LOCUS BC044211 1942 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens serine hydroxymethyltransferase 2 (mitochondrial),
mRNA (cDNA clone MGC:49833 IMAGE:5521082), complete cds.
ACCESSION BC044211
VERSION BC044211.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1942)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1942)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-JAN-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 89 Row: d Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 52851445.
FEATURES Location/Qualifiers
source 1..1942
/db_xref="H-InvDB:HIT000052846"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:49833 IMAGE:5521082"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1942
/gene="SHMT2"
/gene_synonym="GLYA"
/db_xref="GeneID:6472"
/db_xref="HGNC:HGNC:10852"
/db_xref="MIM:138450"
CDS 47..1561
/gene="SHMT2"
/gene_synonym="GLYA"
/codon_start=1
/product="serine hydroxymethyltransferase 2
(mitochondrial)"
/protein_id="AAH44211.1"
/db_xref="GeneID:6472"
/db_xref="HGNC:HGNC:10852"
/db_xref="MIM:138450"
/translation="MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWT
GQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPG
KRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDR
IMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRP
RLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTT
TTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAA
VAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLD
GARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDE
GVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDEH"
BASE COUNT 431 a 537 c 550 g 424 t
ORIGIN
1 ctagaccaga gttggtggct ggacctcctg cgacttccga gttgcgatgc tgtacttctc
61 tttgttttgg gcggctcggc ctctgcagag atgtgggcag ctggtcagga tggccattcg
121 ggctcagcac agcaacgcag cccagactca gactggggaa gcaaacaggg gctggacagg
181 ccaggagagc ctgtcggaca gtgatcctga gatgtgggag ttgctgcaga gggagaagga
241 caggcagtgt cgtggcctgg agctcattgc ctcagagaac ttctgcagcc gagctgcgct
301 ggaggccctg gggtcctgtc tgaacaacaa gtactcggag ggttatcctg gcaagagata
361 ctatggggga gcagaggtgg tggatgaaat tgagctgctg tgccagcgcc gggccttgga
421 agcctttgac ctggatcctg cacagtgggg agtcaatgtc cagccctact ccgggtcccc
481 agccaacctg gccgtctaca cagcccttct gcaacctcac gaccggatca tggggctgga
541 cctgcccgat gggggccatc tcacccacgg ctacatgtct gacgtcaagc ggatatcagc
601 cacgtccatc ttcttcgagt ctatgcccta taagctcaac cccaaaactg gcctcattga
661 ctacaaccag ctggcactga ctgctcgact tttccggcca cggctcatca tagctggcac
721 cagcgcctat gctcgcctca ttgactacgc ccgcatgaga gaggtgtgtg atgaagtcaa
781 agcacacctg ctggcagaca tggcccacat cagtggcctg gtggctgcca aggtgattcc
841 ctcgcctttc aagcacgcgg acatcgtcac caccactact cacaagactc ttcgaggggc
901 caggtcaggg ctcatcttct accggaaagg ggtgaaggct gtggacccca agactggccg
961 ggagatccct tacacatttg aggaccgaat caactttgcc gtgttcccat ccctgcaggg
1021 gggcccccac aatcatgcca ttgctgcagt agctgtggcc ctaaagcagg cctgcacccc
1081 catgttccgg gagtactccc tgcaggttct gaagaatgct cgggccatgg cagatgccct
1141 gctagagcga ggctactcac tggtatcagg tggtactgac aaccacctgg tgctggtgga
1201 cctgcggccc aagggcctgg atggagctcg ggctgagcgg gtgctagagc ttgtatccat
1261 cactgccaac aagaacacct gtcctggaga ccgaagtgcc atcacaccgg gcggcctgcg
1321 gcttggggcc ccagccttaa cttctcgaca gttccgtgag gatgacttcc ggagagttgt
1381 ggactttata gatgaagggg tcaacattgg cttagaggtg aagagcaaga ctgccaagct
1441 ccaggatttc aaatccttcc tgcttaagga ctcagaaaca agtcagcgtc tggccaacct
1501 caggcaacgg gtggagcagt ttgccagggc cttccccatg cctggttttg atgagcattg
1561 aaggcacctg ggaaatgagg cccacagact caaagttact ctccttcccc ctacctgggc
1621 cagtgaaata gaaagccttt ctattttttg gtgcgggagg gaagacctct cacttagggc
1681 aagagccagg tatagtctcc cttcccagaa tttgtaactg agaagatctt ttctttttcc
1741 tttttttggt aacaagactt agaaggaggg cccaggcact ttctgtttga acccctgtca
1801 tgatcacagt gtcagagacg cgtcctcttt cttggggaag ttgaggagtg cccttcagag
1861 ccagtagcag gcaggggtgg gtaggcaccc tccttcctgt ttttatctaa taaaatgcta
1921 acctgcaaaa aaaaaaaaaa aa
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