12819204]"
                     /experiment="EXISTENCE:direct assay:GO:0042800 histone
                     methyltransferase activity (H3-K4 specific)
                     [PMID:11742990|PMID:11805083]"
                     /experiment="EXISTENCE:direct assay:GO:0051568 histone
                     H3-K4 methylation
                     [PMID:11742990|PMID:11752412|PMID:11805083]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000723
                     telomere maintenance [PMID:15146080]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031124 mRNA
                     3'-end processing [PMID:15146080]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0031126
                     sno(s)RNA 3'-end processing [PMID:15146080]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0034729 histone
                     H3-K79 methylation [PMID:18083099]"
                     /experiment="EXISTENCE:physical interaction:GO:0048188
                     Set1C/COMPASS complex
                     [PMID:11687631|PMID:11742990|PMID:11752412]"
                     /note="Subunit of the COMPASS (Set1C) histone H3K4
                     methyltransferase complex; required for Set1C stability
                     and optimal activity; COMPASS methylates histone H3 on lys
                     4 and is involved in telomeric silencing; subunit of CPF
                     (cleavage and polyadenylation factor), a complex involved
                     in RNAP II transcription termination"
                     /codon_start=1
                     /product="WD-repeat containing protein SWD2"
                     /protein_id="DAA09138.1"
                     /db_xref="SGD:S000001501"
                     /translation="MTTVSINKPNLLKFKHVKSFQPQEKDCGPVTSLNFDDNGQFLLT
                     SSSNDTMQLYSATNCKFLDTIASKKYGCHSAIFTHAQNECIYSSTMKNFDIKYLNLET
                     NQYLRYFSGHGALVNDLKMNPVNDTFLSSSYDESVRLWDLKISKPQVIIPSLVPNCIA
                     YDPSGLVFALGNPENFEIGLYNLKKIQEGPFLIIKINDATFSQWNKLEFSNNGKYLLV
                     GSSIGKHLIFDAFTGQQLFELIGTRAFPMREFLDSGSACFTPDGEFVLGTDYDGRIAI
                     WNHSDSISNKVLRPQGFIPCVSHETCPRSIAFNPKYSMFVTADETVDFYVYDE"
     gene            complement(405190..407241)
                     /gene="HCS1"
                     /locus_tag="YKL017C"
                     /gene_synonym="DIP1"
     mRNA            complement(405190..407241)
                     /gene="HCS1"
                     /locus_tag="YKL017C"
                     /gene_synonym="DIP1"
                     /product="ATP-dependent 5'-3' DNA helicase HCS1"
     CDS             complement(405190..407241)
                     /gene="HCS1"
                     /locus_tag="YKL017C"
                     /gene_synonym="DIP1"
                     /EC_number="3.6.4.12"
                     /experiment="EXISTENCE:direct assay:GO:0033203 DNA
                     helicase A complex [PMID:9341218]"
                     /experiment="EXISTENCE:direct assay:GO:0043139 5'-3' DNA
                     helicase activity [PMID:8257676|PMID:9341218]"
                     /experiment="EXISTENCE:direct assay:GO:0043601 nuclear
                     replisome [PMID:8257676]"
                     /note="Hexameric DNA polymerase alpha-associated DNA
                     helicase A; involved in lagging strand DNA synthesis;
                     contains single-stranded DNA stimulated ATPase and dATPase
                     activities; replication protein A stimulates helicase and
                     ATPase activities"
                     /codon_start=1
                     /product="ATP-dependent 5'-3' DNA helicase HCS1"
                     /protein_id="DAA09139.1"
                     /db_xref="SGD:S000001500"
