LOCUS BC068532 3585 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens claudin 12, mRNA (cDNA clone MGC:87367 IMAGE:5294796),
complete cds.
ACCESSION BC068532
VERSION BC068532.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3585)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3585)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 168 Row: c Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 37537523.
FEATURES Location/Qualifiers
source 1..3585
/db_xref="H-InvDB:HIT000263089"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87367 IMAGE:5294796"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3585
/gene="CLDN12"
/db_xref="GeneID:9069"
/db_xref="HGNC:HGNC:2034"
CDS 226..960
/gene="CLDN12"
/codon_start=1
/product="claudin 12"
/protein_id="AAH68532.1"
/db_xref="GeneID:9069"
/db_xref="HGNC:HGNC:2034"
/translation="MGCRDVHAATVLSFLCGIASVAGLFAGTLLPNWRKLRLITFNRN
EKNLTVYTGLWVKCARYDGSSDCLMYDTTWYSSVDQLDLRVLQFALPLSMLIAMGALL
LCLIGMCNTAFRSSVPNIKLAKCLVNSAGCHLVAGLLFFLAGTVSLSPSIWVIFYNIH
LNKKFEPVFSFDYAVYVTIASAGGLFMTSLILFIWYCTCKSLPSPFWQPLYSHPPSMH
TYSQPYSARSRLSAIEIDIPVVSHTT"
BASE COUNT 1064 a 652 c 662 g 1207 t
ORIGIN
1 ggtgtacctc gctgggaacg cacttcctgg gacgctgaga gggagacgct ccaagaggct
61 cctcagtgtg ggcgagtaaa atgccctgcg tgtgagaagc aggctcagat tattgctact
121 ctgtattcag atcttcatgt gtctcttcta agctgaataa agctgttttg gaactgtcag
181 gtacctcaaa gctctgactg acagtactcc acaagcttgc ctgccatggg ctgtcgggat
241 gtccacgcag ccacagtcct ttccttcctg tgtggaatcg cctcagtagc aggcctcttt
301 gcagggactc tgcttcccaa ctggagaaaa ttacgattga tcacattcaa cagaaacgag
361 aagaacctga ctgtttacac aggcctgtgg gtgaaatgtg cccggtatga cgggagcagt
421 gactgcctga tgtacgacac tacttggtac tcatcagttg accagctgga cctgcgtgtc
481 ctccagtttg ccctacccct cagcatgctg atcgccatgg gtgccctgct gctctgcctg
541 attggaatgt gcaacactgc cttcaggtcc tcggtgccca acatcaaact ggccaagtgt
601 ctggtcaata gtgcaggttg ccacctggtg gctgggctgc tatttttcct ggcaggtact
661 gtgagcctct ccccatctat ctgggtcatc ttttataaca tccatctgaa caagaagttt
721 gagccagtct tttcatttga ctatgcagtg tatgtcacta ttgctagtgc tgggggcctg
781 tttatgactt cccttatact atttatttgg tattgtacat gcaaatcttt gccttctcct
841 ttctggcaac cattgtactc ccatccaccc agtatgcata cttactcaca gccctattca
901 gcacgctctc gcctctctgc cattgaaatt gacattccag tagtttcaca caccacttaa
961 tggggaaata gttaattgtt aaagaaaact tcttgtagcc tcacattccc cttgtgcaaa
1021 gagctctttt ggacctacat acattttcct ttgtttttga ccaatcaatg aagccaaatt
1081 tatatgtcct agtagaatga agtgctgcta gtttttatga gaagtatatt atattaaatg
1141 tgaatttttt aaattttgct tcttatactg gaaggaattt tagccttcat attgatatct
1201 aattaattat ttaagtggaa taggcctgca tcacaattga ggtaatgtag agcaacatgt
1261 taaagaatga tggttagcag aagctgttgt atacaatctt catgaaaatt tcagtgtgta
