LOCUS BC070055 4746 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens guanylate binding protein 4, mRNA (cDNA clone
MGC:87193 IMAGE:30345441), complete cds.
ACCESSION BC070055
VERSION BC070055.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4746)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4746)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-MAY-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 168 Row: n Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 31377633.
FEATURES Location/Qualifiers
source 1..4746
/db_xref="H-InvDB:HIT000264013"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87193 IMAGE:30345441"
/tissue_type="Placenta, normal"
/clone_lib="NIH_MGC_147"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4746
/gene="GBP4"
/gene_synonym="Mpa2"
/db_xref="GeneID:115361"
/db_xref="HGNC:HGNC:20480"
CDS 54..1976
/gene="GBP4"
/gene_synonym="Mpa2"
/codon_start=1
/product="guanylate binding protein 4"
/protein_id="AAH70055.1"
/db_xref="GeneID:115361"
/db_xref="HGNC:HGNC:20480"
/translation="MGERTLHAAVPTPGYPESESIMMAPICLVENQEEQLTVNSKALE
ILDKISQPVVVVAIVGLYRTGKSYLMNRLAGKRNGFPLGSTVQSETKGIWMWCVPHLS
KPNHTLVLLDTEGLGDVEKSNPKNDSWIFALAVLLSSSFVYNSVSTINHQALEQLHYV
TELAELIRAKSCPRPDEAEDSSEFASFFPDFIWTVRDFTLELKLDGNPITEDEYLENA
LKLIPGKNPKIQNSNMPRECIRHFFRKRKCFVFDRPTNDKQYLNHMDEVPEENLERHF
LMQSDNFCSYIFTHAKTKTLRKGIIVTGKRLGTLVVTYVDAINSGAVPCLENAVTALA
QLENPAAVQRAADHYSQQMAQQLRLPTDTLQELLDVHAACEREAIAVFMEHSFKDENH
EFQKKLVDTIEKKKGDFVLQNEEASAKYCQAELKRLSEHLTESILRGIFSVPGGHNLY
LEEKKQVEWDYKLVPRKGVKANEVLQNFLQSQVVVEESILQSDKALTAGEKSIAAERA
MKEAAEKEQELLREKQKEQQQMMEAQERSFQEYMAQMEKKLEEERENLLREHERLLKH
KLKVQEEMLKEEFQKKSEQLNKEINQLKEKIESTKNEQLRLLKILDMASNIMIVTLPG
ASKLLGVGTKYLGSRI"
BASE COUNT 1333 a 957 c 1063 g 1393 t
ORIGIN
1 agcttctaag aacagtccgt ttctcgagga tccaggcgca ggaggacaga gcaatgggtg
61 agagaactct tcacgctgca gtgcccacac caggttatcc agaatctgaa tccatcatga
121 tggcccccat ttgtctagtg gaaaaccagg aagagcagct gacagtgaat tcaaaggcat
181 tagagattct tgacaagatt tctcagcccg tggtggtggt ggccattgta gggctatacc
241 gcacaggaaa atcctatctc atgaatcgtc ttgcaggaaa gcgcaatggc ttccctctgg
301 gctccacggt gcagtctgaa actaagggca tctggatgtg gtgtgtgccc cacctctcta
361 agccaaacca caccctggtc cttctggaca ccgagggcct gggcgatgta gaaaagagta
421 accctaagaa tgactcgtgg atctttgccc tggctgtgct tctaagcagc agctttgtct
481 ataacagcgt gagcaccatc aaccaccagg ccctggagca gctgcactat gtgactgagc
541 tagcagagct aatcagggca aaatcctgcc ccagacctga tgaagctgag gactccagcg
601 agtttgcgag tttctttcca gactttattt ggactgttcg ggattttacc ctggagctaa
661 agttagatgg aaaccccatc acagaagatg agtacctgga gaatgccttg aagctgattc
721 caggcaagaa tcccaaaatt caaaattcaa acatgcctag agagtgtatc aggcatttct
781 tccgaaaacg gaagtgcttt gtctttgacc ggcctacaaa tgacaagcaa tatttaaatc
841 atatggacga agtgccagaa gaaaatctgg aaaggcattt ccttatgcaa tcagacaact
901 tctgttctta tatcttcacc catgcaaaga ccaagaccct gagaaaggga atcattgtca
961 ctggaaagcg gctggggact ctggtggtga cttatgtaga tgccatcaac agtggagcag
1021 taccttgtct ggagaatgca gtgacagcac tggcccagct tgagaaccca gcggctgtgc
1081 agagggcagc cgaccactat agccagcaga tggcccagca actgaggctc cccacagaca
1141 cgctccagga gctgctggac gtgcatgcag cctgtgagag ggaagccatt gcagtcttca
1201 tggagcactc cttcaaggat gaaaaccatg aattccagaa gaagcttgtg gacaccatag
1261 agaaaaagaa gggagacttt gtgctgcaga atgaagaggc atctgccaaa tattgccagg
1321 ctgagcttaa gcggctttca gagcacctga cagaaagcat tttgagagga attttctctg
1381 ttcctggagg acacaatctc tacttagaag aaaagaaaca ggttgagtgg gactataagc
1441 tagtgcccag aaaaggagtt aaggcaaacg aggtcctcca gaacttcctg cagtcacagg
1501 tggttgtaga ggaatccatc ctgcagtcag acaaagccct cactgctgga gagaagtcca
1561 tagcagcgga gcgggccatg aaggaagcag ctgagaagga acaggagctg ctaagagaaa
