LOCUS BC032374 3744 bp mRNA linear HUM 11-APR-2007
DEFINITION Homo sapiens minichromosome maintenance complex component 6, mRNA
(cDNA clone MGC:40308 IMAGE:5122786), complete cds.
ACCESSION BC032374
VERSION BC032374.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3744)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3744)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 64 Row: d Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33469920.
FEATURES Location/Qualifiers
source 1..3744
/db_xref="H-InvDB:HIT000041517"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:40308 IMAGE:5122786"
/tissue_type="Cervix, carcinoma"
/clone_lib="NIH_MGC_12"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3744
/gene="MCM6"
/gene_synonym="MCG40308"
/gene_synonym="Mis5"
/gene_synonym="P105MCM"
/db_xref="GeneID:4175"
/db_xref="HGNC:HGNC:6949"
/db_xref="MIM:601806"
CDS 56..2521
/gene="MCM6"
/gene_synonym="MCG40308"
/gene_synonym="Mis5"
/gene_synonym="P105MCM"
/codon_start=1
/product="minichromosome maintenance complex component 6"
/protein_id="AAH32374.1"
/db_xref="GeneID:4175"
/db_xref="HGNC:HGNC:6949"
/db_xref="MIM:601806"
/translation="MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEI
KYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRK
EIPLAKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLD
CQTVIRDVEQQFKYTQPNICRNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRG
SIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGY
ETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEW
EKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINV
CIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALM
LADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISG
HYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRV
YSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRITVRQLESM
IRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVDEGAGG
INGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEYCRISNLIVLHLRKVEEEEDE
SALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVIHRLTHYDHVLIELTQAGLKGS
TEGSESYEEDPYLVVNPNYLLED"
BASE COUNT 1098 a 737 c 875 g 1034 t
ORIGIN
1 ccacgcgtcc ggtggcggtc gagcgtggcg taggcgaatc ctcggcacta agcatatgga
61 cctcgcggcg gcagcggagc cgggcgccgg cagccagcac ctggaggtcc gcgacgaggt
121 ggccgagaag tgccagaaac tgttcctgga cttcttggag gagtttcaga gcagcgatgg
181 agaaattaaa tacttgcaat tagcagagga actgattcgt cctgagagaa acacattggt
241 tgtgagtttt gtggacctgg aacaatttaa ccagcaactt tccaccacca ttcaagagga
301 gttctataga gtttaccctt acctgtgtcg ggccttgaaa acattcgtca aagaccgtaa
361 agagatccct cttgccaagg atttttatgt tgcattccaa gacctgccta ccagacacaa
421 gattcgagag ctcacctcat ccagaattgg tttgctcact cgcatcagtg ggcaggtggt
481 gcggactcac ccagttcacc cagagcttgt gagcggaact tttctgtgct tggactgtca
541 gacagtgatc agggatgtag aacagcagtt caaatacaca cagccaaaca tctgccgaaa
601 tccagtttgt gccaacagga ggagattctt actggataca aataaatcaa gatttgttga
661 ttttcaaaag gttcgtattc aagagaccca agctgagctt cctcgaggga gtatcccccg
721 cagtttagaa gtaattttaa gggctgaagc tgtggaatca gctcaagctg gtgacaagtg
781 tgactttaca gggacactga ttgttgtgcc tgacgtctcc aagcttagca caccaggagc
841 acgtgcagaa actaattccc gtgtcagtgg tgttgatgga tatgagacag aaggcattcg
901 aggactccgg gcccttggtg ttagggacct ttcttatagg ctggtctttc ttgcctgctg
