LOCUS BC017714 2818 bp mRNA linear HUM 11-SEP-2007
DEFINITION Homo sapiens HNF1 homeobox B, mRNA (cDNA clone MGC:21262
IMAGE:4414015), complete cds.
ACCESSION BC017714
VERSION BC017714.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2818)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2818)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 27 Row: i Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4507396.
FEATURES Location/Qualifiers
source 1..2818
/db_xref="H-InvDB:HIT000038098"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:21262 IMAGE:4414015"
/tissue_type="Liver, adenocarcinoma"
/clone_lib="NIH_MGC_90"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2818
/gene="HNF1B"
/gene_synonym="FJHN"
/gene_synonym="HNF1beta"
/gene_synonym="HNF2"
/gene_synonym="LFB3"
/gene_synonym="MODY5"
/gene_synonym="VHNF1"
/db_xref="GeneID:6928"
/db_xref="HGNC:HGNC:11630"
/db_xref="MIM:189907"
CDS 189..1862
/gene="HNF1B"
/gene_synonym="FJHN"
/gene_synonym="HNF1beta"
/gene_synonym="HNF2"
/gene_synonym="LFB3"
/gene_synonym="MODY5"
/gene_synonym="VHNF1"
/codon_start=1
/product="HNF1 homeobox B"
/protein_id="AAH17714.1"
/db_xref="GeneID:6928"
/db_xref="HGNC:HGNC:11630"
/db_xref="MIM:189907"
/translation="MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPNFGVKLE
TLPLSPGSGAEPDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEE
AAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPM
KTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQSHGPGQ
SDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQR
GVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGS
PHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDPG
HNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNT
SQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQ
NSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMSSSKQCPLQAW"
BASE COUNT 714 a 878 c 666 g 560 t
ORIGIN
1 atcatggcaa gttagaagtt ttctgactcc tttcggagga gcctccggga ccccggggag
61 taacaggtgt ctggaggctg aagggtggag gggttcctgg atttggggtt tgcttgtgaa
121 actcccctcc accctcctct ctcgcaccca cccaccccct cacccccttc tttttccgtc
181 cttggaaaat ggtgtccaag ctcacgtcgc tccagcaaga actcctgagc gccctgctga
241 gctccggggt caccaaggag gtgctggttc aggccttgga ggagttgctg ccatccccga
301 acttcggggt gaagctggag acgctgcccc tgtcccctgg cagcggggcc gagcccgaca
361 ccaagccggt cttccatact ctcaccaacg gccacgccaa gggccgcttg tccggcgacg
421 agggctccga ggacggcgac gactatgaca cacctcccat cctcaaggag ctgcaggcgc
481 tcaacaccga ggaggcggcg gagcagcggg cggaggtgga ccggatgctc agtgaggacc
541 cttggagggc tgctaaaatg atcaagggtt acatgcagca acacaacatc ccccagaggg
601 aggtggtcga tgtcaccggc ctgaaccagt cgcacctctc ccagcatctc aacaagggca
661 cccctatgaa gacccagaag cgtgccgctc tgtacacctg gtacgtcaga aagcaacgag
721 agatcctccg acaattcaac cagacagtcc agagttctgg aaatatgaca gacaaaagca
781 gtcaggatca gctgctgttt ctctttccag agttcagtca acagagccat gggcctgggc
841 agtccgatga tgcctgctct gagcccacca acaagaagat gcgccgcaac cggttcaaat
901 gggggcccgc gtcccagcaa atcttgtacc aggcctacga tcggcaaaag aaccccagca
961 aggaagagag agaggcctta gtggaggaat gcaacagggc agaatgtttg cagcgagggg
1021 tgtccccctc caaagcccac ggcctgggct ccaacttggt cactgaggtc cgtgtctaca
1081 actggtttgc aaaccgcagg aaggaggagg cattccggca aaagctggcc atggacgcct
1141 atagctccaa ccagactcac agcctgaacc ctctgctctc ccacggctcc ccccaccacc
1201 agcccagctc ctctcctcca aacaagctgt caggagtgcg ctacagccag cagggaaaca
1261 atgagatcac ttcctcctca acaatcagtc accatggcaa cagcgccatg gtgaccagcc
1321 agtcggtttt acagcaagtc tccccagcca gcctggaccc aggccacaat ctcctctcac
1381 ctgatggtaa aatgatctca gtctcaggag gaggtttgcc cccagtcagc accttgacga
1441 atatccacag cctctcccac cataatcccc agcaatctca aaacctcatc atgacacccc
1501 tctctggagt catggcaatt gcacaaagcc tcaacacctc ccaagcacag agtgtccctg
1561 tcatcaacag tgtggccggc agcctggcag ccctgcagcc cgtccagttc tcccagcagc
1621 tgcacagccc tcaccagcag cccctcatgc agcagagccc aggcagccac atggcccagc
1681 agcccttcat ggcagctgtg actcagctgc agaactcaca catgtacgca cacaagcagg
1741 aaccccccca gtattcccac acctcccggt ttccatctgc aatggtggtc acagatacca
1801 gcagcatcag tacactcacc aacatgtctt caagtaaaca gtgtcctcta caagcctggt
1861 gatgcccaca caccacttac ttcgtgcgca acaacaagga ccctgttttc cacaccatca
1921 ccctctgggc agctgtcatg gaaaagccca gtgacctgac cagcacctgc gagaggtccc
1981 tgcttacctg acggacgtcc tgctggcacc tcagacaatc cactctcagg aggcgcagcc
2041 cgaagcccag tttcccttct atgcagtatt gccacaatgc ctctcccacg atgtcaagga
2101 ctcctgtctg tcctggaggt gggagacaag gaacctccga agaggaagca agaaagccgt
2161 actgtctatg ttgtgatcct tcatcgaaca aactgatgcg aaaacttgaa tctgttactg
2221 aaatgaggag agaaggacat gtgctattga actgagccaa acacactgta aatatccaca
2281 gactccctcc cctgccccca tcccaaatga tcttgagatt tcttttaaag aagtaaattt
2341 gtccaatggc tgtaaactat aaactactgt aattaagtgc aatttcccct ctgtgtcctc
2401 tcccctctgc cctgtatata atactaaagt gtctattagt tttctttgta aaggtcagag
2461 tcaaaatttc aaaagtgatc tgtcccctct cccctcatgg agaaacatcc taagtgggaa
2521 gtgaagcccc ttgtcctctc ccgcgggcct ggacacttat ggggacagca taccttggac
2581 tgactaccag ctaactccag tctcctgaca ttaagacaca cctctggatc cctggagggg
2641 ctgaatgtag tgtgtcagag taacatgcca gcttcctgtg ggccaggagc tcagccgtgc
2701 actccctaag aaaccccagg gcagggaaac tggctgtttg atagcagaag aaaaagttgc
2761 agtctcagaa agccttccat taaaacaatt tattttatca ctaaaaaaaa aaaaaaaa
//