1621 aacagaagga gcagcagcaa atgatggagg ctcaagagag aagcttccag gaatacatgg
1681 cccaaatgga gaagaagttg gaggaggaaa gggaaaacct tctcagagag catgaaaggc
1741 tgctaaaaca caagctgaag gtacaagaag aaatgcttaa ggaagaattt caaaagaaat
1801 ctgagcagtt aaataaagag attaatcaac tgaaagaaaa aattgaaagc actaaaaatg
1861 aacagttaag gctcttaaag atccttgaca tggctagcaa cataatgatt gtcactctac
1921 ctggggcttc caagctactt ggagtaggga caaaatatct tggctcacgt atttaagagc
1981 ctgaatattc caggtaagaa aatataaaat gaggtttatt ttattttaat aacataacac
2041 tgttgctcat tttgtaagta tatgtgttat agcagtttca ttcaagaaaa gtttaaaatt
2101 aaaaagtgat tatcaaagaa tatcagggcc tgacatccac aaaaaacaaa cttaattttg
2161 attgaactaa taatttataa acatgggaaa caagtcagaa gtagtgacat tattcctaga
2221 aaagatttaa ggaaagcaaa aagacaactg gtaagattaa gaagccatta accatttgca
2281 atttatatta tagtcacaga aataatttca gttatgacta gctcttgccg attaatgaga
2341 agagagcagc tccacaattt ttaatttttt taacttttat tttagattca ggggtatatg
2401 tgcaggtttg ttacataggt aaactgcatg tcatgggggt ttggtgtgca gataatttta
2461 tcacacaatt attaatcata atacccaata ggtttttttc tgatcttctc cctcctccca
2521 acctacaccc tcaagtagac cccagtgtct cttgttctcc tctgagtatc catgtgttct
2581 ctttgtttgg cccccattta taagtgagaa catgtggtat ttgggtttct gttcctgtgt
2641 tagtttgctt atgataatgg cttccagctc catccatatt gctacagagg acatgatctt
2701 gttgtttttt atggctgcat agtattccat ggtgtttgta tataccacat tttcattatc
2761 cagcctatta ttaatgcaca tttaggttga ttccttatct ttgctattgt gaacagtgct
2821 gcaatggaca tacacgtgca tgtgccttta tggtacaatg atttatattt ccttgggata
2881 tgcattcctt tgggaataat gggattgctg agttgaatgg taattctgag ttctttgagg
2941 aatcaccaac ctgctttcca cagtggctaa actaatttac actcccacca acagtgtatg
3001 tgttccattt tctccacaac cttgccagca tctgttattt attgactttc tagtaacagc
3061 cattctgact ggtgtgagat ggtatgcatt tctgtagtga ttagtgatga tgagtgattt
3121 ttatatgctt tttaaatgca tatatgtctt cttttgaaat gtgttcatgt tctttgccca
3181 ctttcttttt aatggggttg cttgtttttc gcttgtaaat tttttgaagc ttcttataga
3241 ttctggatat tagatctttg ttggatgcat agttggcaaa tattttctac cattctgtag
3301 gttgtctgtt actttgttaa ttgtttcatt ttgttttgtt tttgtttttt gagacggggt
3361 ctcgctttga cacccaggct ggagtgcagt agcacaaaca tgggtcattg tagcctcaac
3421 ctcccaggct caagcagtcc tttcacctca gccccccaca tagctgggac tacaggtgct
3481 tacacccaag accagttaat tttttgtatt tgtttgtaga gatgtgtttt tccatgttgc
3541 ccaagctggt cttgaactac tgagctcaag caatctgcct gcttcagcct cccaaagtac
3601 tgggatttag gcatgagcca ccacatctgg ccaatagttt cttttgatgt gcagaagctc
3661 tttaatttaa ttagatctcc tttgtcagtt tttgtttttg ctgcaattgc ttatgttatc
3721 ttcatcatga aattttagcc aagtcttatg tccagaatgg tatttcttag gttatttttc
3781 agagttttta tagtttaatg ttttatattt aagtctttaa tccttcttaa gttgattttt
3841 gtatgcagag taagctgggg gcccagtttc aatcttctgc atatggctag ccagtaatcc
3901 cagcaccatt tattaaatgg ggacttcttt ccccattgct tgtttttgtc agctttgtcc
3961 aagatcagat gattgtaggt gtacagcatt atttctggac tctctgttat gttccattta
4021 tctgtgtgtc tgtttttcta ctaataccat gctgttttgg ttactgtagc tctgtagtat
4081 ggtttgaggt ttggtaactt gatgcctccc cttttgttct ttatgtttag gattgccttg
4141 gctaggctct tttttggttc catatgaatt ttaaagtagt ttctaattct gtgaagaatg
4201 tcattggtag tttgataggg atagcattga actatttgct caactcaaca ttttaggaat
4261 ttatttctgc tgtctagtgc tcaaaacttg cagctagaat tgagggaaga gagagacctt
4321 cttatattgt tttatattgt ttgatactca gtacctgttt taagaaaaaa caacaaggaa
4381 gtaaaaccaa agacaggcag cccagcgcca ggcccaaaac caggcctggg cctgcctggc
4441 ctaaacccag tagttaaaaa tcaactcatt gcctgtaatc ccagcacttt gggaggccga
4501 gacgggtgga tcacgaggtc aggagatcga gaccatcctg gctaacacgg tgaaaccccg
4561 tctctactaa aaatacaaaa attggccggg catggtggca cgcgcctgtg gtcccagcta
4621 cacgggaggc tgaggcagga gaatggcgtg aacccaggag gcggagcttg cagtgagtcg
4681 agatcgcgcc actgcactcc agcctgggcg acagagcgaa actccgtccc aaaaaaaaaa
4741 aaaaaa
//