961 tgttgcgcca accaacccaa ggtttggggg gaaagagctc agagatgagg aacagacagc
1021 tgagagcatt aagaaccaaa tgactgtgaa agaatgggag aaagtgtttg agatgagtca
1081 agataaaaat ctataccaca atctttgtac cagcctgttc cctactatac atggcaatga
1141 tgaagtaaaa cggggtgtcc tgctgatgct ctttggtggc gttccaaaga caacaggaga
1201 agggacctct cttcgagggg acataaatgt ttgcattgtt ggtgacccaa gtacagctaa
1261 gagccaattt ctcaagcacg tggaggagtt cagccccaga gctgtctaca ccagtggtaa
1321 agcgtccagt gctgctggct taacagcagc tgttgtgaga gatgaagaat ctcatgagtt
1381 tgtcattgag gctggagctt tgatgttggc tgataatggt gtgtgttgta ttgatgaatt
1441 tgataagatg gacgtgcggg atcaagttgc tattcatgaa gctatggaac agcagaccat
1501 atccatcact aaagcaggag tgaaggctac tctgaacgcc cggacgtcca ttttggcagc
1561 agcaaaccca atcagtggac actatgacag atcaaaatca ttgaaacaga atataaattt
1621 gtcagctccc atcatgtccc gattcgatct cttctttatc cttgtggatg aatgtaatga
1681 ggttacagat tatgccattg ccaggcgcat agtagatttg cattcaagaa ttgaggaatc
1741 aattgatcgt gtctattccc tcgatgatat cagaagatat cttctctttg caagacagtt
1801 taaacccaag atttccaaag agtcagagga cttcattgtg gagcaatata aacatctccg
1861 ccagagagat ggttctggag tgaccaagtc ttcatggagg attacagtgc gacagcttga
1921 gagcatgatt cgtctctctg aagctatggc tcggatgcac tgctgtgatg aggtccaacc
1981 taaacatgtg aaggaagctt tccggttact gaataaatca atcatccgtg tggaaacacc
2041 tgatgtcaat ctagatcaag aggaagagat ccagatggag gtagatgagg gtgccggtgg
2101 catcaatggt catgctgaca gccctgctcc tgtgaacggg atcaatggct acaatgaaga
2161 cataaatcaa gagtctgctc ccaaagcctc cttaaggctg ggcttctctg agtactgccg
2221 aatctctaac cttattgtgc ttcacctcag aaaggtggaa gaagaagagg acgagtcagc
2281 attaaagagg agcgagcttg ttaactggta cttgaaggaa atcgaatcag agatagactc
2341 tgaagaagaa cttataaata aaaaaagaat catagagaaa gttattcatc gactcacaca
2401 ctatgatcat gttctaattg agctcaccca ggctggattg aaaggctcca cagagggaag
2461 tgagagctat gaagaagatc cctacttggt agttaaccct aactacttgc tcgaagattg
2521 agatagtgaa agtaactgac cagagctgag gaactgtggc acagcacctc gtggcctgga
2581 gcctggctgg agctctgcta gggacagaag tgtttctgga agtgatgctt ccaggatttg
2641 ttttcagaaa caagaattga gttgatggtc ctatgtgtca cattcatcac aggtttcata
2701 ccaacacagg cttcagcact tcctttggtg tgtttcctgt cccagtgaag ttggaaccaa
2761 ataatgtgta gtctctataa ccaatacctt tgttttcatg tgtaagaaaa ggcccattac
2821 ttttaaggta tgtgctgtcc tattgagcaa ataacttttt ttcaattgcc agctactgct
2881 tttattcatc aaaataaaat aacttgttct gaagttgtct attggatttc tttctactgt
2941 accctgatta ttacttccat ctacttctga atgtgagact ttcccttttt gcttaacctg
3001 gagtgaagag gtagaactgt ggtattatgg atgaggtttc tatgagaagg agtcattaga
3061 gaactcatat gaaagctaga ggccttagag atgactttcc aaggttaatt ccagtttttt
3121 ttttttttaa gtttataaaa gtttattata cttttttaaa attactcttt agtaatttat
3181 tttacttctg tgtcctaagg gtaatttctc aggattgttt tcaaattgct tttttagggg
3241 aaataggtca tttgctatat tacaagcaat ccccaaattt tatggtcttc caggaaaagt
3301 tattaccgtt tatgatacta acagttcctg agacttagct atgatcagta tgttcatgag
3361 gtggagcagt tcctgtgttg cagcttttaa caacagatgg cattcattaa atcacaaagt
3421 atgttaaagg tcacaaaagc aaaataactg tctgaggcta aggcccacgt gggacagtct
3481 aatacccatg agtactcaac ttgccttgat gtctgagctt tccagtgcaa tgtgaatttg
3541 agcagccaga aatctattag tagaaagcaa gacagattaa tataggttaa aacaatgatt
3601 taaatatgtt tctcccaata attatctctt tccctggaat caacttgtat gaaaccttgt
3661 caaaatgtac tccacaagta tgtacaatta agtattttaa aaataaatgg caaacattaa
3721 aaaaaaaaaa aaaaaaaaaa aaaa
//