LOCUS BC019236 1543 bp mRNA linear HUM 21-OCT-2003
DEFINITION Homo sapiens major histocompatibility complex, class I, A, mRNA
(cDNA clone MGC:2384 IMAGE:2821717), complete cds.
ACCESSION BC019236
VERSION BC019236.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1543)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1543)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (10-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC019236.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 2 Row: g Column: 23.
FEATURES Location/Qualifiers
source 1..1543
/db_xref="H-InvDB:HIT000038568_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2384 IMAGE:2821717"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1543
/gene="HLA-A"
/db_xref="GeneID:3105"
/db_xref="MIM:142800"
CDS 6..1103
/gene="HLA-A"
/codon_start=1
/product="HLA-A protein"
/protein_id="AAH19236.1"
/db_xref="GeneID:3105"
/db_xref="MIM:142800"
/translation="MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEP
RFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDL
GTLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRPWTAA
DMAAQTTKHKWEAAHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAV
SDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSG
QEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLFGAVITGAVVAAVMWRR
KSSDRKGGSYSQAASSDSAQGSDVSLTACKV"
misc_feature 78..614
/gene="HLA-A"
/note="MHC_I; Region: Class I Histocompatibility antigen,
domains alpha 1 and 2"
/db_xref="CDD:pfam00129"
misc_feature 669..884
/gene="HLA-A"
/note="IGc1; Region: Immunoglobulin C-Type"
/db_xref="CDD:smart00407"
BASE COUNT 342 a 430 c 464 g 307 t
ORIGIN
1 cgaggatggc cgtcatggcg ccccgaaccc tcgtcctgct actctcgggg gctctggccc
61 tgacccagac ctgggcgggc tctcactcca tgaggtattt cttcacatcc gtgtcccggc
121 ccggccgcgg ggagccccgc ttcatcgcag tgggctacgt ggacgacacg cagttcgtgc
181 ggttcgacag cgacgccgcg agccagagga tggagccgcg ggcgccgtgg atagagcagg
241 agggtccgga gtattgggac ggggagacac ggaaagtgaa ggcccactca cagactcacc
301 gagtggacct ggggaccctg cgcggctact acaaccagag cgaggccggt tctcacaccg
361 tccagaggat gtatggctgc gacgtggggt cggactggcg cttcctccgc gggtaccacc
421 agtacgccta cgacggcaag gattacatcg ccctgaaaga ggacctgcgc ccttggaccg
481 cggcggacat ggcagctcag accaccaagc acaagtggga ggcggcccat gtggcggagc
541 agttgagagc ctacctggag ggcacgtgcg tggagtggct ccgcagatac ctggagaacg
601 ggaaggagac gctgcagcgc acggacgccc ccaaaacgca tatgactcac cacgctgtct
661 ctgaccatga agccaccctg aggtgctggg ccctgagctt ctaccctgcg gagatcacac
721 tgacctggca gcgggatggg gaggaccaga cccaggacac ggagctcgtg gagaccaggc
781 ctgcagggga tggaaccttc cagaagtggg cggctgtggt ggtgccttct ggacaggagc
841 agagatacac ctgccatgtg cagcatgagg gtttgcccaa gcccctcacc ctgagatggg
901 agccgtcttc ccagcccacc atccccatcg tgggcatcat tgctggcctg gttctctttg
961 gagctgtgat cactggagct gtggtcgctg ctgtgatgtg gaggaggaag agctcagata
1021 gaaaaggagg gagctactct caggctgcaa gcagtgacag tgcccagggc tctgatgtgt
1081 ctctcacagc ttgtaaagtg tgagacagct gccttgtgtg ggactgagag gcaagagttg
1141 ttcctgccct tccctttgtg acttgaagaa ccctgacttt gtttctgcaa aggcacctgc
1201 atgtgtctgt gttcgtgtag gcataatgtg aggaggtggg gagaccaccc cacccccatg
1261 tccaccatga ccctcttccc acgctgacct gtgctccctc cccaatcatc tttcctgttc
1321 cagagaggtg gggctgaggt gtctccatct ctgtctcaac ttcatggtgc actgagctgt
1381 aacttcttcc ttccctatta aaattagaac ctgagtataa atttactttc tcaaattctt
1441 gccatgagag gttgatgagt taattaaagg agaagattcc taaaatttga gagacaaaat
1501 aaatggaaca catgagaacc ttccaaaaaa aaaaaaaaaa aaa
//