LOCUS BC028157 1791 bp mRNA linear HUM 15-JUL-2006 DEFINITION Homo sapiens polymerase (RNA) II (DNA directed) polypeptide C, 33kDa, mRNA (cDNA clone MGC:40083 IMAGE:5240953), complete cds. ACCESSION BC028157 VERSION BC028157.1 KEYWORDS MGC. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 1791) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. CONSRTM Mammalian Gene Collection Program Team TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 1791) CONSRTM NIH MGC Project TITLE Direct Submission JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov COMMENT Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: Life Technologies, Inc. cDNA Library Preparation: Life Technologies, Inc. cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: National Institutes of Health Intramural Sequencing Center (NISC), Gaithersburg, Maryland; Web site: http://www.nisc.nih.gov/ Contact: nisc_mgc@nhgri.nih.gov Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B., Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S., Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P., Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R., Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C., McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W., Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L., Young,A., Zhang,L.-H. and Green,E.D. Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAK Plate: 62 Row: l Column: 9 This clone was selected for full length sequencing because it passed the following selection criteria: Similarity but not identity to protein. FEATURES Location/Qualifiers source 1..1791 /db_xref="H-InvDB:HIT000040468" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /clone="MGC:40083 IMAGE:5240953" /tissue_type="Brain, fetal, whole pooled" /clone_lib="NIH_MGC_121" /lab_host="DH10B" /note="Vector: pCMV-SPORT6" gene 1..1791 /gene="POLR2C" /gene_synonym="hRPB33" /gene_synonym="hsRPB3" /gene_synonym="RPB3" /gene_synonym="RPB31" /db_xref="GeneID:5432" /db_xref="HGNC:HGNC:9189" /db_xref="MIM:180663" CDS 43..870 /gene="POLR2C" /gene_synonym="hRPB33" /gene_synonym="hsRPB3" /gene_synonym="RPB3" /gene_synonym="RPB31" /codon_start=1 /product="polymerase (RNA) II (DNA directed) polypeptide C, 33kDa" /protein_id="AAH28157.1" /db_xref="GeneID:5432" /db_xref="HGNC:HGNC:9189" /db_xref="MIM:180663" /translation="MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPI IAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFT LDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELR LRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQA PYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN" BASE COUNT 468 a 441 c 451 g 431 t ORIGIN 1 tcaccgcgga gcagacgcgg aggctggtgg cccctgggcg agatgccgta cgccaaccag 61 cctaccgtgc ggatcacgga gctcactgac gagaatgtca agttcatcat cgagaacacc 121 gacctggcgg tggccaattc gattcggagg gtcttcatcg ctgaggttcc cataatagcc 181 attgactggg ttcagattga tgccaattcc tcagtccttc atgatgaatt cattgctcac 241 aggcttggat taattcccct cattagtgat gacattgtgg acaagctgca gtactctcgg 301 gactgcacat gtgaggagtt ctgccccgag tgctcggtgg agttcaccct cgatgtgcgg 361 tgcaatgaag accagacgcg acatgtcacg tctcgagacc tcatctccaa cagcccccgg 421 gtcattccgg tgacatcccg gaaccgagat aatgacccca atgactacgt ggagcaggat 481 gacatcctca tcgtcaagtt gagaaagggc caggagctga gacttcgagc ctatgccaaa 541 aagggctttg gcaaggagca tgccaagtgg aaccctactg caggggtggc ttttgaatac 601 gatccagaca atgccctgag gcacacagtg taccccaagc ccgaggaatg gccaaagagt 661 gagtactcgg agctggatga ggatgagtcg caggctccct atgaccccaa cggcaagcca 721 gaaaggtttt actacaatgt ggagtcctgt ggctctctgc gtcctgaaac cattgtcctg 781 tcagccctct caggattgaa gaagaaactg agtgatttac aaactcaatt aagccacgag 841 atccagagtg atgtgctaac cataaattaa ctgcagcttg cctgcttcag caaaaacgga 901 gattcaggcc agcagctgga tatgggggtc tctcttcaga ctcttctcgt ttctgagaat 961 ctagtctact gttggttgag cttcttggca ggacatcagt accaactaga agtgggtcat 1021 agatagatta ccagggatgc agtggtgttt aggcaggata ggtctttact ggccctgact 1081 gctgttaata attggcagca gtgctcccca gatcccagaa ggtccctgct ggagtgtttc 1141 cagtgcacct gtagggaacc aactagactt ctctcctggt tagtccagct ctttactcta 1201 aaccctttct gtccaaaatg agtcattttc agttgtacct tagatgtctg gtgttgagga 1261 tcaagtgcca tagcctttat tcagggggcc tataaaccct tccagttctt gccccagggc 1321 tggcctgcta gcgcttcaaa ttcccaggtg tccctaattt gagaagtaac cttttggaat 1381 agcattagac cctggctgtc ccctccccac caaataaaca tgatatttca ttctctgtcc 1441 agcagtcatg aaccccttca cctccaatga cctgatcatt tagtttggtg ggggtggggg 1501 tgggggtggg ggtgggggtg gaagcagccg caggagcaag ggcccctccc acatacacag 1561 gaggagtatt tcatttctcc ttaatgaagg ctctggccct aacccctcag cactgtctcc 1621 agataggaac atgcacaaag cagttaatta ggcagcctgg agaaaaccag agatccagta 1681 cagaaaggaa aggatattta ttgattaaca gaagttgtct ttttaaaagt gtttattttt 1741 ggcaataaag agcacaacat aatctcaaaa aaaaaaaaaa aaaaaaaaaa a //