LOCUS BC066841 3697 bp mRNA linear ROD 15-JUL-2006
DEFINITION Mus musculus CD274 antigen, mRNA (cDNA clone MGC:76638
IMAGE:30101931), complete cds.
ACCESSION BC066841
VERSION BC066841.1
KEYWORDS MGC.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 3697)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3697)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Angelo L. Vescovi (Institute for Stem Cell
Research, Italy)
cDNA Library Preparation: Yulan Piao and Minoru Ko (National
Institute on Aging, NIH: http://lgsun.grc.nia.nih.gov/cDNA/)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 144 Row: g Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 45433566.
FEATURES Location/Qualifiers
source 1..3697
/organism="Mus musculus"
/mol_type="mRNA"
/strain="CD1"
/db_xref="taxon:10090"
/clone="MGC:76638 IMAGE:30101931"
/tissue_type="Neural Stem Cell, (Differentiated), adult
mouse"
/clone_lib="NIA Mouse Neural Stem Cell (Differentiated)
cDNA Library (Long)"
/lab_host="DH10B"
/note="Vector: pSPORT1"
gene 1..3697
/gene="Cd274"
/gene_synonym="B7-H1"
/gene_synonym="PD-L1"
/gene_synonym="Pdcd1l1"
/db_xref="GeneID:60533"
/db_xref="MGI:MGI:1926446"
CDS 67..939
/gene="Cd274"
/gene_synonym="B7-H1"
/gene_synonym="PD-L1"
/gene_synonym="Pdcd1l1"
/codon_start=1
/product="CD274 antigen"
/protein_id="AAH66841.1"
/db_xref="GeneID:60533"
/db_xref="MGI:MGI:1926446"
/translation="MRIFAGIIFTACCHLLRAFTITAPKDLYVVEYGSNVTMECRFPV
ERELDLLALVVYWEKEDEQVIQFVAGEEDLKPQHSNFRGRASLPKDQLLKGNAALQIT
DVKLQDAGVYCCIISYGGADYKRITLKVNAPYRKINQRISVDPATSEHELICQAEGYP
EAEVIWTNSDHQPVSGKRSVTTSRTEGMLLNVTSSLRVNATANDVFYCTFWRSQPGQN
HTAELIIPELPATHPPQNRTHWVLLGSILLFLIVVSTVLLFLRKQVRMLDVEKCGVED
TSSKNRNDTQFEET"
BASE COUNT 1006 a 855 c 773 g 1063 t
ORIGIN
1 gcctcatgcc aggctgcact tgcacgtcgc gggccagtct cctcgcctgc agatagttcc
61 caaaacatga ggatatttgc tggcattata ttcacagcct gctgtcactt gctacgggcg
121 tttactatca cggctccaaa ggacttgtac gtggtggagt atggcagcaa cgtcacgatg
181 gagtgcagat tccctgtaga acgggagctg gacctgcttg cgttagtggt gtactgggaa
241 aaggaagatg agcaagtgat tcagtttgtg gcaggagagg aggaccttaa gcctcagcac
301 agcaacttca gggggagagc ctcgctgcca aaggaccagc ttttgaaggg aaatgctgcc
361 cttcagatca cagacgtcaa gctgcaggac gcaggcgttt actgctgcat aatcagctac
421 ggtggtgcgg actacaagcg aatcacgctg aaagtcaatg ccccataccg caaaatcaac
481 cagagaattt ccgtggatcc agccacttct gagcatgaac taatatgtca ggccgagggt
541 tatccagaag ctgaggtaat ctggacaaac agtgaccacc aacccgtgag tgggaagaga
601 agtgtcacca cttcccggac agaggggatg cttctcaatg tgaccagcag tctgagggtc
661 aacgccacag cgaatgatgt tttctactgt acgttttgga gatcacagcc agggcaaaac
721 cacacagcgg agctgatcat cccagaactg cctgcaacac atcctccaca gaacaggact
781 cactgggtgc ttctgggatc catcctgttg ttcctcattg tagtgtccac ggtcctcctc
841 ttcttgagaa aacaagtgag aatgctagat gtggagaaat gtggcgttga agatacaagc
901 tcaaaaaacc gaaatgatac acaattcgag gagacgtaag cagtgttgaa ccctctgatc
961 gtcgattggc agcttgtggt ctgtgaaaga aagggcccat gggacatgag tccaaagact
1021 caagatggaa cctgagggag agaaccaaga aagtgttggg agaggagcct ggaacaacgg
1081 acattttttc cagggagaca ctgctaagca agttgcccat cagtcgtctt gggaaatgga
