LOCUS       BC050350                3850 bp    mRNA    linear   HUM 17-JUL-2006
DEFINITION  Homo sapiens TCDD-inducible poly(ADP-ribose) polymerase, mRNA (cDNA
            clone MGC:51185 IMAGE:5264807), complete cds.
ACCESSION   BC050350
VERSION     BC050350.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3850)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 3850)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-APR-2003) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
            cDNA Library Preparation: Michael J. Brownstein (NHGRI) &  Shiraki
            Toshiyuki and Piero Carninci (RIKEN)
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:       http://www-shgc.stanford.edu
            Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 90 Row: o Column: 21
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 38524593.
FEATURES             Location/Qualifiers
     source          1..3850
                     /db_xref="H-InvDB:HIT000053419"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:51185 IMAGE:5264807"
                     /tissue_type="Brain, hippocampus"
                     /clone_lib="NIH_MGC_95"
                     /lab_host="DH10B"
                     /note="Vector: pBluescriptR"
     gene            1..3850
                     /gene="TIPARP"
                     /gene_synonym="DDF1"
                     /gene_synonym="DKFZP434J214"
                     /gene_synonym="DKFZp686N0351"
                     /gene_synonym="PARP-1"
                     /gene_synonym="PARP-7"
                     /gene_synonym="PARP7"
                     /db_xref="GeneID:25976"
                     /db_xref="HGNC:HGNC:23696"
     CDS             230..2203
                     /gene="TIPARP"
                     /gene_synonym="DDF1"
                     /gene_synonym="DKFZP434J214"
                     /gene_synonym="DKFZp686N0351"
                     /gene_synonym="PARP-1"
                     /gene_synonym="PARP-7"
                     /gene_synonym="PARP7"
                     /codon_start=1
                     /product="TCDD-inducible poly(ADP-ribose) polymerase"
                     /protein_id="AAH50350.2"
                     /db_xref="GeneID:25976"
                     /db_xref="HGNC:HGNC:23696"
                     /translation="MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKD
                     QKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPP
                     AENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQ
                     TDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEA
                     SLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQ
                     KWQSVFNDSQEHLERFYCNPENDRMRMKYGGQEFWADLNAMNVYETTEFDQLRRLSTP
                     PSSNVNSIYHTVWKFFCRDHFGWREYPESVIRLIEEANSRGLKEVRFMMWNNHYILHN
                     SFFRREIKRRPLFSSCFILLPYLQTLGGVPTQAPPPLEATSSSQIICPDGVTSANFYP
                     ETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYK
                     RKKEYMNRKMFGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFA
                     KKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVD
                     NFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI"
BASE COUNT         1139 a          780 c          787 g         1144 t
ORIGIN      
        1 gggctggctg gactcggagc gcggtcgagg ctttctgcgt tcgcggcggc ggaatggccc
       61 gtgcgcggct cgccgcgtcg cggctctgtg gtccgtagac gtcggctccc gccctcggcg
      121 ctgatctccg gcgcgggcac tgctttccac tcggctcctg tcgtccgttc tctcaggctc
      181 ccgttcagga tttttagact ctgaggagca gttggagcta atccacatta tggaaatgga
      241 aaccaccgaa cctgagccag actgtgtagt gcagcctccc tctcctcctg atgacttttc
      301 atgccaaatg agactctctg agaagatcac tccattgaag acttgtttta agaaaaagga
      361 tcagaaaaga ttgggaactg gaaccctgag gtctttgagg ccaatattaa acactcttct
      421 agaatctggc tcacttgatg gggtttttag atctaggaac cagagtacag atgagaacag
      481 cttacatgaa cctatgatga agaaagccat ggaaatcaat tcatcatgcc caccagcaga
      541 aaataatatg tctgttctga ttcctgatag gacaaatgtt ggggaccaga taccggaagc
