LOCUS BC067418 1679 bp mRNA linear HUM 20-MAY-2005
DEFINITION Homo sapiens activin A receptor, type IIA, mRNA (cDNA clone
MGC:79238 IMAGE:7002205), complete cds.
ACCESSION BC067418
VERSION BC067418.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1679)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1679)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Narayan Bhat
cDNA Library Preparation: Bhat Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 172 Row: h Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 10862696.
FEATURES Location/Qualifiers
source 1..1679
/db_xref="H-InvDB:HIT000262576"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:79238 IMAGE:7002205"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_195"
/lab_host="DH10B"
/note="Vector: pDNR-Dual"
gene 1..1679
/gene="ACVR2A"
/gene_synonym="ACTRII"
/gene_synonym="type II"
/db_xref="GeneID:92"
/db_xref="MIM:102581"
CDS 87..1628
/gene="ACVR2A"
/gene_synonym="ACTRII"
/gene_synonym="type II"
/codon_start=1
/product="activin A receptor, type IIA, precursor"
/protein_id="AAH67418.1"
/db_xref="GeneID:92"
/db_xref="MIM:102581"
/translation="MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWEKDRTNQ
TGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYF
CCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWV
YRHHKMAYPPVLVPTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAV
KIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLS
DFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNL
TACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGL
VLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAG
MAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPP
KESSL"
BASE COUNT 488 a 326 c 409 g 456 t
ORIGIN
1 acaccaggag gtttgtctcc gaggaagacc cagggaactg gatatctagc gagaacttcc
61 tccggattcc ccggcgcctc gggaaaatgg gagctgctgc aaagttggcg tttgccgtct
121 ttcttatctc ctgttcttca ggtgctatac ttggtagatc agaaactcag gagtgtcttt
181 tctttaatgc taattgggaa aaagacagaa ccaatcaaac tggtgttgaa ccgtgttatg
241 gtgacaaaga taaacggcgg cattgttttg ctacctggaa gaatatttct ggttccattg
301 aaatagtgaa acaaggttgt tggctggatg atatcaactg ctatgacagg actgattgtg
361 tagaaaaaaa agacagccct gaagtatatt tttgttgctg tgagggcaat atgtgtaatg
421 aaaagttttc ttattttccg gagatggaag tcacacagcc cacttcaaat ccagttacac
481 ctaagccacc ctattacaac atcctgctct attccttggt gccacttatg ttaattgcgg
541 ggattgtcat ttgtgcattt tgggtgtaca ggcatcacaa gatggcctac cctcctgtac
601 ttgttccaac tcaagaccca ggaccacccc caccttctcc attactaggt ttgaaaccac
661 tgcagttatt agaagtgaaa gcaaggggaa gatttggttg tgtctggaaa gcccagttgc
721 ttaacgaata tgtggctgtc aaaatatttc caatacagga caaacagtca tggcaaaatg
781 aatacgaagt ctacagtttg cctggaatga agcatgagaa catattacag ttcattggtg
841 cagaaaaacg aggcaccagt gttgatgtgg atctttggct gatcacagca tttcatgaaa
901 agggttcact atcagacttt cttaaggcta atgtggtctc ttggaatgaa ctgtgtcata
961 ttgcagaaac catggctaga ggattggcat atttacatga ggatatacct ggcctaaaag
1021 atggccacaa acctgccata tctcacaggg acatcaaaag taaaaatgtg ctgttgaaaa
1081 acaacctgac agcttgcatt gctgactttg ggttggcctt aaaatttgag gctggcaagt
1141 ctgcaggcga tacccatgga caggttggta cccggaggta catggctcca gaggtattag
1201 agggtgctat aaacttccaa agggatgcat ttttgaggat agatatgtat gccatgggat
1261 tagtcctatg ggaactggct tctcgctgta ctgctgcaga tggacctgta gatgaataca
1321 tgttgccatt tgaggaggaa attggccagc atccatctct tgaagacatg caggaagttg
1381 ttgtgcataa aaaaaagagg cctgttttaa gagattattg gcagaaacat gctggaatgg
1441 caatgctctg tgaaaccatt gaagaatgtt gggatcacga cgcagaagcc aggttatcag
1501 ctggatgtgt aggtgaaaga attacccaga tgcagagact aacaaatatt attaccacag
1561 aggacattgt aacagtggtc acaatggtga caaatgttga ctttcctccc aaagaatcta
1621 gtctatgatg gttgcgccat ctgtgcacac taagaaatgg gactctgaac tggagctgc
//