LOCUS BC058162 3225 bp mRNA linear ROD 08-OCT-2003
DEFINITION Mus musculus receptor (TNFRSF)-interacting serine-threonine kinase
1, mRNA (cDNA clone MGC:68261 IMAGE:5135235), complete cds.
ACCESSION BC058162
VERSION BC058162.1
KEYWORDS MGC.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 3225)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3225)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (15-SEP-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Jeffrey E. Green, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 123 Row: h Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6677752.
FEATURES Location/Qualifiers
source 1..3225
/organism="Mus musculus"
/mol_type="mRNA"
/strain="FVB/N"
/db_xref="taxon:10090"
/clone="MGC:68261 IMAGE:5135235"
/tissue_type="Liver, normal. 5 month old male mouse."
/clone_lib="NCI_CGAP_Li9"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3225
/gene="Ripk1"
/gene_synonym="RIP"
/db_xref="GeneID:19766"
/db_xref="MGI:MGI:108212"
CDS 323..2293
/gene="Ripk1"
/gene_synonym="RIP"
/codon_start=1
/product="Ripk1 protein"
/protein_id="AAH58162.1"
/db_xref="GeneID:19766"
/db_xref="MGI:MGI:108212"
/translation="MQPDMSLDNIKMASSDLLEKTDLDSGGFGKVSLCYHRSHGFVIL
KKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNLMH
VLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGVIHKDLKPENILVDRDFHIKIADLGVA
SFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDVYSFGIV
LWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQAIPEDR
PTFLGIEEEFRPFYLSHFEEYVEEDVASLKKEYPDQSPVLQRMFSLQHDCVPLPPSRS
NSEQPGSLHSSQGLQMGPVEESWFSSSPEYPQDENDRSVQAKLQEEASYHAFGIFAEK
QTKPQPRQNEAYNREEERKRRVSHDPFAQQRARENIKSAGARGHSDPSTTSRGIAVQQ
LSWPATQTVWNNGLYNQHGFGTTGTGVWYPPNLSQMYSTYKTPVPETNIPGSTPTMPY
FSGPVADDLIKYTIFNSSGIQIGNHNYMDVGLNSQPPNNTCKEESTSRHQAIFDNTTS
LTDEHLNPIRENLGRQWKNCARKLGFTESQIDEIDHDYERDGLKEKVYQMLQKWLMRE
GTKGATVGKLAQALHQCCRIDLLNHLIRASQS"
misc_feature 389..1180
/gene="Ripk1"
/gene_synonym="RIP"
/note="TyrKc; Region: Tyrosine kinase, catalytic domain"
/db_xref="CDD:smart00219"
misc_feature 2027..2281
/gene="Ripk1"
/gene_synonym="RIP"
/note="death; Region: Death domain"
/db_xref="CDD:pfam00531"
BASE COUNT 958 a 720 c 834 g 713 t
ORIGIN
1 gagcgcgggt gtcggtgccg ctcacctccc gggagtccag cggcggtgcg gacccgcgga
61 ggtgcgagct ggacgcggcg ggaggcggca ggctgtgggg gacctgcgag tggctgggcg
121 ccacttcagc accgaactcc gaccggtcct cgtcagggcc cagggccgtc ccggccgggc
181 agccacggcg aggcgccgct cctgacgtcc accgcccgtc cttcctcacc taggccgggg
241 tacttggccg cgggaaggcc tctgaggaca cagcactaag caagaaccaa aagtggtgtg
301 ttggagattc tgagcaatca aaatgcaacc agacatgtcc ttggacaata ttaagatggc
361 atccagtgac ctgctggaga agacagacct agacagcgga ggcttcggga aggtgtcctt
421 gtgttaccac agaagccatg gatttgtcat cctgaaaaaa gtatacacag ggcccaaccg
481 cgctgagtac aatgaggttc tcttggaaga ggggaagatg atgcacagac tgagacacag
541 tcgagtggtg aagctactgg gcatcatcat agaagaaggg aactattcgc tggtgatgga
601 gtacatggag aagggcaacc tgatgcacgt gctaaagacc cagatagatg tcccactttc
661 attgaaagga aggataatcg tggaggccat agaaggcatg tgctacttac atgacaaagg
