LOCUS BC144266 3817 bp mRNA linear HUM 08-JAN-2009
DEFINITION Homo sapiens AF4/FMR2 family, member 3, mRNA (cDNA clone MGC:177803
IMAGE:9052786), complete cds.
ACCESSION BC144266
VERSION BC144266.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3817)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3817)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 17 Row: H Column: 15.
FEATURES Location/Qualifiers
source 1..3817
/db_xref="H-InvDB:HIT000502692"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:177803 IMAGE:9052786"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_362"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: GACTAGTT"
gene 1..3817
/gene="AFF3"
/gene_synonym="MLLT2-like"
/db_xref="GeneID:3899"
/db_xref="HGNC:HGNC:6473"
/db_xref="MIM:601464"
CDS 20..3775
/gene="AFF3"
/gene_synonym="MLLT2-like"
/codon_start=1
/product="AF4/FMR2 family, member 3"
/protein_id="AAI44267.1"
/db_xref="GeneID:3899"
/db_xref="HGNC:HGNC:6473"
/db_xref="MIM:601464"
/translation="MDSFDLALLQEWDLESLWGEDILNQRNDSLVVEFQSSASRCRSV
YEPDRNALRRKERERRNQETQQDDGTFNSSYSLFSEPYKTNKGDELSNRIQNTLGNYD
EMKDFLTDRSNQSHLVGVPKPGVPQTPVNKIDEHFVADSRAQNQPSSICSTTTSTPAA
VPVQQSKRGTMGWQKAGHPPSDGQQRATQQGSLRTLLGDGVGRQQPRAKQVCNVEVGL
QTQERPPAMAAKHSSSGHCVQNFPPSLASKPSLVQQKPTAYVRPMDGQDQAPDESPKL
KSSSETSVHCTSYRGVPASKPEPARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREM
TWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDNGTSNTSMLE
DDLKLSSDEEENEQQAAQRTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSS
SDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVNPHKPPIL
IQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPG
SKGVKQKSPPAAVAVAVSAAAPPPAVPCAPAENAPAPARRSAGKKPTRRTERTSAGDG
ANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGLSR
IVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANG
GSGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNELLSPLKDSDEIRSLWVKIDLT
LLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYRE
IKKSQGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKH
KYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQPHGGDLTKAAHNNSENIPLHKSR
PQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYA
EAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAAL
CYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMS
PNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMAD
NLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRNSAHLS"
BASE COUNT 1043 a 1147 c 982 g 645 t
ORIGIN
1 gacgctgaca cctcccacca tggacagctt cgacttagcc ctgctccagg aatgggacct
61 cgagtcactg tggggtgaag acatcttaaa ccagaggaat gactctctag ttgtggaatt
121 tcagtcatca gccagcagat gcaggagtgt ctatgaacca gatagaaatg cattacggag
181 gaaagaacga gaaagaagaa atcaagaaac tcaacaggat gatggcacgt ttaattctag
241 ttactctctc ttcagtgagc cctacaagac taacaagggg gatgaactct ccaaccggat
301 ccagaacact ttaggcaatt atgatgaaat gaaagacttt ttaactgata gatccaatca
361 gagtcatctc gttggagttc ccaaacctgg ggttcctcag actcctgtga acaagatcga
421 tgaacatttt gttgcagatt caagagccca gaaccagccc tcgtctatct gtagcactac
481 aacttccaca ccagcagctg tccccgtgca gcagagtaag agaggcacta tgggctggca
541 gaaggctggg cacccaccct ctgacggcca acagagagca acacaacagg gctctctcag
601 gaccttgctt ggagatggtg ttggcagaca gcagcctcgg gccaaacaag tgtgcaatgt
661 ggaggtgggc cttcagaccc aggagaggcc acctgccatg gcggccaagc acagcagcag
721 cggacactgt gttcagaact ttcctccatc cctagcttca aaacccagcc tggtccagca
781 gaaaccgacc gcgtatgtga ggccaatgga cggccaagat caggcccctg atgagtctcc
841 taagctgaag tcgtcttcgg aaaccagcgt gcactgcaca tcatacaggg gagtccctgc
