LOCUS BC018927 1808 bp mRNA linear HUM 22-DEC-2006
DEFINITION Homo sapiens hexosaminidase A (alpha polypeptide), mRNA (cDNA clone
MGC:14125 IMAGE:3353424), complete cds.
ACCESSION BC018927
VERSION BC018927.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1808)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1808)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC018927.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 20 Row: a Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13128865.
FEATURES Location/Qualifiers
source 1..1808
/db_xref="H-InvDB:HIT000038476"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:14125 IMAGE:3353424"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1808
/gene="HEXA"
/gene_synonym="TSD"
/db_xref="GeneID:3073"
/db_xref="HGNC:HGNC:4878"
/db_xref="MIM:606869"
CDS 12..1601
/gene="HEXA"
/gene_synonym="TSD"
/codon_start=1
/product="hexosaminidase A (alpha polypeptide)"
/protein_id="AAH18927.1"
/db_xref="GeneID:3073"
/db_xref="HGNC:HGNC:4878"
/db_xref="MIM:606869"
/translation="MTSSRLWFSLLLAAAFAGRATALWPWPQNFQTSDQRYVLYPNNF
QFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPYLTGKRHTLEKNVLVVSVVTP
GCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTE
IEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTF
PELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTP
CYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPE
IQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVW
REDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQKA
LVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELL
RRGVQAQPLNVGFCEQEFEQT"
BASE COUNT 401 a 473 c 479 g 455 t
ORIGIN
1 accagcgggc catgacaagt tccaggcttt ggttttcgct gctgctggcg gcagcgttcg
61 caggacgggc gacggccctc tggccctggc ctcagaactt ccaaacctcc gaccagcgct
121 acgtccttta cccgaacaac tttcaattcc agtacgatgt cagctcggcc gcgcagcccg
181 gctgctcagt cctcgacgag gccttccagc gctatcgtga cctgcttttc ggttccgggt
241 cttggccccg tccttacctc acagggaaac ggcatacact ggagaagaat gtgttggttg
301 tctctgtagt cacacctgga tgtaaccagc ttcctacttt ggagtcagtg gagaattata
361 ccctgaccat aaatgatgac cagtgtttac tcctctctga gactgtctgg ggagctctcc
421 gaggtctgga gacttttagc cagcttgttt ggaaatctgc tgagggcaca ttctttatca
481 acaagactga gattgaggac tttccccgct ttcctcaccg gggcttgctg ttggatacat
541 ctcgccatta cctgccactc tctagcatcc tggacactct ggatgtcatg gcgtacaata
601 aattgaacgt gttccactgg catctggtag atgatccttc cttcccatat gagagcttca
661 cttttccaga gctcatgaga aaggggtcct acaaccctgt cacccacatc tacacagcac
721 aggatgtgaa ggaggtcatt gaatacgcac ggctccgggg tatccgtgtg cttgcagagt
781 ttgacactcc tggccacact ttgtcctggg gaccaggtat ccctggatta ctgactcctt
841 gctactctgg gtctgagccc tctggcacct ttggaccagt gaatcccagt ctcaataata
901 cctatgagtt catgagcaca ttcttcttag aagtcagctc tgtcttccca gatttttatc
961 ttcatcttgg aggagatgag gttgatttca cctgctggaa gtccaaccca gagatccagg
1021 actttatgag gaagaaaggc ttcggtgagg acttcaagca gctggagtcc ttctacatcc
1081 agacgctgct ggacatcgtc tcttcttatg gcaagggcta tgtggtgtgg caggaggtgt
1141 ttgataataa agtaaagatt cagccagaca caatcataca ggtgtggcga gaggatattc
1201 cagtgaacta tatgaaggag ctggaactgg tcaccaaggc cggcttccgg gcccttctct
1261 ctgccccctg gtacctgaac cgtatatcct atggccctga ctggaaggat ttctacgtag
1321 tggaacccct ggcatttgaa ggtacccctg agcagaaggc tctggtgatt ggtggagagg
1381 cttgtatgtg gggagaatat gtggacaaca caaacctggt ccccaggctc tggcccagag
1441 caggggctgt tgccgaaagg ctgtggagca acaagttgac atctgacctg acatttgcct
1501 atgaacgttt gtcacacttc cgctgtgagt tgctgaggcg aggtgtccag gcccaacccc
1561 tcaatgtagg cttctgtgag caggagtttg aacagacctg agccccaggc accgaggagg
1621 gtgctggctg taggtgaatg gtagtggagc caggcttcca ctgcatcctg gccaggggac
1681 ggagcccctt gccttcgtgc cccttgcctg cgtgcccctg tgcttggaga gaaaggggcc
1741 ggtgctggcg ctcgcattca ataaagagta atgtggcatt tttctataat aaaaaaaaaa
1801 aaaaaaaa
//