LOCUS BC136456 3784 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens integrin, alpha 6, mRNA (cDNA clone MGC:168068
IMAGE:9020445), complete cds.
ACCESSION BC136456
VERSION BC136456.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3784)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3784)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 670 Row: i Column: 19.
FEATURES Location/Qualifiers
source 1..3784
/db_xref="H-InvDB:HIT000500474"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:168068 IMAGE:9020445"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_311"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: GGAGCCAG"
gene 1..3784
/gene="ITGA6"
/gene_synonym="CD49f"
/gene_synonym="ITGA6B"
/gene_synonym="VLA-6"
/db_xref="GeneID:3655"
/db_xref="HGNC:HGNC:6142"
/db_xref="MIM:147556"
CDS 109..3330
/gene="ITGA6"
/gene_synonym="CD49f"
/gene_synonym="ITGA6B"
/gene_synonym="VLA-6"
/codon_start=1
/product="integrin, alpha 6"
/protein_id="AAI36457.1"
/db_xref="GeneID:3655"
/db_xref="HGNC:HGNC:6142"
/db_xref="MIM:147556"
/translation="MAAAGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLF
GFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARGPCTRIEFDND
ADPTSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQN
LRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVR
VEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITF
VSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIV
IGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRLNGTKDSMFGITVKNIGDINQDGY
PDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGISPYFGYSIAGNMDLDRNSYPDV
AVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGICLQVKSCFEYTAN
PAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEET
LWLQDNIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKE
GCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSP
SNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELG
NPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIELLLS
VSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWP
KEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRK
FSLFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLD
ILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLA
LLVFILWKCGFFKRNKKDHYDATYHKAEIHAQPSDKERLTSDA"
BASE COUNT 1109 a 782 c 917 g 976 t
ORIGIN
1 agaggaggcg aaggtggctg cggtagcagc agcgcggcag cctcggaccc agcccggagc
61 gcagggcggc cgctgcaggt ccccgctccc ctccccgtgc gtccgcccat ggccgccgcc
121 gggcagctgt gcttgctcta cctgtcggcg gggctcctgt cccggctcgg cgcagccttc
181 aacttggaca ctcgggagga caacgtgatc cggaaatatg gagaccccgg gagcctcttc
241 ggcttctcgc tggccatgca ctggcaactg cagcccgagg acaagcggct gttgctcgtg
301 ggggccccgc gggcagaagc gcttccactg cagagagcca acagaacggg agggctgtac
361 agctgcgaca tcaccgcccg ggggccatgc acgcggatcg agtttgataa cgatgctgac
421 cccacgtcag aaagcaagga agatcagtgg atgggggtca ccgtccagag ccaaggtcca
481 gggggcaagg tcgtgacatg tgctcaccga tatgaaaaaa ggcagcatgt taatacgaag
541 caggaatccc gagacatctt tgggcggtgt tatgtcctga gtcagaatct caggattgaa
601 gacgatatgg atgggggaga ttggagcttt tgtgatgggc gattgagagg ccatgagaaa
661 tttggctctt gccagcaagg tgtagcagct acttttacta aagactttca ttacattgta
721 tttggagccc cgggtactta taactggaaa gggattgttc gtgtagagca aaagaataac
781 actttttttg acatgaacat ctttgaagat gggccttatg aagttggtgg agagactgag
841 catgatgaaa gtctcgttcc tgttcctgct aacagttact taggtttttc tttggactca
901 gggaaaggta ttgtttctaa agatgagatc acttttgtat ctggtgctcc cagagccaat