1321 tttttctttt tctataatac ctttaactgc aaagaaaagg cagtttcaaa tataagaaat
1381 ttatttcagg taagggtaat attttaatag tagtcaataa tctagcttaa ggctgtaact
1441 cttctatcgg ggctaattgt atgaataggt gtcagtatgt tgaagattac tttcttttgt
1501 gactttcttc tacctcatgc cactgtttaa aagtaaaacg tattttaatg atgttagaat
1561 aagactacca ttctaaatat cacctactta tgaataacat gtaataattt ttaacattaa
1621 tgattccata aattgtatta ttgggattag aatgtgcttt atgacaggtt agtgtttcct
1681 ctgaggcaga aaactctttt ttggagatat cttccatcaa gcagtactcg tgcccatata
1741 caatctctta gtggctagga gaaataaata aaagggccat aatggtttgt tctctttcag
1801 acataattta gtaggggaca agaagtctgt tcttcagtga gtacactaga gatttactct
1861 ggtgactgcc ttttgagtta tgggtgaagt aaggtatggc tttaccataa ccttgattca
1921 ttcacccttg attcatttct cgcccccgtc actgattatt tccttgagca tatatctctg
1981 cctaacactt tagtaggtgc tatagaggat acatgaaaag tatgagatct ggttccatcc
2041 agtaagacat tttaatagag aagatcaaaa tgttacctgg cagttgggga ataatctgac
2101 ttcgttggca gttggcctta acttcttaat cattgatcca ggaatatttc aaccagagac
2161 acaactttct ggcagacaga caaattgtac aacaccaaca atatcctgga ccttgaaatt
2221 ctgtttactt cagtccattg tatcctttaa ggcacctgtg ctagcctaga ttttgtaata
2281 acactgattt atgagaatgg acaaaagtgg tagggaaatt gttccctctc cacttctgaa
2341 agtatgatga tgtattaagg atggaggagt tattaaaaat gtctcttctg atgaggtaac
2401 aattagatga aaccatgtta aagctgagat gaacacttag aaattcaggg atattgggtc
2461 tttagcctta tgaatttgag ctgcttattt aattggtgta atttactaca tattagtact
2521 atattcgtaa ggatttttta ttaaccatta cagattttac aaacagctag ttatatggta
2581 aacagattat tatgcctttt tgcaattctg aatatgattc tagtatttgt gtagatgtat
2641 ttggtacttt ttcacctaat tccaacacta gtttatatat atagcgaata aatctagttg
2701 tataaatttt taaatgccgt cagtagaaag cacacaaggt tatgattttt ttaattactg
2761 gcttatgatt tctttcactt ctgatccttt tcctttttct cagatgtagc tgagtcttga
2821 tcattttaag acaacgatgg gtagaatttt gagattaatg ttaattttcc ctttttgtta
2881 atttcagtcc cctctcacta tgcttttgtc cagaaggatc aagaattcta ccatcccttg
2941 ggtctttgtg tataaacaat gttaaataaa ggtagactca gtctttaaga tattagacag
3001 tttttttagt ccatgggatt gtaaatataa acattaactt tcctataaga atattttggc
3061 tttgtaatct atagcctcaa attggtattt attatggatt cactagacaa acagctgttt
3121 ccttattgtc ttttttcttt agtgtttctg atttgctatc agtagctgtt tttaaagcca
3181 tccaaggaaa ataattattt acagtttttg aagtcacttt tgagccctca tcaagctctc
3241 attgtgatgg gagggatacc tttttgttgt taaaagccta ttattgttaa aggcctttta
3301 tggaaaccaa cttggaaaac aaccttaaat gtggatgtat cagatttggt ttatccagcc
3361 atgggagaga aaacaaacct aagtttactt tacttgtaca tatacactac aatggatagt
3421 atatttgctg taaactacaa tgtaaaacct caataaaagt gcgctgtact tcttaatgtt
3481 tattaaaaga tgtattttta caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3541 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//