      601 ccatccttcc actgaagctc cagaacgagt ggttccaatc caagatcaca gctttccatc
      661 agaaaccctc agtgggacgg tggcagattc cacaccagct cacttccaga ctgatctttt
      721 gcacccagtt tcaagtgatg ttcctactag tcctgactgc ttagacaaag tcatagatta
      781 tgttccaggc attttccaag aaaacagttt tacaatccaa tacattctgg acaccagtga
      841 taagctgagt actgagctct ttcaggacaa aagtgaagag gcttcccttg acctcgtgtt
      901 tgagctggtg aaccagttgc agtaccacac tcaccaagag aacggaattg aaatttgcat
      961 ggactttctg caaggcactt gtatttatgg cagggattgt ttgaagcacc acactgtctt
     1021 gccatatcat tggcagatca aaaggacaac tactcaaaag tggcagagtg tattcaatga
     1081 ttctcaggag cacttggaaa gattttactg taacccagaa aatgatagaa tgagaatgaa
     1141 gtatggagga caagaatttt gggcagattt gaatgccatg aacgtgtatg aaacaactga
     1201 atttgaccaa ctacgaaggc tgtccacacc accctctagc aatgtcaact ctatttacca
     1261 cacagtctgg aaattcttct gtagggacca ctttggatgg agagagtatc ccgagtctgt
     1321 cattcgattg attgaagaag ccaactctcg gggtctgaaa gaggttcgat ttatgatgtg
     1381 gaataaccac tacatcctcc acaattcatt cttcaggaga gagataaaaa ggagacccct
     1441 cttcagctcc tgttttatac tgcttccata tttacagaca cttggtgggg ttcccacaca
     1501 agctcctcca cctcttgaag caacttcatc atcacaaatt atctgcccag atggggtcac
     1561 ttcagcaaac ttttaccctg aaacttgggt ttatatgcat ccatctcagg acttcatcca
     1621 agtccctgtt tctgcagagg ataaaagtta tcggatcatt tacaatcttt ttcataagac
     1681 tgtgcctgag tttaaataca gaattttgca gatattgaga gtccaaaacc agtttctttg
     1741 ggagaaatat aaaaggaaaa aggaatatat gaacaggaaa atgtttggcc gtgacaggat
     1801 aataaatgag agacatttat ttcatggaac atcccaggat gtggtagatg gaatctgcaa
     1861 acacaacttt gaccctcgag tctgtggaaa gcatgctaca atgtttggac aaggcagtta
     1921 ttttgcaaag aaggcaagct actctcataa cttttctaag aagtcctcca aaggagtcca
     1981 cttcatgttt ctggccaaag tgctgacggg cagatacaca atgggcagtc atggcatgag
     2041 aaggcccccg ccagtcaatc ctggcagtgt caccagtgac ctttatgact cttgtgtgga
     2101 taatttcttt gagcctcaga tttttgtcat ttttaatgat gaccagagtt acccttattt
     2161 tgttatccaa tatgaagaag tcagtaacac tgtttccatt tgaaaaatct tggtactgct
     2221 aaattatttg atatgaactc aatccagcat ttgtagcagg ttttgaatgg gtgggactgg
     2281 gtggggaaca gcattggaca ttaatagggc acttttcaga cccatttttt aaagtgctag
     2341 aaaatgcttt tttttaaaaa aaaatacaag ttttaaaatg accacttact ctttaattat
     2401 ttactaattg ctagtgtact cagtgtggaa aagactacag attacacact cttttcattc
     2461 acacttgtac atatagacag caatgttatt aggagcatta aattaaaaaa ctgaacagcc
     2521 taatttaaat gtggcttggg cctggtagaa gtttgaccaa atggaatgga ggctgtgagc
     2581 aatgagagga ttctatttat ttatttacgt ttgataaaac ttactggaac tagtactacc
     2641 atgcgtattc cctgtccaaa gcatcactgc tttggtatag tataagttca tgaaattctg
     2701 gtgggtagaa agaaattttt atttctatca gcagtactaa aatgtatcag ccaaccagag
     2761 aacatcagtg actttaactt ctgcagagtt tgccccagaa ttcagagttc tatttagagg
     2821 aagttaaaac aacaacaaaa aacaaccatt tgaaaaattt ttgtcaccag caaaactttt
     2881 cactaattag tgatatgaaa tgtgattttt gtgttgttaa acttcagctt tggaaaactc
     2941 agtctctttc attatcatcc attccaattt gaaggagttg ggcagctaat ttggttaaag
     3001 gcagtcttga gggttagaag tattacttcc ttttcgggtt ccagacctag cttgtgactg
     3061 aaagttttag aaaaaggaag tacatctata gccgaattga taaggttatt actgtgtttt
     3121 gcacaaagta tattagcaaa agtatttgct ggaattattg gtagatggca gtcccacccc
     3181 tacacctgct ttgtcagata cagctgggtt ccctggctga ctctgtacct tacttacact
     3241 acttacttaa tagaaacaca aacttggaaa ttgtgccagt ggtccagctg gagcacaacg
     3301 tttggtgaat atgctgtttc ctcagttcag agaggtagca actaggtaaa ctccttataa
     3361 aaagcaaata cctggattta caaaagtgaa agtagttgtt cacaaaagaa ttcgccatgg
     3421 aattctttca gttaccaagc tctcctggta atgtttgtgg ttatatcatt tacacaaaac
     3481 ttttcaggaa cttctgtgtt gtttaagcaa gatgtatctg tactgatgtc tcagtgaatc
     3541 agtctgttta ttaagcactt atcagggctt ccacacactt atttattttg ccctagttaa
     3601 tcctgttgtt tgctgccatt ggcatgaaat ggccaactgt ggctgttaca gttctttcat
     3661 tcaattataa cttgtaaacc agtgactcct aatctttttc aagttaagac accttaccat
     3721 tgcttatttg gttttatgag acttgttcct ttttttctcc ctaaggaaaa agctttatga
     3781 catatttatt tttttaataa aactaagcaa aaataaaact tatggtaatt ctttaaaaaa
     3841 aaaaaaaaaa
//