LOCUS       BC010370                1550 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens tumor suppressor candidate 3, mRNA (cDNA clone
            MGC:13453 IMAGE:4334284), complete cds.
ACCESSION   BC010370
VERSION     BC010370.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1550)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 1550)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2001) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: ATCC/DCTD/DTP
            cDNA Library Preparation: CLONTECH Laboratories, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Institute for Systems Biology
            http://www.systemsbiology.org
            contact: amadan@systemsbiology.org
            Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
            Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 19 Row: p Column: 3
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 30410789.
FEATURES             Location/Qualifiers
     source          1..1550
                     /db_xref="H-InvDB:HIT000034905"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:13453 IMAGE:4334284"
                     /tissue_type="Skin, melanotic melanoma, high MDR."
                     /clone_lib="NIH_MGC_62"
                     /lab_host="DH10B"
                     /note="Vector: pDNR-LIB"
     gene            1..1550
                     /gene="TUSC3"
                     /gene_synonym="D8S1992"
                     /gene_synonym="MGC13453"
                     /gene_synonym="N33"
                     /gene_synonym="OST3A"
                     /db_xref="GeneID:7991"
                     /db_xref="HGNC:HGNC:30242"
                     /db_xref="MIM:601385"
     CDS             213..1256
                     /gene="TUSC3"
                     /gene_synonym="D8S1992"
                     /gene_synonym="MGC13453"
                     /gene_synonym="N33"
                     /gene_synonym="OST3A"
                     /codon_start=1
                     /product="tumor suppressor candidate 3"
                     /protein_id="AAH10370.1"
                     /db_xref="GeneID:7991"
                     /db_xref="HGNC:HGNC:30242"
                     /db_xref="MIM:601385"
                     /translation="MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLCIQLGGGQKK
                     KENLLAEKVEQLMEWSSRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVC
                     RQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRP
                     KRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLYLR
                     RNNLEFIYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQAQ
                     FVAESHIILVLNAAITMGMVLLNEAATSKGDVGKRRIICLVGLGLVVFFFSFLLSIFR
                     SKYHGYPYSFLIK"
BASE COUNT          395 a          348 c          378 g          429 t
ORIGIN      
        1 gggggccttt ccaggtcttc tcccggtgaa ccggatgctc tgtcagtctc ctcctctgcg
       61 tcctcggccg cggcccgggt ccctcgcaaa gccgctgcca tcccggaggg cccagccagc
      121 gggctcccgg aggctggccg ggcaggcgtg gtgcgcggta ggagctgggc gcgcacggct
      181 accgcgcgtg gaggagacac tgccctgccg cgatgggggc ccggggcgct ccttcacgcc
      241 gtaggcaagc ggggcggcgg ctgcggtacc tgcccaccgg gagctttccc ttccttctcc
      301 tgctgctgct gctctgcatc cagctcgggg gaggacagaa gaaaaaggag aatcttttag
      361 ctgaaaaagt agagcagctg atggaatgga gttccagacg ctcaatcttc cgaatgaatg
      421 gtgataaatt ccgaaaattt ataaaggcac cacctcgaaa ctattccatg attgttatgt
      481 tcactgctct tcagcctcag cggcagtgtt ctgtgtgcag gcaagctaat gaagaatatc
      541 aaatactggc gaactcctgg cgctattcat ctgctttttg taacaagctc ttcttcagta
      601 tggtggacta tgatgagggg acagacgttt ttcagcagct caacatgaac tctgctccta
      661 cattcatgca ttttcctcca aaaggcagac ctaagagagc tgatactttt gacctccaaa
      721 gaattggatt tgcagctgag caactagcaa agtggattgc tgacagaacg gatgttcata
      781 ttcgggtttt cagaccaccc aactactctg gtaccattgc tttggccctg ttagtgtcgc
      841 ttgttggagg tttgctttat ttgagaagga acaacttgga gttcatctat aacaagactg
      901 gttgggccat ggtgtctctg tgtatagtct ttgctatgac ttctggccag atgtggaacc
      961 atatccgtgg acctccatat gctcataaga acccacacaa tggacaagtg agctacattc
     1021 atgggagcag ccaggctcag tttgtggcag aatcacacat tattctggta ctgaatgccg
     1081 ctatcaccat ggggatggtt cttctaaatg aagcagcaac ttcgaaaggc gatgttggaa
     1141 aaagacggat aatttgccta gtgggattgg gcctggtggt cttcttcttc agttttctac
     1201 tttcaatatt tcgttccaag taccacggct atccttatag ctttttaatt aaatgaagcc
     1261 aagtgggatt tgcataaagt gaatgtttac catgaagata aactgttcct gactttatac
     1321 tattttgaat tcattcattt cattgtgatc agctagctta ttcttgtgta ctttttttaa
     1381 actgtgggtt ttcctagtaa atttaattta cagaaatcaa tggtagcatt tagtaatcta
     1441 caaaggaaat atcaaagtgt ttttcaagcc tgttatattc agtgtgtgcc acaggattga
     1501 aataaatgac aatgtaatta tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//