LOCUS BC150213 3978 bp mRNA linear HUM 17-JUL-2007
DEFINITION Homo sapiens leucyl-tRNA synthetase, mRNA (cDNA clone MGC:165104
IMAGE:40148958), complete cds.
ACCESSION BC150213
VERSION BC150213.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3978)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3978)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-JUL-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Novartis Institute for Biomedical Research
cDNA Library Preparation: Novartis Institute for Biomedical
Research
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 306 Row: p Column: 11.
FEATURES Location/Qualifiers
source 1..3978
/db_xref="H-InvDB:HIT000435739"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:165104 IMAGE:40148958"
/tissue_type="Donated clones,Novartis FGA collection"
/clone_lib="NIH_MGC_417"
/lab_host="DH5a"
/note="Vector: pCMV-SPORT6"
gene 1..3978
/gene="LARS"
/gene_synonym="hr025Cl"
/gene_synonym="HSPC192"
/gene_synonym="LARS1"
/gene_synonym="LEURS"
/gene_synonym="LEUS"
/gene_synonym="LRS"
/gene_synonym="PIG44"
/gene_synonym="RNTLS"
/db_xref="GeneID:51520"
/db_xref="HGNC:HGNC:6512"
/db_xref="MIM:151350"
CDS 146..3676
/gene="LARS"
/gene_synonym="hr025Cl"
/gene_synonym="HSPC192"
/gene_synonym="LARS1"
/gene_synonym="LEURS"
/gene_synonym="LEUS"
/gene_synonym="LRS"
/gene_synonym="PIG44"
/gene_synonym="RNTLS"
/codon_start=1
/product="LARS protein"
/protein_id="AAI50214.1"
/db_xref="GeneID:51520"
/db_xref="HGNC:HGNC:6512"
/db_xref="MIM:151350"
/translation="MAERKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKG
KYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACAD
KLKREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGI
MKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFV
RWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYP
SKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETVNGDIFICTQKAARNM
SYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSV
PSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELK
IQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYM
EPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLG
WLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAESPLG
IRPQQMTKEVWDYVFFKEAPFPKTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHL
SYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMR
LALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFA
SELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQT
LLLAPFCPHLCEHIWTLLGKPDSIMNASWPVAGPVNEVLIHSSQYLMEVTHDLRLRLK
NYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVI
ASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQLEFDEKAVLMENIVYLTNS
LELEHIEVKFASEAEDKIREDCCPGKPLNVFRIEPGVSVSLVNPQPSNGHFSTKIEIR
QGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTPISEHAV
FNVDLMSKKIHLTENGIRVDIGDTIIYLVH"
BASE COUNT 1277 a 721 c 920 g 1060 t
ORIGIN
1 gatgattgcc tcagcaggtg tgaagcgtgt gctttagttt cgtgggaggc ctggcatccc
61 cgagagggag gggaaaggta accactcctt tgtggaggtc gccagggtca ttgtcgtgga
121 tttgcacagt cggctgggcg gtgcaatggc ggaaagaaaa ggaacagcca aagtggactt
181 tttgaagaag attgagaaag aaatccaaca gaaatgggat actgagagag tgtttgaggt
241 caatgcatct aatttagaga aacagaccag caagggcaag tattttgtaa ccttcccata
301 tccatatatg aatggacgcc ttcatttggg acacacgttt tctttatcca aatgtgagtt
361 tgctgtaggg taccagcgat tgaaaggaaa atgttgtctg tttccctttg gcctgcactg
421 tactggaatg cctattaagg catgtgctga taagttgaaa agagaaatag agctgtatgg
481 ttgcccccct gattttccag atgaagaaga ggaagaggaa gaaaccagtg ttaaaacaga
541 agatataata attaaggata aagctaaagg aaaaaagagt aaagctgctg ctaaagctgg
601 atcttctaaa taccagtggg gcattatgaa atcccttggc ctgtctgatg aagagatagt
661 aaaattttct gaagcagaac attggcttga ttatttcccg ccactggcta ttcaggattt
721 aaaaagaatg ggtttgaagg tagactggcg tcgttccttc atcaccactg atgttaatcc
