LOCUS BC035058 4535 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens protein kinase, cAMP-dependent, catalytic, beta, mRNA
(cDNA clone MGC:41879 IMAGE:5262372), complete cds.
ACCESSION BC035058
VERSION BC035058.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4535)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4535)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 73 Row: f Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46909588.
FEATURES Location/Qualifiers
source 1..4535
/db_xref="H-InvDB:HIT000051321"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:41879 IMAGE:5262372"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4535
/gene="PRKACB"
/gene_synonym="MGC41879"
/gene_synonym="MGC9320"
/gene_synonym="PKACB"
/db_xref="GeneID:5567"
/db_xref="HGNC:HGNC:9381"
/db_xref="MIM:176892"
CDS 270..1325
/gene="PRKACB"
/gene_synonym="MGC41879"
/gene_synonym="MGC9320"
/gene_synonym="PKACB"
/codon_start=1
/product="protein kinase, cAMP-dependent, catalytic, beta"
/protein_id="AAH35058.1"
/db_xref="GeneID:5567"
/db_xref="HGNC:HGNC:9381"
/db_xref="MIM:176892"
/translation="MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDF
ERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP
FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLNS
LDIIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNK
AVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSNFSSDLKDLLRNLLQV
DLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE
DIRVSITEKCAKEFGEF"
BASE COUNT 1365 a 848 c 863 g 1459 t
ORIGIN
1 agcgggtctg cccgccgccg ccactgctgc tgccaccgcc gtcgccgccg ccgccgccgc
61 cgccactgct gctgccggtg ctaaggagtt cgctggagcc ctttcctcag acccggcccg
121 gtcttcgcgc ccggactcct ggcgccagcg ctaggcgcac tcaccgctct gacgggtgca
181 gacgcgggag ttgtcccaga ctgtggagtg gcgggcacgg ccccagctcc ccttccgttc
241 cctgacccct tcttgccatc gccccagaca tggggaacgc ggcgaccgcc aagaaaggca
301 gcgaggtgga gagcgtgaaa gagtttctag ccaaagccaa agaagacttt ttgaaaaaat
361 gggagaatcc aactcagaat aatgccggac ttgaagattt tgaaaggaaa aaaacccttg
421 gaacaggttc atttggaaga gtcatgttgg taaaacacaa agccactgaa cagtattatg
481 ccatgaagat cttagataag cagaaggttg ttaaactgaa gcaaatagag catactttga
541 atgagaaaag aatattacag gcagtgaatt ttcctttcct tgttcgactg gagtatgctt
601 ttaaggataa ttctaattta tacatggtta tggaatatgt ccctgggggt gaaatgtttt
661 cacatctaag aagaattgga aggttcagtg agccccatgc acggttctat gcagctcaga
721 tagtgctaac attcgagtac ctcaattcac tagacatcat ctacagagat ctaaaacctg
781 aaaatctctt aattgaccat caaggctata tccaggtcac agactttggg tttgccaaaa
841 gagttaaagg cagaacttgg acattatgtg gaactccaga gtatttggct ccagaaataa
901 ttctcagcaa gggctacaat aaggcagtgg attggtgggc attaggagtg ctaatctatg
961 aaatggcagc tggctatccc ccattctttg cagaccaacc aattcagatt tatgaaaaga
1021 ttgtttctgg aaaggtccga ttcccatcca acttcagttc agatctcaag gaccttctac
1081 ggaacctgct gcaggtggat ttgaccaaga gatttggaaa tctaaagaat ggtgtcagtg
1141 atataaaaac tcacaagtgg tttgccacga cagattggat tgctatttac cagaggaagg
1201 ttgaagctcc attcatacca aagtttagag gctctggaga taccagcaac tttgatgact
1261 atgaagaaga agatatccgt gtctctataa cagaaaaatg tgcaaaagaa tttggtgaat
1321 tttaaagagg aacaagatga catctgagct cacactcagt gtttgcactc tgttgagaga
1381 taaggtagag ctgagaccgt ccttgttgaa gcagttacct agttccttca ttccaacgac
1441 tgagtgaggt ctttattgcc atcatcccgt gtgcgcactc tgcatccacc tatgtaacaa
1501 ggcaccgcta agcaagcatt gtctgtgcca taacacagta ctagaccact ttcttacttc
1561 tctttgggtt gtctttctcc tctcctatat ccatttcttc cttttccaat ttcattggtt
