LOCUS BC022244 1757 bp mRNA linear HUM 06-OCT-2003
DEFINITION Homo sapiens pyrroline-5-carboxylate reductase 1, mRNA (cDNA clone
MGC:22061 IMAGE:4420238), complete cds.
ACCESSION BC022244
VERSION BC022244.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1757)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1757)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 27 Row: j Column: 7.
FEATURES Location/Qualifiers
source 1..1757
/db_xref="H-InvDB:HIT000039424"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22061 IMAGE:4420238"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1757
/gene="PYCR1"
/gene_synonym="P5C"
/gene_synonym="P5CR"
/gene_synonym="PP222"
/gene_synonym="PYCR"
/db_xref="GeneID:5831"
/db_xref="MIM:179035"
CDS 406..921
/gene="PYCR1"
/gene_synonym="P5C"
/gene_synonym="P5CR"
/gene_synonym="PP222"
/gene_synonym="PYCR"
/codon_start=1
/product="PYCR1 protein"
/protein_id="AAH22244.1"
/db_xref="GeneID:5831"
/db_xref="MIM:179035"
/translation="MEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGG
VKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGF
RSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKL
LPRSLAPAGKD"
misc_feature 406..720
/gene="PYCR1"
/gene_synonym="P5C"
/gene_synonym="P5CR"
/gene_synonym="PP222"
/gene_synonym="PYCR"
/note="Region: Delta 1-pyrroline-5-carboxylate reductase"
/db_xref="CDD:pfam01089"
BASE COUNT 351 a 558 c 505 g 343 t
ORIGIN
1 gccctggcca agggcttcac agcagcaggc gtcttggctg cccacaagat aatggctagc
61 tccccagaca tggacctggc cacagtttct gctctcagga agatgggggt gaagttgaca
121 ccccacaaca aggagacggt gcagcacagt gatgtgctct tcctggctgt gaagccacac
181 atcatcccct tcatcctgga tgaaataggc gccgacattg aggacagaca cattgtggtg
241 tcctgcgcgg ccggcgtcac catcagctcc attgagaaga agctgtcagc gtttcggcca
301 gcccccaggg tcatccgctg catgaccaac actccagtcg tggtgcggga gggggccacc
361 gtgtatgcca caggcacgca cgcccaggtg gaggacggga ggctcatgga gcagctgctg
421 agcagcgtgg gcttctgcac ggaggtggaa gaggacctga ttgatgccgt cacggggctc
481 agtggcagcg gccccgccta cgcattcaca gccctggatg ccctggctga tgggggtgtg
541 aagatgggac ttccaaggcg cctggcagtc cgcctcgggg cccaggccct cctgggggct
601 gccaagatgc tgctgcactc agaacagcac ccaggccagc tcaaggacaa cgtcagctct
661 cctggtgggg ccaccatcca tgccttgcat gtgctggaga gtgggggctt ccgctccctg
721 ctcatcaacg ctgtggaggc ctcctgcatc cgcacacggg agctgcagtc catggctgac
781 caggagcagg tgtcaccagc cgccatcaag aagaccatcc tggacaaggt gaagctggac
841 tcccctgcag ggaccgctct gtcgccttct ggccacacca agctgctccc ccgcagcctg
901 gccccagcgg gcaaggattg acacgtcctg cctgaccacc atcctgccac caccttctct
961 tctcttgtca ctagggggac tagggggtcc ccaaagtggc ccactttctg tggctctgat
1021 cagcgcaggg gccagccagg gacatagcca gggaggggcc acatcacttc ccactggaaa
1081 tctctgtggt ctgcaagtgc ttcccagccc agaacagggg tggattcccc aacctcaacc
1141 tcctttcttc tctgctccca aaccatgtca ggaccacctt cctctagagc tcgggagccc
1201 ggagggtctt cacccactcc tactccagta tcagctggca cgggctcctt cctgagagca
1261 aaggtcaagg accccctctg tgaaggctca gcagaggtgg gatcccacgc cccctcccgg
1321 cccctccctg ccctccattc agggagaaac ctctccttcc cgtgtgagaa gggccagagg
1381 gtccaggcat cccaagtcca gcgtgaaggg ccacagcccc tcttggctgc caagcacgca
1441 gatcccatgg acatttgggg aaagggctcc ttgggctgct ggtgaacttc tgtggccacc
1501 acctcctgct cctgacctcc ctgggagggt gctatcagtt ctgtcctggc cctttcagtt
1561 ttataagttg gtttccagcc cccagtgtcc tgacttctgt ctgccacatg aggagggagg
1621 ccctgcctgt gtgggagggt ggttactgtg ggtggaatag tggaggcctt caactgatta
1681 gacaaggccc gcccacatct tggagggcat ctgccttact gattaaaatg tcaatgtaat
1741 ctaaaaaaaa aaaaaaa
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