LOCUS BC073151 4837 bp mRNA linear HUM 24-JUL-2006
DEFINITION Homo sapiens pleckstrin and Sec7 domain containing 4, mRNA (cDNA
clone MGC:87975 IMAGE:5757431), complete cds.
ACCESSION BC073151
VERSION BC073151.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4837)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4837)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 174 Row: d Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 56788369.
FEATURES Location/Qualifiers
source 1..4837
/db_xref="H-InvDB:HIT000264946"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87975 IMAGE:5757431"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4837
/gene="PSD4"
/gene_synonym="EFA6B"
/gene_synonym="TIC"
/db_xref="GeneID:23550"
/db_xref="HGNC:HGNC:19096"
CDS 146..3316
/gene="PSD4"
/gene_synonym="EFA6B"
/gene_synonym="TIC"
/codon_start=1
/product="pleckstrin and Sec7 domain containing 4"
/protein_id="AAH73151.1"
/db_xref="GeneID:23550"
/db_xref="HGNC:HGNC:19096"
/translation="MMGDYRLPDHPQPMEILNLYLGDSLEPHPGECPRETCSHEDPPE
PFEEQTWATDPPEPTRQNVPPWGSGVELTHLGSWVHQDGLEPCQEQTRATDPPESTRQ
DAPPWGSGVELTHLGSPSAQREHRQNTASPGSPVNSHLPGSPKQNRSTSTQVVFWAGI
LQAQMCVLDLEEELEKTEGLKAGLKCCLPTPPVDLPGDTGLHSSPPENEDSGEDSSEP
EGEGQAWLREGTPDSSPQWGAEEESMFFSNPLFLASPCSENSASGECFSWAASDSHAG
VRTGPESPATLEPPLPEDTVLWELESEPDLGDGAAISGHCTPPFPVPIYKPHSICWAS
VAAAEGAPAAPPGHGESEGDRLGPAPSAAPCVDEALTWESGCVGSDLGPAAHPVQPWA
SLSPEGWQRGGPFWPQVTLNSQDRDEREGGHPQESLPCTLAPCPWRSPASSPEPSSPE
SESRGPGPRPSPASSQEGSPQLQHHSSGILPKWTLDASQSSLLETDGEQPSSLKKKEA
GEAPKPGEEVKSEGTARPAETGDVQPDIHLTSAEHENLRTPMNSSWLPGSPMPQAQSP
EEGQRPPAGDKLANGVRNNKVAWNLASRLYRLEGFRKSEVAAYLQKNNDFSRAVAEEY
LSFFQFGGQSLDRALRSFLQALVLSGETQERERILYQFSRRFHHCNPGIFPSVDSVHT
LTCAIMLLNTDLHGQNIGKSMSCQEFITNLNGLRDGGNFPKELLKALYWSIRSEKLEW
AVDEEDTARPEKAQPSLPAGKMSKPFLQLAQDPTVPTYKQGILARKMHQDADGKKTPW
GKRGWKMFHTLLRGMVLYFLKQGEDHCLEGESLVGQMVDEPVGVHHSLATPATHYTKK
PHVFQLRTADWRLYLFQAPTAKEMSSWIARINLAAATHSAPPFPAAVGSQRRFVRPIL
PVGPAQSSLEEQHRSHENCLDAAADDLLDLQRNLPERRGRGRELEEHRLRKEYLEYEK
TRYETYVQLLVARLHCPSDALDLWEEQLGREAGGTREPKLSLKKSHSSPSLHQDEAPT
TAKVKRNISERRTYRKIIPKRNRNQL"
BASE COUNT 1041 a 1470 c 1433 g 893 t
ORIGIN
1 caggccaagc catccattct tgggtccttt ggagggtaga tatggattcc cagtttctcc
61 agcggccagt gctcccccta gtccacacag tgagaccgtg aaagcagatg ctccggggca
121 ctcctgggca gcttttgctc agtggatgat gggtgactac agactccctg accaccccca
181 gcccatggaa attctcaacc tgtacttggg agacagcctg gagccccacc caggagagtg
241 cccaagggaa acgtgcagcc atgaggatcc accggagcct ttcgaggagc aaacctgggc
301 cactgaccct cctgaaccta ccagacaaaa tgttcctccc tggggctccg gtgtggagct
361 cacacacctg gggagctggg tccatcagga cgggctggag ccttgccagg agcaaacccg
