LOCUS BC034535 2330 bp mRNA linear HUM 30-DEC-2006
DEFINITION Homo sapiens keratin 6B, mRNA (cDNA clone MGC:24922 IMAGE:4754558),
complete cds.
ACCESSION BC034535
VERSION BC034535.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2330)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2330)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: James Cleaver, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 29 Row: k Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 17505187.
FEATURES Location/Qualifiers
source 1..2330
/db_xref="H-InvDB:HIT000051181"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:24922 IMAGE:4754558"
/tissue_type="Skin, squamous cell carcinoma"
/clone_lib="NCI_CGAP_Skn4"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene 1..2330
/gene="KRT6B"
/gene_synonym="CK6B"
/gene_synonym="K6B"
/gene_synonym="PC2"
/db_xref="GeneID:3854"
/db_xref="HGNC:HGNC:6444"
/db_xref="MIM:148042"
CDS 49..1743
/gene="KRT6B"
/gene_synonym="CK6B"
/gene_synonym="K6B"
/gene_synonym="PC2"
/codon_start=1
/product="keratin 6B"
/protein_id="AAH34535.1"
/db_xref="GeneID:3854"
/db_xref="HGNC:HGNC:6444"
/db_xref="MIM:148042"
/translation="MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGS
GGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGF
GGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVR
AEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYI
NNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDA
AYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSII
AEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLR
SEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQE
LMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLG
LGGGSSYSYGSGLGVGGGFSSSSGRATGGGLSSVGGGSSTIKYTTTSSSSRKSYKH"
BASE COUNT 561 a 632 c 656 g 481 t
ORIGIN
1 cgcctccagc ctctcacact ctcctaagcc ctctcatctc ctggaaccat ggccagcaca
61 tccaccacca tcaggagcca cagcagcagc cgccggggtt tcagtgccaa ctcagccagg
121 ctccctgggg tcagccgctc tggcttcagc agcatctccg tgtcccgctc caggggcagt
181 ggtggcctgg gtggcgcatg tggaggagct ggctttggca gccgcagtct gtatggcctg
241 gggggctcca agaggatctc cattggaggg ggcagctgtg ccatcagtgg cggctatggc
301 agcagagccg gaggcagcta tggctttggt ggcgccggga gtggatttgg tttcggtggt
361 ggagccggca ttggctttgg tctgggtggt ggagccggcc ttgctggtgg ctttgggggc
421 cctggcttcc ctgtgtgccc ccctggaggc atccaagagg tcactgtcaa ccagagtctc
481 ctgactcccc tcaacctgca aattgacccc gccatccagc gggtgcgggc cgaggagcgt
541 gagcagatca agaccctcaa caacaagttt gcctccttca tcgacaaggt gcggttccta
601 gagcagcaga acaaggttct ggacaccaag tggaccctgc tgcaggagca gggcaccaag
661 actgtgaggc agaacctgga gccgttgttc gagcagtaca tcaacaacct caggaggcag
721 ctggacaaca tcgtggggga acggggtcgt ctggactcgg agctgagaaa catgcaggac
781 ctggtggagg acctcaagaa caaatatgag gatgaaatca acaagcgcac agcagcagag
841 aatgaatttg tgactctgaa gaaggatgtg gatgctgcct acatgaacaa ggttgaactg
901 caagccaagg cagacactct tacagatgag atcaacttcc tgagagcctt gtatgatgca
961 gagctgtccc agatgcagac ccacatctca gacacatccg tggtgctatc catggacaac
1021 aaccgcaacc tggacctgga cagcatcatc gctgaggtca aggcccaata tgaggagatt
1081 gctcagagga gcagggctga ggctgagtcc tggtaccaga caaagtacga ggagctgcag
1141 atcacagcag gcagacatgg ggacgacctg cgcaacacca agcaggagat tgctgagatc
1201 aaccgcatga tccagaggct gagatctgag atcgaccacg tcaagaagca gtgtgccaac
1261 ctacaggccg ccattgctga tgctgagcag cgtggggaga tggccctcaa ggatgctaag
1321 aacaagctgg aagggctgga ggatgccctg cagaaggcca agcaggacct ggcccggctg
1381 ctgaaggagt accaggagct gatgaacgtc aagctggccc tggatgtgga gatcgccacc
1441 taccgcaagc tgctggaggg cgaggagtgc aggctgaatg gcgaaggcgt tggacaagtc
1501 aacatctctg tagtgcagtc caccgtctcc agtggctatg gcggtgccag cggtgtcggc
1561 agtggcttag gcctgggtgg aggaagcagc tactcctatg gcagtggtct tggcgttgga
1621 ggcggcttta gttccagcag cggcagagcc actgggggtg gcctcagctc tgttggaggc
1681 ggcagttcca ccatcaagta caccaccacc tcctcctcca gcaggaagag ctacaagcac
1741 tgaagtgctg ccgccagctc tcagtcccac agctctcagg cccctctctg gcagcagagc
1801 cctctcctca ggttgcttgt cctcccctgg cctccagtct cccctgccct cccgggtaga
1861 gctgggatgc cctcactttt cttctcatca atacctgttc cactgagctc ctgttgctta
1921 ccatcaagtc aacagttatc agcactcaac atgcgaatgt cctttttagt tcccgtatta
1981 ttacaggtat ctgagtctgc cataattctg agaagaaaat gacctatatc cccataagaa
2041 ctgaaactca gtctaggtcc agctgcagat gaggagtcct ctctttaatt gctaaccatc
2101 ctgcccatta tagctacact caggagttct catctgacaa gtcagttgtc ctgatcttct
2161 cttgcagtgt ccctgaatgg caagtgatgt accttctgat gcagtctgca ttcctgcact
2221 gctttctctg ctctctttgc cttcttttgt tctgttgaat aaagcatatt gagaatgtga
2281 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
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