901 cagcaagccg gagcctgcca gagccaaggc caagctctcc aagttcagca tccccaagca
961 gggggaggag agtagatctg gagaaaccaa cagctgtgtt gaagaaataa tccgggagat
1021 gacctggctt ccaccacttt ctgctattca agcacctggc aaagtggaac caaccaaatt
1081 tccatttcca aataaggact ctcagcttgt atcctctgga cacaataatc caaagaaagg
1141 tgatgcagag ccagagagtc cagacaatgg cacatcgaat acatcaatgc tggaagatga
1201 ccttaagcta agcagtgatg aagaggagaa tgaacagcag gcagctcaga gaacggctct
1261 ccgcgctctc tctgacagcg ccgtggtcca gcagcccaac tgcagaacct cggtgccttc
1321 cagcaagggc agcagcagca gcagcagcag cggcagcagc agctcctcca gcgactcaga
1381 gagcagctcc ggatctgact cggagaccga gagcagctcc agcgagagtg agggcagcaa
1441 gcccccccac ttctccagcc ccgaggctga accggcatcc tctaacaagt ggcagctgga
1501 taaatggcta aacaaagtta atccccacaa gcctcctatt ctgatccaaa atgaaagcca
1561 cgggtcagag agcaatcagt actacaaccc ggtgaaagag gacgtccagg actgtgggaa
1621 agtccccgac gtttgccagc ccagcctgag agagaaggag atcaagagca cttgcaagga
1681 ggagcaaagg ccaaggacag ccaacaaggc ccctgggagt aaaggcgtga agcagaagtc
1741 cccgcccgcg gccgtggccg tggcggtgag cgcagccgcc ccgccacccg cagtgccctg
1801 tgcgcccgcg gagaacgcgc ccgcgcctgc ccggaggtcc gcgggcaaga agcccaccag
1861 gcgcaccgag aggacctcag ccggggacgg cgccaactgc caccggcccg aggagcccgc
1921 ggccgcggac gcgctgggga cgagcgtggt ggtccccccg gagcccacca aaaccaggcc
1981 ctgtggcaac aacagagcga gccaccgcaa ggagctgcgc tcctccgtga cctgcgagaa
2041 gcgccgcacg cgggggctaa gcaggatcgt ccccaaatcc aaggagttca ttgagacaga
2101 gtcgtcatct tcatcctcct cctcggactc cgacctggag tccgagcagg aggagtaccc
2161 tctgtccaaa gcacagaccg tggctgcctc tgcctcctcc gggaatgatc agaggctgaa
2221 ggaggccgct gccaacgggg gcagtggtcc tagggcccct gtaggctcca tcaacgccag
2281 gaccaccagt gacatcgcca aggagctgga ggagcagttc tacacactgg tcccctttgg
2341 ccggaacgaa cttctctccc ctctaaagga cagtgatgag atcaggtctc tctgggtcaa
2401 aatcgacctg accctcctgt ccaggatccc agaacacctg ccccaggagc caggggtatt
2461 gagcgcccct gccaccaagg actctgagag cgcaccgccc agccacacct cggacacacc
2521 tgcagaaaag gctttgccaa aatccaagag gaaacgcaag tgtgacaacg aagacgacta
2581 cagggagatc aagaagtccc agggagagaa agacagctct tcaagactgg ccacctccac
2641 cagtaatact ttgtctgcaa accactgcaa catgaacatc aacagtgtgg caataccaat
2701 aaataaaaat gaaaaaatgc ttcggtcgcc catctcaccc ctctctgatg catctaaaca
2761 caaatacacc agcgaggact taacttcttc cagccgacct aatggcaaca gtttgtttac
2821 ttcagcctct tccagcaaaa agcctaaggc cgacagccag ctgcagcctc acggcggaga
2881 cctcacgaaa gcagctcaca acaattctga aaacattccc ctccacaagt cacggccgca
2941 gacgaagccg tggtctccag gctccaacgg ccacagggac tgcaagaggc agaaacttgt
3001 cttcgatgat atgcctcgca gtgccgatta ttttatgcaa gaagctaaac gaatgaagca
3061 taaagcagat gcaatggtgg aaaagtttgg aaaggctttg aactatgctg aagcagcatt
3121 gtcgtttatc gagtgtggaa atgcaatgga acaaggcccc atggaatcca aatctcctta
3181 tacgatgtat tcagaaacag tagagctcat caggtatgct atgagactaa aaacccactc
3241 aggccccaat gccacaccag aagacaaaca actggctgca ttatgttacc gatgcctggc
3301 cctcctgtac tggcggatgt ttcgactcaa aagggaccac gctgtaaagt attcaaaagc
3361 actaatcgac tatttcaaga actcatctaa agccgcccaa gccccatctc cgtggggggc
3421 cagtggaaag agcactggaa ccccatcccc catgtctccc aacccctctc ccgccagctc
3481 cgtggggtct cagggcagcc tctccaacgc cagcgccctg tccccgtcga ccatcgtcag
3541 catcccacag cgcatccacc agatggcggc caaccacgtc agcatcacca acagcatcct
3601 gcacagctac gactactggg agatggccga caacctggcc aaggaaaacc gagaattctt
3661 caacgacctg gatctgctca tggggccggt caccctgcac agcagcatgg agcacctggt
3721 ccagtactcc caacagggcc tgcactggct gcggaacagc gcccacctgt catagggacc
3781 tcaccctggg gccagagtgg gctctggtct ccacaga
//