LOCUS BC025362 1726 bp mRNA linear HUM 02-MAR-2004
DEFINITION Homo sapiens amine oxidase (flavin containing) domain 2, mRNA (cDNA
clone IMAGE:5013430), partial cds.
ACCESSION BC025362
VERSION BC025362.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1726)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1726)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (05-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 42 Row: l Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..1726
/db_xref="H-InvDB:HIT000091064"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5013430"
/tissue_type="Brain, astrocytoma, grade IV"
/clone_lib="NIH_MGC_98"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene <1..1726
/gene="AOF2"
/gene_synonym="BHC110"
/gene_synonym="KIAA0601"
/db_xref="GeneID:23028"
CDS <1..1373
/gene="AOF2"
/gene_synonym="BHC110"
/gene_synonym="KIAA0601"
/codon_start=3
/product="AOF2 protein"
/protein_id="AAH25362.1"
/db_xref="GeneID:23028"
/translation="DFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEE
LKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELA
ETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDD
DFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTF
IYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWD
PSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAI
LKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPG
APQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQATPGVPA
QQSPSM"
misc_feature 384..1289
/gene="AOF2"
/gene_synonym="BHC110"
/gene_synonym="KIAA0601"
/note="Amino_oxidase; Region: Flavin containing amine
oxidoreductase. This family consists of various amine
oxidases, including maze polyamine oxidase (PAO) and
various flavin containing monoamine oxidases (MAO). The
aligned region includes the flavin binding site of these
enzymes. The family also contains phytoene dehydrogenases
and related enzymes. In vertebrates MAO plays an important
role regulating the intracellular levels of amines via
there oxidation"
/db_xref="CDD:pfam01593"
BASE COUNT 490 a 376 c 417 g 443 t
ORIGIN
1 tagacttcaa tgtcctcaat aataagcctg tgtcccttgg ccaggcattg gaagttgtca
61 ttcagttaca agagaagcat gtcaaagatg agcagattga acattggaag aagatagtga
121 aaactcagga agaattgaaa gaacttctta ataagatggt aaatttgaaa gagaaaatta
181 aagaactcca tcagcaatac aaagaagcat ctgaagtaaa gccacccaga gatattactg
241 ccgagttctt agtgaaaagc aaacacaggg atctgaccgc cctatgcaag gaatatgatg
301 aattagctga aacacaagga aagctagaag aaaaacttca ggagttggaa gcgaatcccc
361 caagtgatgt atatctctca tcaagagaca gacaaatact tgattggcat tttgcaaatc
421 ttgaatttgc taatgccaca cctctctcaa ctctctccct taagcactgg gatcaggatg
481 atgactttga gttcactggc agccacctga cagtaaggaa tggctactcg tgtgtgcctg
541 tggctttagc agaaggccta gacattaaac tgaatacagc agtgcgacag gttcgctaca
601 cggcttcagg atgtgaagtg atagctgtga atacccgctc cacgagtcaa acctttattt
661 ataaatgcga cgcagttctc tgtacccttc ccctgggtgt gctgaagcag cagccaccag
721 ccgttcagtt tgtgccacct ctccctgagt ggaaaacatc tgcagtccaa aggatgggat
781 ttggcaacct taacaaggtg gtgttgtgtt ttgatcgggt gttctgggat ccaagtgtca
841 atttgttcgg gcatgttggc agtacgactg ccagcagggg tgagctcttc ctcttctgga
901 acctctataa agctccaata ctgttggcac tagtggcagg agaagctgct ggtatcatgg
961 aaaacataag tgacgatgtg attgttggcc gatgcctggc cattctcaaa gggatttttg
1021 gtagcagtgc agtacctcag cccaaagaaa ctgtggtgtc tcgttggcgt gctgatccct
1081 gggctcgggg ctcttattcc tatgttgctg caggatcatc tggaaatgac tatgatttaa
1141 tggctcagcc aatcactcct ggcccctcga ttccaggtgc cccacagccg attccacgac
1201 tcttctttgc gggagaacat acgatccgta actacccagc cacagtgcat ggtgctctgc
1261 tgagtgggct gcgagaagcg ggaagaattg cagaccagtt tttgggggcc atgtatacgc
1321 tgcctcgcca ggccacacca ggtgttcctg cacagcagtc cccaagcatg tgagacagat
1381 gcattctaag ggaagaggcc catgtgcctg tttctgccat gtaaggaagg ctcttctagc
1441 aatactagat cccactgaga aaatccaccc tggcatctgg gctcctgatc agctgatgga
1501 gctcctgatt tgacaaagga gcttgcctcc tttgaatgac ctagagcaca gggaggaact
1561 tgtccattag tttggaattg tgttcttcgt aaagactgag gcaagcaagt gctgtgaaat
1621 aacatcatct tagtcccttg gtgtgtgggg tttttgtttt ttttttatat tttgagaata
1681 aaacttcata taaaattgaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//