LOCUS BC052683 1883 bp mRNA linear ROD 02-DEC-2006 DEFINITION Mus musculus cytotoxic T-lymphocyte-associated protein 4, mRNA (cDNA clone MGC:60618 IMAGE:30072821), complete cds. ACCESSION BC052683 VERSION BC052683.1 KEYWORDS MGC. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. REFERENCE 1 (bases 1 to 1883) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. CONSRTM Mammalian Gene Collection Program Team TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 1883) CONSRTM NIH MGC Project TITLE Direct Submission JOURNAL Submitted (16-MAY-2003) National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov COMMENT Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: Drs. Dennis Taub, Dan Longo (NIA, USA), Jonathan Keller (NCI, USA) cDNA Library Preparation: Yulan Piao and Minoru Ko (National Institute on Aging, NIH: http://lgsun.grc.nia.nih.gov/cDNA/) cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: National Institutes of Health Intramural Sequencing Center (NISC), Gaithersburg, Maryland; Web site: http://www.nisc.nih.gov/ Contact: nisc_mgc@nhgri.nih.gov Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B., Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S., Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P., Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R., Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C., McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W., Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L., Young,A., Zhang,L.-H. and Green,E.D. Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAK Plate: 112 Row: o Column: 7 This clone was selected for full length sequencing because it passed the following selection criteria: matched mRNA gi: 31981846. FEATURES Location/Qualifiers source 1..1883 /organism="Mus musculus" /mol_type="mRNA" /strain="C57BL/6NCr" /db_xref="taxon:10090" /clone="MGC:60618 IMAGE:30072821" /tissue_type="Hematopoietic Stem Cell, (Lin-/c-Kit-/Sca-1+), mouse, 10 wks" /clone_lib="NIA Mouse Hematopoietic Stem Cell (Lin-/c-Kit-/Sca-1+) cDNA Library (Long)" /lab_host="DH10B" /note="Vector: pSPORT1" gene 1..1883 /gene="Ctla4" /gene_synonym="Ly-56" /db_xref="GeneID:12477" /db_xref="MGI:MGI:88556" CDS 67..738 /gene="Ctla4" /gene_synonym="Ly-56" /codon_start=1 /product="cytotoxic T-lymphocyte-associated protein 4" /protein_id="AAH52683.1" /db_xref="GeneID:12477" /db_xref="MGI:MGI:88556" /translation="MACLGLRRYKAQLQLPSRTWPFVALLTLLFIPVFSEAIQVTQPS VVLASSHGVASFPCEYSPSHNTDEVRVTVLRQTNDQMTEVCATTFTEKNTVGFLDYPF CSGTFNESRVNLTIQGLRAVDTGLYLCKVELMYPPPYFVGMGNGTRIYVIDPEPCPDS DFLLWILVAVSLGLFFYSFLVTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPY FIPIN" BASE COUNT 533 a 375 c 414 g 561 t ORIGIN 1 aagaggtaat cccctgttgg gttttactct gctccctgag gacctcagca catttgcccc 61 ccagccatgg cttgtcttgg actccggagg tacaaagctc aactgcagct gccttctagg 121 acttggcctt ttgtagccct gctcactctt cttttcatcc cagtcttctc tgaagccata 181 caggtgaccc aaccttcagt ggtgttggct agcagccatg gtgtcgccag ctttccatgt 241 gaatattcac catcacacaa cactgatgag gtccgggtga ctgtgctgcg gcagacaaat 301 gaccaaatga ctgaggtctg tgccacgaca ttcacagaga agaatacagt gggcttccta 361 gattacccct tctgcagtgg tacctttaat gaaagcagag tgaacctcac catccaagga 421 ctgagagctg ttgacacggg actgtacctc tgcaaggtgg aactcatgta cccaccgcca 481 tactttgtgg gcatgggcaa cgggacgcgg atttatgtca ttgatccaga accatgcccg 541 gattctgact tcctcctttg gatccttgtc gcagttagct tggggttgtt tttttacagt 601 ttcctggtca ctgctgtttc tttgagcaag atgctaaaga aaagaagtcc tcttacaaca 661 ggggtctatg tgaaaatgcc cccaacagag ccagaatgtg aaaagcaatt tcagccttat 721 tttattccca tcaactgaaa ggccgtttat gaagaagaag gagcatactt cagtctctaa 781 aagctgaggc aatttcaact ttccttttct ctccagctat ttttacctgt ttgtatattt 841 taaggagagt atgcctctct ttaatagaaa gctggatgca aaattccaat taagcatact 901 acaatttaaa gctaaggagc atgaacagag agctgggata tttctgttgt gtcagaacca 961 ttttactaaa agcatcactt ggaagcagca taaggatata gcattatggt gtggggtcaa 1021 gggaacatta gggaatggca cagcccaaag aaaggaaggg ggtgaaggaa gagattatat 1081 tgtacacatc ttgtatttac ctgagagatg tttatgactt aaataatttt taaatttttc 1141 atgctgttat tttctttaac aatgtataat tacacgaagg tttaaacatt tattcacaga 1201 gctatgtgac atagccagtg gttccaaagg ttgtagtgtt ccaagatgta tttttaagta 1261 atattgtaca tgggtgtttc atgtgctgtt gtgtatttgc tggtggtttg aatataaaca 1321 ctatgtatca gtgtcgtccc acagtgggtc ctggggaggt ttggctgggg agcttaggac 1381 actaatccat caggttggac tcgaggtcct gcaccaactg gcttggaaac tagatgaggc 1441 tgtcacaggg ctcagttgca taaaccgatg gtgatggagc gtaaactggg tctttacact 1501 cattttattt tttgtttctg cttttgtttt cttcaatgat ttgcaaggaa accaaaagct 1561 ggcagtgttt gtatgaacct gacagaacac tgtcttcaag gaaatgcctc attcctgaga 1621 ccagtaggtt tgttttttta ggaagttcca atactaggac cccctacaag tactatggct 1681 cctcgaaaac acaaagttaa tgccacagga agcagcagat ggtaggatgg gatgcacaag 1741 agttcctgaa aactaacact gttagtgttt tttttttaac tcaatatttt ccatgaaaat 1801 gcaaccacat gtataatatt tttaattaaa taaaagtttc ttgtgattgt ttaaaaaaaa 1861 aaaaaaaaaa aaaaaaaaaa aaa //