LOCUS       BC025979                2373 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens protein arginine methyltransferase 5, mRNA (cDNA clone
            MGC:15219 IMAGE:3833019), complete cds.
ACCESSION   BC025979
VERSION     BC025979.2
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2373)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 2373)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAR-2002) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     On Dec 9, 2003 this sequence version replaced BC025979.1.
            Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: ATCC/DCTD/DTP
            cDNA Library Preparation: Rubin Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Institute for Systems Biology
            http://www.systemsbiology.org
            contact: amadan@systemsbiology.org
            Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
            Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 24 Row: p Column: 8.
FEATURES             Location/Qualifiers
     source          1..2373
                     /db_xref="H-InvDB:HIT000040048"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:15219 IMAGE:3833019"
                     /tissue_type="Skin, melanotic melanoma."
                     /clone_lib="NIH_MGC_20"
                     /lab_host="DH10B-R"
                     /note="Vector: pOTB7"
     gene            1..2373
                     /gene="PRMT5"
                     /gene_synonym="IBP72"
                     /gene_synonym="JBP1"
                     /gene_synonym="SKB1Hs"
                     /db_xref="GeneID:10419"
                     /db_xref="HGNC:HGNC:10894"
                     /db_xref="MIM:604045"
     CDS             13..1926
                     /gene="PRMT5"
                     /gene_synonym="IBP72"
                     /gene_synonym="JBP1"
                     /gene_synonym="SKB1Hs"
                     /codon_start=1
                     /product="protein arginine methyltransferase 5"
                     /protein_id="AAH25979.1"
                     /db_xref="GeneID:10419"
                     /db_xref="HGNC:HGNC:10894"
                     /db_xref="MIM:604045"
                     /translation="MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMP
                     VFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRN
                     SEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAP
                     EDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVI
                     DRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKE
                     FCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKY
                     SQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVE
                     KNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECL
                     DGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHN
                     FHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLS
                     IRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSA
                     IHNPTGRSYTIGL"
BASE COUNT          640 a          583 c          595 g          555 t
ORIGIN      
        1 gcgaggagaa agatggcggc gatggcggtc gggggtgctg gtgggagccg cgtgtccagc
       61 gggagggacc tgaattgcgt ccccgaaata gctgacacac taggggctgt ggccaagcag
      121 gggtttgatt tcctctgcat gcctgtcttc catccgcgtt tcaagaggga gttcattcag
      181 gaacctgcta agaatcggcc cggtccccag acacgatcag acctactgct gtcaggaagg
      241 gactggaata cgctaattgt gggaaagctt tctccatgga ttcgtccaga ctcaaaagtg
      301 gagaagattc gcaggaactc cgaggcggcc atgttacagg agctgaattt tggtgcatat
      361 ttgggtcttc cagctttcct gctgcccctt aatcaggaag ataacaccaa cctggccaga
      421 gttttgacca accacatcca cactggccat cactcttcca tgttctggat gcgggtaccc
      481 ttggtggcac cagaggacct gagagatgat ataattgaga atgcaccaac tacacacaca
      541 gaggagtaca gtggggagga gaaaacgtgg atgtggtggc acaacttccg gactttgtgt
      601 gactatagta agaggattgc agtggctctt gaaattgggg ctgacctccc atctaatcat
      661 gtcattgatc gctggcttgg ggagcccatc aaagcagcca ttctccccac tagcattttc
      721 ctgaccaata agaagggatt tcctgttctt tctaagatgc accagaggct catcttccgg
      781 ctcctcaagt tggaggtgca gttcatcatc acaggcacca accaccactc agagaaggag
      841 ttctgctcct acctccaata cctggaatac ttaagccaga accgtcctcc acctaatgcc
      901 tatgaactct ttgccaaggg ctatgaagac tatctgcagt ccccgcttca gccactgatg
      961 gacaatctgg aatctcagac atatgaagtg tttgaaaagg accccatcaa atactctcag
     1021 taccagcagg ccatctataa atgtctgcta gaccgagtac cagaagagga gaaggatacc
     1081 aatgtccagg tactgatggt gctgggagca ggacggggac ccctggtgaa cgcttccctg
     1141 cgggcagcca agcaggccga ccggcggata aagctgtatg ctgtggagaa aaacccaaat
     1201 gccgtggtga cgctagagaa ctggcagttt gaagaatggg gaagccaagt gaccgtagtc
     1261 tcatcagaca tgagggaatg ggtggctcca gagaaagcag acatcattgt cagtgagctt
     1321 ctgggctcat ttgctgacaa tgaattgtcg cctgagtgcc tggatggagc ccagcacttc
     1381 ctaaaagatg atggtgtgag catccccggg gagtacactt cctttctggc tcccatctct
     1441 tcctccaagc tgtacaatga ggtccgagcc tgtagggaga aggaccgtga ccctgaggcc
     1501 cagtttgaga tgccttatgt ggtacggctg cacaacttcc accagctctc tgcaccccag
     1561 ccctgtttca ccttcagcca tcccaacaga gatcctatga ttgacaacaa ccgctattgc
     1621 accttggaat ttcctgtgga ggtgaacaca gtactacatg gctttgccgg ctactttgag
     1681 actgtgcttt atcaggacat cactctgagt atccgtccag agactcactc tcctgggatg
     1741 ttctcatggt ttcccatcct cttccctatt aagcagccca taacggtacg tgaaggccaa
     1801 accatctgtg tgcgtttctg gcgatgcagc aattccaaga aggtgtggta tgagtgggct
     1861 gtgacagcac cagtctgttc tgctattcat aaccccacag gccgctcata taccattggc
     1921 ctctagccct gcgtgccaag tgtccagagc cttggaagca gcttcaggtt ctgctcctgt
     1981 agtacagaag gtgcagtaca tctatgggct gtgattcccc ttgcccatca gagaggagca
     2041 tttcaatctg ctttcctgcc ttacatcaag gtgggcaagg gattataatt aattgcaggg
     2101 ctcaagccac caatctatga agacctcagg ccaaggggtg aggaattagt gctggatttg
     2161 aagctacgca ctcagcctca agaactccct ggaatatccc tgagaacatg gggtttgaac
     2221 ggattttcag cctttttctg ttgttgtttt gatggttttg tgtaagagga aatacaaata
     2281 aagttatagc cctttactgc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2341 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//