LOCUS BC042103 2465 bp mRNA linear HUM 25-MAR-2004
DEFINITION Homo sapiens pleckstrin homology domain containing, family M (with
RUN domain) member 2, mRNA (cDNA clone IMAGE:4523390), partial cds.
ACCESSION BC042103
VERSION BC042103.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2465)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2465)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (23-DEC-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 88 Row: b Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..2465
/db_xref="H-InvDB:HIT000097128"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4523390"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..2465
/gene="PLEKHM2"
/gene_synonym="KIAA0842"
/db_xref="GeneID:23207"
CDS <1..1617
/gene="PLEKHM2"
/gene_synonym="KIAA0842"
/codon_start=1
/product="PLEKHM2 protein"
/protein_id="AAH42103.1"
/db_xref="GeneID:23207"
/translation="HDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQ
ELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHS
SEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKG
ATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLK
SAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDES
LGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIP
LLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVS
KGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKE
YCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKK
KFEDALSLIHSAWQRSDSLCRGRASRDPWC"
misc_feature 871..1176
/gene="PLEKHM2"
/gene_synonym="KIAA0842"
/note="PH; Region: PH domain. PH stands for pleckstrin
homology"
/db_xref="CDD:pfam00169"
BASE COUNT 497 a 757 c 750 g 461 t
ORIGIN
1 catgaccctg cagggcttgg ccaaccgctg catgttccta gtagccctga ggctgctggc
61 caagaagaag agggaggagg aggagaggga cagacgcctc ggcccctaga ggataccacg
121 agggaggctc aggagctgga ggcccagctg tccctggtca gggaggggcc tgtgtctgag
181 ccagagcctg ggacccagga ggttctctgc cagctcaagc gagaccagcc cagcccgtgt
241 ctgagtagcg ctgaggattc tggggtggat gagggacagg ggagcccttc ggagatggtc
301 cattcctcgg agttcagagt agacaacaat cacctgctcc tgctcatgat ccacgtgttc
361 cgagaaaacg aagagcagct gttcaaaatg atccggatga gcaccgggca catggagggc
421 aacctgcagc tgctgtacgt gctgctcaca gactgctatg tctacctgct ccggaaaggg
481 gccacagaga agccatacct ggtggaagag gccgtttctt acaatgaact tgactatgtg
541 tcggttggcc ttgaccagca gacggtgaag ctggtgtgca ccaaccgcag gaagcagttt
601 ctgctggaca cggctgatgt ggcgctggct gagttctttt tggcttcttt gaagtcagcc
661 atgatcaaag gctgtcgaga acctccctac cccagcatcc tgacggatgc caccatggag
721 aagctggcac tggccaaatt tgtggcccaa gaatcgaagt gtgaggcatc tgctgtcacc
781 gtgcgcttct acggccttgt gcactgggag gaccccacag acgagtccct gggccccacg
841 ccctgccact gctcaccccc cgagggcacc atcaccaaag aaggcatgct gcactacaag
901 gcgggcacct cctacctggg caaggaacac tggaagacgt gcttcgtggt gctcagcaac
961 gggatcctct accagtaccc ggaccgcacc gacgtcatcc ctctgctctc ggtgaacatg
1021 gggggggagc agtgcggtgg ctgccggaga gccaacacca cggatcggcc ccacgccttc
1081 caggtcattc tctccgaccg gccctgcctg gagctaagtg ccgagagcga ggccgagatg
1141 gccgagtgga tgcagcatct ctgccaggct gtgtccaaag gggtcatccc ccagggcgta
1201 gctcccagcc cctgcatacc ctgctgcctg gtcctcacgg atgaccgcct ctttacgtgc
1261 catgaggatt gccagaccag cttcttccgc tctttgggca cagccaagct gggcgacatc
1321 agcgccgtct ccaccgagcc gggcaaggag tactgcgtct tggagttctc ccaggacagc
1381 cagcagctcc tcccgccctg ggtcatctac ctgagctgca cttctgaact ggaccgattg
1441 ctgtctgcac tgaactctgg gtggaaaacc atctatcagg tggacctccc ccacacggcg
1501 atccaggaag cctccaacaa gaagaaattc gaggatgcct tgagcctcat ccacagcgcc
1561 tggcagcgga gcgacagtct ctgccgcggc cgagcctccc gagacccctg gtgctgaggc
1621 agagctggtt ggcgtccctg gtgggcagga aaggaaggca cgccagccgg caggcacact
1681 gtcacggctg ttgtcatgct gtcgggagcc tacagtccac ccctgccctg ggcggcagaa
1741 ccaccgagtg tggcttaaga cagggtccct ccactccagg gatccagatc aggtgcccgg
1801 cacccctggg catcctgccc gacaggtagc gaatggaggt cgctgggggc agagggtccg
1861 agccctgtgg gctctgcgga tgcacgccct cctcccgggc ctccgcctca gtctgcagaa
1921 tttctgccga gtggcaccga gaacaccatc catctaagga cgaacaaaag aaccaggagg
1981 gcgggacccc cctcttcctc tcctgggttg ggggctgggg ccctgagtgc ccagccatcc
2041 ttgttcgtgt ttgaacactc tcctggccac gtggggaagc gggaacacgg ggtgtctgcg
2101 catgtttcct cctcctagct ccatcactgc gcacacagct gcctgcctcg ccagatgcag
2161 gggggcgggc agccctccct ggctgccagg aggctctgca tgcccacagt cctgccctgc
2221 ctgtcccctc aacccggcag tgcctgtagc accgaggagc aaagggggtg gatggggggc
2281 ttggagaagg gcggagccca ccagcctggc atccatgttg acatcttctg actgtcccct
2341 gcttggctgg agccaggccc ttccctagag tttcgtcaag agcctcctgg ggaaggggtc
2401 aggtggtttg ggttttgttt tttaaaataa aatagacatg ttatattgcc aaaaaaaaaa
2461 aaaaa
//