                     /translation="MNKELASKFLSSIKHEREQDIQTTSRLLTTLSIQQLVQNGLAIN
                     NIHLENIRSGLIGKLYMELGPNLAVNDKIQRGDIKVGDIVLVRPAKTKVNTKTKPKVK
                     KVSEDSNGEQAECSGVVYKMSDTQITIALEESQDVIATTFYSYSKLYILKTTNVVTYN
                     RMESTMRKLSEISSPIQDKIIQYLVNERPFIPNTNSFQNIKSFLNPNLNDSQKTAINF
                     AINNDLTIIHGPPGTGKTFTLIELIQQLLIKNPEERILICGPSNISVDTILERLTPLV
                     PNNLLLRIGHPARLLDSNKRHSLDILSKKNTIVKDISQEIDKLIQENKKLKNYKQRKE
                     NWNEIKLLRKDLKKREFKTIKDLIIQSRIVVTTLHGSSSRELCSLYRDDPNFQLFDTL
                     IIDEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDKNVIHNLETTLFD
                     RIIKIFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLIDLPTVDAT
                     PSEDDDDTKIPLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENLRSFNVPE
                     NSIGVISPYNAQVSHLKKLIHDELKLTDIEISTVDGFQGREKDVIILSLVRSNEKFEV
                     GFLKEERRLNVAMTRPRRQLVVVGNIEVLQRCGNKYLKSWSEWCEENADVRYPNIDDY
                     L"
     gene            complement(407465..407989)
                     /gene="ATP7"
                     /locus_tag="YKL016C"
     mRNA            complement(407465..407989)
                     /gene="ATP7"
                     /locus_tag="YKL016C"
                     /product="F1F0 ATP synthase subunit d"
     CDS             complement(407465..407989)
                     /gene="ATP7"
                     /locus_tag="YKL016C"
                     /experiment="EXISTENCE:direct assay:GO:0000274
                     mitochondrial proton-transporting ATP synthase, stator
                     stalk [PMID:18937496]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0015986 ATP
                     synthesis coupled proton transport [PMID:20691145]"
                     /experiment="EXISTENCE:direct assay:GO:0046933
                     proton-transporting ATP synthase activity, rotational
                     mechanism [PMID:20691145]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000274
                     mitochondrial proton-transporting ATP synthase, stator
                     stalk [PMID:1832157]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015986 ATP
                     synthesis coupled proton transport [PMID:1832157]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0046933
                     proton-transporting ATP synthase activity, rotational
                     mechanism [PMID:1832157]"
                     /note="Subunit d of the stator stalk of mitochondrial F1F0
                     ATP synthase; F1F0 ATP synthase is a large, evolutionarily
                     conserved enzyme complex required for ATP synthesis"
                     /codon_start=1
                     /product="F1F0 ATP synthase subunit d"
                     /protein_id="DAA09140.1"
                     /db_xref="SGD:S000001499"
                     /translation="MSLAKSAANKLDWAKVISSLRITGSTATQLSSFKKRNDEARRQL
                     LELQSQPTEVDFSHYRSVLKNTSVIDKIESYVKQYKPVKIDASKQLQVIESFEKHAMT
                     NAKETESLVSKELKDLQSTLDNIQSARPFDELTVDDLTKIKPEIDAKVEEMVKKGKWD
                     VPGYKDRFGNLNVM"
     gene            408544..411483
                     /gene="PUT3"
                     /locus_tag="YKL015W"
     mRNA            408544..411483
                     /gene="PUT3"
                     /locus_tag="YKL015W"
                     /product="Put3p"
     CDS             408544..411483
                     /gene="PUT3"
                     /locus_tag="YKL015W"
                     /experiment="EXISTENCE:curator inference:GO:0005634
                     nucleus [PMID:1986247]"
                     /experiment="EXISTENCE:direct assay:GO:0000978 RNA