421 ggccactgac cctcctgaat ctaccagaca agatgctcct ccctggggct ccggtgtgga
481 gctcacacac ctggggagcc cctctgccca gagggagcac aggcagaaca cagcatcacc
541 agggtcacca gtgaacagcc atctaccggg gagcccaaag cagaaccgga gcacgtccac
601 acaggtagtg ttctgggcag gcatcctgca ggcccagatg tgtgtcctag acctggagga
661 ggagctggag aagacggaag ggctcaaggc tgggctgaaa tgctgtctcc ccacgccccc
721 tgtggacctc cccggggaca cgggcctgca ctccagccca cctgagaatg aagactcagg
781 ggaagacagc agcgagcctg agggagaggg ccaggcatgg ctgagagagg gaaccccaga
841 ctcttcccca cagtggggag ctgaggagga gagcatgttc ttcagcaacc ccctcttcct
901 ggcgagtcct tgctcagaga acagtgcttc tggagagtgc ttttcctggg cggcttcaga
961 ctcccatgca ggtgtgagga ctggacctga gagcccagcg actctggagc ctcccctccc
1021 agaagacaca gtgctgtggg agctggaaag tgagccagat ttgggggacg gcgctgctat
1081 cagtgggcat tgtacccctc cattccctgt gcccatctat aaaccacact ccatctgctg
1141 ggcctcagtg gctgccgctg agggggctcc tgcagcacct cctggtcacg gggagagtga
1201 gggagatagg cttggtcctg ctccatctgc agcaccgtgt gtggacgaag cattgacctg
1261 ggaatcagga tgtgtcggat ctgatcttgg ccctgctgca catcctgtgc aaccttgggc
1321 ctctctcagc cctgagggct ggcagagagg aggtcctttt tggccccagg tgactcttaa
1381 ctcccaggac agagatgaga gggagggtgg gcacccccag gaatctcttc cctgcacctt
1441 ggccccctgc ccctggagga gcccagcttc ttctccagag cctagcagcc cagaatctga
1501 gagcagaggc cctggtccca ggcccagccc tgcatcgtcc caggagggca gcccgcagct
1561 tcaacaccac agctcaggca ttttgcccaa gtggacacta gatgcttcac agtcttcact
1621 cttggagacg gatggggaac agccaagttc cttgaagaaa aaggaggcag gggaggcccc
1681 aaaaccaggc gaggaagtaa agagtgaagg aacagccagg cctgcagaga ctggagacgt
1741 ccagcctgac attcacctga cttctgcaga acatgagaat ctgaggacac cgatgaactc
1801 ttcttggctt cctgggagcc ctatgcccca agcacagtcc ccagaggaag gccagagacc
1861 accagctgga gacaagctag ctaatggcgt caggaacaac aaggtagcct ggaacttggc
1921 ctcacgcctc tatcgcctgg agggcttccg gaagtctgaa gtggctgcct acctgcagaa
1981 gaacaatgac tttagcaggg ctgtggctga ggagtacctg tccttcttcc agtttggagg
2041 ccagagtctg gaccgagccc tccggagctt cctccaggcc ttggtgctca gtggggagac
2101 tcaggaacgg gagcgaatcc tctaccagtt ctccagacgc ttccaccatt gcaatccggg
2161 gatcttcccc tcagtagatt ctgtacacac cttgacatgt gcaatcatgc tgcttaacac
2221 ggacctgcat ggacagaaca ttgggaagag catgagctgc caggaattca taaccaacct
2281 gaatgggctg agggatggcg ggaacttccc caaggagctg ctgaaggccc tctactggtc
2341 tatccgcagc gagaagctcg agtgggccgt ggatgaagaa gacacagcca gacctgagaa
2401 ggcccagccg tccctgccag ctggcaagat gagcaagccc ttccttcagc tggctcagga
2461 tcccacagtg cccacctaca agcagggcat cctggctcgg aaaatgcatc aagatgcaga
2521 cggcaagaag acgccatggg gcaagcgtgg ctggaagatg ttccacacct tactgcgagg
2581 gatggttctc tacttcctga agcagggaga agaccactgt ctggaggggg agagcttggt