961 cacagtggag ccgtggtttt gctgaagaga gacatgaagt ctgcacatct cctccctgag
1021 cacatattcg atggagaagg tctggcctct tcatttggct atgatgtggc ggtggtggac
1081 ctcaacaagg atgggtggca agatatagtt attggagccc cacagtattt tgatagagat
1141 ggagaagttg gaggtgcagt gtatgtctac atgaaccagc aaggcagatg gaataatgtg
1201 aagccaattc gtcttaatgg aaccaaagat tctatgtttg gcattacagt aaaaaatatt
1261 ggagatatta atcaagatgg ctacccagat attgcagttg gagctccgta tgatgacttg
1321 ggaaaggttt ttatctatca tggatctgca aatggaataa ataccaaacc aacacaggtt
1381 ctcaagggta tatcacctta ttttggatat tcaattgctg gaaacatgga ccttgatcga
1441 aattcctacc ctgatgttgc tgttggttcc ctctcagatt cagtaactat tttcagatcc
1501 cggcctgtga ttaatattca gaaaaccatc acagtaactc ctaacagaat tgacctccgc
1561 cagaaaacag cgtgtggggc gcctagtggg atatgcctcc aggttaaatc ctgttttgaa
1621 tatactgcta accccgctgg ttataatcct tcaatatcaa ttgtgggcac acttgaagct
1681 gaaaaagaaa gaagaaaatc tgggctatcc tcaagagttc agtttcgaaa ccaaggttct
1741 gagcccaaat atactcaaga actaactctg aagaggcaga aacagaaagt gtgcatggag
1801 gaaaccctgt ggctacagga taatatcaga gataaactgc gtcccattcc cataactgcc
1861 tcagtggaga tccaagagcc aagctctcgt aggcgagtga attcacttcc agaagttctt
1921 ccaattctga attcagatga acccaagaca gctcatattg atgttcactt cttaaaagag
1981 ggatgtggag acgacaatgt atgtaacagc aaccttaaac tagaatataa attttgcacc
2041 cgagaaggaa atcaagacaa attttcttat ttaccaattc aaaaaggtgt accagaacta
2101 gttctaaaag atcagaagga tattgcttta gaaataacag tgacaaacag cccttccaac
2161 ccaaggaatc ccacaaaaga tggcgatgat gcccatgagg ctaaactgat tgcaacgttt
2221 ccagacactt taacctattc tgcatataga gaactgaggg ctttccctga gaaacagttg
2281 agttgtgttg ccaaccagaa tggctcgcaa gctgactgtg agctcggaaa tccttttaaa
2341 agaaattcaa atgtcacttt ttatttggtt ttaagtacaa ctgaagtcac ctttgacacc
2401 ccagatctgg atattaatct gaagttagaa acaacaagca atcaagataa tttggctcca
2461 attacagcta aagcaaaagt ggttattgaa ctgcttttat cggtctcggg agttgctaaa
2521 ccttcccagg tgtattttgg aggtacagtt gttggcgagc aagctatgaa atctgaagat
2581 gaagtgggaa gtttaataga gtatgaattc agggtaataa acttaggtaa acctcttaca
2641 aacctcggca cagcaacctt gaacattcag tggccaaaag aaattagcaa tgggaaatgg
2701 ttgctttatt tggtgaaagt agaatccaaa ggattggaaa aggtaacttg tgagccacaa
2761 aaggagataa actccctgaa cctaacggag tctcacaact caagaaagaa acgggaaatt
2821 actgaaaaac agatagatga taacagaaaa ttttctttat ttgctgaaag aaaataccag
2881 actcttaact gtagcgtgaa cgtgaactgt gtgaacatca gatgcccgct gcgggggctg
2941 gacagcaagg cgtctcttat tttgcgctcg aggttatgga acagcacatt tctagaggaa
3001 tattccaaac tgaactactt ggacattctc atgcgagcct tcattgatgt gactgctgct
3061 gccgaaaata tcaggctgcc aaatgcaggc actcaggttc gagtgactgt gtttccctca
3121 aagactgtag ctcagtattc gggagtacct tggtggatca tcctagtggc tattctcgct
3181 gggatcttga tgcttgcttt attagtgttt atactatgga agtgtggttt cttcaagaga
3241 aataagaaag atcattatga tgccacatat cacaaggctg agatccatgc tcagccatct
3301 gataaagaga ggcttacttc tgatgcatag tattgatcta cttctgtaat tgtgtggatt
3361 ctttaaacgc tctaggtacg atgacagtgt tccccgatac catgctgtaa ggatccggaa
3421 agaagagcga gagatcaaag atgaaaagta tattgataac cttgaaaaaa aacagtggat
3481 cacaaagtgg aacgaaaatg aaagctactc atagcggggg cctaaaaaaa aaaatgcttc
3541 acagtaccca aactgctttt tccaactcag aaattcaatt tggatttaaa agcctgctca
3601 atccctgagg actgatttca gagtgactac acacagtacg aacctacagt tttaactgtg
3661 gatattgtta cgtagcctaa ggctcctgtt ttgcacagcc aaatttaaaa ctgttggaat
3721 ggatttttct ttaactgccg taatttaact ttctgggttg cctttgtttt tggcgtggct
3781 gact
//