1141 ttgagggttc ctggcttagc agctggtcct tgcacagtga ccttttcctc tgctcagtgc
1201 cgggatgaga gatggagtca tgagtgttga agaataagtg ccttctattt attttgagtc
1261 tgtgtgttct cactttgggc atgtaattat gactggtgaa ttctgacgac atgatagatc
1321 ttaagatgta gtcaccaaac tcaactgctg cttagcatcc tccgtaacta ctgatacaag
1381 cagggaacac agaggtcacc tgcttggttt gacaggctct tgctgtctga ctcaaataat
1441 ctttattttt cagtcctcaa ggctcttcga tagcagttgt tctgtatcag ccttataggt
1501 gtcaggtata gcactcaaca tctcatctca ttacaatagc aaccctcatc accatagcaa
1561 cagctaacct ctgttatcct cacttcatag ccaggaagct gagcgactaa gtcacttgcc
1621 cacagagtat cagctctcag atttctgttc ttcagccact gtcctttcag gatagaattt
1681 gtcgttaaga aattaattta aaaactgatt attgagtagc attgtatatc aatcacaaca
1741 tgccttgtgc actgtgctgg cctctgagca taaagatgta cgccggagta ccggtcggac
1801 atgtttatgt gtgttaaata ctcagagaaa tgttcattaa caaggagctt gcattttaga
1861 gacactggaa agtaactcca gttcattgtc tagcattaca tttacctcat ttgctatcct
1921 tgccatacag tctcttgttc tccatgaagt gtcatgaatc ttgttgaata gttcttttat
1981 tttttaaatg tttctattta aatgatattg acatctgagg cgatagctca gttggtaaaa
2041 ccctttcctc acaagtgtga aaccctgagt cttatcccta gaacccacat aaaaaacagt
2101 tgcgtatgtt tgtgcatgct tttgatccca gcactaggga ggcagaggca ggcagatcct
2161 gagctctcat tgaccaccca gcctagccta catggttagc tccaggccta caggagctgg
2221 cagagcctga aaaacgatgc ctagacacac acacacacac acacacacac acacacacac
2281 acacacacca tgtactcata gacctaagtg caccctccta cacatgcaca cacatacaat
2341 tcaaacacaa atcaacaggg aattgtctca gaatggtccc caagacaaag aagaagaaaa
2401 acaccaaacc agctctattc cctcagccta tcctctctac tccttcctag aagcaactac
2461 tattgttttt gtatataaat ttacccaacg acagttaata tgtagaatat atattaaagt
2521 gtctgtcaat atatattatc tctttctttc tttcttcctt tctttctttc tttctttctt
2581 tctttctttc tttctttctt tctttctttc ttccttcctt ccttccttcc ttccttcctt
2641 ccttcctttc tttctttctt tctttttttc tgtctatctg tacctaaatg gttgctcact
2701 atgcattttc tgtgctcttc gcccttttta tttaatgtat ggatatttat gctgcttcca
2761 gaatggatct aaagctcttt gtttctaggt tttctccccc atccttctag gcatctctca
2821 cactgtctag gccagacacc atgtctgctg cctgaatctg tagacaccat ttataaagca
2881 cgtactcacc gagtttgtat ttggcttgtt ctgtgtctga ttaaagggag accatgagtc
2941 cccagggtac actgagttac cccagtacca agggggagcc ttgtttgtgt ctccatggca
3001 gaagcaggcc tggagccatt ttggtttctt ccttgacttc tctcaaacac agacgcctca
3061 cttgctcatt acaggttctc ctttgggaat gtcagcattg ctccttgact gctggctgcc
3121 ctggaaggag cccattagct ctgtgtgagc ccttgacagc tactgcctct ccttaccaca
3181 ggggcctcta agatactgtt acctagaggt cttgaggatc tgtgttctct ggggggagga
3241 aaggaggagg aacccagaac tttcttacag ttttccttgt tctgtcacat gtcaagactg
3301 aaggaacagg ctgggctacg tagtgagatc ctgtctcaaa ggaaagacga gcatagccga
3361 acccccggtg gaaccccctc tgttacctgt tcacacaagc ttattgatga gtctcatgtt
3421 aatgtcttgt ttgtatgaag tttaagaaaa tatcgggttg ggcaacacat tctatttatt
3481 cattttattt gaaatcttaa tgccatctca tggtgttgga ttggtgtggc actttattct
3541 tttgtgttgt gtataaccat aaattttatt ttgcatcaga ttgtcaatgt attgcattaa
3601 tttaataaat atttttattt attaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3661 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//