2641 ggggcagatg gtggatgagc ccgtgggggt gcaccactcg ctggccaccc ccgccacgca
2701 ttacaccaag aagccgcacg tcttccagct gcgcacggct gactggcgcc tctacctctt
2761 ccaggcaccc actgccaagg agatgagctc ctggatcgcg cgcatcaact tggctgcggc
2821 cacgcactcc gcgccgccct tccccgccgc tgtgggctcc cagcgcagat tcgtgcggcc
2881 catcctgccc gtgggccccg cccagagctc cctggaggag cagcatcgat cccacgagaa
2941 ctgcctggac gctgccgcgg acgacctgct ggatctacag aggaacctgc cggagcggcg
3001 gggccgtggc cgcgagctgg aggagcaccg cctgcggaag gagtacctgg agtacgagaa
3061 aacccgctac gagacctacg tgcagctgct ggtggcccgc ctgcactgcc cctctgatgc
3121 tctggacctg tgggaggagc agctggggag ggaagctgga ggcactcggg agcccaagct
3181 cagcctgaag aagtcccact cgagcccgtc cctgcaccag gatgaggctc ccaccacggc
3241 caaggtgaag cgcaacatct cagagcgcag aacctaccgg aagatcatcc ctaagcggaa
3301 ccgcaatcag ctgtgaagcc agcaccacct cagagacact gttccctgct ccagggtaga
3361 cctgagatga acctccctgg aggagactta tttcaatgag tccaccatga cggatgaggc
3421 acctcctttc cctgctgaag gacaaacctt gtttccctgt ggccctcatt cttgtgctcc
3481 ctgaagcttt cctaatattg ctgtgctccc caccaccccc atggcagtcc ctccgcagcc
3541 ccagtccctg gccacgccca agggaagagg gaggtgagga cttgactttc ctcccagagc
3601 tcagcccatg tcaccctcca ggccccagaa tccagagtgg cctcatttcc tagacttgct
3661 gagaactcag cacttgtttg agaaccagtg cttatgtggt gtgcccttgg cttctggggg
3721 agagcttggg gcagcagagg cccctgggca gcccagccag gggagccaca gccccgagga
3781 tggtcttgct ctgggaatta ggtgaccttc ctggggaggc cccaggagag tgaatcaggg
3841 actcttgaga aattcctaac cagcctcctg tgacccaggg agcagggtcg ctaaggtcct
3901 gcccactgag gggacagcct tctgggcagg gacctcgggg ggcttcaagg gctctgcacg
3961 gctgtggggc cctgtgcctt tgtctccttg tgtctccttt cccccgaagt agatgaaaca
4021 gtctcacata cccaactgct catcaacaga gcagagctga tggcatgagt gagggctggg
4081 cggggtgggg cctccagagc tttgcaggga accctggaac cctaggaaca aggagccttt
4141 gttccaacag agcagagaag gaggttctct atgttcagac cactggagag gatagagagg
4201 taaaaggtgg cgacagtttc ccttaggggt ctgcctggca ggagccacag ctcaggagag
4261 ttgtgaggga tgggacggag gctggcgacc aggcgaggcc taggccaggc tcgggagact
4321 tttctgtgct cctttctaca catgccttaa accttccttc ctgtggggtg cctggacccc
4381 ttccccatct ctggcagctc agagggtctc tgctgctctc ccctgggaaa tcccctcatc
4441 ctgccctctg gctgcctccc agctgggctt gttctctgag ggaggttccg gagactcatg
4501 gacttggggc tctgcctgta ggaaggaggc tgggccggag ggaccagcca ccattgtctc
4561 tgttcagcca agtgtgcaag taggctgccc gccaagaggg ggcctctgct acccgctgct
4621 gcctgccggc tgacacactg cctccccagc cttcctgcta ggccaccctc ctcccttccc
4681 atgcttgtaa ccagctctgg ggcttgcacc tccacaaagt aaggttggcc cttggaggcc
4741 atgtttgggt ctccggccag ggcctagggc taggccatgc acccaatggg tgcacaataa
4801 ataacaggtc aacaaaaaaa aaaaaaaaaa aaaaaaa
//