LOCUS BC042741 1958 bp mRNA linear ROD 02-DEC-2006 DEFINITION Mus musculus cytotoxic T-lymphocyte-associated protein 4, mRNA (cDNA clone MGC:51581 IMAGE:4936052), complete cds. ACCESSION BC042741 VERSION BC042741.1 KEYWORDS MGC. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. REFERENCE 1 (bases 1 to 1958) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. CONSRTM Mammalian Gene Collection Program Team TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 1958) CONSRTM NIH MGC Project TITLE Direct Submission JOURNAL Submitted (02-JAN-2003) National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov COMMENT Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: Lothar Hennighausen Ph.D., Priscilla Furth Ph.D. cDNA Library Preparation: Life Technologies, Inc. cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: Baylor College of Medicine Human Genome Sequencing Center Center code: BCM-HGSC Web site: http://www.hgsc.bcm.tmc.edu/cdna/ Contact: amg@bcm.tmc.edu Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H., Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati, A.N., Gibbs, R.A. Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAK Plate: 92 Row: i Column: 7 This clone was selected for full length sequencing because it passed the following selection criteria: matched mRNA gi: 31981846. FEATURES Location/Qualifiers source 1..1958 /organism="Mus musculus" /mol_type="mRNA" /strain="NMRI" /db_xref="taxon:10090" /clone="MGC:51581 IMAGE:4936052" /tissue_type="Mammary tumor. WAP-Tag model. 5 months old, gross tissue." /clone_lib="NCI_CGAP_Mam4" /lab_host="DH10B" /note="Vector: pCMV-SPORT6" gene 1..1958 /gene="Ctla4" /gene_synonym="Ly-56" /db_xref="GeneID:12477" /db_xref="MGI:MGI:88556" CDS 147..818 /gene="Ctla4" /gene_synonym="Ly-56" /codon_start=1 /product="cytotoxic T-lymphocyte-associated protein 4" /protein_id="AAH42741.1" /db_xref="GeneID:12477" /db_xref="MGI:MGI:88556" /translation="MACLGLRRYKAQLQLPSRTWPFVALLTLLFIPVFSEAIQVTQPS VVLASSHGVASFPCEYSPSHNTDEVRVTVLRQTNDQMTEVCATTFTEKNTVGFLDYPF CSGTFNESRVNLTIQGLRAVDTGLYLCKVELMYPPPYFVGMGNGTQIYVIDPEPCPDS DFLLWILVAVSLGLFFYSFLVTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPY FIPIN" BASE COUNT 548 a 395 c 430 g 585 t ORIGIN 1 ctacacatat gtagcacgta ccttggatca aagctgtcta tataaagtcc ccgagtctgt 61 gtgggttcaa acacatctca aggcttctgg atcctgttgg gttttactct gctccctgag 121 gacctcagca catttgcccc ccagccatgg cttgtcttgg actccggagg tacaaagctc 181 aactgcagct gccttctagg acttggcctt ttgtagccct gctcactctt cttttcatcc 241 cagtcttctc tgaagccata caggtgaccc aaccttcagt ggtgttggct agcagccatg 301 gtgtcgccag ctttccatgt gaatattcac cgtcacacaa cactgatgag gtccgggtga 361 ctgtgctgcg gcagacaaat gaccaaatga ctgaggtctg tgccacgaca ttcacagaga 421 agaatacagt gggcttccta gattacccct tctgcagtgg tacctttaat gaaagcagag 481 tgaacctcac catccaagga ctgagagctg ttgacacggg actgtacctc tgcaaggtgg 541 aactcatgta cccaccgcca tactttgtgg gcatgggcaa cgggacgcag atttatgtca 601 ttgatccaga accatgcccg gattctgact tcctcctttg gatccttgtc gcagttagct 661 tggggttgtt tttttacagt ttcctggtca ctgctgtttc tttgagcaag atgctaaaga 721 aaagaagtcc tcttacaaca ggggtctatg tgaaaatgcc cccaacagag ccagaatgtg 781 aaaagcaatt tcagccttat tttattccca tcaactgaaa ggccgtttat gaagaagaag 841 gagcatactt cagtctctaa aagctgaggc aatttcaact ttccttttct ctccagctat 901 ttttacctgt ttgtatattt taaggagagt atgcctctct ttaatagaaa gctggatgca 961 aaattccaat taagcatact acaatttaaa gctaaggagc atgaacagag agctgggata 1021 tttctgttgt gtcagaacca ttttactaaa agcatcactt ggaagcagca taaggatata 1081 gcattatggt gtggggtcaa gggaacatta gggaatggca cagcccaaag aaaggaaggg 1141 ggtgaaggaa gagattatat tgtacacatc ttgtatttac ctgagagatg tttatgactt 1201 aaataatttt taaatttttc atgctgttat tttctttaac aatgtataat tacacgaagg 1261 tttaaacatt tattcacaga gctatgtgac atagccagtg gttccaaagg ttgtagtgtt 1321 ccaagatgta tttttaagta atattgtaca tgggtgtttc atgtgctgtt gtgtatttgc 1381 tggtggtttg aatataaaca ctatgtatca gtgtcgtccc acagtgggtc ctggggaggt 1441 ttggctgggg agcttaggac actaatccat caggttggac tcgaggtcct gcaccaactg 1501 gcttggaaac tagatgaggc tgtcacaggg ctcagttgca taaaccgatg gtgatggagt 1561 gtaaactggg tctttacact cattttattt tttgtttctg cttttgtttt cttcaatgat 1621 ttgcaaggaa accaaaagct ggcagtgttt gtatgaacct gacagaacac tgtcttcaag 1681 gaaatgcctc attcctgaga ccagtaggtc tgttttttta ggaagttcca atactaggac 1741 cccctacaag tactatggct cctcgaaaac acaaagttaa tgccacagga agcagcagat 1801 ggtaggatgg gatgcacaag agttcctgaa aactaacact gttagtgttt ttttttttaa 1861 ctcaatattt tccatgaaaa tgcaaccaca tgtataatat ttttaattaa ataaaagttt 1921 cttgtgattg ttaaaaaaaa aaaaaaaaaa aaaaaaaa //