LOCUS BC016488 2826 bp mRNA linear HUM 25-MAR-2004
DEFINITION Homo sapiens pleckstrin homology domain containing, family M (with
RUN domain) member 2, mRNA (cDNA clone IMAGE:4387894), partial cds.
ACCESSION BC016488
VERSION BC016488.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2826)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2826)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (31-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 26 Row: p Column: 16.
FEATURES Location/Qualifiers
source 1..2826
/db_xref="H-InvDB:HIT000089001"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4387894"
/tissue_type="Bone, osteosarcoma"
/clone_lib="NIH_MGC_86"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..2826
/gene="PLEKHM2"
/gene_synonym="KIAA0842"
/db_xref="GeneID:23207"
CDS <1..1969
/gene="PLEKHM2"
/gene_synonym="KIAA0842"
/codon_start=2
/product="PLEKHM2 protein"
/protein_id="AAH16488.1"
/db_xref="GeneID:23207"
/translation="PDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQ
PLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYR
FTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREA
QELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVH
SSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRK
GATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASL
KSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDE
SLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVI
PLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAV
SKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGK
EYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNK
KKFEDALSLIHSAWQRSDSLCRGRASRDPWC"
misc_feature 1223..1528
/gene="PLEKHM2"
/gene_synonym="KIAA0842"
/note="PH; Region: PH domain. PH stands for pleckstrin
homology"
/db_xref="CDD:pfam00169"
BASE COUNT 574 a 882 c 858 g 512 t
ORIGIN
1 gccagacact atgcttgcct ccccccagga ggagggagag gggccgagca gcaccacgga
61 gagcagcgag cgctccgagc cgggcctgct gatccctgag atgaaggaca cctccatgga
121 gcgcttgggg cagcccctga gcaaggttat cgaccagctc aacgggcagc tggaccccag
181 cacctggtgc tcccgtgctg agcccccaga ccagtccttt cggaccggct ctcccgggga
241 tgccccggag aggccgccgc tttgcgactt tagtgagggg ctttcagccc caatggactt
301 ctaccgcttt accgtcgaga gtccaagcac tgttacatca ggtggcggcc accatgaccc
361 tgcagggctt ggccaaccgc tgcatgttcc tagtagccct gaggctgctg gccaagaaga
421 agagggagga ggaggagagg gacagacgcc tcggccccta gaggatacca cgagggaggc
481 tcaggagctg gaggcccagc tgtccctggt cagggagggg cctgtgtctg agccagagcc
541 tgggacccag gaggttctct gccagctcaa gcgagaccag cccagcccgt gtctgagtag
601 cgctgaggat tctggggtgg atgagggaca ggggagccct tcggagatgg tccattcctc
661 ggagttcaga gtagacaaca atcacctgct cctgctcatg atccacgtgt tccgagaaaa
721 cgaagagcag ctgttcaaaa tgatccggat gagcaccggg cacatggagg gcaacctgca
781 gctgctgtac gtgctgctca cagactgcta tgtctacctg ctccggaaag gggccacaga
841 gaagccatac ctggtggaag aggccgtttc ttacaatgaa cttgactatg tgtcggttgg
901 ccttgaccag cagacggtga agctggtgtg caccaaccgc aggaagcagt ttctgctgga
961 cacggctgat gtggcgctgg ctgagttctt tttggcttct ttgaagtcag ccatgatcaa
1021 aggctgtcga gaacctccct accccagcat cctgacggat gccaccatgg agaagctggc
1081 actggccaaa tttgtggccc aagaatcgaa gtgtgaggca tctgctgtca ccgtgcgctt
1141 ctacggcctt gtgcactggg aggaccccac agacgagtcc ctgggcccca cgccctgcca
1201 ctgctcaccc cccgagggca ccatcaccaa agaaggcatg ctgcactaca aggcgggcac
1261 ctcctacctg ggcaaggaac actggaagac gtgcttcgtg gtgctcagca acgggatcct
1321 ctaccagtac ccggaccgca ccgacgtcat ccctctgctc tcggtgaaca tgggggggga
1381 gcagtgcggt ggctgccgga gagccaacac cacggatcgg ccccacgcct tccaggtcat
1441 tctctccgac cggccctgcc tggagctaag tgccgagagc gaggccgaga tggccgagtg
1501 gatgcagcat ctctgccagg ctgtgtccaa aggggtcatc ccccagggcg tagctcccag
1561 cccctgcata ccctgctgcc tggtcctcac ggatgaccgc ctctttacgt gccatgagga
1621 ttgccagacc agcttcttcc gctctttggg cacagccaag ctgggcgaca tcagcgccgt
1681 ctccaccgag ccgggcaagg agtactgcgt cttggagttc tcccaggaca gccagcagct
1741 cctcccgccc tgggtcatct acctgagctg cacttctgaa ctggaccgat tgctgtctgc
1801 actgaactct gggtggaaaa ccatctatca ggtggacctc ccccacacgg cgatccagga
1861 agcctccaac aagaagaaat tcgaggatgc cttgagcctc atccacagcg cctggcagcg
1921 gagcgacagt ctctgccgcg gccgagcctc ccgagacccc tggtgctgag gcagagctgg
1981 ttggcgtccc tggtgggcag gaaaggaagg cacgccagcc ggcaggcaca ctgtcacggc
2041 tgttgtcatg ctgtcgggag cctacagtcc acccctgccc tgggcggcag aaccaccgag
2101 tgtggcttaa gacagggtcc ctccactcca gggatccaga tcaggtgccc ggcacccctg
2161 ggcatcctgc ccgacaggta gcgaatggag gtcgctgggg gcagagggtc cgagccctgt
2221 gggctctgcg gatgcacgcc ctcctcccgg gcctccgcct cagtctgcag aatttctgcc
2281 gagtggcacc gagaacacca tccatctaag gacgaacaaa agaaccagga gggcgggacc
2341 cccctcttcc tctcctgggt tgggggctgg ggccctgagt gcccagccat ccttgttcgt
2401 gtttgaacac tctcctggcc acgtggggaa gcgggaacac ggggtgtctg cgcatgtttc
2461 ctcctcctag ctccatcact gcgcacacag ctgcctgcct cgccagatgc aggggggcgg
2521 gcagccctcc ctggctgcca ggaggctctg catgcccaca gtcctgccct gcctgtcccc
2581 tcaacccggc agtgcctgta gcaccgagga gcaaaggggg tggatggggg gcttggagaa
2641 gggcggagcc caccagcctg gcatccatgt tgacatcttc tgactgtccc ctgcttggct
2701 ggagccaggc ccttccctag agtttcgtca agagcctcct ggggaagggg ccaggtggtc
2761 tgcctgcaca tttttaaaat aaaatagaca tgttatattg ccaaaaaaaa aaaaaaaaaa
2821 aaaaaa
//