1621 ttctctaaac agtgctccat tttattttgt tggtgtttca gatgggcagt gttatggcta
1681 cgtgatattt gaagggaagg ataagtgttg ctttcagtag ttattgccaa tattgttgtt
1741 ggtcaatggc ttgaagataa actttctaat aattattatt tctttgagta gctcagactt
1801 ggttttgcca aaactcttgg taatttttga agatagactg tcttatcacc aaggaaattt
1861 atacaaatta agactaactt tcttggaatt cactattctg gcaataaatt ttggtagact
1921 aatacagtac agctagaccc agaaatttgg aaggctgtag atcagaggtt ctagttccct
1981 ttccctcctt ttatatcctc ctctccttga gtaatgaagt gaccagcctg tgtagtgtga
2041 caaacgtgtc tcattcagca ggaaaaacta atgatatgga tcatcaccca gattctctca
2101 cttggtacca gcatttctgt aggtattaga gaagagttct aagttttcta aaccttaact
2161 gttccttaag gattttagcc agtattttaa tagaacatga ttaatgaaag tgacaaattt
2221 taaattttct ctaatagtcc tcatcataaa ctttttaaag gaaaataagc aaactaaaaa
2281 gaacattggt ttagataaat acttatactt tgcaaagtca aaaatggctt gatttttgga
2341 aacaatatag aggtattcat atttaaatga gggtttacat ttgttttgtt ttgtaaccgt
2401 taaaaagaag ttgtttccag ctaattattg tggtgtacta tatttgtgag cctagggtag
2461 gggcactgct gcaacttctg ctttcatccc atgcctcatc aatgaggaaa gggaacaaag
2521 tgtataaaac tgccacaatt gtattttaat tttgaggtat gatattttca gatatttcat
2581 aatttctaac ctctgttctc tcagtaaaca gaatgtctga tcgatcatgc agatacaatg
2641 ttggtatttg agaggttagt ttttttccta cacttttttt tgccaactga cttaacaaca
2701 ttgctgtcag gtggaaattt caagcacttt tgcacattta gttcagtgtt tgttgagaat
2761 ccatggctta acccacttgt tttgctattt ttttctttgc ttttaatttt ccccatctga
2821 ttttatctct gcgtttcagt gacctacctt aaaacaacac acgagaagag ttaaactggg
2881 ttcattttaa tgatcaattt acctgcatat aaaatttatt tttaatcaag ctgatcttaa
2941 tgtatataat cattctattt gctttattat cggtgcaggt aggtcattaa caccacttct
3001 tttcatctgt accacaccct ggtgaaacct ttgaagacat aaaaaaaacc tgtctgagat
3061 gttctttcta ccaatctata tgtctttcgg ttatcaagtg tttctgcatg gtaatgtcat
3121 gtaaatgctg atattgattt cactggtcca tctatattta aaacgtgcaa gaaaaaaata
3181 aaatactctg ctctagcaag ttttgtgtaa caaaggcata tcgtcatgtt aataaattta
3241 aaacatcatt cgtataaaat attttaattt tcttgtattt catttagacc caagaacatg
3301 ctgaccaatg tgttctatat gtaaactaca aattctatgg tagctttgtt gtatattatt
3361 gtaaaattat tttaataagt catggggatg acaatttgat tattacaatt tagttttcag
3421 taatcaaaaa gatttctatg aattctaaaa aatatttttt tctatgaaat tactagtgcc
3481 cagctgtaga atctacctta ggtagatgat ccctagacat acgttggttt tgagggctat
3541 tcagccattc cattttactc tctatttaaa ggccgtgagc aagcttgtca tgagcaaata
3601 tgtcaaggga gtcaatctct gaccaatcaa gtacactaaa ttagaatatt tttaaagtat
3661 gtaacattcc cagtttcagc cacaatttag ccaagaataa gataaaaact tgaataagaa
3721 gtaagtagca taaatcagta tttaacctaa aattacatat ttgaaacaga agatattatg
3781 ttatgctcag taaataatta agagatggca ttgtgtaaga aggagcccta gactgaaagt
3841 caagacatct gaatttcagg ctggaaaact atcagtatga tctcagcctc agttctcttg
3901 tctgtaagat ggaagaactg gattaggcag tttgtaagat tcctcctaac tttcacagtc
3961 gatgacaaga ttgtcttttt atctgatatt ttgaagggta tattgctttg aagtaagtct
4021 caataaggca atatatttta gggcatcttt cttcttatct ctgacagtgt tcttaaaatt
4081 atttgaatat cataagagcc ttggtgtctg tcctaattcc tttctcactc accgatgctg
4141 aatacccagt tgaatcaaac tgtcaaccta ccaaaaacga tattgtggct tatgggtatt
4201 gctgtctcat tcttggtata ttcttgtgtt aactgcccat tggcctgaaa atactcattg
4261 taagcctgaa aaaaaaaatc tttcccactg ttttttctgc ttgttgtaag aatcaaatga
4321 aataatgtat gtgaaagcac cttgtaaact gtaacctatc aatgtaaaat gttaaggtgt
4381 gttgttattt cattaattac ttctttgttt agaatggaat ttcctatgca ctactgtagc
4441 taggaaatgc tgaaaacaac tgtgtttttt aattaatcaa taactgcaaa attaaagtac
4501 cttcaatgga taagacaaca aaaaaaaaaa aaaaa
//