781 ttactatgat tcatttgtca gatggcaatt tttaacatta agagaaagaa acaaaattaa
841 atttgggaag cggtatacaa tttactctcc gaaagatgga cagccttgca tggatcatga
901 tagacaaact ggagagggtg ttggacctca ggaatatact ttactcaaat tgaaggtgct
961 tgagccatac ccatctaaat taagtggcct gaaaggtaaa aatattttct tggtggctgc
1021 tactctcaga cctgagacca tgtttgggca gacaaattgt tgggttcgtc ctgatatgaa
1081 gtacattgga tttgagacgg tgaatggtga tatattcatc tgtacccaaa aagcagccag
1141 gaatatgtca taccagggct ttaccaaaga caatggcgtg gtgcctgttg ttaaggaatt
1201 aatgggggag gaaattcttg gtgcatcact ttctgcacct ttaacatcat acaaggtgat
1261 ctatgttctc ccaatgctaa ctattaagga ggataaaggc actggtgtgg ttacaagtgt
1321 tccttccgac tcccctgatg atattgctgc cctcagagac ttgaagaaaa agcaagcctt
1381 acgagcaaaa tatggaatta gagatgacat ggtcttgcca tttgagccgg tgccagtcat
1441 tgaaatccca ggttttggaa atctttctgc tgtaaccatt tgtgatgagt tgaaaattca
1501 gagccagaat gaccgggaaa aacttgcaga agcaaaggag aagatatatc taaaaggatt
1561 ttatgagggt atcatgttgg tggatggatt taaaggacag aaggttcaag atgtaaagaa
1621 gactattcag aaaaagatga ttgacgctgg agatgcactt atttacatgg aaccagagaa
1681 acaagtgatg tccaggtcgt cagatgaatg tgttgtggct ctgtgtgacc agtggtactt
1741 ggattatgga gaagagaatt ggaagaaaca gacatctcag tgcttgaaga acctggaaac
1801 attctgtgag gagaccagga ggaattttga agccacctta ggttggctac aagaacatgc
1861 ttgctcaaga acttatggtc taggcactca cctgccttgg gatgagcagt ggctgattga
1921 atcactttct gactccacta tttacatggc attttacaca gttgcacacc tattgcaggg
1981 gggtaacttg catggacagg cagagtctcc gctgggcatt agaccgcaac agatgaccaa
2041 ggaagtttgg gattatgttt tcttcaagga ggctccattt cctaagactc agattgcaaa
2101 ggaaaaatta gatcagttaa agcaggagtt tgaattctgg tatcctgttg atcttcgcgt
2161 ctctggcaag gatcttgttc caaatcatct ttcatattac ctttataatc atgtggctat
2221 gtggccggaa caaagtgaca aatggcctac agctgtgaga gcaaatggac atctcctcct
2281 gaactctgag aagatgtcaa aatccacagg caacttcctc actttgaccc aagctattga
2341 caaattttca gcagatggaa tgcgtttggc tctggctgat gctggtgaca ctgtagaaga
2401 tgccaacttt gtggaagcca tggcagatgc aggtattctc cgtctgtaca cctgggtaga
2461 gtgggtgaaa gaaatggttg ccaactggga cagcctaaga agtggtcctg ccagcacttt
2521 caatgataga gtttttgcca gtgaattgaa tgcaggaatt ataaaaacag atcaaaacta
2581 tgaaaagatg atgtttaaag aagctttgaa aacagggttt tttgagtttc aggccgcaaa
2641 agataagtac cgtgaattgg ctgtggaagg gatgcacaga gaacttgtgt tccggtttat
2701 tgaagttcag acacttctcc tcgctccatt ctgtccacat ttgtgtgagc acatctggac
2761 actcctggga aagcctgact caattatgaa tgcttcatgg cctgtggcag gtcctgttaa
2821 tgaagtttta atacactcct cacagtatct tatggaagta acacatgacc ttagactacg
2881 actcaagaac tatatgatgc cagctaaagg gaagaagact gacaaacaac ccctgcagaa
2941 gccctcacat tgcaccatct atgtggcaaa gaactatcca ccttggcaac ataccaccct
3001 gtctgttcta cgtaaacact ttgaggccaa taacggaaaa ctgcctgaca acaaagtcat
3061 tgctagtgaa ctaggcagta tgccagaact gaagaaatac atgaagaaag tcatgccatt
3121 tgttgccatg attaaggaaa atctggagaa gatggggcct cgtattctgg atttgcaatt
3181 agaatttgat gaaaaggctg tgcttatgga gaatatagtc tatctgacta attcgcttga
3241 gctagaacac atagaagtca agtttgcctc cgaagcagaa gataaaatca gggaagactg
3301 ctgtcctggg aaaccactta atgtttttag aatagaacct ggtgtgtccg tttctctggt
3361 gaatccccag ccatccaatg gccacttctc aaccaaaatt gaaatcaggc aaggagataa
3421 ctgtgattcc ataatcaggc gtttaatgaa aatgaatcga ggaattaaag acctttccaa
3481 agtgaaactg atgagatttg atgatccact gttggggcct cgacgagttc ctgtcctggg
3541 aaaggagtac accgagaaga cccccatttc tgagcatgct gttttcaatg tggacctcat
3601 gagcaagaaa attcatctga ctgagaatgg gataagggtg gatattggcg atacaataat
3661 ctatctggtt cattaaactc atgcacattg gagatttatc ctggtttctt aggaatacta
3721 ctactctgat tgtgtctact gattggctat cagaacctta ggctggacct aaatagattg
3781 atttcatttc taaccatcca attctgcatg tattcataat tctatcaagt catctttgat
3841 tcctggacct aataaatttt ttttcccttt caaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3901 caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3961 aaaaaaaaaa aaaaaaaa
//