LOCUS       BC052683                1883 bp    mRNA    linear   ROD 02-DEC-2006
DEFINITION  Mus musculus cytotoxic T-lymphocyte-associated protein 4, mRNA
            (cDNA clone MGC:60618 IMAGE:30072821), complete cds.
ACCESSION   BC052683
VERSION     BC052683.1
KEYWORDS    MGC.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1883)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 1883)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2003) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Drs. Dennis Taub, Dan Longo (NIA, USA),
            Jonathan Keller (NCI, USA)
            cDNA Library Preparation: Yulan Piao and Minoru Ko (National
            Institute on Aging, NIH: http://lgsun.grc.nia.nih.gov/cDNA/)
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: National Institutes of Health Intramural
            Sequencing Center (NISC),
            Gaithersburg, Maryland;
            Web site: http://www.nisc.nih.gov/
            Contact: nisc_mgc@nhgri.nih.gov
            Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
            Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
            Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
            Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
            Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
            McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
            Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
            Young,A., Zhang,L.-H. and Green,E.D.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 112 Row: o Column: 7
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 31981846.
FEATURES             Location/Qualifiers
     source          1..1883
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6NCr"
                     /db_xref="taxon:10090"
                     /clone="MGC:60618 IMAGE:30072821"
                     /tissue_type="Hematopoietic Stem Cell,
                     (Lin-/c-Kit-/Sca-1+), mouse, 10 wks"
                     /clone_lib="NIA Mouse Hematopoietic Stem Cell
                     (Lin-/c-Kit-/Sca-1+) cDNA Library (Long)"
                     /lab_host="DH10B"
                     /note="Vector: pSPORT1"
     gene            1..1883
                     /gene="Ctla4"
                     /gene_synonym="Ly-56"
                     /db_xref="GeneID:12477"
                     /db_xref="MGI:MGI:88556"
     CDS             67..738
                     /gene="Ctla4"
                     /gene_synonym="Ly-56"
                     /codon_start=1
                     /product="cytotoxic T-lymphocyte-associated protein 4"
                     /protein_id="AAH52683.1"
                     /db_xref="GeneID:12477"
                     /db_xref="MGI:MGI:88556"
                     /translation="MACLGLRRYKAQLQLPSRTWPFVALLTLLFIPVFSEAIQVTQPS
                     VVLASSHGVASFPCEYSPSHNTDEVRVTVLRQTNDQMTEVCATTFTEKNTVGFLDYPF
                     CSGTFNESRVNLTIQGLRAVDTGLYLCKVELMYPPPYFVGMGNGTRIYVIDPEPCPDS
                     DFLLWILVAVSLGLFFYSFLVTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPY
                     FIPIN"
BASE COUNT          533 a          375 c          414 g          561 t
ORIGIN      
        1 aagaggtaat cccctgttgg gttttactct gctccctgag gacctcagca catttgcccc
       61 ccagccatgg cttgtcttgg actccggagg tacaaagctc aactgcagct gccttctagg
      121 acttggcctt ttgtagccct gctcactctt cttttcatcc cagtcttctc tgaagccata
      181 caggtgaccc aaccttcagt ggtgttggct agcagccatg gtgtcgccag ctttccatgt
      241 gaatattcac catcacacaa cactgatgag gtccgggtga ctgtgctgcg gcagacaaat
      301 gaccaaatga ctgaggtctg tgccacgaca ttcacagaga agaatacagt gggcttccta
      361 gattacccct tctgcagtgg tacctttaat gaaagcagag tgaacctcac catccaagga
      421 ctgagagctg ttgacacggg actgtacctc tgcaaggtgg aactcatgta cccaccgcca
      481 tactttgtgg gcatgggcaa cgggacgcgg atttatgtca ttgatccaga accatgcccg
      541 gattctgact tcctcctttg gatccttgtc gcagttagct tggggttgtt tttttacagt
      601 ttcctggtca ctgctgtttc tttgagcaag atgctaaaga aaagaagtcc tcttacaaca
      661 ggggtctatg tgaaaatgcc cccaacagag ccagaatgtg aaaagcaatt tcagccttat
      721 tttattccca tcaactgaaa ggccgtttat gaagaagaag gagcatactt cagtctctaa
      781 aagctgaggc aatttcaact ttccttttct ctccagctat ttttacctgt ttgtatattt
      841 taaggagagt atgcctctct ttaatagaaa gctggatgca aaattccaat taagcatact
      901 acaatttaaa gctaaggagc atgaacagag agctgggata tttctgttgt gtcagaacca
      961 ttttactaaa agcatcactt ggaagcagca taaggatata gcattatggt gtggggtcaa
     1021 gggaacatta gggaatggca cagcccaaag aaaggaaggg ggtgaaggaa gagattatat
     1081 tgtacacatc ttgtatttac ctgagagatg tttatgactt aaataatttt taaatttttc
     1141 atgctgttat tttctttaac aatgtataat tacacgaagg tttaaacatt tattcacaga
     1201 gctatgtgac atagccagtg gttccaaagg ttgtagtgtt ccaagatgta tttttaagta
     1261 atattgtaca tgggtgtttc atgtgctgtt gtgtatttgc tggtggtttg aatataaaca
     1321 ctatgtatca gtgtcgtccc acagtgggtc ctggggaggt ttggctgggg agcttaggac
     1381 actaatccat caggttggac tcgaggtcct gcaccaactg gcttggaaac tagatgaggc
     1441 tgtcacaggg ctcagttgca taaaccgatg gtgatggagc gtaaactggg tctttacact
     1501 cattttattt tttgtttctg cttttgtttt cttcaatgat ttgcaaggaa accaaaagct
     1561 ggcagtgttt gtatgaacct gacagaacac tgtcttcaag gaaatgcctc attcctgaga
     1621 ccagtaggtt tgttttttta ggaagttcca atactaggac cccctacaag tactatggct
     1681 cctcgaaaac acaaagttaa tgccacagga agcagcagat ggtaggatgg gatgcacaag
     1741 agttcctgaa aactaacact gttagtgttt tttttttaac tcaatatttt ccatgaaaat
     1801 gcaaccacat gtataatatt tttaattaaa taaaagtttc ttgtgattgt ttaaaaaaaa
     1861 aaaaaaaaaa aaaaaaaaaa aaa
//