LOCUS BC108255 2403 bp mRNA linear HUM 07-AUG-2008
DEFINITION Homo sapiens excision repair cross-complementing rodent repair
deficiency, complementation group 2, mRNA (cDNA clone MGC:102762
IMAGE:6044425), complete cds.
ACCESSION BC108255
VERSION BC108255.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2403)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2403)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 232 Row: b Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40068510.
FEATURES Location/Qualifiers
source 1..2403
/db_xref="H-InvDB:HIT000338997"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:102762 IMAGE:6044425"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2403
/gene="ERCC2"
/gene_synonym="COFS2"
/gene_synonym="EM9"
/gene_synonym="TTD"
/db_xref="GeneID:2068"
/db_xref="HGNC:HGNC:3434"
/db_xref="MIM:126340"
CDS 11..2293
/gene="ERCC2"
/gene_synonym="COFS2"
/gene_synonym="EM9"
/gene_synonym="TTD"
/codon_start=1
/product="excision repair cross-complementing rodent
repair deficiency, complementation group 2"
/protein_id="AAI08256.1"
/db_xref="GeneID:2068"
/db_xref="HGNC:HGNC:3434"
/db_xref="MIM:126340"
/translation="MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPS
GTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKL
PFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEE
FDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIA
DLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKET
DEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLR
RLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLA
DFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFER
FQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKF
ETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKL
LFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVP
YVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADK
RFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLS
LEQLESEETLKRIEQIAQQL"
BASE COUNT 549 a 724 c 678 g 452 t
ORIGIN
1 ggccggcgcc atgaagctca acgtggacgg gctcctggtc tacttcccgt acgactacat
61 ctaccccgag cagttctcct acatgcggga gctcaaacgc acgctggacg ccaagggtca
121 tggagtcctg gagatgccct caggcaccgg gaagacagta tccctgttgg ccctgatcat
181 ggcataccag agagcatatc cgctggaggt gaccaaactc atctactgct caagaactgt
241 gccagagatt gagaaggtga ttgaagagct tcgaaagttg ctcaacttct atgagaagca
301 ggagggcgag aagctgccgt ttctgggact ggctctgagc tcccgcaaaa acttgtgtat
361 tcaccctgag gtgacacccc tgcgctttgg gaaggacgtc gatgggaaat gccacagcct
421 cacagcctcc tatgtgcggg cgcagtacca gcatgacacc agcctgcccc actgccgatt
481 ctatgaggaa tttgatgccc atgggcgtga ggtgcccctc cccgctggca tctacaacct
541 ggatgacctg aaggccctgg ggcggcgcca gggctggtgc ccatacttcc ttgctcgata
601 ctcaatcctg catgccaatg tggtggttta tagctaccac tacctcctgg accccaagat
661 tgcagacctg gtgtccaagg aactggcccg caaggccgtc gtggtcttcg acgaggccca
721 caacattgac aacgtctgca tcgactccat gagcgtcaac ctcacccgcc ggacccttga
781 ccggtgccag ggcaacctgg agaccctgca gaagacggtg ctcaggatca aagagacaga
841 cgagcagcgc ctgcgggacg agtaccggcg tctggtggag gggctgcggg aggccagcgc
901 cgcccgggag acggacgccc acctggccaa ccccgtgctg cccgacgaag tgctgcagga
961 ggcagtgcct ggctccatcc gcacggccga gcatttcctg ggcttcctga ggcggctgct
1021 ggagtacgtg aagtggcggc tgcgtgtgca gcatgtggtg caggagagcc cgcccgcctt
1081 cctgagcggc ctggcccagc gcgtgtgcat ccagcgcaag cccctcagat tctgtgctga
1141 acgcctccgg tccctgctgc atactctgga gatcaccgac cttgctgact tctccccgct
1201 caccctcctt gctaactttg ccacccttgt cagcacctac gccaaaggct tcaccatcat
1261 catcgagccc tttgacgaca gaaccccgac cattgccaac cccatcctgc acttcagctg
1321 catggacgcc tcgctggcca tcaaacccgt atttgagcgt ttccagtctg tcatcatcac
1381 atctgggaca ctgtccccgc tggacatcta ccccaagatc ctggacttcc accccgtcac
1441 catggcaacc ttcaccatga cgctggcacg ggtctgcctc tgccctatga tcatcggccg
1501 tggcaatgac caggtggcca tcagctccaa atttgagacc cgggaggata ttgctgtgat
1561 ccggaactat gggaacctcc tgctggagat gtccgctgtg gtccctgatg gcatcgtggc
1621 cttcttcacc agctaccagt acatggagag caccgtggcc tcctggtatg agcaggggat
1681 ccttgagaac atccagagga acaagctgct ctttattgag acccaggatg gtgccgaaac
1741 cagtgtcgcc ctggagaagt accaggaggc ctgcgagaat ggccgcgggg ccatcctgct
1801 gtcagtggcc cggggcaaag tgtccgaggg aatcgacttt gtgcaccact acgggcgggc
1861 cgtcatcatg tttggcgtcc cctacgtcta cacacagagc cgcattctca aggcgcggct
1921 ggaatacctg cgggaccagt tccagattcg tgagaatgac tttcttacct tcgatgccat
1981 gcgccacgcg gcccagtgtg tgggtcgggc catcaggggc aagacggact acggcctcat
2041 ggtctttgcc gacaagcggt ttgcccgtgg ggacaagcgg gggaagctgc cccgctggat
2101 ccaggagcac ctcacagatg ccaacctcaa cctgaccgtg gacgagggtg tccaggtggc
2161 caagtacttc ctgcggcaga tggcacagcc cttccaccgg gaggatcagc tgggcctgtc
2221 cctgctcagc ctggagcagc tagaatcaga ggagacgctg aagaggatag agcagattgc
2281 tcagcagctc tgagtggggc gggtggggcc ataaacggtt cctggtgaaa aaaaaaaaaa
2341 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2401 aaa
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