721 tgtgatacac aaggacctga agcctgagaa tatcctcgtt gatcgtgact ttcacattaa
781 gatagccgat cttggtgtgg cttcctttaa gacatggagc aaactgacta aggagaaaga
841 caacaagcag aaagaagtga gcagcaccac taagaagaac aatggtggta ccctttacta
901 catggcaccc gaacacctga atgacatcaa tgcaaagccc acggagaagt cggacgtgta
961 cagctttggc attgtccttt gggcaatatt tgcaaaaaag gagccctatg agaatgtcat
1021 ctgtactgag cagttcgtga tctgcataaa atctgggaac aggccaaatg tagaggaaat
1081 ccttgagtac tgtccaaggg agatcatcag cctcatggag cggtgctggc aggcgatccc
1141 agaagacagg ccaacatttc ttggcattga agaagaattt aggccttttt acttaagtca
1201 ttttgaagaa tatgtagaag aggatgtggc aagtttaaag aaagagtatc cagatcaaag
1261 cccagtgctg cagagaatgt tttcactgca gcatgactgt gtacccttac ctccgagcag
1321 gtcaaattca gaacaacctg gatcgctgca cagttcccag gggctccaga tgggtcctgt
1381 ggaggagtcc tggttttctt cctccccaga gtacccacag gacgagaatg atcgcagtgt
1441 gcaggctaag ctgcaagagg aagccagcta tcatgctttt ggaatatttg cagagaaaca
1501 gacaaaaccg cagccaaggc agaatgaggc ttacaacaga gaggaggaaa ggaaacgaag
1561 ggtctctcat gacccctttg cacagcagag agctcgtgag aatattaaga gtgcaggagc
1621 aagaggtcat tctgatccca gcacaacgag tcgtggaatt gcagtgcaac agctgtcatg
1681 gccagccacc caaacagttt ggaacaatgg attgtataat cagcatggat ttggaactac
1741 aggtacagga gtttggtatc cgccaaatct aagccaaatg tatagtactt ataaaactcc
1801 agtgccagag accaacatac cgggaagcac acccaccatg ccatacttct ctgggccagt
1861 agcagatgac ctcataaaat atactatatt caatagttct ggtattcaga ttggaaacca
1921 caattatatg gatgttggac tgaattcaca accaccaaac aatacttgca aagaagagtc
1981 gacttccaga caccaagcca tctttgataa caccactagt ctgactgatg aacacctgaa
2041 ccctatcagg gaaaacctgg gaaggcagtg gaaaaactgt gcccgcaagc tgggcttcac
2101 tgagtctcag atcgatgaaa tcgaccatga ctatgaaaga gatggactga aagagaaagt
2161 ttaccaaatg cttcagaagt ggctgatgcg ggaaggcacc aaaggggcca cagtgggaaa
2221 gttggcccag gcacttcacc aatgttgcag gatagacctg ctgaaccact tgattcgtgc
2281 cagccagagc taagcctggg caggctctgg cagtgggaag caaactattt gtctggtgca
2341 caaaccccgt ttgcccacta gccttcagaa ctctatctca gcatgagctc tgcatttgag
2401 cacacagggt catgcagttt ggaactggtg gatgggaaga gaaatctgaa gcccacagtg
2461 attcttcaga acatgcaagc ataaagaccg ctgaatgaat ggtcggtcca tgaccagtag
2521 gaggaaaaaa attaaaaata cagtgtattg agttttcaaa gggagagaag atgttggggg
2581 aaggtggcct tcgttcagct tgtgtcatag tcatcactta ggttatttgc tcagtttcct
2641 gtggtttcat tgggtaaggg gaaaacaaac aaaaaacatt caaagaatgt aaaatcagct
2701 agcttcccgc ttcatggact gtgagtcaga aaagttctgc tcaaatgcct tctatgagcc
2761 acggctcttc taaaaactat aggatctgtt aacttgagca tccaatgctg tactgtcacc
2821 ttaagcttta agaatcatgt gtaattctag tctatcaaat tatcaattag tgagagattt
2881 ttaaggagtg ctaaggagaa aaaggtgcag ggcagagaga gatcttcagg tactggctgt
2941 cattgcagct caggtactgg ctgtcattgc agagctgctg ctggttctgg ctgctgtaaa
3001 aagtctactt ttaagtttct aaagtttctc taccattctg gcgcttcatg cagtttccca
3061 ccctgtgagc cccacagagg gaacagatgt gcaggaaaca ctgatcggga aataccatct
3121 cctcctctct ggatatgact ggtgccttag cactgttccc tgtgcccaat aaactgtttc
3181 ctcagtttta aaaaaaaaaa aaaaaaaaac aaaaaaaaaa aaaaa
//