LOCUS BC058287 1765 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens angiopoietin-like 3, mRNA (cDNA clone MGC:61934
IMAGE:4767228), complete cds.
ACCESSION BC058287
VERSION BC058287.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1765)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1765)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-SEP-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 48 Row: g Column: 2.
FEATURES Location/Qualifiers
source 1..1765
/db_xref="H-InvDB:HIT000259843"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:61934 IMAGE:4767228"
/tissue_type="Liver"
/clone_lib="NIH_MGC_76"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1765
/gene="ANGPTL3"
/db_xref="GeneID:27329"
/db_xref="HGNC:HGNC:491"
/db_xref="MIM:604774"
CDS 52..1434
/gene="ANGPTL3"
/codon_start=1
/product="angiopoietin-like 3"
/protein_id="AAH58287.1"
/db_xref="GeneID:27329"
/db_xref="HGNC:HGNC:491"
/db_xref="MIM:604774"
/translation="MFTIKLLLFIVPLVISSRIDQDNSSFDSLSPEPKSRFAMLDDVK
ILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRT
TYKLQVKNEEVKNMSLELNSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPE
VTSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSS
KPRAPRTTPFLQLNEIRNVKHDGIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDV
ISGSPWTLIQHRIDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIE
LEDWKDNKHYIEYSFYLGNHETNYTLHLVAITGNVPNAIPENKDLVFSTWDHKAKGHF
NCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTKML
IHPTDSESFE"
BASE COUNT 690 a 301 c 290 g 484 t
ORIGIN
1 ggggagaaga aaacagttcc acgttgcttg aaattgaaaa tcaagataaa aatgttcaca
61 attaagctcc ttctttttat tgttcctcta gttatttcct ccagaattga tcaagacaat
121 tcatcatttg attctctatc tccagagcca aaatcaagat ttgctatgtt agacgatgta
181 aaaattttag ccaatggcct ccttcagttg ggacatggtc ttaaagactt tgtccataag
241 acgaagggcc aaattaatga catatttcaa aaactcaaca tatttgatca gtctttttat
301 gatctatcgc tgcaaaccag tgaaatcaaa gaagaagaaa aggaactgag aagaactaca
361 tataaactac aagtcaaaaa tgaagaggta aagaatatgt cacttgaact caactcaaaa
421 cttgaaagcc tcctagaaga aaaaattcta cttcaacaaa aagtgaaata tttagaagag
481 caactaacta acttaattca aaatcaacct gaaactccag aacacccaga agtaacttca
541 cttaaaactt ttgtagaaaa acaagataat agcatcaaag accttctcca gaccgtggaa
601 gaccaatata aacaattaaa ccaacagcat agtcaaataa aagaaataga aaatcagctc
661 agaaggacta gtattcaaga acccacagaa atttctctat cttccaagcc aagagcacca
721 agaactactc cctttcttca gttgaatgaa ataagaaatg taaaacatga tggcattcct
781 gctgaatgta ccaccattta taacagaggt gaacatacaa gtggcatgta tgccatcaga
841 cccagcaact ctcaagtttt tcatgtctac tgtgatgtta tatcaggtag tccatggaca
901 ttaattcaac atcgaataga tggatcacaa aacttcaatg aaacgtggga gaactacaaa
961 tatggttttg ggaggcttga tggagaattt tggttgggcc tagagaagat atactccata
1021 gtgaagcaat ctaattatgt tttacgaatt gagttggaag actggaaaga caacaaacat
1081 tatattgaat attcttttta cttgggaaat cacgaaacca actatacgct acatctagtt
1141 gcgattactg gcaatgtccc caatgcaatc ccggaaaaca aagatttggt gttttctact
1201 tgggatcaca aagcaaaagg acacttcaac tgtccagagg gttattcagg aggctggtgg
1261 tggcatgatg agtgtggaga aaacaaccta aatggtaaat ataacaaacc aagagcaaaa
1321 tctaagccag agaggagaag aggattatct tggaagtctc aaaatggaag gttatactct
1381 ataaaatcaa ccaaaatgtt gatccatcca acagattcag aaagctttga atgaactgag
1441 gcaaatttaa aaggcaataa tttaaacatt aacctcattc caagttaatg tggtctaata
1501 atctggtatt aaatccttaa gagaaagctt gagaaataga ttttttttat cttaaagtca
1561 ctgtctattt aagattaaac atacaatcac ataaccttaa agaataccgt ttacatttct
1621 caatcaaaat tcttataata ctatttgttt taaattttgt gatgtgggaa tcaattttag
1681 atggtcacaa tctagattat aatcaatagg tgaacttatt aaataacttt tctaaataaa
1741 aaaaaaaaaa aaaaaaaaaa aaaaa
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