LOCUS BC039902 3348 bp mRNA linear HUM 24-JUL-2006
DEFINITION Homo sapiens angiotensin I converting enzyme (peptidyl-dipeptidase
A) 2, mRNA (cDNA clone MGC:47598 IMAGE:5243048), complete cds.
ACCESSION BC039902
VERSION BC039902.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3348)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3348)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 82 Row: f Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 11225608.
FEATURES Location/Qualifiers
source 1..3348
/db_xref="H-InvDB:HIT000095947"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:47598 IMAGE:5243048"
/tissue_type="Brain, fetal, whole pooled"
/clone_lib="NIH_MGC_121"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3348
/gene="ACE2"
/gene_synonym="ACEH"
/gene_synonym="DKFZP434A014"
/db_xref="GeneID:59272"
/db_xref="HGNC:HGNC:13557"
/db_xref="MIM:300335"
CDS 19..2436
/gene="ACE2"
/gene_synonym="ACEH"
/gene_synonym="DKFZP434A014"
/codon_start=1
/product="angiotensin I converting enzyme
(peptidyl-dipeptidase A) 2"
/protein_id="AAH39902.1"
/db_xref="GeneID:59272"
/db_xref="HGNC:HGNC:13557"
/db_xref="MIM:300335"
/translation="MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSS
LASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ
NGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNE
RLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYS
RGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWT
NLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLT
DPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLL
RNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTL
PFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSN
DYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPW
TLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISL
KSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFN
FFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVS
IWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNPGFQNT
DDVQTSF"
BASE COUNT 1049 a 635 c 747 g 917 t
ORIGIN
1 cttggctcac aggggacgat gtcaagctct tcctggctcc ttctcagcct tgttgctgta
61 actgctgctc agtccaccat tgaggaacag gccaagacat ttttggacaa gtttaaccac
121 gaagccgaag acctgttcta tcaaagttca cttgcttctt ggaattataa caccaatatt
181 actgaagaga atgtccaaaa catgaataat gctggggaca aatggtctgc ctttttaaag
241 gaacagtcca cacttgccca aatgtatcca ctacaagaaa ttcagaatct cacagtcaag
301 cttcagctgc aggctcttca gcaaaatggg tcttcagtgc tctcagaaga caagagcaaa
361 cggttgaaca caattctaaa tacaatgagc accatctaca gtactggaaa agtttgtaac
421 ccagataatc cacaagaatg cttattactt gaaccaggtt tgaatgaaat aatggcaaac
481 agtttagact acaatgagag gctctgggct tgggaaagct ggagatctga ggtcggcaag
541 cagctgaggc cattatatga agagtatgtg gtcttgaaaa atgagatggc aagagcaaat
601 cattatgagg actatgggga ttattggaga ggagactatg aagtaaatgg ggtagatggc
661 tatgactaca gccgcggcca gttgattgaa gatgtggaac atacctttga agagattaaa
721 ccattatatg aacatcttca tgcctatgtg agggcaaagt tgatgaatgc ctatccttcc
781 tatatcagtc caattggatg cctccctgct catttgcttg gtgatatgtg gggtagattt
841 tggacaaatc tgtactcttt gacagttccc tttggacaga aaccaaacat agatgttact
901 gatgcaatgg tggaccaggc ctgggatgca cagagaatat tcaaggaggc cgagaagttc
961 tttgtatctg ttggtcttcc taatatgact caaggattct gggaaaattc catgctaacg
1021 gacccaggaa atgttcagaa agcagtctgc catcccacag cttgggacct ggggaagggc
1081 gacttcagga tccttatgtg cacaaaggtg acaatggacg acttcctgac agctcatcat
1141 gagatggggc atatccagta tgatatggca tatgctgcac aaccttttct gctaagaaat
1201 ggagctaatg aaggattcca tgaagctgtt ggggaaatca tgtcactttc tgcagccaca
1261 cctaagcatt taaaatccat tggtcttctg tcacccgatt ttcaagaaga caatgaaaca
1321 gaaataaact tcctgctcaa acaagcactc acgattgttg ggactctgcc atttacttac
1381 atgttagaga agtggaggtg gatggtcttt aaaggggaaa ttcccaaaga ccagtggatg
1441 aaaaagtggt gggagatgaa gcgagagata gttggggtgg tggaacctgt gccccatgat
1501 gaaacatact gtgaccccgc atctctgttc catgtttcta atgattactc attcattcga
1561 tattacacaa ggacccttta ccaattccag tttcaagaag cactttgtca agcagctaaa
1621 catgaaggcc ctctgcacaa atgtgacatc tcaaactcta cagaagctgg acagaaactg
1681 ttcaatatgc tgaggcttgg aaaatcagaa ccctggaccc tagcattgga aaatgttgta
1741 ggagcaaaga acatgaatgt aaggccactg ctcaactact ttgagccctt atttacctgg
1801 ctgaaagacc agaacaagaa ttcttttgtg ggatggagta ccgactggag tccatatgca
1861 gaccaaagca tcaaagtgag gataagccta aaatcagctc ttggagataa agcatatgaa
1921 tggaacgaca atgaaatgta cctgttccga tcatctgttg catatgctat gaggcagtac
1981 tttttaaaag taaaaaatca gatgattctt tttggggagg aggatgtgcg agtggctaat
2041 ttgaaaccaa gaatctcctt taatttcttt gtcactgcac ctaaaaatgt gtctgatatc
2101 attcctagaa ctgaagttga aaaggccatc aggatgtccc ggagccgtat caatgatgct
2161 ttccgtctga atgacaacag cctagagttt ctggggatac agccaacact tggacctcct
2221 aaccagcccc ctgtttccat atggctgatt gtttttggag ttgtgatggg agtgatagtg
2281 gttggcattg tcatcctgat cttcactggg atcagagatc ggaagaagaa aaataaagca
2341 agaagtggag aaaatcctta tgcctccatc gatattagca aaggagaaaa taatccagga
2401 ttccaaaaca ctgatgatgt tcagacctcc ttttagaaaa atctatgttt ttcctcttga
2461 ggtgattttg ttgtatgtaa atgttaattt catggtatag aaaatataag atgataaaga
2521 tatcattaaa tgtcaaaact atgactctgt tcagaaaaaa aattgtccaa agacaacatg
2581 gccaaggaga gagcatcttc attgacattg ctttcagtat ttatttctgt ctctggattt
2641 gacttctgtt ctgtttctta ataaggattt tgtattagag tatattaggg aaagtgtgta
2701 tttggtctca caggctgttc agggataatc taaatgtaaa tgtctgttga atttctgaag
2761 ttgaaaacaa ggatatatca ttggagcaag tgttggatct tgtatggaat atggatggat
2821 cacttgtaag gacagtgcct gggaactggt gtagctgcaa ggattgagaa tggcatgcat
2881 tagctcactt tcatttaatc cattgtcaag gatgacatgc tttcttcaca gtaactcagt
2941 tcaagtacta tggtgatttg cctacagtga tgtttggaat cgatcatgct ttcttcaagg
3001 tgacaggtct aaagagagaa gaatccaggg aacaggtaga ggacattgct ttttcacttc
3061 caaggtgctt gatcaacatc tccctgacaa cacaaaacta gagccagggg cctccgtgaa
3121 ctcccagagc atgcctgata gaaactcatt tctactgttc tctaactgtg gagtgaatgg
3181 aaattccaac tgtatgttca ccctctgaag tgggtaccca gtctcttaaa tcttttgtat
3241 ttgctcacag tgtttgagca gtgctgagca caaagcagac actcaataaa tgctagattt
3301 acacaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//