                     polymerase II cis-regulatory region sequence-specific DNA
                     binding [PMID:1986247|PMID:8846888]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0043565
                     sequence-specific DNA binding
                     [PMID:19111667|PMID:19158363]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0000972
                     transcription-dependent tethering of RNA polymerase II
                     gene DNA at nuclear periphery [PMID:22579222]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0001228
                     DNA-binding transcription activator activity, RNA
                     polymerase II-specific [PMID:8846888]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0045944
                     positive regulation of transcription by RNA polymerase II
                     [PMID:2689862|PMID:8846888]"
                     /experiment="EXISTENCE:mutant phenotype:GO:2001158
                     positive regulation of proline catabolic process to
                     glutamate [PMID:2689862]"
                     /note="Transcriptional activator; binds specific gene
                     recruitment sequences and is required for DNA zip
                     code-mediated targeting of genes to nuclear periphery;
                     regulates proline utilization genes, constitutively binds
                     PUT1 and PUT2 promoters as a dimer, undergoes
                     conformational change to form active state; binds other
                     promoters only under activating conditions; differentially
                     phosphorylated in presence of different nitrogen sources;
                     has a Zn(2)-Cys(6) binuclear cluster domain"
                     /codon_start=1
                     /product="Put3p"
                     /protein_id="DAA09141.1"
                     /db_xref="SGD:S000001498"
                     /translation="MVTDQGSRHSIQSKQPAYVNKQPQKRQQRSSVACLSCRKRHIKC
                     PGGNPCQKCVTSNAICEYLEPSKKIVVSTKYLQQLQKDLNDKTEENNRLKALLLERPV
                     SVRGKDNSDDDERHINNAPSSDTLEVSSAPAAPIFDLMSNSNTASDNDNDDDNSNRIT
                     NNRSYDHSLEKYYKKAISIFKQPANANGENGNGANGHEDDDEDDEEISTNFAQRSGRL
                     IESHNGFHYFVGSSSMTLFGLEIQSLVTKYISVKNFRPLPINTKNKILNSNLNPAISS
                     FINSNNYLFSSYNFLNPISTIVNLNSINDNLSPLMFKIILKSDTDGSSGQEEVIQFQL
                     PSYNYTKLLIDCFINYNDGCFYFFNEGLVKCGINKLYLENKWLYYDNTKKALDNENDP
                     ILQAVWFCKILLILAVGEMYLGSINNEMLKNYSNQPKLPGSKFFQMGSKIFNCLFSSE
                     RLENVTKKGGIEVLLLYAFFLQVADYTLASYFYFGQALRTCLILGLHVDSQSDTLSRY
                     EIEHHRRLWWTVYMFERMLSSKAGLPLSFTDYTISTALPADIDDETIEEKNSHYVFRK
                     AELISNCVTIVKINAQILSKLYQRQPETNIIITLKVVIKQLLEWRNNLSDSLQVDFTQ
                     KDEDFKISRLSTNMFTEYFQGINLAVRPLLFHFASIQLKRFKTSNTFVNLQNYSATIS
                     SLLTCSLHASVNTIRSLWSLLQNSMLAMFSYMDREYLFTSSCTLLLFNTAFGIHEQTL
                     YHLDHSLEIFTQMRNLGNIPAGLRRAQLLTLMANLDFHGIMNDLITKYNDILKFDSMN
                     CENDNIVEDSNEPKRETEKCKPHKDGDRIDPSIIDCDKSNTNTNMIKNESISNIVSIL
                     PEGAKPTLTDYSNGNNDVNDINVNNSEPSTFFDIITASLENSYQTTLTEKGSQVMEKN
                     MDQLDSVHNLNDDDLQQLLEDLGNIDHSDEKLWKEITDQAMWLGNTMDPTAAAGSEID
                     FTDYLGP"
     gene            complement(411619..416913)
                     /gene="URB1"
                     /locus_tag="YKL014C"
                     /gene_synonym="NPA1"
     mRNA            complement(411619..416913)
                     /gene="URB1"
                     /locus_tag="YKL014C"
                     /gene_synonym="NPA1"
                     /product="Urb1p"
     CDS             complement(411619..416913)